LOCUS       NZ_CP120209            33918 bp    DNA     circular CON 19-MAY-2024
DEFINITION  Chryseobacterium indologenes strain Ery-6B chromosome, complete
            genome.
ACCESSION   NZ_CP120209
VERSION     NZ_CP120209.1
KEYWORDS    RefSeq.
SOURCE      Chryseobacterium indologenes
  ORGANISM  Chryseobacterium indologenes
            Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
            Weeksellaceae; Chryseobacterium group; Chryseobacterium.
REFERENCE   1  (bases 1 to 5246911)
  AUTHORS   Xu,S.
  TITLE     Synergistic degradation of erythromycin by symbiotic bacteria Ery-6A
            and Ery-6B and application in simulated water remediation
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5246911)
  AUTHORS   Xu,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-FEB-2023) Zhejiang Agriculture and Forestry
            University, School of Environment and Resources, East Lake Campus of
            Zhejiang A&F University, Hangzhou City, Zhejiang Province, Hangzhou
            311300, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. DEC-2022
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: HiFiasm/Unicycler/Flye
            Genome Coverage                   :: 181.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_029339075.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 05:09:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,739
            CDSs (total)                      :: 4,629
            Genes (coding)                    :: 4,609
            CDSs (with protein)               :: 4,609
            Genes (RNA)                       :: 110
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 20
            CDSs (without protein)            :: 20
            Pseudo Genes (ambiguous residues) :: 0 of 20
            Pseudo Genes (frameshifted)       :: 8 of 20
            Pseudo Genes (incomplete)         :: 12 of 20
            Pseudo Genes (internal stop)      :: 4 of 20
            Pseudo Genes (multiple problems)  :: 3 of 20
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:37:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2471597
            Orig. end                         :: 2505515
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP120209.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..33918
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NAPAA"
                     /region_number="6"
                     /rules="(AMP-binding and TIGR02353)"
                     /tool="antismash"
     cand_cluster    1..33918
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(AMP-binding and TIGR02353)"
                     /kind="single"
                     /product="NAPAA"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..33918
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[15000:18918](+)"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      15001..18918
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
     gene            complement(484..1029)
                     /locus_tag="PYS58_RS11365"
                     /old_locus_tag="PYS58_11365"
     CDS             complement(484..1029)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002976823.1"
                     /locus_tag="PYS58_RS11365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11365"
                     /product="hypothetical protein"
                     /protein_id="WP_185247801.1"
                     /transl_table=11
                     /translation="MLKIEELVHAYIHTHCDFEKELVLTNYFQADWEADILIIDAGGRS
                     HEIEIKLSKSDFKNDFKKSYINKDTGEKFLKHDKISCGDYVCNAFSFLLPMGMVDSESI
                     PEHCGIIEFYHNADTWDTEFYLIRPPKRLHGDSYWKLNDKDLFIRKMALNLLQRKMEIK
                     GKHEELIFKNPFDLKNKK"
     gene            complement(1097..2089)
                     /locus_tag="PYS58_RS11370"
                     /old_locus_tag="PYS58_11370"
     CDS             complement(1097..2089)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009087911.1"
                     /locus_tag="PYS58_RS11370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11370"
                     /product="acyl transferase"
                     /protein_id="WP_185247800.1"
                     /transl_table=11
                     /translation="MEPKNIFNIKTEQDFLNASLKTFRYQYENVEIYRKFVDFLNISPD
                     EVDDVSKIPFLPIEMFKNHQILDGNATTDLFFQSSGTTQMNLSKHFIADTDLYEESIYK
                     SFEQFIGKPEDFIFLGLLPSYLERQNSSLIYMVDYLMKKSAKAENGYFLYNHSDLFDLL
                     NQLQDKKVILFGVSFALLDFLDYCHSERSEESLSVLENLVVIETGGMKGRKEEMTKDEL
                     LKILQEGFNTDTIYSEYSMTELLSQAYSLGNNEYQCPNWMQIKIRNVEDPLSYEKDGRT
                     GAINIIDLANTYSCSFIATQDLGKVVGDKFQVLGRIDHSDIRGCSLLVS"
     gene            complement(2285..3055)
                     /locus_tag="PYS58_RS11375"
                     /old_locus_tag="PYS58_11375"
     CDS             complement(2285..3055)
                     /EC_number="3.6.1.54"
                     /GO_function="GO:0008758 - UDP-2,3-diacylglucosamine
                     hydrolase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002976818.1"
                     /locus_tag="PYS58_RS11375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11375"
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /protein_id="WP_185247799.1"
                     /transl_table=11
                     /translation="MLKTIINLEPGKKVYFASDQHFGAPTPKESKVREERFIRWMDQIK
                     EDAQVLFLMGDLFDFWHEWKHVVPKGYIRVLGKIAELKDRGIHIYFFVGNHDLWMKDYL
                     EEEIGCTVFYQKQYFEMGGKQFLLAHGDGLGPGDKGYKRMKRVFTNPVAQWFFKWLHPD
                     IAMKIALYLSQKNKMISGEEDKAFLGEDKEFLIIYSKEKLRTQKIDYFVYGHRHLPMVL
                     DLGQNSKYINLGDWISYFTYGVFEKDFELKTFEK"
     gene            complement(3079..3525)
                     /locus_tag="PYS58_RS11380"
                     /old_locus_tag="PYS58_11380"
     CDS             complement(3079..3525)
                     /EC_number="4.1.2.50"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070497 -
                     6-carboxy-5,6,7,8-tetrahydropterin synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTPS"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002976816.1"
                     /locus_tag="PYS58_RS11380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11380"
                     /product="6-carboxytetrahydropterin synthase"
                     /protein_id="WP_045500594.1"
                     /sec_met_domain="PTPS (E-value: 1.5e-30, bitscore: 103.8,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRITKIFTFETAHVLYNYDGKCKNMHGHSYKLFVTVKGKPINDI
                     DNPKNGMVVDFGDIKSIVKSEIVDVWDHAVLLNALTPHKELGDDLEQKGHKVIYCSFQP
                     TCENMLYAIAAKIKSRLPEGISLAYLKLHETENSYGEWFAEDNQ"
     misc_feature    complement(3537..3552)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.12"
                     /tool="antismash"
     gene            complement(3618..4880)
                     /locus_tag="PYS58_RS11385"
                     /old_locus_tag="PYS58_11385"
     CDS             complement(3618..4880)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016994.4"
                     /locus_tag="PYS58_RS11385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11385"
                     /product="erythromycin esterase family protein"
                     /protein_id="WP_276285397.1"
                     /transl_table=11
                     /translation="MLNNKSLTFAFLLFFSIGFSQNAQNVTQIPKTFADHKNMTKAVKG
                     ISEQLKAHTIVGLGEGTHGTKEFNEIRSEISKQLISKNEFRIVAFESAYGDASLLNEAV
                     NSDVDLNIAIKKYITSIWQTKEIYNLLIWIREYNKNHKDKVIISGFDTDVLTHSAEILK
                     KKGDLGKEYTEITNEIGKKATLQDEMWEKQNDPSFKLDMNVVIKNGTEGFLLTKKLDSL
                     FGQKIDVNSKLALYHLEQGFKIPYEASKKNYDVSRDLIMAEMIETIQSGYNKKMILFAH
                     NGHIALKPIIVDGMGGYLKKKYGNKYYALATSTVFGSYSATTDPRAVKNNKYSSYQLPK
                     QLENSWEEKLGNNKYENYFVDFNGVSENVYGQSFKMRLLGYGPVTPPTEKFTITEPLKL
                     NECFNGIIFIKQTNPSEHLSN"
     gene            complement(4902..6347)
                     /locus_tag="PYS58_RS11390"
                     /old_locus_tag="PYS58_11390"
     CDS             complement(4902..6347)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012371.4"
                     /locus_tag="PYS58_RS11390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11390"
                     /product="serine hydrolase"
                     /protein_id="WP_276285398.1"
                     /sec_met_domain="CBM_48 (E-value: 3e-05, bitscore: 22.3,
                     seeds: 59, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHSILAALFFNVSILGFSQTVEQSKAIDSYIKNVIQINEIPGMA
                     VGIVKNDKVTFQQYYGREDLESDKKVNPNSMFRVYSTTKLMANVGLFKLIEEGKVSLDD
                     KISKYVDNLPKDWQNIQVKNIVSHSSGLPDMLDVKDLSEKATHKEAIDRLSKEKIEFEA
                     GDHYRYNQTNYLLITMIIEKITGKTFEEYILENQFPDSKNQVVFSSNSIEKIPNRIVKY
                     DYKPEKKRYEKSTVIHGLRFHSANGLAVTLPAFLQWSIHFSKNDFLKPETQKMMWKPFD
                     YKNNDWEFGHGWEITDNNKTKSYGFSGGNVSAYSIFPDNNMAIVVMYNGNKGFPVMYQM
                     VNHIAGIIDKNLMEPYMLAEEITIAEPFAHPNLKKKVYGYRIENDKVIFSYQYPEKLST
                     EFIKSVSVAGVFNNWNPGDPSYQMIPKKNNVFELTVPKSQFEKGKTYGFKFVMNNRTGW
                     LTVPYNAANTDGTRDNNLTLKIN"
     gene            complement(6439..6822)
                     /locus_tag="PYS58_RS11395"
                     /old_locus_tag="PYS58_11395"
     CDS             complement(6439..6822)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002677468.1"
                     /locus_tag="PYS58_RS11395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11395"
                     /product="hypothetical protein"
                     /protein_id="WP_185247796.1"
                     /transl_table=11
                     /translation="MKNKLRKITVEHEKYLYLVTDKYHPGAETNTLTVKIFLSGEKQTP
                     LIIDFLTFEHYFMGQPLKSGISLMNVVTDSLENVNINEPKYIQKLIVKGIEKGWNGKNK
                     MEKQNGLDYLSELGYEIDSLKPK"
     gene            complement(6812..7213)
                     /locus_tag="PYS58_RS11400"
                     /old_locus_tag="PYS58_11400"
     CDS             complement(6812..7213)
                     /GO_function="GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007845784.1"
