LOCUS       NZ_JARDXE010000047      6144 bp    DNA     linear   CON 01-APR-2024
DEFINITION  Rhodococcus qingshengii strain HQ HQ1_scaffold47, whole genome
            shotgun sequence.
ACCESSION   NZ_JARDXE010000047
VERSION     NZ_JARDXE010000047.1
KEYWORDS    WGS; RefSeq.
SOURCE      Rhodococcus qingshengii
  ORGANISM  Rhodococcus qingshengii
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Rhodococcus; Rhodococcus erythropolis group.
REFERENCE   1  (bases 1 to 6144)
  AUTHORS   Hu,J. and Xu,J.
  TITLE     A novel hydrolase synthesized by Rhodococcus erythropolis HQ is
            responsible for the detoxification of Zearalenone
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6144)
  AUTHORS   Hu,J. and Xu,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) Grain and Oil Risk Assessment Laboratory,
            Jiangsu Academy of Agricultural Sciences, No. 50, Zhongling Street,
            nanjing 210014, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2022
            Assembly Method                   :: ABySS v. 2.1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: GCA_002079265.1
            Genome Coverage                   :: 470.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_029076895.1-RS_2024_04_01
            Annotation Date                   :: 04/01/2024 06:35:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,927
            CDSs (total)                      :: 6,855
            Genes (coding)                    :: 6,768
            CDSs (with protein)               :: 6,768
            Genes (RNA)                       :: 72
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 33 of 87
            Pseudo Genes (incomplete)         :: 63 of 87
            Pseudo Genes (internal stop)      :: 12 of 87
            Pseudo Genes (multiple problems)  :: 18 of 87
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:34:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 6144
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JARDXE010000047.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..6144
                     /collection_date="2022-01"
                     /country="China: Anhui, Suzhou"
                     /db_xref="taxon:334542"
                     /isolation_source="Corn field soil"
                     /mol_type="genomic DNA"
                     /organism="Rhodococcus qingshengii"
                     /strain="HQ"
                     /submitter_seqid="HQ1_scaffold47"
     gene            <1..>6144
                     /locus_tag="PXH69_RS34315"
                     /old_locus_tag="PXH69_34330"
     region          1..6144
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..6144
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..6144
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2:>6144](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..>6144
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS             3..>6144
                     /NRPS_PKS="Domain: Condensation_LCL (10-311). E-value:
                     3.1e-116. Score: 379.5. Matches aSDomain:
                     nrpspksdomains_PXH69_RS34315_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (474-890). E-value: 4.3e-88.
                     Score: 287.6. Matches aSDomain:
                     nrpspksdomains_PXH69_RS34315_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (996-1062). E-value: 1.4e-22. Score:
                     71.6. Matches aSDomain: nrpspksdomains_PXH69_RS34315_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1083-1406). E-value:
                     2.4e-120. Score: 394.5. Matches aSDomain:
                     nrpspksdomains_PXH69_RS34315_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1419-1582). E-value: 9.1e-37.
