MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
RGP42811.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002696.2 NRPS:Type I 99.0 100.0 1081.0 0.0
BAH33406.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000371.5 NRPS:Type I 98.0 100.0 1070.0 0.0
QRK05499.1 (2,3-dihydroxybenzoyl)adenylate_synthase BGC0002324.3 NRPS:Type I+PKS 60.0 95.5 635.0 1.23e-225
ABF86856.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002492.3 NRPS:Type I 60.0 95.3 632.0 9.33e-225
ABS75234.1 DhbE BGC0001185.5 NRPS:Type I 58.0 96.0 628.0 4.82e-223
AGK13425.1 enterobactin_synthetase_component_E_(2,3-dihydroxybenzoate-AMP_ligase) BGC0002528.3 NRPS:Type I 61.0 94.8 625.0 5.02e-222
AEI70243.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000401.5 NRPS:Type I 59.0 95.7 619.0 2.35e-219
AAZ55904.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000359.5 NRPS:Type I 60.0 96.2 618.0 3.21e-219
CAB15188.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000309.5 NRPS:Type I 58.0 96.4 618.0 3.95e-219
AAG31128.1 MxcE BGC0001345.5 NRPS:Type I 57.0 97.3 618.0 4.55e-219
CBA63660.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000368.5 NRPS:Type I 60.0 98.2 616.0 2.8e-218
NPC94428.1 (2,3-dihydroxybenzoyl)adenylate_synthase BGC0002695.2 NRPS:Type I 58.0 96.2 610.0 6.5e-216
QIE08740.1 salicylate-AMP_ligase BGC0002544.3 NRPS:Type I 57.0 95.1 583.0 1.33e-205
WP_068925906.1 AMP-binding_protein BGC0002688.2 NRPS:Type I 56.0 95.7 571.0 3.54e-201
AMK48234.1 salicylate-AMP_ligase BGC0001351.3 NRPS:Type I 56.0 95.3 570.0 2.97e-200
ACU36660.1 AMP-dependent_synthetase_and_ligase BGC0000392.5 NRPS:Type I 57.0 97.1 567.0 5.52e-199
WP_141576284.1 AMP-binding_protein BGC0002686.2 NRPS:Type I 57.0 95.3 563.0 5.2e-198
CAQ46282.1 putative_siderophore_specific_2,3-dihydroxybenzoate-AMP_ligase BGC0002689.2 NRPS:Type I 54.0 97.1 560.0 2.23e-196
MBD2892724.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002718.2 NRPS:Type I 54.0 97.5 549.0 3.52e-192
EFL06871.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000300.5 NRPS:Type I 55.0 95.3 545.0 5.38e-191
ABW70812.1 PchD BGC0002475.3 NRPS:Type I 52.0 95.8 537.0 3.21e-187
AAC45927.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002494.3 NRPS:Type I 53.0 96.2 536.0 6.06e-187
AAO07759.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000460.5 NRPS:Type I 52.0 96.0 530.0 2.42e-184
ABU70375.1 hypothetical_protein BGC0001890.3 NRPS:Type I 53.0 94.9 528.0 1.13e-183
AEF33098.1 3-hydroxypicolinic_acid:AMP_ligase BGC0001039.5 NRPS:Type I+PKS 50.0 97.5 524.0 2.97e-182
ctg4_1 BGC0002017.3 NRPS:Type I 56.0 87.4 515.0 2.15e-179
ALK21567.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002678.2 NRPS:Type I 53.0 96.6 517.0 2.81e-179
