LOCUS       NZ_CP120209            20222 bp    DNA     circular CON 19-MAY-2024
DEFINITION  Chryseobacterium indologenes strain Ery-6B chromosome, complete
            genome.
ACCESSION   NZ_CP120209
VERSION     NZ_CP120209.1
KEYWORDS    RefSeq.
SOURCE      Chryseobacterium indologenes
  ORGANISM  Chryseobacterium indologenes
            Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
            Weeksellaceae; Chryseobacterium group; Chryseobacterium.
REFERENCE   1  (bases 1 to 5246911)
  AUTHORS   Xu,S.
  TITLE     Synergistic degradation of erythromycin by symbiotic bacteria Ery-6A
            and Ery-6B and application in simulated water remediation
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5246911)
  AUTHORS   Xu,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-FEB-2023) Zhejiang Agriculture and Forestry
            University, School of Environment and Resources, East Lake Campus of
            Zhejiang A&F University, Hangzhou City, Zhejiang Province, Hangzhou
            311300, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. DEC-2022
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: HiFiasm/Unicycler/Flye
            Genome Coverage                   :: 181.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_029339075.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 05:09:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,739
            CDSs (total)                      :: 4,629
            Genes (coding)                    :: 4,609
            CDSs (with protein)               :: 4,609
            Genes (RNA)                       :: 110
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 20
            CDSs (without protein)            :: 20
            Pseudo Genes (ambiguous residues) :: 0 of 20
            Pseudo Genes (frameshifted)       :: 8 of 20
            Pseudo Genes (incomplete)         :: 12 of 20
            Pseudo Genes (internal stop)      :: 4 of 20
            Pseudo Genes (multiple problems)  :: 3 of 20
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:37:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1878486
            Orig. end                         :: 1898708
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP120209.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20222
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="microviridin"
                     /region_number="5"
                     /rules="(mvd or mvnA)"
                     /tool="antismash"
     cand_cluster    1..20222
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(mvd or mvnA)"
                     /kind="single"
                     /product="microviridin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20222
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10222](-)"
                     /cutoff="20000"
                     /detection_rule="(mvd or mvnA)"
                     /neighbourhood="10000"
                     /product="microviridin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10222)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(mvd or mvnA)"
                     /neighbourhood="10000"
                     /product="microviridin"
                     /protocluster_number="1"
     gene            complement(616..1167)
                     /locus_tag="PYS58_RS08425"
                     /old_locus_tag="PYS58_08425"
     CDS             complement(616..1167)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002977603.1"
                     /locus_tag="PYS58_RS08425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08425"
                     /product="DUF1543 domain-containing protein"
                     /protein_id="WP_276285117.1"
                     /transl_table=11
                     /translation="MKLFYVILGATPKGRNIEQHDVFFGIAESLKDLIPDMKAFWKEAE
                     GKIHLDCYQEVRFADGYEVNIVDKSENTSENQLFFLNLGGYKPGFFEEFHEQHLMVGKS
                     MGEIVKRAKATEFYKTMGFEGAVSHIDDKHGVDIDDIFNVNDILPEAMKEKYSIVLTKS
                     DIENQENPMGLGYLKIDKIQ"
     gene            1265..2095
                     /locus_tag="PYS58_RS08430"
                     /old_locus_tag="PYS58_08430"
     CDS             1265..2095
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007844880.1"
                     /locus_tag="PYS58_RS08430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08430"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_276285118.1"
                     /transl_table=11
                     /translation="MSEIIILFFGAISAGLLGSLTGLGGGVIIIPLLTLGFGVPMHYAI
                     GASLISVIGTSSGAAVAFVKEGFTNMRIGMFLEIATTAGAIVGALVSGMLNPNTIGIIF
                     ASILLLTVALNLKGKPDHQEPLIHGSLEEKLKLYGTFPDKGILKSYSARNTVPGFLMMM
                     FAGAMSGLLGIGSGALKVLAMDNMMKLPFKVSTTTSNFMIGVTAVASALIYFQRGEIIP
                     VIAAPVLIGVVIGSFIGSKTLMVSKTKKLKVFFAIVITILSVYMMYNGINKSFR"
     gene            2095..2478
                     /locus_tag="PYS58_RS08435"
                     /old_locus_tag="PYS58_08435"
     CDS             2095..2478
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002977601.1"
                     /locus_tag="PYS58_RS08435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08435"
                     /product="DUF1634 domain-containing protein"
                     /protein_id="WP_185247563.1"
                     /transl_table=11
                     /translation="MKKNFTDVDLNRSVGNLLRLGVILSVATSLIGFIKLFTEGFEMPK
                     KYTSLVVGTSSEKVWGHFWNSLCKGEGMAIIQLGILLLIFTPLMRIIFALIGYLKEKDY
                     IYVFISSVVLAIMAVSFFAGYAH"
     gene            complement(2479..2856)
                     /locus_tag="PYS58_RS08440"
                     /old_locus_tag="PYS58_08440"
     CDS             complement(2479..2856)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009089563.1"
                     /locus_tag="PYS58_RS08440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08440"
                     /product="VOC family protein"
                     /protein_id="WP_185247562.1"
                     /transl_table=11
                     /translation="MKIHHIAIIGSDYEVSKRFYTETLGLQIVREVYREERQSYKLDLA
                     IGEHYVIELFSFPNPPARPSRPEACGLRHLAFSVENVAEKRNELTEKGLMCEEIRIDEF
                     TGKEFFFTQDPDQLPLEFYEM"
     gene            complement(3055..3495)
                     /locus_tag="PYS58_RS08445"
                     /old_locus_tag="PYS58_08445"
     CDS             complement(3055..3495)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007844883.1"
                     /locus_tag="PYS58_RS08445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08445"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_276285119.1"
                     /transl_table=11
                     /translation="MNKIAAILLVFSGFCFGQQNQEIEKPIHNLFLGMKNADPGLVKAA
                     FAEHAIMQTITNEGIIKTDNVPQFMAVVSKLTKDDLEERIMIEAVHVDGSLASVFTPYT
                     FYLKGKLTHCGANSFQLVKQNNEWKIQYIIDTRRKENCKEIK"
     misc_feature    3639..3654
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 24.22"
                     /tool="antismash"
     gene            complement(3707..4762)
                     /locus_tag="PYS58_RS08450"
                     /old_locus_tag="PYS58_08450"
     CDS             complement(3707..4762)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004918737.1"
                     /locus_tag="PYS58_RS08450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08450"
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="WP_276285120.1"
                     /transl_table=11
                     /translation="MTTQFIGKNNFAIHTQTVSESCPSNIALIKYWGKYDHQIPANPSI
                     SYTLNHCKTNTVMEFLADESFSVQTFLAGNEEVKFAEKIEKYFRNIEQYLPWILKGKYI
                     IRTENTFPHSSGIASSASGFGAIAKCLMALDETFTGKISEEESLRKASFLARLGSGSAC
                     RSLYNGLIVWGETEEVEGSSDLFAVPYPETEIHEVFKNFNDWVLLIHEGQKSVSSTVGH
                     GLMKTNPYAERRFQEARENFVPMKEILKSGDMERFIKLVEHEALTLHAMMMMSDPAFIL
                     MKSGTLEVINKIWDFRRETGLPLFFTLDAGANVHLLFPSGISEGQIITFIEAELLQHTQ
                     KNGVVKDVMRF"
     gene            complement(4792..6561)
                     /locus_tag="PYS58_RS08455"
                     /old_locus_tag="PYS58_08455"
     CDS             complement(4792..6561)
                     /NRPS_PKS="Domain: AMP-binding (9-460). E-value: 6.9e-99.