                     Score: 118.2. Matches aSDomain:
                     nrpspksdomains_PXH69_RS34315_TIGR01720.1"
                     /NRPS_PKS="Domain: Condensation_DCL (1591-1889). E-value:
                     1.9e-112. Score: 367.2. Matches aSDomain:
                     nrpspksdomains_PXH69_RS34315_Condensation_DCL.1"
                     /codon_start=2
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="PXH69_RS34315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_34330"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_275233156.1"
                     /sec_met_domain="AMP-binding (E-value: 2.8e-98, bitscore:
                     315.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-15, bitscore:
                     44.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 4.7e-73, bitscore:
                     231.9, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALTAQVRPVRVPLSLAQQRMWFLNQLDTSSAGNNVPVAITLTGE
                     LDVLGLEQAVADVIGRHEVLRTVYPEVDGVGYQKIVAPADVDVNLAATSVSDSEIVSEV
                     TNFVAAGFDVTAEVPLRAKLFQIKADEHVLVFVVHHISTDGFSMGPLTRDVMTAYYART
                     NGQAPTWTPLPVQYADYSLWQREVLGSEDDPQSVIAQQITYWAQALDGVPEQLNLPGDR
                     ARPAVFSGQGATFEFSIGQELHERLISVGREHNASMFMVVHAALASLLARLSGTTDINI
                     GAPMAGRGESELDDLIGMFVNTLVLRTEVDPSAAFTTLLASARETDLQAFAHSDLPFER
                     LVEVLDPVRSRAHHPLFQVALAFQNLGQNSLALPGLTAAEFEIDETVAKFDLQLTISEV
                     SEGLSATFTYATDLFDESTVRGFAARLMRILNGIATDPATSVGDIEILDASEREVLTSQ
                     RASSGVAQAPLAEILADAAARYPDNVALRYPGTAQAAAGRSMTYREVDEWSSKLARVLI
                     NRGLGAEDLVAVSIPRSVESVLAVWAVSKTGAAVVPIDPHYPADRIAHMLSDSGAKVGL
                     TLDVERPNLADDVEWLVVDGPLGEQMIAGVSGAPIDAEERVRPLTTAHPAWVIYTSGTT
                     GLPKGVVATNAGLASFSVTQAAHYLVKPTSRTLHFASPSFDASMLELFLAVATGATMVI
                     VPPGVYGGDELAEVFRSERVTHAFITPAALASMDPSGLDDLTVVGVGGEAYSPELISKW
                     TTGDGSAASASAPRTFLNVYGPTETTIVTNVSVPLLPGDRMDIGATIGDMAAFVLDTRL
                     NPVPLGVSGELYLSGPQVTRGYHRRPGLSADRFVANPHGNPGERMYRTGDVVRWVAGTA
                     PSTYAVEYVGRNDFQVKIRGFRIELGEIDASLTAHPEVEFAATMGTTLPSGAPALVSYV
                     FTGKHASVTSAELIEFVSRTLPAHMVPASVMVSSDMPLSPAGKLDRKALPAPVFETKEF
                     RAPVTEMEQILSEIFADVLGLDRIGTDDSFFAQGGDSIMSIQLVSRAKARGVVFAPSDV
                     FESKTVAALAEVAKYAADVEAAVVLEELPGGGVGWMPLTPIERFMVERGGSYNRFTQTM
                     TLELPLGVHRTDIVRTLAAVVDHHDMFRSRLISDGRGWGMSVSEPGTVDVEDLLSRVDV
                     DAAADESTIVLTASKGLDEALGRLKPADGVMVQFVWVDFGPTRTGRLIIAAHHLIVDGV
                     SWRIIVPDLVSAAAQMAGASGATGDVAGTTGDVALEPTGTSMRRWAHALSEEAHRDSRV
                     AELDTWRKVLQTPDPVLGKRAYDSAVDVAATVQRISVTVPTQVTETLLTTLPEVFNGGA
                     NDGLLAGLALALIEWRRRAGIDSTSALLQLEGHGREEAVIPGADLSRTVGWFTAAFPIS
                     LDLSEVDLGDAFAGGDSAGRAIKAVKEQLLAIPDKGVGYGLLRYLNEDTRAVLSRFAGG
                     QVSFNYLGRVVAEDLPAGVEGLGWLPAGDFANVSAPEDVDMPANKVVDINAIVNDGADG
                     AVLEASFAYPVGAIDGESVETFAQIWVEALTALAEHSRSVGAGGLTPSDVPLVSVSQRD
                     IDGFENRFGTVTDIWPLAPLQSGLLFHAMLAESSVDLYSVQMILTLSGKVDADRLRTAA
                     QGIIDRYANLRTAFTADDDGTPVQIVLEDVPVPWRNIDLSDIAAVDREAALNEVLTADQ
                     ATHFDMASPPLIRFTFVTMAEGDYRLVVANHHIILDGWSVPLLLQNLLALYATRGDDSV
                     LPRVRSYRNYLAWLVDQDRDRSLTAWADVLSGVEEPTLLAQVTGGQEFTALSQKLNVSM
