LOCUS       NZ_JARDXE010000005     25366 bp    DNA     linear   CON 01-APR-2024
DEFINITION  Rhodococcus qingshengii strain HQ HQ1_scaffold5, whole genome
            shotgun sequence.
ACCESSION   NZ_JARDXE010000005
VERSION     NZ_JARDXE010000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Rhodococcus qingshengii
  ORGANISM  Rhodococcus qingshengii
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Rhodococcus; Rhodococcus erythropolis group.
REFERENCE   1  (bases 1 to 356897)
  AUTHORS   Hu,J. and Xu,J.
  TITLE     A novel hydrolase synthesized by Rhodococcus erythropolis HQ is
            responsible for the detoxification of Zearalenone
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 356897)
  AUTHORS   Hu,J. and Xu,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-2023) Grain and Oil Risk Assessment Laboratory,
            Jiangsu Academy of Agricultural Sciences, No. 50, Zhongling Street,
            nanjing 210014, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2022
            Assembly Method                   :: ABySS v. 2.1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: GCA_002079265.1
            Genome Coverage                   :: 470.0x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_029076895.1-RS_2024_04_01
            Annotation Date                   :: 04/01/2024 06:35:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,927
            CDSs (total)                      :: 6,855
            Genes (coding)                    :: 6,768
            CDSs (with protein)               :: 6,768
            Genes (RNA)                       :: 72
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 33 of 87
            Pseudo Genes (incomplete)         :: 63 of 87
            Pseudo Genes (internal stop)      :: 12 of 87
            Pseudo Genes (multiple problems)  :: 18 of 87
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:34:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 294752
            Orig. end                         :: 320118
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JARDXE010000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25366
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..25366
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25366
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:15366](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15366
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    465..479
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.69"
                     /tool="antismash"
     gene            complement(1473..2117)
                     /locus_tag="PXH69_RS10170"
                     /old_locus_tag="PXH69_10165"
     CDS             complement(1473..2117)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748878.1"
                     /locus_tag="PXH69_RS10170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10165"
                     /product="hypothetical protein"
                     /protein_id="WP_003941715.1"
                     /transl_table=11
                     /translation="MSRQGKSGAAQRAYDKRTARAAGRTGTVAAAGPSISPRAMLKGRV
                     PFVASVIGLLSIGLAVTLLLTTRAAEDSYQLSDARAYNQSLVEQKAALERDFQSRNSAP
                     ELANQASALGMVPAKDPARLVVHPDGSVEVVGTPTPATAGAMPPLDAPTSVPAPTATPP
                     RTTTPVAPGATPSVPNNTRNLAQSEQLVPVIPTTTAPATTTAVPAPPEERR"
     gene            complement(2114..3127)
                     /gene="rsmH"
                     /locus_tag="PXH69_RS10175"
                     /old_locus_tag="PXH69_10170"
     CDS             complement(2114..3127)
                     /EC_number="2.1.1.199"
                     /GO_function="GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="rsmH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748879.1"
                     /locus_tag="PXH69_RS10175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10170"
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="WP_007730079.1"
                     /transl_table=11
                     /translation="MVDHEVNEPSDADGFAHVPVLLHRADDLLGPAITAVGDGGAGAYM
                     IDATLGLGGHSEFFLGKYPGLHLIGLDRDTNALRIASERLAPFADRTTFVHTTYDGIED
                     ALEQAGLPSTESVHAILFDLGVSSMQLDEADRGFAYSIDAPLDMRMDQTVGLTAAEVLN
                     TYSHGDLARILSTYGEERFAGKIASEILRQREREPFTTSAALVELLYRTIPAATRRTGG
                     HPAKRTFQALRIEVNAELDSLRAAVPAGLDALAVGGRVVFMSYQSLEDRVVKAELVPRS
                     KSTSPEGLPVELPGMGPEFRILTRGAERASEQEIEENPRSAPVRLRAAERISRRRA"
     gene            complement(3318..3749)
                     /gene="mraZ"
                     /locus_tag="PXH69_RS10180"
                     /old_locus_tag="PXH69_10175"
     CDS             complement(3318..3749)
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0051302 - regulation of cell division
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mraZ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011560648.1"
                     /locus_tag="PXH69_RS10180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10175"
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="WP_003941779.1"
                     /transl_table=11
                     /translation="MFLGTFTPKLDDKGRLTLPAKFRDELAGGLMITKSQDHSLAIYPR
                     DEFVKLARKAAAAPRNDPAARAYVRALAAGTDEQHADAQGRITLSADHRRYANLSKECV
                     VTGSVDYLEIWDLAAWERYLGDNEEDYSQATGESLSEIV"
     misc_feature    complement(3877..3891)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.88"
                     /tool="antismash"
     gene            complement(4344..4790)
                     /locus_tag="PXH69_RS10185"
                     /old_locus_tag="PXH69_10180"
     CDS             complement(4344..4790)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005247640.1"
                     /locus_tag="PXH69_RS10185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10180"
                     /product="DUF3040 domain-containing protein"
                     /protein_id="WP_003941660.1"
                     /transl_table=11
                     /translation="MPLSEHEQRMLDQIESALYAEDPKFASNVRGGRMRAPSSRRRFQA
                     AALFVLGLVLLIAGVALPLKPGGFPIISLFGFLFMFGAGVLFLWGGGRKSAPAADSASE
                     GGNHPSGPPGRGSAGGSGRGRGRKSGGGFSSRMEDRFKRRFEQD"
     gene            complement(5028..5579)
                     /locus_tag="PXH69_RS10190"
                     /old_locus_tag="PXH69_10185"
     CDS             complement(5028..5579)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748881.1"
                     /locus_tag="PXH69_RS10190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10185"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_256261698.1"
                     /transl_table=11
                     /translation="MSERVKPERVKCQRTLPAELSSPSDAAISRLPMSARRSFGARDVS
                     DRTARVGKSGVAWGLLRKADALLEEAIGAGDPADRFRCAYLAALRGAGAVLAAAPAGAG
                     SKRKRSGNAWVLMDAAAPAFGAWSKFFAGWSSTRAAVETGVSIVITDSDSDAFFAEVGR
                     FLTAVEDFIGQDASEHLRAS"
     misc_feature    5665..5680
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.27"
                     /tool="antismash"
     misc_feature    complement(5666..5679)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.07"
                     /tool="antismash"
     gene            5727..6332
                     /locus_tag="PXH69_RS10195"
                     /old_locus_tag="PXH69_10190"
     CDS             5727..6332
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748882.1"
