LOCUS       NZ_CP118233            14813 bp    DNA     circular CON 13-JUL-2024
DEFINITION  Micromonospora chalcea strain 1K05785M01 chromosome, complete
            genome.
ACCESSION   NZ_CP118233
VERSION     NZ_CP118233.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora chalcea
  ORGANISM  Micromonospora chalcea
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Study on the Growth Characteristics and Drug Resistance Related
            Proteins of Micromonospora chalcea MCCC 1K05785
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2023) Tianjin University, Tianjin University,
            Weijinlu Nub92, Tianjin, Tianjin 300072, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2022
            Assembly Method                   :: CLC NGS Cell v. 5.29
            Assembly Name                     :: TJU-micro-1.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028768405.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 23:01:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,224
            CDSs (total)                      :: 6,161
            Genes (coding)                    :: 6,110
            CDSs (with protein)               :: 6,110
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 51
            CDSs (without protein)            :: 51
            Pseudo Genes (ambiguous residues) :: 0 of 51
            Pseudo Genes (frameshifted)       :: 16 of 51
            Pseudo Genes (incomplete)         :: 40 of 51
            Pseudo Genes (internal stop)      :: 2 of 51
            Pseudo Genes (multiple problems)  :: 7 of 51
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:37:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5704941
            Orig. end                         :: 5719754
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP118233.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..14813
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NAGGN"
                     /region_number="25"
                     /rules="((TIGR03104 or cds(GATase_7 and Asn_synthase)) and
                     TIGR03103 and (TIGR03106 or Peptidase_M42))"
                     /tool="antismash"
     cand_cluster    1..14813
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /kind="single"
                     /product="NAGGN"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..14813
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:9813](-)"
                     /cutoff="10000"
                     /detection_rule="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /neighbourhood="5000"
                     /product="NAGGN"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..9813)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /neighbourhood="5000"
                     /product="NAGGN"
                     /protocluster_number="1"
     misc_feature    complement(124..138)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            complement(175..1221)
                     /db_xref="GeneID:91359648"
                     /locus_tag="PVK74_RS25845"
                     /old_locus_tag="PVK74_25845"
     CDS             complement(175..1221)
                     /codon_start=1
                     /db_xref="GeneID:91359648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787506.1"
                     /locus_tag="PVK74_RS25845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_25845"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_043326540.1"
                     /transl_table=11
                     /translation="MGDAGSVAPVHWQRVRQIARLAAIGTGATVAATAATGGVLLGQAR
                     QARRTIPMAQAPPPRCDGVYGAKLPGPPVTMVILGDSSAAGYGVHRRRETPGSLLATGL
                     SRRLHRPVRLHRFAVVGALSSGLKPQVESALEVEPDVAVILVGGNDVTNRTPPGLAVRY
                     LVDAVRTLRAAGCEVVVGTCPDLGTIRPIQPPLRWLARRWSRQLAAAQTVGVVEAGGRA
