LOCUS       NZ_CP119144            20684 bp    DNA     linear   CON 22-NOV-2023
DEFINITION  Streptomyces noursei strain C27 chromosome, complete genome.
ACCESSION   NZ_CP119144
VERSION     NZ_CP119144.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces noursei
  ORGANISM  Streptomyces noursei
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9627936)
  AUTHORS   Go,B. and Lu,Y.
  TITLE     Control effect and mechanism of Streptomyces NK27 against gray mold
            of grape
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9627936)
  AUTHORS   Go,B. and Lu,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2023) State Key Laboratory for Biology of Plant
            Diseases and Insect Pests, Institute of Plant Protection, Chinese
            Academy of Agricultural Sciences, Yuanmingyuan, Beijing 100193,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-OCT-2021
            Assembly Method                   :: ABySS v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 98x
            Sequencing Technology             :: Complete Genomics
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/22/2023 14:00:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,442
            CDSs (total)                      :: 8,348
            Genes (coding)                    :: 8,203
            CDSs (with protein)               :: 8,203
            Genes (RNA)                       :: 94
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 145
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 145
            Pseudo Genes (frameshifted)       :: 46 of 145
            Pseudo Genes (incomplete)         :: 121 of 145
            Pseudo Genes (internal stop)      :: 12 of 145
            Pseudo Genes (multiple problems)  :: 30 of 145
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:17:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 97087
            Orig. end                         :: 117771
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP119144.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20684
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="2"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20684
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20684
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10684](+)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10684
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     misc_feature    1113..1127
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.63"
                     /tool="antismash"
     gene            1292..1666
                     /locus_tag="P0D74_RS00425"
     CDS             1292..1666
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971536.1"
                     /locus_tag="P0D74_RS00425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /protein_id="WP_275467440.1"
                     /transl_table=11
                     /translation="MIPKLQAVALDCADPVRLAEFYAELLGGRVVADPEDPGWVEVQGF
                     EGTPLACQRVDGYRPPDWPGQQRPQQLHLDFDVDDLDGEEKRVLALGATVLERTDQIRP
                     GANWRVYADPAGHPFCLCLH"
     gene            complement(1850..2797)
                     /locus_tag="P0D74_RS00430"
     CDS             complement(1850..2797)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016575762.1"
                     /locus_tag="P0D74_RS00430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_275460757.1"
                     /transl_table=11
                     /translation="MTEPSASDRPSVHLPLRTPDLESLRLLVLVADLGSLGRAAERLRI
                     SQPSASRRLSTLERGLGLVLLDRTRRGSRLTLAGQVVTGHARSVLAELDDLLTGAGKLR
                     DRREAELRVAASLTIAEYLLPTWISELRSRRPELYIGLQVTNSEHVPELVEAGEADIGF
                     IEGPRLSRVMSTRQVAEDRLVVVVDPGHPWARRREPLSARELSRTPLVLRESGSGTRQT
                     LDRALHLAGCDRARPLVELGSTAAVRGAVIAGTGPSVLSELAVRGDIVEGRLTGVEAAG
                     VDLTRDLRAVWPTGRRLVGPAAELVAVARREVTV"
     gene            2893..3981
                     /locus_tag="P0D74_RS00435"
     CDS             2893..3981
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014150862.1"
                     /locus_tag="P0D74_RS00435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative sulfate exporter family transporter"
                     /protein_id="WP_275460758.1"
                     /transl_table=11
                     /translation="MKDASLPRPTRPPDLAPARKPGAAFVDRLPGLALAVAVALVATSL
                     GRLVPVVGGPVSGIVLGVLVAVVARPGARMRPGIAFAGRGVLQAAVVVLGAQLSLGQVL
                     RVGVGSLPVMIVTLAVCLAAAYGIGRRLGVVRDLRTLIGVGTGICGASAIAAVTPIIGA
                     AEAEVAYAVSTIFVFNIAAVLTFPVLGHLLGMGQHAFGLFAGTAVNDMSSVVAAATTYG
                     GPAADYAVVVKLARTLLIIPICLGLAALARRRARTTDAGAAGSGEGLPSRVRVGRLVPW
                     FLGGFLVLAAANTAGLVPSAAHGPLSALAVFLITVALSAIGLSTEPAKLRRAGAAPLLL
                     GGCLWLVVSATSLAVQFLTRYL"
     gene            complement(4662..5534)
                     /locus_tag="P0D74_RS00440"
     CDS             complement(4662..5534)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="P0D74_RS00440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_275460759.1"
                     /transl_table=11
                     /translation="MKTSRIFPASHASLRAVCTAAVLAGAMAVPTTAFAVGTPEQQDRP
                     ASAGAARTAPQEPAKDRVRAVGLGGGMEAVIHNGVCDLQAIGSGKPFATLKKGQSYNKG
                     IYVYFDGTHVHSRAQGVNNHDKNKPGPARTVTLTNGARATVQKVNGSYTAKIQLKNKQI
                     ATLSSTHRSVTHEGVRYTVNPANGSVAIQNMKKRQGVHPAKHRVIHAKTQMHRVPQRRF
