LOCUS       NZ_CP120209            20972 bp    DNA     circular CON 19-MAY-2024
DEFINITION  Chryseobacterium indologenes strain Ery-6B chromosome, complete
            genome.
ACCESSION   NZ_CP120209
VERSION     NZ_CP120209.1
KEYWORDS    RefSeq.
SOURCE      Chryseobacterium indologenes
  ORGANISM  Chryseobacterium indologenes
            Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
            Weeksellaceae; Chryseobacterium group; Chryseobacterium.
REFERENCE   1  (bases 1 to 5246911)
  AUTHORS   Xu,S.
  TITLE     Synergistic degradation of erythromycin by symbiotic bacteria Ery-6A
            and Ery-6B and application in simulated water remediation
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5246911)
  AUTHORS   Xu,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-FEB-2023) Zhejiang Agriculture and Forestry
            University, School of Environment and Resources, East Lake Campus of
            Zhejiang A&F University, Hangzhou City, Zhejiang Province, Hangzhou
            311300, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. DEC-2022
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: HiFiasm/Unicycler/Flye
            Genome Coverage                   :: 181.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_029339075.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 05:09:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,739
            CDSs (total)                      :: 4,629
            Genes (coding)                    :: 4,609
            CDSs (with protein)               :: 4,609
            Genes (RNA)                       :: 110
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 20
            CDSs (without protein)            :: 20
            Pseudo Genes (ambiguous residues) :: 0 of 20
            Pseudo Genes (frameshifted)       :: 8 of 20
            Pseudo Genes (incomplete)         :: 12 of 20
            Pseudo Genes (internal stop)      :: 4 of 20
            Pseudo Genes (multiple problems)  :: 3 of 20
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:37:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4711235
            Orig. end                         :: 4732207
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP120209.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20972
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="10"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20972
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20972
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10972](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10972
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    526..538
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: medium, score: 22.86"
                     /tool="antismash"
     gene            complement(948..2258)
                     /locus_tag="PYS58_RS21510"
                     /old_locus_tag="PYS58_21510"
     CDS             complement(948..2258)
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1076: RND efflux
                     system, outer membrane lipoprotein,"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF014385.4"
                     /locus_tag="PYS58_RS21510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_21510"
                     /product="TolC family protein"
                     /protein_id="WP_185245409.1"
                     /transl_table=11
                     /translation="MKRKFFFLIFSLITLGIFAQTLTYPTQWTLDNCIEYAKENNISIN
                     SLRLSKNSAQQDLLQAKEARYPTLNGTVSQGLFALNGNNGLHTTGAQSQSIGANSSMTL
                     YHANYINNNEASKNILVQMADLSVQESENNITLSITQAYLNILMNQENIVSLENVLKTT
                     QTQLKQGGQLYKAGSLSKLNYLQIQSQVAQDQYNLTSAQNNLRTNLVNLKQILQLPTNY
                     DFQIVKPDSIVVDSQLKPLQDVQNLAQNQRPEVKYGELNVENSNTNLKMAQASIQPTLS
                     VTGNISTNYSNGNGNYFNQLGNNFYMPIGLSLGIPIYNNRIYKTQIEKSKIAIEQASLD
                     LKNTKTILNQQIEQSYINLQNALSQYDSASQQMDISKQSYDIVNAQMKIGSIDYVQLQQ
                     QRLLYIQSIQNYLQAKYTAVLNKQIYEFYAGNPINLK"
     misc_feature    complement(2328..2345)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.76"
                     /tool="antismash"
     gene            2486..4183
                     /locus_tag="PYS58_RS21515"
                     /old_locus_tag="PYS58_21515"
     CDS             2486..4183
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004918863.1"
                     /locus_tag="PYS58_RS21515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_21515"
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_185245410.1"
                     /transl_table=11
                     /translation="MNLFTETSLSPDILKAIGELGYESPTEIQKQTIPFILSDIRDLIA
                     LAQTGTGKTAAFSLPILDMIDDTSRKIQLLVLCPTRELCLQISKDIKNYSKYMNIKTTA
                     VYGGSSIVEQMRSLKEKPQIIVGTPGRVIDLINRKALDFSAIHWLVLDEADEMLSMGFK
                     DELETILSETPETKQTFLFSATMNKEVERISKNYLTKPHRISVGSINEVKKNITHEYYV
                     VGYRQKKEALKRLIDANPNQYSIIFCRTRMETQEVADFLMQNGYAADALHGDLSQAQRD
                     TVMKKFRLKNIDILVATDVAARGLDVNSLTHVIHFSLPDDPEVFVHRSGRTGRAGKDGI
                     SMALIKPEESRKLKQIKSATKIEINERTIPTGDQIIKAQVGGVFEKLFTEHEDLFEFDD
                     SLIPDLSNFTKEELVHQLLQFQLKDLALYYKDKHDLAEQKLSSRDDDYSRRDRGRDRDR
                     DRGRDRDRGERGRDRDRGGKPRRKDENMVRFFFNLGKKDHLKKLDVLDIINKATAGGKT
                     KKRAEIGDIEILEKFSFFEVEKSFKDNVLSNIQSMKFKGKDMRAEVAN"
     gene            4335..4973
                     /locus_tag="PYS58_RS21520"
                     /old_locus_tag="PYS58_21520"
     CDS             4335..4973
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016200015.1"
                     /locus_tag="PYS58_RS21520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_21520"
                     /product="DUF47 family protein"
                     /protein_id="WP_066698712.1"
                     /transl_table=11
                     /translation="MGIGNIFHAFQPKDKIFFVLFEKVTENLVAMSEEFNAGIKDFDLN