                     /locus_tag="PYS58_RS11400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11400"
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="WP_185247795.1"
                     /sec_met_domain="4HBT_2 (E-value: 3.1e-09, bitscore: 35.4,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLVYEKQIKVTEEHIDQNNHVNNVQYVHWVEEVAAEHWNLLKNK
                     TEYENDVWMLLDHHIRYKKQVYLNDVITVKTYPQEPEGAKQPRKVEFYCHDELVVDSST
                     LWILFDTEAKKIKRLESNWLEKLEKQIEE"
     misc_feature    7323..7335
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     misc_feature    complement(7330..7342)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     gene            complement(7353..7928)
                     /locus_tag="PYS58_RS11405"
                     /old_locus_tag="PYS58_11405"
     CDS             complement(7353..7928)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002976808.1"
                     /locus_tag="PYS58_RS11405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11405"
                     /product="OmpH family outer membrane protein"
                     /protein_id="WP_185247794.1"
                     /transl_table=11
                     /translation="MKLIKLFFIAAGLTLTANAANAQQKIGSVNTADIFDSMTEVKTAG
                     EAIDNLTKTKQTEIDKLINEYQTKLKVAQDKEKTFNETNKEALTKELIAAQTELDALGK
                     KIEEARAQAAKEISAKQGELFTPIQQKIKTAIFAVSKERNLSFVFDIATQGSNLVYTDE
                     SEDITAQVKTKLGASATASKPAAGKAKK"
     misc_feature    complement(7941..7954)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.91"
                     /tool="antismash"
     gene            complement(8156..9439)
                     /gene="aceA"
                     /locus_tag="PYS58_RS11410"
                     /old_locus_tag="PYS58_11410"
     CDS             complement(8156..9439)
                     /EC_number="4.1.3.1"
                     /GO_function="GO:0004451 - isocitrate lyase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aceA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002554010.1"
                     /locus_tag="PYS58_RS11410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11410"
                     /product="isocitrate lyase"
                     /protein_id="WP_346429909.1"
                     /sec_met_domain="PEP_mutase (E-value: 6.3e-17, bitscore:
                     60.0, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKTKQEQIQALEQDWLTNPRWNGVKRPYTAEEVLRLRGSYTIDY
                     TIATEMAKKFWEKLNTQDYVAGLGALTGNQAVQEVDAGLEAIYLSGWQVAADANLSGEM
                     YPDQSLYPANSVPSVVKKINNALLRADQVQSVSGTGDKEYLVPIIADAEAGFGGNLNAF
                     ELMKQMIEAGAAGVHFEDQLSSAKKCGHLGGKVLVPTQEAINKLIAARLAADVLGVPSL
                     IIARTDADAADLLTSDIDDRDKKFVTGERTSEGFYVVRNGVEQGIDRGLSYAPYADLIW
                     METSNPDLEQAKRFADGIHSKFPGKMLAYNCSPSFNWAAKLSVEEMSTFREELAKMGYK
                     FQFITLAGFHALNTAMFELALAYKEKGMAGYSELQEREFALQQKGFRAVKHQSFVGTGY
                     FDEVQNIVTNGSSATVAMKDSTETAQFH"
     gene            complement(9522..11096)
                     /gene="aceB"
                     /locus_tag="PYS58_RS11415"
                     /old_locus_tag="PYS58_11415"
     CDS             complement(9522..11096)
                     /EC_number="2.3.3.9"
                     /GO_function="GO:0004474 - malate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aceB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007845786.1"
                     /locus_tag="PYS58_RS11415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11415"
                     /product="malate synthase A"
                     /protein_id="WP_276285400.1"
                     /transl_table=11
                     /translation="METKTQLKITAQKQFEEIFTPDLIDFLMALHQNFNHKRLELLEER
                     KKTQKEFDQGNLPKFLKETEEVRNGNWVCAPLPEDLLDRRVEITGPVDRKMIINALNSG
                     AFTFMADFEDSSSPTWENGMEGQINLSDAINRTIDFVNEAGKAYQLNEKTAVLLVRPRG
                     LHLPEKHIKINDEETSGSLTDFGIYFFRNAKNLLEKGSGPYFYLPKLEHYKEARWWNEV
                     FVFAQEYLGIPQGTIKATVLIETITASFQIDEILYELKEHSSGLNCGRWDYIFSYIKKF
                     RNLPEFMVPDRDQVTMTSPFMSAYSKRVIEGCHKRNVHAMGGMAAQIPVKNDDKANTIA
                     FEKVRSDKEREVKNGHDGTWVAHPALVSLAKDVFDEYMPSKNQIDKKLEYNIQESELLE
                     IPKGEITEKGVRKNINVGILYLESWLMGVGAAAIYNLMEDAATAEISRTQIWQWLKNEA
                     VLSDDRTLTRNMVLQWESEEMDNIEKYVGEVRFKKGKFNLAKELFNELIFSENFEEFLT
                     LKAYPFI"
     gene            11223..12695
                     /locus_tag="PYS58_RS11420"
                     /old_locus_tag="PYS58_11420"
     CDS             11223..12695
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012782268.1"
                     /locus_tag="PYS58_RS11420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11420"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_276285401.1"
                     /transl_table=11
                     /translation="MNSESDFIKTVFGLKLKQQRQKKNWSLQDLAVKTGLSKSYLNEIE
                     NGKKYPKHDKIIQLSDALNCTFDDLVSTKLDKSLAPFNEILQSDFFKEVPLELFGINKN
                     NLISIISDAPKKVTAFINALIEISQNYNLGKERFYFAVLRSFQELYDNYFPEIEDKVSL
                     FTEENHLQIDKDLKADILETILSEKFGYTIQWESFEKYGTLDNLRSLFFPEKKLLLLNK
                     KLEKDQKTFILAKEIGFNVLELKVRPTTYSWLDFGSFEEILNNFYASYFAGALLISKEP
                     VIEKTSEFFQQNTWEPENFAYLINSFTHSPETFYYRLTNILSSEMGIKDLFYLCLVKKK
                     DSEKIQILKELHLNHQQAPHANATNEHYCRKWIAVKNLHHLKENETLTDAQISHYKDQG
                     ISYLVISTSQKNPFSDGSNRSYCLGILLNTQTIKKISFIKSPSLKTINVGVTCEACSIP
                     DCEVRQAPPVRLEKEHFNLSMKNAIEKIKKDF"
     gene            12761..13414
                     /locus_tag="PYS58_RS11425"
                     /old_locus_tag="PYS58_11425"
     CDS             12761..13414
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002976801.1"
                     /locus_tag="PYS58_RS11425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11425"
                     /product="double zinc ribbon domain-containing protein"
                     /protein_id="WP_276285402.1"
                     /transl_table=11
                     /translation="MILDLLFPNRCLHCNRIIEAELLVCNLCFGQIHFTYYDYTKNNPV
                     KERCKLFFPVENTYALIQFEEENLSRKIIHELKYRNREITGKILAEWTIERLNFKDQKP
                     DLLVSVPLHPKKQRERGYNQLHLYTETLSKHYQIPFDHELIKRNYYSKAQALKDKKHRL
                     ETINTFSTTQPITGKHILLIDDVFTTGTTISSIAWEILNAGDNKISVLVMAMDV"
     gene            13519..14205
                     /locus_tag="PYS58_RS11430"
                     /old_locus_tag="PYS58_11430"
     CDS             13519..14205
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (1-107). E-value: 5.2e-18.
                     Score: 57.5. Matches aSDomain:
                     nrpspksdomains_PYS58_RS11430_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002976799.1"
                     /locus_tag="PYS58_RS11430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11430"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_276285403.1"
                     /sec_met_domain="PF00561 (E-value: 1e-12, bitscore: 46.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 2.1e-06, bitscore:
                     26.2, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.5e-09, bitscore:
                     34.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPNLVLLHGALGHSEIFTPYLDHLSNYFTIHTPLFSGHGNRELPT
                     GGINIEKYTQELADYCKENNITDVHILGHSMGGYVALCYAMKYPKNINSIMTLGTKFDW
                     TEEQAVKESKMLNPDVIVEKIPQYAQTLEKQHGPKWKQLLPAIADLMVDLGKNPPLKNN
                     FAGINIPVQIMVGDKDSMVSIDESTAVYRELPNTKLAVLPETKHPMDKVRPSLLLSLIK
                     DFWNLS"
     aSDomain        13522..13839
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PYS58_RS11430_Abhydrolase_1.1"
                     /evalue="5.20E-18"
                     /label="PYS58_RS11430_Abhydrolase_1.1"
                     /locus_tag="PYS58_RS11430"
                     /protein_end="107"
                     /protein_start="1"
                     /score="57.5"
                     /tool="antismash"
                     /translation="PNLVLLHGALGHSEIFTPYLDHLSNYFTIHTPLFSGHGNRELPTG
                     GINIEKYTQELADYCKENNITDVHILGHSMGGYVALCYAMKYPKNINSIMTLGTKFDWT
                     EE"
     CDS_motif       13723..13764
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PYS58_RS11430_0001"
                     /evalue="6.20E-05"
                     /label="NRPS-te1"
                     /locus_tag="PYS58_RS11430"
                     /protein_end="82"
                     /protein_start="68"
                     /score="15.6"
                     /tool="antismash"
                     /translation="VHILGHSMGGYVAL"
     gene            complement(14208..14858)
                     /gene="upp"
                     /locus_tag="PYS58_RS11435"
                     /old_locus_tag="PYS58_11435"
     CDS             complement(14208..14858)
                     /EC_number="2.4.2.9"
                     /GO_function="GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="upp"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016198921.1"
                     /locus_tag="PYS58_RS11435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11435"
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="WP_185247788.1"
                     /transl_table=11
                     /translation="MLTILSQNFSLVNEWINELRNVDVQHDRMRFRRNMERIGEIAAFE
                     ISKGLEVRDIEIQTPLDTIKSREIAVQPVITTILRAGVPLFEGILNYLDRADCGFVAAY
                     RKHDANDYFSIKQDYLTCPSIEGRPLIVADPMLATGASLIEAIKDLLTNGNPTQLHIVA
                     AIASRQGVETVQNAYPEAHIWVGAIDEELTSKGYITPGLGDAGDLSYGEKLQR"
     misc_feature    complement(14896..14912)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.03"
                     /tool="antismash"
     gene            15001..18918
                     /locus_tag="PYS58_RS11440"
                     /old_locus_tag="PYS58_11440"
     CDS             15001..18918
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (27-403). E-value: 5.9e-96.
                     Score: 313.5. Matches aSDomain:
                     nrpspksdomains_PYS58_RS11440_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (527-581). E-value: 8.1e-09.
                     Score: 27.7. Matches aSDomain:
                     nrpspksdomains_PYS58_RS11440_PP-binding.1"