                     SSETTAALTALAARLGVTANTIVQSAWAVLLGALTGTDDVVFGATVSGRPPALTGVESM
                     VGLFINTLPVRVRLDAAESVGELVARVQIEQARMLDHHYLGLTDVQKAADVGTLFDTLV
                     VFESYPVDREGLAAQADVLDGMMIDDIASDDSTNYPLTLLIALDEQLHLTLRYLPDFFD
                     ADYATALLDRVLRLLSSVATDPSVRVGDVDILDSVERSLVLEGWNDTAREVAGVSV"
     aSDomain        34..936
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PXH69_RS34315_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.10E-116"
                     /label="PXH69_RS34315_Condensation_LCL.1"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="311"
                     /protein_start="10"
                     /score="379.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHISTDG"
                     /tool="antismash"
                     /translation="RVPLSLAQQRMWFLNQLDTSSAGNNVPVAITLTGELDVLGLEQAV
                     ADVIGRHEVLRTVYPEVDGVGYQKIVAPADVDVNLAATSVSDSEIVSEVTNFVAAGFDV
                     TAEVPLRAKLFQIKADEHVLVFVVHHISTDGFSMGPLTRDVMTAYYARTNGQAPTWTPL
                     PVQYADYSLWQREVLGSEDDPQSVIAQQITYWAQALDGVPEQLNLPGDRARPAVFSGQG
                     ATFEFSIGQELHERLISVGREHNASMFMVVHAALASLLARLSGTTDINIGAPMAGRGES
                     ELDDLIGMFVNTLVLRTEVD"
     aSModule        34..4749
                     /complete
                     /domains="nrpspksdomains_PXH69_RS34315_Condensation_LCL.1"
                     /domains="nrpspksdomains_PXH69_RS34315_AMP-binding.1"
                     /domains="nrpspksdomains_PXH69_RS34315_PCP.1"
                     /domains="nrpspksdomains_PXH69_RS34315_Epimerization.1"
                     /domains="nrpspksdomains_PXH69_RS34315_TIGR01720.1"
                     /locus_tags="PXH69_RS34315"
                     /monomer_pairings="X -> D-X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       106..213
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34315_0001"
                     /evalue="7.30E-14"
                     /label="C2_LCL_024-062"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="70"
                     /protein_start="34"
                     /score="44.1"
                     /tool="antismash"
                     /translation="NVPVAITLTGELDVLGLEQAVADVIGRHEVLRTVYP"
     CDS_motif       415..480
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34315_0002"
                     /evalue="1.80E-07"
                     /label="C3_LCL_132-143"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="159"
                     /protein_start="137"
                     /score="23.7"
                     /tool="antismash"
                     /translation="VHHISTDGFSMGPLTRDVMTAY"
     CDS_motif       529..567
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34315_0003"
                     /evalue="1.40E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="188"
                     /protein_start="175"
                     /score="17.5"
                     /tool="antismash"
                     /translation="QYADYSLWQREVL"
     CDS_motif       835..924
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34315_0004"
                     /evalue="6.60E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="307"
                     /protein_start="277"
                     /score="44.2"
                     /tool="antismash"
                     /translation="DINIGAPMAGRGESELDDLIGMFVNTLVLR"
     CDS_motif       973..1092
