LOCUS       NZ_JARDXE010000046      7962 bp    DNA     linear   CON 01-APR-2024
DEFINITION  Rhodococcus qingshengii strain HQ HQ1_scaffold46, whole genome
            shotgun sequence.
ACCESSION   NZ_JARDXE010000046
VERSION     NZ_JARDXE010000046.1
KEYWORDS    WGS; RefSeq.
SOURCE      Rhodococcus qingshengii
  ORGANISM  Rhodococcus qingshengii
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Rhodococcus; Rhodococcus erythropolis group.
REFERENCE   1  (bases 1 to 7962)
  AUTHORS   Hu,J. and Xu,J.
  TITLE     A novel hydrolase synthesized by Rhodococcus erythropolis HQ is
            responsible for the detoxification of Zearalenone
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7962)
  AUTHORS   Hu,J. and Xu,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) Grain and Oil Risk Assessment Laboratory,
            Jiangsu Academy of Agricultural Sciences, No. 50, Zhongling Street,
            nanjing 210014, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2022
            Assembly Method                   :: ABySS v. 2.1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: GCA_002079265.1
            Genome Coverage                   :: 470.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_029076895.1-RS_2024_04_01
            Annotation Date                   :: 04/01/2024 06:35:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,927
            CDSs (total)                      :: 6,855
            Genes (coding)                    :: 6,768
            CDSs (with protein)               :: 6,768
            Genes (RNA)                       :: 72
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 33 of 87
            Pseudo Genes (incomplete)         :: 63 of 87
            Pseudo Genes (internal stop)      :: 12 of 87
            Pseudo Genes (multiple problems)  :: 18 of 87
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:34:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 7962
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JARDXE010000046.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..7962
                     /collection_date="2022-01"
                     /country="China: Anhui, Suzhou"
                     /db_xref="taxon:334542"
                     /isolation_source="Corn field soil"
                     /mol_type="genomic DNA"
                     /organism="Rhodococcus qingshengii"
                     /strain="HQ"
                     /submitter_seqid="HQ1_scaffold46"
     gene            <1..>7962
                     /locus_tag="PXH69_RS34310"
                     /old_locus_tag="PXH69_34325"
     region          1..7962
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..7962
                     /SMILES="NC([*])C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..7962
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2:>7962](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..>7962
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     CDS             3..>7962
                     /NRPS_PKS="Domain: PCP (1-58). E-value: 1.5e-17. Score:
                     55.5. Matches aSDomain: nrpspksdomains_PXH69_RS34310_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (74-375). E-value:
                     7.5e-113. Score: 368.4. Matches aSDomain:
                     nrpspksdomains_PXH69_RS34310_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (550-939). E-value: 1.2e-82.
                     Score: 269.6. Matches aSDomain:
                     nrpspksdomains_PXH69_RS34310_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1045-1113). E-value: 1.2e-22.
                     Score: 71.9. Matches aSDomain:
                     nrpspksdomains_PXH69_RS34310_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (1129-1437). E-value:
                     5.6e-113. Score: 368.8. Matches aSDomain:
                     nrpspksdomains_PXH69_RS34310_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (1605-1998). E-value:
                     2.4e-96. Score: 314.8. Matches aSDomain:
                     nrpspksdomains_PXH69_RS34310_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2104-2170). E-value: 4.6e-25.
                     Score: 79.6. Matches aSDomain:
                     nrpspksdomains_PXH69_RS34310_PCP.3"
                     /NRPS_PKS="Domain: Condensation_LCL (2189-2488). E-value:
                     4e-114. Score: 372.6. Matches aSDomain:
                     nrpspksdomains_PXH69_RS34310_Condensation_LCL.3"
                     /codon_start=2
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="PXH69_RS34310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_34325"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_275233155.1"
