LOCUS       NZ_JARBUT010000020     21086 bp    DNA     linear   CON 29-APR-2024
DEFINITION  Nocardiopsis sp. N85 Scaffold20, whole genome shotgun sequence.
ACCESSION   NZ_JARBUT010000020
VERSION     NZ_JARBUT010000020.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardiopsis sp. N85
  ORGANISM  Nocardiopsis sp. N85
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Nocardiopsaceae; Nocardiopsis.
REFERENCE   1  (bases 1 to 118812)
  AUTHORS   Liu,S.
  TITLE     Nocardiopsis sp. N85
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 118812)
  AUTHORS   Liu,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2023) Microbial Chemistry, Institute of Medicinal
            Biotechnology, Chinese Academy of Medical Sciences, Tiantanxili No.
            1, Beijing 100050, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 1.05
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 182.0x
            Sequencing Technology :: combinatorial probe-anchor synthesis
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028882275.1-RS_2024_04_29
            Annotation Date                   :: 04/29/2024 06:01:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,729
            CDSs (total)                      :: 5,663
            Genes (coding)                    :: 5,611
            CDSs (with protein)               :: 5,611
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 9 of 53
            Pseudo Genes (incomplete)         :: 46 of 53
            Pseudo Genes (internal stop)      :: 0 of 53
            Pseudo Genes (multiple problems)  :: 3 of 53
            CRISPR Arrays                     :: 13
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:47:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 32099
            Orig. end                         :: 53185
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JARBUT010000020.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11086)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(190..205)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     misc_feature    256..267
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    278..292
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.37"
                     /tool="antismash"
     gene            complement(370..2349)
                     /gene="pknB"
                     /locus_tag="PWG71_RS23000"
                     /old_locus_tag="PWG71_23000"
     CDS             complement(370..2349)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014911144.1"
                     /locus_tag="PWG71_RS23000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23000"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_274812024.1"
                     /sec_met_domain="Pkinase (E-value: 1.5e-52, bitscore:
                     171.2, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 6.6e-08, bitscore: 25.4,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDMTTSDPLVGATLDQRYFVESRIAGGGMATVYVAHDLRLDRRLA
                     LKVMHPSLAQDPTFVQRFINEAHSVAKLSHPNVVQVFDQGEDRGHVFLAMEYVPGRTLR
                     ALLKERGRLSARDALQVMAPVLAALGAAHRAGMVHRDIKPENVLITEDGRIKVADFGLA
                     RAVEQSTQGLTRTGTLMGTAAYLAPEQIERGTADARTDVYAAGIMFYELLTGSQPHTGE
                     TPIAIAYQHVNEDVPRPSHFLPGLPAEVDALVTKATERDPRYRPGNAGQYLSKVLEVLR
                     HLPETPQVKGAPLPPVAPVAATTAAVTAPQLIAGGAGPGTENATMIVEMGGPADDGYDD
                     YDDDHFDEGPDRRRRATLMAVGATVLALVVFVAGWWFLVGRFESVPEIIGAEQEAACAA
                     LRDTGLKCEVAEEGVYSSEAAGTVGKVEPNVGERLSPGDTVTIQLSKGPREVEMPDFKG
                     QDVSNAIKEMETLGFDPESLLQEVVDAENVQPGEVISTDPAPGEEADRESTVTFTVSRG
                     IDVPALTGQGVDDARNALEELGLTVKIVEAESESVDDGLVISQKPDTGTTLSAGGEVEL
                     TVSTGPPGVEIPDVVGRNVKEAREMLEDAGFEVKVERFLGGRTVAEQSHTGKAPEGTEI
                     TIIATPVGLPLGELELDEDDDDDD"
     gene            complement(2831..3601)
                     /locus_tag="PWG71_RS23005"
                     /old_locus_tag="PWG71_23005"
     CDS             complement(2831..3601)
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017617057.1"
                     /locus_tag="PWG71_RS23005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23005"
                     /product="thiazole synthase"
                     /protein_id="WP_274812025.1"
                     /transl_table=11
                     /translation="MNAHTDDPLVISGVSFGSRLITGTGGAPSLEVLEEALIASGTELT
                     TVAMRRVAPGARGSVWEVLERNGIRPLPNTAGCFTATDAVRTARLGREALGTGWVKLEV
                     VADEHTLLPDPVELLEAAERLVDEGFAVLPYTNDDPVLARRLEQIGCVAVMPLAAPIGS
                     GLGIRNPHNLELIVEQAGVPVIVDAGIGTASDAALAMELGCDAVLLASAVTRAEDPVLM
                     AGAMRDAVRAGRAARRAGRIPVRRHARASSPAVD"
     gene            complement(3604..3819)
                     /gene="thiS"
                     /locus_tag="PWG71_RS23010"
                     /old_locus_tag="PWG71_23010"
     CDS             complement(3604..3819)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017565075.1"
                     /locus_tag="PWG71_RS23010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23010"
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_274812098.1"
                     /transl_table=11
                     /translation="MELIVNGALREAAGTVTVEEIVRELTAADGGAIPGGIAVAVNDEV
                     VRRAAWAGTPLGAGDRVDVLTAVQGG"
     gene            complement(3825..5087)
                     /gene="thiO"
                     /locus_tag="PWG71_RS23015"
                     /old_locus_tag="PWG71_23015"
     CDS             complement(3825..5087)
                     /EC_number="1.4.3.19"
                     /GO_function="GO:0016647 - oxidoreductase activity, acting
                     on the CH-NH group of donors, oxygen as acceptor [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="thiO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014911304.1"
                     /locus_tag="PWG71_RS23015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23015"
                     /product="glycine oxidase ThiO"
                     /protein_id="WP_274812026.1"
                     /sec_met_domain="DAO (E-value: 3.7e-63, bitscore: 206.9,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAKGVESSTVPTSNPPHPDTIHPTSEPSEDRHGVIVVGGGLVGR
                     VTAWRAAQAGLRVTLIEPDPVTDPAGARAASTVAAGMLTPATEAVFGEEHLMGFGIRSA
                     ALYPAFVAELEEASGVPTGHHATGTLLVAFDRDDLAVLDRLHDLQKRLGVTTERLTGRE
                     CRRLEPMLAPSVRGGVLAPEDHSVDPRLLLRALAVAGDRAGVTEIRSRAIAVERPGPGG
                     ARLGVTPAEGRTLPADQVVLAAGCWSDRIELPEPVVPPLRPVKGQLLRARVPAGEPPLV
                     ERTVRGLVRGFPVYLVPRADGEIVIGATQEELGYDTAPTVGGLWQVLRDARELVPGVTE
                     LEITETCVGLRPGSPDNEPLLGPTRVPGLHLAGGHFRHGVLLTPVTGEVMAHALTTGTL
                     PGYARRFTADRVTGGETTTWK"
     regulatory      complement(5055..5166)
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    5086..5099
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            5282..5641
                     /locus_tag="PWG71_RS23020"
                     /old_locus_tag="PWG71_23020"
     CDS             5282..5641
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017605963.1"
                     /locus_tag="PWG71_RS23020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23020"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_274812027.1"
                     /transl_table=11
                     /translation="MTSSDSNLDTLVGTWLTLRETASPLGVSPNHVKTLIRENRLMGVV
                     RGGQLSVPAAFIDGGDIVKGLPGTLVLLGDAGYSTEEALRWLFTPDDTLPGTPIQAMRE
                     NRGTEVRRRAQSLAF"
     gene            5716..6381
                     /gene="thiE"
                     /locus_tag="PWG71_RS23025"
                     /old_locus_tag="PWG71_23025"
     CDS             5716..6381
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017609707.1"
                     /locus_tag="PWG71_RS23025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23025"
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_274812028.1"
                     /transl_table=11
                     /translation="MRTSHGTSLRKRLDASLLYLCTDARRERGDLAEFAEAALSGGVDI
                     VQLRDKGLEAREEIAALEVLREACERHGALLAVNDRADIARAVRADVLHLGRRDLPVPM
                     ARDIIGADPLIGRSNNDIDAARASAEEPGSDYFCVGPVWETPTKPGRPAAGTELVERAA
                     ALNSDRPWFAIGGIDLDTVDRVLDAGARRVVVVRAITEAEDPRAAAAALRARVIDRQG"
     gene            complement(6495..7493)
                     /locus_tag="PWG71_RS23030"
                     /old_locus_tag="PWG71_23030"
     CDS             complement(6495..7493)
                     /NRPS_PKS="Domain: PKS_ER (16-330). E-value: 2.2e-34.