                     QAPVAPQAQPFVTEQAQPPVTSQAQPPVTGQVQAPAYGDWAAHHSYRPTGRAGAVAMSF
                     AAAGSGGGR"
     misc_feature    5549..5563
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.88"
                     /tool="antismash"
     misc_feature    complement(5557..5572)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.95"
                     /tool="antismash"
     misc_feature    complement(5567..5582)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     misc_feature    complement(5996..6009)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.58"
                     /tool="antismash"
     misc_feature    6046..6061
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.09"
                     /tool="antismash"
     gene            complement(6271..7188)
                     /locus_tag="P0D74_RS00445"
     CDS             complement(6271..7188)
                     /EC_number="3.2.1.96"
                     /GO_function="GO:0033925 - mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016328159.1"
                     /locus_tag="P0D74_RS00445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="endo-beta-N-acetylglucosaminidase H"
                     /protein_id="WP_275460760.1"
                     /transl_table=11
                     /translation="MTFALGRGRARTAAFALLLVAALSAGAKAAASPAAAAPVKKGPTS
                     VAYVEVNNNSMLNVGKYTLAKGGANVFDVAVIFAANINYDTTKKSAYLYFNENVQRVLD
                     DAAHQIRPLQAKGIKVMLSVLGNHEGAGFANFPSKEAASAFAKQLSDAVGKYGLDGIDF
                     DDEYAEYGKNGTGQPNDSSFVHLVSALRDYMPDKLISLYSIGPSAEKLSYGGVDITSKF
                     NYAWNPWYGQWQVPGISLPKSSLSPAAVQIGATPAGTAADFARRTVGEGYGVYLTYDLD
                     GSDRHDYLSSFTKELYGSDAVYTP"
     misc_feature    complement(7174..7176)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7619..8353
                     /locus_tag="P0D74_RS00450"
     CDS             7619..8353
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639823.1"
                     /locus_tag="P0D74_RS00450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="trypsin-like serine protease"
                     /protein_id="WP_275460761.1"
                     /transl_table=11
                     /translation="MMRRVRVLLVSTVVLVAGAVMSSAPASAVIGGSKSTYGPWAVRML
                     VDGKPTCTGTAVAPQWIISASHCFFEQAQPVADKRISFRVGNLDMRKGVTVRPVPGRRV
                     GSADADMMLIKVPPMKVRTAPLATAGVHQGQVVRQYGWGATCTGDENTCQSPVLKQSDL
                     RVVRADDPRCEGHTAPGGSDFCMEKVAGIPAGGDSGGPIMSIGPRGTEILVGVFDGSDR
                     EEIAEAGEVSQQLAWIRSVIQH"
     misc_feature    8842..8856
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.12"
                     /tool="antismash"
     misc_feature    9061..9078
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.55"
                     /tool="antismash"
     gene            9061..9651
                     /locus_tag="P0D74_RS00455"
     CDS             9061..9651
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159: dihydropteridine reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572569.1"
                     /locus_tag="P0D74_RS00455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitroreductase family protein"
                     /protein_id="WP_275460762.1"
                     /sec_met_domain="PF00881 (E-value: 1.2e-12, bitscore: 47.2,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTQSSSESPPEPLADALTVLKTRTAVRNYSKEPVDDALIGRLLE
                     AMLAAPTASNRQAWSFVVVRRPAGVRQLRAFSPGVLGTPAFFVVACVDRSLTDNLSPKL
                     SQTIYDTSKLCVAMAVENLLLAAHAFGLGGCPVGSFRSEIVKSMLGIPEHIEPMLVVPI
                     GRPATALVSSPRRAKNEVVNYESWGNRAAAPTP"
     misc_feature    9064..9066
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            9611..9928
                     /locus_tag="P0D74_RS00460"
     CDS             9611..9928
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_039632579.1"
                     /locus_tag="P0D74_RS00460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6092 family protein"
                     /protein_id="WP_037634412.1"
                     /transl_table=11
                     /translation="MNPGETVLPPQLREDIALLAAFLLSSGRGLLDEPADYGIYRCTDG
                     ARRVLQLLDEHGGSTARLTAVRERLDEVMFAPMGEDRDMGEILDDLCRQMAGALPEIET
                     P"
     gene            10001..10684
                     /locus_tag="P0D74_RS00465"
     CDS             10001..10684
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04539.1"
                     /locus_tag="P0D74_RS00465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_275460763.1"
                     /sec_met_domain="CDPS (E-value: 4.6e-67, bitscore: 224.8,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREEILGNRGRKIRQRGEHALIGISAGNSYFSQKNVTMLLQWAGQ
                     HFERTDVVYVDTHIDDMLMADGRSAQEAERSVKRTLKDLRRRLRRSLESVGDHSERFRV
                     RSLSELQETPEYRAARQSTDRAFREDGEFATVCEEMVRAVVMNRPVDGVGISEEHLRAG
                     LNYVLAEAPLFADSPGVFSVPSSVLCYHIPTPVSTFLAHRETGFQAAQGQAYVVVRPQE
                     LADAA"
     gene            10822..11373
                     /locus_tag="P0D74_RS00470"
     CDS             10822..11373
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020115668.1"
                     /locus_tag="P0D74_RS00470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_275460764.1"
                     /transl_table=11
                     /translation="MVRPLLLVDVDGPLNPYVAKPQRRPAGYQTHRLLTPRWEAAQRRR