                     /locus_tag="PXH69_RS10195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10190"
                     /product="N-acetyltransferase"
                     /protein_id="WP_054827542.1"
                     /transl_table=11
                     /translation="MRPVDPQIAWTPHTVDLDRAEFVSRLHEALAVYVTAMDYPRGTEF
                     HRAPMWQEHANRPGWKAVGALAVPQQPSHENLPLVGIAYGYRGSPDQWWHQQVLHGLRR
                     SGRPQSEIDAILSDYFELTELHVHPNGQGHRLGESLLRHLLVDRPERSVLLSTPEVYDE
                     DNRAWRLYRRLGFRDVLRRFRFAGDNRPFAVLGRGLPL"
     gene            6329..7927
                     /locus_tag="PXH69_RS10200"
                     /old_locus_tag="PXH69_10195"
     CDS             6329..7927
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748883.1"
                     /locus_tag="PXH69_RS10200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10195"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_275231725.1"
                     /transl_table=11
                     /translation="MSALLDAVVVGSGHNALASAAYLAREGWSVEVLEKDTVLGGAVST
                     VERFPGYKVDRGSSAHLMIRHSGIIEELGLGAHGLRYIDCDPWAFAPPAPGTDGPGIVF
                     HRDLDATCWSIERACGTKDADSYRRFVAVWSERSRHVMKAFSAPPTGSNLIGAFGGLAT
                     ARGNSELSRQFLAPGDALLDEYFDSEALKAALAWFGAQSGPAMSEPGTAPMVGFAALMH
                     VLPPGRAVGGSGALSAALASRMAVDGATVALGDGVTSIRRNSSHWTATTESGREVHARK
                     VIAGCHILTTLDLLGRGGFDRTTLDHWRRKIRVGPGIGAVLRLATSALPSYRGDATTRE
                     STSGLQLLVSDRAHLRTAHGAALAGELPPRPAVLGMSFSGIDPTIAPAGRHQVTLWSQW
                     QPYRLSGHRDWASVAEAEADRIVGEMEAFAPGFADSVLDRFIQTPRDIESELGMIGGNV
                     MHVEMSLDQMMLWRPLPELSGHRVPGADGLYLTGASTHPGGGVSGASGRSAARIALSDS
                     RRGATRRWMRRSSRS"
     gene            7998..8792
                     /locus_tag="PXH69_RS10205"
                     /old_locus_tag="PXH69_10200"
     CDS             7998..8792
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003941798.1"
                     /locus_tag="PXH69_RS10205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10200"
                     /product="DUF3153 domain-containing protein"
                     /protein_id="WP_073512231.1"
                     /transl_table=11
                     /translation="MTTVQQSTDPAAKPTSRKRFLTVAALALMLVPLLAGCIRVQVSMG
                     VSANDRVTGQVVAAAIPANEADKGPQLTPPSSLEDKIRVQEYKKDGYVGSQAFFSDLSF
                     GDVAQLGSMYAEGSGSFQITLKRSGDTVTLDGKADLKTVPTQGADVQVSIAFPARVGTT
                     NGTRDGDSRVSWTLPAGEVSTMRAEVNYADPSTRSFAGWAGIMAGLALGVAIVVGAMAW
                     MARNRAPIKRAPAAKAPAMKTPVTKSPASKQADTRNPKNTTK"
     misc_feature    complement(8047..8058)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.3"
                     /tool="antismash"
     gene            complement(8841..9830)
                     /locus_tag="PXH69_RS10210"
                     /old_locus_tag="PXH69_10205"
     CDS             complement(8841..9830)
                     /EC_number="1.5.1.20"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0006555 - methionine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003941803.1"
                     /locus_tag="PXH69_RS10210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10205"
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="WP_003941803.1"
                     /transl_table=11
                     /translation="MTFDPVRGRSSEGWATRTPSIVDRIASSTGSRIPFSVEFSPPRDA
                     DAEARLWRAVRTFERLGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSH
                     STEELRAMVGAYADRGISNILVLRGDPPGDPLGEWKKHPEGVEYAEELVRMVRDLGDFH
                     VGVASFPEGHYRAPDLAYDTKYLVSKLRAGAEYSITQMFFDVEDYLRLRDRVSAYDAEQ
                     GAKPIIPEIMPVTSLRSVRRMLELSGSSLPPALERRFDAAAGSGPDENRAAVRELGIDL
                     ATEMGERLIAEGAPCLHFITLNFARATSEVLERLGLTPDTSVGTAQAV"
     gene            10001..11140
                     /locus_tag="PXH69_RS10215"
                     /old_locus_tag="PXH69_10210"
     CDS             10001..11140
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748885.1"
                     /locus_tag="PXH69_RS10215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10210"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_080712766.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 9.1e-50, bitscore:
                     163.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEATLSAGTARVGQSSTNTAPHPTSLELPGLFEAALRDFFASRRE
                     LVSNIGGGYEEAVSTLEAFVLRGGKRVRPSFAWTGWLGAGGDPNGKDADAVIRACAALE
                     LVQACALVHDDIIDASTTRRGFPTVHVEFEDQHRDEEWSGDSAHFGEAVAILLGDLALA
                     WADDMIRESGISPEAAARVSPVWSAMRTEVLGGQFLDISNEARGDETVEAAMRVNRYKT
                     AAYTIERPLHLGAALFGADAELVDAYRTFGTDIGIAFQLRDDLLGVFGDPSVTGKPSGD
                     DLIAGKRTVLFAMALARADAADPAAAELLRNGIGTQLTDTEVDTLRQVITDLGAVTDVE
                     TQIDTLVEAAANALDSSTATAESKARLTDMAIAATKRSY"
     gene            11143..12735
                     /gene="crtI"
                     /locus_tag="PXH69_RS10220"
                     /old_locus_tag="PXH69_10215"
     CDS             11143..12735
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003941668.1"
                     /locus_tag="PXH69_RS10220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10215"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_275231726.1"
                     /sec_met_domain="DAO (E-value: 2.2e-12, bitscore: 41.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHVHRTRTVSSPTDRVVIVGAGLAGLSAGLYLRGAGRDVTILES
                     NSSVGGRVGVYQGNDYSIDNGATVLTMPELVEDALAAVGADPASTNPKFVVHKLDPTYH
                     ARFADGTALDVHADPEDMAAEVSRVCGPEEAQRYRALRRWLNRIFDAEFDRFMDADFDS
                     PLGLVNSRDAVKDLSRLVALGGFGTLGGQVDRKIRDPRLRRIFTFQALYAGVAPSRALA
                     VYGAIAHMDTSLGVYFPEGGMRTIAESMADAFTEAGGILHLGRTVERLEVSGRRVHTVH
                     TRDGERFDCDAAVLTPDMAVTDSLLRPHTRLRPRPVRTSPSAVVIHGTVSSAVADEWPA
                     QRHHMIDFGEAWKRTFAEITARRGRGRLMSDPSLLVTRPAQTDPSLAFSRDGRIREPLS
                     VLAPCPNLDSASLDWSTLGPPYVREIILTLQERGYTGLVEGFEIDHVDTPQTWLEKGMA
                     AGSPFAAAHTFTQTGPFRRKNLARGFDNVVLAGSGTVPGVGVPTVLLSGRLAAERITGT
                     RERASAVGTRASN"
     gene            12834..14411
                     /locus_tag="PXH69_RS10225"
                     /old_locus_tag="PXH69_10220"
     CDS             12834..14411
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003941737.1"
                     /locus_tag="PXH69_RS10225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10220"
                     /product="alpha-(1->6)-mannopyranosyltransferase A"
                     /protein_id="WP_037126786.1"
                     /transl_table=11
                     /translation="MTSSAAATERPWHLRAANFLRTPEGHSALLGFFGAVMITFGGFGA
                     GSVRRQDPLLESMHLSWLRFGHGSILSAAIVWIGVLCMIAAWVRLGRSTLRGDVSLRGL
                     RYVVPVWTFPLLFAVPMFSRDAYSYLAQGALLRNGFDPYAVGPVVNPGILLDNVSNVWT
                     TTTTPYGPVHLLLADAIVRLTGENVIAGTMLLRITMLPGLALMMWAVPHLATKLGGNTS
                     IALWLAVLNPLVLIHLIGGVHNEMLMVGLMAAGIALALERKHLFGIGLIALAVAIKATA
                     GVALPFIVWIWMIHEREDAAAAGQEPASPIRSFVKTAGAGFAVFVAVLGSTSLIAGVGL
                     GWTTALSGSAKIINWLSLPTIVAHIGTMATSWFAGDHFNDILEVSRTISAVVLIAIIAV
                     VWWRYRKTERDAVMGIVIVMVAIVVLSPAALPWYYSWPLAVAAGFAMSPTTLAVLTGLS
                     TWLMLVFQPDGSIGLYTFPHVALAIVAAVIAAMSLQTEDPLRLRGRKHEKPIEMTSAAS
                     APSTSGSA"
     gene            14422..15366
                     /locus_tag="PXH69_RS10230"
                     /old_locus_tag="PXH69_10225"