                     Score: 323.1. Matches aSDomain:
                     nrpspksdomains_PYS58_RS08455_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002977596.1"
                     /locus_tag="PYS58_RS08455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08455"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_276285121.1"
                     /sec_met_domain="AMP-binding (E-value: 5.2e-99, bitscore:
                     329.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLAEAIILKNVEKHPIKAAIGFKKKEEAWKELSWKKFSEIIFKT
                     ANALKEAGVQEGDKVAIYSDNSSEWMIMDLAAMAIGAITVPIYSTNNAEQAEYIIKDSG
                     AKVVLVGNQGQYDACLEFLHKEDNPLEIIIVSKKAVWIKKEFSSFYLEDFIAKASPKLE
                     ICKKEDEDTATLIYTSGTTGTPKGVMLTHGNFIKAFDSHFEFFKFKNFEEELSLAFLPL
                     SHVFERSWSLLCLYGGARVYFLEDPKNVAKALEEVKPTAMCAVPRFFQKVYAGVLEKAE
                     EGSSLKKKIFDWALKTGWETAELRRNEKAIPLGLKIKESIADMLVFSKIKNKMGGRLWF
                     LPCGGASLSPEVTRFFESVGIHVTVGYGLTETTATLTLFPLTHFEHATSGKPLPGVEIR
                     IGEGDEIQARGNGIMKGYYNRPDETQKVFTEDGWFKTGDAGKIDEKGNLIITDRLKDLM
                     KTSNGKYIAPQQIENLLTNNNFIQQIMLVAEGRQFVSALIVPNFEFLQDYIKKNNIPFT
                     NWEEVVKNEKVMNLYKEKIKELQSHLADYEKVKKFTLMPAEFDINTGEITPTLKVKRNV
                     VLKKYADIIEKMY"
     aSDomain        complement(5182..6534)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PYS58_RS08455_AMP-binding.1"
                     /evalue="6.90E-99"
                     /label="PYS58_RS08455_AMP-binding.1"
                     /locus_tag="PYS58_RS08455"
                     /protein_end="460"
                     /protein_start="9"
                     /score="323.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="KNVEKHPIKAAIGFKKKEEAWKELSWKKFSEIIFKTANALKEAGV
                     QEGDKVAIYSDNSSEWMIMDLAAMAIGAITVPIYSTNNAEQAEYIIKDSGAKVVLVGNQ
                     GQYDACLEFLHKEDNPLEIIIVSKKAVWIKKEFSSFYLEDFIAKASPKLEICKKEDEDT
                     ATLIYTSGTTGTPKGVMLTHGNFIKAFDSHFEFFKFKNFEEELSLAFLPLSHVFERSWS
                     LLCLYGGARVYFLEDPKNVAKALEEVKPTAMCAVPRFFQKVYAGVLEKAEEGSSLKKKI
                     FDWALKTGWETAELRRNEKAIPLGLKIKESIADMLVFSKIKNKMGGRLWFLPCGGASLS
                     PEVTRFFESVGIHVTVGYGLTETTATLTLFPLTHFEHATSGKPLPGVEIRIGEGDEIQA
                     RGNGIMKGYYNRPDETQKVFTEDGWFKTGDAGKIDEKGNLIITDRLKDLMKT"
     CDS_motif       complement(5278..5349)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PYS58_RS08455_0002"
                     /evalue="4.40E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="PYS58_RS08455"
                     /protein_end="428"
                     /protein_start="404"
                     /score="15.9"
                     /tool="antismash"
                     /translation="EIQARGNGIMKGYYNRPDETQKVF"
     CDS_motif       complement(5986..6045)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PYS58_RS08455_0001"
                     /evalue="2.10E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="PYS58_RS08455"
                     /protein_end="192"
                     /protein_start="172"
                     /score="29.4"
                     /tool="antismash"
                     /translation="ATLIYTSGTTGTPKGVMLTH"
     gene            complement(6558..7571)
                     /locus_tag="PYS58_RS08460"
                     /old_locus_tag="PYS58_08460"
     CDS             complement(6558..7571)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (3-190). E-value: 2.7e-28.
                     Score: 90.7. Matches aSDomain:
                     nrpspksdomains_PYS58_RS08460_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002977595.1"
                     /locus_tag="PYS58_RS08460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08460"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_185247558.1"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.2e-11,
                     bitscore: 41.5, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2e-08, bitscore:
                     31.8, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2.1e-26, bitscore:
                     90.7, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVFVTGATGILGRIIVLELLKRGKNVRASKRPGSNLNEVRHSYSF
                     YTENPDDFFNKIEWVNLDFDDIDSLKDALKGVDEVYHCAAKVSFHPQDEKEMYRTNIKG
                     TENLLYACEGSDVKKFLHVSSVAVLDNYNDKGELDEDSDFNPKLEHSAYAISKHLSEME
                     AWRASAEGMNVVIINPGMIVGSGNWTQSSGELFSTFEDNSFTFAGGSAYVDVRDVAKTA
                     IELMENNIFGERFIIVSENNRYADLAKQVRTRLGLKEARILTRSQLNIGKLANTLFGWL
                     IPKLRMATESNIEAISSFNTISNQKVREQLNYQFIPIHESIDFHLNNYINDKKLKK"
     aSDomain        complement(7002..7562)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PYS58_RS08460_NAD_binding_4.1"
                     /evalue="2.70E-28"
                     /label="PYS58_RS08460_NAD_binding_4.1"
                     /locus_tag="PYS58_RS08460"
                     /protein_end="190"
                     /protein_start="3"
                     /score="90.7"
                     /tool="antismash"
                     /translation="VTGATGILGRIIVLELLKRGKNVRASKRPGSNLNEVRHSYSFYTE
                     NPDDFFNKIEWVNLDFDDIDSLKDALKGVDEVYHCAAKVSFHPQDEKEMYRTNIKGTEN
                     LLYACEGSDVKKFLHVSSVAVLDNYNDKGELDEDSDFNPKLEHSAYAISKHLSEMEAWR
                     ASAEGMNVVIINPGMIVGSGNWTQ"
     gene            complement(7958..8962)
                     /locus_tag="PYS58_RS08465"
                     /old_locus_tag="PYS58_08465"
     CDS             complement(7958..8962)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002977594.1"
                     /locus_tag="PYS58_RS08465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08465"
                     /product="MvdD family ATP-grasp ribosomal peptide maturase"
                     /protein_id="WP_276285122.1"
                     /transl_table=11
                     /translation="MNKILIITHTADNFSIEKVTEYIKENNCEVIRFDVDLYPLQNKLS
                     TVFQDGTWVTVLETSEKKYRLDDISAVWYRRAYNIGKGLKDEMDAKFFAAAMGEIRNTL
                     FGFFESIDVYALGKPSVYRRLDSKEEQLKIAQKIGLTIPETCLTNNPEEAKRFILKHQN
                     VVAKMQTGFAIYENGIENVVFTNIVSEDKLEELDSLLYCPMQFQKMIQKKKELRVTIVG
                     RDVYAFEVDSQQYEDAKVDWRKDGVNLLDKWKQTALPADVKEKLLELLDIYNVDYGAID
                     IIVSPEDEYYFIEINAAGEFFWLDNLTEGNLISKSIADVLCDKAPRRDNMIMV"