                     LAEWGTPDARVKPLRVWLNPEHGPALRSLPFDLVWATTWEDEANAYVAPVLGLPDLPFI
                     AWPSPRPEPEGGVFWKTPAIVAWARGRAFAWVDDDITRADRAWVAEHHDGPALLHRVDP
                     RHGLTVDDFATLTAWASGLG"
     gene            complement(11441..12394)
                     /locus_tag="P0D74_RS00475"
     CDS             complement(11441..12394)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572573.1"
                     /locus_tag="P0D74_RS00475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_233659142.1"
                     /transl_table=11
                     /translation="MDLEAVRTFVAVADAGQFQEAAVELAVTQQAVSKRIAALERNLEV
                     RLFTRTPRGAQLTIDGQAFLPHARELLRVADRAVASVRAGRRPLRVDVINSRGAASGLM
                     RDFHRAHPEIDLDVMLLFEIDTAVAALRSGAIDASFRAVGVPGRPLPPDIESVRVVDEP
                     LQLLTGPAHALAGARSVTMAQLVGHRIWMPGIVPGTEWAAYYDDLVAEFGLTIEATGPN
                     FGSDALLDTVADTPALATFMGAHTRLVWPADHGLRRIPVTDPTPVYPHALLWHRDNPHP
                     ALAALRAHLAGTAADHDATGTWTPDWTPDWTTATAR"
     gene            12529..13797
                     /locus_tag="P0D74_RS00480"
     CDS             12529..13797
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572574.1"
                     /locus_tag="P0D74_RS00480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_275460765.1"
                     /transl_table=11
                     /translation="MGNGHRLGRRFGWLWGAYGASALGTWLAFGAFPLIAIHVLHAGPA
                     QVAALSAVGAAVGAAVAVPLGPWVEFRRKRPVLIGTDLVRFAALLTIPVAFACGVLSFV
                     QLLLVAVVVSAADITFRAASGAYLKTLVPAEDLLVANARFESTTWTTTVVGPPLGGAAI
                     GLLGPVATVVADAVSYLLSALGIRATGGDEPRPERRPAARLRAGDLLDGWRYILADRTL
                     RPLFFNTALFNGLLMAADPLLAVLMLGPLGFSPWQYGLAFAVPSLGGLLGSRLARPLAA
                     RFGQHQVLVAVGTLRALWPVGLAFIGPGTGGLLLVMGVELGLIFCCGVFGPVYATYRLE
                     RTANDRIARTLSAWSVTTKAVTALLTAVWGALAGLLGPRTAIGLAGVLLLATPLLLPRR
                     AAPPHAAPEPAPAPAPAPAPDGA"
     gene            complement(13841..16738)
                     /locus_tag="P0D74_RS00485"
     CDS             complement(13841..16738)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539346.1"
                     /locus_tag="P0D74_RS00485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M48 family metalloprotease"
                     /protein_id="WP_275460766.1"
                     /transl_table=11
                     /translation="MKAFAGLRSATGTGPRFALLMVLVVVSSIPTLDELLQSAPALLGL
                     RDGREALHGPSGCLYAAGFDPGSSDPQNLLTALTRPGTLYQCIGDHTLVPYRGALATVV
                     LLALAAGLYWWLPAARERWRRMLPLEAVDLDGTLRAELAALCARTGIRARLRFRVDPAR
                     TTSGASVHGRSGNYTVCLHSGLLPRLRTDPAGFRAVVLHELAHVHHRDVDYAYASTALW
                     RAYVLLALIPTFAETGWVLALGLSGVKSPWWPGGAAMLLAPALVGLVLAALVHLARADL
                     LRRRELFADRRAVAWGADSASWQHPDPTGPVAPWLRRLTALLGTHPQWAERRRALVDAG
                     RLDRVSALAMFLTGVSAALLYQSLMTLPVLSEGPGSIWITVGAVTPVLCLALGLPLLRG
                     SRRADGHGPSATVAGLWLGLGLLLGQFVASTQYRLDWMLPQPQYLLAFLLIAAVPAVWW
                     SQSLRLALALPRRGHRWAAAACCAAVTAAVLWAGLGWWRVAGESLSLGIGDRGAELAAY
                     YARTVPGDWHGYGPDLLAFSTGLMVLTPLGGDLLAGVATLSLWLVPLALVLLPGVRRTV
                     GGPTGTALRLRRTLGAGLAGALVCGMGLVLAQVAMNQSRPATPKEPAGPFVLVHMWWVT
                     VTVLAACLLTAAVVAAGARRHWLLRALIAAQVVQLLAYAEVFALFSVDGCLGPLNTAFD
                     VCRWRPRNGLTIDGTVTSLTLVNAVLGSACAALVGAGLAWAVRRLRGRPPAHEAAVPVP
                     SPADRPPSTLLKAGTLLALGLPAVVLAAVTFTQAAASDDSRQWQEAADAVRKQRGPAPP
                     AQTPQTRAWQAASWLNAGGTLRAQQINAASIALDSELLKAAAGKRNADGTVALDEQAFH
                     RRCGTLGQRVEEARAYFPVPDRDLQRNWSAALDQLHRGATDCQEATVPPKSAPHRTDAE
                     RERLFTTSLNEVVNAMRTFGTAVLDIKQAATSPPK"
     gene            complement(16769..17251)
                     /locus_tag="P0D74_RS00490"
     CDS             complement(16769..17251)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574788.1"
                     /locus_tag="P0D74_RS00490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_275460767.1"
                     /transl_table=11
                     /translation="MRDLVRDVVAEHAAHELPLVDSLRTLDDDRVVRTLARRGPRREPL
                     GFGYAEVSAVVAPVVWLVLDQAARRTVDHATEGLLARGQAGVRRLLRRAPATANRTLAV
                     LDPGELALVRAHIVEQATERGLDRPVAEALADGVVARIATAAAVDEGHPETPGTTS"
     misc_feature    17323..17338
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.24"
                     /tool="antismash"
     gene            17455..18003
                     /locus_tag="P0D74_RS00495"
     CDS             17455..18003
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003999362.1"
                     /locus_tag="P0D74_RS00495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YciI family protein"
                     /protein_id="WP_275460768.1"
                     /transl_table=11
                     /translation="MEFLCYHRDRIGSLPLREELLTEHWVYMDRYAEEMIARGPTFAAD
                     GDTPSGSLHVLDLPDPAAARAFAFDEPNYQAGVYRDVLLRRWRNTLGRTMWDFPGGRLG
                     GNRYLVLGLGTGDAADLAPPSDRDELIAYGPLLSDDGSTWLGTAALLRAPDPLSARAVL
                     SPDRYADIEVHDWEFGGRR"
     gene            complement(18106..19365)
                     /locus_tag="P0D74_RS00500"
     CDS             complement(18106..19365)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003960395.1"
                     /locus_tag="P0D74_RS00500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_275460769.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.4e-63, bitscore:
                     213.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVNTDETFVIVGGGLAGAKAAETLRAEGFGGRVIVLGDEGERPYE
                     RPPLSKQFLAGKADRDSVFVHEPDWYEQADVELRLGQPVVHLDRVAKAVRLDDGTSVRY
                     DRLLLATGAEPRRLDVPGADLAGIHHLRDLAHAEQLREVLTEVGRDQGQLVIAGAGWIG
                     LEVAAAARAYGAEVTIVQPSPTPLHRVLGPELGAVFRDLHAEHGVRFHFGTRLTEIVGQ
                     DGTVVSVRTDDGAEHPAHALLVAVGAAPRTALAEAAGLAVVDRADGGGIAVDAALRTSD
                     PFIHAAGDVAAADHPLLDTRLRVEHWANALNGGPAAARAMLGQDISYDRVPYFFSDQYD
                     LGMEYSGYAPPGSYDQVVYRGDVGKREFIAFWLHEGRVLAGMNVNVWDVAEQIQQLIRS
                     GTPLGPEQLADSQVPLDSLA"
     misc_feature    complement(19515..19529)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.85"
                     /tool="antismash"
     misc_feature    19844..19853
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.12"
                     /tool="antismash"
     misc_feature    19879..19893
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     misc_feature    complement(20015..20030)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.6"
                     /tool="antismash"
ORIGIN
        1 actgtggggc ggggcgcgcg gagccgtccg cgaccatgcc ctggagcagt tcgagcgccg
       61 tcgcgggatc gcccaggagg ctgtcgccga cccgcgccgc ggcggcgacc tccggatcgc
      121 cggtgatctg gaggagctgc gtgccggcgg ggaggaagtc gccgggaacg taggggtagt
      181 accggaacac ctcggcaccg atcacgacca ccagatcgtg ccccgccaac ctgtcgctga
      241 cggccttcac ggacatgccg agcgggccgc cgaagagggg gtggtcctcc gggaaggagg
      301 cgcggtccag cagcggtgcc ccgtagacgg cggccctcag cctctccgcc aggttcacgg
      361 ccgcgtccca gccgccgctg cggtcgacct ccgggccgaa gaccaacgcc ggacggttgc
      421 tcgcggagag gcgctcggcg aatccacgca ggcgctcggt gtcgggggcg acgcggtggc
      481 tcaccgtccg cacccggtcg aagcccgacg agggccgctt ccagtcgtcc atgggaatcg
      541 acaggtagac cggtcccgcc ggtggctgta gcgcctgcgc ataggctcgc atgaaggcgt
      601 ccgggacgtc ttcggcacgg gccggctcgt aggaccactt cacccacggc ttcggcagcg
      661 tggtggcctc gcggttgccg aggtagggct ccccgatcac cagctcccgg tgctgctgcc
      721 cggacgtgac gatcagtggc gtgttgccgt ggtaggccgc gaccaggttg cccacggcgt
      781 ttcccagtcc ggccgaggag tgcacgttga ccagtgcggg acggcgggtg acctgggcga
      841 acgtatcggc catcgcgatg acggacgcct cctgcagcgc caggacgtag gtgaagtccg
      901 cggggaactc ctggaggaag ggctgttcgg tggagcccgg attgccgaag accgtggtga
      961 ggttcagggt ccgcaggagg tcgtaggtga cgctgcggac ggtgggttgt tcggacatcg
     1021 ttgccaccga cttccgtgct ggagctgcgc gcccggtcaa cgtccctgac ggggatgtcg
     1081 gcgccgttcg ttgaaggccg gcgcgccgcc ttccacatcg tgtgggggcg gaatcggcgc
     1141 gcccgcccga tcctgcttga tcggaacgcc ctcgtcacgc actgtggtcc gttcgatggg
     1201 ggttcgggtc gcgcatgtcc gccgcggcgg cgggtacgcc cctgtcgcac gggatgtggt
     1261 ggaagtgacc ggagagcgag ggctgtcgga agtgataccg aagctgcaag cggtcgcgct
     1321 ggactgcgcc gacccggtac ggctcgcgga gttctacgcg gaactgctcg gcggccgggt
     1381 ggtcgcggac ccggaggatc ccggatgggt cgaggtgcag gggttcgagg ggacgccgct
     1441 ggcctgccaa cgggtggacg gctaccgacc acccgattgg cccggtcaac agcgcccgca
     1501 acaactccac ttggacttcg acgtggacga cctcgacggg gaggagaagc gggtgctcgc
     1561 cctcggcgcg accgtcttgg agcgcacgga ccagatccgt ccgggggcca actggagggt
     1621 ctacgcggac ccggcgggcc atccgttctg cctctgcctc cactgaccga gccgcccccg
     1681 ctcacgacga acgggcgggg cggcgcggag ccccctcggg cgcatgggcg cccggacgag
     1741 ggcgccccat gcatcgcccc gccgccccct cctccggcct cgtacgtggg cgccgccgac
     1801 ttcaccgcgg cgggcgccgc agtccctcgg gcaccgcaca ggcaggccgc tagacggtga
     1861 cctcccgccg ggccaccgcg accagttccg ccgccggccc caccagtcgc cgtccggtcg
     1921 gccagaccgc gcgcaggtcg cgggtgaggt cgacgcccgc cgcctcgacg ccggtcagcc
     1981 gaccctcgac gatgtccccg cggacggcca gctcgctcag gaccgacggc ccggtgccgg
     2041 cgatcacggc gccgcgcacg gcggccgtcg agccgagctc gaccaagggc cgcgcacggt
     2101 cgcagccggc caggtgcagg gcgcggtcca gggtctgccg cgtgccggaa ccgctctccc
     2161 gcagcaccag cggcgtgcgg gacagttccc gtgccgacag cggctcgcgg cgacgcgccc
     2221 acgggtggcc ggggtcgacc acgacgacga gccggtcctc ggccacctgc cgcgtggaca
     2281 tcacgcggga caggcgcggt ccctcgatga acccgatgtc ggcctcgccc gcttcgacca
     2341 gttcgggcac gtgctcgctg ttggtcacct gcagcccgat gtacagctcc ggccgacggc
     2401 tccgcagttc gctgatccag gtcggcagca ggtactcggc gatggtgagg ctcgcggcga
     2461 cgcgcagttc ggcctcccgc cgatcgcgca gcttgccggc cccggtgagc agatcgtcca
     2521 gttcggccag gacggaccgg gcgtgtcccg tgacgacctg cccggccagc gtcagccggg
     2581 agccgcgtcg ggtccggtcg agcagcacca gtcccagtcc ccgttccaac gtcgacagcc
     2641 ggcggctggc ggacggctgg gagatccgca gccgttccgc cgcacggccg aggctcccga
     2701 gatcggccac gaggacgagg agccgcagcg actccaggtc gggcgtgcgc agggggaggt
     2761 gaacggacgg gcggtcggag gcggagggct ctgtcacagc tccagcgtat gagtcggtca
     2821 tgcgtgcacg ctatgacctc ctgcacgatc gggggctaca gggcgagcac gcggccaccc
     2881 agagtggtga tcatgaagga cgccagcctc ccccggccaa cccgcccacc cgacctcgcc
     2941 cccgcccgga agcccggcgc ggccttcgtc gaccggctgc ccgggctcgc gctcgccgtc
     3001 gcggtcgccc tcgtcgcgac ctcactgggt cggttggtcc ccgtcgtcgg cgggccggtg
     3061 agcggcatcg tgctcggggt gctggtggcg gtcgtggcgc ggcccggcgc ccggatgcgg
     3121 cccggcatcg ccttcgccgg acgcggagtg ctccaggccg cggtggtggt actgggcgcg
     3181 caactgtccc tggggcaggt gctgcgggtc ggtgtcggct cgctgccggt gatgatcgtg
     3241 acccttgcgg tctgcctggc cgccgcgtat ggcatcggac gccgcctggg tgtcgtacgc
     3301 gacctgcgca ccctgatcgg ggtgggcacc ggcatctgcg gcgcctccgc gatcgccgcg
     3361 gtcaccccga tcatcggagc ggccgaggca gaagtggcct acgccgtctc cacgatcttc
