LOCUS       NZ_FDFR01000003        41173 bp    DNA     linear   CON 22-DEC-2024
DEFINITION  Streptococcus pneumoniae strain 2842STDY5753301, whole genome
            shotgun sequence.
ACCESSION   NZ_FDFR01000003
VERSION     NZ_FDFR01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  CONSRTM   Pathogen Informatics
  TITLE     Direct Submission
  JOURNAL   Submitted (04-FEB-2016) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_900022985.1-RS_2024_12_22
            Annotation Date                   :: 12/22/2024 02:12:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,313
            CDSs (total)                      :: 2,259
            Genes (coding)                    :: 2,086
            CDSs (with protein)               :: 2,086
            Genes (RNA)                       :: 54
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 173
            CDSs (without protein)            :: 173
            Pseudo Genes (ambiguous residues) :: 0 of 173
            Pseudo Genes (frameshifted)       :: 71 of 173
            Pseudo Genes (incomplete)         :: 93 of 173
            Pseudo Genes (internal stop)      :: 58 of 173
            Pseudo Genes (multiple problems)  :: 41 of 173
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:29:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 27494
            Orig. end                         :: 68667
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            FDFR01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..41173
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41173
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41173
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21173](+)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21173
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            343..870
                     /locus_tag="A1O50_RS04135"
                     /old_locus_tag="ERS409084_00810"
     CDS             343..870
                     /GO_function="GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251415.1"
                     /locus_tag="A1O50_RS04135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00810"
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="WP_000963728.1"
                     /sec_met_domain="HAD_2 (E-value: 4.5e-17, bitscore: 56.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIENYIPDFAVEAVYDLTVPSLQAQGIKAVLVDLDNTLIAWNNP
                     DGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVEKFGIDYVYWALKPFTFGIDRAMK
                     EFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKPLVQHDSIKTQINRTRERRVMRKIT
                     EKYGPITYKKGI"
     gene            873..1979
                     /gene="yqeH"
                     /locus_tag="A1O50_RS04140"
                     /old_locus_tag="ERS409084_00811"
     CDS             873..1979
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yqeH"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /locus_tag="A1O50_RS04140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00811"
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="WP_000391218.1"
                     /transl_table=11
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCFR
                     LRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDVLL
                     VGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHTIKEVIDKIEHYRKG
                     RDAYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIYDTPG
                     IIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQGFTAF
                     FDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTDLVISGL
                     GWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            2194..2505
                     /gene="yhbY"
                     /locus_tag="A1O50_RS04145"
                     /old_locus_tag="ERS409084_00812"
     CDS             2194..2505
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene="yhbY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /locus_tag="A1O50_RS04145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00812"
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="WP_000060169.1"
                     /transl_table=11
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDARE
                     LIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKEI"
     gene            2557..3186
                     /locus_tag="A1O50_RS04150"
                     /old_locus_tag="ERS409084_00813"
     CDS             2557..3186
                     /EC_number="2.7.7.18"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /locus_tag="A1O50_RS04150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00813"
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="WP_000151307.1"
                     /sec_met_domain="CTP_transf_like (E-value: 9.5e-38,
                     bitscore: 123.9, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVAD
                     QVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERKGI
                     SYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKAGTS
                     YPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            3186..3779
                     /gene="yqeK"
                     /locus_tag="A1O50_RS04155"
                     /old_locus_tag="ERS409084_00814"
     CDS             3186..3779
                     /EC_number="3.6.1.41"
                     /codon_start=1
                     /gene="yqeK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /locus_tag="A1O50_RS04155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00814"
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="WP_000121660.1"
                     /transl_table=11
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRFG
                     VDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDPDLKNWGNNVWHGMVGIYKIQEDLD
                     LHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKAVAY
                     ETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            3780..4280
                     /locus_tag="A1O50_RS04160"
                     /old_locus_tag="ERS409084_00815"
     CDS             3780..4280
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /locus_tag="A1O50_RS04160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00815"
                     /product="cysteine hydrolase family protein"
                     /protein_id="WP_000844718.1"
                     /transl_table=11
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIYV
                     QHIENSEAQTSEDWQLSALLNRKPVEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLCGM
                     QTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVLDYK
                     HIF"
     gene            4293..4646
                     /gene="rsfS"
                     /locus_tag="A1O50_RS04165"
                     /old_locus_tag="ERS409084_00816"
     CDS             4293..4646
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rsfS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /locus_tag="A1O50_RS04165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00816"
                     /product="ribosome silencing factor"
                     /protein_id="WP_001003001.1"
                     /transl_table=11
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMNS
                     RQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEKLW
                     HEANSVDISEALA"
     gene            4755..5495
                     /locus_tag="A1O50_RS04170"
                     /old_locus_tag="ERS409084_00817"
     CDS             4755..5495
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /locus_tag="A1O50_RS04170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00817"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_001827876.1"
                     /transl_table=11
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELAC
                     GTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKITFIEGNMLNLSNAGKYDFV
                     TCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENAEDF
                     AMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYEILLEQAGFKSF
                     KLYADFEDKEPTETSTRWFFVAQK"
     gene            5505..6602
                     /locus_tag="A1O50_RS04175"
                     /old_locus_tag="ERS409084_00818"
     CDS             5505..6602
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /locus_tag="A1O50_RS04175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00818"
                     /product="nucleotidyltransferase"
                     /protein_id="WP_000156364.1"
                     /transl_table=11
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKTVAMSGNFMQRGEPAIV
                     DKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRDYQ
                     KIADLYTEKGAEMEKFVENLPDSLSYPQKTQTMWQEFAGLDFSGNTPNHVLALAYAKAV
                     AGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQASKVI
                     WEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRYTKARV
                     RRLLTYILMQARENVLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDAMTQKAD
                     QIYQLGKPSIAEQNFGRVPIRIETN"
     gene            6840..7070
                     /locus_tag="A1O50_RS04180"
                     /old_locus_tag="ERS409084_00819"
     CDS             6840..7070
                     /GO_component="GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0097351 - toxin sequestering activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388575.1"
                     /locus_tag="A1O50_RS04180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00819"
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="WP_179130130.1"
                     /transl_table=11
                     /translation="METVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKSE
                     WDSIQETLRIAQNKELSDKVLRGMDKIRAGH"
     gene            7339..8952
                     /locus_tag="A1O50_RS04185"
                     /old_locus_tag="ERS409084_00820"
     CDS             7339..8952
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /locus_tag="A1O50_RS04185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00820"
                     /product="ribonuclease Y"
                     /protein_id="WP_000404940.1"
                     /transl_table=11
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQE
                     ATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELKQI
                     ESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAELER
                     IGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRIAGEY
                     VAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFDPIRRE
                     IARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHPDLMKIM
                     GRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAIDHEVEGSH
                     VEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGARSESLESY
                     IKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKVRKKIENNLD
                     YPGNIKVTVIRELRAVDYAK"
     gene            9082..9708
                     /gene="gmk"
                     /locus_tag="A1O50_RS04190"
                     /old_locus_tag="ERS409084_00821"
     CDS             9082..9708
                     /EC_number="2.7.4.8"
                     /GO_function="GO:0004385 - guanylate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="gmk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /locus_tag="A1O50_RS04190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00821"
                     /product="guanylate kinase"
