LOCUS       NZ_JARBUT010000004     21053 bp    DNA     linear   CON 29-APR-2024
DEFINITION  Nocardiopsis sp. N85 Scaffold4, whole genome shotgun sequence.
ACCESSION   NZ_JARBUT010000004
VERSION     NZ_JARBUT010000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardiopsis sp. N85
  ORGANISM  Nocardiopsis sp. N85
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Nocardiopsaceae; Nocardiopsis.
REFERENCE   1  (bases 1 to 353137)
  AUTHORS   Liu,S.
  TITLE     Nocardiopsis sp. N85
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 353137)
  AUTHORS   Liu,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-2023) Microbial Chemistry, Institute of Medicinal
            Biotechnology, Chinese Academy of Medical Sciences, Tiantanxili No.
            1, Beijing 100050, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 1.05
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 182.0x
            Sequencing Technology :: combinatorial probe-anchor synthesis
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028882275.1-RS_2024_04_29
            Annotation Date                   :: 04/29/2024 06:01:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,729
            CDSs (total)                      :: 5,663
            Genes (coding)                    :: 5,611
            CDSs (with protein)               :: 5,611
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 9 of 53
            Pseudo Genes (incomplete)         :: 46 of 53
            Pseudo Genes (internal stop)      :: 0 of 53
            Pseudo Genes (multiple problems)  :: 3 of 53
            CRISPR Arrays                     :: 13
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:47:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 159548
            Orig. end                         :: 180601
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JARBUT010000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21053
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21053
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21053
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11053](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11053)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    1155..1169
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    complement(1393..1406)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.93"
                     /tool="antismash"
     misc_feature    complement(1396..1409)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.77"
                     /tool="antismash"
     misc_feature    complement(1397..1412)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.24"
                     /tool="antismash"
     misc_feature    1400..1415
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.81"
                     /tool="antismash"
     misc_feature    complement(1400..1418)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.5"
                     /tool="antismash"
     misc_feature    complement(1402..1415)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.41"
                     /tool="antismash"
     misc_feature    1402..1416
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: strong, score: 25.36"
                     /tool="antismash"
     misc_feature    1403..1416
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.05"
                     /tool="antismash"
     misc_feature    complement(1403..1418)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.58"
                     /tool="antismash"
     misc_feature    complement(1404..1415)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.23"
                     /tool="antismash"
     gene            1528..2325
                     /locus_tag="PWG71_RS08130"
                     /old_locus_tag="PWG71_08125"
     CDS             1528..2325
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017536489.1"
                     /locus_tag="PWG71_RS08130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_08125"
                     /product="methyltransferase"
                     /protein_id="WP_342455948.1"
                     /transl_table=11
                     /translation="MHSPSSPANRTGTPVRPGAATGWELHGLLPQTLSAEEIRAINDPG
                     RAIHEHRAYTWNGWDFDLPPGVFHPGETSRLVHTRLLDGTLPVAGLRYAAMGAGLGVEA
                     VVAGVRGASVVYALDVHPESVRTTTRHYERIVGADGPPLVPLVTDVWEGFPGGEQVDVV
                     TFNPPAIELPLSDDPEIVRNLCLGRDIATRFFDQLVARDLLAAGGVVYLILSNTAPLRD
                     IVALGLRAGFDAEVVHVEDWPGDDVQTYLFALRRPGGRPGGED"
     gene            2331..3374
                     /locus_tag="PWG71_RS08135"
                     /old_locus_tag="PWG71_08130"
     CDS             2331..3374
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017598479.1"
                     /locus_tag="PWG71_RS08135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_08130"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_274808941.1"
                     /sec_met_domain="PALP (E-value: 4.4e-32, bitscore: 105.8,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHEHYADAIADPDCIRLAPDLVCLRFEVMKVRSALGAVRHLLDTG
                     AVRPGDTLVDSSSGIYALALALACHRYGMRCHIVGSSTVDETLRVQLEVLGATLEQMPP
                     SDDLMLDQNRRVERVGRLLLENPGFHWMRQYHDAIHYVGYREVAEQLDREVPTGPLTIV
                     SGVGTGSSTGALGCYLRAAGRDVELVGIQPFGSVTFNAEHTADPDMIIAGIGSSIEFRN
                     VRHELYDRIHWVSFEYARAGAVALLRDSGVFAGLSAGAAYLAAGWEGGRTAGRTVVFLA
                     PDTGHRYVRAAFAAHAHVPGIADLSPHEVADSDGIALPWSVADRTALSASWRDAVPVAV
                     RAPSGSP"
     gene            complement(3510..4244)
                     /locus_tag="PWG71_RS08140"
                     /old_locus_tag="PWG71_08135"
     CDS             complement(3510..4244)
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017584816.1"
                     /locus_tag="PWG71_RS08140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_08135"
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="WP_274808942.1"
                     /sec_met_domain="Abi (E-value: 6.9e-18, bitscore: 59.2,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTDHPARPQNHDAVGDASPVRPGWTEIVVGLLALSITVVALVLL
                     GPAGPLDPDPVTFGLITAAWSGIAGLVGFAAAWAVRVRSLGAFGVRRTTWRWMLIGAGW