     3421 gtcttcaaca tcgccgcggt gctgaccttc cccgtcctcg ggcacctgct gggaatgggg
     3481 cagcacgcct tcggcctgtt cgccggcact gcggtcaacg acatgtcgtc ggtggtcgcc
     3541 gccgccacca cctacggcgg cccggcggcc gactacgcgg tggtggtcaa actcgcgcgc
     3601 accctgctga tcatcccgat ctgcctgggc ctcgccgccc tcgcccggcg ccgcgcgcgg
     3661 acgacggacg ccggcgcagc aggttcgggt gaagggctcc ccagccgggt ccgcgtcggc
     3721 cgactggtgc cgtggttcct cggtggcttc ctcgtcctcg cggccgcgaa caccgccgga
     3781 ctcgtcccgt cggccgcgca cggcccgctc agcgcgctcg cggtcttcct gatcaccgtc
     3841 gccctctcgg ccatcggcct gtccaccgaa cccgccaagc tgcgccgcgc tggcgccgcc
     3901 cccctgctgc tcggcggctg cctgtggctg gtggtgtccg ccaccagctt ggccgtccag
     3961 ttcctgaccc ggtacttgtg aggtcgcgtg caccgatgca cgccggcacg cactgcacgg
     4021 caccgcacca cacagcctcg gacgcgggtg cggagcaacg ccgtcccaca ctggggatga
     4081 tggggggtgg gtgatgcgca tggcggggcg gactcccgcg gagcgggccc ttgcccgctc
     4141 gtacaccacg ggtgacggac ggatcggatt cgccgtctct catctgtcgg tccgtcacca
     4201 ggccgatagc agcgtgtcgt tgacgtagaa ggtcgtcgta gcgcgtcagg gacacgcgga
     4261 cgaacgctga ctgttcacgc tgccctgaga ggacaggtcc ttcgtggacg tcctcacctc
     4321 ccgccacccc gccccgaacg cctccgacaa gacgtacacc tggttcgcgc ggcgttgggg
     4381 agtggtgggg caccaacggg tgcataaccg gcggacggcg aagaggggcc gtcaactgcc
     4441 ctgaggggag ggccaggagc cgcgagcggc ggctgctccg agaagcagcc gccggtcagg
     4501 acgcacgggc ggactccgca ccgaagccga cgtgacggtt cgggccgacg gtcgcgcggt
     4561 cccgcgcgcg ggcccggacg gaggtgacgg ggccggagac cgtgagcacg cggctcacgg
     4621 cacgcgcgcg ccggcctcgt cccgagcggc ctcctgcgac ctcagcgacc cccgccggaa
     4681 cccgcggccg cgaacgacat cgccaccgcg cccgcccggc ccgtcggacg gtacgagtgg
     4741 tgcgccgccc agtcgccgta ggccggtgcc tggacctggc ccgtcacggg gggctgcgcc
     4801 tggctcgtca cgggaggctg cgcctgctcc gtcacgaagg gctgcgcctg gggcgccacc
     4861 ggcgcctgga atcggcgctg cgggacgcgg tgcatctgcg tcttcgcgtg gatcacccgg
     4921 tgcttcgcgg ggtgcacgcc ctgccgcttc ttcatgttct ggatcgccac cgacccgttc
     4981 gccgggttca ccgtgtagcg cacgccctcg tgcgtgacgg accggtgggt cgagctgagg
     5041 gtggcgatct gcttgttctt gagctggatc ttcgccgtgt aactgccgtt gaccttctgc
     5101 acggtggcgc gcgcgccgtt ggtcagcgtg accgtacggg ccgggcccgg cttgttcttg
     5161 tcgtggttgt tcacgccctg cgccctggag tggacgtgcg tgccgtcgaa gtagacgtag
     5221 atgcccttgt tgtagctctg gcccttcttc agggtcgcga acggcttgcc gctgccgatc
     5281 gcctggaggt cgcagacccc gttgtggatc acggcctcca tgccgccgcc gaggccgacg
     5341 gcccggaccc tgtccttggc cggctcctga ggtgcggtgc gcgcggcacc ggcggacgcg
     5401 ggccggtcct gctgctccgg ggtgcccacc gcgaacgcgg tggtcggtac ggccatcgcc
     5461 ccggcgagca cagcggcggt gcagacggca cgcagggagg cgtgcgaggc ggggaagatg
     5521 cgggaggtct tcatggagct cgtaaccctt ctcgaggtgc aaagcgcgtg aagcggttca
     5581 ccgaacctgt acaaaacgac ccattacgga tcaatttgga cagctcggga tattagacaa
     5641 ggttccctcg acgggaaggg cgaggcgcgc ggtgtgcgga cgcggcttgc ggctcttggc
     5701 cccatcgaaa tccggcagcg ccgcacgaga ccgcgtgaat gccggcgagc ggcgggtcgg
     5761 ccccgtgccc cctggatacc gcccccgaag gcagacgcac tcgggccagg gccccgaaca
     5821 accacctgac gcccgtgggg agttcaggag ttcaggcgtg aacgagttca ggagttcgca
     5881 ccggggccgt acccgtttcc gccggctgcg actgcccgcc cgggccggca gacgccctcg
     5941 cactccgaaa ggagcgaccc gccccctcag gcgcctagtc aggtaatagc catatcgcat
     6001 ggccttccac ggcggctccg gcggtccccc tgatgcttgc cggcatatgg gaatcatcgt
     6061 cctggcaagt gccgcccacc tgcgtccacc cccgccggga aagcacggtg acggcatgcg
     6121 cgctcggtgc gccgacgatc ggccggcagg tcagcgcgac tggcgcaacg aagacgcccc
     6181 gccccgggct cggcgtgggg cggagcgtct tcgccgacct gcggactgcc ggacggggcg
     6241 catgagtcgg cggcgcccgc ctgaatgtcg tcaaggggtg tagacggcgt cgctgccgta
     6301 cagctccttc gtgaagctgg agaggtagtc gtgccggtcg gaaccgtcca ggtcgtacgt
     6361 caggtacacg ccgtagcctt cgcccacggt gcgccgggcg aagtcggctg cggtgcccgc
     6421 aggcgtggca ccgatctgga cggccgccgg ggacaggctc gacttgggca gcgagatgcc
     6481 cggcacctgc cactgcccgt accaggggtt ccaggcgtag ttgaacttcg aggtgatgtc
     6541 cacgccgccg taggacagct tctccgccga cgggccgatg ctgtacaggg agatgagctt
     6601 gtcgggcatg tagtcacgca gtgcggagac caggtggacg aaggaactgt cgttgggttg
     6661 cccggtgccg ttcttcccgt actcggcgta ctcgtcgtcg aagtcgatgc cgtccaggcc
     6721 gtacttgccg acggcgtctg acaactgctt ggcgaacgcc gaggctgctt ccttggacgg
     6781 gaagttggcg aagccggccc cttcgtggtt gccgagcacc gacagcatga ccttgatgcc
     6841 cttggcctgc agcggtcgga tctggtgggc cgcatcgtcg aggacgcgct gcacgttctc
     6901 gttgaagtac aggtaggccg acttcttggt ggtgtcgtag ttgatgttgg cggcgaagat
     6961 gaccgcgacg tcgaacacgt tggcgccgcc cttggccagc gtgtacttgc cgacgttgag
     7021 catgctgttg ttgttcacct cgacataggc gaccgaggtg ggacccttct tgaccggtgc
     7081 cgcagccgca gggctggcgg ccgccttggc accggccgag agtgccgcta cgagcagaag
     7141 cgcgaacgca gccgtgcgcg ctctgcctcg acctaaagcg aaagtcatgg accaatctcc
     7201 tgtcgatggg gtggcatcgt gaacttgccc cagttgaagg ggccttaggc gatgcgcagg
     7261 tcaacgggcc ctgagggctg ccgctgtgct cgccgggccg gcggggtaat cctggagctc
     7321 cgtttccaca ggtcgggacg aggtgacgcc ggtggccggt tcccctgacg gtcgacgcca
     7381 ccccaagcca aggacccggt ccaagtcccg cgccaagtcc cgtgccaggt acggcctatc
     7441 ggtggattct cggcacgccc ccggaatcgt cgaggtcact ggcgggggtg agtcctgttg
     7501 tcgagtggcg cggtcgttgg ggcgccgcag aggcgtttca cggaggccat tcggaacttt
     7561 tcggcccagt ggggcatctc ctccagtgcg tgcccccaca agcgaggagc tgttccggat
     7621 gatgcgtcga gttcgtgtgc tgctggtgag caccgtggtg ctggtggcgg gggcggtgat
     7681 gtcgtcggcg ccggcctccg ccgtgatcgg cgggtcgaag agcacctacg ggccgtgggc