                     /protein_id="WP_000775037.1"
                     /transl_table=11
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQR
                     PGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIE
                     VQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALMREY
                     DYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            9733..10047
                     /gene="rpoZ"
                     /locus_tag="A1O50_RS04195"
                     /old_locus_tag="ERS409084_00822"
     CDS             9733..10047
                     /EC_number="2.7.7.6"
                     /GO_function="GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="rpoZ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /locus_tag="A1O50_RS04195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00822"
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="WP_000979235.1"
                     /transl_table=11
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSEK
                     STLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGEKI
                     "
     gene            10113..12509
                     /locus_tag="A1O50_RS04200"
                     /old_locus_tag="ERS409084_00823"
     CDS             10113..12509
                     /EC_number="3.6.1.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /locus_tag="A1O50_RS04200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00823"
                     /product="primosomal protein N'"
                     /protein_id="WP_050114821.1"
                     /transl_table=11
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRIHVPFGKGN
                     RLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKISIL
                     KAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRKGLL
                     GLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLASLLES
                     YSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQAHDAVVSSIGSSQ
                     PPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFGDKVAIL
                     HSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYKQDSNPRY
                     HAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLATIPEVQVID
                     FRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECGTVDTCPNCD
                     ISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDELAELFPQARIL
                     RMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGVLNADTALNLPD
                     FRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDYEGFYAYEMGIRR
                     QLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILGPTPKPIARTHNLY
                     HYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL"
     gene            12522..13457
                     /gene="fmt"
                     /locus_tag="A1O50_RS04205"
                     /old_locus_tag="ERS409084_00824"
     CDS             12522..13457
                     /EC_number="2.1.2.9"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /gene="fmt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228: methionyl-tRNA formyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /locus_tag="A1O50_RS04205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00824"
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="WP_000163693.1"
                     /transl_table=11
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKVI
                     QETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMDFA
                     VNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDEDNVG
                     TLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTNRQLF
                     NQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGALSLKQ
                     VQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            13450..14763
                     /gene="rsmB"
                     /locus_tag="A1O50_RS04210"
                     /old_locus_tag="ERS409084_00825"
     CDS             13450..14763
                     /EC_number="2.1.1.176"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001510 - RNA methylation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="rsmB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /locus_tag="A1O50_RS04210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00825"
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="WP_001854612.1"
                     /transl_table=11
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKGL
                     VTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVNEA
                     VELAKLRKKGSEKLVNAVLRRILREGWPDIANIKRKNKRDSIAYSLPVWLVTKLKEEYG
                     EERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAGHNLF
                     ADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALDLYDHK
                     LDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRRKPDIKY
                     NKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLESHPEFEQ
                     VKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            14778..15518
                     /locus_tag="A1O50_RS04215"
                     /old_locus_tag="ERS409084_00826"
     CDS             14778..15518
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /locus_tag="A1O50_RS04215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00826"
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="WP_000406248.1"
                     /transl_table=11
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAGN
                     IASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLEVL
                     AIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKNIIT
                     QSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTETLVR
                     FANNAGGLDNITVALVSMNEEDEE"
     gene            15515..17494
                     /gene="stkP"
                     /locus_tag="A1O50_RS04220"
                     /old_locus_tag="ERS409084_00827"
     CDS             15515..17494
                     /EC_number="2.7.11.1"
                     /codon_start=1
                     /gene="stkP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /locus_tag="A1O50_RS04220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00827"
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="WP_000614540.1"
                     /sec_met_domain="Pkinase (E-value: 5.6e-57, bitscore:
                     187.3, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLR
                     TNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYIKE
                     HYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVAFAE
                     TSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIAL
                     QHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYNRRNES
                     KLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQAPKKHR
                     FKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANFEIGEEKT
                     EASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSDVIAELKEK
                     KVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKATTIQLGNYIG
                     RNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVSKPTQIVLTVA
                     KKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVEGMVVEQSPRAG
                     EKVDLNKTRVKISIYKPKTTSATP"
     gene            17609..18367
                     /locus_tag="A1O50_RS04225"
                     /old_locus_tag="ERS409084_00828"
     CDS             17609..18367
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /locus_tag="A1O50_RS04225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00828"
                     /product="threonine/serine exporter ThrE family protein"
                     /protein_id="WP_000392880.1"
                     /transl_table=11
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGIV
                     DCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAFKQ
                     LTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVEKFI
                     RIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDIMTNH
                     INSGMSKMFESLLITLALGAGTSVALVLMN"
     misc_feature    17657..17676
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.25"
                     /tool="antismash"
     gene            18369..18818
                     /locus_tag="A1O50_RS04230"
                     /old_locus_tag="ERS409084_00829"
     CDS             18369..18818
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /locus_tag="A1O50_RS04230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00829"
                     /product="threonine/serine exporter family protein"
                     /protein_id="WP_000176924.1"
                     /transl_table=11
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLIY
                     LLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTAFF
                     VTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     misc_feature    complement(18837..18851)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 27.71"
                     /tool="antismash"
     gene            <18880..>19320
                     /locus_tag="A1O50_RS04240"
                     /pseudo=""
     CDS             18880..>19320
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /locus_tag="A1O50_RS04240"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="transposase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVREYRTYEEIAADFGIHESNLLRRSQWVEVTLVQSGVTISKTHL
                     SAENTVIVDATEVKINRPKKIN"
     assembly_gap    19321..19394
                     /estimated_length=74
                     /gap_type="unknown"
                     /linkage_evidence="unspecified"
     gene            <19395..19554
                     /locus_tag="A1O50_RS13465"
                     /pseudo=""
     CDS             <19397..19554
                     /codon_start=2
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /locus_tag="A1O50_RS13465"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="NHALSKERSKVENIFAKVKTFKMISTTYRNHRKRFGLRMNLIVGI
                     INHELGF"
     gene            19622..19870
                     /locus_tag="A1O50_RS04245"
                     /old_locus_tag="ERS409084_00831"
     CDS             19622..19870
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /locus_tag="A1O50_RS04245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00831"
                     /product="hypothetical protein"
                     /protein_id="WP_001818278.1"
                     /transl_table=11
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFYQ
                     KFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            20001..21173
                     /locus_tag="A1O50_RS04250"
                     /old_locus_tag="ERS409084_00832"
     CDS             20001..21173
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /locus_tag="A1O50_RS04250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00832"
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_000151960.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 8e-09, bitscore:
                     29.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSIA
                     PLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFARS
                     FEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAMLIT
                     QNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQKRYQL
                     TLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGNIYTGS
                     LFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLNKLNQRT
                     ALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            21173..22447
                     /locus_tag="A1O50_RS04255"
                     /old_locus_tag="ERS409084_00833"
     CDS             21173..22447
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /locus_tag="A1O50_RS04255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00833"
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_053039714.1"
                     /transl_table=11
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTVA
                     DQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFTAQ
                     VHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVEQIK
                     GEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSLVTAS
                     CRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIATGNDWR
                     AIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPIATKGGSIGLNPRVALSHD
                     LLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGASESEVAP
                     LVERLISDKTFNLETAQRYLENLRS"
     gene            complement(22483..23448)
                     /locus_tag="A1O50_RS04260"
                     /old_locus_tag="ERS409084_00834"
     CDS             complement(22483..23448)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /locus_tag="A1O50_RS04260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00834"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_000225999.1"
                     /transl_table=11
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMRELG
                     YKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDSEK
                     EREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAGGVL
                     AAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKEMEIK
                     NILTREKPDAIFASDDLTAILIIKIAQELGISVPKELKVIGYDGTYFIENYYPQLATIK
                     QPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(23429..24883)
                     /locus_tag="A1O50_RS04265"
                     /old_locus_tag="ERS409084_00835"
     CDS             complement(23429..24883)
                     /EC_number="3.2.1.26"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /locus_tag="A1O50_RS04265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00835"
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="WP_061751129.1"
                     /transl_table=11
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGLL
                     NDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFRETGVKVLPDTPLDSHG
                     AYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPADSTD
                     HFRDPQIFNFKGQYYAVVGGQNLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRTAYMM
                     ECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQLQNMD
                     YGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDCFDHQGTFSLVKELTIKDDKLYQYP
                     VAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSINFDLVNGQ
                     VTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVFSGRVFPHA
                     DQNGILIKSGNPTGTYYELDYGRKTN"
     misc_feature    complement(24960..24975)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.4"
                     /tool="antismash"
     gene            25260..27143
                     /locus_tag="A1O50_RS04275"
                     /old_locus_tag="ERS409084_00836"
     CDS             25260..27143
                     /EC_number="2.7.1.211"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145: Glucose-specific phosphotransferase enzyme IIA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /locus_tag="A1O50_RS04275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00836"
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="WP_001064554.1"
                     /transl_table=11
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEVI
                     ENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQRA
                     IRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPGLVV
                     WSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGSVLPA
                     FIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYILIATK
                     AILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAAMTAQGA
                     ATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAGAIGGGLA
                     SILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYEDEVDATAA
                     AKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQGIAVKPSQGV
                     VYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKVAQGNKVKAGD
                     VLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIEVKI"
     gene            27292..28179
                     /gene="scrK"
                     /locus_tag="A1O50_RS04280"
                     /old_locus_tag="ERS409084_00837"
     CDS             27292..28179
                     /EC_number="2.7.1.4"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008865 - fructokinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="scrK"
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /locus_tag="A1O50_RS04280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00837"
                     /product="fructokinase ScrK"
                     /protein_id="WP_000164302.1"
                     /transl_table=11
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKTI
                     EFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPMYF
                     TTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHYYVA
                     RHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYIAQAA
                     VNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAVAGNGS
                     ATLGNFVLAKEVSK"
     gene            complement(28499..29116)
                     /locus_tag="A1O50_RS04285"
                     /old_locus_tag="ERS409084_00838"
     CDS             complement(28499..29116)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /locus_tag="A1O50_RS04285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00838"
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="WP_000076185.1"
                     /transl_table=11
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQSK
                     ETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGIVI
                     GCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADFLCM
                     LAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(29531..>29719)
                     /locus_tag="A1O50_RS04290"
                     /pseudo=""
     CDS             complement(29531..>29719)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558115.1"
                     /locus_tag="A1O50_RS04290"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS30 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="GSNENHNRLIHRWLPQGTKKTTTKEVAFIEKWINNYPKKCLNYKS
                     PREDFWMTNLNLKFSNN"
     gene            complement(30112..30303)
                     /locus_tag="A1O50_RS13470"
     CDS             complement(30112..30303)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="A1O50_RS13470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_000836789.1"
                     /transl_table=11
                     /translation="MKSKEQTRKLAVGCSKYSFEVADKTDEVSSKHCFEVVDRTDEVSN
                     YIYGKAKLTWFEEIFEEY"
     gene            30426..31319
                     /locus_tag="A1O50_RS04300"
                     /old_locus_tag="ERS409084_00839"
     CDS             30426..31319
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /locus_tag="A1O50_RS04300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00839"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_061751131.1"
                     /transl_table=11
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIFH
                     SILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDAKE
                     VKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLDPVN
                     TELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVCNQYGKT
                     RLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIATFDQQ
                     APTIDEIFKLESGVEV"
     gene            31316..32515
                     /locus_tag="A1O50_RS04305"
                     /old_locus_tag="ERS409084_00840"
     CDS             31316..32515
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /locus_tag="A1O50_RS04305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00840"
                     /product="ABC transporter permease"
                     /protein_id="WP_050091127.1"
                     /transl_table=11
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGSS
                     MAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSVLK
                     AVYHGETSLENGIKFEVTGILNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEVKEN
                     KKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYARMMA
                     LFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILVHLGDAISLNTLLFILISLFMYVV
                     LAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPFISTFFM
                     PFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTFKRALSYK
                     "
     gene            complement(32868..33635)
                     /locus_tag="A1O50_RS04310"
                     /old_locus_tag="ERS409084_00841"
     CDS             complement(32868..33635)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /locus_tag="A1O50_RS04310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00841"
                     /product="membrane protein"
                     /protein_id="WP_000498745.1"
                     /transl_table=11
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQE
                     SQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITAKL
                     IGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLNTIS
                     GILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGLNDHF
                     YMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     misc_feature    complement(33594..33609)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.25"
                     /tool="antismash"
     gene            complement(33652..34347)
                     /locus_tag="A1O50_RS04315"
                     /old_locus_tag="ERS409084_00842"
     CDS             complement(33652..34347)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /locus_tag="A1O50_RS04315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00842"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_000054201.1"
                     /transl_table=11
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTTL
                     IKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYKDF
                     NLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPAARA
                     YILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESGESID
                     QLFRQEFKA"
     gene            complement(34352..34717)
                     /locus_tag="A1O50_RS04320"
                     /old_locus_tag="ERS409084_00843"
     CDS             complement(34352..34717)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /locus_tag="A1O50_RS04320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00843"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_000119153.1"
                     /transl_table=11
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEAG
                     VNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTHFG
                     YEKEELPGVVSDYIKGV"
     gene            34857..35330
                     /gene="nrdR"
                     /locus_tag="A1O50_RS04325"
                     /old_locus_tag="ERS409084_00844"
     CDS             34857..35330
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0140110 - transcription regulator activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nrdR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /locus_tag="A1O50_RS04325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00844"
                     /product="transcriptional regulator NrdR"
                     /protein_id="WP_001203672.1"
                     /transl_table=11
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERVE
                     ERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENEIQ
                     SEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            35331..36500
                     /locus_tag="A1O50_RS04330"
                     /old_locus_tag="ERS409084_00845"
     CDS             35331..36500
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /locus_tag="A1O50_RS04330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00845"
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="WP_000802409.1"
                     /transl_table=11
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISFW
                     DNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLVLHAPLSSQDFL
                     EHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKKVAN
                     DFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVISTKR
                     MREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQQMAGL
                     GLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRERGQKAKI
                     QKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            36501..37397
                     /gene="dnaI"
                     /locus_tag="A1O50_RS04335"
                     /old_locus_tag="ERS409084_00846"
     CDS             36501..37397
                     /codon_start=1
                     /gene="dnaI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /locus_tag="A1O50_RS04335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00846"
                     /product="primosomal protein DnaI"
                     /protein_id="WP_000446531.1"
                     /transl_table=11
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEELN
                     RSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAAIK
                     NRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGVGKS
                     FMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILDDIGA
                     EQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEARRVME
                     RIRYLAEETRLEGVNRR"
     gene            37394..38107
                     /locus_tag="A1O50_RS04340"
                     /old_locus_tag="ERS409084_00847"
     CDS             37394..38107
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /locus_tag="A1O50_RS04340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00847"
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="WP_000140846.1"
                     /sec_met_domain="PF00881 (E-value: 6.1e-23, bitscore: 76.0,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQS
                     YSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVEGL
                     LISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYPVFGMALGVP
                     NQTHDVKPRLPLDNVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQFGQA
                     EPSSTRKNLEQKKLL"
     gene            38121..39431
                     /gene="der"
                     /locus_tag="A1O50_RS04345"
                     /old_locus_tag="ERS409084_00848"
     CDS             38121..39431
                     /EC_number="3.6.5.-"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="der"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /locus_tag="A1O50_RS04345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00848"
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="WP_001207696.1"
                     /transl_table=11
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYAT
                     GEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEYVA
                     RKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIVENL
                     PNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDTDG
                     QEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGF
                     AHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQRLHKLP
                     EMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKPPTFVIFV
                     NEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     misc_feature    39486..39497
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 19.14"
                     /tool="antismash"
     gene            39522..39857
                     /locus_tag="A1O50_RS04350"
                     /old_locus_tag="ERS409084_00849"
     CDS             39522..39857
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /locus_tag="A1O50_RS04350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00849"
                     /product="hypothetical protein"
                     /protein_id="WP_000400493.1"
                     /transl_table=11
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFYS
                     LFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQELG
                     KSKGGRH"
     gene            39997..40347
                     /locus_tag="A1O50_RS04355"
                     /old_locus_tag="ERS409084_00850"
     CDS             39997..40347
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /locus_tag="A1O50_RS04355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS409084_00850"
                     /product="hypothetical protein"
                     /protein_id="WP_061751132.1"
                     /transl_table=11
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLYA
                     LFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYICFKKMLDLRRELG
                     KSKGVHKGRCRN"
     misc_feature    40745..40759
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.53"
                     /tool="antismash"
     misc_feature    41107..41122
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.33"
                     /tool="antismash"
ORIGIN
        1 tgatgagatt gagagagaac agtttgatga tgccatgatt gaggctcatc agctggtatc
       61 catgacagac ctaatctctc agattttaca gcagctttca gcctcttaca acaatattct
      121 aaacaataat ctgaatgaca atttgacaac cttgactatc atttcagtct tgctagctgt
      181 tttggcagtc gtgacaggct ttttcggaat gaatgttccc ttacctttaa cagatgagcc
      241 ccatgcttgg ctctatatca gtttggctag tgcaggtttg tggattgttt tatccttgtt
      301 actaaggaaa attgcgaaaa aaagttaaga aaaggagcca gaatggcgat tgaaaattat
      361 ataccagatt ttgctgtgga agcagtctat gatctgacag tcccaagcct gcaggcgcag
      421 ggaatcaagg ctgttttggt cgatttggat aataccctca ttgcttggaa caaccctgat
      481 ggaacgccag agatgaagca atggctacat gaccttcggg acgcgggtat tggcattatc
      541 gtagtgtcaa ataacaccaa aaaacgcgtt caacgagcag ttgagaaatt tgggattgat
      601 tacgtttact gggccttgaa gcccttcaca tttggtattg accgtgccat gaaggaattc
      661 cactatgaca aaaaggaagt ggtcatggtt ggcgaccagc tcatgacaga tatacgagca
      721 gcccaccgtg cagggattcg gtcaatttta gtcaaaccct tggtccaaca tgactcaatc
      781 aaaacgcaga ttaaccgaac tcgtgagcgt cgtgttatga gaaaaatcac tgaaaagtac
      841 ggaccgatta catataaaaa aggaatttaa ctatggaaga aattctctgt attggttgtg
      901 gagcaaccat tcagacgaca gataaagctg gtcttggttt taccccccag tcggcacttg
      961 aaaaaggttt ggagactggc gaagtctatt gccaacgctg tttccgtctc cgccactaca
     1021 atgaaatcac agatgtccag ttgacgaacg atgatttcct caagctcttg cacgaggtgg
     1081 gagacagtga tgctttagtg gtcaatgtca ttgatatctt tgattttaat ggatctgtca
     1141 tcccaggttt accacgtttc gtctcgggca atgatgtcct cttggtagga aataaaaaag
     1201 atatccttcc taagtcagtt aagtctggta agattagcca gtggctcatg aaacgtgccc
     1261 atgaagaagg tcttcgtcca gtcgatgtgg tcctaacttc agcacaaaat aaacatacca
     1321 ttaaggaagt cattgataag attgaacact accgtaaggg ccgcgatgcc tatgtggtcg
     1381 gtgtgaccaa cgttggaaaa tcaactctaa tcaatgctat tatccaagaa atcacgggtg
     1441 atcagaatgt catcacgact tcacgcttcc cagggacaac cttggacaaa atagagattc
     1501 cgcttgacga cggatcttat atttacgata cgccgggaat tatccaccgc caccagatgg
     1561 ctcactattt gacggccaaa aacctcaagt atgtcagtcc taaaaaggaa atcaagccta
     1621 agacctatca gcttaatcct gagcaaaccc tatttttagg tggtttggga cgctttgact
     1681 ttatagcagg agaaaagcaa ggatttactg ctttctttga taatgaactc aaactccatc
     1741 gtagcaagct tgaaggagct agtgctttct acgataagca cctgggaact cttctgacac
     1801 caccaaatag caaggaaaaa gaagatttcc caaggctagt ccagcatgtc tttaccatta
     1861 aagataagac agacctagtt atctcaggcc taggatggat tcgtgtaaca ggcatagcaa
     1921 aagtcgccgt ctgggcacca gaaggcgtcg ccgtcgtcac acgaaaagca attatttaag
     1981 cacagaaagg aaagggttgt ctgaatttgg gcgagcaagg cgagccccat agagaatact
     2041 tttcgctgtg gtgtaagttg gtacaagtga ttgtaccaac tgcggaaaat ttgagacctt
     2101 aggctcaaat tttagtcatg aaagtccgaa ggactttgct gacgtccgtc accacttcag
     2161 aaaagtataa aaagaaactc ttttaaagaa attatgtcat taacatcaaa acaacgtgcc
     2221 ttcctcaaca gccaggcaca caccctcaaa cctatcatcc aaatcgggaa aaatggtctc
     2281 aacgaccaaa tcaaaaccag cgtccgtcaa gctcttgatg cgcgtgaatt aatcaaggtt
     2341 actctcttac aaaacacaga tgaaaacatc cacgaagtag ctgaaatttt ggaagaagaa
     2401 attggtgtgg atacagtcca aaaaatagga cgcatcttga ttttgtttaa acaatctagc
     2461 aagaaagaaa atcgcaagat ttctaagaaa gtcaaagaaa tctaagaccg aaactccaaa
     2521 taactgtttt tatagagaaa taaaggggac tagcctatga caatcgaact attgactccc
     2581 tttaccaagg tagagttgga gccagaaatc aaggagaaaa aacgcaaaca agttgggatt
     2641 ttagggggga attttaaccc tgttcacaat gcccatctta ttgttgcgga tcaagtacgg
     2701 caacagttgg gactggatca agttctgctc atgcctgaat accaacctcc tcacgttgat
     2761 aaaaaggaaa ccatccctga acaccatcgt ctcaagatgc ttgagttggc aattgagggg
     2821 attgacggcc tagtcattga aactattgag ttggagcgca agggtatttc ctacacttac
     2881 gacaccatga agattttgac agagaagaat ccagatacgg attattactt tatcatcggt
     2941 gccgacatgg ttgactatct gcctaagtgg taccgaattg atgaactggt tgacatggtt
     3001 cagtttgtgg gggttcagcg tccacgctac aaggcaggga cttcctatcc agttatctgg
     3061 gtggacgtac cgctcatgga tatctcgtcc agcatggtgc gggacttcat tgcccaaggt
     3121 cggaaaccca actttctcct acctcagcca gtgctagact acatcgagaa ggaggggctc
     3181 tactgatgtc ctatcaagac tatatcaact gctcccgtga ggccttgttg gaaaaaatgg
     3241 cagagcttct acctgagaaa cgtctaaccc attgtctagg tgtggagcgt gctgctatgg
     3301 aattagctca gcgctttggt gtagatgttg agaaagcaag tctagcaggt cttcttcatg
     3361 actatgctaa aaagttgtca gatcaggaat ttctagactt gattgaccgt taccagctag
     3421 accctgacct caaaaactgg ggcaataatg tctggcatgg tatggtcgga atttacaaaa
     3481 ttcaggaaga tttggatttg catgattctg aaattctgcg agccattgaa attcatacag
     3541 tcggagctgg tcaaatgaca gacctagata aggtcatcta cgtcgcagac tatatcgagc
     3601 acaatcgggc atttcctgga gtggatgtgg cgcgtgagat tgcaagtcta tcgctcaata
     3661 aggcggtggc ctacgaaaca gctcgtaccg tggagtatct agctcatcag ggattcccca
     3721 tctatcccca aacccttgaa acctataacg cctttgtgca ctatttgaaa gagaactaaa
     3781 tgaagacggc ttttataatc attgatgttc agaatgtttt agtagaaact gggttccaga
     3841 caaaaagtct attgggaaaa atttcttatt tacaaaacca ggctagaagc aagaatattg
     3901 aaattatcta tgttcaacat attgagaact ctgaagctca aacatcagaa gattggcagt
     3961 tatctgcgct tttaaatcga aaacctgttg aaaaggtctt tcagaagaaa tataacagta
     4021 ttttcaaaga aactggctta aaagaatact tggataagca ggggattgaa aaattagttt