AGN74880.1 3-hydroxypicolinic_acid:AMP_ligase BGC0000459.5 NRPS:Type I+PKS:Trans-AT type I 51.0 95.7 512.0 1.31e-177
AGE11892.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000366.5 NRPS:Type I 49.0 99.1 501.0 1.09e-172
CAJ45636.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000454.5 NRPS:Type I 51.0 95.7 494.0 1.72e-170
CAC17498.1 putative_AMP-binding_ligase BGC0000324.5 NRPS:Type I 49.0 98.2 484.0 3.07e-166
MBE3202941.1 AMP-binding_protein BGC0002410.3 NRPS:Type I 46.0 102.9 485.0 3.66e-166
WP_005009579.1 AMP-binding_protein BGC0002473.3 NRPS:Type I 47.0 97.5 478.0 6.03e-164
ABL70475.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002493.3 NRPS:Type I 50.0 98.0 477.0 1.04e-163
BAC16758.1 probable_2,3-dihydroxybenzoate-AMP_ligase_protein BGC0002474.2 NRPS:Type I 48.0 96.0 475.0 4.33e-163
CCA53797.1 Long-chain-fatty-acid--CoA_ligase BGC0001801.5 NRPS:Type I 49.0 95.5 470.0 3.05e-161
EET76301.1 putative_(2,3-dihydroxybenzoyl)adenylate_synthase BGC0002685.2 NRPS:Type I 48.0 101.4 470.0 1.27e-160
KGA48878.1 (2,3-dihydroxybenzoyl)adenylate_synthase BGC0002413.3 NRPS:Type I 47.0 96.8 466.0 2e-159
AQZ26587.1 obafluorin_dimodular_nonribosomal_peptide_synthetase BGC0001437.5 NRPS:Type I 50.0 95.3 497.0 1.22e-158
ABK38474.1 2,3-dihydroxybenzoate-AMP_ligase BGC0001502.4 NRPS:Type I 48.0 98.0 464.0 1.53e-158
CAJ34366.1 putative_3-hydroxy-quinaldate-AMP-Ligase BGC0000445.5 NRPS:Type I 46.0 95.1 463.0 1.62e-158
AAQ59159.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002679.2 NRPS:Type I 48.0 96.0 463.0 1.7e-158
QYA95658.1 AMP-binding_protein BGC0002676.2 NRPS:Type I 47.0 96.8 463.0 3.12e-158
AFB35629.1 EsmD2 BGC0000935.5 other:aminocoumarin+PKS 46.0 96.4 459.0 1.55e-156
KDQ70107.1 Triostin_synthetase_I BGC0001444.5 other:shikimate-derived 46.0 96.4 458.0 3.17e-156
ACR11042.1 Enterobactin_synthetase_component_E/2,3-dihydroxybenzoate-AMP_ligase BGC0000451.5 NRPS:Type I 47.0 94.8 456.0 1.37e-155
CCP45172.1 Bifunctional_enzyme_MbtA:_salicyl-AMP_ligase_(SAL-AMP_ligase)_+_salicyl-S-ArCP_synthetase BGC0001021.5 NRPS:Type I+PKS 46.0 96.2 456.0 2.33e-155
MBX9445642.1 (2,3-dihydroxybenzoyl)adenylate_synthase BGC0002414.3 NRPS:Type I 48.0 98.2 455.0 3.14e-155
ALE27504.1 3-HPA:AMP_ligase BGC0001292.5 other:other 45.0 97.7 450.0 7.01e-153
AAC73695.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002476.2 NRPS:Type I 46.0 96.6 448.0 1.89e-152
BAC87906.1 probable_acinetobactin_biosynthesis_protein BGC0000294.5 NRPS:Type I 44.0 98.4 446.0 1.84e-151
AVR52609.1 AMP-dependent_synthetase BGC0002443.3 PKS 46.0 96.9 444.0 8.67e-151
EYT83445.1 Triostin_synthetase_I BGC0001213.5 PKS 43.0 95.8 441.0 1.07e-149