                     VSLGDMLGPRFAAEPARMFAWDRFHPSAEGYAIAAAALLPTVLSALGAVPERRPVLPGV
                     EGVRSLPEAAHEAARHAGTEVSGAQLRGRDRGPGGRWAQLRRRAFFGVGALPPTGSAAD
                     SATLEETA"
     gene            1363..1719
                     /db_xref="GeneID:91359649"
                     /locus_tag="PVK74_RS25850"
                     /old_locus_tag="PVK74_25850"
     CDS             1363..1719
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007074683.1"
                     /locus_tag="PVK74_RS25850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_25850"
                     /product="YkvA family protein"
                     /protein_id="WP_013474058.1"
                     /transl_table=11
                     /translation="MGKTLKRSAAFAALARALAAGTRGGPSLGARLAALPRMIRATTRG
                     EYDGGLRLALMAGATAYIVSPIDLLPEIPLAIFGLADDAVMVTWLAGSVLAETERFLEW
                     EARRSSVIPGHVVP"
     gene            1796..3166
                     /db_xref="GeneID:91359650"
                     /locus_tag="PVK74_RS25855"
                     /old_locus_tag="PVK74_25855"
     CDS             1796..3166
                     /EC_number="4.2.1.22"
                     /GO_function="GO:0004122 - cystathionine beta-synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019344 - cysteine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359650"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018742048.1"
                     /locus_tag="PVK74_RS25855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_25855"
                     /product="cystathionine beta-synthase"
                     /protein_id="WP_210873750.1"
                     /sec_met_domain="PALP (E-value: 2.4e-72, bitscore: 242.3,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYYDNVVELIGNTPLVRLRNVTEGIQATVLAKVEYVNPGGSVKD
                     RIAMRMVEDAEKAGILRPGGTIVEPTSGNTGVGLALVAQLKGYRCVFVCPDKVSQDKQD
                     VLRAYGAEVVVCPTAVAPEDPRSYYNVSDRLAREIPGAWKPNQYSNPANPRSHYETTGP
                     ELWKQTEGKITHFVAGVGTGGTISGIGRYLKEASEGRVKVIGADPEGSVYSGGTGRPYL
                     VEGVGEDFWPETYDRKIADEIVEVSDKESFEMTRRLAREEGLLVGGSCGMAVVGALEVA
                     RKAGPDDVIVVLLPDGGRGYLSKIFNDKWMARYGFLDDSGTEPTVADALAGKPGGLPEL
                     VHVHPTETVRDAIDYMREYGVSQLPVLKAEPPVVTGEVAGSIAEKDLLDALFTGQAHLH
                     DTIERHMGEPLPMIGGGQPVSEAVGLLEKADAALVLVDGKPKGVLTRQDLLAHLGAR"
     gene            complement(3256..3765)
                     /db_xref="GeneID:91359651"
                     /locus_tag="PVK74_RS25860"
                     /old_locus_tag="PVK74_25860"
     CDS             complement(3256..3765)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787509.1"
                     /locus_tag="PVK74_RS25860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_25860"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_210884227.1"
                     /transl_table=11
                     /translation="MTISLRSATEADLMAVGALHQRSRVAAYSSFLPPEALADPTPEAM
                     GRYWVERLTWEGADHRMTVAERDGKLVGFSYLGPDDEGDPATGLLNAIHLEPTERGRGT
                     GRALMVDALDAMRARGWTRAVLWVLRDNAHARRFYERGGWTATGDERDEHIGRVLVPQL
                     RYARRL"
     gene            complement(3762..4691)
                     /db_xref="GeneID:91359652"
                     /locus_tag="PVK74_RS25865"
                     /old_locus_tag="PVK74_25865"
     CDS             complement(3762..4691)
                     /EC_number="3.1.26.11"
                     /codon_start=1
                     /db_xref="GeneID:91359652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018586560.1"
                     /locus_tag="PVK74_RS25865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_25865"
                     /product="ribonuclease Z"
                     /protein_id="WP_274477422.1"
                     /transl_table=11