     7741 ggtgcggatg ctcgtcgacg ggaaaccgac gtgcaccggg acggcggtcg caccccagtg
     7801 gatcatcagc gcttcgcact gcttcttcga gcaggcccag ccggtcgccg acaagcggat
     7861 ctcgttccgg gtcggcaacc tcgacatgcg aaagggcgtc accgtccgcc cggtgcccgg
     7921 tcgacgcgtg ggaagcgcgg acgccgacat gatgctcatc aaggtcccgc cgatgaaggt
     7981 ccgcacggcg ccgttggcca cggccggggt ccaccagggg caagtcgtgc gccagtacgg
     8041 gtggggcgcc acctgcaccg gggacgagaa cacctgccag tccccggtgc tcaagcagtc
     8101 ggacctgcgg gtcgtacggg cggacgaccc tcgttgcgag ggtcacaccg cgccgggcgg
     8161 ttcggacttc tgcatggaga aggtggccgg gattcccgcc ggtggcgact ccggaggtcc
     8221 gatcatgagc atcggtccgc gcggcaccga gatcctcgtc ggcgtcttcg acggttccga
     8281 ccgggaggag atcgccgagg ccggcgaggt ctcccaacaa cttgcctgga tccgctcggt
     8341 catccagcac taggcatgtc cgatgcgtca tggccggggc cccggcgccc ggcacggcgc
     8401 ctcgcggcgt tgccgaaacg ccctgacgcg gagcgcgggc gggcggggac gccgccgccc
     8461 gcccgcgtgc ggctcggcgg ctcggccgct ccgtgccgcg tcggcccggt caacggaccc
     8521 gccggacccg tcggagccgc ccgcgacacg ccgaacgcgg ctgagataac tgacacatct
     8581 gaggcgtctg aggtttctgt ggcgtttgcg actgtctgaa accgaacgta tggagtcgtg
     8641 ccgcgacggt ccgcccgggc cgggcccgtc ccttccgaag caggcacggc ctggtttctc
     8701 gccgcctcga aaaccggcgg gaatgtttcc ggttcagttc taccggtggc ggaattcgat
     8761 actgcggaag gcttaaatcc gcgtcaatgt gacgaaggtt ctcccgatcc cccttgtctg
     8821 gccggatctt gagctggtac acctgatccg aaaattgttt cgccgaactg aatcgaaccc
     8881 agccaccggc ccgtcgagtg gaccggtcgt gaatccagcc gcaggtcgat cgacgttcca
     8941 ttcctgctgc tggcgaccgt gccctggaac cgtccggacg agcgagcacc ggcgagacgt
     9001 cagccaccag aattgccgca cagcggccgg tgataagtgc gcccaaaaag aaggggattg
     9061 atgttaactc aaagttcatc tgaatcgccg cccgaaccct tggcggacgc gttgacggtc
     9121 ctcaagaccc gtaccgcggt ccgcaactat tcgaaggagc cggtcgacga cgcgctgatc
     9181 gggcggctgt tggaggccat gctcgccgct ccgaccgcct ccaatcgcca ggcgtggtcc
     9241 ttcgtggtgg tgcgcaggcc cgccggggtc cgccaactgc gcgcgttctc gcccggggtg
     9301 ctgggaacgc ccgccttctt cgtcgtggcc tgcgtcgacc gcagcctcac cgacaacctt
     9361 tcgccgaagc tctcccagac gatctacgac accagcaagc tctgcgtcgc catggcggtg
     9421 gagaacctcc tgctcgcggc gcacgcgttc ggcctgggcg gatgcccggt gggcagcttc
     9481 aggtccgaga tcgtcaagag catgctcggc atcccggaac acatcgagcc catgctcgtc
     9541 gtcccgatcg gccgtcccgc gacggcactc gtctcgtccc cccgccgcgc caagaatgag
     9601 gtcgtcaact atgaatcctg gggaaaccgt gctgccgccc caactccgtg aggacatcgc
     9661 actcctcgcc gcgtttctgc tcagcagcgg tcgcggactc ctggacgagc cggccgacta
     9721 cggcatctac cgttgcaccg acggggcccg ccgggtgctg caactcctgg acgaacacgg
     9781 gggcagcacc gcgcgtctga ccgccgtgcg cgaacgcctc gacgaggtca tgttcgcgcc
     9841 gatgggcgag gaccgggaca tgggcgagat tctggacgat ctgtgtcgcc aaatggcagg
     9901 cgccctgccg gaaatcgaaa caccctgaca ttcgtccggg gcaaccccaa aaggatttta
     9961 tagcatgcta tcaggcttag ttcccgcgct ggaccacagc atgcgggaag aaatacttgg
    10021 caatcgcggc cgaaagatcc ggcaacgcgg tgagcacgct ctcattggaa tcagtgcggg
    10081 caacagttat ttcagccaga agaacgtcac catgctgctg caatgggccg ggcagcattt
    10141 cgagcgcacg gatgtcgtct acgtggacac gcacatcgac gacatgctga tggcagacgg
    10201 ccgcagcgcg caggaagccg agaggtcggt caagcgcacg ctcaaggatc tgcggcgcag
    10261 gctgcggcgc tcgttggaaa gcgtgggcga ccacagcgag cggttccgcg tccggtccct
    10321 gtccgagctc caggagaccc ctgagtaccg ggccgcacgc cagtccaccg accgggcctt
    10381 ccgcgaggac ggcgagttcg ccaccgtctg cgaggagatg gtgcgcgccg tggtgatgaa
    10441 ccggcccgtt gacggcgtcg gcatctcgga ggaacacctg cgcgccggtc tgaactacgt
    10501 gctcgccgag gccccgctct tcgcggactc gcccggcgtg ttctccgtcc cctcgtcggt
    10561 gctctgctac cacatcccca ccccggtatc gacgttcctg gcccatcgcg agaccggttt
    10621 ccaggcggct cagggtcagg cgtacgtcgt cgtcaggccg caggaactgg ccgacgcggc
    10681 ctagccaggc attccccagc cggacacctc acgccccctc ccctcaccat ccctcccggt
    10741 gccgccgccg gaattcggac gcgtcacggg gagggcagga ggcatgcttc cgctgtggaa
    10801 caggtgcgaa ggaggagtga gttggtgcgc ccgctgctgt tggtggacgt ggacggaccg
    10861 ttgaatccgt atgtcgcgaa accgcagcgg cggcccgcgg gctatcagac gcaccgtctg
    10921 ctgacgcctc gctgggaggc cgcccagcgg cgtcggctgg cggagtgggg aacgccggac
    10981 gcgcgcgtga aaccgctgcg ggtgtggctc aacccggagc acggcccggc gttgcgctcg
    11041 ctcccgttcg acctggtgtg ggcgacgacg tgggaggacg aggccaacgc ctacgtcgcg
    11101 cccgtcctgg ggttgccgga cctgccgttc atcgcctggc cctcgccgcg gcccgagccc
    11161 gagggcgggg tgttctggaa gacgccggcg atcgtggcgt gggcgagggg ccgggcgttc
    11221 gcctgggtgg acgacgacat cacacgggcg gatcgcgcct gggtggcgga gcaccacgac
    11281 ggccccgccc tcctgcaccg ggtcgacccg cggcacggac tcaccgtcga cgacttcgcg
    11341 acgctgacgg cgtgggcgag cggcctcggg tgacgcggcg ggcggacggg gggccgccaa
    11401 cccaccggtt cgcggtcgtc gcccttgccc acagcggtgt tcagcgtgcg gtcgcggtcg
    11461 tccagtccgg tgtccagtcc ggtgtccagg tgccggtcgc gtcgtggtcg gccgccgtgc
    11521 cggcgaggtg ggcgcggagc gcggccagcg cggggtgcgg gttgtcgcgg tgccacagca
    11581 gcgcatgcgg gtagaccggg gtcgggtcgg tcaccgggat gcggcgcagg ccgtggtcgg
    11641 cgggccagac gaggcgggtg tgggcgccca tgaaggtggc cagggccggg gtgtcggcga
    11701 cggtgtcgag gagcgcgtcc gaaccgaagt tggggccggt cgcctcgatg gtgaggccga
    11761 actcggcgac gaggtcgtcg tagtaggcgg cccactccgt cccggggacg atgccgggca
    11821 tccagatccg gtgcccgacg agctgcgcca tggtcaccga ccgggcgccc gccagcgcgt
    11881 gggcgggacc ggtgaggagt tggagcggct cgtcgaccac ccggacggac tcgatgtccg
    11941 ggggaagggg gcgaccgggc acgccgacgg cgcggaacga cgcgtcgatc gcgccggacc
    12001 ggagggcggc gacggccgtg tcgatctcga acagcaacat cacgtcgagg tcgatctcgg