     CDS             14422..15366
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730072.1"
                     /locus_tag="PXH69_RS10230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10225"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_275231727.1"
                     /sec_met_domain="phytoene_synt (E-value: 6.8e-91, bitscore:
                     298.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.9e-59,
                     bitscore: 194.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALPASYEFCEDVTREHGRTYFLATRLLPEPRRRAVHALYAFAR
                     VVDDVVDEPSGPHERGTVLADVERAAVNALDNPTVTGDVPSTVPLDLTRVLPAFADAVK
                     TFDIPRAYFDAFFESMRMDAPDTAKFRPVYDTMDELSEYMYGSAVVIGLQMLPILGVSV
                     PQQEAVVPASNLGEAFQLTNFIRDVGEDLDRGRLYLPAGEFAAFGVDIEMLEHGRRTGT
                     VDVRVKRALAHFIAVTRGRYRSAESGIPMLDRRVQPSIRTAFVLYGAILDQVERADFRI
                     LHRRVSVPGRTRLRVAAPGLVRSATYAAKNRMR"
     gene            complement(15387..15755)
                     /locus_tag="PXH69_RS10235"
                     /old_locus_tag="PXH69_10230"
     CDS             complement(15387..15755)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007297456.1"
                     /locus_tag="PXH69_RS10235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10230"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_003941747.1"
                     /transl_table=11
                     /translation="MSAIPYCDDVLDSSVSLFQLVDVAKNVGLPVSKVHQLLRDHKIIA
                     VKRHGVLGVPEVFFGEDGQIVKWLPGLLAVLHDGGYTDVEILRWLFLADDSLPGRPVDA
                     LHGDLAREVIRRAQAMAF"
     gene            16059..18122
                     /gene="pknB"
                     /locus_tag="PXH69_RS10240"
                     /old_locus_tag="PXH69_10235"
     CDS             16059..18122
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730071.1"
                     /locus_tag="PXH69_RS10240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10235"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_003941667.1"
                     /sec_met_domain="Pkinase (E-value: 3.4e-50, bitscore:
                     165.0, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGEMLERRYRVDAPIARGGMSTVYRGLDTRLDRPVAIKVMDPQF
                     AGDPAFLTRFEFEARAVARLKHPALVAVYDQGSDRNHVFLVMELVDGGTLRELLRERGP
                     MPPHAVAAVVAPVLDALAVAHRAGLVHRDVKPENILISDTGEVKIADFGLVRAAAAATT
                     TSNSVILGTAAYLSPEQVTSGIADTRSDVYSTGVLMFELLTGTTPFTGDTSLSIAYQRI
                     HDDVPRPGSRIPGVPAQFDRLVAEATHREPAHRFADAGEMAAALRSVSEQLELPSYRVP
                     APRRSAQHQSAQVAPARPQPAPAPPTEVHPNSAARPNPAATTVLASGVAPAVAATTALG
                     TGSPPPGGIQHTRAVTAQTARPATVDGDSDFDDGSDFGDDHPGHDDPHAHFVEARRKSR
                     RATLIWLLVIAVLALALGFGGWWMGSGRYTAVPSIDGLTKDTAVTALQDAGLSPDVQGQ
                     YSDAQPIDTVIGTDPASGSRVTKGSTVALLTSLGRPTVPPIPAGGDVSALGAQLADRTL
                     VAVDGGDTFSSKIPIGGVAALDPAPGTEVAVGSSVKVITSKGSPPVDIPDVKGMSENAA
                     RAALDKVGISVSTTRTTFDDAVEGGSVIGTDPAVGSSVNAGTSVVLLISDSVKVPSLIG
                     RSVSSAREELGRLGLEITVRQLTQNDSSVIISQSVKNDLVAKGTDISVVAIP"
     gene            18150..18578
                     /locus_tag="PXH69_RS10245"
                     /old_locus_tag="PXH69_10240"
     CDS             18150..18578
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003941706.1"
                     /locus_tag="PXH69_RS10245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10240"
                     /product="protein-tyrosine phosphatase family protein"
                     /protein_id="WP_003941706.1"
                     /transl_table=11
                     /translation="MATWEPESIGILDLPSGRSIRGRGLRNPLPSGPLPTFGVYLTGKE
                     PPDTEWESEWVRWRDFWLPSDPDALRRALHEVWVRSETERVEIACGGGYGRTGTALAAL
                     AVMDGVPSKDATAYVRARYSPRAVEMPWQRRFVTRFTQ"
     gene            complement(18662..20047)
                     /locus_tag="PXH69_RS10250"
                     /old_locus_tag="PXH69_10245"
     CDS             complement(18662..20047)
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016933765.1"
                     /locus_tag="PXH69_RS10250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10245"
                     /product="3-deoxy-7-phosphoheptulonate synthase class II"
                     /protein_id="WP_007730070.1"
                     /transl_table=11
                     /translation="MNWTVDVPIDRLPELPPLPAGLRKQLDEALAKPAAQQPSWPADQA
                     AAMRTVLESVPPITVASEVEALQERLAQVARGEAFLLQGGDCAETFADNTEPHIKGNIR
                     TLLQMAVVLTYGSSMPVVKVARIAGQYAKPRSADIDSLGLKSYRGDMINSLVADEAVRA
                     HDPSRLVRAYANASAAMNLVRALTGAGMADLHKVHDWNREFVAASPAGARYEQLAAEID
                     RGLQFMNACGVTDPSLHQAQIFASHEALVLDYERAMLRLDNDSDHPKLYDLSAHFLWIG
                     DRTRQLDGAHIAFAELVSNPIGLKIGPSTTPEMAVEYVERLDPTNKPGRLTLISRMGNG
                     KVRDLLPAIIEKVQATGHQVIWQCDPMHGNTHEASTGYKTRHFDRIVDEVQGFFEVHNG
                     LGTHPGGIHVELTGENVTECLGGAQDISDLDLGGRYETACDPRLNTQQSLELAFLVAEM
                     LRG"
     misc_feature    complement(20080..20095)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.66"
                     /tool="antismash"
     gene            complement(20138..20629)
                     /locus_tag="PXH69_RS10255"
                     /old_locus_tag="PXH69_10250"
     CDS             complement(20138..20629)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012688083.1"
                     /locus_tag="PXH69_RS10255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10250"
                     /product="polyadenylate-specific 3'-exoribonuclease AS"
                     /protein_id="WP_003941683.1"
                     /transl_table=11
                     /translation="MRYFYDCEFIEDGRTIDLVSIGVVCEDGREYYAVSTEFDPARAGS
                     WVRKNVLPKLPQPSSPLWKSREKIRDDLLKFFVPRPMVVPELWAWVAAYDHVALCQLWG
                     DMTELPQSMPRYTRELRQFWEDNGSPALPSAPADAHDALADARHNLVKFDAISAARSLR
                     "
     gene            complement(20696..21502)
                     /locus_tag="PXH69_RS10260"
                     /old_locus_tag="PXH69_10255"
     CDS             complement(20696..21502)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003941692.1"
                     /locus_tag="PXH69_RS10260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10255"
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="WP_003941692.1"
                     /transl_table=11
                     /translation="MWYWLFKYVLLGPILWLLGRPTVKGHENIPTDGAAILASNHQAVL
                     DSFYLPLRVNRRITFLAKSEYFTGSGLKGAFQKWFFTAVGQVPIDRTGADAAQDALNAG
                     LKVLGSGSLLGIYPEGTRSPDGRLYKGKTGMARLALESGVKVIPVAMVGTDKMNPIGSR
                     MWRPAKVTVIVGEPIDFSRFEGMGGNRFVERAVTDEVMYKLMKLSGQEYVDIYAASLKN
                     QAPTKPEAAVDVPAEGGESVVDLVASAESKESAKSDKDSLPDAQAS"
     gene            complement(21597..22637)
                     /locus_tag="PXH69_RS10265"
                     /old_locus_tag="PXH69_10260"
     CDS             complement(21597..22637)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748895.1"
                     /locus_tag="PXH69_RS10265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10260"
                     /product="ROK family protein"
                     /protein_id="WP_020969875.1"
                     /transl_table=11
                     /translation="MSARRLKAVSDSTMDDILTVGIDVGGTSIRASVVDVDGQVLEMIQ
                     APTPQSARALEDGLDRVVRELVTRHEVSAVGLAVAGFITSDRSSVRFAPHLPWVDAPVG