                     Score: 110.9. Matches aSDomain:
                     nrpspksdomains_PWG71_RS23030_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017565071.1"
                     /locus_tag="PWG71_RS23030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23030"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_274812029.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.8e-24, bitscore:
                     77.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVRVDGFGGPEVLTAREVPDPEVGPGSVEVTVDAANVMYLEVL
                     VRSGWGRDFFPVTPPYVPGTGVVGTVSRVGEGVDPSWVGTRVVTDTGERTADGSALPVG
                     GYAERAVVPESDLIRVPEGVDPHHALALLHDGPTALALARTADYRPGQTVLVAAATGGA
                     GSLSVQLARNAGARVIAAARGGDKLALAEKLGAHEVVDYSLPGWTDRVLELTGGIGVDT
                     ALDGAGASLGEEAFTTVARGGRFVGYGSAGGRFAEIEPARALEHEVEVFGLFDIKDEAE
                     ARTRALGEALELVRSGRLTPHIGLTLPLEDAAEAHRAMEERRVLGKVLLIP"
     aSDomain        complement(6504..7445)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PWG71_RS23030_PKS_ER.1"
                     /evalue="2.20E-34"
                     /label="PWG71_RS23030_PKS_ER.1"
                     /locus_tag="PWG71_RS23030"
                     /protein_end="330"
                     /protein_start="16"
                     /score="110.9"
                     /tool="antismash"
                     /translation="AREVPDPEVGPGSVEVTVDAANVMYLEVLVRSGWGRDFFPVTPPY
                     VPGTGVVGTVSRVGEGVDPSWVGTRVVTDTGERTADGSALPVGGYAERAVVPESDLIRV
                     PEGVDPHHALALLHDGPTALALARTADYRPGQTVLVAAATGGAGSLSVQLARNAGARVI
                     AAARGGDKLALAEKLGAHEVVDYSLPGWTDRVLELTGGIGVDTALDGAGASLGEEAFTT
                     VARGGRFVGYGSAGGRFAEIEPARALEHEVEVFGLFDIKDEAEARTRALGEALELVRSG
                     RLTPHIGLTLPLEDAAEAHRAMEERRVLGKVLL"
     CDS_motif       complement(6981..7043)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PWG71_RS23030_0001"
                     /evalue="1.40E-04"
                     /label="PKSI-ER_m5"
                     /locus_tag="PWG71_RS23030"
                     /protein_end="171"
                     /protein_start="150"
                     /score="14.5"
                     /tool="antismash"
                     /translation="GQTVLVAAATGGAGSLSVQLA"
     misc_feature    complement(7581..7596)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.78"
                     /tool="antismash"
     misc_feature    7583..7597
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.11"
                     /tool="antismash"
     gene            complement(7618..8511)
                     /locus_tag="PWG71_RS23035"
                     /old_locus_tag="PWG71_23035"
     CDS             complement(7618..8511)
                     /EC_number="1.6.5.2"
                     /GO_function="GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013154128.1"
                     /locus_tag="PWG71_RS23035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23035"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_274812030.1"
                     /transl_table=11
                     /translation="MGDDHMTNHTIGVTGATGAVGGRVAARIARLGRAQRLIVRDLNRA
                     PDHPGSTAAMAAYEDTANFARACRGVDTLFLVPATESEDRIDTHLSAVDAAVAAGVSRI
                     VYLSFLQAGPASTFTFARTHFFTEAHIRTTGVRYTFLRPSLYLDLLPHWVDESGVVRGP
                     AGEGRVAWVARDDIADVVAAVLTDPALAAAAENATYDVTGPEALSLGATVERLSALTGR
                     TIRYVPETREEALLSRKATGAPEWEIEGWVSSYEAIAAGELDEVAATVQKVTGHPARSI
                     EGFLRRHPSALSHVSV"
     gene            complement(8580..9860)
                     /locus_tag="PWG71_RS23040"
                     /old_locus_tag="PWG71_23040"
     CDS             complement(8580..9860)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014911926.1"
                     /locus_tag="PWG71_RS23040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23040"
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_274812031.1"
                     /transl_table=11
                     /translation="MSRNAVARGPAGAGERALAPDLARGFMLLFIALANTVWYLWTVPM
                     GELGAHPAPESTLDSVTQFFTIMVVDGRSYPMFAFLFGYGMVQLAMRQEAAGASVKDVN
                     ALLRRRNLWLLAFGFFHALLLWFGDVLGAYGLAGLLLGWLFLRRKDTTLLVWASVFIGL
                     LAALTAFSVVGMVLAPDGPSSGTGMDAMAASAAETSILGAALGRVIVWPLITVVQGLVA
                     LVVPTMILLAFWAARRRVLEEPGSHLPLLRWTAGLGIAIGWLGGLPNALAQVGVWEPNP
                     TQASMLAMPHMLAGLFGGLGYVALIALIAHAIQGRGREPGVVLTAITATGKRSLSSYLA
                     QSVLCAPILTAWGLGLAAYLTSWTMFLYAIGVWLITVVAAYLMERAGVRGPAEVLLRRL
                     AYRHSTREPVPVGTVPPEGEDQERATP"
     misc_feature    9883..9896
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.34"
                     /tool="antismash"
     gene            complement(10001..11086)
                     /locus_tag="PWG71_RS23045"
                     /old_locus_tag="PWG71_23045"
     CDS             complement(10001..11086)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017599998.1"
                     /locus_tag="PWG71_RS23045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23045"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_274812032.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.8e-44, bitscore:
                     144.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAFSSSSSLSPVSAIRSDVDRELDAFCADHRLTLLEVGEELAPA
                     MDALEAMLTGGKRLRPAFCYQGWRGAGGAADDERIVRAAASLEFLQACALIHDDVIDNS
                     DTRRGLPATHKRLAGLHAERGWSGDGEGFGRGAAVLIGDLCLAWSDEMYQASGFAQDTL
                     AWGRRPFDAMRTEVMAGQYLDTLEQVRGTGTREAALRVMRYKSAKYTVERPLHLGAALA
                     GRLPELEGVYTAYGIPLGVAFQLRDDVLGVFGDPSTTGKPAGDDLREGKRTLVVAETLA
                     RSDAADGARFTALLGAPDLSVGSVEWMCGLIESSGALAACEELVERYSEEALAALESPE
                     LDDAAREPLRTMVAVATRRTH"
     misc_feature    11069..11085
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.86"
                     /tool="antismash"
     gene            complement(11105..11881)