     gene            complement(8955..9911)
                     /locus_tag="PYS58_RS08470"
                     /old_locus_tag="PYS58_08470"
     CDS             complement(8955..9911)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002977593.1"
                     /locus_tag="PYS58_RS08470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08470"
                     /product="MvdC/MvdD family ATP grasp protein"
                     /protein_id="WP_276285123.1"
                     /sec_met_domain="RimK (E-value: 5.6e-10, bitscore: 37.2,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILCITHSQDFYTIDRFFQHLSSKNIPYFRLNSDQLNHLRKISIS
                     EYSFEITDEEGNSIHSNDITGVWHRKAWPINVPEELDEEYEQIFRNEYASLRYNLFTQL
                     EHLPWINPYENEKKIDGNKMLQLKIAQQNKLIIPPTIFSNDEEKVKAFFDQQCSGKAIA
                     KLHGVARKTMSGQNLISTMIIEQETLDNLSDIIYCPMIFQPYIDKKYELRIMYVDGAFF
                     TGKINNSENADWRVSHEGYFWETYELPDDVKIKLTSMMKEMGLYTGAIDMIRGKDGIYY
                     FLEINPQGEWGMLQKELGFPIAERIADHLIKRINIHE"
     misc_feature    9960..9977
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: strong, score: 21.55"
                     /tool="antismash"
     gene            complement(10001..10222)
                     /locus_tag="PYS58_RS08475"
                     /old_locus_tag="PYS58_08475"
     CDS             complement(10001..10222)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     microviridin: mvd"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007844891.1"
                     /locus_tag="PYS58_RS08475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08475"
                     /product="microviridin/marinostatin family tricyclic
                     proteinase inhibitor"
                     /protein_id="WP_276285124.1"
                     /sec_met_domain="mvd (E-value: 1.4e-14, bitscore: 52.2,
                     seeds: 55, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKKSKKKPFFASFLEKQLKDPETVKGGTSIITIPERDVITKPI
                     IDDATSKLNDMEHTMKYPSDGDDDAAQL"
     gene            complement(10337..11116)
                     /locus_tag="PYS58_RS08480"
                     /old_locus_tag="PYS58_08480"
     CDS             complement(10337..11116)
                     /NRPS_PKS="Domain: Abhydrolase_1 (16-122). E-value:
                     6.9e-25. Score: 80.0. Matches aSDomain:
                     nrpspksdomains_PYS58_RS08480_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007844894.1"
                     /locus_tag="PYS58_RS08480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08480"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_276285125.1"
                     /sec_met_domain="PF00561 (E-value: 1.1e-19, bitscore: 69.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 7.2e-16, bitscore:
                     57.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEILNSKIFGEGSAATPLLVFHGLFGMLDNWGSFGKDLGEYLPVH
                     LIDLRNHGRSFHSDDMSHDDLADDIVRYMDHYGIQKAHVLGHSLGGKAVMQFAVKYPEK
                     VEKLIVVDISPKAYPPHHQGIIKALETVDFNTVGSRNEVEAVLNQYIPEKSTIQFLTKN
                     LYWDDDKKLNWRFNLKTLSEKYNEFVSNAIKFGVFEGDTLFIAGEKSNYILPQDEYGIK
                     QQFPKAKIVTIKNAGHWVQAENPADFAVVVKQFLGLS"
     aSDomain        complement(10751..11068)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PYS58_RS08480_Abhydrolase_1.1"
                     /evalue="6.90E-25"
                     /label="PYS58_RS08480_Abhydrolase_1.1"
                     /locus_tag="PYS58_RS08480"
                     /protein_end="122"
                     /protein_start="16"
                     /score="80.0"
                     /tool="antismash"
                     /translation="PLLVFHGLFGMLDNWGSFGKDLGEYLPVHLIDLRNHGRSFHSDDM
                     SHDDLADDIVRYMDHYGIQKAHVLGHSLGGKAVMQFAVKYPEKVEKLIVVDISPKAYPP
                     HH"
     gene            complement(11212..11934)
                     /locus_tag="PYS58_RS08485"
                     /old_locus_tag="PYS58_08485"
     CDS             complement(11212..11934)
                     /EC_number="2.6.99.2"
                     /GO_function="GO:0033856 - pyridoxine 5'-phosphate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014938323.1"
                     /locus_tag="PYS58_RS08485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08485"
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="WP_185247553.1"
                     /transl_table=11
                     /translation="MTKLSVNINKIATLRNARGGETPSVTEAAIKIQEFGGQGITIHPR
                     PDERHITRKDVYDLKPLVTTEFNIEGNPHQSFIDMVLDVKPEQVTLVPDADDAITSNAG
                     WDTKKHLDYLTEIIAEFKNAGIRTSIFLDPLPELVEYAAKTGADRIELYTEAYAKNYLS
                     DKEKAIKPYYDTAVVAHEFGLGINAGHDLSLENLKYFADTIPNLLEVSIGHALVSEALY
                     MGLENTVQSYLKRLAKWS"
     gene            complement(12080..13348)
                     /locus_tag="PYS58_RS08490"
                     /old_locus_tag="PYS58_08490"
     CDS             complement(12080..13348)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1234: transporter,
                     small conductance mechanosensitive"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002977588.1"
                     /locus_tag="PYS58_RS08490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08490"
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="WP_276285126.1"
                     /transl_table=11
                     /translation="MKDDLQDTKNYLQEISEQLYIYITQISPSGLDWVFHIIVKLALLC
                     AVFLIVDFVLKFSINAVFRLFHNENKFPVLKSIYQSKITNSVAHFAALTIVGGIQGSIF
                     PEGALPKTTIFIIRCVNLGLVMILAGMLYRSLTALRNYFSIKQDFYKIMALNAISETVK
                     ILGIFVFSVVGLCVVFGIKGTTIVGSLGAITAVLVLVFRDTILGFVTGIHVATSKNMKV
                     GDWISIPKYSIEGNITEISLLTTKITNFDKTVSTIPTYDFLTTEIKNMQIMSESNNRRI
                     KKSIYFNINSFKFLTDEDIERLKEINLIADYLEQKRVEIRREKESLSNNDKTINGRQLT
                     NIGVFRYYAQKYIENDPDIEKNATRMVRQLEITPQGLPLEVYCFANDSKWEHFEQIQAD
                     IFDHLLVASKEFELQVMQISIKV"
     gene            13524..14015
                     /locus_tag="PYS58_RS08495"
                     /old_locus_tag="PYS58_08495"
     CDS             13524..14015
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002977586.1"
                     /locus_tag="PYS58_RS08495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08495"