                     GVVALVVKGAVILAITALTGFDDDPQGMYYDAAGGGGLALVLTILFLAVLTPIGEEFLF
                     RGVVTNALLRYGPVVGVLGGSAIFAVFHGVNIILPAAFVVGVIAAEVMRRSGSVWPAVA
                     VHSVNNLALPLLVLFTGFTGPA"
     gene            complement(4324..4962)
                     /locus_tag="PWG71_RS08145"
                     /old_locus_tag="PWG71_08140"
     CDS             complement(4324..4962)
                     /GO_function="GO:0070273 - phosphatidylinositol-4-phosphate
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017584817.1"
                     /locus_tag="PWG71_RS08145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_08140"
                     /product="GPP34 family phosphoprotein"
                     /protein_id="WP_274808943.1"
                     /transl_table=11
                     /translation="MDMTLPQRLYLLTYDIDGNRFDPVSTPYRGHLLRAAALTELIIGG
                     LLRDNGGRAERTGRTPDDPFLADVLSGLSPNEPGHWINAVPDREWKAETTVREQLVANG
                     SITVVRGRVLGMFPSRKVTLDHPERVRLLRERTRDAVLAGREAASVPIEDAALAAIAVE
                     GDVWTVFTPAERQRHRAEVKALRERFEAEVPGMLNAILTAVVNRRAGTS"
     gene            complement(5098..5814)
                     /locus_tag="PWG71_RS08150"
                     /old_locus_tag="PWG71_08145"
     CDS             complement(5098..5814)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017566557.1"
                     /locus_tag="PWG71_RS08150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_08145"
                     /product="ABC transporter permease"
                     /protein_id="WP_274808945.1"
                     /transl_table=11
                     /translation="MLAIAHGELIQIFRNRLVLVTMLVMPAAASAFYIYLHDRIPGLAL
                     GTVAAVLMFLVVVMGLYTTAVTTLASRRQNLFLKRLRSTAVDDARILTGLLLPVTAITV
                     VQVAVVLTVLSIVAEPPADLLLLVAATLATVVMMLGLALATAGVTNSPEHAQVTTLPVL
                     LGVLVVSGWVGFTGTEELTLLKRLLPGGAAAELVVDAWDGGVPVADSLFLLAPTLAWVV
                     VAVGLAARIFRWEPRR"
     gene            complement(5873..6757)
                     /locus_tag="PWG71_RS08155"
                     /old_locus_tag="PWG71_08150"
     CDS             complement(5873..6757)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019610904.1"
                     /locus_tag="PWG71_RS08155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_08150"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_274809099.1"
                     /transl_table=11
                     /translation="MSSTPVIDVERLNVRYGDFHAVKDLSFQVRRGELYALLGTNGAGK
                     TSTLETVEGHRPATSGTVRVFGRDPRDRGSVRPRTGIMLQESGFSPDLTVRESIRLIGG
                     LTRRTDRVERLLGVVGLEHKADTRVSRLSGGEKRRLDFATAVYGTPELIFLDEPTTGLD
                     IQSRDDLWDAVDRLREDGSTVVLTTHYLEEAQQRADRIGLMHQGVFHREGTVSELTRTL
                     PATIRFSLPLSAPEPPPPAVGEGEGRFLIETPGLQKDLHVLLDWARDHAVELRDLQAGP
                     TRLDDVFRAIGEE"
     misc_feature    complement(6712..6726)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.8"
                     /tool="antismash"
     gene            6923..8035
                     /locus_tag="PWG71_RS08160"
                     /old_locus_tag="PWG71_08155"
     CDS             6923..8035
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017583330.1"
                     /locus_tag="PWG71_RS08160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_08155"
                     /product="histidine kinase"
                     /protein_id="WP_274808946.1"
                     /transl_table=11
                     /translation="MRESAQVKQELLRSLTLNLVSAALSAVGALLIANNAQSWEQSVVL
                     ALGLVAALVSVSGWAVGGLSRVVLSCLAVAAAVWTVGVLVMDESSASYGLSVVGTIVVL
                     RLPRHRRAAALGLVAVAVAVVAVRLSMESQDLLGVLVRYAVGSTSVAVTGFVLTFLGHL
                     VSGLITELEESREREAELAVARERVRFAGDLHDIQGHTLHVVKLKVALARKLLHGDIDR
                     VEGELGEVHALVGDTIAQTKELAYAQRRLNLSAELENAKNLFEAAGIDVRVDREAEVDA
                     RAAELLGQVLRETTTNILRHAQSERVRVTLSRAGIIIDNDGAPDNGPPELRGLSTLRER
                     LEREGGTLTVEQKDGRFLTAATLPQRKDDR"
     gene            8032..8634
                     /locus_tag="PWG71_RS08165"
                     /old_locus_tag="PWG71_08160"
     CDS             8032..8634
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020645900.1"
                     /locus_tag="PWG71_RS08165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_08160"
                     /product="response regulator transcription factor"
                     /protein_id="WP_274808947.1"
                     /transl_table=11
                     /translation="MTTVVLADDEALLRKALASLLPLEGEITVLAEAEDGERAVEATLR
                     HRPDVLVIDLEMPGVDGLGAVAEIRRELPDQVILMLTRHARPGVLRKALRLGVQGFVTK
                     SAEPSHIASVVATLHEGRRWVDPDVSALAVIDDCPLTDREVDVLRETGEGYSVAEIAGR
                     LHLAEGTVRNYLSNAMQKTQTRTRHEAARYAREHDWL"
     gene            complement(8819..9982)
                     /locus_tag="PWG71_RS08170"
                     /old_locus_tag="PWG71_08165"
     CDS             complement(8819..9982)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017583317.1"
                     /locus_tag="PWG71_RS08170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_08165"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_274808948.1"
                     /transl_table=11
                     /translation="MTCTPESMDALRLLGDELADATVEALFERGEVGKFNTLMRYFSTT
                     GQDLPDGLPDVAREYLRATATPPAWVDWGEVEKARLFFIDNNVHISTALAFSAMPACYV
                     IPHVAKLLSATHALEYPSRRMAETGQFTVYLMQPDAFEAGSRFVPAAQKVRLLHASIRY
                     HMRREGRWDVAALGTPICQEDMIGGQMMFSLQVLDALHRLGIHMSVEGAESYFYVWRIV
                     GEMLGIAPEHAPTDLDGARRFSDLYMTRHMGPSEEGARLTRQLIELYEEVVPGTLFDPV
                     VAALIRYLIGDTCADWLQVPRTGWDTAVKVSPALLGIFERIEDRSPMGAWALDHLGNLV
                     THLELSSLTRGRVMQYAIPERLKDEYGVTSTAHRTGRWTPPPLTPHT"
     gene            complement(10001..11053)
                     /locus_tag="PWG71_RS08175"
                     /old_locus_tag="PWG71_08170"
     CDS             complement(10001..11053)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017566077.1"