                     /NRPS_PKS="Domain: TIGR02353 (610-1301). E-value: 2.1e-181.
                     Score: 596.6. Matches aSDomain:
                     nrpspksdomains_PYS58_RS11440_TIGR02353.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     TIGR02353"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002976795.1"
                     /locus_tag="PYS58_RS11440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11440"
                     /product="Pls/PosA family non-ribosomal peptide synthetase"
                     /protein_id="WP_276285404.1"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-99, bitscore:
                     331.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7e-07, bitscore:
                     27.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR02353 (E-value: 1.6e-179, bitscore:
                     596.6, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSLILGKISTEFIKDETLPELLVPTFEKYKDKTAFIFKDKKISY
                     AELDSWSNAIATQLQSQGIQPGDCVGVWYPRSLELPVAILGILKAGASYIPLDREMPED
                     RIKKVFTDINVKTYFSDTDANIHCQPLSIAAQPQEVVPAPIISQTPGNWAYVLFTSGST
                     GNPKGIPISHRNICHLIRSENDFIEIKDTDIVYQGFSVSFDMWCEEVWISLFAGATIWI
                     ADATTVKAIDELSHVLTENKITVLHAVPSILAIIDEVPSIRFINTGGEACTKQVQEKWA
                     KPYRIFINSYGPTETTVSSNMIKLNNQDELTIGPPLPNYHIAVVDENMNILPRGERGEM
                     VISGPGVSNGYFNLPELTEQKFLPNPFPELPGDKIYKTGDAVTIREDGFIDFQGRIDDQ
                     IKLRGYRIELGEIETRMNQLQDVSSVAVSVKEDANGQGQLVGYVVMSNEASFDENKMRK
                     ELAQFLAPYMVPISIIQMKEMPRMPSGKIDRKRLPIPESFTVHKKNDNIKINIEAPIEE
                     RLLQTLKWVFPGKEINLQQDFFTDLGGHSLLAATLVSHLRQKAGIPTASLKEIYENRPL
                     SAYSDCLKKKQAQKPSHHEPFHRVSTLQYIACNIAQTISLLVVFALLSIQIFFPYLSYY
                     YFQLNGYGLHYALLSAFLLYTLIPPVYSLIIVLTKWLVIGKIKEGDYPLWGWYYFRWWL
                     WKTIKRLMPSEFIVETPLYPKYLKLLGVKVHPSAQLSLLPIAAEDLVTIDENVNTSSGC
                     SIDNASVENGILRIRKVHIKAHSYLGSSVIVCGDTVIEEFGELQDLSCLNEGKKIGYGE
                     VWNGSPAEKVRIKTGAELEAPKLSSASKRNRYALLYSISLFFFPLLIVLPLAPTLYTLY
                     YLDDRSSDYSFYYLWQAPILSTVYILLFIAVVSILTRILQYNMKPGVYPVYSFTYYRKW
                     IKDQIFNLSLIIVHPLFASIYISKFYRMMGAKVGKNSEISTASDVSHHLLEIGEGSFIA
                     DAVILGEHDVRNEKLILSKTTIGNNSFVGNSGLIPQGYELGDNMLIGVLSKAPSEEQLK
                     NASERDWFGSPPIGLPSRQKSDLFQDRLTYNPPFRLKLARAIVEGIRIILPQTVVIICS
                     VLFIAYTSTYLEGRIHYLLLFAPFYYLGIVALPSFFFTALLKWIFIGKYKKTEMPMYSL
                     KVWLSEGITTIYEALPVLFFLDFLRGTWWLPFFMRFLGVKIGKKVWLNTTDITEFDMVS
                     IGDESMLNEDCGPQTHLFEDRIMKVGSVKIGSQTTINSRTIILYDTEIGDNVNIAPLSL
                     VMKGEILSDNTSWLGSPLRGK"
     aSDomain        15082..16209
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PYS58_RS11440_AMP-binding.1"
                     /evalue="5.90E-96"
                     /label="PYS58_RS11440_AMP-binding.1"
                     /locus_tag="PYS58_RS11440"
                     /protein_end="403"
                     /protein_start="27"
                     /score="313.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="EKYKDKTAFIFKDKKISYAELDSWSNAIATQLQSQGIQPGDCVGV
                     WYPRSLELPVAILGILKAGASYIPLDREMPEDRIKKVFTDINVKTYFSDTDANIHCQPL
                     SIAAQPQEVVPAPIISQTPGNWAYVLFTSGSTGNPKGIPISHRNICHLIRSENDFIEIK
                     DTDIVYQGFSVSFDMWCEEVWISLFAGATIWIADATTVKAIDELSHVLTENKITVLHAV
                     PSILAIIDEVPSIRFINTGGEACTKQVQEKWAKPYRIFINSYGPTETTVSSNMIKLNNQ
                     DELTIGPPLPNYHIAVVDENMNILPRGERGEMVISGPGVSNGYFNLPELTEQKFLPNPF
                     PELPGDKIYKTGDAVTIREDGFIDFQGRIDDQIKLR"
     aSModule        15082..18903
                     /complete
                     /domains="nrpspksdomains_PYS58_RS11440_AMP-binding.1"
                     /domains="nrpspksdomains_PYS58_RS11440_PP-binding.1"
                     /domains="nrpspksdomains_PYS58_RS11440_TIGR02353.1"
                     /locus_tags="PYS58_RS11440"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       15253..15294
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PYS58_RS11440_0001"
                     /evalue="2.50E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="PYS58_RS11440"
                     /protein_end="98"
                     /protein_start="84"
                     /score="14.4"
                     /tool="antismash"
                     /translation="LGILKAGASYIPLD"
     CDS_motif       15460..15519
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PYS58_RS11440_0002"
                     /evalue="4.80E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="PYS58_RS11440"
                     /protein_end="173"
                     /protein_start="153"
                     /score="28.3"
                     /tool="antismash"
                     /translation="AYVLFTSGSTGNPKGIPISH"
     CDS_motif       15997..16086
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PYS58_RS11440_0003"
                     /evalue="3.50E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="PYS58_RS11440"
                     /protein_end="362"
                     /protein_start="332"
                     /score="35.3"
                     /tool="antismash"
                     /translation="PRGERGEMVISGPGVSNGYFNLPELTEQKF"
     CDS_motif       16174..16239
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PYS58_RS11440_0004"
                     /evalue="2.50E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="PYS58_RS11440"
                     /protein_end="413"
                     /protein_start="391"
                     /score="35.5"
                     /tool="antismash"
                     /translation="FQGRIDDQIKLRGYRIELGEIE"
     aSDomain        16582..16743
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PYS58_RS11440_PP-binding.1"
                     /evalue="8.10E-09"
                     /label="PYS58_RS11440_PP-binding.1"
                     /locus_tag="PYS58_RS11440"
                     /protein_end="581"
                     /protein_start="527"
                     /score="27.7"
                     /tool="antismash"
                     /translation="PGKEINLQQDFFTDLGGHSLLAATLVSHLRQKAGIPTASLKEIYE
                     NRPLSAYSD"
     aSDomain        16831..18903
                     /aSDomain="TIGR02353"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PYS58_RS11440_TIGR02353.1"
                     /evalue="2.10E-181"
                     /label="PYS58_RS11440_TIGR02353.1"
                     /locus_tag="PYS58_RS11440"
                     /protein_end="1301"
                     /protein_start="610"
                     /score="596.6"
                     /tool="antismash"
                     /translation="AQTISLLVVFALLSIQIFFPYLSYYYFQLNGYGLHYALLSAFLLY
                     TLIPPVYSLIIVLTKWLVIGKIKEGDYPLWGWYYFRWWLWKTIKRLMPSEFIVETPLYP
                     KYLKLLGVKVHPSAQLSLLPIAAEDLVTIDENVNTSSGCSIDNASVENGILRIRKVHIK
                     AHSYLGSSVIVCGDTVIEEFGELQDLSCLNEGKKIGYGEVWNGSPAEKVRIKTGAELEA
                     PKLSSASKRNRYALLYSISLFFFPLLIVLPLAPTLYTLYYLDDRSSDYSFYYLWQAPIL
                     STVYILLFIAVVSILTRILQYNMKPGVYPVYSFTYYRKWIKDQIFNLSLIIVHPLFASI
                     YISKFYRMMGAKVGKNSEISTASDVSHHLLEIGEGSFIADAVILGEHDVRNEKLILSKT
                     TIGNNSFVGNSGLIPQGYELGDNMLIGVLSKAPSEEQLKNASERDWFGSPPIGLPSRQK
                     SDLFQDRLTYNPPFRLKLARAIVEGIRIILPQTVVIICSVLFIAYTSTYLEGRIHYLLL
                     FAPFYYLGIVALPSFFFTALLKWIFIGKYKKTEMPMYSLKVWLSEGITTIYEALPVLFF
                     LDFLRGTWWLPFFMRFLGVKIGKKVWLNTTDITEFDMVSIGDESMLNEDCGPQTHLFED
                     RIMKVGSVKIGSQTTINSRTIILYDTEIGDNVNIAPLSLVMKGEILSDNTSWLGSP"
     gene            18964..19446
                     /locus_tag="PYS58_RS11445"
                     /old_locus_tag="PYS58_11445"
     CDS             18964..19446
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /locus_tag="PYS58_RS11445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11445"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_276285405.1"
                     /transl_table=11
                     /translation="MNYSIKKIKIKENLSIVDELVGELHISEKEMNENTADWSQIRDNY
                     LRFMAECEEENEGSFLIAEIDGKAIGFLFGYIDERDESNFELGEGNDLYVSEGYVKKEY
                     RKQGIYTALNKTFEEMYSKRNIRKIYRFTLCNNDTMQRWLASQGYRPVRIVYEKWL"
     gene            complement(19579..20889)
                     /gene="der"
                     /locus_tag="PYS58_RS11450"
                     /old_locus_tag="PYS58_11450"
     CDS             complement(19579..20889)
                     /EC_number="3.6.5.-"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="der"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018676623.1"
                     /locus_tag="PYS58_RS11450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11450"
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="WP_185247785.1"
                     /transl_table=11
                     /translation="MSNIVAIVGRPNVGKSTLFNRLLERREAIVDSTAGVTRDRHYGKS
                     DWNGVDFTVIDTGGYDVGTDDIFEEEIRKQVQLAVDEATSIIFMMNVEEGLTDTDHEIY
                     RLLRRSNKPIYIVINKVDSSKEELPATEFYQLGIDKYYTLSSATGSGTGDLLDDIVKDF
                     PTTEYKDPFEGLPKITIAGRPNVGKSTMTNALLDVERNIVTDIAGTTRDSIQTLYNKFG
                     HEFVLVDTAGMRRKSKVNEDLEFYSVMRSIRSIEYSDVVIIMVDATQGWESQDMNIFGL
                     AQKNRKGIVILVNKWDLIEDKQTNTMRDFEKAIKDKIGQFQDIPILFVSALTKQRILKA
                     VEVAMEVYEDRKKKIKTSKLNEVMLPIFENTPPPALKGKYIKIKYCVQLPTPSPQFVFF
                     CNLPQYVKEPYKRFTENQLRKEFGFTGVPIEVYFRQK"
     misc_feature    complement(20956..20972)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 21.04"
                     /tool="antismash"
     tRNA            21147..21217
                     /anticodon=(pos:2492776..2492778,aa:Gln,seq:ttg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="PYS58_RS11455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="PYS58_11455"
                     /product="tRNA-Gln"
     gene            21147..21217
                     /locus_tag="PYS58_RS11455"
                     /old_locus_tag="PYS58_11455"
     misc_feature    complement(21357..21372)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.69"
                     /tool="antismash"