                     DDSMLKKMSDFEHKNDELTHEIFVELGKNFITPFDREDIHTLATGLDDIADYIYASTKY
                     IFLYKSPEMKAYSDFSLLIHKACLEIQNAMKNLKGFKNMEQVKEACIKVNSIENIADDL
                     LSNSMVDLFETNDAINIIKVSSVLNYLEIVTDKAEDVANTIENIMIKYA"
     gene            4997..6139
                     /locus_tag="PYS58_RS21525"
                     /old_locus_tag="PYS58_21525"
     CDS             4997..6139
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002981299.1"
                     /locus_tag="PYS58_RS21525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_21525"
                     /product="inorganic phosphate transporter"
                     /protein_id="WP_276283917.1"
                     /transl_table=11
                     /translation="MEFPILLVVIIALALIFDYINGFHDAANSIATIVSTKVLTPFQAV
                     LWAALWNFAAFFIAAYIIGEFKIGNTIAKTVNENFITLEVIFSGLMAAIAWNLLTWWFG
                     IPSSSSHTLIGGFLGAALMHAFMMDYHDVAAAQPGLGFWDTAKEAMNQVTHQSVVKFDK
                     VIPIFLFIFMAPIIGMVISIIITLIIVHLYKRSNPHKADQSFKRLQLASSALFSLGHGL
                     NDAQKVMGIIGAALIYYHVEMLQDPIYLNIPASGRFDYFAQHYIWVPLVSFIAIALGTM
                     SGGWKIIKTMGTKITKVTSLEGVSAETAGAITLFITDHFGIPVSTTHTITGSIIGVGLT
                     KRISAVRWGITVSLLWAWVLTIPISALVAGITYLIVTFLS"
     gene            complement(6771..7748)
                     /locus_tag="PYS58_RS21530"
                     /old_locus_tag="PYS58_21530"
     CDS             complement(6771..7748)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PYS58_RS21530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PYS58_21530"
                     /product="hypothetical protein"
                     /protein_id="WP_185245412.1"
                     /transl_table=11
                     /translation="MGTGNSIGNYLPGRPSINHIVSYNENIIIVGAEVHDKAPVNKLMF
                     MAQAVRRVKISSIQTVIYFKHGYSQNMKLEFEKSLKLYKKNIKLIEVSNLNEIINYINT
                     GYTNASKNYRTKEDEYGNIYKVKNLYMYSHGMPSRITFMLDWDQYKTINKINSKETAEA
                     NELNLNNYSRLDPNSFTQNSEIWSYACRTGLSVDNDTDVEKFTWGEDRSLAQKLADRLE
                     SKVHAFLKRSNYSATWGNKSDRIDLKVADKLEKVNIHVKNDDNFRYYKKSEKKIDSLYP
                     WQPQGAYRDVIAGSSPYGPPNCMCIFQKDKSMIIPCDTMSFPKG"
     gene            complement(7732..7905)
                     /locus_tag="PYS58_RS21535"
                     /old_locus_tag="PYS58_21535"
     CDS             complement(7732..7905)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PYS58_RS21535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PYS58_21535"
                     /product="hypothetical protein"
                     /protein_id="WP_185245413.1"
                     /transl_table=11
                     /translation="MAIIKFAKNMIIKTTEKDILISGKKMIEISESKWLEATEGKLILN
                     SPKKIISNGNRK"
     gene            complement(7908..9629)
                     /locus_tag="PYS58_RS21540"
                     /old_locus_tag="PYS58_21540"
     CDS             complement(7908..9629)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002977460.1"
                     /locus_tag="PYS58_RS21540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_21540"
                     /product="phage baseplate assembly protein V"
                     /protein_id="WP_276283918.1"
                     /transl_table=11
                     /translation="MNEIQNYNLEQARQFMGKRLTVTFKYKDPEHENPERTFVGIITNV
                     SFSKEKMSLGNIVLKGYSPTILMDSAPHTQSFGGGQSVNTSIIADRVIKEALGTNDFDF
                     RVDTQNNSYINYSAQYCETHYNYLARIAEAYGEQFYYDGEVLHFGKLPPNEKSIKLIDG
                     SNVNDVTIELKAVHTKPEYFGYNSSSHTKMLGVDNRIKHLGELSAKAYELNDNIFKTRS
                     LTPTPINANMFRDVDDSQKSARGSKAVDVFTVSRETTVPFLYIGCVADLAMRKPDSNQT
                     SHFTTLMIIEVSHEVDARGYYRGSFEAIAEGTGFMPKPNFEIPKAEPQVATVISNVDPL
                     NQGRIQVQFDWQLNDTTSFIRMMSPDAGGTDAISQNRGFVAIPEIGDQVMVGFEYHNPD
                     FPFAMGGMFHGNVALGGGVNNHLKSIQTRSGIRILMNDAEGSVNIIDPSGNTYFMDGQG
                     NIMVTAPKNMTFNVGENMSINVGKNMTTTIGKNQITSVTQNITISAGNDISETATGNRM
                     EISNSRTEIADDIALRQAKKAETFSGAIGITTTEENITIQGAKTIEWNSGEKSNLY"
     gene            10001..10972
                     /locus_tag="PYS58_RS21545"
                     /old_locus_tag="PYS58_21545"
     CDS             10001..10972
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013446815.1"
                     /locus_tag="PYS58_RS21545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_21545"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_185245414.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.7e-61, bitscore:
                     204.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFLDRYQQIVGDAINKYTFKDKPTELYEPMNYIISHGGKRLRPI
                     MVLMACDLFGGDLKQAIKPALAIEFFHNFTLIHDDIMDEAPLRRNKPTIHTLHGINVGI
                     LSGDGLMLKAYKFFEDLEPEIFKACIRIFTHTGLLLCEGQQYDINFETQENVTFDDYIR
                     MITYKTGVLSASSFEIGALIAKADFKDAKAIFNFGKHIGIAFQIMDDYLDVFGDQAQFG
                     KKHAGDIYENKKTVLYLLAREHATEEERKELDYWYSKKTDNIDKIYGVEKIFRRTKVDE
                     KALRLIEKHNEIGQSYLQKIDIPEEKKKPFIELANYLLRRES"
     gene            10974..11585
                     /locus_tag="PYS58_RS21550"
                     /old_locus_tag="PYS58_21550"
     CDS             10974..11585
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PYS58_RS21550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PYS58_21550"
                     /product="hypothetical protein"
                     /protein_id="WP_276283919.1"
                     /transl_table=11
                     /translation="MIIGHYVIRTYRKFKNQGLGTRFVIVGIPLIPVQSFYIFKDTGRT
                     MEVDLYWKQAVKVYLIMISVFYLFIKYLKGSSYNEMPFEKLFLIVLTINALVYFLFDPY
                     TRKDRQIRELLSRSVYINALPKFLGQTAAYNVQSGFIRTFRENFGGANWKDMMKSGAYT
                     DQHIPFLFPIILYDLYLYENEVTKRYFDTVFKRYKELENI"
     gene            11680..12633
                     /locus_tag="PYS58_RS21555"
                     /old_locus_tag="PYS58_21555"