                     /translation="MSMRELVVLGTASQAPTRQRNHNGYLLRWDDEVILFDPGEGSQRQ
                     MLHTGVTATDLTRICVTHFHGDHCLGLPGMIQRLSLDRVPRPVAVHFPAGGAEYFARLR
                     HASSFYETAELAVEPIDADGQRITLGIGTLEARRLRHPIETYGYRLVEPDGCRMLPERL
                     AAYGIAGPDTGRLLRDGHLDRDGRRVTRDEVSVTRPGQRFAFVMDTGLCDGVYALAEHA
                     DLLVIESTFLESEAALAAEVGHLTAGQAARVAAESGVRTLVLTHFSQRYADPRRFHDEA
                     REHFSGDLVIAEDLQTVQVPPRRVPSPG"
     misc_feature    4914..4929
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.95"
                     /tool="antismash"
     gene            complement(5001..6185)
                     /db_xref="GeneID:91359653"
                     /locus_tag="PVK74_RS25870"
                     /old_locus_tag="PVK74_25870"
     CDS             complement(5001..6185)
                     /codon_start=1
                     /db_xref="GeneID:91359653"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     Peptidase_M42"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03106"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787511.1"
                     /locus_tag="PVK74_RS25870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_25870"
                     /product="osmoprotectant NAGGN system M42 family peptidase"
                     /protein_id="WP_104114273.1"
                     /sec_met_domain="TIGR03106 (E-value: 1.9e-146, bitscore:
                     485.8, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M42 (E-value: 2.1e-56, bitscore:
                     189.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTARKPQPLKLDLDYLRQVLVELLEIPSPSGRTDHIQQYVGERLS
                     AIGISSTLTRRGALSACLPGPRETGADRAIVVHTDTIGGMVKRLKENGRLEVNPIGTHS
                     ARFAEGAHVRIFTDDLERVVTGQVLPLKASGHRYNEAVDLQGVGWELVEVRVDEPVHDE
                     AGLRALGIDAGDFVAFLPNPTITPNGYVKSRHLDDKAGVAAVLTAFKAMVDAGVTPAVT
                     AHLLVTVTEEIGHGASHGLDPDVAEIVSVDAAVVAPGQQSRETAATLAMGDGVGPFDYH
                     LTRNLASIAKEHGVDLVRDVFDYYRSDVAAAVEAGAHARVALLGFGVDATHGHERTHLD
                     GLHQLTQLLCLYLQSPLVFPEWDAEPEGDLADFPSLAVQPANEDGPREGPIGLD"
     gene            complement(6182..8020)
                     /db_xref="GeneID:91359654"
                     /gene="ngg"
                     /locus_tag="PVK74_RS25875"
                     /old_locus_tag="PVK74_25875"
     CDS             complement(6182..8020)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359654"
                     /gene="ngg"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03103"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787512.1"
                     /locus_tag="PVK74_RS25875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_25875"
                     /product="N-acetylglutaminylglutamine synthetase"
                     /protein_id="WP_274477423.1"
                     /sec_met_domain="TIGR03103 (E-value: 1.3e-238, bitscore:
                     791.4, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 2.3e-07, bitscore: 29.1,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 5.6e-07,
                     bitscore: 27.7, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTLATGTARTDRERVLGRRRERIGPGGDPVAPGTPEQRQPEPT
                     STDASGVVLDCGWGRLVFGQTFDDQVHVADVLRSEAVGARDICIYLRDPHVLVSRLPDE
                     LFIDPSLTYRLPLGEKRPAATEGGEVPGLTVRPLRDAVDAEAVNRIYARNGMVTAPVEI
                     LVDNAGTDRFLHLVAEDTTGEVVGTITGVDHVAVFGDPENGASLWCLTVDFNTAPPGTG
                     QALLTALADRLDGRGRAFVDLSVLAENSGAIRLYERLGFHRTGTLCVKRKNPINERLFL
                     PAMPEGYDELNPYAKIVADEAMRRGIRVEVTDPHWGELKLTTGGRTIHTRESLSELTSA
                     VAMSRCDDKRVTRRILTEAGLSVPRGRTATGEPDDVAFLNDVGPVVVKPARGEQGNGIT
                     VGVRTPEALTAAVELARRFCPDVLIEELRAGEDLRVVVIDHEVVAAAVRRPAQITGDGV
                     HDITELIERQSRRRAAATGGESRIPIDDMTREVVAEAGYRMHDVLPEGEVLAVRRTANL