                     /sec_met_domain="PP-binding (E-value: 5.1e-17, bitscore:
                     48.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.2e-109, bitscore:
                     350.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.4e-66, bitscore:
                     209.9, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGVDRVGLDDDFFALGGNSLIATRVAARLGQALDAQVPVRMLFE
                     SSIVHEFAVRLTSAAGSGARAPLVPQPRPEHIPLSLAQQRMWFLSVFDPESAVNNIPMA
                     IRLSGVLDVDALQAAIADLITRHEILRTVYPEIDGVGYQRILPLRDAGVQLLPVDIAEA
                     DLDAAVADFIGTGFDVRSHVPLRAKLLRIADDDFMVVIVVHHIAADGFSMGPMTRDVMI
                     SYEARSRGEKPGWHPLPIQFADYALWQREVLGSEDDPASLISRQVEFWKTRLSGVPDTF
                     DLPMDRPRPAIATNRGRTHAFAIDAMLHVKILDLAAENNVTPFMVVHAAFAVLLSRLSG
                     SSDVVVGVPVAGRGDVELDDLIGMFVNAVVLRTPVHGTDSFSGLLARVKEIDLSSLANS
                     DVPFERLVEVLNPVRSQSHNPIFQVEFAFQNMEKSTLELDRLSASGGEVASGHSPFDLG
                     LAVTELTAPDGTPSGMAGHLTYAVDLFDESTIVSFGRRFVQILEAIVQSSDQSIGDVDV
                     LSEVERASIFADSIAVAALPQATSLLERFRLRRNTSPTAIAVVAGDRVMTYEDLDRHSS
                     ALARELRSNDIRADDVVALAFVRSVEWIVALVATWKIGAAYAPVDPTQPLARIRSLVSD
                     LTAKCIVGMEDWISERNFPVSTIGVGSPIEDLDVDDSHDDWRVLRAPLRLGYVITTSGS
                     TGKPKATCVPISGIENTVDWYEKLLDLRTPSGILVATSPSFDLTQKNIWVALSGGHTIH
                     LSDPQFDPNEILNTISRGAVRVANMSPSVFEAVVEADSSAILSCLESVFLGGEPLRTGR
                     LAGVAASGVKIFNSYGPTEASDVVSFHQADMDEPDVPIGRPIPNTNLFVLDSRLQLVPT
                     NVVGELYVGGVGIGRGYGGRADLTAERFVAHPLVGAGERMYRTGDLVRWNKLGELEYIG
                     RSDFQVKLRGMRIELGEIESAFLSVPGIAHAVVVVRPVPEVGDRLVAYVVGESVSAVDI
                     ESLRAELGTRLPSYMVPSAIVVLDSLPLNASGKIDRKQLPEPGFITNEFRPPVTLVEKA
                     VAEVFVELLGAGRVGLDDDFFDLGGNSLVATRVASRLGRALDAQVPVRAVFEATTVQAL
                     AERIAKLAGEGSRLELSAQVRPDRIPLSLAQQRMWFLNRLDSKSTANNIPIAIRLTGDL
                     DIDALQAAVEDLVGRHESLRTLYPEVDGVGYQHILPAGEAVLDLKPVEVSETEAIRAVS
                     DFVATSFDVTREVPVRARLFELFNESKRSKAEYLLAFVVHHVAGDGFSIGPLTRDLMIS
                     YESRHRGTAPDWTPLAIQYADYAIWQRIVLGSDDDPTSTLARQVAYWRSTLESIPDELQ
                     LPVDRSRPAVATNEGATYRFSIGESAHRHLETLGRVHDASTFMVMHAALAVLLARLSGT
                     SDIVIGTPIAGRGEAELDDLIGMFVNTLVLRTNIDPQMSFAALIDHVRERDLGAFAHSD
                     VPFEALVEVLNPERSQGRHPLFQVALVFQNAGGSVLKLGDLTVTGLDTDSSAAKFDLQL
                     TLIEQFDEIGQPAGIASEFTYATDLFDHETVQTIARRFLRVIDAITEESASVVGNLEVL
                     SADERDQLLNRSGGSAAEIVLLPDLLARTVELSPHAVAIRFEGKSTTYSELDVFSSQLA
                     RVLICRGVGPEDRIAVAIPRSTESIVALWAVAKTGAVYLPVDPKYPADRVKFMLVDSGA
                     ALGLTTDEIIDTLPAEVDWLTIDSGLVSNTRDLTPTIVDADRVRPLRSANTAYMIYTSG
                     STGRPKGVLVTHKGLANFAVEQETRYELDERTRALHFASPSFDASILELLLAVTVGGTL
                     VIAPDSIYGGSELAVLVDEEQVSHAFMTPAALGSMDPAILEGLGVVIAGGEACPPELVA
                     NWAPGRRFFNGYGPTETTIMTNISSPLVSGSKVTIGGPIRGMTSKILDQRLRPVPIGVS
                     GELYLSGIQLARGYHTRPSMTAERFVADPFGPVGQVMYRTGDLARWTDSYEVEYVGRSD
                     FQVKVRGFRIELGEIESALMQHDSVSRAVVLVRRDDNEIDRIVAYVVPTSGWSVEPDRL
                     IEFAAGSLTRYMIPDAVVVVPRLPLTANGKLDRDALPVPSYRVREFRAPTNSVEEAVAS
                     TFADVLGVKRVGVGDDFFDLGGNSLLATQVVSRLGRALDTTVAVRDLFDTPVVERLAAT
                     LISEVGRGEAVALERAERPELIPLSLAQQRMWFLNRFEESSAVDNIPVAIRLAGKLDVI
                     ALQAAVRDLIERHEVLRTVYPEIHGVGYQDIRGAFELDMKPLVLNEQEILGAVASVLST
                     GFDVTKDIPIRAAIFEISEADHVLVFVIHHIAADGFSMGPLTRDVMIAYEARSRGAAPA
                     WNPLEIQYADYALWQRELLGSEGDENSIVTRQLDYWTAHLDGLPDLLQLPFDRERPVVA
                     SNHGASVSVMIDSEIHRSINEVAHRTNTTTFMVVHAALVVLLAQLSSTSDIAIGTPVAG
                     RGERVLDDVIGMFVNTLVLRTQVSLGDTFEDLVAKVRDVDLGAFSNADIPFERLVDVLN
                     PVRTRSRNPLFQVMLSFHNAGQTVFELPGLTLSAVDSEMALSKFDLDVTLSESIDDLGN
                     PAGILTQFTYATDLFDESTVAGFADRFGRILGAVVADQSIVLGDIDILDSVERSLVLEG
                     WNDTAREVAGVSV"
     aSDomain        7..177
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PXH69_RS34310_PCP.1"
                     /evalue="1.50E-17"
                     /label="PXH69_RS34310_PCP.1"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="58"
                     /protein_start="1"
                     /score="55.5"
                     /tool="antismash"
                     /translation="LGVDRVGLDDDFFALGGNSLIATRVAARLGQALDAQVPVRMLFES
                     SIVHEFAVRLTS"
     aSDomain        226..1128
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PXH69_RS34310_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="7.50E-113"