                     /locus_tag="PWG71_RS08175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_08170"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_274808949.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.6e-41, bitscore:
                     136.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSETEEQILLRTRVDSALREFARQETGRLLAIDADLTPVAEQLAV
                     AVADGKRLRAAFCYWGWRAAGQPDSDALVRAAAAMELVHAAAVIHDDLIDESPMRHGVP
                     SAHVALRAAFTDRARPQAGGRALALLTGDLLMSWAAQLFLFSGLPAAYLSRARELWSVM
                     TRELIAGECLEVLRTGSRPDTERSLQVIRYKTAKYTVEHPLRIGGAMAGAPGTLMEAFT
                     AYGLPLGEAFQLRDDLLGLFGDPRRTGKSNLDDVRGNRPTVLFAETWSAATAAERRELR
                     GLLGRRGLDGEGLSRVRAITRRTGALDRVEEMIAQRVQTATTVLAHADLPAEAAAALSH
                     MVASAASRRS"
     gene            complement(11046..11327)
                     /locus_tag="PWG71_RS08180"
                     /old_locus_tag="PWG71_08175"
     CDS             complement(11046..11327)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017584787.1"
                     /locus_tag="PWG71_RS08180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_08175"
                     /product="hypothetical protein"
                     /protein_id="WP_274808950.1"
                     /transl_table=11
                     /translation="MAHTGDGAKTDHVGESVLFAAGVADLAFSGVGAALRRARALLVRS
                     DLVELAHDGREELRQRGRLALRRYAPASESHLEQLARRAASRPGQSDV"
     misc_feature    complement(11761..11772)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    complement(11769..11782)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.26"
                     /tool="antismash"
     misc_feature    11770..11783
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 18.52"
                     /tool="antismash"
     misc_feature    11772..11785
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.23"
                     /tool="antismash"
     misc_feature    complement(11773..11786)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.28"
                     /tool="antismash"
     misc_feature    complement(11778..11791)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.99"
                     /tool="antismash"
     misc_feature    11799..11812
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.43"
                     /tool="antismash"
     gene            complement(12137..12871)
                     /locus_tag="PWG71_RS08185"
                     /old_locus_tag="PWG71_08180"
     CDS             complement(12137..12871)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PWG71_RS08185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PWG71_08180"
                     /product="hypothetical protein"
                     /protein_id="WP_274808951.1"
                     /transl_table=11
                     /translation="MSNDQDPWIACYRALLPWTRRFQEGDSHRAVRIAVERSLVTLWGG
                     LDPERPATDADVHAIVAACNAYHQGWFDAVIGTEARRTWPDGERWPFSLWVWQDSSRGH
                     GRGRAFRDTIGEHLDFFARFRFQSTLDLVGYAEHAARAATGAARQRAADAVVDVLEQAW
                     TRVDGWGWDDAGWYEYIEVEELVGWTMAALRIPGLIPSEAAERVYRIAEQGAWDGWSEW
                     SSKRPPAPFLAQAAQAVADCVR"
     gene            complement(12987..15482)
                     /locus_tag="PWG71_RS08190"
                     /old_locus_tag="PWG71_08185"
     CDS             complement(12987..15482)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013594.4"
                     /locus_tag="PWG71_RS08190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_08185"
                     /product="M48 family metalloprotease"
                     /protein_id="WP_274808952.1"
                     /transl_table=11
                     /translation="MLPSATSIRFSLIILVAAVGSMYIAFWFVPILPLLGADTTGSAAQ
                     AACADQARADVDRLSDQALLNDFVDCAAAKDRQVLLWMVAPGLVWAGLTIAVYALYPLL
                     LQRRLRPVRLSQDSGVRAAQREVDAVLDGSRKRLKLLTTPGTAGGARVFGAFGRYRIAV
                     DTSLLVPGESGGLDQRALAVIRHEAAHLRNRDVDITYLTMSSWWAFVLLNTGPLTLYVF
                     AALYSVVVLDSSTILLGNALPGLLLMAVALLLLQAARARVLRTREHYADVRAAEADQVE
                     EGLRDLLARAQRPQSSSRLRRWWRRRREYHPSHRSRLDVLDEPRRLTTVSGVDLAIAGL
                     ALSAAHLHLSAAGGIGLAQGSEGGVTTAVVVGAPVGALITAIVWNAVHSAPNGTRRWRR
                     TAAALTAGILLGLLPPVQLGVSWLALLVSNPLLAVVSVLMLWGLCLLFLRWAALCAGAW
                     LVTAGRQRAVCFVGMACGAAVFGCGFGIWVHFNGVLGAEADGGWVALLVAPVPVFMSGW
                     RFPAAVGCATVFAFIGLMRGSRVHGLDRHPLTPIVAGCALTGLYAALLLVAVAVGLAGG
                     SLSIVLILLLILLAAATVSVTLGAWFEGDGLRSTGPCLAAVAVLTLLALEPLVYAVMFE
                     GTVCLLTEAPSKCPGVTTRALLAGYAEAAFVQVGLPVLLLLCGTGASAGSWLRSMVGAH
                     GRTTDGWNPTVPWRRRNTVGALAAVAAATMILGSAVVTVVQNEAPRIDADVRPSLLSQV
                     EPAALSRDDTCTGAETSMDLRVHGTAPALLFNDAEAGAVTLASSGDPVLAAFGRAALGE
                     SGTPSGQLFDAVRSYCSSN"
     gene            complement(15529..16038)
                     /locus_tag="PWG71_RS08195"
                     /old_locus_tag="PWG71_08190"
     CDS             complement(15529..16038)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PWG71_RS08195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PWG71_08190"
                     /product="hypothetical protein"
                     /protein_id="WP_274808953.1"
                     /transl_table=11
                     /translation="MPEIPTPTGRSATIDDVARSVVARVAPDETSAYPRVRDEYFARGR
                     ANRAEDNPLGFGEVVIGVVAGIVLTVLHDLTVESLTAVARPWWKRAWQWVGRVLRVRRR
                     PKAGPDTVVRALSLEEAPAVIVSVNDHAVKAGLPPEQAERLAQAIIAELLSPDQPDGGV
                     GADSSG"
     misc_feature    16312..16325
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.51"
                     /tool="antismash"
     gene            <16854..16970
                     /locus_tag="PWG71_RS08200"
                     /old_locus_tag="PWG71_08195"
                     /pseudo=""
     CDS             <16854..16970
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185382.1"
                     /locus_tag="PWG71_RS08200"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_08195"
                     /product="IS110 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="RTAEGRAKREIIRCLKRYVIREVWHLLRPAPRAALTGS"