                     SDLSKRLGLPVVLEHDANAAAFAEHRFGAAAGGRNVVMVAIGTGIGGALLINGELYRGS
                     HGVAPELGHIQVVPGGRQCACGKRGCWERYCSGTALVDTAIELLAADPAASTVLAREVA
                     VDPGSLTGRRIANAAQDGDPLALATIAEFTRWLAVGLAMVGDVYDPDLVVIAGGVASSA
                     PLFLDDAREQYATLLTGAKHRPLARIRSAQLGEAAGMVGAAALARSVVPQDLGGVDGAG
                     TTSAGL"
     gene            complement(22762..23157)
                     /locus_tag="PXH69_RS10270"
                     /old_locus_tag="PXH69_10265"
     CDS             complement(22762..23157)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748896.1"
                     /locus_tag="PXH69_RS10270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10265"
                     /product="hypothetical protein"
                     /protein_id="WP_042453569.1"
                     /transl_table=11
                     /translation="MSEEHERLVAEFRALAETVLTRLEPVLQKAAAATADVASDSASTD
                     TQPVFTGCSWCPVCALAALVRGEHHELLAFLAGQAAAFLALLREILDEFLGGPSGPDRG
                     PDGGPTTPGAERTRTAAFVPINVTVKD"
     gene            complement(23154..24404)
                     /locus_tag="PXH69_RS10275"
                     /old_locus_tag="PXH69_10270"
     CDS             complement(23154..24404)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1157: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730068.1"
                     /locus_tag="PXH69_RS10275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10270"
                     /product="ArsA-related P-loop ATPase"
                     /protein_id="WP_054826515.1"
                     /transl_table=11
                     /translation="MPEQRSRVQLFVGKGGVGTTTLAAATAVSAATDGARVLLVSIDQA
                     GSLADVLGVPNPRTTTSLTERLDVRQLDTSALLEDKFRGLSGLIDAAGTFGAGDHEHGS
                     SFEGLEPEELTGSLGIQDMLGLAEIVDLSDSGDYDVVIVDCPAAAEALRILGSPSMVSE
                     YLERLWPRHRRMVAVTGTDMRLLLLVSVVERVLASVDRIAVHLSDRENTGVRVVTSADG
                     VSVAATRRTLSGLALAGLRVDGIVVNNLVPQFNSSAGKGVDDSPAAQWLASIRAAQALV
                     VDELRGSTDGMSVTTVERACAEPVGLAALGEIAATFEGGTGTDSGTVGTADNIVVSLES
                     GTGVDSVYVMRMYLPLVDPSSLSLGRVEDDVLVGADGVRRRVRLASVLRRCVVNGAELD
                     GSYLIIRFSPDPAVWPV"
     gene            complement(24405..24842)
                     /locus_tag="PXH69_RS10280"
                     /old_locus_tag="PXH69_10275"
     CDS             complement(24405..24842)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (8-144). E-value:
                     4.3e-18. Score: 58.0. Matches aSDomain:
                     nrpspksdomains_PXH69_RS10280_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005247694.1"
                     /locus_tag="PXH69_RS10280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10275"
                     /product="SRPBCC family protein"
                     /protein_id="WP_003941701.1"
                     /transl_table=11
                     /translation="MAEKTKGLISIDAPADAVMDVIADFERYPEWVAAAKSVEVTAPGQ
                     GGRADRVRFVLDAGMVKDTYELQYSWAPDGMAVSWELISGEIQKSQFGSYTLEPGPNGT
                     TSVTYELTVDLTIPMIGLFKRKAEKIITDTALKELKKRVEG"
     aSDomain        complement(24411..24818)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PXH69_RS10280_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="4.30E-18"
                     /label="PXH69_RS10280_Polyketide_cyc2.1"
                     /locus_tag="PXH69_RS10280"
                     /protein_end="144"
                     /protein_start="8"
                     /score="58.0"
                     /tool="antismash"
                     /translation="ISIDAPADAVMDVIADFERYPEWVAAAKSVEVTAPGQGGRADRVR
                     FVLDAGMVKDTYELQYSWAPDGMAVSWELISGEIQKSQFGSYTLEPGPNGTTSVTYELT
                     VDLTIPMIGLFKRKAEKIITDTALKELKKRVE"
     misc_feature    24808..24821
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.45"
                     /tool="antismash"
     gene            complement(24906..25292)
                     /locus_tag="PXH69_RS10285"
                     /old_locus_tag="PXH69_10280"
     CDS             complement(24906..25292)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-55). E-value:
                     4.3e-08. Score: 25.6. Matches aSDomain:
                     nrpspksdomains_PXH69_RS10285_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748899.1"
                     /locus_tag="PXH69_RS10285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PXH69_10280"
                     /product="polyketide cyclase / dehydrase and lipid
                     transport"
                     /protein_id="WP_054827545.1"
                     /transl_table=11
                     /translation="MSSIQVADQTFIAAPPERVAELLSSRAQWRRWFSDLELEVREDRG
                     PAGFRWGVSGQLVGTMEVWLEPAMDGTIAHYFLHCEPVGVSPSDLATLDLAGMNRKRRV
                     DGKVMSFQLKRELEAGRAAGVAPD"
     aSDomain        complement(25128..25280)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PXH69_RS10285_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="4.30E-08"
                     /label="PXH69_RS10285_Polyketide_cyc2.1"
                     /locus_tag="PXH69_RS10285"
                     /protein_end="55"
                     /protein_start="4"
                     /score="25.6"
                     /tool="antismash"
                     /translation="QVADQTFIAAPPERVAELLSSRAQWRRWFSDLELEVREDRGPAGF
                     RWGVSG"
ORIGIN
        1 ctcgggctgc ggcgtctcgg tccgcgtgcc ggaagagtcg acagtcgact tcacgatccg
       61 cggaggaatt cgcacgccgt cgttggcaat ggcctggtac atcccggtca tctgcagggt
      121 tgtcatcgag agaccctgcc cgatcggcag gttcgcgaag gttccgccgg accactggtc
      181 gcgactcgga acgctgcccg cgctctcgcc gggaagtccg acgtcggtgc gttgtccgag
      241 gccgaacctg ttcagcatgt ctgcgtagcg atcctcgccc actcgctgag cgagcatcaa
      301 ggtgccgacg ttcgaggact ttccgaacac accggtagag gtgtacgggg ccacaccgtg
      361 atcccacgcg tccttgactg tggcaccgga catcgtgatg ctgcccggga cctgcagaac
      421 ttcgtccgga gttgtcttac cgtcctcgat ggccgctgct gcggtgacga tcttgttcac
      481 cgatccgggc tcgaacggcg tactgaccga cggattgccc atttcggctg tcggcgcgtt
      541 cttgtcaatg ccgattgcgg ggttgaaggt gctgtcgttg gacatggcca acacctgtcc
      601 cgtcttggag tccatgacca caaccgaagc gttctttgcg cccgacttgt ccttggcgat
      661 ctggacctgc tgctgaacgt agaactggag gtccgaatcg atggtcagct cgacacccga
      721 accgttgact gccggttgct tgtcacgcca gctaccgggg atcacagcgc cgtcggaacc
      781 gcggtcgtac gtttcggatc catcggttcc ggcgagcgtg gagtccatcg aatcttcgag
      841 accgagcaaa ccgtgcccgt cccagccggt cgcgccgacg agattcgcgg ccagagagcc
      901 accggggtac tcgcggatgt cctgacgctc gaggccgacc tcccggaact tgtccgagat
      961 ctcggcagca accgccggat ccacactgcg cgcgaggtac gtgaaagtct cgttgctgtt
     1021 catcttctga agcagatctt tttccggaac ggtatcgccg agcttggcgt ggattccggc
     1081 ggcgatctcg gcgaggcgat cgctcacttc cggcgcctgc ttgtcaccct cggctccctg
     1141 ctcgatgctc ttggcgcgcg cttcctcgag ttccttgcgt acccgcaccg gctggaaagt
     1201 cagcgccttg gcttccatgg tgaaggcgag ggggtttccg ttgcgatcgg ttatcgagcc
     1261 acgtacagcc ggatcgacct gggtcgtggt tcgttgattg gcagattccg cagccagact
     1321 cggcgcgtcg attccctgaa tccacaagag ctgcaatgcc gcaacggcga gcgcaccaca
     1381 catggtgata cgaccgactc gctgacgaaa cggaaatgag gcggtggccg agcggcgcgg
     1441 acgccgaccg gggttgttac gggagttctg actcaccgac gttcctcagg cggagcaggc
     1501 accgccgtcg tggtggcggg tgctgtcgtc gtggggatca caggaaccaa ttgttcactc
     1561 tgcgcgaggt ttcgcgtgtt attcggaacg ctcggcgtgg ctccgggagc aaccggcgtt