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34315_0005"
                     /evalue="4.30E-18"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="363"
                     /protein_start="323"
                     /score="57.7"
                     /tool="antismash"
                     /translation="RETDLQAFAHSDLPFERLVEVLDPVRSRAHHPLFQVALAF"
     aSDomain        1426..2673
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PXH69_RS34315_AMP-binding.1"
                     /evalue="4.30E-88"
                     /label="PXH69_RS34315_AMP-binding.1"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="890"
                     /protein_start="474"
                     /score="287.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DAAARYPDNVALRYPGTAQAAAGRSMTYREVDEWSSKLARVLINR
                     GLGAEDLVAVSIPRSVESVLAVWAVSKTGAAVVPIDPHYPADRIAHMLSDSGAKVGLTL
                     DVERPNLADDVEWLVVDGPLGEQMIAGVSGAPIDAEERVRPLTTAHPAWVIYTSGTTGL
                     PKGVVATNAGLASFSVTQAAHYLVKPTSRTLHFASPSFDASMLELFLAVATGATMVIVP
                     PGVYGGDELAEVFRSERVTHAFITPAALASMDPSGLDDLTVVGVGGEAYSPELISKWTT
                     GDGSAASASAPRTFLNVYGPTETTIVTNVSVPLLPGDRMDIGATIGDMAAFVLDTRLNP
                     VPLGVSGELYLSGPQVTRGYHRRPGLSADRFVANPHGNPGERMYRTGDVVRWVAGTAPS
                     TYAVEYVGRNDFQVKIR"
     CDS_motif       1879..1935
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34315_0006"
                     /evalue="7.60E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="644"
                     /protein_start="625"
                     /score="21.6"
                     /tool="antismash"
                     /translation="AWVIYTSGTTGLPKGVVAT"
     CDS_motif       2449..2538
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34315_0007"
                     /evalue="2.80E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="845"
                     /protein_start="815"
                     /score="45.2"
                     /tool="antismash"
                     /translation="PLGVSGELYLSGPQVTRGYHRRPGLSADRF"
     CDS_motif       2638..2700
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34315_0008"
                     /evalue="1.50E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="899"
                     /protein_start="878"
                     /score="36.2"
                     /tool="antismash"
                     /translation="YVGRNDFQVKIRGFRIELGEI"
     aSDomain        2992..3189
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PXH69_RS34315_PCP.1"
                     /evalue="1.40E-22"
                     /label="PXH69_RS34315_PCP.1"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="1062"
                     /protein_start="996"
                     /score="71.6"
                     /tool="antismash"
                     /translation="EQILSEIFADVLGLDRIGTDDSFFAQGGDSIMSIQLVSRAKARGV
                     VFAPSDVFESKTVAALAEVAK"
     aSDomain        3253..4221
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PXH69_RS34315_Epimerization.1"
                     /evalue="2.40E-120"
                     /label="PXH69_RS34315_Epimerization.1"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="1406"
                     /protein_start="1083"
                     /score="394.5"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLIVDG"
                     /tool="antismash"