                     /locus_tag="PWG71_RS23050"
                     /old_locus_tag="PWG71_23050"
     CDS             complement(11105..11881)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017565067.1"
                     /locus_tag="PWG71_RS23050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23050"
                     /product="DUF817 domain-containing protein"
                     /protein_id="WP_274812033.1"
                     /transl_table=11
                     /translation="MTFFFAQLTRFGLLQARACAFAACMFAGFALSMAVPLPIARYDAL
                     LIYAVAVTALFWALRLETGREIAAIAGFHVVGLAFELFKVRMGSWSYPGPGWTVVWGVP
                     LYSGFMYAAVGSYIVRAWRLFDLGLTNYRSWAVTAVAIAIYANFLTHHWLPDLRIPLAV
                     LLIAVTWGTWVHFTVGEQRPRLPLALSFLFIGFFLWVAENISTLFDAWRYPHQAEVWAL
                     VHPAKLGAWALLVTVSFVLVAMWKGPGARKGAGPSG"
     gene            12112..12954
                     /gene="metF"
                     /locus_tag="PWG71_RS23055"
                     /old_locus_tag="PWG71_23055"
     CDS             12112..12954
                     /EC_number="1.5.1.20"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017576793.1"
                     /locus_tag="PWG71_RS23055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23055"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_274812099.1"
                     /transl_table=11
                     /translation="MFSFEFFPPRSPQANERLWRAIRQLEALGPAFVSVTYGAGGSTRG
                     MTVETTERIATDTTLLPVAHMTLVEHSVAELRHLIGRLADAGVSNMLAVRGDPPGDPSG
                     PWVSHPEGLTYAEELVRLIKDSGDFCVGVAAFPYKHPRSADVETDTDFFVRKCDAGADY
                     AITQMFFDPEDYLRLRDRVAARGCDIPIIPEVFPVVRTSFIPRSEKLSGAPFPADLAAR
                     FESFGDDTEAVRAFGIEHAQHMCERLLEEGAPGIHFITSNQSTATREIYREVSGRRRP"
     gene            complement(12887..13501)
                     /locus_tag="PWG71_RS23060"
                     /old_locus_tag="PWG71_23060"
     CDS             complement(12887..13501)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017576792.1"
                     /locus_tag="PWG71_RS23060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23060"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_274812034.1"
                     /transl_table=11
                     /translation="MVADVELRELGPPAFAHAVPALLQVYEAAMEPPPEQLPGRASVMK
                     THSRHPGFRSIVAVLEERPIGFAYAFHGARGQWWHDTVSAGLRAEGGRAGARRWMTDAF
                     EIAEVHVHPEAQNRGIGRAVLHALCSDRPERTAILSTRAGPTAARHLYRSCGFVEVLEE
                     FSFPGSPDRPFSIMATRLPLTGAVVPTPPGRSPWWRWTDSR"
     misc_feature    complement(13643..13658)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.93"
                     /tool="antismash"
     misc_feature    13644..13657
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 22.33"
                     /tool="antismash"
     misc_feature    complement(13644..13658)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.29"
                     /tool="antismash"
     gene            complement(13839..14333)
                     /locus_tag="PWG71_RS23065"
                     /old_locus_tag="PWG71_23065"
     CDS             complement(13839..14333)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622275.1"
                     /locus_tag="PWG71_RS23065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23065"
                     /product="transcriptional regulator"
                     /protein_id="WP_073384121.1"
                     /transl_table=11
                     /translation="MPSEYAKSLGARLRAIRTQQGLSLHGVEEKSHGRWKAVVVGSYER
                     GDRAVTVQKLAELADFYGVPMSELLPGGAAPTPLGPTPKLVIDLERMQQLPQEKAGPLS
                     RYVATIQSQRGDYNGRVLSIRQEDLRSLAVIYDKSPGDLTEELINWGVLDPEARRAVDS
                     F"
     misc_feature    complement(14606..14624)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.97"
                     /tool="antismash"
     misc_feature    complement(14633..14649)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 19.95"
                     /tool="antismash"
     misc_feature    complement(14697..14712)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            14885..15517
                     /gene="pyrR"
                     /locus_tag="PWG71_RS23070"
                     /old_locus_tag="PWG71_23070"
     CDS             14885..15517
                     /EC_number="2.4.2.9"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017605971.1"
                     /locus_tag="PWG71_RS23070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23070"
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="WP_274812100.1"
                     /transl_table=11
                     /translation="MPEGTRAVLDGNEINRALTRIAHEVLERTKGGHGVTLLGIPSRGV
                     PLAARLAERIEHVEKLAVPHGSLDITMYRDDLRTAPPRALGRTEIPDGGLDDRVVVLVD
                     DVLFSGRTVRAALDALNDLGRPRAVQLAVLVDRGHRQLPIRADYVGKNLPTSLRESVTV
                     RLTETDGHDAVLLGPSRPSSSATLTGGPLPGALGRRPDTDGTEGKDS"
     gene            15517..16425
                     /locus_tag="PWG71_RS23075"
                     /old_locus_tag="PWG71_23075"
     CDS             15517..16425
                     /EC_number="2.1.3.2"
                     /GO_function="GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0016597 - amino acid binding [Evidence
                     IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1114: ornithine carbamoyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014913461.1"
                     /locus_tag="PWG71_RS23075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23075"
                     /product="aspartate carbamoyltransferase catalytic subunit"
                     /protein_id="WP_274812035.1"
                     /transl_table=11
                     /translation="MRHLLSTGDLTRDEAVLILDTAAELARVGDRSVKKLPTLRGRTVV
                     NLFYEDSTRTRTSFELAAKRLSADVVNFSAKGSSVSKGESLKDTALTLQAMGADGVVIR
                     HSASGAAHRLANWVDGSVLNAGDGTHEHPTQALLDAYTMRARLGRLEGLRVAIVGDILH