                     /product="DUF456 domain-containing protein"
                     /protein_id="WP_185247551.1"
                     /transl_table=11
                     /translation="MDTTVINILCLILLFVGILGTFLPVLPGLLLSICGLLIYKFGTDA
                     DLPMLYVWAFGVLTAASVVLSYVIPARTNRKYGGTRWGSIGSVIGTIVGIFIPIPLGFL
                     VGMFAGVFIGEMLHDSKDMNKALQSTKGALIGFIYGTGFSFVVGVAMFLVVLLNMFDII
                     "
     gene            14033..14530
                     /locus_tag="PYS58_RS08500"
                     /old_locus_tag="PYS58_08500"
     CDS             14033..14530
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002977585.1"
                     /locus_tag="PYS58_RS08500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08500"
                     /product="hypothetical protein"
                     /protein_id="WP_185247550.1"
                     /transl_table=11
                     /translation="MLHKAIIFSLGIFALTGCDAQKKAKSDSKTPEMTTNTTSDDQKNN
                     LIYLNEGENKFLKEYQMNITFKGVSEDSRCPEGVNCIWAGVALAQVEVMGTSTRPVLLN
                     LASMDFPNRNYHQSADFNGYIITLQEVTPYPKSEGATALNGKYKIGVSIKKAGASSDAT
                     RK"
     gene            complement(14517..15158)
                     /locus_tag="PYS58_RS08505"
                     /old_locus_tag="PYS58_08505"
     CDS             complement(14517..15158)
                     /EC_number="3.2.2.27"
                     /GO_function="GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014937235.1"
                     /locus_tag="PYS58_RS08505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08505"
                     /product="uracil-DNA glycosylase"
                     /protein_id="WP_276285127.1"
                     /transl_table=11
                     /translation="MTWTEILAPIKSTEYFTTLWAKVKNEYATTKVFPPKNQIFRALEL
                     TPFEEVEVVIIGQDPYHNDYQANGLCFSVSEQVTAPPSLKNIFIELKDDLGVVRTSKEL
                     DDWGKQGVLLLNATLTVRAHSPNSHKDLGWETFTNYIIKEISDKKENVVFVLWGAFAQK
                     KAEFIDPAKHFILKSAHPSPFSVYKGFFGSKPFSKINEYLVSKGKKPISW"
     gene            complement(15281..15796)
                     /locus_tag="PYS58_RS08510"
                     /old_locus_tag="PYS58_08510"
     CDS             complement(15281..15796)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002977583.1"
                     /locus_tag="PYS58_RS08510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08510"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_185247548.1"
                     /transl_table=11
                     /translation="MKLKTERLILQEINETHAEDILLIRSNKMNNQFVKRNSPKNNYDA
                     LEFILHIKRETQEKKVVFLGISYQDHRNLIGTICLWNFSEDRKTAEVGYELLPDYHRKG
                     IMSEALTAVLDYGFKNLQLQKIIAITSQYNENSKGLLLKHHFILEKDTKDEHDPDNIIF
                     SLKKTNCS"
     gene            complement(15793..16473)
                     /locus_tag="PYS58_RS08515"
                     /old_locus_tag="PYS58_08515"
     CDS             complement(15793..16473)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PYS58_RS08515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PYS58_08515"
                     /product="hypothetical protein"
                     /protein_id="WP_276285128.1"
                     /transl_table=11
                     /translation="MKLLFFILLLAVINLNAQKKIIIPVINDDKEKYDTDFFSKEIRKN
                     VKDSIYITERENQFYVNDKNGKSLISYTRSYKTDGFSGYDYSQNSLFGVYRLFYPNNIL
                     KEKGIMCWFGFKIGKWYHYDEHGKLVSVENYDKGFDFTYLMIFNYCKKNKIPLEKIEWG
                     LRTSIFKKVKENTFVWVISYFGISDFDKGKKVEKVVQLDGKTGKVIEKSEYPLPVDGET
                     LIKK"
     gene            16536..18683
                     /locus_tag="PYS58_RS08520"
                     /old_locus_tag="PYS58_08520"
     CDS             16536..18683
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007844909.1"
                     /locus_tag="PYS58_RS08520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08520"
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="WP_185247546.1"
                     /transl_table=11
                     /translation="MYIDKEDLDELEFPQLLAEISPFAYSPKTREKILQLRPMEIDEAE
                     LSLKKTSEYLSSFESSNAIPFDEYEDIESELKLMLIENYRLENSAFIKIKTITEQIGRL
                     QKFFPTMPETFPTLLEEVSVLEFRKEIIDKVDKVFNRFGEVKSEASPALKGIRTEIQHA
                     KKAIQENFNRALTTYGQSDFLDDIRETIIDDQRVLAVKSGFKKRVPGRTLGISKTGSIT
                     YIQPDSVVKHYFKLRENEEEEKKEIDKVLRTLTAELSEFQPQLWRYQVYIFDLDLVRAK
                     AKFAELINGVLPKINRHKTLRLKDAFHPLLWLRNKVENKTIHPQTLTLTDHNRIICISG
                     PNAGGKSITLKTVGLLQLMIQSGILVPVHPKSEMFFFEKIMTDIGDNQSIENHLSTYSS
                     RLKKMSGIIREADANTLLLIDEFGTGSDPELGGALAESFMEFFYDKKSFAIITTHYTNI
                     KLVIEQLPNAQNAAMLFNEETLEPMYKLEVGQAGSSFTFEVAEKNKIPRFIIHSAKKKV
                     EHDIVNLDKTIVKLQQEKYEVEKLKTDLAERKESVEDKRDNLQKLNDQLQQKLFNFQKL
                     YEEEHRKLQFGNKIEAFIDSYTKGKSRKDVVKDFVKLLEQEKFRKIGADKDESKRLQVV
                     KRKITQQLKKEDVIEKIAETNEKLEEKRKSDRAVWMKEGQRVRITGSTSVGTIEKISRN
                     KVIVNYGTFKTTIDADELERI"
     gene            18821..19483
                     /locus_tag="PYS58_RS08525"
                     /old_locus_tag="PYS58_08525"
     CDS             18821..19483
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016198498.1"
                     /locus_tag="PYS58_RS08525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PYS58_08525"
                     /product="hypothetical protein"
                     /protein_id="WP_185247545.1"
                     /transl_table=11
                     /translation="MKPLKVLSDLIPIPSYTVIILCFFFPFFLIKCGDTTLMSIKGTDL
                     VTGVSKQAMNERMKENLKKSSPFGSAFGNDSDNQSSNSDSEYSPLNDSNNKNDKENIPP
                     SPLIIIAFLAAIAGIIIHAIKSIKKKYIWHITISLIGLISLLTFYLTFQSKMEGLGNNK
                     VGMGLGGGVTISYGFGTAFYVCGALFLLVLFFFGVFSYYLKNDPKAIYDSSNQRSES"
     misc_feature    complement(19921..19934)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 22.87"
                     /tool="antismash"
ORIGIN
        1 agctaccatt tccgttacag gaaaagtgtt ggtttctcct ttttcatttc ttgcaacgat
       61 tacagaaagt tctttatcaa tatctaccag gctttcaatc actgaaggct ctttccatag
      121 atgctgataa tcgtcttctg ttttaataac ctgtaccccc tttccgtcat acccacctgt
      181 attcattttc tgcacaaatg gcaatggcat catgatcttt tcatcacggc tccataccac