     CDS             11680..12633
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016200012.1"
                     /locus_tag="PYS58_RS21555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_21555"
                     /product="GSCFA domain-containing protein"
                     /protein_id="WP_185245416.1"
                     /transl_table=11
                     /translation="MKFRTEVDIPKSEKKIEIEDRIFSIGSCFASEMTELLKDGQLQTL
                     NNPFGTIFNPFSINNAVKRLHDSEFYIEDELIIYNEEYISLDHHTSFDTRYIHQTLDKI
                     NGAIEIGNAFLQEADWIIITYGSSFIYEFLPKQKLVANCHKIPQKFFEKRLLTHQELTG
                     SIYNTILELKDICKEGVQILFSVSPVRHTKDGMVENQLSKSKLITAIHESISLFEDCHY
                     LPVYEILMDDLRDYRFYKEDMIHPSTQAVNYIFDKFGDSYFSDDTKDFIKENFKIMRAL
                     EHRTNDVKDPKFIEFREKLDQRIENQRKKVKHTIFK"
     gene            12630..13151
                     /locus_tag="PYS58_RS21560"
                     /old_locus_tag="PYS58_21560"
     CDS             12630..13151
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002981293.1"
                     /locus_tag="PYS58_RS21560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_21560"
                     /product="DUF4269 domain-containing protein"
                     /protein_id="WP_185245417.1"
                     /transl_table=11
                     /translation="MIDFTKIDYLKTGNEKQRKAYALLAKHRIFEKLKEYSPTLAGTVP
                     IGIDIEGSDLDLIFEVDLRFEKDFLEDLMGSRFIPHDVRVEYPIVNGERCITLNFILEG
                     VPIEIFGQNKPTIQQNAYRHMIAEHKILEEKGEEFKQKIIELKKQGIKTEPAFGILLGL
                     ENPYEDLLKF"
     gene            13156..13923
                     /locus_tag="PYS58_RS21565"
                     /old_locus_tag="PYS58_21565"
     CDS             13156..13923
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013446676.1"
                     /locus_tag="PYS58_RS21565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_21565"
                     /product="TatD family hydrolase"
                     /protein_id="WP_276283920.1"
                     /transl_table=11
                     /translation="MIDTHTHLYAEEFDQDRKETIQRALDKGITEFYLPAIDSESHEKM
                     LQLDVEYPGKIFSMMGLHPCYVKPESWEKELEIVKNYLDQRHFPAIGEIGIDLYWDKTT
                     LDIQVKAFEQQIDWAIEKDLPIVIHTRESFDETFEVLERKKHSKLRGIFHCFSGNLEQA
                     QHAIDLNFILGIGGVVTFKNGKIDQFLNEVPLDKIVLETDSPYLAPVPHRGKRNESAYL
                     DLVAGKLVNIYGKDFSEIDRITTENAKKMFINS"
     gene            13929..15080
                     /locus_tag="PYS58_RS21570"
                     /old_locus_tag="PYS58_21570"
     CDS             13929..15080
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PYS58_RS21570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PYS58_21570"
                     /product="hypothetical protein"
                     /protein_id="WP_276283921.1"
                     /transl_table=11
                     /translation="MERLLTPKLNKTISAVVFTLYTLINLSFLVKYGVRQSVIPIYLLV
                     VVFIIVHFFIFKYSGRIFSKLTEKPFILKAFIVVITLAYMGLAHVLKDPYKLNIDRWQT
                     LEYSLRYWLEGKYIYDTKNFVGNYPSYLPGQLLIAVIFLFLGNVGYLQVAAFILFCYAV
                     IKEFKSKEIQLLGIFLLGISLSYIYEVICKSDLISSFIVVSAFILYWHRKFEKDYFKNS
                     FLLGILLGFICLTRSVVIIPLILFFMKPFLATQMSNKVKTGAGFIITFSLLLATVLLPA
                     KDFDYILKYNPLQLQGQANKYVTLFFLMITVILSFYVRNIKQVFYLASVIIFTMMGSYI
                     VETIMLGWTFDYMNVSYLATALPFCIIGYCYSRQEKSTIEHIE"
     gene            complement(15118..16428)
                     /locus_tag="PYS58_RS21575"
                     /old_locus_tag="PYS58_21575"
     CDS             complement(15118..16428)
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002981290.1"
                     /locus_tag="PYS58_RS21575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_21575"
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_276283922.1"
                     /transl_table=11
                     /translation="MNFTDLNLIEPIAKAIQEQGYTTPTPIQERSIPEILQGRDFLGCA
                     QTGTGKTAAFAIPILQNLSKNKIPNKNIKALILTPTRELAIQIEENIQAYGKYLPLKEL
                     VIFGGVKQGNQEAALKKGVDILVATPGRLLDFIAQGIISLKNLEIFVLDEADRMLDMGF
                     VHDVKRIIKLLPQKRQTLFFSATMPGEIQKLANSILNNPVKVEVTPVSSTADTIKQSVY
                     FVEKENKLNLLSHILQNDIADSVLVFSRTKHGADKIARKLQKDEISVEAIHGNKSQNAR
                     QNALNNFKSGKTRVLVATDIAARGIDIDELKFVINFELSDVSETYVHRIGRTGRAGAEG
                     TSISFVDGLDLLNLKNTEKLIGKKIPVIKNHPFHTDDLVAQKRDSNNKPVPAGGERSQK
                     PNNNSRPNNRNKRKPKPSETPSTGFKKPKNKNFTRKK"
     gene            complement(16622..17242)
                     /locus_tag="PYS58_RS21580"
                     /old_locus_tag="PYS58_21580"
     CDS             complement(16622..17242)
                     /GO_component="GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /GO_function="GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024895.4"
                     /locus_tag="PYS58_RS21580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_21580"
                     /product="porin family protein"
                     /protein_id="WP_185245421.1"
                     /transl_table=11
                     /translation="MKKNISLVLLFIISTLVSAQNSEISFGVKGGYSLSSMKFYGEKMD
                     SKSYFYAGIVAEKPISSQFSVQAEVLYTQLGGSTSYPWTQLIGNEIVDVGNMKFDYKIN
                     QIQVPISAKYYFIPKFSASVGMNIGFNISSKTKISTMFGEDTGESEGLKTVNLFPFLGA
                     EYKITEKFFVDARYNFNFFEMNKSNAVPTKIGFLQAGVGYRFK"
     misc_feature    17379..17392
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.54"
                     /tool="antismash"
     gene            complement(17457..17885)
                     /locus_tag="PYS58_RS21585"
                     /old_locus_tag="PYS58_21585"
     CDS             complement(17457..17885)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PYS58_RS21585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PYS58_21585"
                     /product="hypothetical protein"