                     SRVARSNVLLLTTLGAHVTLVAPPTLLPVSVRTWPCEVSYDLDEVLPKADVVMMLRVQA
                     ERMHASFFPSVREYSRGYGIDGARLSRMPEDAIVMHPGPMVRGMEISAEVADSPRCTVV
                     EQVANGVSLRMAVLYLLLGGS"
     misc_feature    complement(16486..16502)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.66"
                     /tool="antismash"
     gene            16529..17830
                     /locus_tag="PWG71_RS23080"
                     /old_locus_tag="PWG71_23080"
     CDS             16529..17830
                     /EC_number="3.5.2.3"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017565062.1"
                     /locus_tag="PWG71_RS23080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23080"
                     /product="dihydroorotase"
                     /protein_id="WP_274812036.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 8.8e-18, bitscore:
                     57.3, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDNHGPHLIRGARPLGADPADILIVDGRIAEIGTDLRAPEGTEV
                     VDGTGLIALPGLVDLHTHLREPGREDAETVETGSHSAAMGGYTAVHAMANTDPVADTAG
                     VVEQVWRLGREAGYCDVRPVGAVTVGLAGERLSEIGAMARSAAAVRVFSDDGICVSDAL
                     LMRRALEYVKAFDGVVAQHAQEPRLTEGAQMNEGCVSDRLGLPGWPAVAEEAIIARDCL
                     LAQHVGSRLHVCHVSTKGSVDIIRWAKARGCDVTAEVTPHHLLLTEELVENYDPVYKVN
                     PPLRTAEDVQALREGLADGTIDVVATDHAPHPVEAKETEWSTAAMGMVGLETALAVVQR
                     TMVDTGLLTWVDVADRMSVTPARIGRVTDHGRDLAVGEPANVVLYDPAAPYEVDGAVMT
                     TKSSNTPFRGMTLPGRVRATFLRGVPTVLEGEIK"
     gene            17881..19026
                     /gene="carA"
                     /locus_tag="PWG71_RS23085"
                     /old_locus_tag="PWG71_23085"
     CDS             17881..19026
                     /EC_number="6.3.5.5"
                     /GO_component="GO:0005951 - carbamoyl-phosphate synthase
                     complex [Evidence IEA]"
                     /GO_function="GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="carA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1249: carbamoyl phosphate synthase small subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017590402.1"
                     /locus_tag="PWG71_RS23085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_23085"
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="WP_274812037.1"
                     /transl_table=11
                     /translation="MSEETGGPAVLVLEDGRVFHGRSFGAIGETFGEIVFNTGMTGYQE
                     TLTDPSYHRQIVAMTAPHIGNTGVNDDDPESGRIWVAGYVVREPARITSNWRAKRTLDE
                     ELRRQNVVGIALTGTRALTRHLRDKGAMRAAISTVETDPKALLARVLEQPRMAGADLAG
                     EVSTDTAYEILPPEGVEARFHVAAVDLGIKAMTPQRLAERGCKVTVLPSSATVEDILAL
                     DPDGVFFSNGPGDPATADGPVSAMRGVLDAGKPLFGICFGNQILGRALGLGTYKLPFGH
                     RGVNQPVIDTATGKVAITSQNHGFAVDAPLEGTFETPYGRARVSHIGLNDRVVEGLRLL
                     DRPVFSVQFHPEAAAGPHDAAGLFDEFVDLMSAAQPTAAAE"
     misc_feature    20292..20306
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.53"
                     /tool="antismash"
ORIGIN
        1 ggtcgcgcgc cacggcgtcg cgccacatgg ggtggtcgtc cacgaccagc acccggatct
       61 cctcgctgct ctccatcaca tcctcctggg ggcccctgct ccggccggtg gggatcggtc
      121 acctcggtac cggggcccgg ccccggcacc ggagcggcga cgggaggccc gccgccgcgg
      181 cgacgagagg ggacacgcgg gtgaccttat cccgaacggg gccgcggcgc gcccgtcctg
      241 tccgctcccg gccggggaac cgaacgcggg aggggcgggg ccgcccggcc ccgcccctcc
      301 cgcgttcacc ggggccgccc cccggccgtg ctctcctgcc cggggccgcc ccccgcgtcc
      361 acgcggagat cagtcgtcat cgtcgtcgtc ctcgtcgagt tcgagctccc cgagggggag
      421 acccaccggc gtggcgatga tcgtgatctc ggtgccctcc ggtgccttgc ccgtgtggga
      481 ctgctccgcc acggtccggc cgcccaggaa gcgctccacc ttgacctcga agccggcgtc
      541 ctccagcatc tcgcgagcct ccttgacgtt cctgccgacg acgtcgggga tctccacgcc
      601 cggcgggccg gtggagacgg tcaactcgac ctcgccgccc gcgctcaacg tggtaccggt
      661 gtcgggtttc tggctgatga ccagaccatc gtcgacgctc tcgctctcgg cctcgacgat
      721 cttcaccgtc aaccccagct cctccagggc gttgcgggcg tcgtccacgc cctggcccgt
      781 gagggccggc acgtcgatgc cgcggctcac ggtgaaggtc accgtcgact cgcggtcggc
      841 ctcctcaccg ggggccgggt cggtggagat gacctccccc ggctgcacgt tctcggcgtc
      901 gacgacctct tggagcaggc tctccgggtc gaatcccagg gtctccatct ccttgatcgc
      961 gttggagacg tcctggccct tgaaatcggg catctcgacc tcgcgcggcc ccttggacag
     1021 ctggatcgtg accgtgtcac cgggggacag gcgctccccg acgttcggtt cgaccttgcc
     1081 gaccgtgccc gccgcctcgg agctgtagac gccctcctcg gccacttcgc acttcagacc
     1141 ggtgtcgcgc agggccgcgc aggccgcctc ctgttcggcg ccgatgatct cgggcaccga
     1201 ctcgaaccgg ccgacgagga accaccaacc ggcgacgaac accaccagtg ccagaacggt
     1261 cgcgcccacg gccatcagcg tcgcgcgacg acgccgatcc gggccctcgt cgaagtggtc
     1321 atcgtcgtaa tcgtcatagc cgtcgtccgc ggggccgccc atctccacga tcatggtggc
     1381 gttctcggtg cccggcccgg cgccgcccgc gatgagctgc ggcgcggtga cggccgccgt
     1441 cgtcgcggcg accggggcga ccggaggcag cggggcgccc ttcacctgcg gcgtctccgg
     1501 caggtggcgc agtacctcca gcaccttgga caggtactgt ccggcgttgc ccggccgata
     1561 ccggggatcg cgttcggtgg ccttggtgac cagggcgtcc acctcggcgg gcagcccggg
     1621 caggaagtgg gagggacgcg gaacgtcctc gttgacgtgc tggtaggcga tcgcgatggg
     1681 cgtctcgccg gtgtgcggct gactcccggt gagcaactcg tagaacatga tccccgccgc
     1741 gtacacgtcg gtgcgcgcgt cggcggtgcc ccgctcgatc tgctcgggcg ccaggtaggc
     1801 cgcggtgccc atgagggtcc cggtacgggt cagaccctgg gtggactgct ccacggcgcg
     1861 ggccagaccg aagtcggcga ccttgatccg gccgtcctcg gtgatgagga cgttctcggg
     1921 cttgatgtcg cggtgcacca tgcccgcccg gtgggcggcg cccagggccg ccagcaccgg
     1981 ggccatcacc tggagggcgt cgcgcgccga caaccggccg cgctccttga gaagggcgcg
     2041 cagggtgcga cccggcacgt actccatcgc caggaacacg tgcccccggt cctcgccctg
     2101 gtcgaagacc tggacgacgt tggggtggga gagcttggcg acggagtgcg cctcgttgat
     2161 gaagcgctgg acgaaggtgg ggtcctgggc cagcgaaggg tgcatcacct tcaacgccag
     2221 ccgacggtcc agcctcaggt cgtgggcgac gtagacggtc gccatcccgc ctccggcgat