      241 ctgaaattcc gggcttggga tatcgtgagt tttataaaat tccttctgaa ggattttttg
      301 ctggatagtt ttgatgatac cggcattagg aaccactcgg attccctgtc tttcaagttc
      361 ggccagtgca tcagcattta cgtgttctat ttcaatggtc accacatctt tgtcttttcc
      421 aaaattcaga acggtttcat aatcattgaa atttccctgt gtaaaatacg agatattatg
      481 gcatggtgca tcagaagcag gatccagagt ataaaactca tcatcatact tcaatgcatt
      541 ttgtatcaac attcttccca gctgtccgcc tcccagaatt cctattttca ttttttattt
      601 ttattagatt tacgcttatt gaattttatc aatttttaaa tatcctaatc ccatcgggtt
      661 ctcctgattt tcaatatcag attttgtgag aacaatagaa tatttttctt tcatagcttc
      721 cggaagaata tcattgacat taaaaatgtc atcaatatct actccatgct tgtcatcaat
      781 atggcttact gctccttcaa atcccatggt cttataaaat tcggtagctt ttgctctttt
      841 cacaatttct cccatcgatt tccctaccat cagatgctgc tcatggaatt cttcaaaaaa
      901 acctggctta tatcctccta aattaaggaa gaacagctga ttttctgatg tattttcgct
      961 tttatcaacg atgttcactt cgtagccatc agcaaatctt acttcctgat aacagtcaag
     1021 gtgaatcttt ccttccgcct ccttccaaaa ggctttcata tctggaatca aatctttcag
     1081 actttcagca attccaaaaa acacgtcatg ttgctcgatg tttcttcctt tgggagttgc
     1141 cccaaggatt acataaaata atttcatttc acttttcatg catacaaaaa tacgttaaat
     1201 ttatcttttt caaatgtttg gcagactact acaataattt tatatttgta acattaattg
     1261 tagtatgtca gaaatcatca tactcttctt tggcgctatt tctgcgggcc tattaggttc
     1321 acttacaggg cttggaggag gggttattat tatacctttg ttaacgctgg gattcggcgt
     1381 tccaatgcat tatgccatcg gtgcttctct tatttccgtg atcggtacct cttccggtgc
     1441 cgcggtagct ttcgtaaaag aaggttttac caatatgaga atcggaatgt ttctggaaat
     1501 tgccactacg gctggagcta ttgtaggcgc tttagtttca ggaatgctta atccgaatac
     1561 cattggaatt attttcgcaa gtattcttct tcttacggtt gccttaaact taaaaggaaa
     1621 acctgatcat caggaacctc tgatccatgg aagccttgaa gaaaaattaa aactttacgg
     1681 aacttttccg gataaaggaa tattaaaaag ctactcagca agaaatacag ttcctggatt
     1741 tttaatgatg atgtttgccg gggcaatgtc cggactgcta ggtattggat ccggagcatt
     1801 aaaggtattg gctatggaca atatgatgaa actgccattc aaagtttcta ccaccaccag
     1861 taattttatg attggagtaa cggctgttgc cagtgcgctg atctacttcc agagagggga
     1921 aattattcct gtaattgcag ctcctgtact gattggagta gtgattggaa gttttatagg
     1981 ttctaaaacc ctaatggttt ccaaaacgaa aaagttaaaa gtatttttcg ccattgtaat
     2041 taccattctt tcggtgtata tgatgtataa cggtatcaac aaaagcttca gataatgaaa
     2101 aagaatttta cagatgtaga tctgaaccgc tccgtaggaa atcttctgag actgggtgtc
     2161 attctgtctg tggctacttc actgattggc ttcatcaagc tgtttaccga aggttttgaa
     2221 atgcctaaaa aatacaccag ccttgttgta ggaacttctt ctgaaaaagt ttggggccac
     2281 ttttggaact ctttatgcaa aggggaagga atggctatta ttcaactggg aattctttta
     2341 ctgattttca ctccactcat gagaattatc tttgctttaa taggctattt aaaagaaaaa
     2401 gattacatat atgttttcat ttcttcagtt gttttagcaa ttatggcagt aagctttttt
     2461 gccgggtacg cacattaatt acatttcata aaactccaac ggtaactgat ccggatcctg
     2521 ggtaaagaaa aattctttcc ctgtgaactc atctatgcgg atttcttcac acatgagccc
     2581 tttctctgtc agctcgtttc gtttttctgc cacattttct acggaaaaag caagatgcct
     2641 taaaccacag gcttcaggac gggatggacg ggcaggcggg ttcggaaaag aaaacagttc
     2701 aatcacataa tgttccccaa tagcaagatc tagcttataa gactgccttt cctcacgata
     2761 tacctcacga acaatttgca agcctaaagt ctctgtgtaa aatctctttg atacttcgta
     2821 atctgagcca atgatggcta tatggtgaat tttcattttt taaaattttt gaaatttttc
     2881 tattaataac ttcttttata ttttctgaag ttttctttct actttgtctt ctctcaaata
     2941 tcgctctatt tttatagaat gtatatgaat atgagcaccc tttccttcat taatcttaaa
     3001 cattttgaat tgtatgtctt caatcatctg atcatcaaac tgaatcctat ctatctactt
     3061 aatttcttta cagttttcct ttcttcgggt atcaataata tattgaatct tccattcatt
     3121 attctgctta actaattgaa aactattggc accacaatgg gttaattttc ctttcagata
     3181 aaaggtataa ggtgtaaaca cactggccag gcttccgtct acatgaacag cttctatcat
     3241 aattctttcc tccagatcat cctttgtaag cttagaaaca actgccatga attgcggtac
     3301 attatcggtt tttataatac cctcgtttgt aatggtctgc ataatcgcat gttcagcaaa
     3361 ggctgctttt acaagcccag gatcagcatt tttcataccc aggaacagat tatgaatagg
     3421 tttttctatt tcctgattct gctgcccgaa acagaagcca ctgaatacga ggagaattgc
     3481 tgctattttg ttcataaggt tgatttatag gataaaaata aggaaaaaaa ggaccgtatc
     3541 tattctcatc ctaaatgtat ataggttctt taagccatta tcctagttgt ttagcttcct
     3601 ataaaatgac aaaataggta aatatttcat ttcacaacaa taataattat tttcaaacta
     3661 aaaaggtgga ctaaagtcca cctctattga atattgtttt atttttttaa aacctcatca
     3721 catctttcac cactccattc ttctgggtat gctgtaataa ttctgcttct atgaatgtta
     3781 tgatttgtcc ttctgaaatt ccacttggaa ataaaaggtg tacattggcc cctgcatcca
     3841 aggtaaagaa taatggaagc ccggtctctc ttctaaaatc ccagatttta ttgatcactt
     3901 ctaacgttcc gctcttcatc aggataaaag ccggatcact catcatcatc atggcgtgaa
     3961 gagtaagtgc ttcatgttct accaatttga taaaacgttc catatctccg cttttcagaa
     4021 tctccttcat cggaacgaaa ttttcccttg cttcctggaa tcttctttct gcatacggat
     4081 tggtcttcat taagccatgt ccaacggttg aagaaacgct tttctgccct tcatgaatca
     4141 acagaaccca gtcattgaag tttttgaata cttcatgaat ttcagtttca ggataaggta
     4201 ctgcaaatag atcagagctt ccttctactt cttctgtttc tccccatacg attaacccat
     4261 tgtataagct tctgcatgcg cttccgctcc ctaatctggc taaaaatgaa gcttttctta
     4321 aggattcttc ttcagagatt ttccctgtaa atgtttcatc caacgccatc aggcatttag
     4381 caatagctcc aaatcctgaa gctgaactcg caattcctga actgtgaggg aatgtattct
     4441 ctgttctgat gatatatttt ccctttaaga tccaaggaag atattgttca atatttctga
     4501 agtatttttc aattttttca gcaaacttca cttcttcatt tcctgccaga aaagtctgta
     4561 cagaaaatga ctcatcagcc aaaaattcca ttacagtatt ggttttacaa tggtttaaag
     4621 tgtaactgat acttgggttg gccggaatct gatgatcata tttcccccaa tatttgatta
     4681 aagcaatatt agacgggcaa ctctctgaaa ccgtttgcgt atgaatagcg aaattgtttt
     4741 ttcctataaa ttgtgtcgtc atagtttaat ttaaagtgat ttacaagacg attaatacat
     4801 cttctctata atatctgcat attttttaag gaccacattt ctttttactt tcaatgttgg
     4861 agtgatttct cctgtattga tgtcaaattc tgccggcatt aatgtaaatt tctttacttt
     4921 ttcataatcg gcaaggtggc tttgcagttc tttaattttc tctttataaa ggttcattac
     4981 cttttcattt tttacaactt cttcccaatt ggtaaaagga atattattct ttttaatata
     5041 atcctgtagg aactcaaaat tcggaacgat taaagcggat acaaactgtc ttccttctgc
     5101 aaccagcata atctgctgaa tgaaattatt attggtcaga aggttttcaa tctgctgtgg
     5161 tgcgatatat ttaccattgg aagttttcat cagatcctta agtctatctg taatgatcag