                     /protein_id="WP_185245422.1"
                     /transl_table=11
                     /translation="MLSLKVINYLKQKDAWFEDVDIDCERYREILKDLNLDTSSDFGVF
                     YTHAEENPGGFYSKKFELWQICWMYENSDYRVINNSLRRDLNLNDNYYVISEFEGERAY
                     FYNKEKNSVEIIGYSENGMVVIEKWESFNDFLEWYFEA"
     gene            complement(18167..19150)
                     /gene="obgE"
                     /locus_tag="PYS58_RS21590"
                     /old_locus_tag="PYS58_21590"
     CDS             complement(18167..19150)
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="obgE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007841329.1"
                     /locus_tag="PYS58_RS21590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_21590"
                     /product="GTPase ObgE"
                     /protein_id="WP_185245423.1"
                     /transl_table=11
                     /translation="MSNFVDYVKIHCKSGHGGAGSAHLRREKYIPKGGPDGGDGGRGGH
                     VIMRGNAQEWTLLPLRYTRHIKAERGENGAKNQLTGADGSDIYIDVPIGTIAKNEEGEI
                     IGEILEDKQEIILMEGGKGGRGNEFFKSSTNQTPRYAQPGMEGQEGYIVFELKILADVG
                     LVGFPNAGKSTLLASVSAAKPKIANYAFTTLTPNLGIVDYRNYKSFVMADIPGIIEGAA
                     EGKGLGHRFLRHIERNSILLFLIPADSENHFQEFKILENELKEYNPELLDKDFIISVSK
                     SDLLDDELKKEISAEFPENKQPLFFSGVTGEGLVELKDAIWKQLHG"
     gene            complement(19215..19793)
                     /locus_tag="PYS58_RS21595"
                     /old_locus_tag="PYS58_21595"
     CDS             complement(19215..19793)
                     /EC_number="2.7.4.3"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA]"
                     /GO_process="GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016200008.1"
                     /locus_tag="PYS58_RS21595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_21595"
                     /product="adenylate kinase"
                     /protein_id="WP_276283923.1"
                     /transl_table=11
                     /translation="MINIVLFGPPGSGKGTQAQNLIEKFNLKQVSTGDLFRYNMKNDTE
                     LGKLAKSYIDKGELVPDQVTTDMLIDEIRKPTNTNGFIFDGYPRTTAQTEALEKIVKEE
                     LNDEIDICLSLIVEDKILVERLLKRGETSGRSDDSNVEIIENRIKEYYTKTAEVAELYK
                     QQGKYVEVNGVGEIDEIAQKLFAEVEKIK"
     misc_feature    complement(19767..19781)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 17.11"
                     /tool="antismash"
     gene            complement(19917..20471)
                     /locus_tag="PYS58_RS21600"
                     /old_locus_tag="PYS58_21600"
     CDS             complement(19917..20471)
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014938889.1"
                     /locus_tag="PYS58_RS21600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_21600"
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="WP_068941612.1"
                     /transl_table=11
                     /translation="MESIKVHDKTFVPYLKDAEIQEIVKETALRIYEDYKDEVPVFIGV
                     LNGVIMFFSDLLKYYPGECEIAFLQMSSYVGTESTGIVYQKMELTKDVKDRHIILVEDI
                     VDTGNTVESLFKYFQETQRPKSVKLASFLLKPEIYKKDFKLDYIGKEIPNKFVLGYGLD
                     YDELGRNLPNLYQLEEGQINH"
ORIGIN
        1 tataaattgt tatgtttgct gtcattcccg gctttagctt taaaccggag ttatccgcat
       61 tgatgatggt tgtataattt acaacattcg atgaaacagt agggtggagc cggacttcag
      121 caacctcacc attaaatgtt tcatcaggaa aagcatctac cgtaaaagta gctttctgac
      181 ccacttttac atttccgata tccgcttcat ctacagacgc acgaaccctc atcttggtta
      241 agtccttagc aatactaaac agggtaggag tactgaaact ggatgctacg gtctgtcctt
      301 cacttacatt cctgttgaga acagttccat ctatcggaga atagatattt gtaagagaaa
      361 ggtttttatt agcagtagaa agctgagcag ttacagtacc aacctgtgct tttgccatat
      421 tgtattggtt ggccgcaaca tcatagtctg ctttgctgat agctcctact ttataaagtt
      481 gtgattgccg gttgatattg atttcattat aggcaagatt gctttttgca ttctgcaaat
      541 tggctttata ctgctcagat tggaactgga gaagatctgg atctaaagta gccagaagtt
      601 gtcctttttt cacggtagaa ttgaaatcta cataaatatt tttgataatt ccggatacct
      661 gggtacctac cgcaacagtg tccaccggtt gaatagttcc tgttgcggta atggaatttg
      721 aaatttctcc catttcaggt tttaccgttt ccaattggat ttttatttct ttttctctga
      781 tgaagaaaaa ccagactgta cctacagcaa tgatgcctcc cacaatccag tataaccatt
      841 ttttattttt tgttttcata cgttagctat ttattgtttt ttaaaggtca tctgcaatca
      901 cgccatcttc atcggtattt gcttgtaaat catggtgatt tcattgttta cttcagattt
      961 atagggttac ctgcataaaa ttcataaatc tgtttattca gtactgcagt gtatttagcc
     1021 tgcagataat tttgaataga ttgaatgtat agcaatctct gctgttgaag ctgtacgtaa
     1081 tcaatgctgc ctattttcat ttgtgcgtta acaatgtcat aactttgttt gctgatatcc
     1141 atctgttgtg aagcggaatc atactgagat aaggcatttt gcagattgat ataggattgc
     1201 tcgatctgtt ggttaagaat tgttttagta tttttaagat caagactagc ctgttctatc
     1261 gcgatctttg atttttcaat ctgagttttg tagatcctgt tgttgtagat tggaattcca
     1321 agacttaatc cgatgggcat ataaaaattg tttcccagct gattgaaata attcccattt
     1381 ccgttagaat aattggttga aatatttccc gttacactta aagtgggttg aatggaagcc
     1441 tgagccattt taagattggt attggagttt tccacattca attctccata ttttacttca
     1501 gggcgttggt tttgggctag attctgaaca tcctgcaatg gttttagctg gctatctaca
     1561 acaatactgt ctggctttac aatctgaaaa tcataattgg tgggaagctg tagaatttgt
     1621 tttaaattta caaggttggt ccgtagatta ttctgcgctg aggttaaatt atactgatcc
     1681 tgagcaacct gtgactgaat ctggagataa ttaagtttag ataggcttcc tgctttatag
     1741 agctgccccc cttgttttaa ctgggtttgg gttgttttta aaacattttc cagggaaaca
     1801 atattttctt gattcatcaa aatattcagg taagcctgtg tgatgctcag ggtgatgttg
     1861 ttttctgact cctgtacaga taaatcagcc atctgaacaa gtatattttt tgaggcttca
     1921 ttgttgttaa tataattggc atgataaaga gtcatggaag aattggcgcc gatactttga
     1981 gattgtgcac ccgttgtatg aagcccatta ttaccattta aagcaaaaag gccttgagaa
     2041 acggttccgt tgagggtagg atatcttgct tctttggctt gaagcaaatc ctgctgggct
     2101 gaattttttg aaagccttaa tgagttgata gaaatattat tttcctttgc atattcaata