     misc_feature    16929..16931
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(17080..17098)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.8"
                     /tool="antismash"
     gene            17196..18503
                     /locus_tag="PWG71_RS08205"
                     /old_locus_tag="PWG71_08200"
     CDS             17196..18503
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1206: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013160159.1"
                     /locus_tag="PWG71_RS08205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PWG71_08200"
                     /product="ISL3 family transposase"
                     /protein_id="WP_274808954.1"
                     /transl_table=11
                     /translation="MDDTTFACPDLTTFCRLDDLGLEAVGQRLEPDRAVLLCRVVEPDE
                     WCRRCGCQGAPRDTVTRRPAHEPLGWRPTTLKVIVRRYRCTGCGHVWRQDTSKAAEPRA
                     GLSRRGLRWALEGIVVHHLTVARVAEGLGVSWNTANDAVLAEGKRVLIDDGHRFDGVKA
                     IGVDEHVWRHTRRGDKYVTVIIDLTGIREGTGPARLLDMVQGRSKQAFKTWLAERARAW
                     RDAVEIVAMDGFTGFKTAATEELPDAVAVMDPFHVVRPAGDALDRCRRRVQPAINGHRG
                     HKGDPLYSARRTLHTGADLLTAEQRDRLADLFATDEHVEVEATWGIYQRMITAYRHPDR
                     ARGRELMAALISSLGHGVPPPLTELVTLGRTLKKRAADVLAYFERPGTSNGPTEAINGR
                     LEHLRGSALGFRNLTNYIARSLLETGGFRPLLHPEM"
     misc_feature    18456..18458
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18617..18787
                     /locus_tag="PWG71_RS08210"
                     /old_locus_tag="PWG71_08205"
     CDS             18617..18787
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PWG71_RS08210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PWG71_08205"
                     /product="hypothetical protein"
                     /protein_id="WP_274808955.1"
                     /transl_table=11
                     /translation="MIKKIPGFLAALMALTLLAPPAQAHATHVLPAVAAEDYYAEINGV
                     EYRVSQERSQT"
     misc_feature    18630..18645
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.13"
                     /tool="antismash"
     misc_feature    complement(18831..18845)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.65"
                     /tool="antismash"
     gene            18923..19171
                     /locus_tag="PWG71_RS08215"
                     /old_locus_tag="PWG71_08210"
     CDS             18923..19171
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PWG71_RS08215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PWG71_08210"
                     /product="hypothetical protein"
                     /protein_id="WP_274808956.1"
                     /transl_table=11
                     /translation="MDDWNNIAVRIGDNWRSFADFAIEQILIAPESATYKSGNDTYAFT
                     APVQIRDGDGNVISTYRPIVSVANESRNIITAYPRRG"
     gene            19186..19545
                     /locus_tag="PWG71_RS08220"
                     /old_locus_tag="PWG71_08215"
     CDS             19186..19545
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PWG71_RS08220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PWG71_08215"
                     /product="hypothetical protein"
                     /protein_id="WP_274808957.1"
                     /transl_table=11
                     /translation="MDDTLLFAELVRRLNLDDGLADEAPDRMGVLVRRWQGRDLDPPYM
                     LHVDPPRLGEHLRSMEGISELFPDTASEIGGLRLFLVHIEEAVETAPEGHRHLLIGPAG
                     VYARPDAPPQTDRSV"
     gene            complement(20340..20987)
                     /locus_tag="PWG71_RS08225"
                     /old_locus_tag="PWG71_08220"
     CDS             complement(20340..20987)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PWG71_RS08225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PWG71_08220"
                     /product="hypothetical protein"
                     /protein_id="WP_274808958.1"
                     /transl_table=11
                     /translation="MSSWASRFGAWIEHLRRTRPVFHSKSDLVHSLARSIRACDPSLEV
                     HPGEGRGTERVDLRVSIPSLGAHLALRLRYPRAAWTETVAGERFALKNHGAQELTCYDV
                     VRDIRDLEQLTDRHLGWSGGVLLLTNDPLYWKRPDHDRPAIHDAFRLYEGAHLAGVRAW
                     RPYAGQGTTDKREEPLALRGAYRCTWSRYSGLEGHKGDFRLLTIPIGRRIPR"
ORIGIN
        1 atccgtgccg tcccctccct cggcccgggt cggaaccccg gcgcgcggtt cgtacggtgc
       61 gggcgcgggc tcgccctccg ggctttccga caccgtcggc cgtgacgggt tccggacggt
      121 ggtgccggcc ggcgggacca cgacggtcgt taccggccac gcgctttcca ggccgtggtg
      181 ttcgaagcgg gtgaggatct gctcgggtgt ggggcgttgg gcggggtcgt ggttccagca
      241 gtgggtgatc aggtcccgga tgtgggggtc gatgtcgccg gggtcggggg gtggtgagat
      301 caggcggcgc agggtctcgg ccatggtggt gccggagaag ggcccggtgc cggtggcggc
      361 gtaggccagc acggtgccca gcgagaacac gtccgaggcc gggcccaccc gtgagccgtc
      421 ggtctgttcg ggggacatgt agggcagggt gccgaacacc gcgccccggg tggtcatgct
      481 gtcggcgtcc acgggacggg cgatgccgaa gtcgatgatc ctggggccgt cctcggccag
      541 gatgatgttg gccggtttga ggtcgcggtg gaccaggccg caggcgtgga tcgcctggag
      601 accctcggtg aggccggtgg ccaggacgtg gagcacgggc ggggcgaggg ggccgtccgc
      661 ccggacggcc tgctccaggg tgggtccgtt gatgtgggcg gtggcgatcc agggggagtc
      721 ggcgtcgggg tcggcgtcca cgacctgggc ggtgtggaag cccccgaccc ggcgggcggc
      781 ctcggcctcc cgggcgaacc gggcgcggaa accctcctcc ccggcgagtt cgggatggac
      841 gaccttgacg acgagcagtc gtcccgaggt ggtgcgggcg aggtagaccc ggcccatacc
      901 gcccgcgccc aggcgtgccg tgagtcggta cccgccgatg cgcggcgggt cggtgggatg
      961 gaggggttcc acggcgtcgg cctcttgtcg gatggggaag agcggtcggg tgatcttccg
     1021 ggactggtcg gtgtcgcggg tgggagcggt ccgtggaccg ctcgccgtta ccggggccgc
     1081 cacggggagg gacggggccc gcttcgaaca cggtacggat tctggtgtgc gaacccgcgc
     1141 ggggtaaggg gtcgcgacct catcggccac atccggccgt cgaggcggcc gaggacgggc
     1201 cccggcgcac acatgacgat gccaggcgga tcgcgggcgt tcggggccgg ggccgaccct
     1261 gggggagcac cccgcccgga tgggttcctg gaaacggcgg gacgggatcg gcatcggccc
     1321 tggcagccgg tcatgggtgg cggatagtgc cggagtggtg accatgtgtg tattcaccgc
     1381 ctgggttccg tgtgctaata ctgataatcg ttttcatcaa gtcatcgccc gtcgcccccg
     1441 gctcgggtgc cggcgggatg ggcagtgcga acgcggggct cgtcggatca tgggcggcct