     misc_feature    complement(21675..21684)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            21690..23327
                     /locus_tag="PYS58_RS11460"
                     /old_locus_tag="PYS58_11460"
     CDS             21690..23327
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007847062.1"
                     /locus_tag="PYS58_RS11460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11460"
                     /product="T9SS type A sorting domain-containing protein"
                     /protein_id="WP_276285406.1"
                     /transl_table=11
                     /translation="MKKIYLSACTVCTVLGLSAQEILWQKDIRSSTQDFLSQVTTTIDQ
                     QYLITGSSIQSGKLQPGRQQNNGYDFHLVKLNQQGEEAWEKYFSGNNHDYLSATVSTQD
                     GGFLVAGTSYSGKGLDKKEDSKGGSDIWLIRINEFGDELWQKTLGTSSDEEAKAVIQST
                     DLGFFVAGNVQNSSQGYGSKDVWITRLDKDGNELSQLILGGKGLDEIEKMIPTKDGGAL
                     LGIYSRSSEVRVSGGSGMRDAGSVSAVQNSNPDPRNTNPVSRISKQSENFGEGDYWIVK
                     LDKTGKVEWEKNFGGKGDDHIRMLALTSNGYIIGGESRSERSGNKTVGIEEGTDLWLIS
                     LNERGEEQWQKSYNFKNRDILMGMSVIHSSDDKSSKGILLGGYTQAEGRIEKDDETFWM
                     LYLDGNGNEQWRKHVTGESRQKEERLSDLKLNRDGSIILAGTSAKELGKENWKIVKLGD
                     KQVSDLIAKYDIKIYPNPVSDYAYVEIGFDFKEADIMLYDMSGRQLQNFKTKNRVTKMN
                     TQSLIQGAYLVTIKTDNNKTANAKLIKK"
     gene            23341..26673
                     /locus_tag="PYS58_RS11465"
                     /old_locus_tag="PYS58_11465"
     CDS             23341..26673
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PYS58_RS11465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PYS58_11465"
                     /product="hypothetical protein"
                     /protein_id="WP_276285407.1"
                     /transl_table=11
                     /translation="MKKIYRLIVSSMFILYGALVIAQDNNNSIQKKNIVAFPTSANAYA
                     IDKVGKLAVDMFKGKANINIPFYTINVDGVSIPISLSYNTGGIKLNEIASTVGLGWSLN
                     IPSNISQNIIDKDDKTFSMYTKDINVVNSNFRSVGIYDNDIRQIIDDHYEGIYDTRPDL
                     FNYSLPFGGGSFIFNNDIGYTIPHEDLMITGTNNKKNIKIVNTDGAIYFLSIKNNTSMD
                     SNIPGSTTSSSETLYQIDSIRTITNKKILFEYTKSYYYSEKSITERANIDISDEVSSSA
                     DLPINLPNYERYVGTIGNREKLITKIIFPEGTVYFNYSNDGFPFSDGTSIRKDILSNDG
                     VALRQILVKDKYGKIIKDYNLNFSYFTSNSGTDYQNYRLKLLNIYDSLQKNYYKFYYNE
                     NIPFPARNSNNDDYWGYINSTTYSENSTNIPDKIYTDYTSKNITLPAQYTRNRDTNPDY
                     TSIGILNRIEYPTGGSKYLYYENATKFFTRTNYQWGYTDNFATVMSQPSGNGGSSDNFG
                     NISQTITIPPTYFDGKESPKIKLIFGNTCENNVDDETSQIHDTSCYGNATSNGGYYGTN
                     GKPAVFELNNVNSPINISLSRTGKCSCGYAVDVVYGQYTTINSNIPIGGLRIKKIKDLD
                     NNSFVNTYNYKYDVLDKATNTYKSSGILNMPFQYTTLLKRYVTQAIGGGELAYPYIQKY
                     LVVNNSSTNYNSYGSSDVLTYKQVTEYNELGQNINIFSQINNSDSDKMYTHVYSNYNDW
                     KNGLLEKNIILNKLNDTMKVTTHKYAFNYLKNPKAGFITGTSDQIGFALNLDIVKYLKR
                     VTVVNENPIYVNIYPVTKEIIGINSAKLEHIETTTKEFFGDKSVVTKVLNNYWDTDINK
                     PFNVKSTENIFPSGESVKTEYQYAHQTGNQLLIDKNMIATPLETETRQTINGVTNVLSK
                     SKTIYPTALPTSQTGNLALPMSILSYDIQNPSVVANEVIYDKYDSKGNIVQYTTKDGVS
                     TVIIWGYNGTQPIAKIENAKLENISQSFIDSIVNASNTDASAERNNDETNLLNAFNTFK
                     NNLSGYQITTYSYDPLIGVRSITPPSGIREVYLYDAAGRLKEVRENNQTGKLLKEFNYH
                     YKN"
     gene            26679..30173
                     /locus_tag="PYS58_RS11470"
                     /old_locus_tag="PYS58_11470"
     CDS             26679..30173
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039454.3"
                     /locus_tag="PYS58_RS11470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11470"
                     /product="DUF6443 domain-containing protein"
                     /protein_id="WP_276285408.1"
                     /transl_table=11
                     /translation="MKKIIIPIGMLLLSSSVHAQLSPGENYIQSKTYLDYNGTTPTKTS
                     ETVQYFDGLGRPKQVVNVKASPQGKDVAVPIEYDQFGRQVKDYLPIPQSGTLNGGIIPN
                     PLSNASNTPYGSEKIYSEKILENSPLNRIQQQIQVGNDWSTKPVKFDYQANGLNEVSRY
                     ITTTTWENNATKSTVSLSQAAVYAPGTLYKNTITDEDGNQTLEFKNGKGQTILVRKLMG
                     YMEQADTYYVYNEYDQLAFVIPPNAVQQPITDVLLNDLCYQYRYSGRNLLVEKKLPGKG
                     WEYMVYDRQDRLIATQDANQRPANNWSYTRYDQFGRVVYTGIATDYATRATLQQYVYNK
                     GYNTSNNTTRTPSPSFRLSGMDIYYTNDAIPEVLNNVLTVTYYDTYPAYSFNPSFPSAI
                     QGVDTLKDTVSPEGKSTKGLPVMSLVKNIEDDKWTRNYTYYDTKGRVIGTHSINHLGGY
                     TRTESSLDFAGVAQTVITRHKRLETDTERVITETFTYDHQNRLLVHKHQVDANPVEILT
                     QNTYNELSQLESKKVGGIAVGSSLQQMDYQYNIRGWLTKINDPSNLNGKLFGYGIKYNN
                     PLNSAKSLGRFNGNIAEVDWRNSSEEVLKRYNYEYDTLNRLKNGFYSEPNATNPDNGNF
                     DEYLTYDVNGNINTLKRKAIPVSGGTSTLVDNLEYKYTGNRLNQVIELAMNDTGYEGGN
                     NMIDYDVNGNMTTMKDKNINSIGYNYLNLPNQLFINQKFSGWNHNTNITHLYRADGLKL
                     RTTKYSAIDGDIGDTTITDYLDGFQYRYYDNGLMGGPLLQDKTSFAYEDQAYTKTGSMF
                     PSKPKWQLDFVPTSEGFYSFTENRYIYQYKDHLGNTRISFAKNSAGVLEVTDTNNYYPF
                     GLNHIGGIKGQLGSYKNYKYNGKELQETGMYDYGARMYMPDIGRWGVIDPLAEKMTRFS
                     PYNYAFNNPIRFIDPDGRQNKDVIITGDYKDKTIELLQASVEGQLNLTMDKSGKVTATA
                     VEGVELTEAASTFLQATQDNCNIVVLKTDGDYRLDDGSFYQGGAYGGSKMAGNGKMIGT
                     NVVNPMVSEKIDEALGLPKGVGVLHEGLENYMGILNSPGSPAGTPENKDKGYMAAHKKA
                     NELDPRHKDPGKEYSSEHIKQNIKNTDGKKLYTQEELIYINNKTNVRTSVGRFKTNP"
     gene            30173..30616
                     /locus_tag="PYS58_RS11475"
                     /old_locus_tag="PYS58_11475"
     CDS             30173..30616
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PYS58_RS11475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PYS58_11475"
                     /product="hypothetical protein"
                     /protein_id="WP_276285409.1"
                     /transl_table=11
                     /translation="MKKLILICVLSSINTYSQQENKVNVIAKVIKIDSTKSSFIIYIKS
                     KSGQGIFSIPKICNNQTNYKFKIEKDKSYFFTLKKEIHKHMPENLTQELVETELVDDKV
                     VWSSKMDSTFYEDCTNMCGLYIDNEGKPKQNRSSKKKWLKKKH"
     gene            complement(30771..31136)
                     /locus_tag="PYS58_RS11480"
                     /old_locus_tag="PYS58_11480"
     CDS             complement(30771..31136)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010182964.1"
                     /locus_tag="PYS58_RS11480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11480"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_276285410.1"
                     /transl_table=11
                     /translation="MSIGRIIKKIREDKGLMQKEVSAHLGIGNSNYNKLENGHRELSVE
                     ELLKLSRLFNLTTDQILNYENIIPEEVTIEDKPDFEKLHLINQLDEEDKSMIFKMVDKM
                     LTTKKFKDFFNKNVVAL"
     gene            31288..31473
                     /locus_tag="PYS58_RS11485"
                     /old_locus_tag="PYS58_11485"
     CDS             31288..31473
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003896 - DNA primase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013930.4"
                     /locus_tag="PYS58_RS11485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_11485"
                     /product="CHC2 zinc finger domain-containing protein"
                     /protein_id="WP_276285411.1"
                     /transl_table=11
                     /translation="MEIQAIKEHLHLSEVLQHYNLHSKNNMLLCPWHDDKRASLQVNLE
                     KDFYKCHACGKTGDVI"
     gene            complement(31811..32242)
                     /locus_tag="PYS58_RS11490"
                     /old_locus_tag="PYS58_11490"
     CDS             complement(31811..32242)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PYS58_RS11490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PYS58_11490"
                     /product="hypothetical protein"
                     /protein_id="WP_276285412.1"
                     /transl_table=11
                     /translation="MKNVILLLSTMIMLVSCVYSNTENSHQVITFVNKTNKTLYILSSY
                     EYPDTEVYKQNPDPKLGGYNKVEADQTTQTVLSSKTSYENVYHSLIPSGVMMVYIFDGS
                     TLETKGWEYIKANNLVLKRYDLTLQDLKNMNWVITYDGN"
     misc_feature    complement(32659..32674)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: medium, score: 27.51"
                     /tool="antismash"
     misc_feature    32903..32918
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.84"
                     /tool="antismash"
ORIGIN
        1 gagtttttac taacagcgtt cttccttatt gtcattatgg gagctacgga taaatgggct
       61 aatggtaaat ttgccggtat cgctattggg cttgcactta ctttgattca cctgatctct
      121 attcctatta cgaatacttc tgtaaaccct gcacgatctc tttctcaggc agttttcacg
      181 ggcgggttgg cgatgtcaca gctttggctg ttctgggtag ctccaattct tggtggaatt
      241 gtaggtggat taatctacaa attcttactt cagagagata ctgcagaaat aactgactaa
      301 ttaatattag aacaatacat tatcataaaa tcctgtctga tgacgggatt ttttgttttt
      361 ataaagtttt ttaaacgtaa gttttatgat gaggaagtat tattttcagg aaacaaagaa
      421 atacgacttt atcgctgatg aggtaagtaa tttagccatg tggcaaaaga aaaaatgatt
      481 gctttatttt ttattcttaa gatcaaaagg atttttgaaa atgagttctt catgttttcc
      541 tttgatttcc atttttcgct gaagtaagtt caatgccatt ttcctgataa aaagatcttt
      601 atcattcaac ttccagtaag aatctccatg aagccttttt ggaggacgga taagatagaa
      661 ttccgtatcc caggtatctg cattatgata aaactcaatg attccgcaat gctccggaat
      721 actctcagaa tctaccattc ccataggcag aagaaaactg aatgcattac aaacataatc
      781 tccacaggaa attttatcat gtttcagaaa tttttctccg gtgtctttat tgatatatga
      841 ttttttgaag tcatttttaa aatcgctttt ggaaagtttg atctctattt catgacttct
      901 tcctccagca tcaatgatga gtatatctgc ttcccaatca gcctggaaat agttggtgag
      961 tacgagttct ttctcaaaat cgcaatgggt atggatatat gcgtgaacaa gttcttctat
     1021 tttaagcata atataatgtt tagatcggag acatctgatg tgaaatatga gacttaaatc
     1081 acgaaacgtc ttttatttag ctcaccaata agctacaacc tctgatatca gagtgatcta
     1141 ttctccccag tacctgaaat ttgtccccta ctacttttcc taaatcctgg gttgcaataa
     1201 aggaacagga atacgtattg gctaagtcga tgatattaat tgccccggtt cttccatctt
     1261 tttcatagga taaaggatcc tcaacatttc taatcttaat ctgcatccaa ttaggacact
     1321 gatattcgtt attaccaaga gaataagcct gagataacaa ctctgtcatt gaatattctg
     1381 agtagattgt atctgtattg aagccttcct gcaaaatttt caaaagttca tcttttgtca