     4081 tatgtggtat gcagacagaa tattgtgtgg atacctctgt caaggttgcc tttgaatatg
     4141 gctatcagct tattgttcca gaaggtgctg tcacaacctt tgatggggat gacattccag
     4201 cagaaacgat taatgaattt tatgaggaca tttgggagga gcgctttgca gatgtcctag
     4261 attacaaaca tattttctaa aaagaggatt aaatgaacga aaaagaatta ctagaactag
     4321 tcgtgaaagc ggctgatgag aaacgtgcgg aggatatcct cgcacttgat gtacaagatt
     4381 tgactagtgt gacggactac tttgtcatca ctagctcaat gaatagccgt cagttggacg
     4441 ctatcgcagc taatatccgt gaaaaagtag ctcaagcagg ctttaaaggt agccatgtcg
     4501 aaggcgatgc agctggaggc tgggtcttac tggacctcgg tgctgttgtc gtgcatatct
     4561 tttcagaaga aatgcgtgcc cattataacc tagagaagct atggcatgag gcgaattcag
     4621 tagatatttc agaagctctt gcttagaaga tgaactcagt tgtagtcaac tgggtttctt
     4681 tgcttatttt agaaaaattg atagaaaggt aaagggctag tggtgtttac catggagctc
     4741 ttagtatcat gattatggcg acttatgaaa cctttgcggc ggtctatgat gcggtcatgg
     4801 acgatagttt atacgacaaa tggacgaatt tttctctgcg tcatttgcct aagaccaagg
     4861 agagaaagaa actcttggaa ttggcttgtg ggacaggaat tcaatcagtg cgcttctctc
     4921 aggctggttt tgatgtgact ggacttgact tgagtgcgga tatgttgaag attgcggaga
     4981 agagagcaac ttcagccaag caaaagatta cttttataga aggtaatatg ctgaatttgt
     5041 ccaatgcagg gaaatacgat tttgtcacgt gttattcgga ctctatctgc tatatgcagg
     5101 atgaggtgga agtaggggac gtctttaagg acgtgtacaa tgcgctgaat gaagagggag
     5161 ttttcatctt tgacgtgcac tcgacctacc agacagatga agtattccct ggctattcct
     5221 accatgaaaa tgcggaagat tttgccatgc tttgggatac atatgaggac gaagctcctc
     5281 actccatcgt gcatgagctg actttcttta tcaaggaggc tgacggttcc tttagtcgtc
     5341 atgatgaagt acatgaggag aggacctatg agatcttgac ctatgagatc ttgctggaac
     5401 aggctggatt caagtccttc aaactctatg cagactttga ggataaggag ccaacagaaa
     5461 ctagcacccg ttggtttttt gtggcgcaga agtaggagat tagcatgacc ataacaggta
     5521 ttatcgcgga gttcaatcct tttcataatg gccataaata cctgctggat caggcagagg
     5581 gactgaaaac tgttgccatg tcagggaatt tcatgcagcg tggagagcct gctattgtgg
     5641 ataagtggac aagggcccag atggcgctgg aaaatggcgc agacttggta gtggaattgc
     5701 cctttttagt cagtgttcag gcagctgatt tctttggtca aggagctgtg gatatcttgg
     5761 atcgcttggg cattgatagt ctagtttttg ggacagagga agttcgagat tatcagaaaa
     5821 tcgctgactt atacacagag aaaggtgctg agatggagaa atttgtggaa aatctgcctg
     5881 attccctttc ctatccccag aaaacccaaa ctatgtggca ggaatttgct ggtcttgatt
     5941 tttcaggtaa tacccccaat catgttcttg ctctggccta tgccaaggcg gttgcaggac
     6001 ggaatatcaa gctgcatccg attcagcgtc agggggcagg ttaccattct gtgaataaag
     6061 atgtggactt tgcctcggcg acagccctcc gtcaacatca gaaggaccaa gatttcttag
     6121 aacgttttat gccttctgtt gccctatttg agcaggccag taaggtgatc tgggaagact
     6181 attttccctt gctccgctat caaatcttgt caaatcccga cttaaccacc atctatcagg
     6241 tcaatcaaga aatggctgtg cgcattaaag aagctattaa aacagcccag tctgtggaag
     6301 aattggtcga gttagtgact accaaacgtt acaccaaggc gcgtgtcaga cgcctattga
     6361 cctatatttt gatgcaggct agagaaaatg tcttgccaga agccattcat gtccttggat
     6421 ttactgaaaa aggtaggcaa catctcaagt ctttgaaagg tcaggtcagt ctagtcagcc
     6481 gaattggcaa agaaccttgg gatgctatga cccaaaaagc agaccagatt taccaactag
     6541 gaaagccaag tatagcagag caaaattttg gaagagtgcc gattagaata gaaacaaact
     6601 aagtctaccg aaaggtggac tttttgagat tttttacgaa taatactctt cgaaaatcaa
     6661 attcaaatcg cgtcaacgtc gccttgccgt actcaagtac agcctgcggc tagtttccta
     6721 gtttgctctt tgattttcat tgagtataaa tagatagaaa agaaaatctt gtacaagttc
     6781 ctgacaattt ctttcttttc gtgtataata gtggaaaaga gctaaaacga ggtatggtta
     6841 tggaaacagt cctttactca acattccgaa atcatttaaa ggactacatg aagaaggtaa
     6901 atgatgaatt tgagcctttg acggtggtca ataaaaatcc agatgaggac attgtagttc
     6961 tttcaaagag cgaatgggac agtattcagg aaaccctgag aatcgcccaa aataaggagt
     7021 tatcagacaa ggttttacga ggaatggata aaattcgcgc aggacactag tctaatttac
     7081 agagaatacc tgagtgaaat cttgctgttg ttagaaacaa acttcttgta tttcataatc
     7141 attaggaagt ctactgcaaa gtaggctttt tctcaagtct ctactaaact actatttcta
     7201 aaaaacaagt ttattttggt aaatgtgttc caaattcccc aaaacatatt ctattttagg
     7261 tttgtgaaaa tcactttttt atggtagaat gtaaaagaat gtatgtcatt cggaataaca
     7321 ataaaatgag gtaaaaacat ggagatcatg tcgcttgcga ttgctgtttt tgccgtcatc
     7381 attggtttag tcattggata tgtcagcatc tcagctaaga tgaaatcatc tcaggaagct
     7441 gcagagttga tgcttttaaa tgctgaacaa gaagcaacta atttacgtgg acaagctgag
     7501 cgtgaagcgg atttacttgt taatgaagcc aaacgtgaaa gcaagtctct taaaaaagaa
     7561 gcactattgg aggccaaaga agaagccaga aaataccgtg aagaagtgga cgctgaattc
     7621 aaatcagaac gtcaagaact caaacaaatc gaaagtcgtt tgacagagag agctactagc
     7681 cttgaccgta aggacgacaa tttgacgagt aaagaacaaa cacttgaaca aaaagaacaa
     7741 agtatttctg atagagcgaa aaaccttgat gcgcgtgaag agcaattaga ggaagtcgaa
     7801 agacaaaaag aagcagaact agagcgtatt ggtgctctgt ctcaggcaga agcacgagat
     7861 attatcttgg ctcagacaga ggaaaacttg accagggaga ttgccagtcg cattcgcgaa
     7921 gctgagcaag aggtcaagga acgttctgac aaaatggcca aggacatctt ggttcaagct
     7981 atgcaacgta tcgctggtga atatgtagcg gagtcaacaa actcaacagt tcatctgcca
     8041 gacgatacta tgaagggacg cattattggt cgtgaaggtc gtaacattcg tacctttgaa
     8101 agtttgacag gggtcgatgt gattatcgac gatacaccag aagtggtgac cttgtcagga
     8161 tttgatccga ttcgtcgtga gattgcccgt atgactatgg aaatgttgct caaagatggt
     8221 cgtatacatc cagctcgtat cgaagagttg gttgagaaaa accgtcaaga gattgacaat
     8281 aagattcgtg aatacggtga ggctgctgcc tatgaaattg gtgcgccaaa ccttcatcca
     8341 gacttgatga agattatggg acgtttgcag ttccgtactt catatggaca aaatgttttg
     8401 cgccattcga ttgaggttgc taagttggct ggtatcatgg cgagcgaact tggtgaaaat
     8461 gcggctcttg cccgtcgtgc tggattcctt cacgatatcg ggaaagccat tgaccatgag
     8521 gttgaaggta gccacgttga aatcggtatg gaattggccc gtaagtacaa ggaaccccca
     8581 gttgtggtga atacgattgc tagtcaccac ggagatgttg aagctgagag cgtgatagca
     8641 gttattgtcg ctgcagcaga tgccttgagc gcagcccgtc caggtgctcg tagtgagtct
     8701 cttgaaagct acatcaagcg tctccatgat ttggaagaaa ttgctaacgg ctttgaagga
     8761 gtgcaaacta gctttgccct tcaagcagga cgtgaaattc gtatcatggt caatccagga
     8821 aaaatcaagg acgacaaagt cacaatcttg gctcacaaag ttcgtaagaa aattgaaaac
     8881 aatctcgatt atccaggaaa tatcaaggta accgtgattc gcgagcttcg tgcagtagat
     8941 tatgctaaat aaataagaaa gagcagttga aaaattactg cttttttgtt acactagata
     9001 gaaagactgt aaaggataat ctggcttttt gccattattc tagagaaatg ttatttcaca
     9061 gattgactaa aaggagacac aatggcagac cgaggcttac taatcgtttt ttctggtcct
     9121 tcaggggttg gaaaaggaac ggttagaaga gagatttttg agagttctga aaaccaattt
     9181 caatattctg tatcgatgac gacacgcgca caacgtcctg gagaagtgga cggtgttgac
     9241 tatttcttcc gtactcgtga agaatttgaa gagctgattc gtcaaggaca gatgttggaa
     9301 tacgcagaat atgtcggtaa ctactatgga actcctctga cctatgtcaa tgaaaccttg
     9361 gacaagggaa tcgatgtttt ccttgaaatt gaagttcagg gtgctcttca ggtcaagaaa
     9421 aaggttccag atgctgtctt tatcttcctg acaccaccag atttggatga attgcaagat
     9481 cgcttggtag gtcgtggaac agatagtgca gaagtgattg cccaacgaat cgaaaaggcc
     9541 aaggaagaaa ttgccctcat gcgtgagtat gattatgcga ttgtcaacga tcaggtgccc
     9601 ctagctgctg aacgtgtcaa atgtgtgatt gaagcagaac acttctgtgt ggatcgtgtc
     9661 attggtcact atcaggagat gttaccaaaa tctccaacta cccgataaaa tttagaaaat
     9721 aggtacaagc aaatgatgtt aaaaccctct attgatacct tgctcgacaa ggttccttca
     9781 aaatattcac tcgtaatctt ggaagcaaaa cgtgcccacg aattggaagc aggtgcccca
     9841 gcaactcaag gttttaagtc tgaaaaatca actcttcgcg ctttagaaga aatcgaatca
     9901 ggaaacgtta caattcaccc agatccagaa ggaaaacgtg aagcagtgcg tcgccgtatc
     9961 gaagaagaaa aacgccgcaa agaagaagaa gaaaagaaaa tcaaagagca aattgctaaa
    10021 gaaaaagaag atggtgaaaa aatttaaggt tggggggact caatcttatt ttttctattg
    10081 caagaatgta ctgacaagga ggaggtgaga agatggccct agctaagatt atcgtagatg
    10141 tgcccttgat gcagacggac cagccctata gttacaggat tccggaggaa tttgagggaa
    10201 tgctggaagt tgggatgcgg attcatgtgc cttttggtaa ggggaatcgc ctgattcaag
    10261 ggattgttct tggtttggag tcccaatcag atggagaaga gatggagcaa gatttaaaag
    10321 atattgcaga ggtgctggat ttttctcctg ttctcacgcc agaacaactc tggctggctg
    10381 aggagttacg caaatctgtc ttctcctaca aaatctctat cctcaaggcc atgcttccag
    10441 gatttctgaa ttctagctat gacaagattc tctatcctct ggaaggcttg agtcaggaag
    10501 aacgagtacg cctgtttggt tcagaagatt cgctagcctt ttcttcacta gaccttgcca
    10561 agcaagctga aatgatgcgt ttgactagaa aaggcctgct tggtctggaa tatcaggcag
    10621 tcgatcaaaa gaaggtcaag acccagtctt ggtatgaggt tgaccatgct caattagaag
    10681 gtgttgagat ttctacacgt gccaagaaaa agttggaact gagagattat ctgctgtctc
    10741 atccagagag cgcttccttg gctagcttgt tagagtccta ctcgcgagag caagtcaact
    10801 tctttgtgga tcaaggtgct gttaccatag tccaaaagga agttcaacgc tcggctgctt
    10861 attttgaagg aattgaagca agtagacctt tggagttaaa tccagaacaa agacaggcgc
    10921 atgatgcggt tgtgagttct attggcagtt ctcaacctcc ctttctactt caagggatta
    10981 caggaagtgg gaagaccgag gtttacttgc agattatcca aggtgccctg gataagggca
    11041 agacagctat tttgctggta cctgagattt ccttgactcc tcaaatgacc gagcgtttta
    11101 tagcacgctt tggggacaag gtagccattc ttcactcagg attatccaat ggtgaaaagt
    11161 atgatgaatg gcgcaaggtg gagcgtggcg atgcccaagt tgttgttggt gccagatctg
    11221 ctatctttgc tcctctgaaa aatctgggtg tcatgattat tgatgaagag catgaagcgg
    11281 cttataagca ggacagcaat ccccgttacc atgccagaga ggtagctatt ttacgggctc
    11341 agtataatca agcaactctg gtacttggat ctgcaacgcc gagcttagag agccgggcac
    11401 gtgctggcaa aggcgtctat caacacttac gtctaaccca acgtgccaat cctttggcta
    11461 caatccctga ggttcaagtg attgactttc gagactatat cggacaaaat gagacgtcaa
    11521 actttacgcc tcctttgcta gaggctatcc aagaccgtct ggttaaaaaa gagcaggtgg
    11581 ttctcatgct caatcgccgt ggttattcta gctttgtcat gtgtcgggag tgtgggacgg
    11641 tggatacttg tcccaactgc gatatttctc tgaccttgca tatggatacc aagactatga
    11701 actgccatta ttgtggtttc tcgaaggata ttcctcaggt ctgtcctaac tgtaagagcc
    11761 acagtattcg ttactatggg acgggaactc agaaggctta tgatgagcta gcagaactct
    11821 ttccccaagc tcgcattttg aggatggatg tggatacgac tcgaaagaaa ggcagtcacc
    11881 aagccttgct tgaccagttt gggcgagggg aagcggatat tttacttggt actcagatga
    11941 ttgcaaaggg tttggatttt cccaatgtta ccctagtcgg agttctaaat gcggatacgg
    12001 ccttgaatct gcctgatttc cgttcttctg agagaacctt ccagctcttg actcaggtgg
    12061 caggtcgagc aggtcgggct gaaaaagcag gtcaagtctt gatacagtcc tacaatccgc
    12121 agcactatgc tattcgattt gccaaggatc aagattacga aggcttttat gcctatgaaa
    12181 tgggaatcag acgacaactc ggctatccac cttactattt cacgattggt attacccttt
    12241 ctcacaagaa agaagaagag gttttcaaac gtgcctatga agtcatgaac attttgcggt
    12301 caggcttgtc agagaccagt cccattctgg ggccaacgcc aaaaccgatt gcccgtaccc
    12361 acaacctcta tcattaccag attttaatta aataccgttt agaagatgag ctggggccga
    12421 ccctcaacca ggtcctggcc ttgactcaag aacgggaaaa tagtgagctc cgtctcagca
    12481 ttgaccatga gccgcagcaa tttttataag aaggagaaga tatgacaaaa ctaatcttta
    12541 tggggacccc cgacttttca gcaacagtct taaaaggact tttgacagat gaccgttacg
    12601 aaattctagc cgttgtgacc cagccagacc gtgctgttgg tcgtaaaaaa gttatccaag
    12661 aaaccccagt caagcaggct gccaaggaag caggattatc tatctaccaa cctgaaaaat
    12721 tatctggaag tccagagatg gaagatctta tgaagctagg agcagatgga attgtgactg
    12781 ctgcttttgg gcagtttctc ccaagcaaac tccttgatag catggacttt gctgtcaacg
    12841 ttcatgcctc cctccttcct agacaccgtg gtggtgcgcc tatccattat gccttgattc
    12901 aaggggatga ggaagctggt gtgaccatca tggaaatggt taaggaaatg gatgcaggag
    12961 atatgatttc tcgtcgcagc attccgatca cagatgagga caatgttggc accttgtttg
    13021 aaaaattggc gctagttggt cgtgatttgc ttttggacac tctgcctgcc tatattgctg
    13081 gtgatatcaa acctgaaccg caggatacga gtcaggttac cttctctcca aatataaagc
    13141 cagaggaaga aaaactggac tggaacaaaa ccaatcgtca actctttaac caaattcgtg
    13201 gaatgaaccc ctggcctgtt gcccatactt tccttaaggg cgaccgcttt aagatttatg
    13261 aagccctacc agtagaaggt cagggaaatc caggtgagat tctctctatc ggcaagaaag
    13321 aattgattgt cgcaacggct gaaggggctc tatccctcaa acaagtgcag ccagctggta