     1501 cggtgatcga ccgaagggaa aacgaccgtg cattcaccgt cctctccggc caacaggacc
     1561 ggcacaccgg tccgaccggg cgccgccacc ggctgggagc tgcacggatt gctgccacag
     1621 acgctgtccg ccgaggagat ccgggcgatc aacgaccccg gccgggccat ccacgagcac
     1681 cgcgcctaca cctggaacgg ctgggacttc gacctgccgc cgggtgtgtt ccacccgggt
     1741 gagaccagcc gactggtgca cacccggttg ctcgacggga cgctgccggt cgccggcctg
     1801 cgctacgccg cgatgggtgc gggcctgggc gtggaggccg tggtggccgg agtccgtggc
     1861 gcgagcgtcg tctacgcgct ggacgtgcat ccggagagcg tgcgcaccac cacccggcac
     1921 tacgagcgga tcgtcggcgc ggacggacca ccactggtcc cactcgtgac cgacgtgtgg
     1981 gagggattcc ccggcgggga gcaggtggac gtcgtcacgt tcaacccgcc ggccatcgaa
     2041 ctgccgctgt cggacgatcc ggagatcgtg cgcaacctgt gcctgggccg cgacatcgcg
     2101 acccggttct tcgaccagtt ggtggccagg gacctgctcg ccgccggcgg agtggtgtac
     2161 ctgatcctgt cgaacaccgc accgctgcgc gacatcgtgg cgctgggcct gcgggccggg
     2221 ttcgacgcgg aggtcgtgca cgtcgaggac tggcccggcg atgacgtgca gacctatctg
     2281 ttcgccttgc gccgcccggg cggtcgtccc ggtggggagg actgagcacc gtgcacgagc
     2341 actacgcgga cgccatcgcg gaccccgatt gcatccggct cgctcccgac ctggtctgcc
     2401 tgcggttcga ggtgatgaag gtgcgttcgg ccttgggcgc cgtgcgtcat ctgctggaca
     2461 cgggggcggt gcgccccggc gacacactgg tggacagctc cagcggcatc tacgcactgg
     2521 ccctcgcgct ggcctgccac cggtacggga tgcgctgcca catcgtgggc tccagcacgg
     2581 tggacgagac gttgcgggta cagctggagg tcctgggcgc gaccctcgaa cagatgccgc
     2641 cgtcggacga cctgatgctg gaccagaacc ggcgggtcga gcgggtcggg aggctgctgc
     2701 tggagaaccc cggtttccac tggatgcgcc agtaccatga cgcgatccac tacgtcggct
     2761 accgcgaggt ggccgaacag ctcgaccgag aggtgccgac cgggccgctg accatcgtca
     2821 gcggtgtggg caccggctcc tcgaccggcg ccctgggctg ctacctgcgg gcggcgggac
     2881 gggacgtgga gctggtcggc atccagccct tcggcagcgt caccttcaac gccgagcaca
     2941 ccgccgaccc cgacatgatc atcgccggta tcggcagctc gatcgagttc cgcaacgtgc
     3001 gccacgaact gtacgaccgg atccactggg tctcgttcga gtacgcgcga gcaggcgcgg
     3061 tggccttgct gagggacagc ggcgtgttcg ccgggctgtc cgccggagcg gcctacctgg
     3121 ccgcggggtg ggagggcggg cgcacggcgg ggcgcaccgt ggtgttcctc gctccggaca
     3181 cgggtcaccg ctacgtccgc gcggccttcg cggcgcacgc gcacgtcccc ggcatcgccg
     3241 atctgtcacc gcacgaggtg gccgacagcg acgggatcgc gctgccctgg tcggtcgccg
     3301 accgcacggc cctgtccgcc tcgtggcggg acgccgtacc ggtggccgtc cgcgcaccga
     3361 gcggatcccc ctgacccgcc ggcaccggac gtcgccgcgg catccctccc cgcggccgcg
     3421 cccgttcgtc ggccacgccg atgccccggg gggcgggcgc caccggcccg cccccggacc
     3481 acccccgccg ggtcggcgtc cgcggtggat caggccgggc cggtgaaccc ggtgaagagc
     3541 acgagcaggg gcagggcgag gttgttgacg gagtggacgg ccaccgcggg ccagaccgaa
     3601 ccgctgcgac gcatcacctc ggcggcgatg acgcccacca cgaacgcggc gggcaggatg
     3661 atgttgacgc cgtggaagac ggcgaagatc gccgagccgc cgaggacccc gacgaccggc
     3721 ccgtagcgca gcaaggcgtt ggtgacgaca ccgcggaaga ggaactcctc gccgatgggg
     3781 gtcagcacgg ccaggaacag gatggtcagg accagggcga gcccgcctcc gccggccgcg
     3841 tcgtagtaca tgccctgggg gtcgtcgtcg aacccggtca gcgcggtgat ggcgaggatc
     3901 acggcgccct tcacgacgag cgcgaccacg ccccaccccg cgccgatgag catccagcgc
     3961 cacgtggtgc gacgaacccc gaaggcgccg agcgagcgga cgcgcaccgc ccaggccgcg
     4021 gcgaagccga cgagcccggc gatgcccgac caggcggccg tgatgagccc gaacgtcacc
     4081 gggtccgggt ccaggggacc ggccggcccg aggaggacga gcgcgaccac ggtgatcgac
     4141 agcgcgagca ggccgaccac gatctcggtc caccccggtc gcaccgggga ggcgtcgccg
     4201 acggcgtcgt ggttctgcgg acgggcgggg tgatccgtgg acatgacggt ggactccctg
     4261 ttctccggat ctcgtcgatc gccccgccgg gatccggcgt ggcgtggtgt cgggtcggta
     4321 cggctaggag gtgccggccc tgcggttcac gaccgccgtg aggatcgcgt tgagcatccc
     4381 ggggacctcg gcctcgaaac gttcgcggag cgccttgacc tcggcccggt gccgctgacg
     4441 ctccgccggc gtgaacaccg tccagacgtc cccctcgacc gcgatcgcgg ccagggccgc
     4501 gtcctcgatg gggaccgagg ccgcctcgcg gcccgcgagg accgcgtcgc gcgtgcgctc
     4561 gcgcagcaga cggacccgtt cggggtggtc gagggtgacc ttgcgggagg ggaacatccc
     4621 cagcacccgg cctcggacca cggtgatcga cccgttcgcg acgagctgct cgcggacggt
     4681 cgtctcggcc ttccactccc ggtccgggac ggcgttgatc caatggcccg gttcgttcgg
     4741 ggacagaccg gacagcacgt cggccaggaa cgggtcgtcc ggcgtccggc cggtgcgctc
     4801 ggccctgccg ccgttgtcgc ggagcaggcc gccgatgatc agctcggtca gcgccgcggc
     4861 gcgcagcaga tgcccccggt agggggtgct gacggggtcg aaccggttcc cgtcgatgtc
     4921 gtaggtgagc aggtagagcc gttgtggcag ggtcatgtcc atggtgcccc tctcgggttc
     4981 ctcgggatcc gttccgtgtg gagcacgccc tcggcccggg cgtccgccga ctcgcgtcga
     5041 tacttccgtg tccgcaccgc gctcacccga acgtccacgg gcgtgtcgcc gaggccgtca
     5101 gcggcggggc tcccaccgga agatccgggc ggccagaccg acggcgacga cgacccaggc
     5161 cagggtgggc gccagcagga acagggagtc cgcgaccggg acgccgccgt cccaggcgtc
     5221 gacgaccagc tccgccgccg ccccgccggg gagcagccgc ttgagcaggg tgagctcctc
     5281 ggttccggtg aaccccaccc agccggacac gacgagcacg ccgagaagga cgggcagggt
     5341 ggtcacctgg gcgtgttcgg gcgagttggt caccccggcc gtggccagcg ccaggccgag
     5401 catcatgacg accgtcgcga gtgtggccgc caccaggagc aggaggtcgg ccggcggttc
     5461 ggcgacgatc gacagcacgg tcaggaccac ggccacctgg acgaccgtga tggcggtgac
     5521 cgggagcagc agcccggtga ggatgcgcgc gtcgtccacc gcggtcgagc gcagccgctt
     5581 gaggaagagg ttctggcggc gggaggcgag cgtggtcacc gctgtggtgt agagccccat
     5641 caccaccacg aggaacatca gtacagcggc caccgtgccg agggccagcc cggggatgcg
     5701 atcgtgcagg tagatgtaga acgcactggc cgccgcgggc atgacgagca tggtgaccag
     5761 taccagccgg ttacggaaga tctggatcag ctcaccgtga gcgatcgcga gcatggcgaa
     5821 ggtccctttt cctggaggtt tcgaaagagc gggcgatgag gggacgcgcg gtctactcct
     5881 cgccgatggc gcggaagacg tcgtcgagcc gggtcggtcc ggcctggagg tcccgcagct
     5941 ccaccgcgtg gtcccgcgcc cagtccagga ggacgtgcag gtccttctgg agaccggggg
     6001 tctcgatgag gaacctgccc tcgccctcgc ccacggccgg cggtggcggc tcgggcgcgg
     6061 agagcggaag ggagaagcgg atggtggcgg gcagcgtccg cgtgagttcg gagacggtcc
     6121 cctcccggtg gaacaccccc tggtgcatga gcccgatacg gtcggcgcgc tgctgggcct
     6181 cctccaggta gtgcgtggtg agcacgacgg tggagccgtc ctcgcgcagc cggtccacgg
     6241 cgtcccacag gtcgtcccgg gattggatgt ccagaccggt ggtgggctcg tccaggaaga
     6301 tcagctccgg cgttccgtac acggcggtgg cgaagtccag ccgccgcttc tctccgccgg
     6361 agagccggga caccctggtg tcggccttgt gttcgaggcc gacgacgccg agcaggcgct