     1441 tttcttcttt tcttcctttc attcctccgg tttcgataac aaccaggttt tcaagaacgc
     1501 ttagagattc ctcactgcgt tcggaatgac aataatctaa aaagtctaat aaggcaaagg
     1561 aaactccgaa aagaattacc tttttatcct gtaactggtt taaaagatca aaaagatcgg
     1621 aatgattata aaggaaatat ccgttttcag cttttgccga ttttttcatc agataatcta
     1681 ccatataaat cagagacgaa ttctgtcttt ccaaataact cggtagtaat ccaagaaaaa
     1741 taaaatcctc cggttttcca atgaactgtt caaaactttt gtagatactt tcttcataca
     1801 aatccgtatc agctataaaa tgcttcgaaa gattcatctg cgtggtaccg gaactctgaa
     1861 aaaacaagtc tgtagttgca tttccatcca gaatctgatg gtttttaaac atttcaatcg
     1921 gaagaaatgg aattttcgat acatcatcaa cctcatctgg actgatgttt aaaaaatcta
     1981 caaacttcct atatatctca acattttcat actgataacg aaatgttttc aatgatgcat
     2041 tcaggaaatc ctgttcagtt tttatgttga atatattttt cggttccata atttttttta
     2101 ttcgtcttat tactccagta caaagcaatt attgagataa aatattttta tttaatgttt
     2161 ttttaatatc ggaatttgac tttggtaaac ttcttgcaat cacctaaccg gaatatggat
     2221 taaaaacaga atgagtcccc cactcattct caaattacct ctttttaggg gtaatttttt
     2281 tattttattt ctcgaaagtc ttcagttcaa agtctttttc aaaaacacca taggtaaaat
     2341 aggaaatcca atctcccagg ttgatgtatt ttgaattttg ccctaaatcc agtaccatag
     2401 gaaggtgacg atgtccatat acaaaataat caatcttttg agtcctcagt ttttctttgg
     2461 aataaatgat aagaaactct ttatcttctc ccaggaatgc tttgtcttct tctcctgaga
     2521 tcattttatt tttctgagaa agatataaag ctattttcat agcaatatct ggatgaagcc
     2581 atttgaaaaa ccattgtgct accgggttgg taaagactct tttcatcctt ttgtatccct
     2641 tatctccagg tcccagccca tctccatgag ccagcagaaa ctgttttcct cccatttcaa
     2701 aatactgttt ctggtaaaaa acggtacagc caatctcttc ttccaaataa tctttcatcc
     2761 aaagatcatg atttcctaca aaaaaataaa tatggattcc tctgtctttc agttctgcaa
     2821 ttttccctaa aacacggatg taccctttgg gaaccacatg cttccattca tgccagaagt
     2881 caaaaaggtc acccattaaa aataaaacct gtgcatcttc cttgatctgg tccatccatc
     2941 gtataaatct ttcttcacgt accttacttt ctttaggagt aggtgcacca aaatgctgat
     3001 ctgaagcaaa atatactttt tttccaggtt ctaaattaat tattgttttt aacaccttct
     3061 gatctttatg ggtaataatt attgattatc ttctgcaaac cattctccat aagaattttc
     3121 tgtctcatga agtttgagat aagccagaga aattccttcc ggaagtcttg attttatttt
     3181 ggctgcaata gcatacagca tattttcaca ggttggctgg aaactgcaat aaattacttt
     3241 atgtcctttc tgttcaagat catcacccaa ttctttatgg ggagtgagtg catttaaaag
     3301 cactgcatga tcccaaacgt ctacgatctc agattttacg atacttttga tatctccgaa
     3361 atcaactacc atcccgtttt tagggttatc aatatcatta atcggtttcc ctttcactgt
     3421 tacgaacagc ttataggaat gtccatgcat atttttacat ttcccatcgt aattgtacag
     3481 tacgtgggct gtttcgaatg taaaaatttt tgtaatacgt atcatactgc aaagatatga
     3541 caaaacagtc taactttaaa agtcagactg ctattaataa gttcgaagaa ttcaattgaa
     3601 aatcaataaa aacttaatta atttgataag tgctctgagg ggtttgtctg ttttatgaaa
     3661 ataattccat taaagcattc attaagcttt agaggctccg taattgtaaa tttttctgtt
     3721 ggaggagtaa cgggaccata tcctaataat ctcatcttaa aagactgtcc atatacattt
     3781 tctgagacac cattaaaatc tacaaaataa ttttcgtatt tattattccc cagcttttct
     3841 tcccagctgt tttccaattg ctttggaagt tgataagaac tatatttatt attcttcacg
     3901 gcacgtggat cagttgtcgc actatagctc ccaaaaactg tagaagttgc cagcgcatag
     3961 tatttattcc catacttctt tttaagatac ccacccattc cgtcaacaat gatgggtttt
     4021 aatgcaatat gcccgttatg agcaaaaaga atcatcttct tattatatcc tgattgaatt
     4081 gtctcaatca tttcagccat aataaggtct ctggaaacat catagttttt tttacttgcc
     4141 tcatagggaa ttttaaaccc ttgttcaagg tgataaagag caagctttga attcacatct
     4201 attttttgcc caaacaaact atctaatttc ttagttaaga gaaatccttc tgttccattt
     4261 tttatgacca cgttcatatc cagtttaaag gatgggtcat tctgcttttc ccacatttca
     4321 tcctgtaatg ttgctttttt cccaatttca ttggttatct cggtatattc ttttcctagg
     4381 tcaccctttt ttttcagaat ttctgcacta tgggtgagaa catctgtatc aaatccggaa
     4441 ataatgactt tatctttatg atttttattg tattccctga tccatatcaa cagattatag
     4501 atctcttttg tttgccagat agaagtgatg tattttttta tggcgatatt taagtcgaca
     4561 tctgaattga cagcctcatt tagcagtgaa gcatcaccat aagcactttc aaaggctaca
     4621 attctaaatt catttttgct aattaattgt tttgaaatct cacttctaat ttcattaaac
     4681 tctttggttc catgggttcc ttcccctagc ccaactatag tatgagcttt cagctgttca
     4741 ctgatgccct ttacagcctt cgtcatattt ttatgatctg caaatgtctt cggaatttga
     4801 gttacatttt gagcgttttg cgagaaacct attgaaaaaa acaatagaaa agcaaaagtc
     4861 aaggatttat tatttagcat gattataata tgttttttag tttagttgat tttcaaagtg
     4921 agattattat ctctggttcc gtctgtgtta gcagcattgt aaggaactgt taaccatccg
     4981 gttctattat tcatcacaaa tttaaatccg taagtttttc ctttttcaaa ctgagatttt
     5041 ggcactgtaa gctcaaaaac attattcttt tttggaatca tctgatagga tggatcacct
     5101 ggattccaat tgttaaatac acctgctact gaaacactct taatgaattc tgtacttaac
     5161 ttttcaggat attgatagga aaaaataact ttatcatttt ctattctgta accatatact
     5221 ttcttcttca gattaggatg agcaaaaggt tcagcaatgg tgatttcttc cgccagcata
     5281 taaggttcca tcagattttt atcgataatc cctgcaatat gattcaccat ttgatacatg
     5341 acaggaaatc ctttattccc attatacatt acaacaatcg ccatattatt atccggaaaa
     5401 atactgtaag cacttacatt tccacctgaa aagccatatg atttggtctt attattatct
     5461 gtaatttccc agccatggcc gaattcccaa tcgttatttt tataatcaaa cggtttccac
     5521 atcatctttt gggtttccgg tttcagaaaa tcatttttgc tgaaatggat actccactgt
     5581 aaaaaggctg gaagggtaac cgccagacca ttggcagaat gaaatctcaa tccatgaata
     5641 accgttgatt tttcatacct cttcttttca ggtttataat catatttaac gattctatta
     5701 ggaatttttt caattgagtt ggaagaaaac actacctgat tcttagagtc tggaaattga
     5761 ttttccagaa tatattcttc aaaggttttt cctgttattt tttcaatgat catcgtaatc
     5821 aaaagataat tagtctggtt ataccggtaa tgatctccgg cttcaaactc tattttttct
     5881 tttgacaagc gatctatggc ttctttatgc gttgctttct ctgataaatc ttttacatca
     5941 agcatatccg gaagtcctga agaatgggaa acaatatttt taacctgtat gttttgccag
     6001 tctttgggaa ggttatctac atattttgaa atcttatcat ccaacgacac ctttccttcc
     6061 tcaataagtt taaaaaggcc aacattagcc attagttttg tagtagaata taccctgaac
     6121 atggagttgg ggttcacttt tttatcactt tccagatcct cacgtccata atattgttgg
     6181 aatgtcacct tatcattttt tacaattccc acggccattc cgggaatttc attgatttgg
     6241 ataacatttt ttatatagct gtcaatggct tttgactgtt ctactgtctg actgaatcct
     6301 aaaatggata cattaaaaaa taatgctgct aaaatggagt gcttcatggt ttgttcatgt
     6361 atgtatttaa taagacagct acaaacttta ttatgttaca gaatttttga cttttattta
     6421 taaataactc tatacgtttt atttaggttt taacgaatca atttcatatc ccaattcgga
     6481 taaataatcc aacccatttt gtttttccat tttattcttt ccattccagc ctttttctat
     6541 tccttttaca ataagttttt ggatgtattt tggttcattg atattgacat tttctaatga
     6601 atctgttact acattcatca aactgattcc ggattttaga ggttgcccca tgaaataatg
     6661 ttcaaaggtt agaaaatcaa tgattaatgg agtctgtttt tcaccactta aaaatatttt
     6721 tactgtaagt gtatttgttt ctgctccagg atgatattta tctgtaacta aatacagata
     6781 cttttcatgt tcaacagtta tctttcttaa tttattcttc aatctgcttt tctaatttct
     6841 ccagccaatt actttccaat cgttttattt tcttcgcttc cgtatcaaac agtatccaaa
     6901 gcgtacttga atctacaact agttcgtcat gacaataaaa ttctactttt cttggctgtt
     6961 tagcaccttc tggttcctgc ggataagttt tcacagtgat tacatcattc agatacactt
     7021 gttttttata acggatatga tgatccagaa gcatccagac atcattttca tattctgttt
     7081 tattttttaa aagattccaa tgttcagcgg ctacttcttc tacccaatgc acatactgta
     7141 cgttattaac atgattattc tgatcgatat gttcttccgt tactttaatc tgtttttcat
     7201 atactaaact catctcattg aaatatttac tcaaatttag tatttaaaac aagaagggtt
     7261 ctaagatttt ccctacaaaa ttcatatcta gtatataaaa aaacggagcc aggctgatct
     7321 gattccgttt tgcaatattc aatagattga aattattttt tagcttttcc tgccgctggc
     7381 ttagaagcag ttgctgaagc tcctaatttt gtttttacct gtgcagtaat atcttcactt
     7441 tcatctgtgt aaacaagatt acttccctgt gttgcaatat cgaatacaaa gctcaggttt
     7501 ctttctttcg atacggcaaa aatagctgtc tttattttct gttgtattgg agtaaataat
     7561 tcgccttgtt tagcagaaat ttctttagct gcctgcgctc ttgcttcttc aattttttta
     7621 cccagtgcat ctaattctgt ttgtgctgca ataagttcct tagttaaggc ctctttatta
     7681 gtctcgttaa atgtcttttc tttatcttgt gctactttca acttcgtctg atactcattg
     7741 attagtttat caatttcagt ctgctttgtt ttagtcaggt tatcaatagc ttcacccgct
     7801 gttttaactt cggtcatact gtcaaaaata tctgcagtgt ttacacttcc gattttttgt
     7861 tgagcattgg cagcattggc agttaaagtt aatcccgctg caataaaaaa taatttaatt
     7921 agtttcatta tgatatatac tttttttgaa aaatttactt tttttcagtg tccaaatata
     7981 atataatttt tcatttacaa tcattctact ttttttagat ttcatgaaga tataaacctt
     8041 gtcttaaata gctatatcac ccaaaacatc ttctattaaa attcctacta acataaagcc
     8101 ctccccaaaa accggagaga gcttcgataa tatgtataat gcaaaaaact gaattttaat
     8161 gaaactgtgc cgtttctgta gaatctttca tggctacggt agcagaagat ccgttggtaa
     8221 caatattctg aacctcatca aaatatcctg ttcctacaaa agactggtgt tttacagctc
     8281 tgaatccttt ttgctgtaat gcaaattcac gttcctgaag ttctgaatac cccgccattc
     8341 ctttttcttt ataagctaaa gccaattcaa acattgctgt attcaaagca tggaatcctg
     8401 ccaatgtaat gaactggaat ttatagccca tttttgccaa ttcttcgcgg aaagtagaca
     8461 tttcctcaac gcttagtttg gctgcccagt taaatgaagg tgagcagtta taagcaagca
     8521 tttttccggg aaactttgaa tgaattccat cagcaaatct tttagcctgt tccaaatccg
     8581 gatttgaagt ttccatccat atcagatctg cataaggcgc ataagataaa ccacggtcta
     8641 ttccctgttc cactccattt cttacaacat agaatccttc agaagttctt tcccctgtta
     8701 cgaatttctt gtctctgtca tcaatatctg aggttagtaa atctgctgca tcagcgtctg
     8761 ttctcgcaat aataagactt ggaaccccta atacatcagc tgctaaacgt gctgcaatta
     8821 atttattgat tgcttcctgg gtaggaacca gtacttttcc tcctaaatgt ccacatttct
     8881 ttgcagaaga aagctgatct tcaaagtgta caccagcagc acctgcttca atcatttgct
     8941 tcatcagctc aaatgcattc aggtttcctc caaaacctgc ttcggcatct gcgataatcg
     9001 gaacaaggta ttctttatcc ccggttccac tcactgactg aacctggtct gctcttagta
     9061 aagcattgtt gatttttttt accacagatg gtactgaatt cgctggatat aaagattggt
     9121 ccggatacat ttctccggat aaattagcat ctgcagctac ctgccatcct gaaagataga
     9181 tcgcttccaa tccggcatcc acttcttgta cagcttggtt acccgttaaa gcaccaagcc
     9241 ctgccacata atcctgggta tttaatttct cccagaattt tttagccatt tccgttgcaa
     9301 tggtataatc aatagtataa gaaccacgta gtcttaaaac ttcttctgcc gtataaggcc
     9361 tttttacacc attccagcgc gggtttgtca gccaatcttg ctctagagcc tggatttgtt
     9421 cttgttttgt tttcataata tttggatttt gtttgttgag ttataaaatt cgagttacgg
     9481 gatttcggaa acattcagat atttcaaatc ttgttgccaa actaaataaa aggatacgct