                     /label="PXH69_RS34310_Condensation_LCL.1"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="375"
                     /protein_start="74"
                     /score="368.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAADG"
                     /tool="antismash"
                     /translation="EHIPLSLAQQRMWFLSVFDPESAVNNIPMAIRLSGVLDVDALQAA
                     IADLITRHEILRTVYPEIDGVGYQRILPLRDAGVQLLPVDIAEADLDAAVADFIGTGFD
                     VRSHVPLRAKLLRIADDDFMVVIVVHHIAADGFSMGPMTRDVMISYEARSRGEKPGWHP
                     LPIQFADYALWQREVLGSEDDPASLISRQVEFWKTRLSGVPDTFDLPMDRPRPAIATNR
                     GRTHAFAIDAMLHVKILDLAAENNVTPFMVVHAAFAVLLSRLSGSSDVVVGVPVAGRGD
                     VELDDLIGMFVNAVVLRTPV"
     aSModule        226..3342
                     /complete
                     /domains="nrpspksdomains_PXH69_RS34310_Condensation_LCL.1"
                     /domains="nrpspksdomains_PXH69_RS34310_AMP-binding.1"
                     /domains="nrpspksdomains_PXH69_RS34310_PCP.2"
                     /locus_tags="PXH69_RS34310"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       241..270
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0001"
                     /evalue="1.90E-02"
                     /label="C1_LCL_004-017"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="89"
                     /protein_start="79"
                     /score="7.9"
                     /tool="antismash"
                     /translation="SLAQQRMWFL"
     CDS_motif       295..408
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0002"
                     /evalue="5.80E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="135"
                     /protein_start="97"
                     /score="54.1"
                     /tool="antismash"
                     /translation="VNNIPMAIRLSGVLDVDALQAAIADLITRHEILRTVYP"
     CDS_motif       610..666
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0003"
                     /evalue="5.40E-07"
                     /label="C3_LCL_132-143"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="221"
                     /protein_start="202"
                     /score="22.2"
                     /tool="antismash"
                     /translation="VHHIAADGFSMGPMTRDVM"
     CDS_motif       724..762
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0004"
                     /evalue="6.20E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="253"
                     /protein_start="240"
                     /score="15.6"
                     /tool="antismash"
                     /translation="QFADYALWQREVL"
     CDS_motif       1030..1119
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0005"
                     /evalue="1.90E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="372"
                     /protein_start="342"
                     /score="42.7"
                     /tool="antismash"
                     /translation="DVVVGVPVAGRGDVELDDLIGMFVNAVVLR"
     CDS_motif       1180..1287
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0006"
                     /evalue="9.10E-17"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="428"
                     /protein_start="392"
                     /score="53.4"
                     /tool="antismash"
                     /translation="LSSLANSDVPFERLVEVLNPVRSQSHNPIFQVEFAF"
     aSDomain        1654..2820
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PXH69_RS34310_AMP-binding.1"
                     /evalue="1.20E-82"
                     /label="PXH69_RS34310_AMP-binding.1"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="939"
                     /protein_start="550"
                     /score="269.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="NTSPTAIAVVAGDRVMTYEDLDRHSSALARELRSNDIRADDVVAL
                     AFVRSVEWIVALVATWKIGAAYAPVDPTQPLARIRSLVSDLTAKCIVGMEDWISERNFP
                     VSTIGVGSPIEDLDVDDSHDDWRVLRAPLRLGYVITTSGSTGKPKATCVPISGIENTVD
                     WYEKLLDLRTPSGILVATSPSFDLTQKNIWVALSGGHTIHLSDPQFDPNEILNTISRGA
                     VRVANMSPSVFEAVVEADSSAILSCLESVFLGGEPLRTGRLAGVAASGVKIFNSYGPTE
                     ASDVVSFHQADMDEPDVPIGRPIPNTNLFVLDSRLQLVPTNVVGELYVGGVGIGRGYGG
                     RADLTAERFVAHPLVGAGERMYRTGDLVRWNKLGELEYIGRSDFQVKLR"
     CDS_motif       1828..1866
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0007"
                     /evalue="2.40E-02"
                     /label="NRPS-A_a2"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="621"
                     /protein_start="608"
                     /score="8.5"
                     /tool="antismash"
                     /translation="ATWKIGAAYAPVD"
     CDS_motif       2062..2112