     1621 gtggtgcgcg ggggtgtcgc agtcggtgcg ggcaccgatg tgggcgcatc gagcggcggc
     1681 atagctccgg cagtcgcggg agtcggcgtt ccgacgacct cgaccgaacc gtccggatga
     1741 actaccagtc gtgctgggtc cttggcgggg accatgccga gagcgcttgc ctgatttgcc
     1801 aactccggag ccgagttacg cgactggaag tcacgttcga gcgctgcttt ctgctcgacc
     1861 aaagactggt tgtatgcacg tgcatcactg agttggtacg aatcctcggc agcgcgagtg
     1921 gtcagcagca gagtcaccgc gagaccgatg gacagaagtc cgatgacgga ggccacgaac
     1981 ggcactctcc ccttgagcat cgcccgagga gagatagacg ggccggcagc agcgacagtt
     2041 ccggtccggc ctgccgcccg tgcggtgcgc ttgtcgtatg cacgttgcgc tgcaccggat
     2101 ttgccctgac gactcatgcc cgcctcctgg aaatgcgttc tgcggcacgc aaacgcaccg
     2161 gagctgatcg tgggttctct tcgatttcct gctctgacgc acgttctgcg ccacgggtga
     2221 gaatgcggaa ctccggtccc atacccggca actcgaccgg tagtccttca ggactggtgg
     2281 acttcgagcg gggaaccaac tccgccttca caactcgatc ctcgagcgac tggtaggaca
     2341 tgaacaccac tcgcccaccg actgccagtg cgtcgagccc ggcaggaacg gctgcacgaa
     2401 gcgaatccaa ctcggcattg acttcgatcc gcagcgcttg gaaggtgcgc ttggccgggt
     2461 gtccccccgt acgccgcgtg gctgccggga ttgttcggta cagcaattcg accagagctg
     2521 cactggtggt gaagggttca cgctcacgct gccgaaggat ctcggacgca atctttcccg
     2581 cgaaccgttc ttcgccgtac gtgctcagaa tgcgagcaag gtcgccgtga ctgtaggtgt
     2641 tcaggacctc tgccgcggtc agcccgaccg tctgatccat ccgcatgtcg agaggagcgt
     2701 cgatcgagta cgcaaaacct cggtcggctt cgtccaactg catcgacgac acacccagat
     2761 cgaaaaggat cgcgtgaacc gactccgtcg acggcagacc tgcctgttcg agcgcgtcct
     2821 cgatcccgtc gtacgtggtg tgcacgaacg tcgttcggtc cgcgaatggc gccagacgct
     2881 cggaagcgat ccggagtgcg ttggtgtcgc gatcgagacc gatgaggtga aggcccgggt
     2941 acttgcccag gaagaattcg gagtggccac cgagccccaa cgtcgcatcg atcatgtatg
     3001 cgcccgctcc accgtcaccg acggcggtga tggcagggcc gagaagatcg tcggcgcggt
     3061 gaagaagtac agggacgtgc gcgaagccat cggcatccga gggttcgttc acctcgtgat
     3121 ccaccatgat tgctccggct cctactttca tgatttccga tgacttttcg aaaaggtgct
     3181 gactttccga gaaggcgatg actgttcgag aaggcgaatg cttcgaggtc cctgcccgaa
     3241 ggagaacctg gcgctgggga agtgcgtcag ggtctttccg ggcagaggcc tcgcggcatt
     3301 cgccgggggc tcttcgccta gacgatctcg ctgagagatt cgcctgttgc ctgcgaatag
     3361 tcctcttcgt tgtctccgag atacctctcc caggctgcta gatcccagat ctcgaggtaa
     3421 tcgacggagc cggtcactac gcattccttg gacaggtttg cgtaacgccg atgatcagcc
     3481 gagagggtga ttcgcccctg ggcatcggcg tgctgttcat ctgtgccggc ggccagggca
     3541 cggacatacg cccgagctgc cggatcattg cgtggagctg ccgctgcctt tcgagcaagc
     3601 ttgacgaact cgtcccgggg gtagatggcg aggctgtgat cctgactctt ggtgatcatc
     3661 aatcctcctg ccagttcgtc tcggaacttt gccggcaacg tgagccgacc tttgtcgtcg
     3721 agcttcggcg tgaaggtacc gaggaacact cgacacctcc tgcgagcttg cgctgaaacc
     3781 ctccctatcg agcggatcgt gcttcagctc tccgcccgaa cccacagtac cccactttcc
     3841 cccacaaaca aggagcacat ggtccctatt cagcatcatt tgctgataaa tagcaggtca
     3901 gcgcaggtgg ggagacgtgg gggaaatttg taaccgtgtc ccggcccaca ccgccgtcag
     3961 atcgaccctt tacgccacga tctgttgctc ccccacacaa aatcgcagta caagcgcggt
     4021 tttcgaatag acgtgagcgg gacgaggtct ggtcgtgcgc tgcagttcga ccagggtgga
     4081 ggaaagtgga gggccgagtg gagcgaagtg gaggaagccc gcgggcatgc cctgaggcag
     4141 caggagtggc gagtgattcg ctcgcacgtc actgattcac tcgatggatt gccggcgcac
     4201 acgcacaaca cccacagcaa cggcgtgtgg cggtcggcaa ccttggttgc cgaccgccac
     4261 acgtgtggtc gtccgtgccc tgaagagggc gtcacgtccg aactgcatca ctctcgaagt
     4321 acgcccgaag aagggcggga gagctagtcc tgctcgaacc tgcgtttgaa tcgatcttcc
     4381 atccgcgacg agaatccgcc gccggacttc cggccgcgtc cccgcccgga tccgccggca
     4441 ctacccctac ccggcggacc ggagggatga ttgccacctt cggaagcgga gtcggcggcc
     4501 ggcgcagact tacgtccacc accccagagg aacaacaccc ctgcgccgaa catgaacaag
     4561 aaaccgaaca ggctgatgat cggaaaaccg cccggcttga gcgggagtgc aacccccgcg
     4621 atcagcagga ccagacccag cacgaataga gccgctgctt ggaaccgccg tctactcgac
     4681 ggcgcccgca tacggccgcc cctcacattg gaggcgaact tggggtcttc ggcatagaga
     4741 gcgctctcga tctgatcgag catgcgctgc tcgtgctcgg agagtggcac ggtacctccc
     4801 ccggcactgg aagtttggca accaccccac ggtgtgaggc ggcgggtaat caagttggac
     4861 gattacctgt tttcataata cgagcagttt aggtctcgga ccaccaactc cgggtacgag
     4921 ttccgccaca agcgtacgta ttcgtgccga agggccccga ttcggctcca tttgcctgtg
     4981 cggaccagga aattccccgg aaacaactgc cgacacggac catttgttca cgacgctcgc
     5041 aaatgctcgg acgcgtcctg accgatgaaa tcttcgaccg ccgtgagaaa acggccgacc
     5101 tcggcgaaga atgcgtcgga atcggagtcc gtgatcacga tcgacacgcc ggtttccacg
     5161 gccgcacgcg tagaggacca ccctgcgaag aacttcgacc acgctccgaa cgcgggcgct
     5221 gcggcgtcca tcagaaccca cgcgtttccg cttcgcttgc gcttcgagcc ggcaccggca
     5281 ggagctgcgg ccaacactgc cccggcacca cgtagggccg ccaggtaggc acaccggaac
     5341 cggtcggcag gatcgcccgc cccaatcgct tcctcgagaa gcgcatccgc cttccggagc
     5401 agcccccacg ccacaccgga ctttcccact cgagcagtgc ggtcgctgac gtccctcgcg
     5461 ccgaaggacc gcctcgccga catcggcaat cgagaaattg cggcatccga cggactcgac
     5521 aactcggcag gaagagttcg ttggcacttc acacgttcag gcttcacacg ctcggacatc
     5581 ggggcacctc ctgcaccgtg aggatccaag accaggtggg ccggagatgc ccgcttccct
     5641 tcgggcatct ccggatcacc cacatcgaac atctgttcga cctattcaat ataactgcac
     5701 ccaccgacac gccgtcaaga gaagaggtga gaccggtcga cccgcagatc gcctggacac
     5761 cacatacggt cgacctcgat cgcgcagaat tcgtgagtcg actccacgag gcactggccg
     5821 tgtacgtcac cgcgatggac tatccgcgag gaaccgagtt ccatcgcgca ccgatgtggc
     5881 aggagcacgc gaaccggcct ggctggaagg cagtcggcgc tttggcggtt cctcagcaac
     5941 cgtcacacga aaatctgccg ctggtgggga tcgcttacgg gtatcgcggg agcccggacc
     6001 agtggtggca tcaacaggta ctgcacgggc ttcggcgctc gggtcgtccc cagagcgaga
     6061 tcgacgcgat tctgagcgac tacttcgaac tcaccgaact ccacgtgcat ccgaacggac
     6121 aaggtcaccg gttgggcgaa tcgctcttgc gtcacctcct cgtcgatcga cccgaacgca
     6181 gtgttctgtt gtcgacaccc gaggtgtacg acgaggacaa ccgagcctgg cggctgtacc
     6241 gtcgcctcgg ctttcgtgac gtgctccgca gatttcgttt tgccggcgac aaccggccgt
     6301 tcgcagtcct cggccgtgga ctcccgctgt gagcgcactt ctcgacgccg tcgtcgtcgg
     6361 ctccggacac aacgcgctcg catcggccgc ctacctcgca cgcgagggtt ggtcggtcga
     6421 ggttctggag aaggacacgg ttctcggcgg cgccgtctcg accgtcgagc gatttcccgg
     6481 atacaaggtg gaccgggggt cgtcggcaca cctcatgatc cgacacagcg gcatcatcga
     6541 ggaactcgga ctcggcgcgc acggactgcg ctacatcgac tgtgacccgt gggcgttcgc
     6601 gccgcccgcc ccgggcaccg acgggccggg catcgtgttt caccgcgacc tcgacgcaac
     6661 ctgctggtcc atcgaacgag catgcgggac aaaggacgcc gactcctacc ggcgattcgt
     6721 cgcggtctgg tcggagcgca gtcgacatgt catgaaagcg ttttccgcac cgcccaccgg
     6781 atcgaacctg atcggtgcgt tcggaggtct cgccaccgca cgcggcaaca gcgaactgtc
     6841 tcggcagttc ctcgcgcctg gcgacgcact gctcgacgag tatttcgaca gtgaggcact
     6901 caaagcagcg cttgcgtggt tcggcgccca gtccgggcct gcgatgtcgg aaccgggaac
     6961 cgctccgatg gtcggcttcg cggccctcat gcacgtcttg ccgccagggc gagcagtcgg
     7021 tggaagcggc gcactgagtg ctgcgttggc ctcccggatg gctgtcgacg gcgccacggt
     7081 cgcgctcggt gacggcgtga cgtcgatccg tcgaaactcg agtcactgga ccgccacaac
     7141 cgagagcggt cgagaagttc acgctcgcaa ggtaatcgcc gggtgccaca tcctgaccac
     7201 gctcgacctc ctgggccgag ggggcttcga ccgaaccacg ctcgatcact ggcggcggaa
     7261 aatcagggtc ggccccggca tcggcgcggt acttcgactg gcgacatccg cgcttccgtc
     7321 gtaccgcggc gacgccacga cacgggaaag tacctcggga ttgcaattac tcgtctccga
     7381 tcgcgcacac ttgcgcactg cacacggcgc agcactggcg ggggaacttc ctcctcgccc
     7441 tgcggttctc ggaatgagtt tcagcggaat cgatcccacg atcgccccgg ccggtcggca
     7501 tcaggtgaca ctgtggtcgc agtggcaacc gtatcgcctc agtggacatc gcgattgggc