     2161 caattatcca aggtccactg agtgggataa gtgagagtct gagcaaatat tccaagcgtt
     2221 atcaatgaga atatcaaaaa gaaaaatttg cgtttcatag ttttgttttt gaaaattcat
     2281 aaataataca gaaaaaatta atccaattta ataaaaaaaa gtaatggtta acaagttttt
     2341 aacttaaagc ttgttttttt ggattaaatt tttcaaatat taaaaaagta ttaaaagatt
     2401 ctgaatttaa gattgcatat ttaaaacttt gttcaaaaac aagtcaaata tttattgtat
     2461 ctttgcaaaa attttaaaat agttaatgaa tttatttacg gaaaccagtt taagtcctga
     2521 tattcttaag gcaattggcg aactgggcta cgaaagccca acagaaatcc aaaaacagac
     2581 tatccctttt attctttcag atattcgcga tttgatcgca cttgcgcaga cagggacagg
     2641 caaaacagca gcgttttcgc ttccgatttt ggatatgatt gacgatacga gtcgcaaaat
     2701 ccaattattg gtgctttgtc cgacacggga attatgtctt cagatttcta aagacataaa
     2761 gaattactct aaatacatga acatcaaaac tactgcggtt tatggtggaa gtagtattgt
     2821 agagcaaatg agatctttaa aagagaaacc acagattatt gtgggaacgc caggtagggt
     2881 aattgacctt atcaacagaa aagcattaga cttttctgca attcattggc tggtattaga
     2941 tgaagctgat gaaatgcttt caatgggatt caaggatgaa ttggaaacca ttctaagtga
     3001 aactccggaa acgaaacaaa ctttcttatt ctcggctacg atgaataaag aagtagagag
     3061 aatttccaaa aactatctta caaagccaca ccgtatttca gtaggttcta tcaacgaagt
     3121 gaagaagaac attactcacg aatattatgt ggtaggatac cgtcagaaaa aagaagcatt
     3181 aaaaagatta attgatgcta atccgaatca gtattccatt attttctgta gaacgagaat
     3241 ggaaactcag gaggttgcag atttcttaat gcagaacggc tatgccgctg atgctcttca
     3301 cggagacctt tctcaggcac agagagatac agtaatgaag aaattcagat tgaaaaacat
     3361 tgatatcctt gtagcaacag acgttgcagc aagaggactg gatgtaaact ctctgactca
     3421 cgttatccac ttctctttac ctgatgatcc tgaagtattc gttcacagaa gcggaagaac
     3481 cggtagggct ggtaaagacg gtatttctat ggcattaatc aagccggaag aaagtagaaa
     3541 actgaaacaa atcaagtctg ctactaaaat tgaaattaac gaaagaacaa ttcctacagg
     3601 agatcagatt atcaaagctc aggttggagg tgttttcgaa aaactattca cagaacacga
     3661 agatcttttc gagtttgatg acagcttaat ccctgattta agcaacttca caaaagaaga
     3721 attagtacac cagttgttac agttccaatt gaaggatctt gctttatatt acaaagacaa
     3781 acacgatctt gctgagcaga agttaagcag cagagatgat gattactcaa gaagagaccg
     3841 tggacgtgat agagacagag atagaggtcg cgacagagat agaggagagc gtggaagaga
     3901 cagagaccgt ggtggaaaac caagaagaaa agatgagaac atggtaagat tcttcttcaa
     3961 ccttggtaaa aaagaccact tgaagaaact tgatgtttta gatattatca acaaagctac
     4021 tgctggtgga aaaactaaga aaagagctga aattggagat atcgagatcc ttgagaaatt
     4081 ctctttcttc gaagttgaaa aatcattcaa agacaatgtt ttaagcaaca ttcaatcaat
     4141 gaaatttaaa ggaaaagata tgagagctga agtagctaac taatctcttt ttatacccta
     4201 caaaaccggc agtaatgtcg gtttttttat ttggtaatca gtaggtaagc gaatgttaac
     4261 aaaacttaat gttatatagt ttcatgggcg atcctttttt aagaaatttg cacacgaatt
     4321 ataaatacta aaaaatggga attggtaata ttttccacgc ttttcaacca aaagataaaa
     4381 tcttctttgt actttttgag aaggtaactg aaaacctagt tgcaatgtct gaagaattca
     4441 acgctggaat taaggatttc gatcttaatg acgattcaat gttgaaaaaa atgagtgatt
     4501 tcgagcataa gaatgacgag cttactcacg agatcttcgt agaactaggg aaaaacttca
     4561 ttactccttt tgatcgtgag gatatccaca cattagcaac aggattagat gatattgctg
     4621 actatatcta cgcttctaca aaatatattt tcttatacaa atctcctgag atgaaagcgt
     4681 attcagattt ctctctattg atccacaaag catgtcttga aattcagaat gcaatgaaaa
     4741 accttaaagg attcaagaac atggagcagg tgaaagaagc ttgtattaaa gtaaactcta
     4801 ttgagaacat tgcagatgac ctgctttcta actcaatggt agatttattc gaaactaatg
     4861 atgccattaa cattattaaa gtttcatcgg tattgaacta tcttgaaatc gtaacggata
     4921 aagcagaaga tgttgccaat acaattgaga acatcatgat taaatacgcc taaaagataa
     4981 caatacatag caaaaaatgg aatttccgat tttacttgta gttattattg cgttggcgtt
     5041 aatctttgat tatatcaatg gttttcatga tgcagccaac tcgattgcaa ctatcgtatc
     5101 tacaaaagtt ttaactcctt tccaggctgt actttgggca gcactttgga actttgcagc
     5161 tttctttatt gctgcttata ttattggaga attcaaaatt ggtaatacaa ttgccaaaac
     5221 agttaatgag aattttatca cacttgaagt tatattttcc ggtttgatgg cagctattgc
     5281 ctggaacctt ctgacctggt ggtttggaat tccttcttca tcatcacata ccttaatcgg
     5341 aggattcctt ggagcagctt tgatgcacgc tttcatgatg gactaccatg atgtagcagc
     5401 agcacagcca ggacttggat tctgggatac agcgaaagaa gcaatgaatc aggttaccca
     5461 ccagagtgtt gtaaagtttg ataaagtaat ccctatcttc ctgttcattt tcatggcacc
     5521 gatcatagga atggttatct cgatcatcat tacattaatt attgtccacc tttataaaag
     5581 atcaaaccca cacaaagcag atcagtcttt caaaagactt cagctggctt cttcagcttt
     5641 attcagttta ggacacggtt tgaacgatgc tcagaaagta atggggatca ttggggcagc
     5701 tttaatttac tatcacgttg agatgcttca ggatccaatc tatttgaata ttcctgcttc
     5761 aggacgtttt gattattttg cacagcatta tatttgggtt cctttagttt cctttattgc
     5821 tattgcatta ggaacaatga gtgggggttg gaagatcatt aaaacaatgg gaactaaaat
     5881 cactaaagta acttcattgg aaggagtaag cgcagaaact gcaggagcga ttactttatt
     5941 tatcacagac cacttcggta ttcctgtatc tactacacac acgattacag gttctatcat
     6001 cggggtagga ttaacgaaaa gaatttcagc ggtaagatgg gggattacag taagcttact
     6061 ttgggcttgg gtattaacca ttccgatttc agcattagta gctggtatca cttatcttat
     6121 tgtaactttc ctttcctaag ataaaaaata acaattatca tataaacttt gtccgtttgg
     6181 gcaaagttta ttgtttttat taaaattgta cctcatttaa tttgctatta ttttcttcct
     6241 tttgatgact gaaaacacta tactaaaaat gaatattgag ataatgaaaa tatcaaaaaa
     6301 tgtttcaatt gaaccatatt ttttattata gtaaaaaact tctcccatgt gaagaaactc
     6361 gattaatact agcagaaata aacctataga attaaatata agtaaacttt ttgatacatt
     6421 ttgtaataaa aagtaagtag atagtattat aaggaaattg agaactatta aaaaaggtat
     6481 tgaggtatta gtgtctattt tcagaatatt atacagaaga atagttgtaa taatgatagt
     6541 gcccatattt cttttctttg ctatgaaata tagtattaat gtcattgtta aaatgataac
     6601 ccaatcataa agaattgttc tctgagtcac agcgaagcat tccgtactaa tttcgcaaag
     6661 attacctaac tcaaaagaag agttatataa gaacctatat ccaaagaaac ttattaatcc
     6721 agtaagaata tataaaataa aagatattgt attttttttc ataatattaa tcagccttta
     6781 ggaaatgaca ttgtatcaca aggaataatc atagacttgt ctttttgaaa tatacacata