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0008"
                     /evalue="2.90E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="703"
                     /protein_start="686"
                     /score="16.9"
                     /tool="antismash"
                     /translation="YVITTSGSTGKPKATCV"
     CDS_motif       2215..2238
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0009"
                     /evalue="2.00E+01"
                     /label="C1_starter_004-017"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="745"
                     /protein_start="737"
                     /score="-0.6"
                     /tool="antismash"
                     /translation="TQKNIWVA"
     CDS_motif       2479..2502
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0010"
                     /evalue="9.90E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="833"
                     /protein_start="825"
                     /score="3.1"
                     /tool="antismash"
                     /translation="SYGPTEAS"
     CDS_motif       2611..2700
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0011"
                     /evalue="2.80E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="899"
                     /protein_start="869"
                     /score="38.8"
                     /tool="antismash"
                     /translation="PTNVVGELYVGGVGIGRGYGGRADLTAERF"
     CDS_motif       2785..2850
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0012"
                     /evalue="1.00E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="949"
                     /protein_start="927"
                     /score="33.7"
                     /tool="antismash"
                     /translation="YIGRSDFQVKLRGMRIELGEIE"
     CDS_motif       3064..3090
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0013"
                     /evalue="3.30E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="1029"
                     /protein_start="1020"
                     /score="4.3"
                     /tool="antismash"
                     /translation="GKIDRKQLP"
     aSDomain        3139..3342
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PXH69_RS34310_PCP.2"
                     /evalue="1.20E-22"
                     /label="PXH69_RS34310_PCP.2"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="1113"
                     /protein_start="1045"
                     /score="71.9"
                     /tool="antismash"
                     /translation="EKAVAEVFVELLGAGRVGLDDDFFDLGGNSLVATRVASRLGRALD
                     AQVPVRAVFEATTVQALAERIAK"
     aSDomain        3391..4314
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PXH69_RS34310_Condensation_LCL.2
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.60E-113"
                     /label="PXH69_RS34310_Condensation_LCL.2"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="1437"
                     /protein_start="1129"
                     /score="368.8"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHVAGDG"
                     /tool="antismash"
                     /translation="DRIPLSLAQQRMWFLNRLDSKSTANNIPIAIRLTGDLDIDALQAA
                     VEDLVGRHESLRTLYPEVDGVGYQHILPAGEAVLDLKPVEVSETEAIRAVSDFVATSFD
                     VTREVPVRARLFELFNESKRSKAEYLLAFVVHHVAGDGFSIGPLTRDLMISYESRHRGT
                     APDWTPLAIQYADYAIWQRIVLGSDDDPTSTLARQVAYWRSTLESIPDELQLPVDRSRP
                     AVATNEGATYRFSIGESAHRHLETLGRVHDASTFMVMHAALAVLLARLSGTSDIVIGTP
                     IAGRGEAELDDLIGMFVNTLVLRTNID"
     aSModule        3391..6513
                     /complete
                     /domains="nrpspksdomains_PXH69_RS34310_Condensation_LCL.2"
                     /domains="nrpspksdomains_PXH69_RS34310_AMP-binding.2"
                     /domains="nrpspksdomains_PXH69_RS34310_PCP.3"
                     /locus_tags="PXH69_RS34310"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3406..3438
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0014"
                     /evalue="1.20E-02"
                     /label="C1_LCL_004-017"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="1145"
                     /protein_start="1134"
                     /score="8.4"
                     /tool="antismash"
                     /translation="SLAQQRMWFLN"
     CDS_motif       3457..3570
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0015"
                     /evalue="6.80E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="1189"
                     /protein_start="1151"
                     /score="53.9"
                     /tool="antismash"
                     /translation="TANNIPIAIRLTGDLDIDALQAAVEDLVGRHESLRTLY"