     7561 atcggtcgcc gaggcggagg ccgaccggat cgtcggcgag atggaggctt tcgcacccgg
     7621 gttcgccgat tccgtcctcg accggttcat tcagaccccc cgggacatcg agtcggaatt
     7681 ggggatgatc ggcggaaatg tcatgcacgt cgagatgtca ctcgatcaga tgatgttgtg
     7741 gcgaccgctt ccggaactgt ccggccatcg cgttccggga gcagacgggt tgtatctgac
     7801 cggagcatcg actcatcccg gtggcggtgt gtccggagcc agcggtcgca gtgcggctcg
     7861 aatcgcactg tcggacagcc gccggggcgc gactcgtcgt tggatgcgtc gttcgagcag
     7921 gtcgtgaagg tcacccgccg aacttcaccc gccgacacgc ccccgcctcg atgactggct
     7981 acgccacggc tggcacgatg accactgtgc aacagtccac cgatcccgcc gccaagccga
     8041 ccagtcggaa acgtttcctg acggttgccg cgctcgccct catgcttgtt cccttgcttg
     8101 ccgggtgcat ccgcgtgcag gtgtcgatgg gagtgtccgc gaacgatcgt gtgaccggac
     8161 aggtggtagc tgccgctatt ccggcgaacg aggcggacaa gggtccgcag ctgaccccac
     8221 cttcgtcgct ggaggacaag atacgggttc aggagtacaa gaaggacggg tacgtcggca
     8281 gccaggcgtt cttcagcgac ttgtccttcg gtgacgtcgc ccaactgggc tccatgtacg
     8341 ccgaggggtc cgggtcgttc cagatcaccc tcaagcgatc cggggacacc gtcacgctcg
     8401 acggcaaggc agacctgaag acggttccaa ctcagggcgc cgacgtccag gtcagcatcg
     8461 ccttcccggc acgggtcggc acgaccaacg gaacacgaga cggcgattcc cgggtgtcgt
     8521 ggaccttgcc cgccggcgag gtgtccacga tgcgcgccga ggtcaactac gcggacccaa
     8581 gcacccgaag cttcgccggg tgggcaggaa tcatggccgg gctggcgctc ggtgtcgcga
     8641 ttgtcgtcgg tgcgatggcc tggatggcgc gcaatcgagc accgatcaag cgcgcgcccg
     8701 ccgcgaaagc accggctatg aagacgcctg tcacgaaatc acctgccagc aagcaagctg
     8761 acaccaggaa tccgaaaaac accacgaagt agcgcctggc gattgccccc ctcgattggt
     8821 gtcgagcggg gcaaccggga tcagacggct tgcgctgtcc cgacagaagt gtcgggggtg
     8881 agaccgagtc gctcgaggac ctcactggtg gcgcgcgcga agttcaacgt gatgaagtgc
     8941 aggcacggag cgccttcggc gatcaaccgc tcacccatct cggtggccag atcgatgccg
     9001 agttcgcgga ccgctgcacg gttctcgtcc ggaccgcttc cggccgcggc gtcgaatcga
     9061 cgctcgagag cggggggcaa tgacgagccc gagagctcga gcatgcgccg caccgagcgt
     9121 agcgacgtca ccggcatgat ctccgggatg atcggcttgg cgccctgttc tgcgtcgtac
     9181 gcactcaccc ggtcacgaag acgcaggtag tcctccacgt cgaagaacat ctgagtgatc
     9241 gagtactcgg cgccggcacg caacttcgac accaggtact tcgtgtcgta tgccaagtcc
     9301 ggagcgcggt agtgcccctc ggggaacgac gcgacgccga cgtggaagtc gcccaggtca
     9361 cggaccatcc gcacgagttc ctcggcgtac tcgacgcctt cgggatgctt cttccactcg
     9421 ccgagcggat cgccgggcgg atcgccgcgc aatacgagga tgttgctgat cccacgatcg
     9481 gcgtaggcac cgaccatggc gcgaagctct tcggtgctgt gtgagacagc agtcaggtga
     9541 gcaaccggca gcagggtcgt ctcttcggca agttcgccgg tgacacgcac cgtacgatcg
     9601 cgcgtcgagc cacctgcgcc gtaggtcatc gagacgaacg ccggtccgag ccgctcgaag
     9661 gtacgcaccg cacgccacag gcgcgcttcg gcgtccgcgt cacgcggcgg cgaaaactcg
     9721 accgagaacg gaatacggct acctgtcgag gaagcgatcc gatcgacgat cgacggtgtt
     9781 cgggtggccc acccctcgct ggagcggccc ctgactggat cgaatgtcac cggtcaagca
     9841 tatgttttcc agctgcaaac aagctcatcg cccaggactg cgtatcccga atgtcaggat
     9901 cacgcagttc acggcccgac ccgccgttga ttccaacccc cactaagctg ggctccaagc
     9961 tcgcttccgt gtaaccatcc ggcgcgagaa cataccgatc ttggaggcca ccctgtccgc
    10021 aggaaccgcg cgcgttggac agagttcgac caacaccgca ccgcatccga cctcactcga
    10081 actgccaggt ctgttcgaag cagcgctccg cgacttcttc gcttcacgcc gcgaactcgt
    10141 ctcgaacatc ggcggtggat acgaggaggc cgtcagcacc ctcgaggcct tcgtcctgcg
    10201 cggaggaaag cgcgtccgac cgtcgttcgc ctggacggga tggctcggcg ccggaggcga
    10261 cccgaacggt aaggacgcag acgcggtgat tcgtgcgtgc gccgccctcg aactggtgca
    10321 ggcctgcgcg ctcgtccacg acgacatcat cgacgcatcc acgaccaggc gcggcttccc
    10381 gaccgttcac gtcgaattcg aggaccagca ccgagacgag gagtggagcg gcgattccgc
    10441 gcacttcggc gaggccgtcg ccattcttct cggcgacctg gccttggcct gggcggacga
    10501 catgatccga gaatccggga tcagccccga ggcggccgca cgagtgagcc cggtctggtc
    10561 ggcaatgcgc accgaggtgc tcggtggcca attcctcgac atcagcaatg aagcccgagg
    10621 cgacgagacc gtcgaggcag ccatgcgggt caaccgctac aagaccgccg cgtacacgat
    10681 cgaacgccca ctgcacctcg gcgccgcgct gttcggtgcg gacgccgagt tggtcgatgc
    10741 gtaccggacc ttcggcacgg acatcggtat cgccttccaa cttcgcgacg acctgctcgg
    10801 tgtcttcgga gatccgtccg tcacgggcaa accgtcgggc gacgatctca tcgccggtaa
    10861 gcgaactgtc ctgttcgcga tggcgcttgc ccgcgccgac gccgcagatc cggctgcagc
    10921 agaactgctc cgcaacggaa tcggcacgca gctgaccgac accgaggtcg acactctgcg
    10981 ccaggtgatc accgatctgg gcgccgtcac cgacgtcgaa acgcagatcg acaccctcgt
    11041 cgaggcagct gcgaacgccc tcgactcgag cacggcaacg gcagagtcca aggctcgcct
    11101 gaccgacatg gcgatcgcgg ccacgaagcg aagctactga ccgtggcaca cgtgcaccgc
    11161 actcgaaccg tcagctcgcc gaccgatcga gtcgtgatcg tcggcgcggg acttgccgga
    11221 ctgtctgcgg ggttgtatct gcgtggcgcc ggccgcgacg tcacgattct cgagagcaac
    11281 agctcggtcg gtgggcgagt cggtgtctac cagggcaatg actacagcat cgacaacggc
    11341 gcaacggtgc tcacgatgcc cgaactcgtc gaagacgcgc ttgccgccgt cggtgccgac
    11401 ccagcctcga caaaccccaa attcgttgtg cacaagctcg atccgacgta ccacgcgcga
    11461 ttcgcagacg gcaccgctct cgatgtccac gccgatccag aagacatggc tgccgaggtc
    11521 tcccgtgtct gcgggccgga agaagcgcag cgataccgtg cgttgcggcg atggctgaac
    11581 cggatcttcg acgcggaatt cgaccgcttc atggacgccg acttcgattc tcccctcgga
    11641 ctggtcaatt cgcgtgacgc agtcaaagat ctgagccggc tcgtcgcact gggaggattc
    11701 gggacactgg gcgggcaggt ggatcgcaag atccgcgacc ctcgcctccg gcggatcttc
    11761 accttccaag cgctgtatgc gggcgttgct ccgtctcggg ccctcgcggt gtacggggcg
    11821 atcgctcaca tggacacctc actcggcgtc tacttccccg agggcggaat gcgcacgatc
    11881 gccgagtcga tggccgacgc cttcaccgag gccggcggaa ttctgcatct cggccgcact
    11941 gtcgaacgcc tcgaggtgag cggacggcgc gtgcacaccg ttcacacacg cgacggcgag
    12001 cgcttcgact gtgacgccgc cgtcctcact cccgacatgg ccgtcacgga ctcgctcttg
    12061 cgcccgcata cgcgattgcg tccgcgcccg gtgcgtacat cgccgtccgc tgtcgtgatt
    12121 cacggcactg tttcctccgc ggtcgccgac gaatggcccg cgcagcgaca ccacatgatc
    12181 gacttcggcg aggcgtggaa gcgtaccttc gccgagatca cggcacgccg cggccgcggg
    12241 cgactgatga gtgatccgtc actgctcgtc acccgaccgg cacagaccga tccgagcctg
    12301 gccttctcgc gagacggccg aatccgtgaa ccgctgtcag tcctcgcgcc gtgtccgaat
    12361 ctggacagtg caagtctcga ctggtcgact ctcggcccgc cctacgtgcg cgaaatcatc
    12421 ctcacgctgc aagaacgtgg ctacacggga ctggtcgaag ggttcgagat cgatcacgtc
    12481 gacaccccgc agacctggct cgagaagggc atggccgcgg gtagcccgtt cgcagcggca
    12541 cacaccttca cccagacggg gccgttccga cgcaagaacc tcgcccgcgg cttcgacaac
    12601 gtcgttctcg ccggatcggg aaccgttccg ggggtgggag taccgaccgt tctgctgtcc
    12661 ggacggctcg ccgccgaacg tattaccggt acacgcgagc gagccagcgc ggtgggcact
    12721 cgtgcgagca actaaactag cccctcgtaa ccgaccattc atccacgatt caccgactcg
    12781 ggcgctgcat gcgccgatcg acaccgatct cctcggggga ggaacctgca ccgatgacgt
    12841 cctctgccgc agccactgaa agaccgtggc acctaagggc cgccaatttc cttcggactc
    12901 ccgaaggtca cagtgcactg ctcggtttct tcggcgcagt catgatcact ttcggcggat
    12961 tcggtgccgg tagcgtccgg cgccaagatc cgctgctcga gtcgatgcat ctgtcctggc
    13021 tccgtttcgg acacggatcg attctgtcgg cggccatcgt ctggatcggt gtcctgtgca
    13081 tgatcgccgc ctgggttcga ctgggccgct cgactctgcg cggtgacgtc tcgttgcgcg
    13141 gcctgcgcta cgtcgtcccg gtctggacgt ttccgctgct gttcgcggtg cccatgttca
    13201 gccgtgacgc ctactcctac ctggcgcaag gcgcgttgtt gcgcaacggc ttcgacccgt
    13261 atgccgtcgg ccccgtcgtc aatccgggaa tcctgctcga caacgtctcc aacgtgtgga
    13321 cgacgacaac taccccgtac ggtccggttc accttctcct tgccgacgcc atcgttcggc
    13381 tgaccggtga gaacgtcatc gccggcacga tgctgttgcg gatcacgatg ctccccggac
    13441 tcgccctgat gatgtgggcc gttccccatc tcgcgacgaa gctcggcgga aacacctcga