                     /translation="MPLTPIERFMVERGGSYNRFTQTMTLELPLGVHRTDIVRTLAAVV
                     DHHDMFRSRLISDGRGWGMSVSEPGTVDVEDLLSRVDVDAAADESTIVLTASKGLDEAL
                     GRLKPADGVMVQFVWVDFGPTRTGRLIIAAHHLIVDGVSWRIIVPDLVSAAAQMAGASG
                     ATGDVAGTTGDVALEPTGTSMRRWAHALSEEAHRDSRVAELDTWRKVLQTPDPVLGKRA
                     YDSAVDVAATVQRISVTVPTQVTETLLTTLPEVFNGGANDGLLAGLALALIEWRRRAGI
                     DSTSALLQLEGHGREEAVIPGADLSRTVGWFTAAFPISLDLS"
     CDS_motif       3382..3432
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34315_0009"
                     /evalue="1.20E-02"
                     /label="Cy2"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="1143"
                     /protein_start="1126"
                     /score="8.5"
                     /tool="antismash"
                     /translation="VVDHHDMFRSRLISDGR"
     CDS_motif       3640..3705
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34315_0010"
                     /evalue="5.10E-11"
                     /label="NRPS-E2"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="1234"
                     /protein_start="1212"
                     /score="34.7"
                     /tool="antismash"
                     /translation="LIIAAHHLIVDGVSWRIIVPDL"
     CDS_motif       4162..4212
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34315_0011"
                     /evalue="1.40E-07"
                     /label="NRPS-E5"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="1403"
                     /protein_start="1386"
                     /score="23.6"
                     /tool="antismash"
                     /translation="DLSRTVGWFTAAFPISL"
     aSDomain        4261..4749
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PXH69_RS34315_TIGR01720.1"
                     /evalue="9.10E-37"
                     /label="PXH69_RS34315_TIGR01720.1"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="1582"
                     /protein_start="1419"
                     /score="118.2"
                     /tool="antismash"
                     /translation="AGRAIKAVKEQLLAIPDKGVGYGLLRYLNEDTRAVLSRFAGGQVS
                     FNYLGRVVAEDLPAGVEGLGWLPAGDFANVSAPEDVDMPANKVVDINAIVNDGADGAVL
                     EASFAYPVGAIDGESVETFAQIWVEALTALAEHSRSVGAGGLTPSDVPLVSVSQRDIDG
                     "
     CDS_motif       4282..4344
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34315_0012"
                     /evalue="6.00E-11"
                     /label="NRPS-E6"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="1447"
                     /protein_start="1426"
                     /score="34.4"
                     /tool="antismash"
                     /translation="VKEQLLAIPDKGVGYGLLRYL"
     aSDomain        4777..5670
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PXH69_RS34315_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.90E-112"
                     /label="PXH69_RS34315_Condensation_DCL.1"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="1889"
                     /protein_start="1591"
                     /score="367.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIILDG"
                     /tool="antismash"
                     /translation="DIWPLAPLQSGLLFHAMLAESSVDLYSVQMILTLSGKVDADRLRT
                     AAQGIIDRYANLRTAFTADDDGTPVQIVLEDVPVPWRNIDLSDIAAVDREAALNEVLTA