     5221 attgcctttc tcatctatct tccctgcatc tccggtttta aaccagccat cttcagtaaa
     5281 tactttttga gtttcatcag gtctgttata atatcctttc atgattccgt ttcctctggc
     5341 ctggatctca tctccttctc cgatacggat ttctacaccc ggtaatggtt ttccgctcgt
     5401 agcatgttca aaatgagtta aagggaaaag ggtcaaagta gctgtagttt ccgttaagcc
     5461 atatcctaca gtaacatgga tacctactga ttcaaaaaat ctggttacct caggtgataa
     5521 tgaagctcct ccgcaaggta agaaccatag tcttcccccc attttattct tgatcttgct
     5581 aaagaccaac atatctgcaa tggattcttt tatttttaat cccaaaggga ttgccttttc
     5641 atttcttctt aattctgccg tttcccatcc tgtttttaaa gcccaatcaa agatcttttt
     5701 cttgagggat gatccttctt ctgccttttc cagtactccg gcatatactt tctggaagaa
     5761 cctgggtact gcacacatgg cggtaggttt tacctcttcc aaagctttgg ctacattttt
     5821 cggatcttca agaaaatata ctcttgctcc tccatacaaa cataataaac tccagcttct
     5881 ttcaaaaacg tgacttaaag gtaagaatgc caatgaaagc tcttcttcaa agtttttaaa
     5941 cttaaaaaat tcaaagtgag aatcgaatgc tttaatgaaa tttccatgag taagcataac
     6001 gcctttgggt gttcccgttg ttccggaagt atagatcagc gttgccgtat cttcgtcctc
     6061 ttttttacag atctccagtt ttggagaggc ttttgcgata aaatcctcaa ggtaaaaact
     6121 gctgaactct ttcttgatcc acactgcttt cttagaaaca ataatgattt caagagggtt
     6181 atcttctttg tgcaaaaatt ccaggcaggc atcgtattgc ccttggtttc ctaccagaac
     6241 caccttagct ccggaatctt ttatgatata ttctgcctgc tcagcattat tagtagaata
     6301 aataggaacg gttatcgctc caatggccat tgcagcaaga tccataatca tccattcaga
     6361 tgaattatct gaataaatag ctactttatc tccttcctga actcctgctt cctttaaagc
     6421 attggctgtt ttaaaaataa tttcactgaa tttcttccag cttagctctt tccaagcttc
     6481 ttctttcttt ttaaagccga ttgctgcttt tataggatgt ttttctacat ttttaaggat
     6541 tattgcctct gcaagattca tttcttcagc tttttgtcgt taatataatt gttcaggtga
     6601 aagtcgatgc tctcgtgtat gggaataaac tgataattca gctgttccct gactttttga
     6661 ttggaaatgg tgttgaatga agagatagcc tcaatattgg attctgtagc cattctcagc
     6721 ttgggaatca gccatccgaa aagagtattg gctaatttcc cgatgtttaa ttgagatctt
     6781 gtaagaattc ttgcctcttt aagacctaat ctggttctga cttgttttgc gagatcagca
     6841 tatctgttat tttcggaaac gatgataaaa cgttctccaa aaatattgtt ttccatcagt
     6901 tcgatggcag ttttagcaac atctctcacg tctacatacg ctgatccgcc tgcaaaggta
     6961 aagctgttat cttcaaaagt tgaaaaaagc tcgccactgc tttgcgtcca atttccactt
     7021 cctacaatca ttccgggatt gatgatcact acattcattc cttctgcaga ggctctccag
     7081 gcttccattt cagataaatg cttggaaatc gcgtaggcag aatgctccag tttcggattg
     7141 aagtcagaat cttcatcaag ctctcctttg tcattatagt tatctaaaac ggctacagag
     7201 cttacgtgga gaaatttttt aacatcggat ccttcgcagg catagagtaa gttttcggta
     7261 cctttaatat tggtacggta catttctttt tcatcttgag gatgaaagct cactttcgcg
     7321 gcacaatgat acacctcatc tacccctttt aaggcatctt ttaaagagtc gatatcatca
     7381 aaatccaaat taacccattc gatcttattg aaaaaatcat caggattctc cgtgtaaaag
     7441 ctgtatgaat gccttacttc gtttaaattg ctgcccggtc ttttagaagc acgtacgttt
     7501 ttacctcttt taagaagttc cagcacgatt attcttccca gaattccggt tgcacccgtt
     7561 acaaaaacca ttaattatgt tacttgattg ctgactaaaa tatgacaata ttttctatcc
     7621 tacaattctt caggttcctg taaaaggtcc ccaaaaaact ccttttgcaa atttgcgatt
     7681 tttaaagcaa aattcaactt tatttaacca atattatcat tctggaaatc acaaaagcta
     7741 aaactaaaaa agaggaactg atgattgtag atacaaaagt ttttggatac tttagatttt
     7801 taagtaacca cttacctgta ataagcccat ttaagctttt gtaaaaaccc ttatttccca
     7861 ggaatatcac agttattccc ttcctgcgga agagcgttaa aaaaagtcct gaaagcattc
     7921 aaaaactccc aggactacta tataaaaagt taatcattta taccatgatc atattatctc
     7981 ttcttggagc tttatcacag agaacatctg caatactttt agagataaga ttgccttctg
     8041 taagattatc caaccagaaa aattctccgg cagcattgat ttcgatgaaa taatattcat
     8101 cctcaggaga aacaataata tctatggctc catagtctac attataaata tcaagaagct
     8161 ccagaagctt ttctttaaca tccgccggca gcgctgtctg tttccattta tccaaaagat
     8221 taaccccgtc ttttctccag tcaactttag catcttcgta ctgttgagaa tccacttcaa
     8281 aagcataaac atctcttcct acaatggtga cacgaagttc ttttttcttc tgaatcattt
     8341 tctggaactg cattgggcaa tacagcagtg aatccaattc ttcaagttta tcttcactaa
     8401 caatattagt gaagaccacg ttttctattc cgttttcata gatagcaaaa cctgtttgca
     8461 ttttggccac tacattctga tgcttcagaa taaaccgctt tgcctcttca ggattattcg
     8521 tcagacaggt ttccggaatg gtgagtccga ttttctgagc aattttcaat tgctcttcct
     8581 tactatccaa cctcctgtaa acacttggtt ttcccagcgc atacacgtca atagattcaa
     8641 agaacccgaa taatgtattg cggatttccc ccatggctgc tgcaaagaat tttgcatcca
     8701 tctcatcctt caagcctttt ccgatattgt atgctctgcg ataccagact gcagagatat
     8761 catccaaacg gtattttttt tcagatgttt ccagaacggt cacccaagtc ccgtcttgaa
     8821 aaacagttga cagcttattt tgtaaaggat acagatcaac atcaaaacga atgacttcac
     8881 aattattctc tttaatatat tccgttactt tttcaataga aaagttatct gcagtatgtg
     8941 ttataattaa aattttattc atggatattg attcttttaa taaggtgatc ggcaattctt
     9001 tctgcgatag gaaatccaag ttctttttga agcattcccc actctccctg cggattaatc
     9061 tccaggaaat aatatattcc atcttttccc ctgatcatat caatagcacc cgtatacaat
     9121 cccatctctt tcatcatgga agtcagttta attttgacat catcaggcag ttcataagtt
     9181 tcccagaaat agccttcatg gcttactctc caatctgcat tttcactgtt attgatcttt
     9241 cctgtaaaaa acgctccatc tacatacata atccttaatt cgtatttctt atcaatataa
     9301 ggctggaaaa tcatgggaca atagataata tctgaaaggt tatcaagtgt ttcctgctca
     9361 atgatcattg tagagatcag attttggcca ctcattgttt tccgggccac gccatgaagt
     9421 ttggcaatgg cttttcctga acactgctgg tcaaaaaaag cttttacttt ctcctcatca
     9481 ttggaaaaaa tggtaggtgg aatgataagt ttattttgct gggctatttt tagctgaagc
     9541 attttattcc catctatttt cttttcattc tcgtaaggat taatccatgg aagatgttcc
     9601 agttgggtaa acagattgta gcggaggctt gcatattcat tccgaaagat ttgttcatat
     9661 tcttcatcca gttcttcagg aacattgata ggccatgctt ttctatgcca tacacctgta
     9721 atatcattgg aatgaataga gttaccttcc tcatcagtaa tctcaaatga gtactcactg
     9781 atgctgatct tccggagatg attcaactga tcagaattaa gtctgaagta aggaatattt
     9841 ttagaagaaa ggtgttgaaa gaaacgatca atagtataaa aatcctgtga gtgggtaata
     9901 cagagaatca ttttgccgct ttattaaaaa gggaaactta acatgttaag tttccccctt
     9961 tgttacaatt ttgttaatat gttactgtaa aataatcatt ttatagttga gctgcatcat
    10021 catcaccatc agaaggatat ttcatcgtat gttccatatc attcaactta gaagttgcat
    10081 catcgataat cggttttgta ataacatccc tttccggaat tgtaataata ctcgttcctc
    10141 cttttactgt ttcaggatcc ttaagttgtt tttcaagaaa tgatgcgaaa aacggcttct