    13381 agcctaagat ggacattgct tccttcctca acggagttgg acgtacattg actgtaggag
    13441 aacgatttgg tgactaaagt agaaacggct agaagtttag ctctagcagt gctagaggat
    13501 gtttttgtga accaagcata ttcaaatatc gccttaaata aacacctcaa ggggagtcag
    13561 ctctctgcag cagacaaggg cttagtgacc gagctagtct atggaacggt agcccgtaaa
    13621 ctgactctgg aatggtacct atcccacttt atcgaagaca gagaccagtt agacagctgg
    13681 ctctatgtcc ttcttctcat gagtgcctac caactccgct atttggacaa gattccagat
    13741 catgctgtgg tcaatgaagc agtggaattg gccaaactcc gtaaaaaagg cagtgaaaaa
    13801 ttggtcaacg ctgtccttcg ccgtatcttg cgtgaaggct ggccagatat tgctaacatc
    13861 aagcgaaaaa acaagcgtga ctccattgcc tattctctcc cagtttggct agttaccaaa
    13921 ctcaaggaag aatacggaga ggagagagca aaagccatct ttgaaagcct gttagtgcga
    13981 aacaaagcta gtattcgtgt aacagaccta agtcgaaaag aggaaatcca agccttgttg
    14041 gaggcgaata attccctttt agcaaccact ggtctggtta aggagcaggg gcattttgca
    14101 gggcataatt tgtttgcgga tggagccatt accatccaag acgagtccag tcagctggtt
    14161 gctccgacgc ttgatttaca aggtgatgag cgagtgcttg atgcctgtgc ggctccaggt
    14221 gggaaaacag cccatatagc ctcttatctt acgacaggtc aggttactgc tctggacttg
    14281 tacgaccaca agttggattt aattcaagaa aatgcccaac gtctgggagt tgcagatcgg
    14341 gttcaaactc aaaaattgga tgccagaaag gtgcatgagt tttttgacca ggattccttt
    14401 gataagattt tggtggatgc tccttgttca ggaatcggtc ttttgcgccg aaaaccagat
    14461 atcaaataca ataaagaaac ggcagatttc gcgtccttgc aggaaattca gttagaaata
    14521 ttaggtagtg tttgtcaaat actaggcaaa ggtggtataa taacttatag cacctgcact
    14581 atcgtctcag aggagaattt tcaagtcgtt aaggcctttt tagagagtca tcccgagttc
    14641 gagcaggtaa aactagaaca tgaatgtaag gatatcatga aagacggctg tatcctcatt
    14701 acacctgaat tgtatggaag tgatggattc ttcatcagtc aatttcgcaa gatatcggat
    14761 taggaaggaa ctgacacatg gaaatttcat tattaacaga tgttggtcag aaacgaacaa
    14821 ataaccaaga ctatgtcaac cactatgtca atagagctgg acgtaccatg attattttag
    14881 ctgatgggat gggaggtcat cgcgcaggga atatcgctag tgaaatggcg gtgacagacc
    14941 tgggtgtagc ttgggttgat acccagatcg atacagtcaa tgaagtgcgt gaatggttcg
    15001 cccattacct agaaattgaa aatcaaaaga ttcaccaact tggtcaggat gaagcttaca
    15061 gaggcatggg aactactttg gaagtccttg ctattattga taatcaggct atctatgctc
    15121 atattggtga ttcgcgtatc ggcttgattc gtggagaaga ataccatcag ttgacgagtg
    15181 atcattcttt ggttaatgaa ttgctcaagg ctggtcaatt gacaccagaa gaggcagaag
    15241 ctcatccgca aaaaaatatt atcacccagt ctattgggca aaaagatgaa attcagcctg
    15301 attttgggac agttatcctt gagtcaggtg actatctctt gctcaatagt gacggcttga
    15361 ccaacatgat ttcaggcagt gagattcgtg atattgtaac cagtgatatt cctttagcag
    15421 ataaaacgga gacacttgtt cgttttgcta acaatgcagg aggtttagac aacattacgg
    15481 ttgcccttgt ttctatgaac gaggaggatg aagaatgatc caaatcggca agatttttgc
    15541 cggacgctat cggattgtca aacagattgg tcgaggaggc atggcggatg tctacctagc
    15601 caaagactta atcttagatg gggaagaagt ggcagtgaag gttctgagga ccaactacca
    15661 gacggacccg atagctgtag ctcgttttca gcgtgaagcg agagctatgg cagatctaga
    15721 ccatcctcat atcgttcgga taacagatat tggtgaggaa gacggtcaac agtatcttgc
    15781 aatggagtat gttgctggac tagacctcaa acgctatatc aaggaacatt atcctctttc
    15841 taatgaagaa gcagtccgta tcatgggaca aattctcttg gctatgcgct tggcccatac
    15901 tcgaggaatt gttcacaggg acttgaaacc tcaaaatatc cttttgacac cagatgggac
    15961 ggccaaggtc acagactttg ggattgctgt agcctttgca gagacaagtc tgacccagac
    16021 taactcgatg ttgggctcag ttcattactt gtcaccagag caggcgcgtg gttcgaaggc
    16081 gactgtgcag agtgatatct atgccatggg gattattttc tatgagatgt tgacaggcca
    16141 tatcccttat gacggggata gcgcggtgac cattgccctc cagcatttcc agaaacccct
    16201 gccgtccgtt attgcagaaa atccatctgt acctcaggct ttagaaaatg ttattatcaa
    16261 ggcaactgct aaaaagttga ccaatcgcta ccgctcggtt tcagagatgt atgtggactt
    16321 gtctagtagc ttgtcctaca atcgtagaaa tgaaagtaag ttaatctttg atgaaacgag
    16381 caaggcagat accaagacct tgccgaaggt ttctcagagt accttgacat ctattcctaa
    16441 ggttcaagcg cagacagaac acaaatcaat caaaaaccca agccaggctg tgacagagga
    16501 aacttaccaa ccacaagcac cgaaaaaaca tagatttaag atgcgttacc tgattttgtt
    16561 ggccagcctt gtattggtgg cagcttctct tatttggata ctatccagaa ctcctgcaac
    16621 cattgccatt ccagatgtgg caggtcagac agttgcagag gccaaggcaa cgctcaaaaa
    16681 agccaatttt gagattggtg aggagaagac agaggctagt gaaaaggtgg aagaagggcg
    16741 gattatccgt acagatcctg gcgctggaac tggtcgaaaa gaaggaacga aaatcaattt
    16801 ggttgtctca tcaggcaaac aatccttcca aattagtaat tatgtcggcc ggaaatcttc
    16861 tgatgttatc gcggaattaa aagagaaaaa agttccagat aatttgatta aaattgagga
    16921 agaagagtcg aatgagagtg aggctggaac ggtcctgaag caaagtctac cagaaggtac
    16981 gacctatgac ttgagcaagg caactcaaat tgttttgaca gtagctaaaa aagctacgac
    17041 gattcaatta gggaactata ttggacggaa ctctacagaa gtaatctcag aactcaagca
    17101 gaagaaggtt cctgagaatt tgattaagat agaggaagaa gagtccagcg aaagcgaacc
    17161 aggaacgatt atgaaacaaa gtccaggtgc cggaacgact tatgatgtga gtaaacctac
    17221 tcaaattgtc ttgacagtag ctaaaaaagt tacaagtgtt gccatgccga gttacattgg
    17281 ttccagcttg gagtttacta agaacaattt gattcaaatt gttgggatta aggaagctaa
    17341 tatagaagtt gtagaagtga cgacagcgcc tgcaggtagt gtagaaggca tggttgttga
    17401 acaaagtcct agagcaggtg aaaaggtaga cctaaataag actagagtca agatttcaat
    17461 ctacaaacct aaaacaactt cagctactcc ttaaaagcag atggataatc aaaatgagta
    17521 atcaatcttt gtcatgattt catggcaaag attttttttg agtccggatt tgtgatagaa
    17581 tagagggagt tgataaaagg aggaaagcat ggaagaatca aaagaattaa atgccgtcat
    17641 tgatgtgatt atgctagcgg ggactattct ccttaaaagt ggctcagaaa tccatcgtgt
    17701 agaagatacc atgattcgaa tcgcgcattc gcaggggatt gtggattgca atgtccttgc
    17761 catgcctgcc gctatctttt tctctattga aaataccaat atttcgcgca tgaagcgcgt
    17821 gacctcctct tcttataaca tcgaaaaagt ctgcgatgtg aaccagattt ctcgtcagct
    17881 agttgggggg cagattgact tagaaacagc ctttaagcaa ttgacggcct tgcaagctca
    17941 accccttccc tatactaagt tgcaggtaac tctggctgcg acctttagtg ctcctttctt
    18001 ttcagttatg tttagcggaa atatctacga cgcacttggg gcaggagtgg cgaccttatt
    18061 tggttttgcc ttttccctct atgtggaaaa atttatccga attccctttg tgacagcctt
    18121 tgctggagcc tttgtctttg ggataattgc ccagttttgg gctcgctaca caggttttcc
    18181 ttcaacggca gatttgatta tagctggtgc ggtcatgccg tttgtaccag gtattgcctt
    18241 gaccaatgcg gtccgtgata ttatgaccaa ccacataaac tctggtatga gtaagatgtt
    18301 tgaatccctg ctcattaccc tcgctttagg ggcaggaact tctgtcgcct tggtattgat
    18361 gaactaatat gacactaaca acctttttat tacaagcagt agcaagtttt cttgccatta
    18421 tcactttttt aatcgtactc aatgtgcaac ggtctatgct cttacctgga gggattttgg
    18481 gcatgactgt ctggctaatc tatctcttgc tcaaggaacc gaccaatgtc attgtagcta
    18541 ccttcattgc agccattatt ggttcttgtg tcagccagat tttaagtatt ctttataaga
    18601 cacctgctgt ggtctttatc ttggccattt tggcaccgct ggttccaggt tatctctcct
    18661 accgaacaac tgcctttttt gtgacagggg actataataa agcactggca agtgcgacct
    18721 tggttgtcat gttggctttg gtaatctcta ttggaatggc tagcggaaca gtgattctca
    18781 gactgtatca ttatataaaa acacatcgag tatcgtagac tttacagaaa taaaagaatt
    18841 ttctgaaaaa tgagataaat aaattaacaa cgctttctat atgtgcgaga ataccgcact
    18901 tatgaagaaa ttgcggctga ttttggtatc cacgaaagca acttactccg tcggagccaa
    18961 tgggttgaag taactcttgt tcaaagtggt gttacgattt caaaaactca tcttagtgct
    19021 gagaatacgg tgattgtgga tgcaacagag gtaaaaataa atcgtcctaa aaaaatcaac
    19081 tagccaatta ttctggtaaa aaaaatgcca cgctatgaag gctcaagcga ttgtcacaag
    19141 tcaagggaga attgtttctt tggatatcgc tgtgaactat tgtcatgata tgaagttgtt
    19201 caaaatgagt cgcagaaata tcggacaagc tggtaaaatc ttggttgaca gtgattatca
    19261 agggctcatg aagatatatc ctcaagcaca aactccacgt aaatccagca aactcaagcc
    19321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19381 nnnnnnnnnn nnnntaacca tgcgctatct aaggagagaa gcaaggttga gaacatcttt
    19441 gccaaagtaa aaacgtttaa aatgatttca acaacctatc gaaatcatcg taaacgcttc
    19501 ggattacgaa tgaatttgat tgttggtatt atcaatcatg aactaggatt ctagttttgc
    19561 aggaagtcta ctattttcct tattgtctgt aagtctactg accttgttgt ttatcccagt
    19621 catggtttct agttcgggct cagagtttca aagtggatgg caagagcatc aattgattgc
    19681 tgagaaggtt agtaaaacac ttgacaagac atttgataag gatgtcagag aaattccgac
    19741 cagtcagttt tatcaaaaat ttgtagatga gatgggaagg acttactcag gaaatttgat
    19801 cctccaggag ctgataactg tgaatggagc ttataaagct acttatatcg gtgaactctc
    19861 tagcaactaa tcattcttta aaatgatgac caataagagg cttgatttgg tgaatcaagt
    19921 cttttttctc tcttttactg ccatttgtga taaaatagta tagaacgatt ttttacatga
    19981 atgataaaac agaggtaaat atgacaatcg gtattgataa gattggtttt gcgaccagtc
    20041 aatatgtctt gaaattacaa gacttagcag aagcgagggg aattgaccct gaaaaattaa
    20101 gtaaaggact cttactcaag gaattgagta ttgcgcccct aactgaggac atcgtgacct
    20161 tggcggccag tgctagtgac tctattttaa ctgagcaaga aagacaagaa gttgacatgg
    20221 tcattgtggc taccgagtca ggaattgacc agagtaaggc tgcggccgtc tttgtgcatg
    20281 gcttgctggg catccagccc tttgctcgta gtttcgagat taaagaagcc tgctatgggg
    20341 cgacagctgc cctccattat gccaaattgc atgtggaaaa ttctccggag tccaaggtct
    20401 tggtcattgc cagtgatatt gccaaatatg gtattgaaac tccgggagaa ccaactcaag
    20461 gtgctggaag tgtagctatg ttgattacac aaaatccacg catgatggcc tttaataatg
    20521 acaatgtagc tcagacccgt gacatcatgg atttctggcg accaaattac tcgacaactc
    20581 cttatgtaaa tggtgtctat tctacccaac aatacttgga tagtttgaaa acgacttggc
    20641 ttgaatatca aaaacgctac cagcttactt tggatgattt tgcggctgtt tgtttccact
    20701 tgccttatcc taaattagcg ctaaaaggct tgaaaaaaat catggataag agcctgcctc
    20761 aagagaaaaa agacctctta caaaagcatt ttgaccagtc tattctctac agtcaaaagg
    20821 tggggaatat ctacacaggt tcacttttcc ttggactttt gtctctcttg gaaaatacag
    20881 atagcttgaa agctggggat aaaatcgccc tttatagtta cggaagtgga gctgtggctg
    20941 agttcttcag tggtgaattg gttgaaggat atgaagctta tttggataaa gaccgcttga
    21001 acaagctcaa ccaacgaact gccctatccg ttgcagacta tgaaaaggtc ttttttgagg
    21061 aagtaaactt ggatgaaaca aactctgccc agtttgctgg ctatgaaaat caagattttg
    21121 ccttggttga aattctcgac caccaacgcc gttatagcaa ggttgaaaaa taatgaagat
    21181 aagttggaat ggattttcta aaaaatcata ccaagagcgc ctcgagctgt taaaagctca
    21241 ggcgctcctt agtcctgaga gacaagctag tctggagaag gatgaacaga tgagcgtgac
    21301 tgtggcagac cagctgagtg agaatgtagt gggaactttt tctctgcctt attcactggt
    21361 tccggaggta cttgtcaacg gtcaggaata caccgttccc tatgtgacag aagaaccctc
    21421 tgtggttgcg gcggccagct atgccagcaa aatcatcaag cgtgcaggtg gttttactgc
    21481 acaagtccat cagcgacaga tgattgggca ggtagccctt tatcaagttg ctaatcctaa
    21541 actagcgcaa gagaagattg ccagcaagaa agcggagctc ttggagcttg ccaatcaagc
    21601 ctatccttct atcgttaaac gtggaggtgg ggcgcgtgat ctgcatgtcg agcagataaa
    21661 aggcgaacca gactttctcg ttgtttatat tcatgtcgat acccaggaag ccatgggtgc
    21721 caatatgctc aacaccatgc tggaagcctt gaaaccagtc ttagaagaac tcagtcaggg
    21781 acagagtctc atgggaatcc tgtccaacta cgcgaccgat tctctggtga ctgcaagctg
    21841 tcgcatcgcc tttcgctact tgagccgcca aaaggatcaa ggacgagaga ttgcggagaa
    21901 aattgcgttg gctagtcagt ttgcgcaggc tgatccttac cgagctgcta ctcataataa
    21961 aggaattttt aatggtattg atgcgatttt gattgccact ggtaatgact ggcgtgccat
    22021 cgaagctggg gcccatgcct ttgccagtcg agatggacgc tatcaaggtc ttagctgctg
    22081 gacgctggac cttgaaagag aagaattggt cggtgagatg accctgccca tgcctatagc
    22141 gactaagggt ggctctatcg gcctcaaccc acgtgtagct ctcagtcatg atctactagg
    22201 aaatccttct gccagagaat tagcccagat tatcgtgtcc atcggtcttg cccaaaattt
    22261 tgcagccctc aaagctttgg taagtacggg catccagcaa ggccacatga aactacaggc
    22321 caaatcccta gctctcctag ctggggctag tgaatctgaa gttgctcccc tagtagagcg
    22381 cctcatctca gataaaacct ttaacctaga gacagcccag cgctatctcg aaaatttaag
    22441 atcataaaaa actcagacga atcggtctga gttttcttgt gtttaaatac tttttcctgg
    22501 taatagtgta actggtaaga agtaaccagt tgtggcaact tccttgcctt caatcttttg
    22561 caagagaaga tcaatagtga gacaagcaat ctcttccaaa ggttgcttga tagtagccaa