KJY85277.1 enterobactin_synthase_subunit_E BGC0002491.3 NRPS:Type I 46.0 98.0 439.0 8.67e-149
AAO56101.1 yersiniabactin_synthetase,_salicylate_ligase_component BGC0002570.2 NRPS:Type I+PKS 47.0 92.2 437.0 1.41e-148
BAH04171.1 AMP-binding_ligase BGC0000450.5 NRPS:Type I 46.0 95.1 437.0 1.65e-148
ACY02013.1 enterobactin_synthase_subunit_E BGC0000343.5 NRPS:Type I 46.0 96.9 437.0 2.6e-148
BAI63284.1 putative_peptide_arylation_enzyme BGC0000434.5 NRPS:Type I 46.0 94.9 437.0 3.42e-148
ADB92576.1 Ccb2 BGC0001225.5 NRPS:Type I 45.0 98.2 437.0 6.51e-148
ADE34495.1 SsfL1 BGC0000269.5 PKS:Type II+saccharide:hybrid/tailoring 46.0 97.7 431.0 1.01e-145
AAK95837.1 putative_2,3-dihydroxybenzoate-AMP-ligase_PhbE BGC0002495.2 NRPS:Type I 46.0 96.9 431.0 1.14e-145
CAJ87594.1 2,3-dihydroxybenzoate-AMP_ligase BGC0001055.5 NRPS:Type I+PKS 49.0 89.7 428.0 9.05e-145
BAE98151.1 putative_AMP-binding_ligase BGC0000339.5 NRPS:Type I 44.0 95.3 426.0 5.46e-144
CAA73130.1 Irp5_protein BGC0000467.5 NRPS:Type I 48.0 89.7 426.0 7.25e-144
AET98914.1 putative_AMP-binding_ligase BGC0000415.5 NRPS:Type I 45.0 95.1 423.0 8.75e-143
ABY66018.1 CoA_ligase BGC0001008.5 PKS:Iterative type I 46.0 96.8 421.0 6.83e-142
CCC55917.1 putative_acyl_CoA_ligase BGC0000973.5 NRPS:Type I+PKS:Type I 46.0 96.2 421.0 1.5e-141
WP_069848012.1 salicylate_synthase BGC0002472.2 NRPS:Type I 44.0 94.6 432.0 5.7e-141
AXG47413.1 salicylate_synthase BGC0002715.2 NRPS:Type I+PKS 48.0 86.3 429.0 9.89e-140
ATV95617.1 CoA_ligase BGC0001503.4 PKS 45.0 97.7 414.0 5.57e-139
AEM06018.2 hypothetical_protein BGC0000966.5 NRPS:Type I+PKS 44.0 97.8 412.0 2.16e-138
AFD30957.1 CrmE BGC0000966.5 NRPS:Type I+PKS 44.0 97.8 412.0 6.16e-137
AAM77987.1 adenylate_ligase BGC0000112.5 PKS:Iterative type I 43.0 97.5 404.0 3.83e-135
ACN64830.1 PokM3 BGC0001061.4 PKS:Type II aromatic 44.0 97.5 403.0 8.71e-135
AFV52187.1 acyl-CoA_synthetase BGC0000081.5 NRPS:Type I+PKS:Iterative type I 44.0 99.5 390.0 1.14e-129
AAO07763.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000460.5 NRPS:Type I 41.0 94.2 373.0 4.69e-123
MBN3579117.1 AMP-binding_protein BGC0002613.2 NRPS:Type I+PKS 40.0 97.3 368.0 2.38e-121
CAG69514.1 2,3-dihydroxybenzoate-AMP_ligase BGC0000352.5 NRPS:Type I 40.0 96.2 366.0 1.51e-120
AKQ52536.1 2,3-dihydroxybenzoate-AMP_ligase BGC0002533.2 NRPS:Type I+PKS 40.0 96.9 365.0 2.43e-120
ADQ74621.1 salicylyl-AMP_ligase BGC0000921.5 other:shikimate-derived+PKS+NRPS:Type I 41.0 95.1 360.0 1.69e-118
CAP20363.1 equibactin_siderophore_biosynthetic_protein BGC0000347.5 NRPS:Type I 38.0 93.1 356.0 8.17e-117
KZM73517.1 hypothetical_protein BGC0000632.5 terpene+saccharide 40.0 89.9 306.0 4.57e-97