                     DQATHFDMASPPLIRFTFVTMAEGDYRLVVANHHIILDGWSVPLLLQNLLALYATRGDD
                     SVLPRVRSYRNYLAWLVDQDRDRSLTAWADVLSGVEEPTLLAQVTGGQEFTALSQKLNV
                     SMSSETTAALTALAARLGVTANTIVQSAWAVLLGALTGTDDVVFGATVSGRPPALTGVE
                     SMVGLFINTLPVRVRLD"
     CDS_motif       4786..4821
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34315_0013"
                     /evalue="4.80E-04"
                     /label="C1_dual_004-017"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="1606"
                     /protein_start="1594"
                     /score="13.0"
                     /tool="antismash"
                     /translation="PLAPLQSGLLFH"
     CDS_motif       4846..4959
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34315_0014"
                     /evalue="9.00E-14"
                     /label="C2_DCL_024-062"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="1652"
                     /protein_start="1614"
                     /score="43.7"
                     /tool="antismash"
                     /translation="DLYSVQMILTLSGKVDADRLRTAAQGIIDRYANLRTAF"
     CDS_motif       5182..5247
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34315_0015"
                     /evalue="7.50E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="1748"
                     /protein_start="1726"
                     /score="34.4"
                     /tool="antismash"
                     /translation="NHHIILDGWSVPLLLQNLLALY"
     CDS_motif       5563..5658
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34315_0016"
                     /evalue="6.20E-21"
                     /label="C5_DCL_263-294"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="1885"
                     /protein_start="1853"
                     /score="66.8"
                     /tool="antismash"
                     /translation="DVVFGATVSGRPPALTGVESMVGLFINTLPVR"
     CDS_motif       5713..5820
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34315_0017"
                     /evalue="9.70E-16"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="PXH69_RS34315"
                     /protein_end="1939"
                     /protein_start="1903"
                     /score="50.2"
                     /tool="antismash"
                     /translation="EQARMLDHHYLGLTDVQKAADVGTLFDTLVVFESYP"
ORIGIN
        1 tgcggcgttg actgcgcagg tgcgtccggt tcgggttccg ttgtcgttgg cgcagcagcg
       61 catgtggttc ctcaaccagt tggatacgag ctcggcaggg aacaacgtcc cggttgcgat
      121 aactctcacc ggagaactgg acgtcttggg gctggagcaa gcggtcgccg acgttatcgg
      181 ccgtcacgag gttctgcgca cggtctaccc cgaggtcgac ggcgtcggct accagaagat
      241 cgttgcaccg gctgatgtcg acgtgaacct cgctgcaacc tcggtctcgg attcggagat
      301 cgtttccgag gtaacgaact tcgtagcggc aggcttcgac gtgacggccg aggtgccgtt
      361 gcgcgccaag cttttccaga tcaaggccga cgagcacgtt ctggtattcg tggtgcatca
      421 catctcgacc gacggtttct cgatgggccc gctgacccgc gacgtcatga ccgcctacta
      481 cgcccgaacc aacggccagg ctccgacctg gacgccgttg ccggtgcagt acgccgatta
      541 ctcgttgtgg cagcgtgagg ttctcgggtc cgaggacgat ccgcagtccg tcatcgcgca
      601 acagatcact tactgggcgc aagcactgga cggcgtgccc gaacagttga atcttccggg
      661 ggatcgggct cggccggcgg tattctccgg tcagggagcg acattcgaat tctcgatcgg
      721 tcaggaattg catgagcggc tgatcagcgt gggccgggaa cacaatgcgt cgatgttcat