    22621 ttgagggtag taattttcga taaagtaggt cccatcatag ccgatgacct tgagctcttt
    22681 tgggacagaa atgcccaatt cttgagcgat tttaatgatc agaatagctg tcaaatcatc
    22741 cgaagcaaaa atggcatctg gtttttcccg ggtcaagata ttcttgattt ccatttcttt
    22801 tctgacggga gaaaagtcac tggaaacatt gataatagga gcttttggga gtacggatgc
    22861 aaaaccagcg tggcgcagtc cggttggcga attggaattg tcattccctg taatcatgat
    22921 gatagactgg gcacctgtct tgaccaaggt ttgggcagca agaaccccac cagcatagtt
    22981 gtcagaggag acgacaggga tgtctggcga taggtttcgg tcaaaggaaa taatcggcgc
    23041 tgtcacacga ttgtagtctt cgattcctag gttgtgacta ccagaaatga tgccgtccac
    23101 ctgattggct tccaacattt cgatgtattc gcgttccttc tcagaatcat gttcactgtt
    23161 gcagatgatg gtcttgtaac catttttgaa gagttggtgt tccaatttat caatcaattc
    23221 tgcatagaaa acattggaaa tattggggaa aatcaagccg attaacttag ctgattttcc
    23281 ttgcagacta cgagccaggt tgttgggttt atagcccaat tctcgcatgg cttcattgac
    23341 tttttggatg gttttctcag atagataccc ttttttattg ataacccgag aaacggtagt
    23401 aggactgacg cctgcaagtt tggcgacatc agttagtttt gcgaccataa tctaattcat
    23461 agtaagttcc agttgggttt ccagatttga tcaggatacc attttggtcc gcatgtggga
    23521 agacacgacc agaaaatact ttttctcctt tattgatgaa aatttcaaag acagagttat
    23581 cgatgaagat tgtagcagta gtagcctgat tctcgatagg gcaagaacga gttgtcccaa
    23641 attcttgggc atactgttct ccagcctggc tacgatccac tgtcacttga ccgtttacaa
    23701 ggtcaaagtt gattgaaagt cccttacctt ctttatcagc aagtaagaca atctcgctct
    23761 ggctattagc ttccaagttg agttcaagtt cgtaagtgtt cttggtttgg gaacggtttg
    23821 agaaggcttc ttcagaagca cgaaggtcct taatagcagc gactggatac tggtagagct
    23881 tgtcgtcttt gatagtgagt tccttgacca aagagaaggt tccttggtga tcaaaacagt
    23941 cagatgggta agaaacatct ggcaaaccaa gccagctaac tgctagagca cgcccatcag
    24001 gagcgttgaa ggcttgagtt gcataggctt cgaaaccgta atccatgttt tgaagttgag
    24061 acacatctac cattttggca tttttagggt caaaggaagc cccaatctta tacatatttg
    24121 gaaagatatt atcgtagtct agaactttct tatccaatcc ttgtggacag tagagaagga
    24181 caggctgttc ctctacaaag accagattag gacattccat catgtaggca gtacggtcgt
    24241 tagcaaagtc aaggtcgcca actgcttgcc agtttgtgta gtcgttattg acagccttgt
    24301 agagacggac gaagcctttt ttctccaagt tctgtccacc gacgacagca tagtattgac
    24361 ctttaaagtt aaaaatttgt ggatcgcgga agtggtcagt agagtctgct ggctggtcaa
    24421 tcaagatctt gtcaatcttt gtaatcttac cctccttgtc catcaaagca ccgatttggt
    24481 atgggtgacg gatccagttt tcatcgcgaa catttcctgt ataaaatagg aataagttat
    24541 cgccaaattg catggcagaa ccagagtagg caccgtgact atctaatgga gtatctggca
    24601 aaactttgac tccagtttct ctaaagtgaa ccaaatcatc actttctagc tgtgcccaag
    24661 attttaaacc gtgggctgca ccaaaaggaa aattctggta aaagaggatc cacttgccat
    24721 caaagtaaga aaagccattt gggtcgttga gaagtcctgt ttttggctca acatggtaat
    24781 gagtatgcca tggagattgt gccatatttt cctttatatg ttgaatttct tcttgcgtcc
    24841 aatcttgata aagtctgtaa cgacgctcag ttgtccattc cattcattcc tccaaaaatc
    24901 ttatcacttt taatagtaac tgttttcgat aaaaaatgca agccttttat attaaaaaag
    24961 agaaaaaact gtcaaacgat tatcataaaa taaatacagg aaatcaatca aatttttacg
    25021 aaaatgtgaa agataatgaa ataaaagact ttttaatcaa ggtttcaaac ttatttttca
    25081 aggaatccct gatgaaacag tcaaaaacaa tcaatctaaa gcttgcccgc taagtggata
    25141 gaatattttt tctgcaaaac gcttgacata tttttaaaac atgataaaat aatagtcgta
    25201 agggcgaata aaatcgcttt caaacaagaa caaaatgtta tataaggaga tttttgcaaa
    25261 tgaacaatca ggaaattgca aaaaaagtca tcgatgcctt gggcggacgt gaaaatgtca
    25321 atagtgttgc ccactgtgcg actcgtctac gtgtcatggt caaagatgaa gagaaaatca
    25381 ataaagaagt gattgagaac ttggaaaaag ttcaaggtgc tttctttaac tcagggcaat
    25441 accaaattat ctttggtaca ggtacagtta acaaaatgta cgatgaagtt gttgtacttg
    25501 gcttaccaac atcatctaag gatgacatga aagcagaagt tgctaaacaa gggaactggt
    25561 tccaacgtgc tatccgtact ttcggtgatg ttttcgttcc aatcatccca gttatcgtag
    25621 cgacaggtct cttcatgggt gtgcgtggtc ttttcaacgc tcttgaaatg ccacttccag
    25681 gtgactttgc aacttacaca caaatcttga cagatacagc cttcatcatc ttgccaggtt
    25741 tggttgtgtg gtcaaccttc cgtgtatttg gtggaaatcc tgccgttggt atcgttcttg
    25801 gtatgatgct tgtctctggc tcacttccaa acgcttgggc agttgctcaa ggtggtgaag
    25861 taacagcgat gaacttcttt ggtttcatcc ctgttgttgg tttgcaaggt tccgttcttc
    25921 cagccttcat catcggggtt gtcggagcta aatttgaaaa agctgtccgc aaggttgttc
    25981 cagatgtcat tgacctcttg gtaacaccat tcgtgacact tttggtcatg tctatccttg
    26041 gactctttgt cattggacca gttttccacg ttgttgaaaa ctacatcctt attgctacaa
    26101 aagcgattct tagcatgcca tttggtcttg gtggtttctt gattggtggg gttcaccaat
    26161 tgatcgtcgt gtcaggtgtg caccacatct tcaacttgct tgaagtgcaa ttacttgctg
    26221 ctgaccatgc taacccattc aacgctatca tcacagctgc tatgacagct caaggtgctg
    26281 ctactgttgc ggttggtgtt aaaacaaaaa atccaaaact gaaaacactt gctttcccgg
    26341 ctgctctttc tgccttccta ggtattacag agcctgctat cttcggggtg aacttgcgct
    26401 tccgtaaacc attcttcctt tcattgattg ctggtgcaat cggtggtgga ttggcttcta
    26461 tccttggact tgctggtact ggtaatggta tcaccatcat ccctggtaca atgctttatg
    26521 ttggtaacgg acaacttcca caataccttc ttatggtagc tgtatcattt gcccttggtt
    26581 ttgctcttac ttacatgttt ggttacgaag atgaagtaga cgcaactgca gctgcaaaac
    26641 aagctgaagt ggctgaagaa aaagaagaag ttgcgccagc agctcttcaa aatgaaacac
    26701 ttgtaactcc tatcgtcggt gatgttgtcg ctcttgctga tgtcaatgac ccagtcttct
    26761 caagtggagc tatgggacaa ggtatcgctg tgaaaccaag ccaaggcgtg gtctatgcac
    26821 cagctgatgc tgaagtttca attgcctttc caacagggca cgcttttggt ttgaaaacaa
    26881 gaaatggtgc tgaagttttg attcacgttg gtattgacac tgtatctatg aacggtgacg
    26941 gttttgaagc aaaagttgct caaggtaata aggtgaaagc tggcgatgtt cttggaacat
    27001 ttgactcaaa caaaatcgct gcagctggac ttgatgatac aacaatggtt atcgttacaa
    27061 atacagctga ctacgcttca gtagctccag tcgcaacagg ttcagttgct aagggggatg
    27121 ctgtgatcga agtgaaaatc taatcaatcc tctctaatgt gaaaacgaac aaatgacatg
    27181 tttgttcgtt tttattagat agtaagattt acagaggaaa atctaaaaaa tagagacatt
    27241 tagactttcg aagtatgcta taataaagaa aataaaaaca agaggtttat catgacaaaa
    27301 ttatatggaa gcttggaagc gggcggtaca aagtttgtct gtgctgtcgg tgatgaaaac
    27361 tttaacgttg tagaaaaaac acaatttcca acaacaactc caatcgaaac aatcgataaa
    27421 accattgagt tcttctcaaa attcgataac cttgctggtc ttgcagttgg ttcatttggg
    27481 ccgattgata ttgacaaaaa ctcaaaaact tatggcttta tcacgacgac tccaaaacca
    27541 aactgggcaa atgtggactt gcttggtgcc cttcgtcgcg ccctaaacgt gccaatgtac
    27601 ttcacaacag acgtaaacag ctctgcttac ggtgaaatgg ttgcccgtaa caatgctggt
    27661 ggtcgtatcg aaaacttggt ttactacaca atcggtacag gtatcggtgc aggcgtcatc
    27721 caacgtggtg agtttatcgg tggtgtgggt caccctgaaa tgggtcatta ttatgttgct
    27781 agacacccaa tggatattga aaaagagttt aagggtgttt gtcctttcca taagggatgt
    27841 ctagaaggtt atgcagctgg tccaagtttg gaagctcgta caggtgtacg tggggaaact
    27901 attgaactca acaaccctgt ttgggatgtt caagcctact atatcgctca agctgcggtt
    27961 aatgcgacag tgactttccg cccagacgtg attgtctttg gtggaggggt catggctcaa
    28021 caacatatgc tggaccgtgt ccgtgagaaa tttacatctc ttcttaatgg ttacctacca
    28081 gtaccagatg tgcgtgacta tatcgtgacg ccagcagtcg caggaaatgg ttctgccaca
    28141 cttgggaact ttgttcttgc aaaagaagtt tcaaaataaa gcacaaaatc cgcttgggaa
    28201 accaaacgga ttttgtggtt gaaaacaata tttttgagcc tttccttaag tgattacgga
    28261 cggtagcgac tttcttcgaa attccatacc taaactttga gacactaggc tcaaagtttc
    28321 cgaatacctg aaaccattag atttcaggtg tttctatcac ggcggaaagg ctaggtaagt
    28381 cctcgcctca ctatcgaaaa atatgcatga tttccatacc aaagtatatt tagtatcaag
    28441 ctatagttaa tctacgcttt aaaaatccac ttgggaaacc aaacggattt tttacgtgtc
    28501 aaagcatttg ccagaaaaag tcaataatat aggtcaaacc gtaggtataa accacgaggg
    28561 taaagggttt ggtcagaatg atgatggtca tgtagcgctt gaaactcatc ttggtcaggg
    28621 cagccagcat acagagaaag tcagctgggc taatgggcca aatcatcata aaaataaaga
    28681 agcggtcaaa acgattgccc ttatctagcc agccgatgta cttgtcgtag gtgcgcttgc
    28741 tgacgacaga ctggacaaag gcagctccgt ataggcgcac tagataaaag ataatggcac
    28801 agccaatcac gatgccgata tagttgtaga tagtcccgat gatgtgcccg tagataaaga
    28861 ccccagccac cgaggtcaag gcccctggaa tgatagggac gacagtctgt aaaatctgta
    28921 aaaagataaa gagaggtgga ccccagatgc ctgcctgctg gataaaggca gagagggttt
    28981 ccttggattg taaaatccca gcctgataag cccaaataca gaaaatcaaa ctcccaaccc
    29041 caccgacaat cgatgagata ttgataactc gctgcagaag gggagaaaca gctttcattt
    29101 gtttatcctg tgacatgtaa actcctcata gatagtatat ttctactata ccatattttg
    29161 gaggagaaag ggggaatgag tcttttttga taaggaatag aaagtaaata gcccttcgag
    29221 acttagaata ggtctgtcaa ctaaaggtta tatgcattct aggtttcgaa taatcgcaat
    29281 tccataaatt taaaagcatt ctaagtttcg aatagcttat ctgagataat tttgaggcat
    29341 tcgcgctttc gaatagtcat tttccctaaa gtttagatgt attctgaagc tagaaagact
    29401 aaaatctaaa agtagtaaga gtctctctct gatggacgta atttatggct agtatgaatc
    29461 ctttgaattg ttagttaatt ttaatattaa tcagttctga aataattact aaatatagtt
    29521 agatggtgaa ttaattattg ctaaatttca agttcaagtt agtcatccag aagtcttctc
    29581 tgggggactt gtagttcaag cattttttag gatagttgtt aatccacttt tcgataaatg
    29641 cgacttcctt tgtagtcgtt ttcttagttc cctgaggtaa ccatctatga atgagtctgt
    29701 tgtgattttc attagatcct atagtgatgt gcataataga tatagcagat tgaaactaga
    29761 atagtataca tctacttcta aaacattgtt agaaatcaat ttgactgtcc tgatcaattt
    29821 gtcctgtttt tatttcattt tactatataa tccttagaaa acatatggga caagcggttg
    29881 aattctgttc cgtccattag tagataaagg attactcctt cttgaaatga cagatgaact
    29941 tgtttcttat aaaaatgttg tctgaaacta ttcgcctttt tccagaagtt ttagaggaag
    30001 aaaactttat gaggaaaaag gagttactca aataacaatt caggattaaa aatagacagt
    30061 tgaggagcgg aaggtataaa ttaagtttgc tactgtataa tggatttatc actaatactc
    30121 ttcgaaaatc tcttcaaacc acgtcagctt cgccttgccg tagatatagt tactgacttc
    30181 gtcagttcta tccacaacct caaaacagtg ttttgagctg acttcgtcag ttttatctgc
    30241 aacctcaaag ctgtactttg agcagcctac ggctagcttt ctagtttgct ctttgctttt
    30301 cattgagtat aaaagtgctc caggccatat tttacacagc aatagtcttc taaaaatgga
    30361 caaaaaacat tgtaaaggct atcaaaaagg agtataatga gtgcaagaaa tttcggaggt
    30421 gaaagatgct agaagtaaga agtctagaga aaagttttgg atccaagcaa gttttgtttg
    30481 gtattgactt tcaagcgcga ccaggtcgta ttttgggact agtcggaaaa aatggtgctg
    30541 gaaaaacaac gattttccat agtattttga aattcctaga atatcaggga gaaatcggtc
    30601 tggatggtca ggatattcgt caggagacct atgctcggat tggttatctg cctgaagaac
    30661 gcagtctcat gcctaaattg acagttcttg aacaagttcg ctacttggcg actctaaaag
    30721 gcatggatgc caaagaagtc aaagaaaaac tccctcaatg gatgaagagg ttggaagtga
    30781 aaggaaagct gacagataaa atcaagagtc tgtcaaaagg aaatcagcag aagattcagc
    30841 tcattattac tctgattcat gaaccagacc tgattatctt ggatgagcct tttagtggat
    30901 tggacccagt taatacagaa ttgctcaaac aagtcatttt tcaggaaaaa gagcgcggag
    30961 caaccattat cttttctgac catgtcatga ccaatgttga ggaactttgt gacgatattc
    31021 tgatgatccg agatggccgt gtggtcttgc acggaccagt tcaggatgtc tgcaatcaat
    31081 acgggaaaac gcgtctcttt gtttcaagtg aacgaagcaa ggaagaattg gaaaatcttc
    31141 ctcatgtcaa acaggtgagc ttgaccaaac aaggcagttg gaaattgatt ttggaggatg
    31201 agagcgctgg aagggaactc ttcccaatct tgactcaagg tcaatatatc gcaacatttg
    31261 accaacaagc gccaactatc gatgaaatct ttaaactaga atcaggagtg gaagtatgag
    31321 aaatatgtgg gttgtaatca aggaaaccta tcttcgacat gtcgagtcat ggagtttctt
    31381 ctttatggtg atttcgccgt tcctcttttt aggaatctct gtaggaattg ggcatctcca
    31441 aggttcttct atggctaaaa ataataaagt ggcagtagtg acaacagtgc catctgtagc
    31501 agaaggactg aagaatgtaa atggtgttaa cttcgactat aaagatgaag caagtgccaa
    31561 agaagcaatt aaagaagaaa aattaaaagg ttatttgacc attgatcaag aagatagtgt
    31621 tctaaaggca gtttatcatg gcgaaacatc gcttgaaaat ggaattaaat ttgaggttac
    31681 aggtatactc aatgaactgc aaaatcagct taatcgttca actgcttcct tgtctcaaga
    31741 gcaggaaaaa cgcttagcgc agacaattca attcacagaa aagattgatg aagtcaagga
    31801 aaataaaaag tttattcaaa caattgcagc aggtgcctta ggattctttc tttatatgat
    31861 tctgattacc tatgcgggtg taacagctca ggaagttgcc agtgaaaaag gcaccaaaat