     CDS_motif       3793..3849
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0016"
                     /evalue="1.20E-05"
                     /label="C3_LCL_132-143"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="1282"
                     /protein_start="1263"
                     /score="18.0"
                     /tool="antismash"
                     /translation="VHHVAGDGFSIGPLTRDLM"
     CDS_motif       3907..3936
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0017"
                     /evalue="2.30E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="1311"
                     /protein_start="1301"
                     /score="16.9"
                     /tool="antismash"
                     /translation="QYADYAIWQR"
     CDS_motif       4213..4302
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0018"
                     /evalue="8.20E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="1433"
                     /protein_start="1403"
                     /score="53.5"
                     /tool="antismash"
                     /translation="DIVIGTPIAGRGEAELDDLIGMFVNTLVLR"
     CDS_motif       4351..4470
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0019"
                     /evalue="6.40E-20"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="1489"
                     /protein_start="1449"
                     /score="63.6"
                     /tool="antismash"
                     /translation="RERDLGAFAHSDVPFEALVEVLNPERSQGRHPLFQVALVF"
     aSDomain        4819..5997
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PXH69_RS34310_AMP-binding.2"
                     /evalue="2.40E-96"
                     /label="PXH69_RS34310_AMP-binding.2"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="1998"
                     /protein_start="1605"
                     /score="314.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ARTVELSPHAVAIRFEGKSTTYSELDVFSSQLARVLICRGVGPED
                     RIAVAIPRSTESIVALWAVAKTGAVYLPVDPKYPADRVKFMLVDSGAALGLTTDEIIDT
                     LPAEVDWLTIDSGLVSNTRDLTPTIVDADRVRPLRSANTAYMIYTSGSTGRPKGVLVTH
                     KGLANFAVEQETRYELDERTRALHFASPSFDASILELLLAVTVGGTLVIAPDSIYGGSE
                     LAVLVDEEQVSHAFMTPAALGSMDPAILEGLGVVIAGGEACPPELVANWAPGRRFFNGY
                     GPTETTIMTNISSPLVSGSKVTIGGPIRGMTSKILDQRLRPVPIGVSGELYLSGIQLAR
                     GYHTRPSMTAERFVADPFGPVGQVMYRTGDLARWTDSYEVEYVGRSDFQVKVR"
     CDS_motif       5002..5043
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0020"
                     /evalue="3.60E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="1680"
                     /protein_start="1666"
                     /score="11.0"
                     /tool="antismash"
                     /translation="WAVAKTGAVYLPVD"
     CDS_motif       5248..5307
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0021"
                     /evalue="5.30E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="1768"
                     /protein_start="1748"
                     /score="31.2"
                     /tool="antismash"
                     /translation="AYMIYTSGSTGRPKGVLVTH"
     CDS_motif       5659..5688
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0022"
                     /evalue="4.70E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="1895"
                     /protein_start="1885"
                     /score="6.9"
                     /tool="antismash"
                     /translation="YGPTETTIMT"
     CDS_motif       5788..5877
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0023"
                     /evalue="2.20E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="1958"
                     /protein_start="1928"
                     /score="45.5"
                     /tool="antismash"
                     /translation="PIGVSGELYLSGIQLARGYHTRPSMTAERF"
     CDS_motif       5962..6027
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0024"
                     /evalue="8.70E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="2008"
                     /protein_start="1986"
                     /score="37.0"
                     /tool="antismash"
                     /translation="YVGRSDFQVKVRGFRIELGEIE"
     CDS_motif       6109..6141
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0025"
                     /evalue="1.10E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="2046"
                     /protein_start="2035"
                     /score="-0.1"
                     /tool="antismash"
                     /translation="AYVVPTSGWSV"
     CDS_motif       6241..6267
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0026"