    10201 tttttgattt tttgttttcc ataagttaat atgtttgttt atttgataac cgaatgtaca
    10261 aaaatttcaa ctcatggaga aataaataaa cattttaaga taattttaac acattatcaa
    10321 agtataaagt atattattaa ctcaaaccaa gaaactgctt aacaacaaca gcaaaatcag
    10381 cagggttttc ggcctgaacc caatgtcctg catttttaat agttacaatc tttgcttttg
    10441 gaaactgctg cttgattcca tattcatcct gtggtaaaat atagttcgac ttttctcccg
    10501 caataaataa agtgtcaccc tcaaaaactc cgaactttat agcattggat acgaattcat
    10561 tatacttttc agacagagtc ttaaggttaa atctccagtt cagcttttta tcatcatccc
    10621 agtacaggtt ctttgttaaa aactgtattg tagatttttc aggaatatac tggttcaaaa
    10681 cagcttctac ctcatttctt gaacctaccg tattaaaatc tacggtttca agagctttga
    10741 tgattccctg gtggtgtggt ggatacgctt tgggtgaaat atctaccaca atcagtttct
    10801 ctactttttc gggatacttt acagcaaact gcatcactgc ttttcctccc aaagaatgcc
    10861 ctaaaacatg agctttctga ataccgtagt gatccatata acggacaatg tcatccgcaa
    10921 gatcatcatg tgacatatca tcagaatgaa aacttcttcc gtggtttctg agatcaataa
    10981 gatgtaccgg aagatattct ccaaggtctt tcccgaagct tccccagtta tcaagcattc
    11041 caaaaagccc gtggaatact aaaagtggcg tagcggccga accttcgcca aatatttttg
    11101 aatttaagat ttccatattt tttaattaac agatttcaga tacatattcc agataatttc
    11161 agaggtcctt cagattaagg tcttacaatc cgatatctgg accttatatc attatgacca
    11221 ttttgccaat ctctttaaat aagactgaac tgtattttcc aagcccatat ataatgcttc
    11281 agaaaccaaa gcatgtccaa tagacacttc taataaatta ggaatagtat ctgcgaaata
    11341 tttcaggttt tcaaggctca gatcatgtcc cgcgttaatt cccagaccaa attcatgagc
    11401 tacaacagca gtatcatagt aaggtttaat tgccttttcc ttatcagata aatagttttt
    11461 tgcgtaagct tccgtgtaca gttcaattct gtctgctccc gtctttgctg catattctac
    11521 caactcaggc agaggatcaa gaaaaataga ggtacggatg cctgcattct taaattctgc
    11581 aatgatttct gtaaggtaat ccagatgttt tttagtatcc caacctgcat tggaggtaat
    11641 ggcatcatct gcatcaggaa ccagcgttac ctgctcaggt ttcacgtcta ataccatatc
    11701 aataaaagac tgatgtgggt ttccttcaat gttaaactca gtcgtcacca atggcttcag
    11761 atcatagaca tcttttcttg taatgtgtct ttcatccggt cttggatgaa tcgtaattcc
    11821 ctgccctccg aattcctgaa tttttatagc agcctctgtc acacttggtg tttcacctcc
    11881 tcttgcattt cttaatgtcg caatcttatt gatgtttacg cttagttttg tcatttttat
    11941 atttagatat tagataacag aagttagaag atggaagaca gatgctggag gttttatcca
    12001 gatatatgac ttctttaaga tgttctaatt tcattatcat ttaaaattgt ttttttaaac
    12061 aagtattacc ttttcctgtt tatactttaa tacttatctg catcacctga agttcaaatt
    12121 ctttggaagc taccaataaa tgatcaaaaa tatctgcctg aatctgctcg aaatgttccc
    12181 atttagaatc attcgcaaaa caatacactt caagcggaag gccttgtggg gtaatttcca
    12241 gctgtctgac cattcttgtt gcattttttt caatatcggg atcattttcg atatattttt
    12301 gtgcataata tctgaaaacc ccaatattcg taagctgtct tccgttaatg gtcttgtcat
    12361 tattgctcag actttctttt tctctcctga tttccactct tttttgttca agatagtctg
    12421 caataaggtt aatttctttt aaacgctcaa tatcctcatc cgtgagaaat ttaaaagaat
    12481 tgatattaaa atagatagac ttcttaattc tcctgttatt ggattcagac ataatctgca
    12541 tatttttgat ctctgtagtc aggaaatcat aggttggaat ggtagaaacc gttttatcaa
    12601 aattggtgat ttttgtagtc agaaggctta tctctgtaat atttccttct atactgtatt
    12661 tgggaatact gatccaatct ccaactttca tatttttgga agtcgccacg tgaatccctg
    12721 ttacaaatcc aaggatggta tctctgaaaa caagcaccaa aactgctgta atagccccca
    12781 aacttccaac aatagtagtt cctttaattc cgaagaccac acaaagcccc actacagaaa
    12841 acacaaaaat ccccaggatt ttcactgttt ccgaaatggc attcaatgcc ataattttat
    12901 agaaatcctg tttgatagaa aagtaatttc tcaatgccgt taatgacctg tacaacattc
    12961 cggcaagaat catgaccagt cccagattca cacatcgtat gataaaaatg gtagttttag
    13021 gtaacgctcc ttccggaaat atggacccct gtatccctcc aacaatcgta agagcggcaa
    13081 aatgtgctac cgaattggtg atcttggatt gataaataga tttaagtaca gggaatttat
    13141 tttcattatg aaaaagacga aaaacagcat tgatagaaaa ttttaaaaca aaatctacaa
    13201 tcaggaatac tgcgcagagc aatgccagct ttacaatgat atgaaaaacc caatccaacc
    13261 ctgagggtga aatctgggtg atataaatgt ataactgttc gcttatttcc tgcaaatagt
    13321 ttttggtatc ctgtaggtca tctttcatta cagcaaattt ataaaattaa ggatgatcat
    13381 gttactattc acaatcaatt ttcatcccaa attttaaaag gactataaaa ttctctctaa
    13441 tcattcagta cactcaggga ttttcatcat caggtctatt gttgaatcat taaggtttca
    13501 tatcttcgtt tatattttaa agaatggata ccactgtcat taatattctc tgtcttattt
    13561 tattgtttgt tggaatattg ggaacatttc tcccggtttt acctggactt ttattaagta
    13621 tttgcggttt gctgatctac aaattcggga cggatgctga tctgcccatg ctgtatgtat
    13681 gggcctttgg agttctcact gcggcttctg ttgttttaag ctatgtgatt cctgcaagaa
    13741 ccaacaggaa atatggaggt acccgctggg gaagcatcgg atctgtaata ggaacgattg
    13801 tggggatatt tattcctatt ccgctgggtt tcctggtggg aatgtttgca ggtgtattta
    13861 ttggtgaaat gcttcacgac agcaaggata tgaataaagc tttacaatct accaaaggag
    13921 ctttaatcgg ttttatttat ggtaccggat tcagtttcgt agtaggtgtg gcaatgtttt
    13981 tggtagtact tcttaatatg tttgatataa tttaactaaa aaagaaaaaa ttatgctcca
    14041 taaagccatt atattcagcc tgggaatttt tgcattaacg ggatgtgatg cccaaaagaa
    14101 agccaaatca gattcaaaaa cccctgaaat gacgaccaat acaacgtctg atgatcaaaa
    14161 aaacaatctc atttatctga atgaaggtga aaataaattc ctgaaagaat atcagatgaa
    14221 tatcacgttc aaaggggttt ctgaagacag ccggtgtcct gaaggggtaa actgcatctg
    14281 ggccggagtt gctcttgctc aagttgaagt gatgggaacc tctacccgac ctgtactttt
    14341 gaatcttgcc agcatggatt tccccaatcg aaactatcac caatcggcag atttcaatgg
    14401 ctatatcatt acattacagg aagtaactcc ctatcctaaa tcagaaggag ccacagcatt
    14461 aaatggaaaa tataaaatag gagtaagtat caaaaaagcc ggagcttcat cagatgctac
    14521 caggaaatag gtttctttcc tttggagaca agatattcgt tgatttttga gaaaggctta
    14581 cttccgaaga aacccttgta aacagaaaat ggtgacgggt gtgccgattt caatataaaa
    14641 tgcttagccg gatcgatgaa ttcggctttt ttttgtgcaa aagcgcccca caatacaaaa
    14701 actacatttt cttttttatc tgaaatttcc ttgataatat aattggtaaa tgtttcccag
    14761 ccaagatctt tatgtgaatt tggtgaatgg gcacgaactg ttagggttgc attcagcaaa
    14821 agaacacctt gctttcccca atcatccagt tctttggaag ttcttacgac cccaagatca
    14881 tcttttaatt cgataaatat attcttaagg gatggtggtg ctgtaacctg ctcagacaca
    14941 gaaaaacaca aaccatttgc ctgataatca ttatgataag gatcctgacc gataatcaca
    15001 acttctacct cttcaaatgg cgtcaactct aatgctctga agatttgatt tttaggagga
    15061 aaaaccttag tggttgcata ttcatttttt actttcgccc aaagggttgt aaagtattcc
    15121 gtacttttta taggggctaa aatttctgtc caggtcatac tgcaaaagta attaatatta
    15181 aaataaaagt atagctcaat cattaaatat cttcactttt cttttgatta gcctataaga