      781 ggtggtccat gcggctctgg cgtcgcttct cgctcgtctg tcgggaacaa cggacatcaa
      841 catcggtgca ccgatggccg ggcgaggtga atccgaactc gacgatttga tcggaatgtt
      901 cgtcaacacc ctggttttgc gtaccgaggt tgatccgtcg gcggcgttca caacacttct
      961 ggcctcggct cgggaaaccg accttcaggc gttcgcgcac tcggaccttc cgttcgagcg
     1021 gctcgtggaa gtgctggatc ccgttcggtc gagggcacat cacccgctgt tccaggtggc
     1081 attggcattt cagaacctgg ggcagaactc gttggctctg cccggtctga cggcggccga
     1141 gttcgaaatc gacgagaccg tggccaagtt cgacctgcag ctcacgatca gtgaggtatc
     1201 agaagggctg tcggcgacgt tcacgtacgc gacggatctg ttcgacgaat cgaccgtccg
     1261 cggattcgcc gcacgattga tgcgcattct gaacggaatt gcgacggacc ccgcaacttc
     1321 agtgggtgac atcgaaatcc tcgacgcgtc cgagcgtgag gttctgacga gtcaaagggc
     1381 ttcgtcagga gtagcgcagg cgccgttggc cgagattctt gccgacgctg ctgcgcgcta
     1441 cccggacaac gtcgctttgc gctaccccgg cacggcgcag gccgcggccg gtaggtccat
     1501 gacgtatcga gaggtcgacg agtggtcgtc gaagctggcc cgcgttttga tcaaccgtgg
     1561 tctcggggct gaagatcttg tggcggtgtc gattccgaga tccgtcgaat cggtactcgc
     1621 ggtctgggca gtgtcgaaga ccggggcagc ggtcgttccg atcgatccgc actatccggc
     1681 agaccgtatc gcgcacatgc tcagcgactc gggtgcgaag gttggcctga ccctcgacgt
     1741 cgaacgtccg aatctcgccg acgacgtcga gtggttggtc gtggacggac cgctcggcga
     1801 acagatgatc gccggagtgt ccggagcgcc aatagatgcc gaggaacgtg tccgtccact
     1861 gacgactgct catccggctt gggtcatcta cacctccggc acgacaggac tgccgaaggg
     1921 cgttgtcgcg accaacgcgg gactggcgag cttcagtgtc acgcaggccg cgcactacct
     1981 cgtgaagccc acctcgcgga cattgcactt cgcgtcaccg agtttcgacg cgtcgatgct
     2041 cgagttgttc ctcgcggtgg ccaccggcgc gacgatggtc atcgtcccgc ctggcgtgta
     2101 cggcggcgac gaactggctg aggtgttccg tagcgaacga gtcacgcatg cgttcatcac
     2161 acccgctgcc ctggcgtcga tggacccgag cggcctggac gacctgacgg tggtaggcgt
     2221 gggtggcgaa gcgtattcgc cggaactgat cagcaagtgg acgacagggg acggatcggc
     2281 cgcgtcggct tcggctccca ggacattcct gaatgtctac ggcccgaccg agacgacgat
     2341 cgtgacgaac gtcagcgttc cgcttctgcc cggtgaccga atggacatcg gcgccacgat
     2401 cggtgacatg gccgcattcg tcctggacac acgactcaat ccagttccac tgggagtctc
     2461 gggcgagctg tatctgtccg gtcctcaggt gacccgcggc tatcatcgtc gtccaggctt
     2521 gagtgccgat cgattcgtgg caaacccgca cggtaatccg ggcgagcgaa tgtaccgaac
     2581 cggtgacgtg gtgcgctggg tcgctggaac ggcaccctcc acctacgccg tggaatacgt
     2641 gggccgcaac gatttccagg tcaagattcg cggtttccgt atcgaactgg gcgaaatcga
     2701 tgcatcgctg acggcacacc ccgaggtcga gttcgctgcg acgatgggta cgaccctgcc
     2761 gtcgggtgcc ccggcgctgg tgtcgtacgt gttcaccgga aagcacgctt cggtcacttc
     2821 ggcggaattg atcgaatttg tctccagaac ccttccggcc catatggttc cggcttcggt
     2881 tatggtctcc tcggacatgc cgctcagtcc ggcaggcaag ctggaccgaa aagcgctccc
     2941 agcaccggtt ttcgagacca aggaattccg cgccccggtc accgagatgg aacaaatcct
     3001 gagcgagatc ttcgcggacg ttctcggcct ggatcgcatc ggcaccgacg actcgttctt
     3061 cgctcagggc ggcgactcga tcatgtccat ccaactcgtc tctcgtgcga aggcacgtgg
     3121 ggtcgtattc gcacccagtg acgtcttcga gagcaagact gtcgcggcgt tggccgaagt
     3181 ggcgaagtat gccgccgacg tcgaggccgc ggtggtgctc gaggagttgc cgggcggtgg
     3241 agtcggctgg atgccgttga cgccgatcga acgattcatg gtcgagcgcg gtggcagcta
     3301 caaccgattc acgcagacga tgactctcga gcttccactc ggagtgcatc gaaccgacat
     3361 cgtgcgaaca ctcgccgcag tcgtcgacca ccacgacatg ttccgctcgc ggctgatctc
     3421 cgacggtcgc ggatggggga tgtcggtctc cgagcccgga accgtggacg tcgaggatct