     9541 ttcagggtta aaaattcttc aaagttttct gagaagatca actcattaaa caattctttg
     9601 gcaaggttga attttccctt tttaaaacga acctccccta catatttttc aatattgtcc
     9661 atttcttcag attcccattg aagaaccata tttcgggtta atgttctgtc atcacttaat
     9721 accgcttcgt tttttaacca ttgccagatt tgggttcttg aaatttcagc cgtagctgca
     9781 tcttccatca aattataaat ggccgccgcc cctactccca tcagccagct ttcgagataa
     9841 agaattccta cattgatatt ttttcttact cctttctctg taatctcgcc ttttggaatt
     9901 tccagcaatt cactttcctg tatattgtat tctaattttt tatcaatctg atttttagaa
     9961 ggcatatatt catcaaaaac atccttagcc aatgaaacta atgcagggtg tgccacccag
    10021 gttccatcat gcccattttt cacttctctt tctttatcgc ttcttacttt ttcgaatgct
    10081 atagtattgg ccttgtcatc atttttcaca ggaatctgtg ctgccatccc acccatagca
    10141 tgaacatttc ttttatggca accttcaatc accctttttg aataggcact cataaaaggt
    10201 gatgtcattg ttacctgatc tctgtccgga accataaact ccggaaggtt tctgaatttc
    10261 ttgatgtatg aaaaaatata atcccatctt ccacaattca gtccggagct atgttctttt
    10321 aattcatata aaatctcatc aatctggaat gaagcggtaa tagtttcaat taaaactgtt
    10381 gctttaatcg ttccttgtgg aattcccaga tattcctgtg caaagacaaa tacctcattc
    10441 caccatcttg cttctttgta atgttctaat tttggaagat aaaaataggg accacttcct
    10501 ttttctaaaa gattttttgc atttctgaaa aagtaaatcc caaaatccgt cagggatcca
    10561 gatgtttctt catcattgat cttgatatgt ttttcgggaa gatgtaatcc tcttgggcgc
    10621 actaataaaa cagctgtctt ttcattcagt tgataagctt ttcctgcttc attgacaaaa
    10681 tcaatagttc tgtttatagc atcggaaagg ttaatttgcc cttccatacc gttttcccag
    10741 gttggcgaac tactgtcttc aaaatccgcc atgaaggtaa aggctccgga attcaaagca
    10801 ttgataatca ttttacgatc cacaggacca gtaatctcca ctcttctgtc taataaatct
    10861 tccggtaatg gagcacacac ccaatttcca tttctgactt cttctgtctc tttcagaaat
    10921 tttggaagat taccctgatc aaattctttc tgagtttttt ttctttcttc cagaagttcc
    10981 aaccttttat gattaaaatt ctgatgaagt gccattaaga aatctatcaa atctggtgtg
    11041 aaaatttctt caaactgctt ttgagccgta atttttaatt gagtcttggt ttccataaca
    11101 tgttgatttt gtgatttgat gttacaaaca taaataaaaa ttttcacaaa cagcgaacgt
    11161 tcgctaaatt tatttaaaaa ttattatgcg aataatcgca tctaattatt tatatttgag
    11221 taatgaattc agaaagtgac tttatcaaaa cagttttcgg gctaaaactg aaacaacaga
    11281 gacaaaagaa aaattggtct ttacaggatc ttgccgtaaa aaccggacta tcaaaatctt
    11341 atcttaatga gattgaaaat gggaagaaat atccgaaaca tgataaaatc atccagcttt
    11401 ctgatgctct aaactgtact tttgatgatt tagtttctac aaaactagac aaaagtcttg
    11461 ctccttttaa tgagattcta caatctgatt tcttcaaaga agttcctttg gagttatttg
    11521 gaattaacaa gaataacctt atcagtatca ttagtgatgc acctaaaaaa gtaaccgcct
    11581 ttatcaatgc cctgatagaa atttctcaga attacaatct gggaaaagag agattttatt
    11641 tcgctgtttt aagatctttt caggaattat atgataatta ttttccggaa attgaagata
    11701 aggtaagcct gtttacagaa gaaaatcacc ttcaaattga taaagattta aaggctgaca
    11761 ttctggaaac cattctttct gaaaaattcg gttataccat tcaatgggag agttttgaaa
    11821 agtatggaac actggataat ttacgatcct tgtttttccc ggaaaaaaaa ttattactcc
    11881 tgaataaaaa gcttgaaaaa gatcagaaaa cctttattct ggcaaaggag attgggttta
    11941 atgtattgga attaaaagtt cgcccaacca cttattcatg gcttgacttt gggagctttg
    12001 aagaaatcct gaataatttt tatgcttctt actttgccgg agcattgtta atatccaaag
    12061 aaccagtaat tgaaaaaacc tctgaatttt tccagcaaaa tacctgggaa ccggaaaact
    12121 ttgcctatct catcaacagt tttacccatt ctcctgaaac tttttattat cgactgacta
    12181 atattctttc ttcagaaatg ggaattaagg atctgtttta tttatgtctg gttaaaaaga
    12241 aagactctga aaagattcaa attcttaaag aacttcatct aaatcatcag caggcccctc
    12301 atgccaatgc aacgaatgaa cattattgca gaaaatggat tgctgtgaaa aacctgcatc
    12361 acttaaagga gaatgaaacg cttacagatg ctcaaatttc ccattacaaa gatcagggaa
    12421 taagctatct ggtcatttcc acctctcaga aaaatccttt ttccgatggc agcaacagaa
    12481 gttattgcct ggggatttta ctgaatacac aaacaattaa aaaaataagc tttataaaat
    12541 ctccatcctt aaaaaccatc aatgtgggag taacgtgtga agcctgcagc attccggatt
    12601 gtgaagtaag gcaagctcca ccggttcgat tggaaaaaga acattttaac cttagtatga
    12661 agaacgctat tgagaagata aagaaggatt tttaagctta ggacttagat tttgggagta
    12721 aagactcaaa actattttat atcttagtaa aaacacactt atgatattag acctgctttt
    12781 tcccaaccgg tgtcttcatt gtaacagaat tattgaggcc gaacttttgg tttgtaattt
    12841 atgttttggg caaattcatt ttacatatta cgactacacc aaaaataatc cggtgaaaga
    12901 aagatgtaaa ctcttttttc ctgttgagaa tacctatgca ctcattcagt ttgaagaaga
    12961 aaacctaagc cggaaaatca ttcatgaatt aaaatacaga aacagagaaa tcacgggaaa
    13021 aattctggca gaatggacta tcgagcgatt gaatttcaaa gatcagaaac ctgatcttct
    13081 ggtaagcgtt cctcttcatc ctaaaaaaca gagagaaaga gggtacaatc agcttcattt
    13141 gtatacagaa actctttcaa aacactatca aatccctttt gatcatgaac tcatcaagag
    13201 aaactattac tccaaagcac aagctctaaa ggataagaaa catcgattgg aaacaatcaa
    13261 cacattttcg actacccaac ccataacagg aaaacatatt ctgctcattg atgatgtttt
    13321 taccacagga actaccatat cttccattgc ctgggaaatt ctgaatgccg gagataataa
    13381 gataagtgtc ctggtaatgg cgatggatgt atagatacag cattcagact tctttttact
    13441 taataccaag atttcaatat gcctttcttt cttttctgtt ccgattcttt tgcttaattt
    13501 tccgaaaaac aaataatcat gcccaatttg gttttattac atggagcttt aggccattct
    13561 gaaatattca ccccttatct ggatcacctt tcaaactatt ttacaatcca tacaccttta
    13621 ttttcaggac atggaaatag agagctccct acaggcggaa tcaatataga aaaatacact
    13681 caggagctag cagattattg caaggaaaat aatataaccg atgtacatat tctgggtcac
    13741 agtatgggtg ggtatgttgc cctttgttac gccatgaaat atcctaaaaa tataaattcg
    13801 ataatgactt tagggacaaa attcgattgg accgaggaac aggctgtcaa ggaaagcaaa
    13861 atgcttaatc cggatgttat tgttgaaaaa attcctcaat atgcacaaac tttagagaaa
    13921 caacatggtc cgaaatggaa gcagttactt ccggctattg ctgatttaat ggttgatctg
    13981 gggaaaaatc caccactaaa aaacaatttt gctggaatta atattccggt tcagattatg
    14041 gtaggagata aggacagcat ggtaagcatt gatgaaagta cagccgtata cagggaactt
    14101 cccaacacaa aattggccgt acttcctgag acaaagcatc ccatggataa agtacgacca
    14161 agtttattat tgagtttaat aaaagatttc tggaaccttt cttaaaatta cctttgcagt
    14221 ttttccccgt agcttaaatc tccggcatca cccaaaccag gtgtaatata acctttggat
    14281 gtcaattctt catctatagc tcctacccaa atatgagctt caggataagc attttgaact
    14341 gtttcaacac cttgtcttga agcaatagct gctacaatat gaagctgagt tggatttcca
    14401 ttggtcagta gatctttgat tgcttcaatc agtgaagctc cggttgccaa cataggatct
    14461 gctacaatta aaggtcttcc ttcaatactt ggacaagtta aataatcctg tttgatagaa
    14521 aaataatcat tggcatcatg ttttctgtag gcggctacga aaccacaatc agctctgtcc
    14581 aaataattaa gaattccttc aaataacgga actcctgctc ttaaaatggt cgtaattact
    14641 ggctgtacag caatttctct gcttttaatg gtatctaaag gggtttggat ttcaatatct
    14701 cttacttcca atcctttact gatttcaaag gctgcaattt ctccgattcg ttccatgttt
    14761 cttcggaatc tcattcggtc atgctgaaca tcaacgtttc gaagttcatt aatccattca
    14821 ttaacaaggg aaaaattttg cgataaaata gtaagcatga agatttaggt tttaattaca
    14881 attagtaaac attgattggt gcaaaattac aactaaaaaa cgaatttata gattggatat
    14941 aaatagaaaa aaactacatt tatataattt tcccaacata tatattttat ttttttaatg
    15001 atgaaaagtt tgattttagg taaaatcagt acagagttta taaaggatga aactttacct
    15061 gaattgctgg ttcccacctt tgaaaaatat aaggataaaa cagcctttat atttaaagat
    15121 aaaaaaattt cgtatgctga attggacagc tggagtaatg ctattgccac acagttacaa
    15181 agtcagggca tacaaccggg tgactgtgta ggagtctggt atccgagaag tctggagctt
    15241 cctgttgcga tacttggaat tttaaaggct ggagcttctt atattccatt agaccgggaa
    15301 atgcctgagg atagaattaa aaaagttttt acggatatta atgttaagac ttatttttcg
    15361 gatactgatg caaacatcca ttgtcagcct ttatcgattg ccgctcaacc gcaggaagtc
    15421 gttccggcgc caataatcag ccaaactcct ggtaactggg cttatgtact gtttacttca
    15481 ggaagcacag gcaaccctaa gggaattcct atttcccata gaaatatctg tcacctgata
    15541 cgctctgaaa atgactttat agaaataaaa gatactgaca ttgtttatca gggcttttcc
    15601 gtttcctttg atatgtggtg tgaagaggta tggatcagtc tttttgccgg agcaaccatc
    15661 tggattgctg atgctacgac tgtaaaagca attgatgagc tcagccatgt tttgacagaa
    15721 aataaaatca cggtgcttca tgcggttcct agtattttag ccattattga tgaagtccct
    15781 tccatcaggt ttattaatac cggtggagag gcctgcacca aacaggttca ggaaaagtgg
    15841 gcaaaacctt acaggatttt tatcaatagc tatggtccta ctgaaactac cgtttcatcc
    15901 aatatgatca aactcaataa tcaggacgaa cttacaattg gacctccgct acccaattat
    15961 catattgctg ttgttgatga aaatatgaat atcctcccaa gaggagaacg tggtgaaatg
    16021 gttatttccg gaccaggcgt gagcaatggt tattttaacc ttccggaact tacagagcaa
    16081 aagtttttgc ccaacccttt tccagagctt cccggagaca aaatttataa aaccggcgac
    16141 gctgttacca tacgggaaga tggatttatt gattttcagg gaagaataga tgatcagatt
    16201 aaacttcggg ggtacaggat tgaacttggt gagatagaaa cacgtatgaa tcagcttcag
    16261 gacgtttctt ctgttgctgt atcagtaaaa gaagatgcta acgggcaagg gcagcttgtt
    16321 ggttatgttg ttatgagtaa tgaagcatca tttgatgaaa ataaaatgag aaaagaactg
    16381 gcacaatttc ttgctcccta tatggtacct atttctatta ttcagatgaa agaaatgcca
    16441 aggatgccca gtggaaaaat cgacagaaaa cgacttccaa tcccggaaag ctttacagtt
    16501 cataaaaaaa atgataacat taagattaat attgaagcac ctatagaaga aagattactg
    16561 cagacgctga aatgggtatt tccaggaaag gaaattaacc tgcaacagga ttttttcact
    16621 gatttaggag gtcattctct gcttgcagcc actttagtct cacatttacg gcaaaaagca
    16681 ggaatcccta cagcttcatt aaaagaaatt tatgaaaatc gtcctttatc tgcctactca
    16741 gactgcctca agaagaaaca agctcagaaa ccatcacatc atgaaccgtt ccaccgggtt
    16801 tcaaccttac aatatattgc ctgtaatatt gcccagacta taagtttgct ggttgtgttt
    16861 gccctgttga gtattcagat atttttccct tatttaagtt attattattt tcagcttaac
    16921 ggctatggat tacattatgc tttattaagc gccttcttac tgtatacctt aattccacca
    16981 gtgtattctc ttattatcgt tttaaccaaa tggctggtga tcggaaaaat caaagaaggt
    17041 gattacccgc tttggggttg gtattatttc agatggtggc tatggaaaac aataaaaaga
    17101 ttgatgcctt cggaatttat cgtagaaaca cctttatatc caaaatattt gaaattgctt
    17161 ggagtaaaag tgcatccaag tgctcaactg agtttactcc ctatcgccgc agaggatctt
    17221 gtaaccattg atgaaaatgt aaataccagt tccggatgca gtattgacaa cgcttctgtt
    17281 gaaaatggta ttttaagaat aagaaaagtg cacattaagg cccattctta tctgggttct
    17341 tctgtaattg tatgtgggga tacagttatt gaagagtttg gagaacttca ggatttaagc
    17401 tgtctgaatg aaggaaaaaa aataggatat ggagaagtct ggaatggaag ccctgccgaa
    17461 aaagtaagaa taaaaacagg agcagaactt gaagctccta agctatcatc agcttccaag
    17521 agaaacagat acgcattact atattcaatt tctttattct tctttccact tctgatcgtg
    17581 ttaccgctag cccctacact ttatacatta tattacctgg atgaccgctc ctctgactat
    17641 agtttttatt atctatggca ggctccgata ctttctactg tttatatttt actgtttatt