                     HTGGTIHDVTAELHPAIAEACVTASRALDIPVTGLDLLVPAPDRPEHVFIEANERPGLA
                     NHEPQPTAERFVDLLFPGTRAPQRLWSPAGAASSGA"
     gene            complement(8023..9813)
                     /db_xref="GeneID:91359655"
                     /locus_tag="PVK74_RS25880"
                     /old_locus_tag="PVK74_25880"
     CDS             complement(8023..9813)
                     /codon_start=1
                     /db_xref="GeneID:91359655"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     GATase_7"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     Asn_synthase"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03104"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007074689.1"
                     /locus_tag="PVK74_RS25880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_25880"
                     /product="N-acetylglutaminylglutamine amidotransferase"
                     /protein_id="WP_274477424.1"
                     /sec_met_domain="TIGR03104 (E-value: 2.5e-284, bitscore:
                     942.4, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 1.3e-39, bitscore:
                     133.4, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.1e-86, bitscore:
                     290.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGLAGEFRRDGSRADVSAVERMAATMSDRGPDDSGVWSQGPTAL
                     GHRRLKIIDLSAASGQPIVDAAAGLTGVFNGCIYNYRELRAELQAKGHLFFSSGDSEVV
                     VKAYAEWGLDFVDHLIGMFAVAISERDTGRLVLARDRLGIKPLYLAESPGVVRFASTLP
                     ALLAGGGIDTTIDRVALAHYLSFHSIVPPPRTILAGVTKLPPATVRVYEADGSTHERVY
                     WDPAFGRAAERAGWSERDWQDALLDSLTTAVRRRMVADVPVGVLLSGGLDSSLVVALLA
                     GEGQARSGLATFSIGFDAVGGREGDEFVYSDLVAKTFGTDHHQIRVPTGDLLPPLEAAV
                     SAMSEPMVSHDCVAFWLLSQEVAKHVKVVQSGQGADEILGGYHWYPPLAGVDREQALET
                     YAKAFFDRDAAGLARVLNPAWLADGDPAREFVAAHLGRPGAQTAVDAGLRIDTQVMLTD
                     DPVKRVDNMTMAHGLEARVPFLDHEFVELAASCPPELKLAQGGKGVLKEIGRRVLPHEV
                     IDRPKGYFPVPGLTHLEGKLLDRVRDALTAPEARRRDLFRADYVDALLADPNAELTPLN
                     GNKLWQLGLLEMWLQSHGID"
     misc_feature    complement(9844..9858)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.52"
                     /tool="antismash"
     misc_feature    9894..9907
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.55"
                     /tool="antismash"
     misc_feature    complement(9895..9908)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.99"
                     /tool="antismash"
     misc_feature    9949..9965
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.29"
                     /tool="antismash"
     misc_feature    complement(9987..10000)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.21"
                     /tool="antismash"
     gene            complement(10098..10760)
                     /db_xref="GeneID:91359656"
                     /gene="msrA"
                     /locus_tag="PVK74_RS25885"
                     /old_locus_tag="PVK74_25885"
     CDS             complement(10098..10760)
                     /EC_number="1.8.4.11"
                     /GO_function="GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA]"
                     /GO_function="GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /GO_process="GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359656"
                     /gene="msrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020215983.1"
                     /locus_tag="PVK74_RS25885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_25885"
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="WP_274477425.1"
                     /transl_table=11
                     /translation="MFLRRMKAEMISPDQALPGRPIAMPIADRHEVLPSTLKGPFPEGA
                     QVAVFGMGCFWGAERLFWTLPGVITTSAGYAGGYTTNPTYEEVCSGMTGHAEVVQVVYD