BAO66547.1 cyclohexanecarboxylate-CoA_ligase BGC0000042.5 PKS 31.0 91.5 201.0 2.54e-57
AHH25585.1 AMP-dependent_synthetase_and_ligase BGC0000957.5 NRPS:Type I+PKS 31.0 96.2 203.0 4.78e-56
MBE3200457.1 AMP-binding_protein BGC0002409.3 NRPS:Type I 34.0 95.1 193.0 1.6e-54
ADI58632.1 AsuB1 BGC0000187.5 PKS:Type II 32.0 94.9 194.0 8.11e-53
AWX24488.1 acyl-CoA_ligase BGC0001695.5 NRPS:Type I 33.0 88.3 186.0 2.3e-52
AAQ84158.1 PlmJK BGC0000123.5 PKS 30.0 102.0 188.0 8.15e-51
BBD17745.1 AMP-ligase BGC0001918.3 NRPS:Type I+PKS 30.0 87.2 175.0 2.74e-48
WP_240809958.1 long-chain_fatty_acid--CoA_ligase BGC0002686.2 NRPS:Type I 33.0 92.8 174.0 1.28e-47
ABU70356.1 hypothetical_protein BGC0001890.3 NRPS:Type I 29.0 94.0 156.0 3.6e-41
MBD2892711.1 3-methylmercaptopropionyl-CoA_ligase BGC0002718.2 NRPS:Type I 31.0 92.4 155.0 1.09e-40
OJF16272.1 AceP1 BGC0001491.3 PKS 30.0 97.1 153.0 6.44e-39
QIC03945.1 EncH BGC0002366.2 PKS 29.0 99.6 147.0 4.77e-38
CAO85890.1 aryl-coA_ligase BGC0000110.5 PKS:Type I 31.0 94.2 148.0 8.24e-38
AAF81723.1 putative_acyl-CoA_ligase_EncH BGC0000220.4 PKS:Type II 29.0 95.5 145.0 3.08e-37
QIZ24104.1 type_I_polyketide_synthase BGC0002540.3 PKS 29.0 94.8 148.0 4.02e-37
CRI73800.1 loading_module_of_NRPS-PKS BGC0001215.5 NRPS:Type I 31.0 94.8 134.0 1.67e-32
CAE17553.1 acyl_CoA_ligase BGC0000210.5 PKS:Type II+saccharide:oligosaccharide 27.0 92.2 125.0 3.06e-30
NP_626687.1 acyl-CoA_synthetase BGC0000595.3 ribosomal:unmodified 29.0 90.3 120.0 7.54e-29
QQZ01622.1 amide_synthase BGC0002497.3 other:other 30.0 71.8 120.0 1.32e-28
CAN89633.1 putative_hybrid_non-ribosomal_peptide_synthetase/polyketide_synthase BGC0001070.5 NRPS:Type I+PKS:Type I 28.0 92.2 116.0 1.06e-26
BCK51658.1 putative_acyl-CoA_synthetase BGC0002520.2 PKS 28.0 93.1 111.0 6.35e-26
BBD17741.1 non-ribosomal_peptide_synthetase BGC0001918.3 NRPS:Type I+PKS 27.0 99.6 112.0 2.26e-25
CAG29031.1 nonribosomal_peptide_synthetase_(modules_1_and_2) BGC0001023.5 NRPS:Type I+PKS:Type I 26.0 92.4 111.0 3.81e-25
APZ78821.1 nonribosomal_peptide_synthetase BGC0001429.4 NRPS:Type I+PKS:Iterative type I 26.0 92.4 111.0 3.81e-25
SSTG_01180 BGC0000597.4 ribosomal:RiPP:Proteusin 30.0 78.3 108.0 5.3e-25
EPE34349.1 Acetyl-CoA_synthetase-like_protein BGC0001035.5 PKS+NRPS:Type I 25.0 88.6 108.0 1.27e-24
QIW91880.1 Ligase BGC0002543.3 NRPS:Type I 29.0 66.4 107.0 2.33e-24
APZ78833.1 nonribosomal_peptide_synthetase BGC0001430.4 NRPS:Type I+PKS:Iterative type I 27.0 95.7 107.0 8.63e-24
BAQ25518.1 acyl-CoA_synthetase BGC0001288.5 PKS 28.0 88.6 105.0 9.13e-24
AGM05527.1 AMP-dependent_synthetase_and_ligase BGC0002098.2 PKS 26.0 90.8 105.0 1.02e-23