     6421 cgacccggtc ggtgcgccgg gtgagccctc cgatcagccg gatcgactcc cgcaccgtca
     6481 ggtccgggga gaaaccgctc tcctggagca tgatccccgt ccggggccgc acggacccgc
     6541 ggtcgcgcgg gtcgcgtccg aagacccgca ccgtgccgga cgtggcgggt cggtggccct
     6601 cgacggtctc cagggtcgag gtcttgcccg ccccgttcgt gccgagcagg gcgtacaact
     6661 ccccgcgccg tacctggaag gacaggtcct tcacggcgtg gaaatcgccg tatctcacat
     6721 tcagacgttc gacgtcgatg accggtgtag aggacatgtc accattccag ccgtcggcgc
     6781 tcccgtccgg cagtgcggtc acgtcaccac tccgccatga cttttccccg tgtgaggtca
     6841 tgacgtggcg tcactggtgg cgcggcgaag ctgggagaat cctgggacgg accccgcagc
     6901 ccgacaccgg agggccccat ccgtgcgcga atccgcccag gtcaagcaag agctcctgcg
     6961 cagtctcacc ctcaacctcg tgtccgctgc gctctccgcc gtgggcgcgc tcctgatcgc
     7021 gaacaacgcc cagagctggg aacagtccgt cgtcctggcg ctgggtctgg tggccgccct
     7081 ggtgtccgtc tccgggtggg ccgtgggggg cctctcccgt gtggtgctct cctgcctggc
     7141 cgtcgccgcg gccgtgtgga ccgtcggagt gctggtgatg gacgagtcct ccgcctccta
     7201 cggcctctca gtggtgggca ccatcgtcgt cctccggctg ccgcgccacc gccgggcggc
     7261 ggctctgggg ctggtcgccg tcgccgtcgc cgtggtcgcg gtgcggctgt cgatggagtc
     7321 ccaggacctt ctcggggtgc tggtccggta cgccgtcggc tccacgagcg tcgccgtgac
     7381 gggattcgtc ctcaccttcc tcggccacct ggtctccggc ctcatcacgg agctggagga
     7441 gtcgagggaa cgcgaggccg agctggccgt ggcccgggaa cgcgtgcgtt tcgccggtga
     7501 cctgcacgac atccagggcc acaccctgca cgtggtgaag ctgaaggtcg ccctcgcccg
     7561 gaagttgctg cacggcgaca tcgaccgggt ggagggggaa ctgggcgagg tgcacgccct
     7621 ggtcggcgac accatcgccc agaccaagga gctggcctac gcgcagcggc ggctcaacct
     7681 gtccgcggag ctggagaacg ccaagaacct cttcgaggcc gcgggcatcg acgtccgcgt
     7741 cgaccgcgag gccgaggtcg acgcccgcgc ggccgagctc ctcggccagg tcctgcggga
     7801 gacgacgacc aacatcctgc ggcacgccca gtccgagcgg gtgcgggtca ccctctccag
     7861 ggcgggcatc atcatcgaca acgacggcgc gccggacaac ggaccgcccg aactccgggg
     7921 actctccacc ctccgggagc ggctggaacg cgaaggcggc acactcacgg tggagcagaa
     7981 ggacgggcgg ttcctgaccg ccgcgacatt gccgcagcgg aaggacgacc gatgaccacc
     8041 gtggtgctcg ccgacgacga ggcactcctc cgcaaggcgc tggcctcgtt gctccccctg
     8101 gagggcgaga tcaccgtgct cgccgaggcc gaggacggtg agcgggccgt ggaggccacc
     8161 ctgcgccacc gccccgacgt gctcgtcatc gacctggaga tgcccggcgt ggacggactc
     8221 ggcgccgtcg cggagatccg ccgtgagctg ccggaccagg tgatcctgat gctgacccgc
     8281 cacgcccggc ccggcgtgct ccgcaaggcg ctcagactcg gcgtccaggg attcgtcacc
     8341 aagtcggcgg agccgtcgca catcgcctcc gtcgtcgcga ccctgcacga gggcaggcgg
     8401 tgggtcgatc ccgacgtgtc cgcgctcgcc gtcatcgacg actgcccgct caccgaccgg
     8461 gaggtcgacg tcctgcggga gaccggcgag gggtactccg tcgcggagat cgccggtcgc
     8521 ctccacctgg cggagggcac ggtgcgcaac tacctgtcca acgcgatgca gaagacccag
     8581 acccgcaccc ggcacgaggc ggcgcggtac gcacgcgagc acgactggct gtaggggtcc
     8641 cggcccggcc ccggcgggtg cggttcgtgc cccggtgcgg tcggcggatt cccacggtca
     8701 tcgcgatgcg ccgagtcggt cggccgccac tcggagctct gggagacgct cggccgagcg
     8761 tctcccaggg ctccgtcccg tgtcgggtgc gatggaggac cgcgcctgtc ggagtcgctc
     8821 aggtgtgggg cgtcaggggc ggtggagtcc agcggccggt gcgatgggcg gtggaggtga
     8881 cgccgtactc gtccttgagc cgctcgggga tggcgtactg catgacccgg ccacgggtga
     8941 gagagctgag ttccaggtgg gtgacgaggt tgccgaggtg atccagggcc cacgccccca
     9001 tcggagagcg gtcctcgatg cgctcgaaga ttccgagcag ggcgggggag accttgacgg
     9061 ccgtgtccca gccggtccgc gggacctgga gccagtcggc gcaggtgtcg ccgatgagat
     9121 agcggatgag agcggcgacc acggggtcga agagggttcc ggggacgacc tcctcgtaga
     9181 gttcgatgag ctggcgggtc agccgtgccc cctcttcgga gggacccatg tgcctggtca
     9241 tgtacaggtc ggagaaccgc cgggcgccgt ccagatcggt cggggcgtgt tcgggggcga
     9301 taccgagcat ctcgccgacg atgcgccaga cgtagaagta ggactccgcg ccctcgaccg
     9361 acatgtggat gcccaggcgg tgcagtgcgt ccaggacctg gagggagaac atcatctggc
     9421 cgccgatcat gtcctcctga cagatcgggg tgccgagcgc ggccacgtcc caccggccct
     9481 cacggcgcat gtggtagcgg atggaggcgt gcagcagacg caccttctgg gccgccggga
     9541 cgaagcggct ccccgcctcg aaggcgtcgg gctgcatcag gtagacggtg aactgcccgg
     9601 tctcggccat gcgccgcgag gggtactcca gggcgtgggt ggcgctgagc agcttggcca
     9661 cgtgcgggat gacgtagcag gcgggcatcg cggagaaggc cagggcggtg gagatgtgca
     9721 cgttgttgtc gatgaagaac agccgggcct tctccacctc accccagtcg acccaggccg
     9781 gcggtgtggc ggtggcgcgc agatattcgc gggcgacgtc cggtagcccg tcgggcagat
     9841 cctgacccgt cgtggagaag tagcgcatga gggtgttgaa cttgccgacc tccccgcgtt
     9901 cgaagagcgc ctccaccgtc gcgtcggcga gttcgtcccc caggagacgc agcgcgtcca
     9961 tggactccgg tgtgcaggtc atgggatctc cttctacggg tcaggaccgg cgggacgcgg
    10021 ccgaggccac catgtgggac agcgcggcgg cggcctcggc cggtaggtcc gcgtgggcga
    10081 gaacggtggt cgcggtctgg acgcgctggg cgatcatctc ctcgacacgg tcgagggccc
    10141 cggtgcgtcg cgtgatcgcc cgcactctcg acaggccctc accgtccagg ccgcgtcggc
    10201 cgagcagacc gcgcagctcc cggcgttcgg ccgcggtggc ggccgaccag gtctcggcga
    10261 acaggacggt cggccggttg ccccggacgt cgtccaggtt cgacttgccc gtgcgtcgcg
    10321 gatcgccgaa gagccccagc aggtcgtccc gcagctggaa cgcctccccc aggggaagcc
    10381 cgtaggcggt gaaggcctcc atcagcgtgc ccggagcacc ggccatcgcg ccaccgatgc
    10441 gcaggggatg ctcgaccgtg tacttggcgg tcttgtatcg gatcacctgg agcgatcttt
    10501 ccgtgtccgg ccgggagccg gtgcgcagga cctccaggca ctctccggcg atcagctccc
    10561 tggtcatgac cgaccacagc tcgcgggcgc gggacaggta ggccgcgggc aggccggaga
    10621 agaggaacag ctgcgcggcc cacgacatca gcaggtcccc ggtcagcagg gccagggcgc
    10681 ggcccccggc ctgaggacga gccctgtcgg tgaacgcggc gcgcagcgcg acatgggcac
    10741 tcggtacccc gtgccgcatc gggctctcgt cgatgaggtc gtcgtggatg acggccgccg
    10801 cgtgcaccag ctccatcgcc gcggcggccc tgaccagcgc gtcgctgtcc ggctgcccgg
    10861 ccgcgcgcca tccccagtag cagaaggcgg cgcgcaggcg cttgccgtcg gcgaccgcca
    10921 cggccaactg ctcggccacc ggcgtcaggt cggcgtcgat ggcgagcagc cggcccgtct
    10981 cctgtcgtgc gaactcccgc aacgcggagt ccacccgggt acggagcagg atctgctcct
    11041 cggtctcaga catcgctctg accgggccgg gaggcggccc gtcgggcgag ctgttccagg
    11101 tgggactcgg acgcgggcgc gtaccgtcgc agcgccagcc ggccccgctg cctcagttcc
    11161 tcccggccgt cgtgggccag ctcgaccagg tccgaccgga ccagcagcgc cctcgctctc
    11221 cgcagggccg ctccgacacc gctgaacgcc aggtcggcca ccccggccgc gaacagcacc