                     PSKIAYEDLLKVFWENHDPTQGMRQGNDVGTQYRSAIYTITDEQAAAAKASRDAFAPIV
                     ARAGKGEITTEIAPLGDYYFAEDYHQQYLAPTKNPNGYCNHGPNGLSCPVGVARTAG"
     gene            complement(10837..11250)
                     /db_xref="GeneID:91359657"
                     /locus_tag="PVK74_RS25890"
                     /old_locus_tag="PVK74_25890"
     CDS             complement(10837..11250)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013474065.1"
                     /locus_tag="PVK74_RS25890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_25890"
                     /product="HIT family protein"
                     /protein_id="WP_043326522.1"
                     /transl_table=11
                     /translation="MSGCVFCGIVAGEVPAFRVTDEPDGVAFLDTRPVFKGHVLVVPRT
                     HLVALSDLPPDALPGYFRLVQRIAVAVETGLDAGGTFVAMNNRVSQSVPHLHTHVVPRT
                     KGDGLRGFFWPRTRYAGDAEAEAFAGRISAALA"
     gene            complement(11375..12067)
                     /db_xref="GeneID:91359658"
                     /locus_tag="PVK74_RS25895"
                     /old_locus_tag="PVK74_25895"
     CDS             complement(11375..12067)
                     /codon_start=1
                     /db_xref="GeneID:91359658"
                     /inference="COORDINATES: protein motif:HMM:NF020419.4"
                     /locus_tag="PVK74_RS25895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_25895"
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="WP_274477426.1"
                     /transl_table=11
                     /translation="MDELHTRLLHVGFRAGDDLGLVLAGGYALAAHDLVSRPSRDIDFA
                     TATALPLPLVAARLAEAYRAGEFGCRVVEATPRMARLLVEGQGFACEVDLLKEAIGPPA
                     RLQIGPVLALEDAIGLKVRALHDRAAHRDYIDVCAASRIVEFAGLESLGAQHTVAFSLH
                     ELADRLGGVDELDVETFASYGLGEDEIGGLRRWARRWEADIRARLANGETGPTGIPDDD
                     WDAYLDRA"
     gene            complement(12070..12396)
                     /db_xref="GeneID:91359659"
                     /locus_tag="PVK74_RS25900"
                     /old_locus_tag="PVK74_25900"
     CDS             complement(12070..12396)
                     /codon_start=1
                     /db_xref="GeneID:91359659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787517.1"
                     /locus_tag="PVK74_RS25900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_25900"
                     /product="hypothetical protein"
                     /protein_id="WP_064447694.1"
                     /transl_table=11
                     /translation="MSTTEALPSRLHGVADRIPTSLDDLKGPERGRVTLPTRLAWSGLS
                     EFDVDDSGQRLTLYRTLMDCGQREDIVRYVNPALLRQDWSRIRKLTAHRVIRLWESRMP
                     GLAA"
     gene            12497..13639
                     /db_xref="GeneID:91359660"
                     /locus_tag="PVK74_RS25905"
                     /old_locus_tag="PVK74_25905"
     CDS             12497..13639
                     /EC_number="2.5.1.48"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /NRPS_PKS="Domain: Beta_elim_lyase (47-177). E-value:
                     1.1e-08. Score: 26.7. Matches aSDomain:
                     nrpspksdomains_PVK74_RS25905_Beta_elim_lyase.1"
                     /codon_start=1
                     /db_xref="GeneID:91359660"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011904831.1"
                     /locus_tag="PVK74_RS25905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_25905"
                     /product="cystathionine gamma-synthase"
                     /protein_id="WP_274477427.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.2e-06, bitscore:
                     26.4, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.1e-07,
                     bitscore: 29.9, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 1.9e-05, bitscore:
                     22.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRHGFDTLAIHAGQAPEARTGAVIPPIYQTSTYAQDAVGAPREGY
                     EYSRSGNPTRDALQECLAALEGGQVGLAFASGLAAEDTLLRTVCKPGDHVVIPDDAYGG
                     TYRLFAKVAERWGLDYTPAKVSDPDAVRAAIRPGATRIVWVETPTNPLLGIADIAALAA
                     VAHDAGALLVVDNTFASPYLQQPIAFGADVVVHSTTKYVGGHSDVVGGALVAADRALGE
                     ELRYHQNAMGAINGPFDAWLTLRGIKTLGVRMDRHCDNAERIAAYLDGHAQVAQVIYPG
                     LPSHPGHEVAAKQMRRFGGMISFRAAGGEEHAVDICNRSRLFVLAESLGGVESLIEHPG
                     RMTHASAAGSPLEVPGDLVRLSVGIETVDDLLADLEQALG"
     aSDomain        12638..13027
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PVK74_RS25905_Beta_elim_lyase.1"
                     /evalue="1.10E-08"
                     /label="PVK74_RS25905_Beta_elim_lyase.1"
                     /locus_tag="PVK74_RS25905"
                     /protein_end="177"
                     /protein_start="47"
                     /score="26.7"
                     /tool="antismash"
                     /translation="SRSGNPTRDALQECLAALEGGQVGLAFASGLAAEDTLLRTVCKPG
                     DHVVIPDDAYGGTYRLFAKVAERWGLDYTPAKVSDPDAVRAAIRPGATRIVWVETPTNP
                     LLGIADIAALAAVAHDAGALLVVDNT"
ORIGIN
        1 gcccaccgtg ccggccagca gcgacagggc cgccgcccgg ccccaccggg ccacctcgtt
       61 ccgctcgctc atgacagcac tccgcttcgc tccgtgccgt catgaggcac gtttgcgctg
      121 agctggccga ttcgctcgct gcgctcgctc atgacagcac tccgcttcgc tcgctcatgc
      181 cgtttcctcc agggtggccg agtcggcggc gctgccggtc gggggcagcg cgccgacgcc
      241 gaagaaggcc cgtcggcgaa gctgcgccca gcgtccgccg ggcccgcggt cgcgaccccg
      301 gagctgggcg ccgctgacct ccgtgccggc gtgccgggcc gcctcgtgag ccgcctccgg
      361 gagcgaccgt acgccttcca cgccgggcag gacaggcctg cgttccggga ccgcgcccag
      421 cgcggacagc acggtgggca gcaacgccgc cgcggctatc gcgtacccct ctgcggaggg
      481 gtggaaccgg tcccaggcga acatccgggc gggctcggcg gcgaaccgcg gcccgagcat
      541 gtcgccgagt gagacggccc ggccgccggc ctcgaccacg cccaccgtct gcgcggccgc
      601 gagctggcgg ctccagcgcc gggccagcca gcgcagcggc ggctggatcg gccggatggt
      661 gcccaggtcg ggacaggtgc cgacgaccac ctcgcagccg gccgcccgca gcgtgcggac
      721 cgcgtccacc aggtagcgca cggccagccc cggcggggtg cggttggtga cgtcgttgcc
      781 gcccaccagg atcaccgcca cgtccggctc gacctccagg gcggactcga cctgcggttt
      841 cagcccggac gagagcgcgc ccaccacggc gaaccggtgc aggcgtaccg gccggtgcag
      901 gcggcgggac agcccggtgg ccagcagcga gcccggtgtc tcccggcgcc tgtgcacgcc
      961 gtagccggct gctgaggagt cgcccaggat gaccatggtg accggcgggc cgggcagctt
     1021 cgcgccgtac acgccgtcgc agcgcggtgg cggggcctgc gccatcggga tggtgcgccg
     1081 ggcctgccgg gcctggccga gcagcacccc gccggtggcg gcggtggccg ccaccgtggc
     1141 gcccgtgccg atcgccgcga ggcgggcgat ctgccggacg cgctgccagt ggaccggcgc
     1201 gacggaacca gcgtccccca tgaaccgaca gtatcgcgcc ggtacgacca ctgctgtcct
     1261 tgatcggatg gctgggcggc gcccggactg ggtaccgatg ggggtggcgg acgcgggctt
     1321 gcccccgggc cgcaccatgg tcgggcggag aggggcgaag acatggggaa gacgttgaag
     1381 cgcagcgccg cgttcgccgc gctggcccgg gcgctggcgg ccggtacgcg gggcgggccg
     1441 tcgctcgggg cccggctggc ggcgctgccg aggatgatcc gcgccaccac caggggcgag
     1501 tacgacggcg gcctgcgcct ggcgctgatg gccggcgcga ccgcgtacat cgtcagcccg
     1561 atcgacctgc tgccggagat cccgctggcg atcttcgggc tggccgacga cgcggtgatg
     1621 gtcacctggc tggccggcag cgtgctcgcc gagaccgaac ggttcctgga gtgggaggca
     1681 cgtcgcagct cggtcatccc ggggcatgtg gtgccctgac ggcacgtacg ctggtcggcg
     1741 aactgacggc tgaccgaccg ccccacgacg gcggcgcgac gaagggcaca acgaggtgca
     1801 gtactacgac aacgtcgtcg agctgatcgg caacaccccg ctggtccgcc tgcgcaacgt
     1861 caccgagggc atccaggcca ccgtgctggc gaaggtggag tacgtcaacc cgggcggctc
     1921 ggtcaaggac cggatcgcga tgcgcatggt ggaggacgcc gagaaggcgg gcatcctgcg
     1981 gccgggcggc acgatcgtgg agccgaccag cggcaacacc ggcgtcgggc tggccctggt
     2041 ggcccagctc aagggctacc gctgcgtctt cgtctgcccg gacaaggtca gccaggacaa