     2281 cctggactcc acgaagtagc gttggtccag agtggcgccc acgagcgggt cggaagtcgt
     2341 catgtccacg gcggagtagt gtccttgctg cggggagcgc gggcttcgcg gtcggtggcg
     2401 cgtacccgac accgggtgtc gaaccgacac gatagcggaa gcccgacccg ggtctgcccc
     2461 gcggttcgcg gccgcgccgc ccctggtcca cggggggtgg gggcgtgcgg tcctgggtcg
     2521 tcctcgggcg cgcgacaccc cgattcgggg gacgcgcgac tctttcacgg taggcgatgg
     2581 gggcaacgcc gtggcgccgc cgcaccggtg tccttggtaa cgcccccggc cgcccgctct
     2641 gacctgcgcg aacgccggga tcatggaagt cggccccgct gggccggtcc gccggtacgg
     2701 gagggggtcc tccccgtggc ctcgggcgca cgatgagcgc ccgctgttcc gcctccccca
     2761 catgatgacg gaggggacgc ggcccccacg tgttcgaggt ctcgttcccg gcccggcgga
     2821 ccgctccgcg tcagtcgacg gcgggagagg aggcccgtgc gtgccggcgc accgggatgc
     2881 ggccggcccg tcgcgcggcg cggccggcgc gcacggcgtc gcgcatcgcc ccggccatga
     2941 gcaccgggtc ctcggcccgc gtgaccgcgc tggccagcag caccgcgtcg cagcccagct
     3001 ccatcgccag ggccgcgtcg ctggcggtgc cgataccggc gtcgacgatc accgggaccc
     3061 cggcctgttc gacgatcagc tccaggttgt gcgggttgcg gatgcccaga cccgaaccga
     3121 tcggggcggc caggggcatc accgcgacgc acccgatctg ctccagacgg cgggccagca
     3181 ccgggtcgtc gttggtgtag ggcagtaccg cgaacccctc gtccaccaac cgctcggccg
     3241 cctccaacaa ctccaccggg tcgggcagca gcgtgtgctc gtccgccacg acctccaact
     3301 tcacccagcc ggtgcccagc gcctccctgc ccagacgggc ggtgcgcacc gcgtcggtcg
     3361 cggtgaagca cccggcggtg ttgggcagcg ggcggatccc gttgcgttcc agcacctccc
     3421 acaccgagcc gcgggcgccc ggggcgaccc tgcgcatggc cacggtggtc agctcggtgc
     3481 cggaggcgat cagcgcctcc tccagcacct ccagggaggg cgcacctccg gtcccggtga
     3541 tgagccggga accgaaggag accccggaga tgaccagggg gtcgtcggtg tgcgcgttca
     3601 tggtcagccc ccctgtaccg cggtgaggac gtcgacgcgg tcgcccgcgc ccaagggcgt
     3661 gccggcccag gcggcgcggc gcaccacctc gtcgttgacg gcgacggcga tgccgccggg
     3721 gatcgcgccg ccgtcggcgg cggtcagttc gcgcacgatc tcctcgaccg tgacggtgcc
     3781 ggcggcctcg cggagggcgc cgttgacgat cagctccact gctctcactt ccaggtcgtg
     3841 gtctcgccgc ccgtgacgcg gtcggcggtg aaccggcgcg cgtacccggg cagggtcccg
     3901 gtggtcaggg cgtgggccat gacctcgccg gtgaccggtg tcagcagcac cccgtgccgg
     3961 aagtgcccac cggccaggtg caggccgggc acccgggtgg gtcccagcag cggttcgttg
     4021 tcgggggacc cggggcgcaa ccccacgcag gtctcggtga tctccagttc ggtcaccccg
     4081 gggacgagtt cacgggcgtc ccggagcacc tgccacagac cgcccaccgt gggcgcggtg
     4141 tcgtacccca gctcctcctg ggtggcgccg atgacgatct cgccgtcggc gcgcggcacc
     4201 aggtagaccg ggaagccccg gaccaggccg cgcacggtcc gctccaccaa cgggggctcc
     4261 ccggcgggca cccgggcgcg caggagctgc cccttgacgg ggcgcagcgg cggcaccacg
     4321 ggttcgggga gttcgatccg gtcgctccag cagccggcgg cgaggaccac ctgatcggcg
     4381 ggcagcgtcc ggccctcggc cggcgtcacg cccaaccggg cgccccccgg gccggggcgt
     4441 tccacggcga tcgcacggga gcggatctcg gtgaccccgg cacggtcgcc ggccacggcc
     4501 agggcccgca gcagcaggcg tgggtccacc gagtggtcct cgggggcgag cacgccgccg
     4561 cgtaccgagg gggccagcat cggctccagt cggcggcact cacggccggt gagtcgttcc
     4621 gtggtcaccc ccaggcgttt ttgcaggtcg tggaggcgat ccaggacggc caggtcgtcg
     4681 cggtcgaagg cgaccagcag agtgccggtg gcgtggtggc ccgtggggac gccgctcgcc
     4741 tcctccagtt cggcgacgaa ggcggggtac agggcggccg accggatgcc gaaccccatg
     4801 aggtgttcct caccgaacac ggcctcggtg gccggggtga gcatgcccgc cgcgacggtg
     4861 gaggcggctc gggcgccggc cgggtcggtg accgggtcgg gttcgatcag ggtgacccgg
     4921 agcccggcct gggccgcccg ccaggcggtg acccgaccga ccagaccgcc gccgacgacg
     4981 atcacaccgt gtcggtcctc cgaaggttca gaggtgggat gaatcgtgtc ggggtgcggt
     5041 gggttcgagg taggcacggt gctgctctcc actcccttcg ccggcatgac ccggatcagg
     5101 ttcgtgcggt cggaggcggt cagcctccct ctcagccggg tccacccggc tcccgcggga
     5161 cgttctacgg ttcgccccca tactacggtc ccgcccggag ggcgcccgaa accgagggcg
     5221 gcgacgtccg ggcggcgcgc gaacgtgtcc cgggcacgcg cggatatggc agattggtgg
     5281 ggtgacttca agcgattcca acctcgacac gctggtcggc acctggctga ccctcaggga
     5341 gacggcctcg ccgctggggg tgagcccgaa ccacgtcaag acgctcatcc gggagaaccg
     5401 cctcatgggc gtggtccggg gcgggcagct ctcggtcccc gccgccttca tcgacggcgg
     5461 cgacatcgtc aagggactgc ccggcaccct cgtcctgctc ggcgacgcgg gctactccac
     5521 cgaggaggcc ctgcgctggc tcttcacccc ggacgacacg ctgcccggca ccccgatcca
     5581 ggcgatgcgc gagaaccggg gcaccgaggt gcgccgacgc gcccagagtc tggccttctg
     5641 accgaccccc gtggcgggcg cgccgtgtcg cccgccccct tggggtagcc gggtccaagg
     5701 cctaggctgg tgaccgtgag gaccagccac ggaaccagcc tgcgcaagcg cctggacgca
     5761 tcccttctgt acctgtgcac cgacgcccgt cgcgaacgcg gtgatctcgc cgagttcgcc
     5821 gaggccgccc tgtccggggg agtggacatc gtccagctcc gggacaaggg cctggaggcg
     5881 cgcgaggaga tcgccgccct ggaggtgctg cgggaggcgt gcgaacgcca cggcgccctg
     5941 ctcgcggtca acgaccgcgc cgacatcgcc cgcgccgttc gcgccgacgt gctccacctg
     6001 ggccggcgcg atcttccggt gcccatggcc cgcgacatca tcggcgcgga cccgttgatc
     6061 gggcgctcca acaacgacat cgacgccgcc cgggcctccg cggaggaacc gggcagcgac
     6121 tacttctgcg tcggcccggt atgggagacg cccaccaagc cgggccgtcc ggccgccgga
     6181 acggaactgg tggagcgcgc ggccgcgctg aacagcgacc ggccgtggtt cgcgatcggc
     6241 ggtatcgacc tcgacaccgt ggaccgggtc ctggatgccg gggcccgccg cgtggtcgtg
     6301 gtgcgcgcca tcaccgaggc cgaggacccg cgggcggcgg ccgccgccct gcgcgcccgc
     6361 gtcatcgacc gtcagggctg agaaccgcgt cggccccggt acacgacccg gggccggcgt
     6421 cgttccgtcc ggtgcgggcc ggggccggac ctcggagacc gaacgcgtgg cctcctccgc
     6481 ccggaccacc ccggtcaggg gatcagcagt accttgccga gcacccggcg ctcctccatg
     6541 gcccggtgcg cctccgccgc gtcctccaac ggcagggtca gcccgatgtg gggggtcagc
     6601 ctcccggacc ggaccagctc cagagcctct cccagggcgc gcgtcctggc ctcggcctcg
     6661 tccttgatgt cgaacaggcc gaagacctcg acctcgtgct ccagggcccg ggcgggctcg
     6721 atctcggcga accggccgcc ggccgatccg tacccgacga accggccgcc ccgggccacc
     6781 gtcgtgaagg cctcctcgcc cagggacgcc ccggccccgt ccagggcggt gtccaccccg
     6841 ataccgccgg tgagctccag gacccggtcc gtccaccccg gcagggagta gtccacgacc
     6901 tcgtgcgcgc cgagcttttc ggccagggcg agcttgtccc cgcccctcgc ggcggcgatg