    17701 gctgttgtaa gtatccttac aaggatttta caatataata tgaaacccgg agtctatcct
    17761 gtatacagtt tcacctatta tagaaaatgg atcaaggatc aaattttcaa cctatcactg
    17821 attatcgtac atcctttatt tgcttcaatt tatattagta aattttacag aatgatgggg
    17881 gcaaaagtgg gtaaaaattc agaaatttca acggccagcg atgtttcaca tcaccttttg
    17941 gaaattggtg aaggttcatt tattgctgat gctgttattt taggtgaaca tgatgtaaga
    18001 aatgaaaaat taattttatc taaaaccact ataggaaata atagctttgt agggaacagt
    18061 ggacttattc cacaaggata tgaattagga gataatatgc taattggtgt tttgagtaaa
    18121 gcaccctctg aagaacagct caaaaacgcc tctgagagag actggttcgg atctccgcca
    18181 ataggtcttc cttcgagaca gaaatcggat ctatttcagg atcgccttac ctacaatcct
    18241 cctttccgtc taaaactggc aagagcaatt gtagaaggaa tcaggattat ccttccacaa
    18301 accgtagtta ttatatgtag tgtattattt attgcttata caagcactta cttggaagga
    18361 agaatccatt atcttttatt gtttgctcca ttttattatc tgggaatcgt tgcattacct
    18421 tcatttttct ttactgcatt attaaaatgg atatttatag gaaaatataa gaaaaccgaa
    18481 atgcccatgt acagtctgaa agtatggctt agtgaaggaa ttactacaat ttacgaagct
    18541 cttccagtac ttttcttcct tgattttctt cgtggtacat ggtggttacc gttctttatg
    18601 cgctttctgg gtgttaaaat tggtaaaaaa gtatggctta acaccactga tattacagag
    18661 tttgacatgg tatccattgg tgatgaatct atgctaaatg aagactgcgg acctcaaacc
    18721 catctttttg aagacaggat catgaaagtg ggaagtgtaa aaatcggaag tcaaaccact
    18781 atcaattcca gaacaattat tttatacgat accgaaattg gggataatgt taatattgct
    18841 cctctttccc tcgtgatgaa aggagaaatt ctttcggata atacttcgtg gctgggaagt
    18901 ccgttgagag gaaaataatt aattaaggac ttccagatct aatccataaa ataaaatact
    18961 attatgaatt attccatcaa aaaaattaaa ataaaagaaa atttgtctat tgtagatgaa
    19021 ttagtaggcg aacttcatat ttctgaaaaa gaaatgaatg agaatactgc agactggagc
    19081 cagatccggg ataattatct cagatttatg gcagaatgtg aggaagaaaa tgagggaagt
    19141 tttctcattg cagaaattga tggtaaggcc ataggatttc tgttcggata tattgatgaa
    19201 agagatgaaa gtaattttga attgggagaa ggcaacgatc tctatgtttc tgagggttat
    19261 gtaaaaaaag aatacagaaa acaaggaatt tacaccgcgc ttaataaaac atttgaagaa
    19321 atgtattcta agcgtaacat ccgaaaaata tatcgcttta ctctttgcaa caatgatacg
    19381 atgcagcgtt ggctggcttc gcaaggatat cgtcctgtaa ggatagtgta tgaaaaatgg
    19441 ctataatgaa agactgaaaa gagaggaaaa ccaatagctt tactcttcgg aaaagcattg
    19501 tagtcgatta tattacaatc tcatttaaaa taaaaatctg gtaagaaaac ctaccagatt
    19561 ttgcacgaac actgttcttt atttttgtct gaagtatact tcaatcggaa ctccggtaaa
    19621 cccgaattct tttctcaact gattttcagt aaatctctta tatggctcct ttacatactg
    19681 cggcagatta cagaagaata caaactgtgg tgacggcgta ggaagctgga cgcaatattt
    19741 aattttaata tattttcctt ttaacgcagg tggtggcgta ttctcgaaaa taggaagcat
    19801 tacttcattc agttttgaag ttttgatctt cttcttacgg tcttcataaa cctccattgc
    19861 aacttccact gcttttagga ttctttgctt cgtcaatgca gaaacgaata gaattggaat
    19921 atcctgaaac tgaccaattt tatctttgat tgctttttcg aaatcacgca ttgtattggt
    19981 ttgcttgtct tcaatcaaat cccacttatt caccagaatt acaattcctt ttctgttttt
    20041 ctgtgctaat ccgaagatat tcatgtcctg agactcccat ccctgagtag catctaccat
    20101 aatgataaca acatcagaat attcaataga acggatagat ctcattacgg aatagaattc
    20161 caggtcttca tttactttag actttcttct cattccggct gtatctacca atacaaactc
    20221 atgcccgaat ttattataca gcgtctggat actatctctt gtagttcctg cgatatctgt
    20281 tacaatattt ctttcaacat ctaataaggc attggtcatt gtagactttc ctacattcgg
    20341 acgacctgcg atggtaattt taggtaggcc ttcgaaagga tctttatatt ctgtagttgg
    20401 gaaatcttta acgatatcat ccagtaaatc tccagttcca gaacctgtag cggaagaaag
    20461 agtgtaatat ttatcgattc ctaactggta aaactctgtt gcaggaagtt cttcttttga
    20521 tgaatctact ttgttaatta cgatatagat tggcttgttt gatctcctaa gcagtctgta
    20581 aatttcgtgg tcagtatcgg taagcccttc ttccacattc atcataaaga taatggaagt
    20641 agcttcatct actgctaact gtacctgctt acggatctcc tcttcaaaga tgtcatctgt
    20701 acctacatca tatcctccgg tatcaattac ggtaaagtct actccattcc agtcagattt
    20761 cccgtaatga cggtctctgg ttacaccggc tgtagaatct acaatagctt ctcttctttc
    20821 taatagacgg ttaaaaagtg tggattttcc tacgttggga cgtccaacga ttgcgacaat
    20881 atttgacata aaaaatattt aataatcctt tgctgcgcta aggatatgtt attaatgggt
    20941 tactccaact tttggagccc aatttttttg caaagatagg attttattat ttaggattaa
    21001 aaaccttctt ggttttgaac attccaagtg aaaaataatt atttggctat cagcaaataa
    21061 gcccataaac actcgattat gtttactttt ttttaatttg aagttttgta gttcaaataa
    21121 tttttctaat tttgcatcat caaaacagac ccatggtgta gcggtaacac tactgatttt
    21181 ggttcagtca tctggggttc gaatccctgt gggtctacat tgaatataag caatcttctg
    21241 attatcggaa gattgctttt tgttttatct ttgttttcat aaaaaagata tctactatca
    21301 ttgtgtgata tctaatctta tttataggta cataacagca gttttctacc ttcaaaacga
    21361 acagccatta gactctttgc tagtagaagt ctattattta aattaaattt ttcttgtcat
    21421 aaaataaaaa tttctattcc tctactcttc ttcttaataa cttaaggatt tttagaaaaa
    21481 tcagtaatct aaattttaat acgacatagt ttgacgctat gctgtagtag atttgcctaa
    21541 gaatgatatg gagctacaac gtgtaatgaa atatcctcat atttagaaat atcttacatt
    21601 aaatcgcatg tatgtgattt gcgtaaataa aaaaagttaa atttgtacga ttttaaaaaa
    21661 gctaatcatt aaactcaaaa aacacgggaa tgaaaaaaat ctatctcagt gcatgtactg
    21721 tatgcaccgt tcttgggctg tctgcccagg aaattctgtg gcagaaagac atcagatcct
    21781 ccactcagga ttttctaagc caggtgacta ccacgattga tcagcaatat ctgattacgg
    21841 ggagttctat acagagcggc aaactccaac cgggccgcca acaaaacaac ggttatgatt
    21901 tccatctggt gaagctgaac cagcagggag aagaagcctg ggaaaagtat ttctcaggaa
    21961 acaatcacga ttatttatca gcaacagtct ctactcagga cggtggattt cttgtagccg
    22021 gaacctctta ttcaggaaaa ggactggata agaaagagga ttccaaaggt ggatcagata
    22081 tctggctgat caggatcaat gaatttggag atgaattatg gcagaaaaca ttaggaacct
    22141 cttctgatga agaagccaaa gccgtgattc aaagtacaga cctgggcttt tttgtggccg
    22201 gaaacgtcca aaactcatct caaggttacg gttctaaaga tgtctggatc accagactcg
    22261 acaaagatgg caatgaactc tcccaactga ttttaggtgg aaaaggcctg gatgaaattg
    22321 aaaagatgat tcccacaaaa gatggtgggg ccttattggg aatttattca agaagttccg
    22381 aggtccgtgt ttcgggaggt tccgggatgc gagatgcggg ttccgtgtca gccgttcaaa
    22441 actcgaatcc cgaccctcgg aacacaaacc ccgtatcccg catctcgaaa caaagcgaaa
    22501 acttcggaga aggcgactac tggattgtca aactggataa aaccggaaaa gtagaatggg
    22561 aaaagaactt cgggggtaaa ggagatgatc atatcagaat gttggcccta acatctaacg
    22621 gttatatcat cggtggagag tcccgctctg aaagatccgg aaacaaaacg gtagggattg
    22681 aagaaggaac agacctttgg ctgatttccc taaatgaaag aggtgaagaa cagtggcaga
    22741 agtcctacaa ctttaaaaac agggatattt tgatgggaat gagcgtaatt cattcttcag
    22801 atgataagtc ttcaaaagga attctgttag gtggttacac tcaggcagag ggtaggatag
    22861 aaaaagatga tgagaccttc tggatgctgt acctggatgg taacggaaat gaacagtgga
    22921 gaaaacatgt gacaggcgaa tccagacaga aagaagaaag gctttcagac ttgaagctaa
    22981 accgtgatgg ctccataatc cttgccggaa cgagtgctaa ggaacttgga aaagaaaact
    23041 ggaaaattgt aaaactgggg gacaagcagg tgagtgatct gattgccaaa tatgatatca
    23101 agatttatcc gaatccggta tcagactatg cctatgtaga aattggcttt gattttaaag
    23161 aagctgatat tatgctgtat gatatgagcg gaagacagct tcagaatttt aaaacaaaga
    23221 atagggtgac taagatgaat actcaatctt tgatacaggg agcgtatttg gtgacgataa
    23281 aaacagataa taataaaaca gcgaatgcaa agctgattaa gaaataaaaa aacattaatc
    23341 atgaagaaaa tatatagatt aatagtaagt agtatgttta tactctatgg tgcgcttgtt
    23401 atagctcaag ataataataa cagcatacag aagaaaaata tagtagcttt tcctacgtca
    23461 gccaatgcat atgctataga taaagtagga aaactggctg ttgatatgtt taagggaaaa
    23521 gcaaatatca atattccttt ttatacaata aacgtagatg gagtgagtat tccgatctca
    23581 ctttcttata atacaggagg tataaagtta aatgagattg caagtactgt tgggctaggt
    23641 tggtcattaa atattcctag taatatcagc cagaatataa tcgataaaga tgataaaacg
    23701 ttttcgatgt ataccaaaga tattaatgtt gttaattcta attttagaag tgtcggaatc
    23761 tatgataatg acattcgtca gataattgat gatcattatg aaggaatcta tgatacaaga
    23821 cctgaccttt ttaattactc gctacccttc ggagggggaa gctttatttt caataatgac
    23881 ataggatata ctattcctca tgaggacctt atgattacag gtacaaataa taaaaagaat
    23941 attaaaattg taaatactga tggagctatt tattttttaa gtattaaaaa taatacatca
    24001 atggattcaa acataccggg aagtactaca tcttcgtctg aaactttata tcagattgat
    24061 agtataagaa caatcactaa taagaaaatt ttatttgaat ataccaaaag ctattattat
    24121 tcagaaaaga gtataacaga aagggctaat attgatatta gtgacgaagt aagttcttct
    24181 gcagatttac ccataaacct tcctaattac gaaagatatg taggtacaat aggaaataga
    24241 gaaaagctca taacaaaaat tatttttcct gaaggaactg tttattttaa ctactcaaat
    24301 gacggattcc ctttttctga tggcacaagt ataagaaaag acattttgtc aaatgatggt
    24361 gtcgcattaa ggcaaattct tgtaaaggat aaatatggta aaataattaa agattataat
    24421 ttaaatttct cttattttac ttccaactca ggaacagatt accaaaatta tagattaaaa
    24481 ctgcttaata tctatgatag ccttcagaag aattattata aattctatta taacgaaaat
    24541 ataccttttc ctgccagaaa ttctaataat gatgattact gggggtatat taattcaaca
    24601 acgtattctg agaactctac aaatatccca gataaaatct atacagatta cacttctaaa
    24661 aatattacac ttcctgctca gtatacaaga aacagagata caaaccccga ctacacatca
    24721 ataggaattt taaacagaat tgaatatcct acaggaggaa gtaaatatct gtattatgaa
    24781 aatgctacta aattttttac tagaacaaat tatcaatggg ggtacactga taattttgcc
    24841 actgttatga gccagccaag tggaaatggc ggttcaagtg ataattttgg taatattagc
    24901 cagacaatta ctataccacc tacttatttt gacggaaaag agtctccaaa gattaagtta
    24961 atatttggaa atacatgtga aaataatgta gatgacgaaa caagtcagat tcatgatact
    25021 tcatgctatg ggaatgcaac ttctaacggg gggtattatg gaacaaatgg taagcctgct
    25081 gtttttgagc tgaataatgt aaatagtcca attaatattt cactgtccag aacaggtaaa
    25141 tgctcatgcg gatatgctgt agatgttgtt tatgggcaat atacaacaat aaactcaaat
    25201 attccgattg gggggcttag aattaaaaaa ataaaggatc tggataataa cagttttgtt
    25261 aatacttata attataaata tgatgtttta gataaagcta caaatactta caaaagtagt
    25321 ggtattttga atatgccttt ccaatataca accttgctga agagatatgt aacacaggct
    25381 ataggtggag gagagttagc ttatccttat atccagaagt atttagtagt taataattcc
    25441 agtactaatt ataattcata cggttcttca gatgtactta cctataagca ggtaactgaa
    25501 tataatgaac taggacaaaa tattaatatt ttttcccaga tcaataattc agatagtgat
    25561 aaaatgtata ctcatgttta ttcaaattat aatgattgga aaaatggatt gctggaaaaa
    25621 aatatcatac ttaataaatt aaatgatact atgaaggtaa caactcataa atatgcattt
    25681 aattatttaa aaaacccaaa agcaggcttt attacaggta catctgatca aataggtttt
    25741 gctttaaatt tggatattgt aaaatattta aaaagggtaa ctgttgttaa tgaaaatccg