     2101 gcaggacgtg ctgcgcgcgt acggcgccga ggtggtggtc tgcccgaccg ccgtcgcgcc
     2161 ggaggacccg cgctcctatt acaacgtgtc cgaccggctg gcccgggaga tccccggcgc
     2221 gtggaagccc aaccagtaca gcaacccggc caacccgcgc tcgcactacg agaccaccgg
     2281 cccggagctg tggaagcaga ccgaaggcaa gatcacccac ttcgtggcgg gcgtcggcac
     2341 cggcggcacc atctccggca tcggccgcta cctcaaggag gcgtccgagg gccgggtcaa
     2401 ggtgatcggc gcggacccgg agggctcggt ctactcgggc ggcaccggcc ggccgtacct
     2461 ggtcgagggc gtcggtgagg acttctggcc ggagacgtac gaccggaaga tcgccgacga
     2521 gatcgtcgag gtgtcggaca aggagtcctt cgagatgacc cgccggctcg cccgcgagga
     2581 gggtctgctg gtcggcggct cctgcggcat ggcggtggtg ggcgcgctgg aggtggcccg
     2641 caaggccggc ccggacgacg tgatcgtggt gctgctgccg gacggcggcc ggggctacct
     2701 gtcgaagatc ttcaacgaca agtggatggc ccggtacggc ttcctggacg actcgggcac
     2761 cgagccgacg gtcgccgacg cgctcgccgg caagcccggt ggcttgcccg agctggtgca
     2821 cgtgcacccg accgagacgg tccgcgacgc gatcgactac atgcgcgagt acggcgtctc
     2881 gcagctcccg gtactcaagg ccgagccgcc ggtggtgacc ggtgaggtgg ccggttcgat
     2941 cgccgagaag gacctgctcg acgcgctgtt caccggccag gcccacctgc acgacacgat
     3001 cgagcggcac atgggcgagc cgctgccgat gatcggcggc ggccagccgg tgagcgaggc
     3061 ggtcgggctg ctggagaagg cggacgcggc gctggtgctg gtcgacggca agcccaaggg
     3121 cgtgctgacc cgccaggacc tgctggccca cctcggcgcc cgctgaccct gcttgtaagg
     3181 aaggggcccc ttttaacacc gcggtgttaa aaggggcccc ttcctctacc ggaggcgtta
     3241 ataaggggcc cttccttaca agcggcgggc gtagcggagt tgggggacca gcacccggcc
     3301 gatgtgttcg tcccgctcat caccggtggc ggtccagccg ccgcgctcgt agaaacggcg
     3361 cgcgtgggcg ttgtcccgca gcacccacag caccgcgcgc gtccagcccc gggcccgcat
     3421 cgcgtcgagc gcgtccacca tcagcgcccg tccggtgccc cggccccgct cggtcggctc
     3481 caggtggatc gcgttgagca gcccggtcgc cgggtcgccc tcgtcgtcgg gcccgaggta
     3541 gctgaagccc accagcttcc cgtcccgctc ggccaccgtc atccggtggt ccgcgccctc
     3601 ccaggtcagc cgttccaccc agtagcggcc catcgcctcc ggcgtcgggt cggccagcgc
     3661 ctcgggcggc aggaacgacg agtacgccgc cacccgggaa cgctggtgca gggcgccgac
     3721 cgccatcagg tcggcctcgg tcgcggaacg tagggagatc gtcacccggg cgacggtacc
     3781 cgccggggcg gcacctgtac cgtctgaaga tcctcggcga tcaccagatc accggagaag
     3841 tgctcgcggg cctcgtcgtg gaagcggcgc gggtcggcgt accgctgaga gaagtgggtg
     3901 agcacgagcg tgcgtacccc cgactcggcc gcgacccgcg cggcctggcc ggcggtgagg
     3961 tgcccgacct cggcggcgag cgccgcctcc gactccagga acgtcgactc gatcacgagc
     4021 aggtcggcgt gctcggcgag cgcgtacacg ccgtcgcaga gcccggtgtc catcacgaac
     4081 gcgaaccgct gccccggccg ggtcacgctc acctcgtccc gggtgacgcg gcgcccgtcg
     4141 cggtccaggt ggccgtcgcg cagcagcctt ccggtgtccg gaccggcgat gccgtacgcg
     4201 gccagccgct ccggaagcat ccggcagccg tccggctcga ccagccggta tccgtacgtc
     4261 tcgatcgggt gccgcagccg gcgggcctcc agcgtgccga tgcccagggt gatccgctgc
     4321 ccgtcggcgt cgatcggctc gactgccagt tcggcggtct cgtagaagct ggaggcgtgc
     4381 cgcagccggg cgaagtactc ggcgccgccg gccgggaagt gcaccgccac cgggcgcggt
     4441 acgcggtcca gcgagagccg ctggatcatg ccgggcagcc cgaggcagtg gtcgccgtgg
     4501 aagtgggtga cgcagatccg ggtcaggtcg gtggcggtga ccccggtgtg cagcatctgc
     4561 cgctggctgc cctcgcccgg gtcgaagagg atcacctcgt cgtcccagcg cagcaggtag
     4621 ccgttgtggt tgcgctgccg ggtcggggcc tggctggccg taccgagcac caccagctca
     4681 cgcatggaca ccgcaccctc ccgagcgcaa aaagcgaccc ccggggcttc cgcgctcgcg
     4741 cgcgggccgg ctggactggg ccgacacccc gggggtcggg tggctgtcgt ggtttcgccg
     4801 caccgctgcc acacggtctc gacgatcctg caggtgcccg cctcgcggcg ggcgagattt
     4861 cactgtcgag gacagcggct agcggacagc cacctcacga gtccgattgc tatacaagtc
     4921 tggaccacct cctttcccgt gtaccgccac gctatccact tcgcggcggc cgcggcaacg
     4981 gatttcgatc acaggcccgg tcagtccagg ccgatcgggc cctcgcgcgg gccgtcctcg
     5041 ttcgccggct gcacggcgag cgacgggaag tcggccaggt cgccctccgg ctcggcgtcc
     5101 cactcgggga acaccagcgg gctctgcagg tagaggcaga gcagctgggt gagctggtgc