    15241 aaaatagtac aacacgatag aaaaagggat gcatgtaaat ttatgaacaa ttagtttttt
    15301 ttaagctaaa aataatatta tcaggatcat gttcgtcttt tgtatctttt tcaaggataa
    15361 aatgatgttt taaaagaagt cctttagaat tttcattata ctgactggta attgctatta
    15421 ttttctgcaa ctgcaggttt ttgaagccat aatctaaaac agcggtgaga gcttcagaca
    15481 taattccttt tcgatgataa tccggaagca gttcataccc cacttctgcg gtcttcctgt
    15541 cttctgaaaa gttccataag caaattgttc caataagatt ccggtgatct tgatatgaaa
    15601 ttcctaaaaa aacaactttc ttctcctgag tttctctttt gatgtgtaag ataaattcca
    15661 acgcatcata attgttctta ggagagtttc tttttacaaa ttgattgttc attttattac
    15721 ttctgatcaa caaaatgtct tcagcatgag tttcattgat ctcctgcagg atcagtcgtt
    15781 ccgttttcag tttcatttct ttattaaggt ttctccatct acaggtaaag ggtattcact
    15841 tttttctatg acttttccgg ttttgccatc caattgaacg actttttcaa cttttttgcc
    15901 cttatcaaaa tcacttatcc cgaaatagct tattacccat acaaaagtat tttcttttac
    15961 ctttttaaaa atgctggttc taagtcccca ttctattttt tctaagggaa ttttattctt
    16021 tttacaataa ttaaaaatca taagataagt aaaatcaaac cctttatcat agttttctac
    16081 agaaacaagt tttccatgct catcataatg ataccatttc cctattttaa atccgaacca
    16141 acacattatt cctttctctt ttaatatgtt attgggataa aacaacctat aaaccccaaa
    16201 caaggaattc tgtgaataat catatcctga aaaaccatcc gttttatatg atcttgtata
    16261 actgatcaat gattttccat ttttatcatt gacgtaaaat tgattttccc tttccgtgat
    16321 atagatgcta tcctttacat tttttcttat ttctttagaa aaaaaatctg tgtcatattt
    16381 ttctttatca tcattaatta ctggaattat tatcttcttc tgagcattca gattaatgac
    16441 tgccaaaagc agaataaaaa ataataattt catagatata ttttgtaaat cattcaaata
    16501 tacgtaataa tcaaaattct cactaaattt gcactgtgta tatagataaa gaagatttag
    16561 acgaattaga gtttccgcaa ttgctcgcgg aaatctcccc atttgcgtat tctccgaaaa
    16621 caagagaaaa aattcttcaa cttcgtccga tggaaattga cgaggcggag ctttcattga
    16681 aaaaaacgtc agaatatctg tcgagttttg aaagctcaaa tgcgattccg tttgatgagt
    16741 atgaagatat tgaaagtgag ctgaaactga tgctgattga aaactaccgt ctggaaaaca
    16801 gtgctttcat caaaataaaa accatcacgg aacagatcgg aagattacag aagttcttcc
    16861 ctaccatgcc ggaaacgttt cctactttat tggaagaggt ttcagtactg gagttcagaa
    16921 aagagattat cgataaagta gataaggtat tcaaccgatt tggtgaggtt aaaagtgagg
    16981 cttctccagc tttaaaaggg ataagaaccg aaatccagca cgctaaaaaa gcgattcagg
    17041 aaaacttcaa tcgtgctttg accacgtatg gacagagtga ctttttggat gatatacggg
    17101 aaacaattat tgatgaccaa agggtattgg cggtaaaatc aggatttaag aaaagagttc
    17161 cgggaagaac cctgggaatt tcaaaaacag ggtccatcac ctacatccag ccggacagtg
    17221 ttgtaaaaca ttacttcaag cttcgtgaaa acgaggagga agagaaaaaa gagattgata
    17281 aagttttaag aacccttact gcagaactgt cagagtttca acctcaactc tggagatatc
    17341 aggtgtatat ttttgatctt gacctcgtaa gagctaaagc taagtttgca gaactgatca
    17401 atggtgtact tcccaagatc aaccgtcata agactttgag actgaaggac gcttttcatc
    17461 cattattatg gctgagaaat aaagtggaaa acaaaacgat tcacccacaa accctgactt
    17521 taaccgatca caacagaatc atctgtattt ccggacctaa tgctggtgga aaatcaatta
    17581 cattaaaaac agtaggattg ctgcaactga tgattcagag tggaattctg gttcctgttc
    17641 atccaaagtc tgaaatgttt ttctttgaaa agatcatgac tgatattggt gataatcaat
    17701 ctattgaaaa ccatctttcc acctattcat caaggttaaa gaaaatgtcc ggaattatcc
    17761 gtgaggctga tgccaataca cttttactga ttgatgaatt tggaacaggt tctgatcctg
    17821 aactgggagg tgctttggct gaaagtttca tggaattctt ctatgacaag aagagttttg
    17881 cgatcattac cacccattac accaatatca aattggtaat agaacagctt ccgaatgctc
    17941 agaatgcggc gatgcttttc aatgaagaaa cactcgaacc catgtacaaa ctggaagttg
    18001 ggcaggcagg aagttcattt acttttgaag tggctgaaaa gaataaaatt ccaaggttta
    18061 tcattcattc tgccaagaaa aaggtggaac atgatattgt gaatctcgat aaaacgattg
    18121 taaaactgca gcaggagaaa tatgaagttg aaaaactaaa aactgatctg gccgaaagaa
    18181 aagaatctgt agaagacaaa cgtgataatc ttcagaaact gaatgaccag cttcagcaga
    18241 aactgttcaa ttttcagaaa ctttatgaag aggagcatcg caaacttcaa tttggaaaca
    18301 agattgaggc tttcattgat agctatacga aaggaaagtc cagaaaagat gtggtaaaag
    18361 attttgtgaa gttgcttgaa caggaaaagt tcagaaagat tggtgcagat aaagatgaat
    18421 ccaaacgtct tcaggtggta aagagaaaga tcacgcaaca gcttaaaaag gaagatgtga
    18481 ttgaaaaaat tgctgaaacc aatgaaaaac tggaagagaa acgtaagagt gaccgcgctg
    18541 tctggatgaa ggaaggccaa cgtgtccgaa ttaccggaag caccagtgta ggaacgattg
    18601 aaaaaatctc cagaaataag gtgattgtta attacgggac tttcaaaaca acgattgatg
    18661 cggatgaatt agagagaatc taattaattt gaaaatggat taatttgcga atttgaaaat
    18721 taactgaata caataatgga agagagtgtc ttaagatgct ctcttttctt ttgttcatta
    18781 tcatcataat ttttcctatt tttaacagaa acaataattt atgaaaccat taaaagtact
    18841 ttcagacctt attccaatac cgagttatac ggtcattatt ctgtgttttt tcttcccatt
    18901 ttttctgata aaatgtggag ataccactct aatgtctatt aaaggaacag atctcgttac
    18961 aggtgtttcc aaacaggcca tgaatgagcg tatgaaggaa aatctgaaga agagttctcc
    19021 atttggatct gctttcggaa atgactcaga caatcagtct tccaattctg attcagaata
    19081 ttcaccactg aatgactcca ataataaaaa tgacaaagag aatattcctc caagtccgct
    19141 tattatcatt gcttttcttg cagctattgc aggaattatt attcatgcga taaaaagtat
    19201 taagaaaaaa tatatatggc atattactat ttctctgata ggccttattt ctttgttaac
    19261 tttttatctt acttttcaat ccaagatgga aggccttgga aataataaag ttggaatggg
    19321 attaggaggc ggagtgacca ttagttacgg ctttggaact gctttttatg tatgtggagc
    19381 attatttctg cttgtactat tttttttcgg agtattttct tattacctta aaaatgatcc
    19441 taaagctatt tatgactcgt ctaatcagag gtcagaatct tagtacaaac aaaaatattt
    19501 aaaaaccaaa gcctatgaca aactaaacct tagcaaagaa tccctggaat ggctacagga
    19561 gaatgacaag tattatattc ctgatgatga attttataaa ttattcagag gatattgata
    19621 atttcaataa atacattttt attttcctca tccaaaaagc atttaattta tatatttggg
    19681 aatctaaaat ttgttaagat gatttcagta aacaaagcat tgtacctatc tgcattcagt
    19741 attttttctt tagccttcgt taaaggtcag aacaaagttc cttttggtgt ggtaaaagct
    19801 gaagaaggat acgccaatgt gcgtgtacat aaggataatt acagaaaaat agtagataaa
    19861 atccgtatgc gtaaaggaga tgtatttgtt tatgtgaaac ctgctccggg agaaacggaa
    19921 tggatctgga tcaaatatcc cgaaaaacag gacgaggaaa aaccttttgt acgctatgaa
    19981 actcttgata aagaaggaat ggtgaataaa gagcgtattg cctttatcga tcagcttcct
    20041 gcttatacac cttctaagtc taaaaacgga aaatccctga tctttaccga taattctgat
    20101 cccaaagttc ccactgctca aagaagtaag gttgttattg acatctatcc atccaatgcc
    20161 ggttaccgta aaaaggaaaa agatgctgaa ggaaagcttc ttaccattga taaagtaaaa
    20221 cc
//