     6841 caattaggag ggccataagg agagcttcca gctattacat ctctataggc tccttgtggc
     6901 tgccatgggt aaagactatc aatttttttt tcactttttt tataatatct aaagttatca
     6961 tcatttttga catgtatatt aactttttct aatttatcag caacttttaa atcaattcta
     7021 tctgatttgt ttccccatgt agcactataa ttacttcttt taagaaacgc atgaacttta
     7081 gattctaatc tatctgctag tttttgtgct aagcttctat cttctcccca tgtgaatttt
     7141 tccacatcgg tatcattatc aacacttaat cctgttctac atgcataaga ccatatttct
     7201 gaattttgag tgaagctatt tggatctaaa cgagaataat tatttagatt taattcatta
     7261 gcctctgctg tttctttaga gtttatttta ttgatagttt tgtattgatc ccaatcaagc
     7321 ataaaggtaa ttctacttgg cattccatga gaatacatat ataaattttt tactttataa
     7381 atattaccat actcatcttc ttttgttcta tagttttttg aagcatttgt ataccccgta
     7441 ttaatatagt taataatctc atttaaatta gagacttcta ttaactttat atttttctta
     7501 taaagcttta atgatttctc aaattccaat ttcatattct gagaataacc atgtttaaag
     7561 tatattacag tttgaatact tgaaatttta actctcctta ccgcttgtgc cataaacatt
     7621 agcttattaa caggagcttt gtcgtgcact tctgccccga ctataataat gttctcatta
     7681 tagctaacta tatgattaat actaggtctt ccaggtaaat aattacctat gctatttccg
     7741 gttcccattt gaaattattt ttttaggact atttaaaatt aattttcctt ctgttgcttc
     7801 caaccacttg gattcggaga tttcaatcat tttttttcca ctaataagaa tatctttttc
     7861 agtggttttt ataatcatat tttttgcaaa ttttattata gccataacta gtaaagatta
     7921 gatttttcac cactattcca ttcaatggtc ttagctcctt gtattgtaat attttcttct
     7981 gtggttgtaa tacctattgc accagaaaag gtttcagctt tttttgcttg tcttagtgca
     8041 atgtcgtcag ctatttcagt tctactattg gatatctcca ttcggtttcc tgttgctgtt
     8101 tcagaaatat cattaccagc agaaattgtg atgttttgtg taacagatgt tatttgattt
     8161 tttccaatag ttgttgtcat attttttcca acgtttatac tcatattctc tccaacatta
     8221 aaagtcatat tcttaggcgc agtcaccata atatttccct gtccatccat aaaataagta
     8281 ttaccacttg gatcaataat atttacacta ccctcagcat cattcatcaa aatacggatt
     8341 ccgcttctgg tttgaataga tttaaggtga ttattgactc cacctcctaa tgcaacattt
     8401 ccatggaaca ttccgcccat ggcaaaaggg aaatcaggat tgtgatattc aaaacctacc
     8461 ataacctggt ctccaatttc aggaatggct acaaatcctc tattctgact tatagcatct
     8521 gttcctcccg catcaggact catcattctg ataaagcttg tggtatcatt taattgccaa
     8581 tcaaattgta cttgtattct tccttggttt aaaggatcaa cattcgatat aacagttgct
     8641 acttgcggtt ctgctttagg tatttcaaaa ttaggcttag gcataaaacc tgttccttca
     8701 gctattgctt caaaacttcc tctataataa cctctggcat cgacttcgtg acttacttct
     8761 ataatcatta aagtagtaaa atgtgaggtt tgattactgt ctggctttct catagctaag
     8821 tcagcaacac aaccaatata tagaaacgga actgttgttt ctcttgaaac tgtaaaaaca
     8881 tctacagcct tacttcctct tgcactcttt tgggaatcat ctacatcacg aaacatattg
     8941 gcattaatgg gagtaggtgt tagtgaacgg gttttaaaga tattatcatt caattcataa
     9001 gctttggctg ataactcacc taaatgctta atacgattgt caacacctaa catttttgta
     9061 tgactactac tattgtaacc aaagtattca ggttttgtat gtactgcctt aagttctatg
     9121 gtaacatcat ttacgttact gccatcaata agcttaatag acttttcatt aggtggaagt
     9181 tttccaaaat gtagaacttc tccatcataa taaaattgct ctccgtaagc ttctgcaatt
     9241 ctggcaaggt agttataatg agtttcacaa tactgtgcgc tatagttgat gtagctatta
     9301 ttttgagtat ctaccctaaa atcaaaatca tttgtaccca atgcttcctt gataaccctg
     9361 tctgcaataa tggaagtatt tacagattga cctcctccaa aactttgtgt gtgtggagca
     9421 gagtccatca gaatggttgg gctgtaacct ttgagtacaa tatttcccaa actcattttt
     9481 tccttgctga atgatacatt tgtaatgatt cctacaaatg ttctctctgg gttttcatgc
     9541 tctggatctt tgtatttgaa tgtaacagtc aatcgttttc ccatgaactg tctagcttgt
     9601 tcaagattgt agttttgaat ttcattcaaa gaatcatgag ccagaataag ttcaaaacta
     9661 tgatgggttt ttgcgctttg ttgtaaacgg aaatgtttaa aatgatgaat aggttttcca
     9721 ccagctacaa tatcgagctg aatgacacga ttgatgccag aaatatggtt ttcagaaatc
     9781 ttctctgaat ttgagatatt tttttcatag gattatgtgt gttttttatt atatcaccaa
     9841 atgtagataa aaacaatgcc aaaatagatt ttttgtaaca caattttaaa aattgtagta
     9901 gttctacgat cttaatttca aaaactttgt ccatttgcac aaagtttttt gttttataaa
     9961 gccccgaaaa atcgtatttt tgttcaaatt ataagatttt atggaatttt tagacagata
    10021 ccagcagatt gttggggacg ccatcaataa atatactttt aaagataaac ctacggagct
    10081 gtatgagccg atgaactata ttatttccca tggtggaaaa cgtcttcgtc ccattatggt
    10141 gctgatggct tgtgatctgt tcggtggaga cctgaagcag gctataaaac cagctttagc
    10201 aatcgagttt ttccataatt tcaccctgat ccatgatgat attatggatg aagctccttt
    10261 aagaagaaat aaacctacga tccacacttt gcatgggatc aatgtgggga ttctttcagg
    10321 agatggatta atgcttaaag cctataaatt ctttgaagat cttgaacctg aaatcttcaa
    10381 ggcttgtatc agaatattta cccatacagg gcttctttta tgtgaaggac agcaatatga
    10441 tattaatttt gaaactcagg agaatgttac ttttgatgat tacatcagaa tgattactta
    10501 taaaaccgga gtattgagtg cttcttcttt tgagattgga gctttgattg caaaagctga
    10561 ttttaaagac gcaaaagcga tctttaactt cggaaaacac atcggaattg catttcaaat
    10621 catggatgat tatcttgacg tattcggaga tcaggcacag tttgggaaaa aacatgccgg
    10681 agatatctac gaaaacaaga aaacagttct ttacctgtta gcaagagaac atgctacaga
    10741 agaagaaaga aaggaactgg attactggta ttctaagaaa acagataata ttgataagat
    10801 ctatggcgtt gaaaagatct tcagaagaac caaagtggat gagaaagccc ttcgtctgat
    10861 tgaaaagcac aacgaaatcg gtcagagcta tctgcagaaa attgatattc ctgaagagaa
    10921 gaaaaagccg ttcattgagt tggcaaatta tcttttaaga agagaaagct aacatgatta
    10981 ttgggcatta tgtaatccgt acctatcgga aatttaaaaa tcaggggctg ggaaccagat
    11041 ttgtgattgt gggaatacca ttaatcccgg tacagagttt ttatattttt aaagatactg
    11101 gccgaacaat ggaagtggat ctatactgga aacaggctgt gaaagtttat ttgattatga
    11161 tttcggtatt ttatctgttc ataaaatatc tgaaagggtc aagttataat gaaatgcctt
    11221 ttgaaaagct gtttttgatt gtattgacta ttaatgcgct ggtgtacttt ttatttgatc
    11281 cttatacaag gaaagacagg cagataagag aattactaag cagatcagta tatattaatg
    11341 cacttccgaa attcctggga cagactgctg catacaatgt tcaatccggt ttcattcgta
    11401 ccttcagaga aaactttggt ggtgcaaact ggaaagatat gatgaaaagc ggagcgtata
    11461 ctgatcagca cattccgttt ctgtttccga ttattttgta tgatctgtat ttgtatgaaa
    11521 acgaagtgac aaaaagatat tttgacactg tttttaaaag atacaaggaa cttgaaaata