                     /evalue="9.00E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="2088"
                     /protein_start="2079"
                     /score="3.1"
                     /tool="antismash"
                     /translation="GKLDRDALP"
     aSDomain        6316..6513
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PXH69_RS34310_PCP.3"
                     /evalue="4.60E-25"
                     /label="PXH69_RS34310_PCP.3"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="2170"
                     /protein_start="2104"
                     /score="79.6"
                     /tool="antismash"
                     /translation="EEAVASTFADVLGVKRVGVGDDFFDLGGNSLLATQVVSRLGRALD
                     TTVAVRDLFDTPVVERLAATL"
     aSDomain        6571..7467
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PXH69_RS34310_Condensation_LCL.3
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="4.00E-114"
                     /label="PXH69_RS34310_Condensation_LCL.3"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="2488"
                     /protein_start="2189"
                     /score="372.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIAADG"
                     /tool="antismash"
                     /translation="LIPLSLAQQRMWFLNRFEESSAVDNIPVAIRLAGKLDVIALQAAV
                     RDLIERHEVLRTVYPEIHGVGYQDIRGAFELDMKPLVLNEQEILGAVASVLSTGFDVTK
                     DIPIRAAIFEISEADHVLVFVIHHIAADGFSMGPLTRDVMIAYEARSRGAAPAWNPLEI
                     QYADYALWQRELLGSEGDENSIVTRQLDYWTAHLDGLPDLLQLPFDRERPVVASNHGAS
                     VSVMIDSEIHRSINEVAHRTNTTTFMVVHAALVVLLAQLSSTSDIAIGTPVAGRGERVL
                     DDVIGMFVNTLVLRTQVS"
     CDS_motif       6583..6615
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0027"
                     /evalue="1.20E-02"
                     /label="C1_LCL_004-017"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="2204"
                     /protein_start="2193"
                     /score="8.4"
                     /tool="antismash"
                     /translation="SLAQQRMWFLN"
     CDS_motif       6643..6750
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0028"
                     /evalue="2.50E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="2249"
                     /protein_start="2213"
                     /score="48.8"
                     /tool="antismash"
                     /translation="NIPVAIRLAGKLDVIALQAAVRDLIERHEVLRTVYP"
     CDS_motif       6946..7011
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0029"
                     /evalue="8.60E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="2336"
                     /protein_start="2314"
                     /score="24.8"
                     /tool="antismash"
                     /translation="IHHIAADGFSMGPLTRDVMIAY"
     CDS_motif       7060..7098
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0030"
                     /evalue="5.20E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="2365"
                     /protein_start="2352"
                     /score="18.9"
                     /tool="antismash"
                     /translation="QYADYALWQRELL"
     CDS_motif       7366..7455
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0031"
                     /evalue="1.20E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="2484"
                     /protein_start="2454"
                     /score="43.3"
                     /tool="antismash"
                     /translation="DIAIGTPVAGRGERVLDDVIGMFVNTLVLR"
     CDS_motif       7504..7623
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PXH69_RS34310_0032"
                     /evalue="3.90E-19"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="PXH69_RS34310"
                     /protein_end="2540"
                     /protein_start="2500"
                     /score="61.0"
                     /tool="antismash"
                     /translation="RDVDLGAFSNADIPFERLVDVLNPVRTRSRNPLFQVMLSF"
ORIGIN
        1 tctgctgggt gtcgatcgag tgggtctcga tgacgatttc ttcgcactcg gtggtaattc
       61 gctgatcgcg acacgagtgg cggctcgctt gggtcaggcg ctcgatgcgc aggttccggt
      121 gcgaatgctg ttcgagtcgt cgatcgttca tgaatttgcc gttcgtctca cgtcggcagc
      181 aggctcgggt gcgcgggcgc ctctcgtgcc tcaacctcgc ccggaacaca ttcctttgtc
      241 attggcacag cagcggatgt ggttcctcag cgttttcgat ccggagtctg ccgtaaacaa
      301 catccccatg gcgatccggt tgtcaggtgt actcgatgtc gatgcgttgc aagccgcgat
      361 cgcggatttg attacgcgtc atgaaatctt gcgaaccgtg tatcctgaaa tcgatggagt
      421 cggataccag cgaattcttc cgctccgcga tgcaggcgtc caactattgc ctgtggatat
      481 tgctgaagca gatctcgatg cggccgtagc ggacttcatc ggtacgggct tcgacgtgag