APZ78845.1 nonribosomal_peptide_synthetase BGC0001431.4 NRPS:Type I+PKS:Iterative type I 27.0 92.8 107.0 1.14e-23
APZ78679.1 nonribosomal_peptide_synthetase BGC0001417.4 NRPS:Type I+PKS:Iterative type I 27.0 92.8 106.0 1.52e-23
AAC06346.1 bacitracin_synthetase_1 BGC0000310.5 NRPS:Type I 24.0 94.4 105.0 3.76e-23
CBF76048.1 conserved_hypothetical_protein BGC0001399.4 NRPS:Type I 27.0 91.9 102.0 1.01e-22
AFK57213.1 DidB BGC0000985.5 NRPS:Type I+PKS 28.0 103.1 103.0 1.74e-22
AFK57217.1 DidF BGC0000985.5 NRPS:Type I+PKS 27.0 95.1 102.0 2.24e-22
APZ78855.1 nonribosomal_peptide_synthetase BGC0001432.4 NRPS:Type I+PKS:Iterative type I 26.0 92.8 102.0 2.56e-22
ATY69551.1 hybrid_nonribosomal_peptide_synthetase/type_I_polyketide_synthase BGC0001611.4 PKS:Type I 27.0 94.4 101.0 7.56e-22
QOV09194.1 ClyF/NocQ BGC0002597.2 NRPS:Type I+PKS 26.0 104.2 100.0 1e-21
CAE15497.1 BGC0002286.3 NRPS:Type I 26.0 88.3 100.0 1.47e-21
AQX77695.1 NocQ BGC0001704.3 other:other 26.0 91.3 100.0 1.76e-21
QBA57736.1 NRPS BGC0002377.2 NRPS:Type I 28.0 95.8 99.0 3.14e-21
AKL71650.1 NocQ BGC0001703.3 other:other 24.0 103.4 99.0 5.41e-21
AAF99707.2 syringopeptin_synthetase BGC0000438.5 NRPS:Type I 27.0 96.8 98.0 7.92e-21
MBC5793737.1 non-ribosomal_peptide_synthetase_(depsipeptide_synthetase) BGC0002480.2 PKS+NRPS:Type I 25.0 100.5 97.0 1.66e-20
AYM52861.1 AMP-binding_protein BGC0001964.2 PKS 26.0 97.7 96.0 1.74e-20
ABF92798.1 AMP-binding_protein BGC0001831.3 PKS 26.0 97.1 93.0 1.3e-19
ALG65318.1 Cal18 BGC0001297.4 NRPS:Type I 28.0 95.1 93.0 3.68e-19
AVR48535.1 CusC BGC0001564.4 NRPS:Type I+PKS 23.0 94.0 92.0 5.42e-19
MCC5036796.1 AMP-binding_protein BGC0002638.3 NRPS:Type I 29.0 63.4 87.0 5.7e-18
AKP45400.1 CysL BGC0001413.5 NRPS:Type I 25.0 89.4 87.0 1.41e-17
BAK64635.1 putative_CoA_ligase BGC0000135.5 PKS 27.0 94.0 82.0 6.07e-16
BCK51655.1 Adenylate-forming_enzyme BGC0002520.2 PKS 29.0 64.1 81.0 9.78e-16
BBC83957.1 nonribosomal_peptide_synthetase BGC0001636.4 NRPS:Type I 24.0 93.3 82.0 9.86e-16
AQW35047.1 Acyl-CoA_synthetase BGC0001675.5 PKS 27.0 98.2 81.0 1.06e-15
EJP62835.1 nonribosomal_peptide_synthase,_putative BGC0002203.2 NRPS:Type I+PKS+other:other 24.0 85.4 76.0 1.03e-13
CBW54660.1 Acyl-CoA_ligase BGC0000971.5 NRPS:Type I+PKS:Type I 26.0 100.5 74.0 2.25e-13
CAJ88192.1 putative_peptide_synthetase_NRPS5-4-3 BGC0000151.5 PKS:Type I+saccharide:hybrid/tailoring 28.0 106.0 70.0 2.8e-12
AFO59871.1 ChxJ BGC0000175.5 PKS:Trans-AT type I 29.0 62.5 71.0 2.98e-12
AMQ36134.1 PsyC BGC0002617.2 NRPS:Type I 23.0 94.8 64.0 4.29e-10
QCF28941.1 fatty_acyl-AMP_ligase BGC0002308.2 other:other+PKS 26.0 105.4 62.0 1.28e-09
AZY91992.1 putative_fatty_acyl-AMP_ligase BGC0002022.4 PKS 26.0 89.2 58.0 2.07e-08