    11581 tctagatttg aaaaaagaaa acaaaatata gatgaagaat aggttgcgga taacaatagt
    11641 ttgcctgcaa cctattattt attaccagag acctgtacaa tgaaattcag aacagaagtt
    11701 gatattccta aatcagaaaa aaaaatagag attgaagatc ggatattttc aatcggttcc
    11761 tgttttgcct ctgaaatgac cgaattgctg aaagatggtc agcttcagac cctcaataat
    11821 ccttttggaa caatttttaa tcctttttcc attaataatg cggtaaaaag acttcatgat
    11881 tcggaatttt atatcgaaga tgaactcatt atctataatg aagaatatat ctctttagat
    11941 catcatacaa gctttgatac aaggtatatt catcagactt tagacaagat caatggagct
    12001 attgaaatag gcaatgcctt tcttcaggaa gcagactgga ttattattac ctatgggtct
    12061 tctttcatct atgaatttct tccgaaacaa aaactggtgg ccaactgtca taagatccca
    12121 cagaaattct ttgagaagag gctgctaacg catcaggagc ttacaggttc tatttataat
    12181 actatcctgg aacttaagga tatttgtaaa gaaggcgttc agattttatt ttctgtttct
    12241 ccggtaagac acaccaaaga tggtatggtg gagaatcagt tgagcaaatc caagttaatt
    12301 acggccattc atgagtctat ttctctgttt gaagactgtc attatttacc ggtttacgaa
    12361 attttgatgg atgatctgag agattatcgt ttttataaag aagatatgat tcatccaagt
    12421 actcaggctg ttaattatat ttttgataag tttggagact cttatttttc agatgatacc
    12481 aaagacttta ttaaagaaaa ttttaaaata atgagggcgt tggagcatag aactaacgat
    12541 gtaaaagacc ctaaatttat agagttccgg gaaaagctgg atcagagaat agaaaatcaa
    12601 cgtaaaaaag taaaacacac catattcaaa tgattgattt cacaaagatt gactatttga
    12661 aaacaggcaa tgagaaacaa agaaaagctt atgcacttct tgcaaagcat cgtatttttg
    12721 aaaaactaaa agagtattca ccaactttag caggaactgt tcctattgga attgatatag
    12781 aaggtagtga tcttgacctc atttttgagg tggacttaag atttgagaaa gactttttag
    12841 aggatttaat gggtagcaga tttattcccc atgatgtaag agtagaatat cccattgtaa
    12901 atggagaaag gtgcattaca ttaaatttta tactggaagg agtccccatt gagattttcg
    12961 gacagaataa acctacaatt cagcaaaacg cttaccgcca catgattgct gaacataaaa
    13021 tattagaaga aaaaggagaa gaatttaaac agaaaataat agaacttaaa aaacagggta
    13081 taaagacaga accagctttc ggaatattgc tgggccttga aaacccttac gaagatctat
    13141 tgaaatttta ataaaatgat tgacacacat acccatttat acgcagaaga atttgatcaa
    13201 gacaggaaag agactattca aagagcttta gataaaggaa ttacagagtt ttaccttccg
    13261 gctattgatt ccgagtctca tgagaaaatg ctacagctgg atgttgaata tcctggaaag
    13321 attttttcaa tgatggggct tcacccttgc tacgtaaaac ctgaatcctg ggaaaaagaa
    13381 ttggagattg ttaagaatta tcttgaccaa agacatttcc ctgcgatagg agagatcgga
    13441 attgatttgt attgggataa aacaactttg gatattcagg taaaagcttt tgaacagcag
    13501 atcgattggg ccatagaaaa agaccttcct attgtgattc atacaagaga aagctttgat
    13561 gaaacgttcg aagtgttaga aagaaagaaa cattccaaat taagagggat tttccattgt
    13621 ttttccggaa atctggaaca ggctcagcat gcgattgacc tgaatttcat tttaggaata
    13681 gggggagtag tgacctttaa aaatgggaaa attgaccagt ttttgaatga agttccttta
    13741 gataaaatcg tattggaaac cgattctcct tacttagctc cggttccgca cagaggaaaa
    13801 agaaacgaga gcgcatacct tgatctcgta gctgggaaac tagtgaatat ttatggtaaa
    13861 gatttctctg agatagacag aattacaact gaaaatgcca agaaaatgtt tattaatagt
    13921 tgaaatatat ggaaagacta ttaaccccaa aattgaataa aacaatttca gctgttgtat
    13981 tcacccttta tactttaatc aatctttcgt ttcttgtcaa gtatggagta aggcagtctg
    14041 ttattccaat ttatcttctg gtggttgtat ttattatagt acattttttt atctttaaat
    14101 acagtggccg tatattttca aagctaacag aaaaaccttt tattttaaag gcttttattg
    14161 ttgttattac attagcttat atgggcctgg cacacgtcct taaagatcct tacaaactca
    14221 atattgatcg atggcagacc ttagagtatt cactcagata ttggcttgag gggaaatata
    14281 tttacgatac aaaaaacttt gttggaaact atccttctta tcttccgggg cagcttctga
    14341 tagctgtaat tttccttttt ttaggaaatg ttggttatct tcaggttgcg gcttttattt
    14401 tattctgcta tgctgttata aaagaattta aaagtaaaga aattcaatta ttaggaatat
    14461 ttcttctggg gatttcatta tcttatatct atgaggtgat ctgcaaaagc gatcttattt
    14521 cttcctttat tgtagtttca gcatttatct tatattggca tagaaagttt gagaaagatt
    14581 attttaagaa ctctttttta ctggggattt tgttgggttt tatctgcctc acaagaagtg
    14641 tggtgatcat tccgctaatc ttattcttta tgaagccatt tttggcaaca cagatgagta
    14701 ataaagtaaa aacaggggcg gggttcatta ttactttttc tttactactg gcaacagtac
    14761 tgcttcctgc aaaagatttt gattatattt taaagtataa tccattacaa ttacaaggac
    14821 aggctaataa atatgttacc ttatttttcc tgatgattac cgtgattctg tccttttatg
    14881 ttaggaatat aaagcaggta ttttatttag cgtcagtgat tatttttaca atgatgggat
    14941 cttacattgt agagaccatt atgttaggct ggacatttga ttatatgaat gtttcttacc
    15001 tggctacagc attgcctttc tgtattatag ggtattgtta ttccagacaa gaaaaaagta
    15061 caattgaaca tatagagtaa aataaaagtc cctgtcattt ttgaaaggga ctcttattta
    15121 tttttttctg gtgaaattct tattcttagg ttttttgaat ccggtagaag gagtttctga
    15181 cggtttcggt ttccttttat ttctattatt aggccttgaa ttgttattcg gtttttgtga
    15241 tctttctcca cctgctggaa caggtttatt attagaatct cttttttgtg ctacaagatc
    15301 atccgtatgg aacggatggt ttttaataac aggaattttc tttccgatca gcttttctgt
    15361 atttttcaga ttaagaagat ccaatccatc tacaaaagaa atagaagttc cttctgctcc
    15421 cgctcttcct gttctaccga ttctgtgtac ataggtttca gaaacatcag acagttcaaa
    15481 attaatgaca aatttcagtt catcaatatc aatccctctc gcggcaatat cagtagctac
    15541 cagaaccctt gttttccctg atttgaagtt attaagcgca ttttgtcttg cattttgtga
    15601 tttgtttcca tgaatagctt cgacagaaat ctcatccttc tgaagttttc ttgcgatttt
    15661 atcagctccg tgctttgttc tggaaaatac cagtacagaa tctgcaatat cattttgaag
    15721 gatgtgagat aaaagattta acttgttttc tttttctaca aaataaacag attgttttat
    15781 ggtatctgct gtagaggaaa ccggagtaac ttctactttt acagggttat tcaggataga
    15841 atttgccagt ttctggattt ctcccggcat cgttgcagag aagaataaag tctgtctttt
    15901 ttgaggtaat agtttgatga ttcttttcac atcatgtaca aatcccatat caagcattct
    15961 gtccgcttca tcaagaacaa atatttcaag attttttaag ctgataatcc cttgtgcaat
    16021 gaagtcaaga agtcttcctg gtgtagccac cagaatgtct accccttttt ttaaggcagc
    16081 ttcctgattt ccttgtttaa ctccaccaaa gataacaagc tcttttaggg gtagatattt
    16141 accgtaagcc tgaatgtttt cctcaatctg gatcgccagt tctctggttg gcgtaaggat
    16201 taaggcttta atatttttgt tcggtatttt atttttagat agattctgta gaataggaat