    11281 gactcgccca cgtggtcggt cttcgcaccg tcaccggtgt gcgccacggc atccccatct
    11341 ccagatcgac acgaaaagga ccgcggcgaa gaaacggacg aaagctccgg atgaaacttt
    11401 gtccgggcat tcggatatcc gtcccgggtc cctgccgatt gatcatcttc tgcaatcacc
    11461 gcttttgtca atgcgatgat gggatctggt tcgctttggc ggcgttcggc ggagggggaa
    11521 tgcgaaagaa gcggacaatt cgaagagaag ggaggctcgg gtgtgggagg gcccggggcg
    11581 gcccgtgtcc ccgcgaagat gacgccgccc gatgcctcag gggtcgtcgc gcctgatcag
    11641 ggttcacgtc agggcggatg ccacgggagg cgtgtccgaa acatgcgggg gaggccgcgt
    11701 cccggaccgg cgcgatcgag ggagggggtg atgcggaccg cgcggatcct ttccggattc
    11761 gcgttcactt ttatgtatta taaaagcgat atgggagatt taattgtttt cgtgtgttat
    11821 gttcgctctg ggtcccccct gaagccgctg tgcggaaatg ggatcggacg agcgccggat
    11881 gggtgcgcat ccaggacatc ggtgggacct gtcggtgatg accgcccgcg tgtgcccggt
    11941 ggtgtgcgcg gccttcggaa ccggtcactt ccgcgaccat cgcacgccgg actcgggcgg
    12001 attcgcccga gcgggttcga cccctgtcgg gcgggggaga ggtccaccgg ggccgaggag
    12061 gacgagtcgg tctcgacctc gcagacctcg acggggccgt ggtcggtggt tcccctgggg
    12121 aacgcatccc gggacactag cgcacacagt ccgccacggc ctgtgccgcc tgggcgagga
    12181 acggagccgg cggtctcttc gacgaccatt ccgaccagcc gtcccaggcg ccctgctcag
    12241 cgatccggta cacccgctcg gcggcctcgg acgggatcag cccgggaatc cgcagggccg
    12301 ccatcgtcca gccgaccagc tcttccacct cgatgtactc gtaccagccg gcgtcatccc
    12361 agccccatcc gtcgacccgg gtccaggcct gctccagcac atccacaacg gcgtcagccg
    12421 cccgctgccg ggcggcaccc gtcgccgccc gggcagcgtg ctcggcgtac ccgaccaagt
    12481 ccaacgtgga ctggaaccgg aatctcgcga agaagtcgag gtgctcgccg atcgtgtcgc
    12541 gaaaggccct gccccggcca tggccgcgcg aggagtcctg ccatacccac aacgaaaacg
    12601 gccagcgctc cccgtcgggc caggtgcggc gggcctcggt gccgatcacg gcgtcgaacc
    12661 agccctggtg gtaagcgttg caggcggcga cgatcgcgtg cacgtcagcg tcggtcgccg
    12721 gtctttccgg gtctagccca ccccacagcg tgacaagcga gcgttccacg gcgatcctca
    12781 ccgcgcggtg cgaatctccc tcttggaaac gcctcgtcca cggcagcagc gcgcgatagc
    12841 aggcgatcca aggatcctgg tcgttggaca tcggggtaca gaccaacttc ttccatgccc
    12901 ggttgatcgg gggctctggt gtgtgccggg atcgcctccc ggcacacacc agagcctcca
    12961 tcacactttg cgcaggacac ccgctgtcag ttcgaagagc agtaggagcg caccgcgtcg
    13021 aacagttgtc cgctgggggt gccggattcg cccagcgcgg cccggccgaa ggcggccagg
    13081 acgggatcgc cgctcgaggc caaggtgacg gctccggcct cggcatcgtt gaacagtagc
    13141 gcaggtgcgg tgccgtggac cctcagatcc atgctggtct cggcgccggt gcaggtgtcg
    13201 tcccggctca gagccgcagg ttccacctga gagagcaggg acggccgcac gtcggcgtcg
    13261 atacgcggcg cctcattctg gacgacggtg accaccgccg aaccaagaat catcgtggct
    13321 gccgcgaccg ccgccaaggc cccgacggtg ttccgccttc gccaaggaac ggtggggttc
    13381 catccgtcgg ttgtgcgccc gtgcgctcca accatcgaac gcagccacga gccggcggac
    13441 gcccctgtgc cgcacaagag cagcaggacg ggcaagccaa cctggacaaa ggccgcctcg
    13501 gcgtatccgg ccagcagggc ccgcgtcgtg acacccgggc acttcgaggg cgcctccgtc
    13561 agaaggcaca cagttccctc gaacatcacg gcgtagacga ggggctccaa cgccaacagc
    13621 gtgagcacag ccacggcggc caggcagggc cccgtgctcc ggaggccgtc tccctcgaac
    13681 catgccccca gggtgacgct cacggtcgct gcggccagca ggatcaagag caggatgagg
    13741 acgatggaca gggatccccc agcgaggccc acggcgaccg cgaccaggag aagggccgcg
    13801 tacaggcccg tgagagcaca cccggccacg atgggcgtga gggggtggcg gtccagccca
    13861 tgtacgcgtg atccgcgcat caggccgatg aaggcgaaca cggttgcaca gccaacggcc
    13921 gctggaaagc gccagcccga catgaacacg gggaccgggg ctaccaacag ggcaacccag
    13981 cctccgtcgg cctcagcccc gaggactccg ttgaaatgga cccatatccc gaatccgcag
    14041 ccgaacacgg ccgctccgca ggccatcccc acgaagcaca ccgctcgctg gcgtccggcg
    14101 gtgaccagcc atgctcccgc gcacagcgcg gcccacctca ggaacagcag acacagcccc
    14161 cacagcatga ggaccgaaac cacggccaac agggggttgg acaccagcaa agcaagccag
    14221 gagaccccga gttgaacagg cggcaggaga ccaagaagga tgccagccgt cagcgctgcg
    14281 gccgtccttc tccagcggcg agtaccgttc ggggccgagt ggaccgcatt ccatacgatc
    14341 gctgtgatga gggcgcctac cggcgcgccc acgaccacgg ctgtggtgac acccccctcc
    14401 gagccttggg cgaggccgat gccacctgcg gcgctcagat gcaggtgggc ggcgctcagc
    14461 gccaggcccg cgatggccag gtcgacaccg ctgaccgtgg tgagccgtct cggttcgtcg
    14521 agcacgtcca accgggagcg gtgggaaggg tggtactcgc gtcgtctgcg ccaccatcgt
    14581 cgcaaccggg agcttgactg cgggcgctgt gctcgggcca ggaggtcgcg tagaccctcc
    14641 tcgacctgat cggcttccgc cgcgcgcacg tcggcgtaat gctcacgtgt gcgcaggacc
    14701 cgggcccggg ccgcttgcag cagcagaagg gcgacggcca tgagaagcaa ccccggtagt
    14761 gcattgccga gcaagatggt cgaggagtcg aggacgacga ccgaatagag ggcggcgaac
    14821 acgtagaggg tcagggggcc ggtgttcaga aggacgaacg cccaccatga ggacatcgtc
    14881 aggtacgtga tgtcgacgtc ccggttgcgc aggtgggccg cctcgtgccg gatcaccgcc
    14941 agggcacgct ggtcgagccc tccgctctcc cccgggacga gcaaggaggt gtcgacggct
    15001 atgcgatacc ggccgaacgc gccgaacaca cgcgccccgc ccgcggttcc cggagtggtg
    15061 aggagcttga gccgcttgcg ggaaccatcc aggactgcgt ccacctcccg ttgggccgcc
    15121 cgcactccgc tgtcctgcga gagtcggacc gggcgcagcc gcctctggag aaggagcggg
    15181 tacagcgcgt atacggcgat cgtcaggccc gcccacacaa gcccgggggc gaccatccac
    15241 agcaggacct gacggtcctt ggctgcggca cagtcgacga agtcgttgag gagggcctgg
    15301 tcggaaagcc ggtcgacgtc tgcgcgcgcc tggtcggcgc aggccgcttg ggcggcgcta
    15361 ccggtcgtgt ccgcgccgag gagcggcagg atcggcacga accagaacgc gatgtacatg
    15421 gatcccaccg cggcgaccag gatgatcagg gagaaccgga tactggtcgc gctgggcagc
    15481 aagaacggat cgtagcgtcg agggcttccg ggaacggtgc ccgtggtctc agccagagga
    15541 gtccgcaccg acaccgccat cgggctgatc cggggacaag agttcggcga tgatcgcctg
    15601 tgccagccgc tccgcttgtt ccggcggtag acctgccttc acagcgtggt cgttgacgga
    15661 cacgataacg gccggggcct cctccagaga cagggcacgc acgacggtat cgggtccggc
    15721 cttcgggcgc ctccgaaccc gcagcacccg ccccacccac tgccaggccc gtttccacca
    15781 cggccgggcc acggcggtga gcgattcgac cgtcagatcg tggagcacgg tgagcacaat
    15841 gccagcgacg accccgatga cgacttcgcc gaacccgagc gggttgtcct ccgcacggtt
    15901 ggctctgccg cgcgcgaagt actcgtcgcg gacgcgcggg taagcggagg tctcgtccgg
    15961 agcgacacgg gccacaaccg accttgccac gtcgtcgatg gtggcggatc gccctgtggg
    16021 ggtagggatc tcgggcaccg agcatgtcct ctcagcctct gtcctgaaat cggacgctca
    16081 ggctacgtcc ccagcactaa ccgtgtcagc aaaaggcgct ccttggcaca atccggccat
    16141 ggggtcatag cccctgagct ttctaatccg atggccgcag gtgcgaatcc tgccgggtgg