    13501 tcgccctgtg gctcgcagta ctcaatcccc tcgtcctgat ccacctgatc ggcggcgttc
    13561 acaacgagat gctcatggtc ggcctcatgg ccgcaggcat tgcgctcgct ctcgaacgca
    13621 agcacctctt cgggatcggg ctgatcgcgc tcgccgtcgc gatcaaggca accgcaggcg
    13681 tcgcacttcc cttcatagtc tggatctgga tgatccacga gcgggaggac gccgcagccg
    13741 ccgggcaaga accggcgtca ccgatccgat cgttcgtcaa aacggccggc gcaggtttcg
    13801 cggtgttcgt ggcggtactc ggatccacct cactgatcgc cggagtcggc ctcggctgga
    13861 cgacggcact ctccggttcg gcaaagatca tcaactggct ctcgctgccc acgatcgtgg
    13921 cgcacatcgg aaccatggca acctcctggt tcgccggcga ccatttcaac gacatcctcg
    13981 aagtctcccg gaccatctcg gcggttgtgt tgatcgcgat catcgccgtc gtgtggtggc
    14041 gctaccgcaa gaccgagcgc gacgccgtca tgggcatcgt gatcgtgatg gtcgccatcg
    14101 tcgttctgtc ccccgcagca ctcccctggt actactcctg gccgctggca gtagctgccg
    14161 gtttcgcaat gtcgccgacg actctcgccg tactgaccgg gctgtccacc tggctgatgc
    14221 tggtgttcca gccggacgga tcgatcggcc tgtacacctt ccctcacgtg gctctggcca
    14281 tcgtcgctgc cgtgatcgcg gcgatgtcct tgcagacgga agatccactg cgacttcgtg
    14341 gacgcaaaca cgagaaaccg atcgaaatga cgtcagccgc ctcggcgccc tcgacgtcag
    14401 gatctgcgtg atccgcgtgt catgaacgca ctgcctgcgt cctatgaatt ctgcgaggac
    14461 gtgacgaggg aacacggccg aacgtacttt ctggccaccc ggttgttgcc cgaacctcga
    14521 cgccgcgcag ttcacgcgct ctacgcattt gctcgcgtcg tcgacgacgt cgtggacgaa
    14581 ccctcgggtc cgcatgaacg aggcacggtg ctcgccgacg tcgaacgtgc agccgtcaac
    14641 gcactcgaca accccactgt gacaggtgac gttccgtcga cggttcccct cgacctgaca
    14701 cgcgtactcc ccgccttcgc cgatgctgtg aagacgttcg acatcccgcg cgcatacttc
    14761 gacgccttct tcgagtccat gcggatggac gcccccgaca cggcgaagtt tcgacccgtc
    14821 tacgacacga tggacgaact cagcgagtac atgtacggtt ccgccgtcgt catcggtttg
    14881 cagatgctcc cgattctcgg agtgagcgtt ccgcagcagg aagcggtagt gcccgcgtcg
    14941 aatctcggtg aggcgtttca gctgaccaac ttcatccgcg acgtcggtga agacctcgac
    15001 cggggacgtc tgtatctacc ggcaggcgag ttcgccgcat tcggggtcga catcgagatg
    15061 ctcgagcacg ggcgcagaac cggaacggtg gacgttcggg tcaagcgcgc gctggcacac
    15121 ttcattgccg tgacgcgggg gcggtatcgg tctgccgaat ctggcatccc gatgctcgat
    15181 cggcgggtcc agccgtcgat ccgcacggct ttcgtgttgt acggagcaat tctcgaccag
    15241 gtcgagcgcg ccgacttccg gatactgcat cgacgtgtgt ccgttcccgg acgcacgcga
    15301 cttcgagtcg ctgcgccggg tctggtccgg tcggcaacct acgcggcgaa aaaccgcatg
    15361 cggtgagttg tcagaaggcc ggcagctcag aaagccatgg cctgtgcgcg gcggatgacc
    15421 tcacgcgcga gatcaccatg cagtgcgtcc accgggcgcc ccggcaggga atcgtcggcc
    15481 aggaacaacc agcggaggat ttcgacatcg gtgtagccgc cgtcgtgcag caccgccagc
    15541 agaccgggca gccacttgac gatctggccg tcctcgccga agaacacttc ggggacaccg
    15601 agaacgccat gccgcttgac tgcgatgatc ttgtgatcgc gaagcaactg gtgaaccttg
    15661 ctcaccggca acccgacgtt cttcgccaca tccaccagct ggaacaggga aaccgaagaa
    15721 tccaggacat catcacaata aggaatcgcg ctcaccgcga gaagtttatc cggtccggcg
    15781 agcccgctgt gtaccgcccg gtgcagtgct cgaaactgcc gctccgctca ggtcacagcg
    15841 ctctgtgacg ttctcgagac ttccgcgtcg gtatcgctgg ctacgatgga cgggatgcgg
    15901 cgtatcagta accgggattt cgcggtggat gtaaatgggt gccctcactg cgggagccag
    15961 tacgcggtaa acaaccaccc acatgccgac agctaccacc tagaccgcaa gcacgcagat
    16021 cgcaagcacg gaggaacagt cattacggag gtcgagggtt gatcggcgaa atgctcgagc
    16081 gccgctatcg agtggacgca ccgatcgcgc gcggcggtat gtcgaccgtg tatcgaggcc
    16141 tcgatacacg gttggatcga cctgtcgcga tcaaggtgat ggatccgcaa ttcgccggcg
    16201 atccagcgtt cctgactcgt ttcgagttcg aagcccgggc cgtggcccga ctcaagcatc
    16261 cggcccttgt ggccgtctac gaccaaggca gcgatcgcaa tcacgtgttc ctcgtgatgg
    16321 aactcgtcga cggcggaacc ttgcgtgaac tccttcgtga gcgcggaccg atgccgccac
    16381 acgcagtcgc tgcagtcgtg gcacctgtcc tggacgcgtt ggcggtggcg catcgagcgg
    16441 gactggtgca ccgtgacgtc aaacccgaga acatcttgat ctcggacacc ggcgaagtga
    16501 agatcgccga cttcggattg gtgcgtgcag ctgcggcagc aaccaccacc tccaacagcg
    16561 tgatcctcgg caccgcggcc tatctgtcgc cggaacaggt gacgtcagga attgccgaca
    16621 ctcgaagcga cgtctattcc accggcgtgt tgatgttcga acttctcacc ggtacaacac
    16681 cgttcaccgg cgatacgtca ctctccatcg cctaccaacg catccacgac gatgtcccgc
    16741 gcccaggttc acgtatcccc ggtgtaccgg cgcagttcga tcgtctggtt gccgaagcca
    16801 ctcaccgcga gcccgcacat cgtttcgccg acgccggtga gatggcagct gcacttcgca
    16861 gtgtgagcga gcaactggaa cttccgtcat accgcgttcc cgctccgcgt cgaagcgccc
    16921 agcaccagag cgcgcaagtt gccccggccc ggccacaacc ggcgcctgcg cctcccacgg
    16981 aggtacaccc gaactctgct gcgcgcccga accctgctgc cacgacggta ttggcgtccg
    17041 gcgtggcccc ggctgtggca gccaccacgg cgctcggcac gggctctcct ccccctggcg
    17101 gtatccagca cactcgcgcg gtcaccgcac aaactgctcg tccggcgacg gtcgacggcg
    17161 actcggattt cgacgacggt tccgatttcg gcgacgacca cccggggcac gacgatccgc
    17221 atgctcattt tgtcgaggca cgtcgtaaat cgcgacgagc caccctgatc tggctgctcg
    17281 tcatcgcggt cctcgcgctc gcgttgggct tcggcggatg gtggatgggc tcgggccgct
    17341 atacagctgt tccctcgatc gacgggctga ccaaggacac tgcggtcacc gctctgcagg
    17401 acgccgggct ctcccccgac gtccagggtc agtactccga cgcccaaccc atcgacacgg
    17461 tgatcgggac agacccggcc tccggctcga gggttaccaa aggctcgacc gtggcgttac
    17521 tgacttcgct cgggcgtccg actgtcccgc ccattccggc cggcggcgac gtctcggccc
    17581 tgggcgcaca actcgccgac cgcactctcg tcgcggtcga cggcggggac acattcagct
    17641 ccaagatccc gatcggcggc gtggccgcgc tcgacccggc accgggaacc gaagttgccg
    17701 tgggctcctc ggtcaaggtc atcacgtcca aagggtcacc gcccgtagac attcccgatg
    17761 tgaagggcat gtccgagaac gctgcgcgcg ccgccctcga caaggtaggc atctcagtca
    17821 gcaccaccag aacaacgttc gacgacgccg tcgagggcgg tagcgtgatc ggcaccgatc
    17881 ccgcagtcgg gtcctccgtc aacgccggca cctccgtggt tctcctcatc tccgattccg
    17941 tcaaggttcc ctcgctgatc ggccgctccg tctcctcagc acgcgaagaa ctcggccgcc
    18001 tcggcctcga gatcaccgtg cgtcagctca cccagaacga cagctcggtc atcatcagcc
    18061 agagcgtcaa gaacgacctc gttgccaagg gcaccgacat cagcgtcgtc gcaattccct
    18121 gacagtccgc ttcggcctaa tctgaattca tggccacgtg ggaacccgag agcattggga
    18181 tactcgactt gccgtcgggg agatcgattc ggggtcgagg actccgcaat ccacttcctt
    18241 ccggacctct ccccaccttc ggcgtctatc tgaccggcaa agaacctccc gacaccgaat
    18301 gggagtcgga gtgggtccgc tggcgagatt tctggttgcc gagcgatccc gatgcgctgc
    18361 gcagggcctt gcacgaagtg tgggtgcgct cggaaaccga aagagtcgag atcgcttgtg
    18421 gtggtggata cggccgcacc ggaacagcgt tggccgctct tgccgtcatg gacggagtgc
    18481 ccagtaagga cgccaccgcg tacgttcgcg cacgttactc acctcgcgcc gtcgaaatgc
    18541 cctggcagcg ccgattcgtc acacgattca cgcaatagcg aacgccccca cctgcgcgag
    18601 cgggtgaggg cggttgccga aaatctatgc cggcgcgaat cagcttcggc gaagcaaggt
    18661 ttcagcctcg cagcatctcg gccacgagga acgcgagctc caacgactgt tgggtgttca
    18721 atcgggggtc gcacgccgtc tcgtagcgac cgccgagatc gaggtcggag atgtcctgcg
    18781 cgccgccgag gcactcggtg acgttctcac cggtcagctc gacgtggatg ccacccggat
    18841 gcgtgccgag accgttgtgg acctcgaaga atccctggac ctcgtcgacg atgcggtcga
    18901 agtggcgcgt cttgtacccg gtggaggctt cgtgggtgtt gccgtgcatc ggatcgcact
    18961 gccagatgac ctggtgaccg gtggcttgga ccttctcgat gatcgccggc agcaggtcgc
    19021 ggaccttgcc gttgcccatg cgcgagatca gagtcagacg acctggcttg ttggtggggt
    19081 cgagacgctc gacgtattcc accgccattt ccggcgtcgt gctcgggccg atcttgaggc
    19141 cgatcgggtt ggacaccaac tcggcgaagg cgatgtgcgc gccgtcgagc tgacgagtgc
    19201 ggtcaccgat ccagaggaag tgagccgaca ggtcgtagag cttggggtga tcgctgtcgt
    19261 tgtcgagacg cagcatcgcg cgctcgtagt cgagaaccag agcctcgtgg ctggcaaaga
    19321 tctgtgcctg gtgcaggctc ggatcggtga cgccacacgc gttcatgaac tgcaggccgc
    19381 ggtcgatctc ggctgccagt tgctcgtagc gtgcgcccgc gggagacgct gcgacgaatt