    25801 atatatgtaa atatatatcc agtaactaaa gaaatcattg gaatcaattc tgcaaaatta
    25861 gagcatatag aaactacaac aaaagaattt tttggagata aatctgttgt cactaaagta
    25921 ttaaataatt attgggatac tgatattaat aaacctttta atgtaaaaag cactgaaaat
    25981 atttttcctt ctggtgaaag tgtaaaaaca gagtatcagt acgctcatca gaccggaaac
    26041 caactgttaa ttgataaaaa tatgattgcc accccattgg agacagaaac cagacaaacg
    26101 attaatggag ttaccaatgt attatcaaaa tccaaaacca tttatccaac tgcgcttccc
    26161 acttcccaga ccggaaattt agcacttccc atgtcaattt tgtcctatga tatccagaat
    26221 ccttcagtag tggctaatga agtaatctat gataagtacg attctaaggg aaatattgtg
    26281 cagtatacca ccaaagatgg cgtttcaaca gtcattatct ggggatataa cggaacgcag
    26341 cctattgcca agattgaaaa tgccaaactg gaaaacattt cacaatcatt catagacagc
    26401 attgtgaatg cctctaatac agatgcttct gccgaaagaa ataacgatga gaccaattta
    26461 ttaaacgctt ttaatacttt taagaataat ttgtccggtt atcagatcac aacttattct
    26521 tacgatccat taattggagt tcgaagcatt acgcccccct ccggcatccg ggaagtttac
    26581 ctttatgatg cagctggcag gcttaaagaa gtccgagaaa acaaccagac cggaaaactg
    26641 ttaaaagaat tcaactatca ttataaaaac taacaccgat gaaaaaaatc ataattccca
    26701 taggcatgtt gctgctgagt tcttcagtcc atgcccagct tagtccggga gaaaactata
    26761 tccaatccaa aacctatctc gattataatg gaaccactcc aaccaaaacc tcagaaaccg
    26821 tccagtattt tgacggtctg ggaagaccca aacaggtagt gaatgtaaaa gcatccccac
    26881 agggcaaaga cgtagccgtt cctattgagt atgaccagtt tggaagacag gtgaaagact
    26941 atctccccat tccccagtca ggaaccctga atggaggaat tattcccaat cccttatcca
    27001 acgcttcaaa tactccttat ggttccgaaa agatctattc cgagaagata ttggaaaact
    27061 ctccattgaa caggattcag cagcagatcc aggtggggaa tgactggagt accaagcctg
    27121 tgaagtttga ctatcaggcc aatggattga atgaagtgtc ccggtatatc accacaacca
    27181 cctgggaaaa caatgctacc aaaagtacgg taagtttatc tcaggctgcg gtgtatgctc
    27241 ccggtacttt atataaaaat accattactg atgaagatgg aaatcaaacc ttagaattta
    27301 aaaatgggaa agggcaaacc attctggtaa gaaaactcat gggctacatg gaacaagccg
    27361 atacctatta tgtatataat gaatatgacc agttggcctt tgtaattcca cccaatgctg
    27421 ttcagcagcc tattacagat gttctgctca atgatctgtg ctatcagtac cgttacagtg
    27481 ggaggaacct tcttgtcgag aaaaagcttc ctggtaaagg ctgggagtat atggtgtatg
    27541 accgccagga caggctcatt gccactcagg atgccaatca gagacctgct aacaactggt
    27601 cttatacccg ttatgaccag tttggaagag tggtgtatac cggaattgct actgattatg
    27661 ccaccagggc cacattacag caatatgtct ataacaaagg ctataatact tccaataata
    27721 ccaccagaac cccctctccg tccttcaggt taagtgggat ggatatttat tataccaatg
    27781 atgctattcc tgaagtattg aataacgttc tgaccgttac ctattatgat acctatcctg
    27841 cttatagctt taatccatca tttccatcag cgatccaggg agtagatacc ttaaaagaca
    27901 cagtatcccc tgaagggaaa agtaccaaag gattaccggt gatgagcctg gttaagaata
    27961 tagaagatga taagtggacc cgtaattata cctattatga taccaaagga agagtaattg
    28021 gaactcattc gatcaatcat ttgggaggat acacccggac agaatccagc ctggactttg
    28081 caggcgttgc tcaaacggtt atcaccaggc ataagaggtt agaaaccgat accgaaaggg
    28141 tgatcacaga aacctttacc tatgaccatc aaaacagatt gctcgtgcac aaacaccagg
    28201 tagatgccaa tcctgtagaa atcctgaccc agaataccta taatgaactt tcccagctgg
    28261 aatctaagaa agtaggaggg attgctgtag gatcttctct tcagcaaatg gattatcaat
    28321 acaatatccg tgggtggctc acgaagatta atgacccttc caacctgaat gggaaattat
    28381 ttggctatgg aataaaatac aataatccat taaactctgc aaaatcacta ggtaggttta
    28441 atggaaatat tgcagaagta gactggagaa attcatcaga agaggttctg aaaagataca
    28501 attatgaata tgataccctg aaccgattaa aaaacggctt ctactcagaa cctaatgcga
    28561 ccaatccaga taatggtaat tttgatgaat atcttaccta tgatgtgaac gggaatatca
    28621 ataccttgaa gagaaaagcg attcctgtat caggaggaac gtctacttta gtagataatc
    28681 ttgaatataa atacaccgga aaccgtttaa atcaggtgat agaattagca atgaatgata
    28741 cagggtatga aggtggaaat aatatgattg actatgatgt gaatggaaat atgaccacta
    28801 tgaaggataa aaatattaat tctattggct ataattatct taatttaccc aatcagcttt
    28861 ttataaatca gaagttttcg ggatggaatc ataatactaa tataacacat ctgtatcgtg
    28921 cagatggatt aaaacttaga acaactaagt atagtgcaat agatggggat ataggagata
    28981 ccactattac tgattatctg gatggttttc aatatcgtta ctatgataat ggattaatgg
    29041 gaggaccttt attacaggat aaaacaagtt ttgcttatga agatcaggct tatacgaaaa
    29101 caggttcaat gtttccttct aaaccgaagt ggcagttaga ctttgtacct acttcagaag
    29161 ggttttacag tttcacagaa aaccgctata tttaccagta taaagatcac ttaggaaata
    29221 cgagaataag ttttgcaaaa aatagcgcag gagttcttga agttacagat accaataatt
    29281 attatccttt tggactaaat catatcggag gaattaaagg gcagttaggt agttataaga
    29341 attacaagta caacggaaag gagctacagg aaactgggat gtatgattat ggggcgagaa
    29401 tgtatatgcc ggatatcgga agatggggag tgattgatcc tttagcagaa aagatgacac
    29461 gatttagccc ttataactat gcatttaata atccaattag atttattgat ccagatggca
    29521 gacaaaataa agatgtaatt attacaggtg attacaaaga taaaactatt gaactattgc
    29581 aagcatctgt agaaggtcag ttaaatttga caatggataa aagtggtaaa gttacagcta
    29641 cagctgtaga aggtgtagaa ctgacagagg cagcttcaac attcttacaa gcaacgcagg
    29701 ataattgtaa tatagttgtt ttaaaaacag atggagatta taggcttgat gatggttcat
    29761 tttatcaagg tggcgcctac ggaggaagca aaatggcagg aaatggaaaa atgataggaa
    29821 ctaatgttgt aaaccctatg gttagcgaaa agatagatga agcattaggt ttaccaaaag
    29881 gagttggagt gttacatgaa ggtcttgaga attatatggg tatattaaat agcccaggta
    29941 gccccgcagg aacacctgaa aataaagata aaggttatat ggctgctcat aaaaaagcta
    30001 atgaactaga tccgagacac aaggatcctg ggaaggagta tagtagtgaa catataaagc
    30061 aaaatataaa aaatactgat ggtaaaaaat tatatactca agaggaactt atttacatca
    30121 ataataaaac aaatgtaaga acgtctgtag ggcgttttaa aaccaaccca taatgaaaaa
    30181 attaatttta atctgtgttt tatcatctat taatacatac agccagcaag aaaataaagt
    30241 caatgtaatt gcaaaagtta ttaaaataga ctctactaaa agtagtttta taatctatat
    30301 aaaaagtaaa tctggacaag gtatattttc tattcctaaa atttgtaata atcaaactaa
    30361 ttacaaattc aaaatagaga aagacaaatc atattttttt acattaaaaa aggaaataca
    30421 taaacatatg ccagaaaact taacgcaaga gttggttgaa acagaattag tagatgataa
    30481 agtggtttgg tctagcaaaa tggatagtac cttctatgaa gattgtacaa atatgtgtgg
    30541 tctatatatt gataatgaag gaaaacctaa acaaaataga agtagcaaaa aaaaatggtt
    30601 gaagaaaaaa cattgacagt ttataccccc ccccgctggc gcgagcgtct cgctcgtgtc
    30661 cacaaataaa acgaaactat attaacaaca gtgttgatct ctccgctccc gcacgattgt
    30721 atcgtgtggc agataataaa aaaccctcgc aaattgcgag ggttttgtgt ttataaagca
    30781 actacatttt tattaaagaa atccttaaac tttttagtag taagcatttt atccaccatt
    30841 ttaaaaatca tagacttatc ctcttcatca agctgattaa tcagatgcag cttctcaaag
    30901 tccggtttat cctctatggt tacttcttca ggaataatat tttcatagtt caggatctga
    30961 tctgtagtca gattaaaaag ccttgaaagc ttcaggagtt cctctacaga taactctcta
    31021 tgaccatttt ccagcttatt ataattgctg ttgccaatgc cgagatgtgc agaaacctct
    31081 ttctgcataa gccctttatc ttcccttatt tttttgatga ttcttccgat actcataatg
    31141 atgatataat acaattgtat tatacacaaa tgtagttaaa agtgtgaaaa aggaaaatac
    31201 ttgcgaaata ataaaaatac attattcgat tttagaaatt aattttaaga tttgtaattg
    31261 aaaaaatcgc acaaaataat tttttctatg gaaatccaag caatcaaaga gcatttacac
    31321 ctgtctgaag ttctacagca ttacaatctg cactcaaaaa acaatatgct tttatgtccc
    31381 tggcatgatg ataaaagagc aagtttacag gtgaatctgg aaaaagattt ttacaaatgc
    31441 catgcatgcg gaaagacggg tgatgttatc tagtttatag aagactatga gaagcttacc
    31501 aaacacgaag cgataaagaa agctgaatca ttgattaatc ctgaaatatc catattgata
    31561 aaacctaaaa ctaccgaaga taaaacccac cacttgcatt ttgaattaaa tatcccgccc
    31621 gccaccagaa aaagacattt ttctccaacg cttgcctaaa cttcccttaa gctttaatgc
    31681 cacagcaaat tacataataa aatgctttcc tttgtagcgt caccacaata gtaaacggat
    31741 cttattaata aaaagcacct acatttctgt aagtgctttg ttaatgttat ttttactaaa
    31801 atattaaatg ttaatttcca tcataggtta ttacccagtt catatttttc aaatcctgta
    31861 atgtaagatc atatcgtttt aaaacgagat tatttgcttt aatatactcc caccccttgg
    31921 tttctaacgt agatccatca aaaatgtaga ccatcataac accagatggt attaaagaat
    31981 gatacacatt ttcatacgaa gttttagatg ataatacagt ttgtgtggtc tgatctgctt
    32041 caaccttatt atatcccccc agcttaggat cagggttttg tttatacact tctgtatcag
    32101 gatattcata ggaacttagt atgtacaaag ttttattggt tttgttgaca aaagttatga
    32161 cctgatggct attttcagtg ttgctgtata cacaagaaac aagcattatc attgtactta
    32221 gcagaagaat aacatttttc ataaagttta tcatttatta ataaaataat tagaaattcc
    32281 tgaaatcgca taccctgaag ttgcaaataa tacagcatca taccacttta gatgagtaag
    32341 attactggac agggccattt gatttgaaat atcgttaaaa gatttagacc aatcatatcc
    32401 tacgattaca tttcttctat cccagccgtt ataattttca acatgtttat taaaataggt
    32461 gaaagccctt gaattagcat cctgttctgc ataatgtaaa gtatgattat ttttgcttaa
    32521 tgtatcaaaa aaacttggta ttgcaaactt ttgcatatag aacaacccaa atttctggct
    32581 ttgtaaataa tgaccatact catgctggaa taaactgttg ttaggatctg cctgtaaacc
    32641 tctatcacca attataaagt ttccaagtgt aaaccctccc cagtttggtt tataagattc
    32701 taccgctgtt gcaccatcat agtaagtaac actttttacc cctccgaaga gattatagaa
    32761 ccctgaggaa aggtatccta acattgactg atcagactcc catgtaaatc ggctcagtat
    32821 ctgtccgaaa ttacctttaa ataagcccat atcaattttc caggcttttg aagttctact
    32881 gtaatcataa tcaccaaaat taacgccatg agtgaaaata tttttaaatg tatcaaaaat
    32941 agccgtaata aatgaaaaca gttctccact tggatctgta tatgctaacg gattattcag
    33001 cacatatcca tatcgattat aattctgggt attaaaagga tcctgaatat agttatctac
    33061 agaaaggaaa gtgtgcagtt tcggatcata cattcttccg ttcatatgta tcaacccaac
    33121 ctgaaagaaa tgctcatgcc ctgtataacc acgctcaatc attaaatcag gagcttgttt
    33181 gtttaaatta attaccgttc cgttcttttc taaatagaca agatttcccc atgggtcaaa
    33241 atgtcttcgt tcttcaacat tacccttctg atccgaaatt gctaaaatag tcgactggta
    33301 atctctatga agataatgta ttccttcgct caatagatcc atattaacat taaaatcttt
    33361 gatataaaca gctggagcag tataaggatc attagcaata taagtgatga tccgcatccc
    33421 taatgcatta acatttggct ttcctaaata attgtaatta ataatctcaa cagagctatc
    33481 atcagaatag atttttcctt ttccatatac aaaaaaatca ctataaaaat cctgatctga
    33541 agccgacctc ctttgatgga tattatactt aaagtgagcc atttcgtatc cttcctgttt
    33601 tattacagtt ggcattctgt acgaattata ctctacttcc tgcagaggat ttgcactata
    33661 atatgcatca ccagcagaat tcagattaat ggtttctttt ctatatctgt taacgccatt
    33721 gtatttgtaa tcacccacat tgctattatt atctattctt ccgtaggcat cataggtctg
    33781 tgattgtgat ccgttgggat aggtccaagc cacaagtctt tgctgattat catattcgaa
    33841 attttctaac catcctccct ggatcaccgt attgtttctg ttttgcaaag taccggtcat
    33901 agcagaaaaa ttataaat
//