     6961 acccgcgctc cggcgttccg ggccagctgg accgacaggc tgccggcgcc gccggtggcc
     7021 gcggccacca gcacggtctg ccccggtcga taatcggcgg tccgggccag ggcgagcgcg
     7081 gtggggccgt cgtgcagcag ggccagggcg tggtgcgggt ccaccccctc gggcacccgg
     7141 atcagatccg actccgggac caccgcccgc tcggcgtagc cgccgaccgg tagggcgctc
     7201 ccgtcggcgg tcctctcccc ggtgtcggtg accacccggg tcccgaccca ggaggggtcc
     7261 acgccctcgc cgacccggga caccgttccg accacaccgg tcccggggac gtaggggggc
     7321 gtcacgggga agaagtcgcg tccccacccg gaccggacca gcacctccag gtacatcacg
     7381 ttggccgcgt ccaccgtcac ctcgaccgag ccgggcccca cctcggggtc gggcacctcc
     7441 cgggccgtca gaacctcggg accgccgaac ccgtcgactc gtaccgcgcg catgtggatc
     7501 ctccatcgat ggtcgtccgc cgcgaactcc gcgacatcga ccactctggt acctcaacta
     7561 atattgaggt caatacccgg gtgaaagaag tgttccggcg cggcaccgga acacccgtca
     7621 gacggacacg tgcgacagcg cgctcggatg acggcgcagg aagccctcga tcgaacgggc
     7681 ggggtgaccg gtcaccttct gtaccgtggc cgccacctcg tccagctccc cggcggcgat
     7741 cgcctcgtac gaggagaccc atccctcgat ctcccactcg ggcgcccccg tggccttgcg
     7801 ggacaacagg gcctcctccc gggtctcggg cacgtacctg atggtccggc ccgtcaacgc
     7861 gctcaaccgt tcgacggtcg cccccaggga gagcgcctcc gggccggtca cgtcgtaggt
     7921 cgcgttctcc gccgccgcgg ccagggccgg atcggtcagc accgccgcca ccacgtccgc
     7981 gatgtcgtcc cgggccaccc acgccacccg gccctcaccg gcggggccgc gcaccacacc
     8041 gctctcgtcc acccagtgcg gcagcaggtc caggtacagg gagggtctca ggaacgtgta
     8101 cctcactccc gtcgtccgga tgtgggcctc ggtgaagaag tgcgtccgcg cgaaggtgaa
     8161 cgtcgacgcc ggccccgctt gcaggaagga caggtagacg attcgtgaca cccccgccgc
     8221 gaccgccgcg tcgaccgcgc tcaggtgcgt gtcgatccgg tcctccgact ccgtcgccgg
     8281 gaccaggaac agcgtgtcca ccccacggca ggcccgtgcg aagttcgcgg tgtcctcata
     8341 ggccgccatc gcggcggtgc tgcccgggtg atcgggcgcc cggttcaggt cccgcacgat
     8401 gagccgctgc gcccggccca gccgcgcgat gcgggcggcc acccgcccgc ccaccgcccc
     8461 ggtcgccccg gtcaccccta tggtgtggtt tgtcatgtga tcgtcgccca tgacacccca
     8521 tcctgaacga cgagggcgtg ccgggcactc accggcacgc ccgtttttac gcccacgggt
     8581 cagggagtgg cccgctcttg atcctccccc tcgggcggca ccgtgccgac cggcacgggt
     8641 tcccgcgtgc tgtgccggta ggcgagccgg cgcagcagca cctcggccgg cccccgcacg
     8701 cccgcccgct ccatgaggta ggcggccacg acggtgatca gccacacccc gatcgcgtac
     8761 aggaacatcg tccacgaggt caggtacgcg gccagcccca ggccccacgc ggtcaggatc
     8821 ggcgcgcaca gcaccgactg ggccaggtag gacgacaggg agcgcttgcc ggtggcggtg
     8881 atcgcggtca gtacgacgcc gggctcgcgc ccgcgtccct ggatcgcgtg cgcgatcagg
     8941 gcgatcaggg cgacgtaccc cagcccgccg aacagtcccg ccaacatgtg cggcatggcc
     9001 agcatcgagg cctgggtggg gttcggctcc cagacgccga cctgggccag cgcgttgggc
     9061 aggccgccca gccagccgat ggcgatgccg agcccggcgg tccatcgcag cagcgggagg
     9121 tgggaccccg gctcctccag cacccggcgg cgcgccgccc agaaggcgag caggatcatg
     9181 gtcggcacga ccagcgccac gaggccctgg acgacggtga tcaggggcca gacgatgacg
     9241 cgaccgagcg cggcgcccag gatcgaggtc tcggcggcgc tcgccgccat cgcgtccatc
     9301 ccggtcccgg agctcgggcc gtccggtgcc aggaccatcc ccacgacgct gaacgcggtc
     9361 agcgcggcga ggagaccgat gaacaccgag gcccacacca gcagggtggt gtccttgcgg
     9421 cgcaggaaca gccatcccag gagcaggccg gccagaccgt aggcgcccag gacgtcaccg
     9481 aaccacagca gcagggcgtg gaagaacccg aacgcgagga gccacaggtt gcgtcggcgc
     9541 aacagcgcgt tgacgtcctt gacgctcgcc ccggcggcct cctggcgcat ggccagctgc
     9601 accatgccgt agccgaacag gaacgcgaac atcggatagc tgcggccgtc caccaccatg
     9661 atggtgaaga actgggtcac ggagtcgagc gtgctctccg gggccgggtg ggcgcccagc
     9721 tcgcccatgg ggaccgtcca caggtaccag acggtgttgg ccagggcgat gaacaggagc
     9781 atgaacccgc gggccaggtc gggggcgagc gctcgttcgc ccgctccggc cggcccgcgg
     9841 gccacggcgt tccgagacat ggatggatcc ttccggtcgc gatatatctc ttatcgattc
     9901 aaccggaggg acgagtcggg cacaatgcac tttcgtaggg tgaaagaccc tgaaacattc
     9961 cttaggggaa tacccccgtg cgggtccgcg cgcgtcggat tcagtgcgtg cggcgggtgg
    10021 cgaccgccac catcgtgcgc agcggctccc gggcggcgtc gtccagctcc gggctctcca
    10081 acgccgccag cgcctcctcg gaatagcgct cgacgagctc ctcacaggcg gccagcgcgc
    10141 cggaggactc gatgagcccg cacatccact cgaccgaccc caccgacagg tcgggcgcgc
    10201 ccagcagagc ggtgaagcgc gcgccgtcgg cggcgtccga gcgcgccagg gtctcggcga
    10261 ccaccagggt ccgcttgccc tcgcgcaggt cgtcaccggc cggcttgccg gtggtggacg
    10321 ggtcgccgaa cacgcccagc acgtcgtcgc gcaactggaa ggccaccccg agcggtatgc
    10381 cgtaggcggt gtagacgccc tccagctccg gcaggcgacc cgccagcgcg gcgcccaggt
    10441 gcagcggccg ctccacggtg tacttggcgg acttgtaccg catcacccgc agcgccgcct
    10501 ccctggtgcc ggtaccgcgc acctgctcca gggtgtccag gtactgtccg gccatcacct
    10561 cggtgcgcat cgcgtcgaag ggccgccgcc cccacgcgag ggtgtcctgg gcgaacccgc
    10621 tggcctggta catctcgtcg gaccaggcca gacacaggtc gccgatgagc acggccgcgc
    10681 cccggccgaa gccctcgccg tcaccgctcc agccgcgctc ggcgtgcaac ccggcgagcc
    10741 gcttgtgggt ggcgggcagg ccgcgtcggg tgtcgctgtt gtcgatgacg tcgtcgtgga
    10801 tgagcgcgca ggcctggagg aactccaggg aggccgccgc ccgcacgatc cgctcgtcgt
    10861 ccgccgcgcc cccggcgccg cgccacccct ggtaacagaa ggcggggcgc aggcgcttgc
    10921 ccccggtgag catcgcctcc agcgcgtcca tggccggggc caactcctcc ccgacctcca
    10981 gcagggtgag ccggtggtcg gcgcagaacg cgtccagttc ccggtccacg tccgagcgga
    11041 tcgcggagac gggggagagg gaggaggatg atgagaaagc ggccataccc agcacattag
    11101 cggctcaccc cgagggcccc gcccctttcc gcgcccccgg tcccttccac atcgccacca
    11161 ggacgaacga caccgtcacg agcagggccc aggcgcccag cttggccggg tggaccagcg
    11221 cccagacctc cgcctggtgg gggtagcgcc aggcgtcgaa cagcgtcgag atgttctccg
    11281 ccacccacag gaagaacccg atgaacagga acgacaacgc caacggcagg cgcggccgct
    11341 gttcccccac ggtgaagtgc acccacgtgc cccaggtcac cgcgatcaac agcaccgcca
    11401 gcgggatccg caggtcgggc agccagtggt gggtgaggaa gttcgcgtag atcgcgatcg
    11461 ccaccgccgt gacggcccac gagcggtagt tcgtcaaccc caggtcgaac aggcgccagg
    11521 cgcgcacgat gtaggagccc accgccgcgt acatgaaccc gctgtagagc ggcacgcccc
    11581 acaccacggt ccacccgggg ccggggtagg accacgaacc catgcgcacc ttgaacagtt
    11641 cgaacgccaa ccccaccacg tggaatccgg cgatcgcggc gatctcccgg ccggtctcca