      541 atctcatgtt ccgctgcgtg caaagctgct gcgaatcgcc gatgacgatt tcatggtggt
      601 gatcgtggtg catcacattg cagcggacgg tttttcgatg ggccccatga cccgggacgt
      661 aatgatctcg tacgaggcgc ggagccgtgg tgaaaagccg gggtggcacc cgttacctat
      721 ccaatttgcc gactacgctc tctggcaacg ggaagtcttg gggtctgagg acgatcccgc
      781 cagtctgatc tcgcgccagg tcgaattttg gaagactcgt ctcagtggcg taccggacac
      841 gttcgatctc ccgatggatc ggccccgccc agcaattgct accaatcgag ggcggactca
      901 cgcattcgcg atcgatgcaa tgttgcacgt caagatcctg gatctcgcgg cggagaacaa
      961 tgtgactcca ttcatggttg tgcatgcggc atttgccgtt ctgttgtcgc gtttgagtgg
     1021 ctcttcagat gtggtggtcg gtgttccggt ggcgggacgt ggggacgtcg aattggacga
     1081 cctgatcggg atgttcgtca atgcggttgt tctgcgtact cctgtccacg gcactgattc
     1141 gttcagtggg cttttggcgc gagtgaaaga aatcgacctt tcttcgcttg ccaattccga
     1201 tgtgccgttc gaacgtcttg tcgaggtgct caaccctgtt cgctcacaat cacacaaccc
     1261 gatcttccaa gtcgagttcg cgtttcagaa catggaaaag tcgactctcg aactcgatcg
     1321 cttgtcggcc tccggtggtg aagtggcgtc gggacactct ccgttcgacc ttggactggc
     1381 ggtaaccgaa ctgaccgcgc ctgatgggac tccgtccggg atggctggac atctgacgta
     1441 cgcagtcgac ctgttcgatg aatctacgat cgtctcgttt ggccggcgtt tcgtgcagat
     1501 actcgaggca attgttcagt cgagcgacca atcgatcggt gacgtcgacg ttctcagtga
     1561 agtggaacgt gcgagtatct ttgcggattc gattgcggtt gcggcacttc cccaagctac
     1621 ctccctactg gagaggttcc gtcttcgacg aaacacctca cccacagcga ttgccgtagt
     1681 tgcgggtgat cgggtgatga cgtacgaaga tttggatcga cattcttcgg cgttggcacg
     1741 cgagctgcga tcaaatgata ttcgtgcgga tgatgtagtg gcacttgctt ttgtccgatc
     1801 tgtcgaatgg atcgtggcgt tggtggcgac atggaaaatc ggcgcggcct atgcgccagt
     1861 tgatccgact caacctttgg ctcgtatccg ttcgttggtc tcggatctga ctgctaaatg
     1921 cattgttgga atggaagatt ggatctccga acgaaatttt ccagtttcga cgatcggggt
     1981 ggggtctcca atcgaggatc tcgatgttga tgattcacac gacgactggc gagtgctccg
     2041 tgctccgctg aggctcggat acgtgatcac gacttcgggg tccactggca agccgaaagc
     2101 aacgtgtgta ccgatatcgg gaatcgagaa cacagtcgat tggtatgaga aacttctgga
     2161 tctgcgaacc ccctccggga tcctggttgc tacatcgcca tctttcgatc tgacgcagaa
     2221 gaatatttgg gtggccctgt ctggtggaca cacgattcac ctgagtgatc cacaattcga
     2281 tccaaacgag atactgaata ctatttctcg tggcgcggta cgtgttgcga acatgtcgcc
     2341 gtccgttttc gaagcggtgg tcgaggccga ttcttcggcg attctgtctt gcctcgaatc
     2401 cgtatttctc ggcggagagc ctctgcgcac cgggcgtctg gcaggagtcg ctgcaagtgg
     2461 cgtaaagatc ttcaacagtt atgggccgac agaagcatca gacgtagtgt ccttccatca
     2521 ggcagatatg gacgaaccag atgttcccat cggtcgacca atcccgaaca ccaatctctt
     2581 cgttctcgat tcgagattgc aacttgtccc aacgaacgtc gtaggcgaat tgtatgtcgg
     2641 tggcgtcggg attggtcgcg gctatggagg ccgcgcagac ctgactgccg agcgctttgt
     2701 cgcgcacccg ttggtcggtg cgggagagcg tatgtatcgc accggagacc tcgtacggtg
     2761 gaacaagctc ggcgagttgg aatacatcgg acgcagtgat tttcaggtca agcttcgcgg
     2821 aatgcgtatc gaactcggcg aaatcgagtc ggcattcttg tccgtgccag gcattgccca
     2881 cgctgtggtc gtcgttcggc ccgtgccaga ggttggtgat cgattggtcg catacgtcgt
     2941 cggtgaatca gtgagtgctg ttgacatcga gagtttgaga gcggaattgg gcacgcgatt
     3001 gccctcttac atggtgccct cggcgatcgt ggtgctcgac tccttgccgc tgaatgcgtc
     3061 aggaaagatc gaccgcaagc agttacccga gcctggattt atcacgaatg agtttcgccc
     3121 cccggtcaca ctggtcgaga aagcagtggc cgaagttttc gtcgaactgt tgggtgcagg
     3181 tcgggtgggt ctcgacgacg acttctttga tttaggagga aattccctcg tcgcgacgcg
     3241 ggtcgcgtcg cggctgggcc gcgctctgga cgcacaggtt cctgttcgtg cagtatttga
     3301 agccacaacg gtccaagcgc tggccgagcg cattgcgaaa cttgcgggtg aaggcagtcg
     3361 tcttgagctt tcagcgcaag tgcgcccgga ccgtatccca ctctcgttgg cgcaacagag
     3421 gatgtggttc ctcaaccgcc ttgattccaa gtcgacagca aataacattc cgatcgcgat
     3481 ccgactgact ggcgatttgg acatcgacgc gttgcaggcg gcagttgaag acctagtcgg
     3541 ccgtcacgaa tcccttcgaa ccctgtaccc ggaagtcgac ggcgtcggtt accaacacat
     3601 tctccccgcg ggcgaagcag tacttgacct caagccggtc gaggtttcgg aaactgaagc
     3661 gatacgtgcg gtgtcagact ttgtggcgac gagcttcgac gtcactcgcg aggttccagt
     3721 tcgtgcgcga ttgttcgaat tgttcaatga atcaaaaagg tcgaaggccg agtatttgct
     3781 ggccttcgtc gtccaccatg ttgccggcga cgggttttcg attggcccgc ttacccgaga
     3841 tctgatgatc agctacgaat cccggcacag gggcacggcg ccagactgga caccgctcgc
     3901 aattcagtac gcggactacg ccatctggca gcgaatcgtt ctcggatcgg atgacgaccc
     3961 gacgtcgaca cttgcacgcc aagtggcgta ctggcgatca acgctcgaat cgattcccga
     4021 tgagctgcaa ctaccagtcg accgttctcg cccggcggtt gcaacaaacg agggcgccac
     4081 ataccgcttc tcaatcggag aatcggcgca tcgacacttg gagaccctcg gacgagtgca
     4141 tgacgcgtcg accttcatgg tcatgcacgc ggctctcgct gtcctgctcg ctagattgtc
     4201 tggaacatcg gacatagtta tcggcactcc catcgctggt cgcggcgaag cagagttaga