    31921 tatggaagtc gttttttcta gcataagggc aagtcactat ttctatgcgc ggatgatggc
    31981 tctgtttcta gtgattttaa cgcatattgg gatctatgtt gtaggtggtc tggctgccgt
    32041 tttgctcttt aaagatttgc cattcttggc tcagtctggt attttggttc acttgggaga
    32101 tgctatctca ctgaataccc tgctctttat tttgatcagt cttttcatgt acgtagtctt
    32161 ggcagccttc ctaggatcta tggtttctcg tcctgaggac tcagggaaag ccttgtcgcc
    32221 tttgatgatt ttgattatgg gtggtttttt tggagtgaca gctctaggtg cagctggtga
    32281 caatctcctc ttgaagattg gttcttatat tccctttatt tcgaccttct ttatgccgtt
    32341 tcgaacgatt aatggctatg cggagggagc ggaagcatgg atttcacttg ctattacagt
    32401 gatttttgcg gtggtagcaa caggatttat cggacgcatg tatgctagtc tcgttcttca
    32461 aacggatgat ttagggattt ggaaaacctt taaacgtgcc ttatcttata aatagaagag
    32521 ccttgcgaaa gcgaggtttt taaaggtgaa aagggtggaa tcacgaacct aattatgtac
    32581 acattatgta aacaggttgc ttgaaaactc aattgtatag tgaactgaat ctggaatagg
    32641 ataatattac ttctaaaaca ttcttataaa ttgatttgaa ttccaaaatc ccatcgttcc
    32701 gttcttattt cattttgcga tatagcgaaa ggaaataagt cagctcacaa aaaacgcata
    32761 atatcaagga tttttaacac ttgatactat gcgttttcta attttaaaga ctttttgcct
    32821 ggtctctttt gttctatgag tatgttacat atctaggtaa aaattattta aagcaaatta
    32881 accttatttc tcaagatgta gtaggttccg agataaaaga tagctatgaa tatgagttct
    32941 ttaacaatgg ctatacctgc tcccatatag aaatggtcat tgagtcctac cagtgaattg
    33001 acatagaaat tggaactaag attgaagaaa agttcaataa atccaatgac gatttggata
    33061 ccaatgtagg ctgcaacagc gagtgctgta cggtattcat tgaaaagctg tccaatggaa
    33121 atagccaggt agatgcagag gattcctgaa atggtattta gtaggaagga tatacctgta
    33181 agaaagatct gagggagatg tgtttctaca aatgtaatca cataagaaag aggaatccat
    33241 tctggagctg ttaaagccag aataataaca gcacttagag ccaatacagc ggtgctaatc
    33301 aatgaccaga taaaggcacc gattagtttg gctgtgatga tatggtgttc agaaactggc
    33361 aaggtcaaag tcagatagcc ttgtcggtcg tagacactac ctttgaagcg tttaataatc
    33421 aagaaaatgg ttgaaatcgc aagtgtaagc atcaagccac caaagactgt agctagaaaa
    33481 agtagcatag tagcctgact ttcttggtaa ggtagatttt taaagccttg tgtctgtatt
    33541 ccgatgaggg cagaaaggac tagcacggct gcgtagaggg ctaaatacca cttgttaaca
    33601 tttttaaatt cgtagtgaac taaattccaa aacataaata atctcctttg cttaggcctt
    33661 aaattcctga cggaagagtt ggtcaatgga ttcacctgac tcgtagcgaa tatcatctac
    33721 atttccttga cggacgactt ttccgtcttt taggaagaca atttcatcca agattggctc
    33781 gatatcagaa atcaagtggg tagaaatcaa aacggtagaa gttggtgagt agttgttgat
    33841 aatggtattg aggatataag cacgggctgc tggatccacc ccaccaatgg gttcatccaa
    33901 aacatagaga cgagcatcac ggctcataac caaaatcagt tgaacctttt ctttgtttcc
    33961 ttttgatagt ttcttgagac gactattttc atcaatgccc aggtctgcaa gtagatgatg
    34021 agcgcgttca agattgaaat ctttatagaa ggtcttgaag taggttaggg cttctttgac
    34081 cttcatttgc tcattgagat aggtcgtatc aggcaaataa gctacaacgg ccttggttgc
    34141 tgggcttggg tccatgtcgt tgatgaggac acgtccttga tctggttgta agaggccatt
    34201 aattagttta atcagggttg tttttcctga gccgtttggc ccaagaaggc cgacaatttt
    34261 tccagctgga atgtcaagag aaacattttc aagggctggt gttgctccat atgatttgga
    34321 tacattttca aatgctagta atgacatagg cttaaactcc tttaatataa tcactgacta
    34381 cgcctggtag ttcttctttt tcatagccaa aatgggtcat ggaggaaacg aagtgttcca
    34441 attcttcttc tgataattgt ttgcgtgact gagcgattag ctccttatcc ttagtcacaa
    34501 atcgtccagt tgttcgcttg ctgtagacaa atccttctcg ttcaaggtct gataaggctc
    34561 tttggatggt attgggattg acaccagcct cgctagctag ctccctcacg gttggaagtt
    34621 gttgattggg ttccagtgta tgggaaacaa tctgaagctt gattttctcc ataatctgta
    34681 aatagatggg ttttttgttg tcaaatgtcc aggacatctt agtctccttt cttttaccct
    34741 tttgtcttaa ttaaataata caacaaaaca aaaaacttgt caagcaaaaa gaagaattgt
    34801 tttgggaatc gcttaaaaaa tggtataatg aaaagaaaac gataaggagg gaaaggatgc
    34861 gttgtccaaa atgtggggct accaagtcaa gtgttatcga tagtcgccaa gcagaagaag
    34921 ggaacaccat tcgtagaaga cgtgagtgcg acgaatgcca acaccgtttt acaacctacg
    34981 aacgagtaga agaaagaacc ttagtggttg ttaaaaaaga tggcacacgg gaacaattct
    35041 ccagagataa aatctttaat gggattatcc gctcagccca gaaacgtcct gtgtcaagtg
    35101 atgaaatcaa catggtagtc aatcgtatcg aacagaaact ccgtggtcga aatgaaaatg
    35161 aaattcaaag tgaggacatt ggttcactcg tcatggagga gttggctgaa ttggacgaga
    35221 ttacctatgt acgttttgct agtgtctatc gtagttttaa ggatgtcagt gagttagaga
    35281 gcttgctcca acaaatcacc cagtcctcta aaaagaaaaa ggaaagataa atgaagccaa
    35341 ttgaccgttt ttcttatcta aagaataatc gggtgtcgca agatacctca tctctggtac
    35401 agtgctacct cccgattatc ggtcaggagg cactgagcct ttatctttat acaatcagtt
    35461 tttgggataa tggtagaaag gaatatcttt tttcaagcat tctcaaccat cttaactttg
    35521 ggatggatag actgataaaa tcattgaaaa tcttatctgc ttttaatctc ttgaccctct
    35581 atcaaaaggg ggatgtttat cagctagtcc tccatgctcc tctatctagt caagacttct
    35641 tggagcatcc tgtttatcgc agactcttag agaaaaagat tggcgatgta gctgtggagg
    35701 atttgaaagt tgaaagtgct gatggtgaag aaatacctgt ctcactcaat caagtctttc
    35761 cagaattggc agaactaggc agtcaagaag accttggtct caagaagaaa gtggccaacg
    35821 attttgactt ggaccatttt cgccagctga tggctcgaga tggacttcgt tttgcggatg
    35881 agcagtccga tgtcttaaac ctctttgcta ttgccgagga gaagaaatgg acttggtttg
    35941 aaacctatca attggccaag tcaacagctg tttctcaggt tatttcaacc aaacgcatgc
    36001 gggaaaaaat tgctcaaaaa ccagtttcct ctgactttag tcttaaggaa acaaccatta
    36061 tcaaagaagc caaaagtaaa actgccctgc agttcttggc agaaatcaag caaacacgca
    36121 agggaaccat tacccaaaca gaaagagaac tcttgcaaca gatggctggc ttgggcttgc
    36181 tggacgaagt catcaatatc attcttttat tgacctttaa taaggtggat tcggcaaata
    36241 tcaatgagaa atatgccatg aaggtagcca atgactatgc ctatcaaaag attcattcgg
    36301 cagaaaaggc agtcttgcgc atccgtgagc gaggacagaa agcaaaaata caaaaacaga
    36361 atcagactgc cccagtaaaa accaatgttc ctaaatggag taatcctgaa tataagaatg
    36421 aaaccagcga ggaaactcgt ctggaactag aacgtaagaa gcaagaacta ttagctcgat
    36481 tagaaaaagg aggagattag atggaaagtg tcggagacgt actcaaacgt caacccagcc
    36541 gtttttatta tcaagatttg gtccagaaaa tcatgaagga ccctgatgtt gcggctttta
    36601 tccagcaaga atccttgact ccagaggaat taaatcgcag tatctccaag tttaatcagt
    36661 acatcaccga gcgtgacaag tttctccgtg gggatacgga ttatattgcc aaaggctaca
    36721 agccgatttt ggttaagaat catggctatg cagatgtttc atatgaagaa actcctgagc
    36781 taatcgcggc tgaaaaagaa gcggctatta agaaccgtct caagttaatc aatctaccag
    36841 ccagtctcaa gaaagctagt ttggctcaag ttgacttgga tgatttgggg cgcttaccag
    36901 tttttgaaaa gctactagcc ttcgtggagc aatatccagc tattcgaaaa ggtctttact
    36961 tatatggaga ctttggtgtg ggtaaaagtt tcatggtggc ggccttagct catgatttat
    37021 cagaaaaacg tggtgtttca tcaactctcc tccactatcc tagctttgtc attgatgtca
    37081 aaaatgctat cagtgatggc aatgttaaga ccttggtgga tgagattaag ctgtctgagg
    37141 tcctgatttt agatgatatt ggcgccgagc aatcaaccgt ttgggtgcgt gacgaaatcc
    37201 tgcaggtcat tctccaatat cggatgcagg aaaatttacc gacctttttc acatccaact
    37261 tcaactttga agatttggag aagcattttg cgaaagtgaa acatggaaat gacgaaacct
    37321 gggaagccag acgggtcatg gaacgcatcc gttatttggc tgaggagact cgtttagaag
    37381 gagtaaaccg tcgatgacag aaaccattaa attgatgaag gctcatactt cagtgcgcag
    37441 gtttaaagag caagaaattc cccaagtaga cttaaatgag attttgacag cagcccagat
    37501 ggcatcatct tggaagaatt tccaatccta ctctgtgatt gtggtacgaa gtcaagagaa
    37561 gaaagatgcc ttgtatgaat tggtacctca agaagccatt cgccagtctg ctgttttcct
    37621 tctctttgtc ggagatttga accgagcaga aaagggagcc cgacttcata ccgacacctt
    37681 ccaaccccaa ggtgtggaag gtctcttgat tagttcggtg gatgcggctt tggctggaca
    37741 aaatgccctg ctggcagctg aaagtttggg ttatggtggt gtgattattg gcttggtacg
    37801 gtacaagtca gaagaagtgg cagaactctt taacctgcct gactacacct atcctgtctt
    37861 tgggatggca ctaggtgttc caaatcaaac tcatgatgtg aaaccgagac tgccactaga
    37921 taatgtagtc tttgaggaag aataccaaga acagtcaact gaggcaatcc aagcttatga
    37981 ccgtgtgcag gctgactatg ctggagcgcg tgcgaccaca agctggagtc agcgtctagc
    38041 agaacagttt ggccaagcag aaccaagctc aactagaaaa aatcttgaac agaagaaatt
    38101 attgtagaaa gtgagaaatt atggccctac caactattgc cattgtagga cgtcccaatg
    38161 ttgggaaatc aaccctattt aatcggatcg ctggtgagcg aatctccatt gtagaagatg
    38221 tcgaaggagt gacacgtgac cgtatctatg caacgggtga gtggctcaat cgctctttta
    38281 gtatgattga tacaggagga attgatgatg tagatgctcc tttcatggaa caaatcaagc
    38341 accaggcaga aattgccatg gaagaagcag atgttatcgt ttttgtcgtg tctggtaagg
    38401 aaggaattac tgatgcagac gaatacgtag ctcgtaagct ttataagacc cacaaaccag
    38461 ttatcctcgc agtcaacaag gtggacaacc ctgaaatgag aaatgatatc tatgatttct
    38521 atgctctcgg tttgggtgaa ccattgccta tctcatctgt ccatggaatc ggtacagggg
    38581 atgtgctaga tgcgatcgta gaaaatcttc caaatgaata tgaagaagaa aatccagatg
    38641 tcattaagtt tagcttgatt ggtcgtccta acgttggaaa atcaagcttg atcaatgcta
    38701 tcttgggaga agaccgtgtt attgctagtc ctgttgctgg aacaactcgt gatgccattg
    38761 atacccactt tacagataca gatggtcaag agtttaccat gattgatacg gctggtatgc
    38821 gtaagtctgg taaggtttat gaaaatactg agaaatactc tgttatgcgt gccatgcgtg
    38881 ctattgaccg ttcagatgtg gtcttgatgg tcatcaatgc ggaagaaggc attcgtgagt
    38941 acgacaagcg tatcgcagga tttgcccatg aagctggtaa agggatgatt atcgtggtca
    39001 acaagtggga tacgcttgaa aaagataacc acactatgaa aaactgggaa gaagatatcc
    39061 gtgagcagtt ccaatacctg ccttacgcac cgattatctt tgtatcagct ttaaccaagc
    39121 aacgtctcca caaacttcct gagatgatta agcaaatcag cgaaagtcaa aatacacgta
    39181 ttccatcagc tgtcttgaac gatgtcatca tggatgccat tgccatcaac ccaacaccga
    39241 cagacaaagg aaaacgtctc aagattttct atgcgaccca agtggcaacc aaaccaccaa
    39301 cctttgtcat ctttgtcaat gaagaagaac tcatgcactt ttcttacctg cgtttcttgg
    39361 aaaatcaaat ccgcaaggcc tttgtttttg agggaacacc gattcatctc atcgcaagaa
    39421 aacgcaaata aaaaagtaga atctggaatg acagttccgg atttttttga tataataaaa
    39481 taatagaaaa cgctatcaaa agaaggaggg tgatgtcggt gatggaacat ttgtttaaat
    39541 tcttactttt agcaccgtac ttttattttg ataactggat tgagaaggcc aacagaaata
    39601 gtaagttttt tccaattttt tattattttt actggtttta catccccttc tattctcttt
    39661 ttagccttgc ttggacagtt gtttcagttc tgtttttcaa taccgtcttg agaaatgtga
    39721 cagatatcaa gttatggggc atttggtttc tttttattct gctagctatt ggtatgaatt
    39781 ggttaactta ttcctgtttc aaagaaatgt ttcgcttgag acaggaacta gggaagtcta
    39841 agggtggaag gcattgattt atatcggttt ctatttgtag gaggtggctt atggtacctc
    39901 taaaatcatt tattacacgc tattccaagg tttatattgg taataacatt taatagaacg
    39961 aaactaaaga aaacaattta aaaaaggagg cttgtgatgg aacacttgtt taaaatgata
    40021 atcttattac cctgttttta ctttttcagc tggattgaca aggataatag agaaagtaaa
    40081 tttttcccaa ttttttacta tttttactgg atttacatca ccctctatgc tctttttagc
    40141 cttgcttgga cagttttttc agttctgttt ttcaatatcg tcttgagaaa tttgacagat
    40201 atcaagttat ggggtatttg gctattatta ctacttatcg cttttgctag tgactggtta
    40261 gcctatatct gtttcaaaaa aatgcttgac ttgagacggg aactagggaa gtctaaaggt
    40321 gtgcataaag gaaggtgtag gaactaaaaa atgactgtat ctatgatttg tttatggagc
    40381 tatagataca gtcattttta ttttgattat gaaacttgag agaaatattc atcttgtata
    40441 gtggattgaa tatggaataa tacaatacaa cttataaaac attggtataa aatgctttag
    40501 atcccctaat tgattcgttc acattctatt acaatctact ataataaaat gatgagagtt
    40561 attacaaatt ataggtttga aaaatcatta atttcttttt cgagtatttt aactaatgcc
    40621 tcttctttgg ttagtcgtaa taaagttatt cctttatcaa tcaaatcgga gttatgttgt
    40681 agtattccca agcgtacttg agagaatcca agaatatcgt atatttttaa ttcttctgct
    40741 aataccaaaa gttgtagggt gattgtttca cattctttga ataaatgatg ttgaaaatat
    40801 acagtggaga gattggctaa aaaagatgat aaaaatactt ttgtttctcg gaagtattta
    40861 tatttctcga tggttttcat aattctatca ataagaaggg gaagattttc agaaggaaag
    40921 aaaaagagaa tggttccaag caatttcaaa tcactaatgt accatgtatc cataggttca
    40981 agatagtccc aaatttcttc agacaaatct ttcaagacgt ggttgttttt gaatccttta
    41041 gttcgtaact ctgtgacaat ttttgtatga cgatagatat tttgaatagg aacatcgtga
    41101 tgtgtcttaa gatatttttg acatttctca gtgagttcaa ccatttttct agtatcttga
    41161 aaagtagacg gat
//