    11701 gccgcagcgc ccagaacagc gcggtcaccg ccaccgcgta gatcaacagc gcgtcatagc
    11761 gggcgatcgg cagggggacc gccatcgaca gcgcgaaccc ggcgaacatg cacgccgcga
    11821 acgcgcaggc gcgggcctgc aacaggccga agcgcgtcag ctgcgcgaag aagaaggtca
    11881 cggaggagaa ggacgcgcgg cggcggtccc cccgcgcccg ccgtggttcg cgggcgcgcc
    11941 ccgatgtgat cctcgttctc ggtctcactc agtgggatgt cccttccatc cggtcagggg
    12001 gcctcaccta cagtggtgtg catgctggct gcaccgacac gccccgtgac gccccgaacc
    12061 cccgaacccc ggccgcgaca catccgtgac ctgctccgca cgggtgagcc gatgttctcc
    12121 ttcgagttct tcccgccccg gagcccgcag gccaatgagc gactctggcg ggccatccgg
    12181 caactggagg ccctgggtcc cgccttcgtc tccgtcacct acggcgcggg cggcagcacg
    12241 cgcggtatga ccgtggagac caccgagcgg atcgcgaccg acaccacgct cctcccggtc
    12301 gcgcacatga ccctggtcga gcactccgtc gccgagctgc gtcacctcat cggccgtctg
    12361 gccgacgccg gggtgtccaa catgctcgcg gtgcgcggcg acccacccgg agacccctcc
    12421 ggcccgtggg tcagccaccc cgagggactg acctacgcag aggagctggt ccggctcatc
    12481 aaggacagcg gcgacttctg cgtgggcgtg gcggccttcc cctacaagca cccgcgctcg
    12541 gccgacgtgg agaccgacac cgacttcttc gtgcgcaagt gcgacgcggg cgcggactac
    12601 gccatcaccc agatgttctt cgaccccgag gactacctgc gccttcggga ccgggtggcg
    12661 gcccgcggct gtgacatccc gatcatcccc gaggtgttcc cggtggtgcg cacgtcgttc
    12721 atcccgcgct cggagaagct ctcgggggcg ccgttcccgg cggacctggc cgcgcggttc
    12781 gagtccttcg gcgacgacac cgaggcggtg cgcgccttcg ggatcgagca cgcccagcac
    12841 atgtgcgagc ggctcttgga ggagggtgct ccgggcatcc acttcatcac ctcgaatcag
    12901 tccaccgcca ccagggagat ctaccgggag gtgtcgggac gacggcgccc gtgagcggca
    12961 ggcgcgtcgc catgatcgag aagggccggt ccgggctgcc ggggaaggag aactcctcca
    13021 gcacctcgac gaacccgcag gagcggtaga ggtgacgcgc cgccgtgggg ccggcccggg
    13081 tggacaggat cgcggtgcgc tcgggccggt ccgagcacag ggcgtgcagg acggcccggc
    13141 cgatcccccg gttctgcgcc tcggggtgga cgtgcacctc ggcgatctcg aacgcgtcgg
    13201 tcatccagcg gcgcgccccg gcacggccgc cctcggcgcg cagacccgcg gagacggtgt
    13261 cgtgccacca ctggccgcgc gcgccgtgga aggcgtaggc gaaaccgatc ggacgctcct
    13321 ccagcacggc gacgatggac cggaacccgg gatggcggga gtgggtcttc atgacggagg
    13381 cccgtcccgg caactgctcg ggcgggggtt ccatggccgc ctcgtacacc tggaggaggg
    13441 cgggaacggc gtgcgcgaac gccggggggc ccagctcgcg cagctcgaca tcggctacca
    13501 cgacttcaca ctagcctccg aaggcgtgtg cccgacggat ttcggcgtgg ccgataccgg
    13561 ttgtccgccg gtcctcgaca cgcccgggag gggtgccgcc ggtccttgac gggtcgtcga
    13621 gggcggggtt aactgttgat cgtcgaacat gagttcgaca tcggccgtcg gggcgacccg
    13681 gcggcgacgg cgcggccggc tcggggaggg gaagccccgt gtccgaccgc gccgttccgt
    13741 cgtgcccgcg ggtgagggcc cgtatacgac gaggaccggc ccgccctcga tgggcgggcc
    13801 ggtcctgcgg cgggcgggtg cgatccgtgc ctggacgatc agaaggagtc gacggcgcga
    13861 cgggcctccg ggtcgaggac gccccagttg atgagctcct cggtcaggtc gccgggcgac
    13921 ttgtcgtaga tgaccgcgag cgaacgcagg tcctcctgac ggatggagag cacgcggccg
    13981 ttgtagtcac cgcgctggct ctggatggtg gccacgtagc gggacagcgg gccggccttc
    14041 tcctgcggga gctgctgcat gcgctccagg tcgatgacca gcttgggtgt cgggcccagg
    14101 ggcgtggggg cggcaccgcc gggcagcagc tccgacatcg gcacgccgta gaagtcggcc
    14161 agctcggcga gcttctggac ggtgacggcg cggtcgccgc gctcgtagga gcccaccacg
    14221 acggccttcc agcgtccgtg ggacttctcc tccactccgt ggagggacag gccctgctgg
    14281 gttcggatgg cacgcagtcg cgcgccgagg gacttggcgt attcggatgg catcttcttg
    14341 tcgctcccgg ccgtgacagt ggctggcgtg atgggggaga gacccgttcc aacgagggcc
    14401 gtcggacggt ccctcggagg tcacggggtg caaccccacc cggcaatggt tacagacagt
    14461 gacggtaggg gggtccgtcc cccaggtcaa gccgttggtg tgaaacgcga ctaatcagtg
    14521 gccaaaccgt gcgtaagtga gactcctctc atgtccacgc ggaccgtgac gagaggtgca
    14581 tcacgcccat gcgaaaagcc cgttctttca gggggtttcg catttgtcgg ccatgtgagg
    14641 tgtgtgcaga tcgtagccgt cgcgttgctc tgaggatcct ctgcgccctt tgtgtatgtg
    14701 atgagagtca cactactcga tatccacctt gagcccgccc tcggtgacct cgaacgccgc
    14761 tggtagcgtg ggcccgatcg acatccttta acgacctgtc ccgtgaggca gggaaggggt
    14821 cactgctttg tgtgcgcgaa aaaccacgac gagtgacacg aacggtggcg tggcgccacc
    14881 ggagatgccc gaaggcaccc gggccgtcct cgacggcaac gagatcaacc gggcgttgac
    14941 ccgtatcgcc cacgaggtgc tcgaacggac caagggcgga cacggggtca ccctcctcgg
    15001 catcccctcg cggggagtcc ccctcgcggc ccgcctggcc gagcgcatcg aacacgtcga
    15061 gaaactggcc gtcccccacg gctccctcga catcaccatg taccgcgacg acctgcgcac
    15121 cgccccgccg cgggccttgg gccggaccga gatccccgac ggcggactcg acgaccgcgt
    15181 cgtcgtcctc gtcgacgacg tcctcttctc cggccgcacc gtccgcgccg ccctggacgc
    15241 gctcaacgac ctgggccgtc cccgcgccgt ccagctcgcc gtcctggtcg accgcggcca
    15301 ccgccaactg cccatccgcg ccgactacgt gggcaagaac ctgcccacct cgctgcgcga
    15361 gagcgtcacc gtccggctca ccgagaccga cggccacgac gcggtgctgc tcggcccgtc
    15421 ccgcccgtcg tcctccgcca ccctcacggg cggcccgctg cccggtgccc tcggccgacg
    15481 ccccgacacc gacggcaccg aggggaagga ctcctgatgc gccacctgct ctccaccggg
    15541 gacctcaccc gcgacgaggc cgtcctcatc ctggacaccg ccgccgaact cgcccgggtc
    15601 ggcgaccgct ccgtcaagaa actccccacc ctgcgcggcc gcaccgtggt caacctcttc
    15661 tacgaggact ccacccgcac ccgcacctcc ttcgaactcg ccgccaagcg cctgtccgcg
    15721 gacgtcgtca acttctccgc caagggctcc agcgtctcca agggagagag cctcaaggac
    15781 accgccctca ccctccaggc catgggcgcc gacggcgtcg tcatccggca cagcgcctcc
    15841 ggcgcggccc accgcctggc gaactgggtg gacggatcgg tcctcaacgc cggcgacggc
    15901 acccacgagc accccaccca ggccctgctc gacgcctaca ccatgcgcgc ccgcctgggc
    15961 cgcctggagg gcctgcgcgt ggccatcgtc ggcgacatcc tgcacagccg ggtggcccgc
    16021 tccaacgtgt tgctgctcac caccctgggc gcccacgtca cgctcgtcgc gccgcccacc
    16081 ctgctgcccg tctcggtgcg cacctggccc tgcgaggtct cctacgacct cgacgaggtc
    16141 ctgcccaagg ccgacgtcgt catgatgctg cgcgtccagg ccgagcgcat gcacgcctcc
    16201 ttcttcccct ccgtgcgcga gtacagccgc ggttacggga tcgacggcgc gcgcctgtcc
    16261 cgcatgcccg aggacgccat cgtcatgcac cccggcccga tggtccgcgg catggagatc
    16321 tccgccgagg tcgccgactc cccgcgctgc accgtcgtcg agcaggtcgc caacggtgtc