     4261 cgatctgatc ggaatgttcg tcaacacgct ggtactccga acgaacatag atccccagat
     4321 gtcgttcgca gcactgatcg atcacgtgcg ggagcgagac ctcggcgcgt tcgctcattc
     4381 ggatgttccc ttcgaagccc tcgtcgaagt gttgaaccct gagcggtcgc aaggtcgtca
     4441 ccctctcttc caggttgccc tggtcttcca gaatgcaggt ggctcagtgt tgaagttggg
     4501 tgacctcacg gttaccggcc tcgatacgga ttcctccgct gcgaaattcg atctgcagtt
     4561 gacgctcatc gaacaattcg acgagattgg acaaccagcg ggaattgcct ctgaattcac
     4621 ctacgcgaca gacttgttcg accatgaaac ggtgcagacg atcgctcgga gattcctccg
     4681 agtaatcgat gccatcacgg aagagtcggc gagcgttgtc ggcaacctcg aagtgctgtc
     4741 ggccgatgaa cgtgatcaac tattgaatcg aagtgggggg tctgcagcgg aaatcgtctt
     4801 gctgccagat cttctggcgc gaacggtcga gttgtctccg cacgctgtag ccatccgttt
     4861 cgagggcaag tcgacaacct actccgaact ggatgtattt tcctcgcagc tagctcgggt
     4921 gttgatatgt cggggtgtcg ggcccgaaga tcgaatcgcg gtggcgatac cgcgatcgac
     4981 agaatcgatt gttgccttgt gggctgtcgc caagactggt gctgtttatc tgcccgttga
     5041 tccgaagtat cctgccgatc gtgtgaagtt catgctcgtc gactcgggtg cagctctcgg
     5101 attgacgacc gacgagatca tcgatactct gcctgccgaa gtcgactggt tgacaattga
     5161 ttccggtttg gtgtcgaaca cgagggatct cacgccgacg attgtcgacg ctgaccgtgt
     5221 tcgaccattg cgaagtgcca ataccgctta catgatctat acctcgggtt cgacaggtcg
     5281 gcccaagggc gtcttggtga cccacaaagg attggccaac ttcgctgttg aacaggaaac
     5341 tcgctacgag ttggacgagc gcacgcgcgc gctgcatttc gcgtcgccga gcttcgacgc
     5401 gtcgattctc gaactgcttt tggccgttac cgttggtggg acgttggtga tcgcaccaga
     5461 ctcgatctac ggtgggtccg aacttgcagt gttggtcgac gaggaacagg tctcgcacgc
     5521 attcatgacc cccgccgcgt tggggtccat ggacccagcg atcctcgaag gtctgggtgt
     5581 ggtcattgcc ggaggagagg cttgccctcc tgagttggtg gcgaattggg ccccaggtcg
     5641 acgattcttc aacgggtacg gacccaccga aaccacgatc atgaccaaca tcagttcacc
     5701 gttggtttca ggatcgaagg tgacaatcgg tggtccgatt cgaggaatga cgtcgaagat
     5761 tctggatcaa cgacttcgcc ctgttccgat tggtgtttcc ggtgagctct acctctcagg
     5821 cattcaactt gcacgcggat atcacactcg cccttcgatg accgcggaac gctttgtcgc
     5881 agatccgttc ggtccggtcg ggcaggtcat gtatcgcacg ggtgatctgg cacgatggac
     5941 cgattcgtac gaggtcgagt atgtcggacg aagtgacttc caggtcaagg tccgtggctt
     6001 ccgcatcgaa cttggtgaaa tcgaatctgc tctgatgcaa catgattcgg tcagtcgggc
     6061 agtcgttctt gtgcggcgag acgacaatga aatcgacaga attgtcgctt atgtggtccc
     6121 aacctccgga tggtcggtcg aacctgaccg cctgatcgag tttgcggcgg gttcgctgac
     6181 tcgttacatg attcccgacg ccgttgtcgt tgtcccgagg cttcccctga ctgcgaatgg
     6241 aaagcttgat cgtgatgcgc ttccggtgcc gtcataccgc gttcgagagt ttcgtgcacc
     6301 gaccaactcg gtcgaagaag cggttgcctc aaccttcgcg gatgtgctgg gcgtgaaacg
     6361 cgtcggagtg ggtgatgatt tcttcgacct cggtggaaac tcccttcttg caacacaagt
     6421 cgtctcccga ttggggcgcg cgctcgacac caccgtggcc gtgcgcgact tgtttgacac
     6481 gcctgtggtc gagcgcctgg ctgcgacact gatcagcgag gtcggccgag gcgaagcagt
     6541 tgcgctcgag agagccgagc ggcccgagtt gatcccgctc tcacttgctc aacagcgcat
     6601 gtggttcctc aatcgattcg aagaatcgtc agccgtcgac aacattccgg tcgcaatcag
     6661 acttgccggc aagctcgatg tcattgcgct acaagcggcc gttcgggatc tgatcgaacg
     6721 ccacgaagtg ctgcgcaccg tctatcccga gatccacggg gtcggttatc aggatattcg
     6781 cggtgcattc gagctggata tgaagccctt ggtactgaac gaacaggaga tactcggagc
     6841 agttgcttca gttctttcga ccggattcga tgtaaccaag gatattccga tccgggccgc
     6901 gatcttcgag atctccgagg cggatcacgt tttggtgttt gtcattcacc acattgcagc
     6961 cgatggcttc tcaatgggac cattgacccg cgacgtgatg attgcctatg aagctcgttc
     7021 acggggggca gctccggcgt ggaacccgct ggaaattcag tacgcggatt atgcgttgtg
     7081 gcagcgagag cttctaggct ccgagggcga tgagaattcg atcgtgaccc gccagctcga
     7141 ctactggact gcacacctcg atggactgcc tgatcttctg caattgccat tcgatcgtga
     7201 acgtccggta gtcgcaagca atcacggcgc gagtgtgagt gtcatgatcg acagtgagat
     7261 tcatcggagc atcaacgagg ttgcacatcg cacaaataca acaacgttca tggttgtgca
     7321 tgctgcgctg gtcgtcctac tcgcgcaatt gtcttcgacc agcgacatcg cgatcggtac
     7381 accggtcgcc ggtcgaggcg agcgagttct cgacgatgtt atcggcatgt tcgtgaatac
     7441 cctcgtgctg cgaacacaag tctcactcgg ggatacgttc gaagatcttg ttgccaaggt
     7501 gcgcgacgtc gaccttggag cattttccaa cgccgacata ccgttcgagc gactggtcga
     7561 tgtgctcaat cccgtccgaa cgcgttcgcg gaatccactc tttcaggtga tgctgtcgtt
     7621 ccacaacgcc ggacagacgg tgttcgaact tccggggttg acgctgagtg cggttgattc
     7681 cgagatggcg ttgtcgaagt tcgatctcga tgtgactctg agcgagagta tcgacgatct
     7741 aggtaacccc gctggaatcc ttactcagtt cacgtatgcg acggatttgt tcgacgagtc
     7801 gacggttgct gggttcgcgg acaggttcgg gcggatcctc ggtgctgttg ttgctgatca
     7861 gtcaattgtt ttgggtgaca tagacatttt ggattctgtt gagcgttcgt tggtgctcga
     7921 ggggtggaat gacacggctc gtgaggttgc gggtgtgtcg gt
//