    12061 gatgggcgcg gtggaagtcg cgcatcaggc ccgaggccgc accgcgcgag ttgatcacgt
    12121 cgacgcgcag gggacggcgt ccggcgcgca cggaggcgac ggcccggtcg gcgacgcgca
    12181 gcagctcccg ggcgtggggc aggaacgcct gcccgtcgat ggtgagctgc gccccgcgcg
    12241 gggtgcgggt gaacagtcgc acttcgaggt tgcgctccag cgcggcgatg cgtttggaga
    12301 cggcctgctg ggtgacggcc agctcgacgg cggcctcctg gaattgcccg gcgtcagcga
    12361 cggcgacgaa ggtccggact gcttcgagat ccacggtcac cagcctactg gaacaaccac
    12421 tggttgtagc aaggtggccc cagggttgtt tgtcgtcggg ctatgacgct cgctttgata
    12481 cctccgatcg cggatcggtt gtacgggtga gtggtgaggg cgtcgaacat ggggaacggg
    12541 catcggctgg gccgtcggtt cgggtggctg tggggggcat acggggccag cgcgctcggc
    12601 acctggctcg ccttcggcgc gttcccgctg atcgcgatcc acgtgctgca cgccgggccg
    12661 gcgcaggtcg cggcgttgtc cgccgtgggg gccgcggtgg gcgcggccgt ggcggtgccg
    12721 ctcggcccgt gggtggagtt ccggcgcaag cggccggtgc tcatcggcac ggacctcgta
    12781 cggttcgccg cgctgctgac gatccccgtc gccttcgcgt gcggcgtgct ctccttcgtc
    12841 cagctcctgc tggtcgcggt cgtcgtctcg gcggccgaca tcaccttccg cgccgcctcg
    12901 ggcgcgtacc tgaagacgct ggtgccggcc gaggacctgc tcgtcgcaaa tgcccggttc
    12961 gagtccacga cgtggacgac cacggtcgtc ggaccgccgc tgggcggcgc ggcgatcggg
    13021 ctcctcggtc ccgtggcgac ggtggtcgcc gacgcggtca gctacctgct ctcggccctg
    13081 ggcatccgcg cgacgggcgg cgacgagccg cggcccgagc gtcggccggc cgcgcggctg
    13141 cgggccggtg acctgctcga cggctggcgg tacatcctcg ccgaccggac gttgcgcccg
    13201 ctgttcttca acaccgcgct gttcaacggg ctgctgatgg ccgcggatcc gctgctcgcc
    13261 gtgctgatgc tcgggccgct cgggttctcg ccgtggcagt acgggctcgc cttcgccgtg
    13321 ccctccctcg gcgggctgct cgggtcacgg ctggcccggc cgctcgccgc gcggttcggg
    13381 cagcaccagg tactggtcgc ggtcgggacg ctgcgggcgc tctggcccgt cgggctggcc
    13441 ttcatcgggc ccggcaccgg gggcctgctg ctggtgatgg gcgtcgaact cggcctcatc
    13501 ttctgctgcg gggtcttcgg ccccgtctac gccacctacc gcctcgaacg caccgcgaac
    13561 gaccggatcg cccggacgct gtccgcctgg tcggtgacga ccaaagccgt gaccgcgctc
    13621 ctgacggccg tatggggcgc actggccggc ctcctcggcc cgcgcaccgc catcggcctg
    13681 gccggcgtgc tcctgctggc gaccccgctc ctgctccccc gccgtgccgc accgccccac
    13741 gccgcacccg agccagcgcc ggcaccagcg ccggcgccgg cgccggacgg cgcctgacgg
    13801 gccaagcgga cgcccgtgcc cggcgacgcg tccccggacg ctacttgggc ggcgaggtgg
    13861 cggcctgctt gatgtcgagg accgcggtgc cgaaggtgcg catcgcgttg acgacctcgt
    13921 tgagggacgt ggtgaagagg cgctcgcgtt ccgcatcggt ccggtgcggt gcgctcttgg
    13981 gcgggacggt cgcctcctgg cagtccgtcg ccccgcggtg gagttggtcc agtgcggcgg
    14041 accagttcct ctgcaggtcc cggtccggaa cggggaagta ggcacgcgcc tcctcgacgc
    14101 gctggccgag ggtgccgcag cggcggtgga acgcctgctc gtccagcgcg accgtcccgt
    14161 cggcgttgcg cttgccggcg gcggccttga ggagttcgga gtccagggcg atcgaggcgg
    14221 cgttgatctg ctgggcacga agggtgccgc cggcgttcag ccaggacgcc gcctgccagg
    14281 cgcgggtctg cggggtctgc gccggcgggg cgggcccgcg ttgtttgcgg accgcgtcgg
    14341 ccgcctcctg ccactggcgg gagtcgtcgg aggcagctgc ctgggtgaag gtcacggcgg
    14401 ccagcaccac cgccggcagg ccgagcgcga ggagcgttcc cgctttcagg agcgtcgagg
    14461 gcgggcggtc cgccggactc ggcaccggta cggcggcctc gtgcgccggg ggtcggccgc
    14521 gcaaccggcg caccgcccac gccagtcccg cgcccaccaa cgccgcgcag gccgaaccga
    14581 ggacggcgtt gacgagcgtc aaggaggtga cggtgccgtc gatggtcagg ccgttgcggg
    14641 ggcgccaccg gcacacgtcg aaggcagtgt tcaacgggcc caggcagccg tcgacggaga
    14701 agagggcgaa cacctcggcg taggcgagca gttggacgac ctgcgcggcg atcagcgccc
    14761 gcagcagcca gtgccgacgt gcgccggcgg ccaccaccgc ggccgtcagc aggcaggccg
    14821 ccaggaccgt cacggtcacc caccacatgt ggacgaggac gaaggggccg gccggctcct
    14881 tcggcgtcgc cggccgcgac tggttcatcg cgacctgggc caggaccagg cccatcccgc
    14941 acaccagggc cccggcgaga ccggcgccga gcgtccgccg cagccgcagg gccgtgcccg
    15001 tcggaccccc gaccgtgcgc cgcacgcccg ggagcaggac cagcgccagc ggtaccagcc
    15061 acagcgacag cgtggcgacc ccggcgagga ggtcaccgcc cagcggggtg aggaccatga
    15121 ggccggtgga gaacgccaag aggtccgggc cgtagccgtg ccagtcgccc gggaccgtcc
    15181 gggcgtagta cgcggccagt tccgcacccc ggtcgccgat gcccagggag aggctttcgc
    15241 ccgccacccg ccaccacccc agcccggccc acagcaccgc ggcggtcacc gccgcgcagc
    15301 aggccgcggc cgcccagcgg tgtccccgcc tgggcagggc gagtgccagg cgcagggact
    15361 gggaccacca caccgcgggc accgccgcga tgagcaggaa cgcgagcagg tattggggct
    15421 gcggcagcat ccagtcgagc cggtactggg tgctggcgac gaactggccc agcagcaggc
    15481 cgaggccgag ccagaggccc gccaccgtgg cggacggccc gtgcccgtcg gccctgcgtg
    15541 agccgcgcag gagcgggagg ccgagggcga ggcagagcac cggtgtcacg gcgccgaccg
    15601 tgatccagat cgagcccggg ccctcggaca ggaccggaag cgtcatcagg gactggtaca
    15661 gcagcgccgc cgagacgccg gtgaggaaca tcgccagggc actgacgcgg tcgaggcggc
    15721 cggcgtcgac gagcgcgcgt cggcgttccg cccactgcgg atgggttccc agcagcgcgg
    15781 tcagccggcg cagccacggt gccaccggcc cggtgggatc ggggtgttgc cagctggcgg
    15841 agtccgcgcc ccaggcaact gcccggcgat cggcgaacag ttcgcgccgc cgcagcaggt
    15901 cggcccgcgc caggtgcacc agcgcggcca gcaccagtcc gaccagcgcg ggggccaaca
    15961 gcatggctgc gccgccgggc caccaggggg acttgacgcc ggacagtccc agggcgagga
    16021 cccagccggt ctcggcgaag gtcgggatga gggcgagcag cacgtaggcc cgccacaggg
    16081 cggtgctggc gtaggcgtag tccacgtcac ggtggtgcac gtgggcgagt tcgtgcagga
    16141 cgacggcgcg gaagcccgcc gggtcggtgc ggagtcgggg cagcaggccg gagtgcaggc
    16201 agacggtgta gttgccggag cggccgtgga cgctggcgcc ggaagtcgtc cgcgcggggt
    16261 cgacgcggaa gcgcagccgt gcgcggatcc cggtgcgggc gcacagtgcg gcgagctcgg
    16321 cccgcagcgt gccgtcgagg tcgacggctt cgagcggcag catccggcgc caccgctcgc