    16381 agcctgcgca tggccgtgct ctacctgctg ctcggcggct cctgacacca caccggcgcg
    16441 ccgaggcgcg cccgcgcggt gtgaggacga ccgccgcccg cgcgcacgag atcttctttc
    16501 acgaacgacc acgaggaacg aaaccgcgat gcccgacaac cacggaccgc acctgatccg
    16561 cggcgcccga ccactcggcg ccgaccccgc cgacatcctg atcgtcgacg gccgcatcgc
    16621 cgagatcggt accgacctcc gggcccccga gggcaccgag gtcgtggacg ggaccgggct
    16681 gatcgccctg cccggactgg tggacctgca cacccacctg cgcgaacccg gacgcgagga
    16741 cgccgagacc gtcgagaccg gctcccactc cgccgccatg ggcggctaca ccgccgtcca
    16801 cgccatggcc aacaccgacc ccgtcgccga caccgccggt gtcgtcgaac aggtctggcg
    16861 tctgggccgc gaggccgggt actgcgacgt gcgccccgtc ggcgccgtca ccgtcggcct
    16921 ggccggcgag cgcctctccg agatcggcgc catggccagg tccgccgccg ccgtccgcgt
    16981 cttctccgac gacggcatct gcgtctccga cgccctgctc atgcgccggg ccctggagta
    17041 cgtcaaggcc ttcgacggcg tcgtcgccca gcacgcccag gaaccgcgcc tcaccgaggg
    17101 cgcccagatg aacgagggct gcgtctccga ccgcctcggc ctgcccggct ggcccgccgt
    17161 cgccgaagag gcgatcatcg cccgggactg cctgctcgcc cagcacgtcg gctcgcgcct
    17221 gcacgtgtgc cacgtctcga ccaagggctc ggtcgacatc atccgctggg ccaaggcccg
    17281 cggctgcgac gtcaccgcgg aggtcacccc ccaccacctg ctgctcaccg aggagctcgt
    17341 ggagaactac gaccccgtct acaaggtcaa cccgcccctg cgcaccgccg aggacgtcca
    17401 ggcgctgcgc gagggtctgg ccgacggcac catcgacgtc gtcgccaccg accacgcgcc
    17461 ccaccccgtg gaggccaagg agaccgaatg gtccacggcc gccatgggaa tggtcggcct
    17521 ggagacggcg ttggcggtcg tgcagcgcac aatggtcgac accggcctgc tgacctgggt
    17581 cgacgtcgcg gaccgcatgt ccgtcacgcc ggcccgcatc ggccgggtga ccgaccacgg
    17641 cagggacctg gcggtcggcg agcccgccaa cgtcgtcctg tacgaccccg ccgcgcccta
    17701 cgaggtcgac ggcgcggtca tgaccaccaa gagcagcaac acgcccttcc ggggcatgac
    17761 cctgcccggt cgggtgcgcg ccacgttcct gcgcggcgtc cccaccgtcc tggagggtga
    17821 gatcaagtga acaacgcagt gggcgtccag gccgtgcctg gcgtcgtaga gggggagaac
    17881 gtgtcagagg aaaccggcgg accggccgtc ctggtcctgg aggacggtcg ggtcttccac
    17941 ggccgctcct tcggcgccat cggcgagacc ttcggcgaga tcgtcttcaa caccgggatg
    18001 accggttacc aggagaccct caccgatccc tcgtaccacc gccagatcgt ggcgatgacc
    18061 gcaccccaca tcggcaacac cggggtcaac gacgacgacc ccgagtccgg ccgcatctgg
    18121 gtcgccgggt acgtcgtgcg cgaacccgcc cgcatcacct ccaactggcg ggcgaagcgc
    18181 accctcgacg aggagctgcg ccgccagaac gtcgtcggca tcgccctgac cgggacccgc
    18241 gccctcaccc gccacctgcg cgacaagggc gccatgcggg ccgcgatcag caccgtcgag
    18301 accgacccga aggccctcct ggcccgcgtc ctggagcagc cccgcatggc cggcgccgac
    18361 ctggccggcg aggtcagcac cgacaccgcc tacgagatcc tgccgcccga gggcgtcgag
    18421 gcgcgcttcc acgtcgccgc cgtcgacctc ggcatcaagg ccatgacgcc ccagcgcctg
    18481 gccgaacgcg gctgcaaggt caccgtcctg ccctcctccg ccaccgtcga ggacatcctc
    18541 gccctggacc cggacggcgt gttcttcagc aacggccccg gcgaccccgc caccgccgac
    18601 ggacccgtct ccgcgatgcg cggggtcctc gacgccggca agcccctgtt cggcatctgc
    18661 ttcggcaacc agatcctcgg ccgcgccctg ggcctgggca cctacaagct gcccttcggc
    18721 caccgcggtg tgaaccagcc ggtcatcgac accgccaccg gcaaggtcgc catcaccagc
    18781 cagaaccacg ggttcgccgt ggacgcgccg ctcgaaggga ccttcgagac cccctacggc
    18841 cgcgcacggg tcagccacat cggcctcaac gaccgggtcg tcgagggcct gcggctgctg
    18901 gaccgtcccg tgttcagcgt ccagttccac cccgaggccg cggccggtcc ccacgacgcc
    18961 gccggactct tcgacgagtt cgtcgacctg atgtccgccg cccagcccac cgcggctgcc
    19021 gagtagttag gaaccaagag catgccgcgc cgtagtgacc tctcctccgt cctcgtaatc
    19081 ggatccggcc ccatcgtcat cgggcaggcg gccgagttcg actactcggg cacccaggcc
    19141 tgccgcgtcc tgcgggccga gggcctgcgg gtcatcctgg tcaactccaa cccggccacg
    19201 atcatgaccg acccggagat cgccgacgcc acctacgtcg agccgatcac caccgagatg
    19261 atcgagaaga tcatcgccaa ggagcgcccc gacgcactcc tgcccaccct gggcggccag
    19321 accgctctca acgccgccgt cgccctggac gagagcggca tcctcgacaa gtacggtgtc
    19381 gaactcatcg gcgccaacat cgaggccatc cagtccggtg aggaccgcga gaccttcaag
    19441 cggatcgtcg agcgcatcgg cggcgagtcc gcccgctcca gcatctgcca caccctcgcc
    19501 gagtgcctcg acgccgccga cgagctcggc tacccggtcg tcgtgcgccc gtccttcacc
    19561 atgggcggcg ccggctccgg cttcgcccac gacgcggacg agctgcgccg catcgccggc
    19621 cagggcctcg cgctctcccc gaccaccgag gtcctcctgg aggagtccat cctcggctgg
    19681 aaggagtacg agctggagct gatgcgcgac accaacgaca acgtcgtggt cgtctgctcc
    19741 atcgagaacc tcgaccccat gggcgtgcac accggcgact ccatcaccgt cgcccccgcc
    19801 atgaccctca ccgaccgcga gtaccagaag ctccgcgaca tcggcatcgc ggtcatccgc
    19861 gaggtcggcg tggacaccgg cggctgcaac atccagttcg ccgtggagcc cgccaccggc
    19921 cgggtcatcg tcatcgagat gaacccccgg gtctcgcgct cctcggcgct ggcctccaag
    19981 gccaccggtt tcccgatcgc caagatcgcc gccaagctcg ccatcggcta caccctcgac
    20041 gagatcccca acgacatcac caaggagacc ccggccagct tcgagcccac gctcgactac
    20101 gtggtcgtca aggccccccg gttcgcgttc gagaagttcc ccggcgccga ccccacgctc
    20161 accaccacca tgaagtcggt gggcgaggcc atggccatcg gccgctcctt ccccgaggca
    20221 ctccagaagg ccatgcgctc cctggagaag cccggtgtcg ggttcacctg ggccggcccg
    20281 gtcggcgaca aggacgagct ggtccgcgcc gccgcccagc ccaccgagca ccggctgcgc
    20341 caggtccagc aggccttccg cgccggcgcc accgtcgagg agctgtacga gtccacgcgc
    20401 atcgacccct ggttcctgga ccagatgctg cgcctggagg agaccgcccg cgccctggcc
    20461 gccgcgccca agctcgacgc cgacgcgctg cgcgccgcca aggggatcgg cttctccgac
    20521 gtccagatcg gggagatcac cggcaagagc gaggacgtcg tccgcgagct gcgccacgcc
    20581 ctgggcatcc accccgtcta cctgaccgtg gacacctgcg ccgccgagtt cgaggccacc
    20641 acgccctacc tgtactccag ctacgacgag gagaccgagg tccccgtcgg cgacaagccc
    20701 aagatcatca tcctgggctc gggccccaac cgcatcggcc agggcgtgga gttcgactac
    20761 tcctgcgtcc acgcctcctt cgcgctgtcc gccgccgggt acgagaccgt gatggtcaac
    20821 tgcaacccgg agacggtctc caccgactac gacaccagcg accggctcta cttcgagccg
    20881 ctcaccctgg aggacgtcct ggaggtcgtc cgggccgagc agctcaccgg caccgtcgtc
    20941 ggggtcatcg tccagttggg cggccagacc cccctgggcc tggcccgccg actcaaggac
    21001 gccggggtgc ccatcatcgg caccagcccc gaggccatcg acctggccga ggaccgcggc
    21061 gcgttcggca aggtcctggc cgacgc
//