    16261 agcaaaagca gctgttttcc ctgttcctgt ctgtgcgcag cctaaaaagt ctctgccttg
    16321 taaaatttca ggaatagatc tttcctgaat gggtgttgga gtggtatatc cctgttcctg
    16381 aattgccttg gcaataggtt ctattaagtt taagtctgta aaattcaaat gaattatttt
    16441 aaaatttaaa taaaaattcc ctctgtctga aaagaattac atcctgcaaa ggtaggttaa
    16501 aaatttaaga atttgatttt aagcttcaag aacctgtttt ttggaggagt ttggtttatt
    16561 gataggtaaa aaaagactgc tcccaaatgg aaacagccat atattatcga aaatgtaagt
    16621 tttatttaaa acgatatcca acaccagctt gtaaaaagcc aatttttgta ggaacagcat
    16681 tacttttatt catttcaaag aaattgaaat tgtatcgggc atccacaaag aacttttcag
    16741 taattttata ttctgcacca aggaaaggga agaggtttac tgtttttaag ccctcagatt
    16801 ctccggtatc ctcgccaaac atagtactaa tttttgtttt tgatgaaata ttaaatccga
    16861 tattcattcc cacagaagca gaaaattttg gtataaaata atattttgca gaaataggaa
    16921 cctgtatctg attaatttta taatcaaatt tcatgttacc tacatctaca atttcattac
    16981 ctattagttg agtccaggga tatgaagtac tgccacctag ttgagtatat aatacctctg
    17041 cctgtacact gaattgggac gaaataggtt tttcagcaac tatgcctgca tagaaatacg
    17101 attttgagtc cattttttct ccgtaaaatt tcatgctgga taaggaatag cctcctttta
    17161 ctccaaagct tatttctgaa ttttgcgcac tgacaagagt tgaaatgata aataatagaa
    17221 cgagtgaaat gttctttttc atggttgttt tgaggtaaat aatcgtagtt tttataaact
    17281 ataattccct ctttaacaga aggaattatg atgtacaaat ataatttaat ttttttagtc
    17341 cattttttta atcttcaatt aaataattat atatttcatt gagccatttc aaaacatctt
    17401 cattatagat aaaatatctt ttactcttct agatcagttg actcttataa gctaaattaa
    17461 gcctcaaaat accattctaa gaaatcatta aatgattccc acttttcaat aacaaccatt
    17521 ccattttcag agtaaccaat tatttcgaca ctatttttct ctttattata aaaataggcc
    17581 ctttccccct caaattctga aattacataa taattatcat ttaaattcaa atctcttctt
    17641 aaactattat taataactct gtaatcacta ttttcataca tccagcatat ttgccataat
    17701 tcaaattttt tcgaataaaa acctcctgga ttttcctctg catgtgtata gaaaacgcca
    17761 aaatcagagc tagtgtccaa atttaaatct ttcagaatct ctctatacct ttcacagtcg
    17821 atatctacat cttcaaacca agcatctttt tgcttcaaat aattaatcac tttcaaactt
    17881 aacataatct catctttata aaggacagct actattagta ttctatttta aaatattttg
    17941 gatttacttt ctgagaatta cagaaaaata aaaatataaa agtacaggct tagtacatat
    18001 tttatagttg gcaatttctt tatctgctct caataactgt tccaatgtaa agcagaagaa
    18061 acgaaaattg atgtctaact gaatagtcta tggaataaaa aaataaagag gaacattgtt
    18121 gttcctcttt atgtatattt taaaaatcaa attctcaaat ctgagactat ccatgaagtt
    18181 gtttccagat agcatccttc agctctacga gaccttctcc ggtaactcct gaaaagaata
    18241 aaggttgctt attctccggg aattcagcag aaatttcttt tttcagttca tcatccaaaa
    18301 gatcagattt tgaaacggaa ataatgaagt ctttgtctaa aagttcagga ttatattcct
    18361 ttaattcatt ttccagaatt ttaaactcct ggaagtggtt ttcagaatct gcaggaatta
    18421 aaaataaaag gatcgagttt ctttcaatat gtctcaggaa tctgtgtcct aatccttttc
    18481 cttctgctgc tccttcaata atccctggaa tatcagccat tacaaatgat ttgtaatttc
    18541 tgtaatccac gattcctaag ttaggagtca gggttgtaaa ggcatagttg gcaattttag
    18601 gttttgctgc agatacagaa gcaagaagtg tagattttcc ggcattcgga aacccaacca
    18661 atcctacatc agctaaaatt tttagctcga aaacaatata gccttcctgg ccttccattc
    18721 cgggctgagc atatcttgga gtctgattgg tagaagattt gaagaattcg tttcctcttc
    18781 ctccttttcc tccttccatc aaaatgattt cctgcttgtc ttcaagaatc tcaccgataa
    18841 tttctccttc ttcattttta gcgattgttc cgatgggaac atcaatataa atatcagaac
    18901 cgtcagcacc ggtaagctgg tttttggctc cgttttcacc acgctcagct ttaatatggc
    18961 gggtgtatcg aagcggaagt aaagtccatt cctgagcatt tcctctcata ataacgtggc
    19021 caccacgacc tccgtcacct ccatcaggac ctcctttagg aatatacttt tcacggcgaa
    19081 ggtgggcaga accagcacct ccgtgtccgc ttttacaatg gatctttacg taatctacaa
    19141 agttagacat atagtatgtg ttacgagttg cgagctacgg gacgaaaata cgaatcccgt
    19201 atcccgaatc tcgattattt aattttttct acttcagcaa aaagtttctg agcaatttca
    19261 tcaatttctc ctacaccgtt tacttcaaca tatttcccct gttgcttgta aagctcggct
    19321 acttctgctg ttttagtata atattcttta attctgtttt cgatgatctc tacattgctg
    19381 tcgtctgatc taccgctggt ttctcctctt ttcagaagtc tttctaccaa aattttatct
    19441 tctacgatca atgaaagaca aatgtcaatc tcgtcattta gttcttcttt aacgattttt
    19501 tccaaagctt ctgtctgagc agtcgttctt ggatatccat caaagataaa accattggta
    19561 ttggtaggtt ttctgatctc gtcaatcagc atatctgttg ttacctgatc cggaaccaat
    19621 tctcctttat cgatgtaaga cttagccagt tttccaagtt cagtgtcatt tttcatgtta
    19681 tatctgaaaa gatcacctgt tgaaacctgc tttaaattga atttctcgat tagattctga
    19741 gcttgtgttc cttttccact tcctggaggg ccgaacagaa ctatgtttat cataatgttg
    19801 tttcgcttcc ggcaatgagc aactgcttct tgcttttagc tttatttagt taatatttta
    19861 ctttatttcg attgaatatt taaagctaaa agccagtagc taatagctat aggcatttaa
    19921 tgattgattt gtccttcttc taattggtac aagttaggta ggtttcttcc caattcatca
    19981 taatccaatc cataaccaag aacaaattta tttggaattt cctttccaat ataatccagt
    20041 ttgaagtcct ttttataaat ctcaggtttc aataagaaac ttgccagttt tacagattta
    20101 ggacgttgtg tttcctggaa atatttgaaa agactttcaa cggtatttcc tgtatcaaca
    20161 atgtcttcta caagaataat gtgacggtct tttacatctt ttgtcagttc cattttctgg
    20221 taaacaatcc ctgtagattc agttcctaca taagaactca tttgaaggaa agcgatttcg
    20281 cattccccag gataatattt taaaagatct gagaagaaca tgataactcc attcaaaaca
    20341 ccaatgaaaa caggaacttc atctttgtaa tcttcataaa ttcttaatgc tgtctctttt
    20401 acaatttcct gaatttcggc atcctttaaa taaggaacga aagttttgtc gtgaacttta
    20461 atactttcca taaaaaattt tagtaggagg caaagttacg gatttttgat ttttcattaa
    20521 aatctttttg tgtttaatca cggatttatc ctatatttgt tctttcaaaa cccataaata
    20581 cagacatgta ggatataatt tctttcagat tcaatgaagc ggtaaccaat gagttgccgg
    20641 tgtttaacct ttattaagaa agaaatcatg attttactgc acaatatatc ctttgggttt
    20701 ccgggaggag acctcctttt caattctatc aatttaacaa taccatccca taccaaatca
    20761 gctttggtag gaagtaatgg catggggaaa tctaccctgc tgaagatcat agcgaacgaa
    20821 ataaagccac tggaaggaac ggtaaacatc cagggtggaa ttttctatgt tccacaaatg
    20881 tttggaaatt ttaatcattt aaccatcgca gagtgcctga atatagacca aaagcttttg
    20941 gcccttgaaa aaattacgag tggggaagtg ga
//