    16381 gggccgccgg cagccaccag tacaggccgg ccgcgagggc gagcagcacc acggtggcga
    16441 gggcgccgcg gtacgggacg agcgtgtggt cgccgatgca ctggtacagg gtgcccggcc
    16501 gggtcagggc cgtcaggagg ttctgcggat cgctgctgcc ggggtcgaat ccggcggcgt
    16561 acaggcaacc cgacgggccg tgcagggcct cccggccgtc gcgcaggccg aggagcgccg
    16621 gggcgctctg gagcagttcg tcgagcgtgg ggatgctcga caccacgacg aggaccatca
    16681 acagcgcgaa gcggggaccc gtcccggtcg cgctccggag cccggcgaac gccttcacgg
    16741 caccctgccc ttcacgacgt ggcggccttc acgacgtggt gccgggggtt tcggggtgcc
    16801 cctcgtcgac cgcggccgcc gtcgcgatcc gcgccacgac gccgtcggcc agcgcctcgg
    16861 cgaccggacg gtcgaggccc cgctcggtgg cctgttccac gatgtgcgct ctgaccaacg
    16921 ccaattcgcc gggatccagc acggccaggg tgcggttcgc cgtggcaggg gcgcggcgca
    16981 ggagcctgcg cacgccggcc tggccgcggg ccaacagtcc ctccgtggcg tggtcgaccg
    17041 tgcggcgggc cgcctgatcg aggacgagcc agaccaccgg ggccaccacc gcggacactt
    17101 cggcgtagcc gaaaccgagc ggctccctcc tgggcccgcg ccgcgcgagg gtgcgcacga
    17161 cccggtcgtc gtccaacgtc cgcaggctgt cgacgagcgg caactcgtgg gccgcgtgct
    17221 ccgccaccac gtcccgtacc agatcgcgca cataccgcac cgtgcaaccc ccgtacgtag
    17281 ccgtccagtt gcttgcattg cagcaccaaa gggggacgaa gggtacccct ggggggacac
    17341 ggtgacggtc cgtaggcaac ggcgcgtggc ggcgcggagc gcacggcccg gtgtggggat
    17401 gcggcagccc accccctcaa gaggacgaca tggccccgtg ggggaccatg ggccatggaa
    17461 ttcctctgct accaccgcga tcgcatcggc tccttgccgc tgcgcgaaga gcttctgacg
    17521 gagcactggg tgtacatgga ccggtacgcg gaggagatga tcgcccgggg cccgacgttc
    17581 gccgccgacg gcgacacccc ctcaggcagc ctgcacgtcc tcgacctgcc cgatcccgcc
    17641 gccgcccgcg cgttcgcctt cgacgagccg aactatcagg ccggcgtcta ccgggacgtg
    17701 ctgctgcggc gatggcgcaa cacgttgggg cgcaccatgt gggacttccc cggcggccgg
    17761 ctcggcggca accgctatct ggtgctcggc ctgggcaccg gcgacgccgc cgacctcgca
    17821 ccgccgtccg accgggacga gctgatcgcc tacgggccgc tgctgtccga cgacggctcc
    17881 acctggctgg gcacggcggc gttgctcagg gcaccggacc cgctctcggc ccgcgccgtg
    17941 ctgtcacccg accggtacgc cgacatcgag gtgcacgact gggagttcgg cggacgacgg
    18001 tgaggggcgc ggcggtcgag gcgggccggg ccggcgaccg cgaccggctt cgcccgatcc
    18061 gggcgccggc ccgccctcac cgccgcccga gcccctcgac tcgcctcacg ccaacgagtc
    18121 cagcggtacc tgggaatcgg ccagctgctc ggggcccaac ggagtgccgg agcggatgag
    18181 ctgttggatc tgctcggcga cgtcccagac gttgacgttc atgccggcca ggacgcgtcc
    18241 ctcgtggagc cagaaggcga tgaactcccg cttgccgacg tcgccgcggt agacgacctg
    18301 gtcgtaggag ccgggcgggg cgtagccgga gtactccatg ccgaggtcgt actggtcgga
    18361 gaagaagtac gggacgcggt cgtagctgat gtcctggccg agcatggcgc gggcggcggc
    18421 ggggccgccg ttgagggcgt tggcccagtg ctcgacgcgc agccgggtgt cgagcagggg
    18481 gtggtcggcg gcggcgacgt cgccggcggc gtggatgaac gggtcggagg tgcgcagcgc
    18541 cgcgtcgacg gcgatgccgc cgccgtcggc gcggtcgacg acggccaggc ccgcggcctc
    18601 ggcgagcgcc gtgcgcgggg cggcaccgac cgcgacgagc agcgcgtggg cggggtgttc
    18661 cgcgccgtcg tcggtgcgga ccgacacgac cgtgccgtcc tggccgacga tctcggtgag
    18721 gcgggtgccg aagtggaagc ggacgccgtg ttcggcgtgc aggtcacgga agactgcgcc
    18781 gagttccggg cccagcactc ggtgcagtgg ggtgggtgac ggttggacga tggtcacttc
    18841 cgcaccgtat gcgcgggcgg cggcggcgac ttcgaggccg atccaaccgg cgccggcgat
    18901 cacgagctgc ccctggtcgc ggccgacctc ggtcaggact tcgcgcagtt gctcggcatg
    18961 ggcgaggtca cgcagatggt ggatgccggc gaggtcggcg ccggggacgt ccaggcggcg
    19021 cggttcggca ccggtggcca gcagcagccg gtcgtagcgg acggaggtgc cgtcgtcgag
    19081 ccgcacggcc ttcgccaccc ggtcgaggtg gacgacgggc tggccgaggc ggagctcgac
    19141 gtcggcctgc tcgtaccagt cgggctcgtg gacgaagacg ctgtccctgt cggccttgcc
    19201 cgcgaggaac tgcttcgaca gcggcggacg ctcgtagggc cgctcgcctt cgtcgccgag
    19261 gacgatcacc cggccgccga agccttcggc gcgcagggtc tcggctgcct tggcgccggc
    19321 cagtcccccg cccacgatga cgaacgtctc gtcggtgttc accacttgct gcctcctcgt
    19381 tgcccggtcc gtctcgttga cgtgtgtgtg tgcttcctcc gccgacgccg tgggcgccgt
    19441 gcggcggctg gtgcagccgc ctgggcgctg cgtcgacggc tggtgccgag aatcccgcac
    19501 gccgcggcga agccggaaga tgatctccac cagatgggcg catcacccgc gggaagacga
    19561 cgcctggggg tgatgggaga gatgtgcgcg gtgcgcgcgg acgcctgtgg agtggccggg
    19621 tgagtgggac ggggggcagg tcggcgcccg tcgtccaggc cctcgccggg tgggccgcga
    19681 tggttgggga ggcccgggag ggctgcgagg gagtggaagg aagggagagg aagggaggag
    19741 agggcaggtg aagggcggcg gagggtgtgg ggattggccc agttcacggc tgattcgcca
    19801 ggtggtgttg ggtgattgga ggatcatccc accaccttct ttgtgttatt tgccagtaca
    19861 gcgcccagac acgacggagg agactttcgg ccacgccgcg agccgttgat ccggtgcatc
    19921 cgatacatcc ggtgcatccg ttgggccggc gtggacacgc acatcgacgt agcacgggag
    19981 gggcagcacg tgagcgtgca gcagtacgac gagatcggtg aggcattcga ggggttcaag
    20041 tccctgccgc tggtgcgtta cggggaggtg ccgagcttcc tgggcatggt cggggacgtg
    20101 cgcggcaagt ccgttctgga cgtggcctgc ggcaccggct tctacagcag ggagttcaag
    20161 cggcgcggcg ccacggacgt cttcggggtc gacatctccg ccgaaatgat cgccgcggca
    20221 agggagttcg agcggcaggc gccgctgggc gtgcgctacg aggtcggcga cgtgggcgag
    20281 ttgcagtccg tcgagcggcg cttcgacgtc gcggtgggcg tgcagtgcct gaactacgcc
    20341 gcggacctcg cggagttgga gcggatgtcc gccaacatcc accggagtct ggtgcctggc
    20401 ggcgagttct tcgtgttcgc ccagaagccc gattacgcgt tcgactgtcc gtccctggac
    20461 aagtacgggt tccgctgcga gccgaccggc gaggtgaccg agatgggtcc gcgggtgcgg
    20521 gtcaccgccc tcctggaggc ggggccgatc agcatcgtcg ccacggcacc gcgtcgcgag
    20581 gtctacgagg agtgcttgcg ggcgaccggg ttcagcgcgg tggagtgggt tccgctggag
    20641 gtgtccgagg ccggcatccg tgagttcggt gaggagttct gggc
//