    19441 cgcggttcca atcgtgcacc ttgtgcaggt cggccatgcc ggcgccggtg agtgcgcgaa
    19501 ccaggttcat cgcggcgctg gcgttggcgt atgcacgcac cagtcgcgaa ggatcgtggg
    19561 cgcggactgc ctcgtcggcg acgagcgagt tgatcatgtc gccgcggtag gacttcagac
    19621 ccaacgagtc gatgtcggcc gagcgcggtt tggcgtactg gccggcgatg cgagcgacct
    19681 tgacgaccgg catcgaggaa ccgtaggtga gcacgacggc catctgcagc aacgtgcgga
    19741 tgtttccctt gatgtgcggc tcggtgttgt ccgcgaaggt ctcggcgcag tcaccgccct
    19801 ggagcagaaa tgcctcacca cgcgcgacct gcgcgagacg ctcttgcagc gcctcgactt
    19861 cgctggccac cgtgatggga ggcacgctct cgagcacagt ccgcatggcg gccgcctggt
    19921 cagcgggcca cgagggctgc tgagcagcgg gcttcgcgag cgcctcgtcg agctgcttac
    19981 gcagtccggc aggcagcggc gggagttcgg gcaagcggtc gatcggcacg tcgacagtcc
    20041 agttcacctc tacaggatat tcgctcgctc gtcggcgcgt cacacaggct ctcgatcgca
    20101 gcccaatcgg aacacttccc gcgcaccgaa acctgggtca gcgaagtgac cgtgcagccg
    20161 aaatggcgtc gaacttcacg aggttgtgcc tggcgtcggc aagtgcgtcg tgtgcgtcgg
    20221 cgggcgccga cgggagggca ggactgccgt tgtcttccca gaactgtcgg agttcgcggg
    20281 tgtaccgcgg catcgactgc ggtagttcgg tcatgtcgcc ccacaactgg cacagcgcga
    20341 cgtggtcgta ggcggcgacc cacgcccaga gctccggaac caccatcggc cgcggaacga
    20401 agaatttcag aagatcgtcg cggatcttct cgcgtgattt ccacagcggc gacgaaggct
    20461 gcggcaactt cggcagcacg ttcttgcgca cccaactacc ggcacgggcg ggatcgaact
    20521 ccgtcgaaac cgcgtagtac tctcggccgt cctcacagac aacgccgatg gacacgagat
    20581 cgatggttcg accgtcttcg atgaattcac agtcgtagaa gtagcgcacg tccgaaaact
    20641 atgccgcacg cgcaggctct ggagccaatg cgcgtgcggc cggtgtggga aatctctagc
    20701 tggcttgtgc gtccgggagc gaatccttgt cggacttcgc ggattccttc gactcggccg
    20761 aggccacgag atcgacaacc gactcgccgc cttccgccgg aacgtcgacg gcagcttcgg
    20821 gtttcgtggg cgcctggttc ttgaggcttg ccgcgtagat gtccacgtac tcctggccgg
    20881 agagtttcat caacttgtac atcacctcgt cggtcacagc gcgctcgacg aagcggtttc
    20941 cgcccatgcc ttcgaagcgg gagaaatcga tgggttcgcc gacgatcacg gtgaccttgg
    21001 cgggacgcca catccgtgag ccgatcggat tcatcttgtc ggtgccgacc atcgctaccg
    21061 ggatcacctt gacgcccgat tcaagtgcga ggcgcgccat tccggtcttg cccttgtaga
    21121 ggcgaccgtc aggcgagcgc gtcccctcgg ggtagatacc cagcaggctg cccgaaccga
    21181 ggaccttgag accggcgttg agtgcatcct gcgccgcgtc tgcaccggtt cggtcgatgg
    21241 ggacctgacc gaccgcggtg aagaaccact tctggaaagc gcccttcaga ccggaaccgg
    21301 tgaagtactc actcttggca aggaacgtga tgcggcggtt gacgcgaagc ggaaggtaga
    21361 acgagtccag aaccgcctgg tgattgctgg ccagaatggc cgccccgtca gtcggaatgt
    21421 tctcgtgacc cttgaccgtc ggacgcccga gcagccagag aatcggcccc agcaacacat
    21481 acttgaagag ccaataccac acggcgtccc tcccattcac agctgaattt cgctgagtac
    21541 gaccttactg ccgaccggta acccccgcta cacacgcccc tgcaggatcg acccgatcac
    21601 agtccggcag acgtggttcc agcgccgtcg accccaccga gatcctgagg cactaccgat
    21661 cgggccaaag cggcggcgcc gaccatgccc gcagcttcgc ccagctgagc ggaacggatg
    21721 cgggccagtg ggcggtgctt cgccccggtc aacaatgtcg cgtattgctc gcgggcgtcg
    21781 tcgagaaaca gtggggcaga actcgcgacg ccgccggcga tcacgaccag atcgggatcg
    21841 tagacgtcac cgaccatggc cagacccacg gccagccaac gggtgaactc ggcgatcgtt
    21901 gccagcgcga gtgggtcacc gtcctgcgcg gcgttggcga tccggcgacc ggtgagcgaa
    21961 ccaggatcca ccgctacctc acgcgccagg accgtcgacg cggccgggtc ggcggcaagc
    22021 agttcgattg ccgtgtcgac gagcgccgtt ccgctgcaat agcgctccca acacccacgt
    22081 ttgccacacg cgcactgacg cccgcccgga acgacctgga tgtggcccag ttcgggggcg
    22141 acgccgtgac tcccccggta cagctcaccg ttgatcagca gcgcaccacc gatgccggtc
    22201 ccgattgcca ccatcacgac attgcggcca cctgcggccg cgccgaatcg atgctccgcg
    22261 aaagccgccg cattggcgtc gtgttcgaga acgaccggca agccgagccg cttgctcaag
    22321 tcacttccga ccggcgcgtc cacccacggc aagtgcggag cgaaccgaac cgagcttcga
    22381 tcggaggtga tgaagccggc gaccgccaac cccacggccg atacctcgtg cctggtgacc
    22441 aattcgcgca cgacgcgatc gagaccgtct tcgagtgccc tggccgactg cggggtcggg
    22501 gcttgaatca tctcgagcac ttgtccgtcg acgtccacga cggaggccct gatactcgtc
    22561 ccgccgacgt cgatgccgac cgtcaagatg tcgtccatgg tggagtcgga gaccgctttc
    22621 aagcggcgcg cgctcatcac gacgattccc gcgcgagcgg cgtccgctgg agtgcgcacc
    22681 ctgaatcggt gcctcgtgcg tcggtgacca ttgtgtcgat tgtgctcatc tcgggccgtt
    22741 cgctctaccc ggggtactga gtcagtcctt gaccgtcacg ttgatcggga caaatgccgc
    22801 cgtgcgagtt cgctccgcac ctggcgtcgt cggaccgccg tccggtccac gatcgggacc
    22861 tgacggcccc ccgagaaact cgtcgagaat ctcacgaagc aacgcaagga atgcggctgc
    22921 ttgacccgcg aggaatgcca acagttcgtg gtgctcaccg cgaaccagtg cggcgagggc
    22981 gcacaccggg caccagctgc agccggtgaa caccggctgc gtgtccgtgg acgccgagtc
    23041 actcgcaacg tctgccgtcg ctgctgcggc cttctgcagc accggttcca ggcgcgtcag
    23101 aacggtttcc gccagcgcgc gaaactccgc gacgaggcgc tcgtgctctt cgctcatacc
    23161 ggccacaccg cgggatccgg gctgaaccgg atgatcaggt aactgccgtc caactccgcc
    23221 ccgttcacga cacaacgacg cagcaccgac gccaaacgaa ctctgcgtcg tacgccgtct
    23281 gctcccacca gcacatcgtc ctccacccgg cccaacgaca acgacgacgg atccacgagc
    23341 ggaaggtaca tccgcatcac gtacaccgaa tcgactccgg tcccggactc caacgacacc
    23401 acgatgttgt ccgcggtacc gacggtgccc gaatccgtgc ccgttccacc ctcgaacgtg
    23461 gccgcgatct cgcccagagc ggccaaccct accggttcgg cgcaagcgcg ttcgaccgtt
    23521 gtgacggaca ttccatcggt tgatccacgc agttcgtcca cgacgagtgc ctgagccgcc
    23581 cggatcgacg cgagccactg cgccgccggt gaatcgtcga cacccttccc ggcggacgag
    23641 ttgaactgcg ggacaaggtt gttgaccaca atcccgtcaa ctcgcaaccc ggccagagcc
    23701 agcccggaca acgtccgacg agtcgccgcg accgacacgc cgtcggccga cgtcaccaca
    23761 cgcacgccgg tgttctcccg atccgagagg tgaaccgcga tccgatccac cgacgcgagc
    23821 acgcgttcga cgacggacac gagcaggagc agccgcatgt ccgtacctgt cacagcgacc
    23881 atccgcctgt gccgcggcca caatcgctcg agatactccg acaccatcga cggcgagccg
    23941 agtatccgca gcgcttcggc tgcggccgga cagtccacga tcacgacgtc gtagtcgccg
    24001 ctgtccgaga ggtcgacgat ctcggcgagc ccgagcatgt cttggatgcc cagggatccc
    24061 gtcaactctt ccggttccaa gccctcgaac gacgaaccgt gttcgtgatc tcccgctccg
    24121 aaagttcctg cagcgtcgat caaccccgac aatcctcgga acttgtcctc gaggagcgct
    24181 gacgtgtcga gttgccggac gtcgagacgc tcggtgagag atgtggtcgt tcgcggattc
    24241 ggcacgccca ggacgtctgc aagagaacct gcctgatcga tcgacacgag cagcactctc
    24301 gccccatcgg tcgcagccga cacagcagtc gctgcggcaa gcgtcgtcgt gcctactccg
    24361 cctttaccga cgaacagttg gacgcgcgat cgttgctccg gcactcagcc ctcgactcgc
    24421 ttcttcagtt ccttcagagc tgtgtcggtg atgatcttct cggccttgcg cttgaacagt
    24481 ccgatcatcg gaatcgtcag gtcgaccgtc aactcatagg tgaccgacgt ggtgccgttc
    24541 gggccgggct cgagtgtgta cgaaccgaat tgggacttct gaatctcgcc cgagatcagc
    24601 tcccaactca ccgccatacc gtccggtgcc cacgaatact gcagttcgta ggtgtccttc
    24661 accatccccg cgtcgaggac gaaacgtact cggtccgcgc ggccgccctg tcccggcgcc
    24721 gtcacctcga cggacttcgc cgcggccacc cactcggggt accgctcgaa atcggcgatg
    24781 acgtccatca cggcgtcggc aggagcgtcg atgctgatca accccttggt cttctcggcc
    24841 atacgactgc gctaccttcc ttcgtcaaaa gtccagaacc tgcacaacgt gcagtgcttc
    24901 gattatcagt ccggtgctac tccggcggca cgtcccgctt cgagttcgcg tttgagctgg
    24961 aacgacatga ccttgccatc gacccgacgc ttgcggttca tcccggcgag gtcgagggtc
    25021 gccagatcgg acggcgatac gccgaccggc tcacagtgca ggaagtagtg cgcgatcgtc
    25081 ccgtccatgg ccggttcgag ccacacctcc atggtgccga ccagctgacc ggacactccc
    25141 caacggaatc ctgcgggacc gcgatcttcc cggacttcga gctcgagatc actgaaccag
    25201 cgacgccact gcgcgcgcga ggacaacagt tcggcgaccc gctcgggcgg ggcggcgatg
    25261 aaagtctggt ctgcgacctg aatgctgctc accgaagtag cttcacatat cgcgtccgcg
    25321 aagcgtcgag gggtgtcgca acactacata ccggacagac tgtaag
//