    16201 tgtgtcctgc gttcttcgga gtcgaatttc tggatcctgg gaccacgtga cccttgaagg
    16261 agggcatcgt gggacgtcgt ggataccccg ccgagttccg ccgcaaggtg ctggacctgg
    16321 tccaggccgg acgtagcgtc gcggacgtgg cacgcgatct gggcatcagc actgagacga
    16381 tctacgcctg gcggcgccag gaccgtatcg accgaggtct ggccccgggc ctgaccagca
    16441 ccgagaagac cgaactggcc gcagccaaca agcgcatcgt cgaactggag gccgaaccgg
    16501 ccatccaccg ccgggccact gagctgctgg ggaaggtggt gccccaaaag acggttcgag
    16561 gcgatcacgg tgatggccgc cgagggacat ccggtccagg tcgccgtccg ggtcctgggg
    16621 gtatcggagt cggggttcta cgcctggcgc gaccgcggac cctcggcccg ctcgatccga
    16681 cacgtgctgc tcaccgacac catccgccag atccacgccg cgtccaacgg cgtctacggg
    16741 gtgcggcggg tgcacaagga gtccggcctg gtgccctcga tgggatcgat cggggactgc
    16801 tacgactgtc agtcttcttg caccggatcc cgcaaggatc gggtagtccc ggccgcaccg
    16861 ccgagggcag ggccaaacgc gagatcatcc ggtgcctcaa gcggtatgtc atccgcgagg
    16921 tctggcattt actccgccca gcaccccgag cagctcttac cgggagttga caactatagg
    16981 agcgtcaatg ccgtcatcga gtcgttctgg tcgcgcatgc aggtcgagtt gctggatcgg
    17041 cgcaggtggc gaactcgttt ggagttggcc aacgcgatct ttgagggctc ttcgcagttg
    17101 agggtgtagc gccggtgggc gggtcggtcc cgggatagac gtcgaggtct cccgaggatg
    17161 gaagttctca cactgcccat ccggaagacc tcgacgtgga tgacactacc ttcgcgtgcc
    17221 ctgacctgac cacgttctgc cgtctcgacg acctcggtct tgaggctgtg gggcagcgtc
    17281 tcgaacccga tcgagcggtg ctcctgtgcc gggtcgtcga gcccgatgag tggtgccgcc
    17341 gctgcggctg ccaaggcgca ccgcgtgaca ccgtgactcg acggccggca cacgagccgc
    17401 tcggatggcg acccacgacg ttgaaggtca tcgtgcgccg ctaccgatgc accggctgcg
    17461 ggcacgtgtg gcgccaagac acttcgaagg ccgcggaacc acgggccggt ctgtcgcgcc
    17521 gcggactgcg gtgggcactg gaagggatcg tggtccacca cctgaccgtc gcccgggtcg
    17581 ccgaagggct cggggtctcc tggaacaccg ccaacgacgc ggtcctcgcc gagggcaagc
    17641 gggtcctgat cgatgacggg caccggttcg acggtgtcaa ggccatcggg gtcgatgagc
    17701 acgtgtggcg tcacacccgc cgcggcgaca agtacgtcac cgtgatcatc gacctgaccg
    17761 gcatccgtga gggaaccgga ccggcccgcc tgctcgacat ggtccagggc cgctccaagc
    17821 aagcgttcaa gacctggcta gccgagcggg cccgggcctg gcgcgacgcc gtcgagatcg
    17881 tcgcgatgga cggcttcacc ggtttcaaga ccgccgccac cgaagagctg cccgacgccg
    17941 tggcggtgat ggaccccttc cacgtggtcc gcccggccgg cgatgccctc gaccggtgcc
    18001 gacgccgggt ccaaccggcg atcaacggcc accgcggcca caagggtgac ccgctctact
    18061 ccgcgcgccg gaccctgcac accggcgccg atctgctcac cgctgagcag agggatcggc
    18121 tcgcggacct gttcgcgacc gatgaacacg tcgaggtcga agcgacctgg ggcatctacc
    18181 agcggatgat caccgcctac cgccaccccg accgggcccg cggccgagaa ctcatggccg
    18241 ccctgatcag ctcgctcggc cacggcgtcc cgcccccgct cacagagctc gtcacgctcg
    18301 gtcggacact gaagaagcgg gccgccgacg tgctcgcgta cttcgaacgc cccggtacca
    18361 gcaacggtcc gaccgaggcg atcaacggcc gcctggagca tctgcgcggt tccgcgctgg
    18421 ggtttcgcaa cctcaccaac tacatcgccc ggtcgttact ggagaccggc gggttcaggc
    18481 cgcttctaca ccctgaaatg tgatgagccg gaaaaggtcg cgcacttcac gaagttggtt
    18541 ttctcgccgt cggattgtgg aatgaactcg gtgtgctttc gttaatcgga tgcgggatgt
    18601 gaggagttcg cccgaaatga tcaagaagat tcccggtttt ttggctgccc tgatggcgct
    18661 cacgctcctt gccccaccgg cacaggccca tgccacacat gttctaccgg cggtcgcagc
    18721 cgaggactac tacgcagaga tcaacggagt cgagtaccgg gtgtcgcagg agcgttctca
    18781 gacctgagcg gcctgcgggg tgcaggacga caacagcaag cttgtccgta cattcactaa
    18841 aaaaggtggt ctttctggaa gtagcgctta cctcaagtgt ggatccccag gttggggcta
    18901 ccggcacatt aaggacaggc acatggatga ctggaacaac atcgccgttc ggataggcga
    18961 caactggcgg tcgttcgctg actttgcaat cgaacagatt ctcatcgcac ctgaatctgc
    19021 tacctataag tccggaaacg acacctatgc gttcacggcg cctgtgcaga tccgagacgg
    19081 tgacgggaac gtcatcagta cttatcggcc tatagtctcc gtggccaacg agtcacgcaa
    19141 catcatcact gcctaccctc ggcgcggcta ggcgctggag ggctcatgga cgacacattg
    19201 ctgttcgccg aactcgtgcg ccgactcaac ctggatgacg gcctagccga cgaggccccc
    19261 gaccggatgg gggtcctggt tcgccggtgg caaggccgtg acctggaccc tccgtacatg
    19321 ctgcatgtgg accctccgag attgggagag catctgcggt ccatggaggg catcagcgaa
    19381 ctgttcccgg acaccgcttc tgagatcggt ggactgcggc tgttcctcgt ccatatcgaa
    19441 gaagccgtcg agaccgctcc ggaaggacac cggcacctgc tgatcggccc ggccggggtg
    19501 tacgcacggc cggatgctcc accgcagacc gaccgcagcg tctaacgcag ggccgacatc
    19561 tgccgtgctg cgctattgca tcgtctcgct cgctcaggct gcggggtcgg gcatggaggt
    19621 ggtgccgaat gaggggtgtt acgcgaccac gttccactga ggacacctac gagtcggcgt
    19681 tcccggacgt ggccaaggcg gcggcggaag cgaccgcgct gttgttgcgc ggggcggcgc
    19741 ccgtgtcggg gtgtgggcgg ctgacacccc ggacggcccc cagggtaggg cgtggggtgt
    19801 tgggggcgga catggcggca cacggccgtg tccgccccca cgcggtttcg gcgcccggtg
    19861 tcgggggcgg ggcaccctgt aagggcggcg gttctcagtc cggtgggagt accttgtact
    19921 gaggtgcaac tggggagcac gtatggagca cgaacgggcc ccagacgggc ctcgcgcctc
    19981 gtctgttcga ctcgtgcgcc cagtttgacc tggggttttg tggcgcaccc ggcaggattc
    20041 gaacctgcgg ccatcggatt agaagttcgc tggttacgta ccgtggcgtg tcgctacgta
    20101 ccgtttcatg ccaccccatc cgatccgacg tgccgtcgga tgccgtgcgg tgccgcccgg
    20161 tgtcgtgtca gtacggaact gcggagcacg aacggagcac aaacgggccg gtggcggcgt
    20221 ccgatggcac ctcgcgaggt tctcgttcga cggtcgaagt gcgccggttc ggcttgccgg
    20281 gcggtggaaa cgggtctgtg cagattgccg atgacagcgc ggtgctcgag aggcggctgt
    20341 catcggggta ttcgtctgcc gatggggatg gtcagcagcc ggaagtcgcc tttgtggcct
    20401 tcgagcccgg agtaccgtga ccatgtgcac cggtacgcgc cgcgcagcgc caggggttct
    20461 tcgcgtttgt cggtggtgcc ctggccagcg taggggcgcc aggcacggac gcccgccagg
    20521 tgggcgcctt cgtagagacg gaaagcgtcg tggatggcgg gacggtcgtg gtcggggcgt
    20581 ttccagtaca gggggtcgtt ggtcaggagc aggacgccgc cgctccagcc caggtgccgg
    20641 tcggtcagct gttccaggtc gcggatgtcg cggaccacgt cgtagcaggt gagctcctgg
    20701 gcgccgtggt tcttgagggc gaagcgctca cccgccacgg tctcggtcca ggcggcccga
    20761 gggtatcgca gccgcagggc caggtgcgcg cccaacgagg ggatggacac gcgcaggtcc
    20821 acgcgttcgg ttccccggcc ttcaccgggg tggacttcca gggacgggtc gcaggcgcgg
    20881 atgctgcggg cgagggagtg caccaggtcc gacttcgagt ggaacaccgg ccgtgtacgc
    20941 ctcaggtgct cgatccacgc cccgaatcgg ctggcccagc tgctcatgcc ggtcaaccta
    21001 ccgttgcacg actacgcacg gaacaagttc cctcgaaccc ggtaaatgcc acc
//