     3481 gctcagccgc gtcgatgtcg acgcggctgc ggacgagtcg acaattgttc tcacggcttc
     3541 caagggcctc gacgaggctc tcggccggtt gaagccggcg gacggcgtaa tggttcagtt
     3601 cgtgtgggtc gacttcggtc ccactcgcac cgggcgcttg atcatcgctg cacatcacct
     3661 gatcgtcgac ggggtctcct ggcgaatcat cgttccggat ctggtgtcgg ctgcggctca
     3721 gatggccggg gcgagcggag cgacggggga tgtagccgga acgacggggg atgttgctct
     3781 cgagccgacc ggtacgtcga tgcgacgctg ggctcatgct ttgtccgaag aggcccatcg
     3841 ggattcgcgt gtggccgagc tggatacgtg gcggaaggtg ttgcagacac cggacccggt
     3901 gctgggtaag agggcgtacg actctgccgt cgacgttgcg gcaacggttc agcggataag
     3961 cgtgacggtc cccactcagg tgacggagac tctgttgacc acgctgccgg aggttttcaa
     4021 cggcggcgcc aacgacggcc tgctcgctgg actggcactc gcgctgatcg agtggcgtcg
     4081 ccgagccgga atcgactcga catctgcctt gctgcaactc gagggccatg gtcgcgaaga
     4141 agccgtgatt cctggcgcgg atctgtcaag gaccgttggt tggttcaccg ctgccttccc
     4201 gatcagtctc gatctttccg aggtagatct gggtgacgct ttcgccggag gtgattcggc
     4261 gggacgcgcg atcaaagcag tgaaggaaca gcttctggcg atcccggaca agggcgtcgg
     4321 gtacggactg ctgcgctacc tgaacgaaga cacgcgcgca gtgctttctc gcttcgcagg
     4381 gggacaggtc agcttcaact acctgggacg agttgtcgcc gaggatcttc cggcaggcgt
     4441 cgagggactc gggtggctgc cggccggcga tttcgccaac gtgtcggcac ccgaagacgt
     4501 cgacatgccc gcaaacaagg tcgtcgacat caatgcgatc gtcaacgacg gcgcagacgg
     4561 tgctgttctg gaggcctctt tcgcataccc cgtcggtgcc atcgacggcg agagtgtcga
     4621 gacatttgca cagatttggg tcgaagcact gactgccctg gcggagcatt ctcgctccgt
     4681 cggagccggt ggactcacac cgtccgacgt gccgcttgtc tccgtgagcc aacgagatat
     4741 cgacggcttc gagaatcgat tcggtacggt gaccgacatc tggcccctgg caccgctgca
     4801 gtccggtttg ctcttccacg cgatgttggc agaatccagc gtcgacctct actcggtgca
     4861 gatgattctc actctgtccg ggaaggtgga tgccgaccga ttgcgcactg cagcacaggg
     4921 aatcatcgac cgttatgcga acctgcgaac ggcattcacg gccgacgacg acggaacgcc
     4981 ggtccagata gtcctcgaag acgttccagt cccgtggcgg aacatcgatc tcagcgatat
     5041 tgcggccgtc gaccgtgagg cagctctgaa cgaagttttg acggctgacc aggcgacaca
     5101 cttcgacatg gcgtcaccgc cgttgattcg gttcaccttc gtcaccatgg cggaggggga
     5161 ctatcgcttg gtggtggcga atcaccacat tattctcgac ggttggtcgg tgccactgct
     5221 cttgcagaac ctgttggcgc tgtacgcgac gcgtggtgac gactcggttc ttccgcgtgt
     5281 gcgtagctat cgcaattacc tggcgtggct tgtcgatcag gatcgtgatc gatcactcac
     5341 agcctgggcg gatgtgcttt ccggcgtcga agagccgacg ctgcttgctc aggtcacagg
     5401 cggacaggaa ttcaccgcgc tgtcacagaa gctgaacgtg tcgatgtcgt cggagacaac
     5461 cgcggcgctc accgctctgg ccgcacgact cggggtcacc gccaacacga tcgtgcagag
     5521 cgcgtgggcg gtcctgctcg gtgcgttgac cggaaccgac gacgttgtct tcggtgcaac
     5581 agtgtccggc cggccaccgg cgctcaccgg cgtcgaatcg atggtcgggt tgttcatcaa
     5641 caccctcccc gtgcgggtgc gcctcgacgc cgcggagtcc gtcggagaat tggttgccag
     5701 ggtccagatc gagcaggcga gaatgcttga tcatcactat ctcggtttga ccgatgtcca
     5761 gaaagcagcg gacgtcggaa cactgttcga cacgttggtt gtattcgagt cgtacccggt
     5821 cgaccgtgag ggcctcgccg cacaggcgga tgttctcgac ggaatgatga tcgacgacat
     5881 tgcctcggac gattccacga actacccgtt gaccctgctg atcgcactcg acgagcagtt
     5941 gcacttgacg ctgcggtacc taccggactt cttcgatgcc gactacgcaa ctgcgttgct
     6001 ggacagagtt cttcgactgc tctcctccgt agccaccgat ccttcggtgc gtgttggtga
     6061 cgttgatatt ttggattctg ttgagcgttc gttggtgctc gaggggtgga atgacacggc
     6121 tcgtgaggtt gcgggtgtgt cggt
//