     5161 aggccgtcga ggtgggtgcg ctcgtggccg tgggtggcgt ccacgccgaa cccgagcagc
     5221 gccacccggg cgtgcgcccc ggcctcgacc gcggcggcca cgtccgagcg gtagtagtcg
     5281 aacacgtccc ggaccaggtc gacgccgtgt tccttggcga tcgaggcgag gttgcgggtc
     5341 aggtggtagt cgaacgggcc gaccccgtcg cccatggcga gcgtcgccgc ggtctcccgg
     5401 gactgctggc ccggcgcgac caccgccgcg tccaccgaca cgatctccgc gacgtccggg
     5461 tccagcccgt ggctcgcgcc gtggccgatc tcctcggtga cggtgaccag caggtgcgcg
     5521 gtgaccgccg gggtgacacc ggcgtcgacc atcgccttga acgcggtcag caccgccgcc
     5581 acgcccgcct tgtcgtccag gtggcgggac ttgacgtacc cgttcggggt gatggtgggg
     5641 ttgggcagga acgcgacgaa gtccccggcg tcgatgccga gcgcccgcag cccggcctcg
     5701 tcgtgcaccg gctcgtccac ccgcacctcg accagttccc agccgacgcc ctgcaggtcg
     5761 accgcctcgt tgtagcggtg cccgctcgcc ttcagcggca gcacctggcc ggtgacgacc
     5821 cgctccaggt cgtcggtgaa gatccgcacg tgggcgccct cggcgaagcg ggcgctgtgc
     5881 gtgccgatcg ggttgacctc cagccggccg ttctccttga gccgcttcac catgccgccg
     5941 atggtgtcgg tgtgcaccac gatcgcccgg tcggcgccgg tctcccgggg accgggcaga
     6001 caggcgctca gcgccccgcg acgggtcagc gtggagctga tcccgatcgc ggagagcctc
     6061 tcgcccacgt actgctggat gtggtcggtg cgccccgacg ggctggggat ctccagcagc
     6121 tccaccagca cctggcggag gtagtcgagg tcgagcttga gcggttgggg cttgcgtgcg
     6181 gtcatgcccc agagcttgcc gcaccggccg gcgaccagag tcgctgcggt gcccgggtac
     6241 ccgggaagag caggtcgacg aagcgctcgg cggtgggctg cggttcgtgg ttggccagtc
     6301 cgggccgctc gttcgcctcg atgaacacgt gttccggccg gtccggggcg gggaccagca
     6361 ggtccagccc ggtgaccggg atgtccagcg cccggctcgc ggtcacgcac gcctcggcga
     6421 tcgccgggtg cagctcggcg gtcacgtcgt ggatcgtgcc gccggtgtgc aggttggccg
     6481 tccggcgtac cgcgagcacc tcgccctccg ggagcacgtc gtgcatccgg tacccggcct
     6541 cggccaccac ctcgcgggtc atgtcgtcga tcgggatgcg ggactcgccc ccggtggcgg
     6601 cggcccggcg gcggctctgc cgctcgatca gctcggtgat gtcgtgcacc ccgtcgccgg
     6661 tgatctgcgc cgggcggcgt accgcggcgg cgaccacctc gtggtcgatc accacgaccc
     6721 gcaggtcctc gcccgcgcgc agctcctcga tcagtacgtc cgggcagaac cggcgggcca
     6781 gctcgacggc cgcggtcagc gcctcgggcg tacgcacgcc gacggtgatg ccgttgccct
     6841 gctcgccccg cgccggcttg accaccaccg gacccacgtc gttcaggaac gccacgtcgt
     6901 cgggctcacc ggtggcggta cgcccgcgcg gcaccgacag gcccgcctcg gtgaggatgc
     6961 gccgggtcac ccgcttgtcg tcgcagcggc tcatcgccac cgccgaggtc agctccgaca
     7021 gcgactcgcg ggtgtggatg gtccggccgc cggtggtcag cttcagctca ccccagtgcg
     7081 ggtcggtcac ctccacccgg atgccgcggc gcatcgcctc gtccgcgacg atcttcgcgt
     7141 acgggttcag ctcgtcgtac ccctcgggca tggcgggcag gaacaggcgc tcgttgatcg
     7201 ggttcttccg cttcacgcag agcgtgccgg tgcggtggaa gccgaggcgc tcgtacagcc
     7261 ggatcgcgcc cgagttctcg gccagcacgg acaggtccac gaacgcccgg ccgcgcccgt
     7321 cgagccggtc ggcgagcgcg gtgagcagcg cctgcccggt gccgggcggg gcggtgttga
     7381 agtccacggt caggcaccac aggctggcgc cgttctccgg gtcaccgaag accgcgacgt
     7441 ggtccacgcc ggtgatggtg ccgaccacct cacccgtggt gtcctcggcc accaggtgca
     7501 ggaaccggtc cgtgccggcg ttgtccacga ggatctcgac cggggcggtg accatgccgt
     7561 tgcgcgcgta gatccggttc accgcctccg cgtcgacggc gtcacgcagc ggccggacgg
     7621 tcagcccggg cacctcgccg ccctcggtcg cggcgggccg cttctcgccc agcggcagcc
     7681 ggtacgtcag cgacgggtcg atgaacagct cgtccggcag ccgcgacacc agcacgtgcg
     7741 ggtcgcgcag gtagatgcag atgtcccggg cgccgaccgc ctcggagcgc agcacgtcgg
     7801 ccacgtgcac ctggtcgtcg aacgtctgcc cgaacaccag ccggccccag ccgcagtcca
     7861 gcaccacgcc cgaggcgtcg gtggacgtgg gctccggctg ccgctgctcc ggcgtacccg
     7921 gtgcgaccgg gtcaccgccg gggccgatgc gttcccggcg gcgccccagc acccgttccc
     7981 ggtcggtacg tgccgttccg gtggcgaggg tgtcggtcac ggtcagtcga ttccgtggct
     8041 ctggagccac atttccagga gtcccagttg ccacagcttg tttccgttca acggggtcag
     8101 ttcggcgttc gggtcggcga gcagcgcgtc gacgtagtcg gcgcggaaca ggtcgcgacg
     8161 gcgcgcctcg ggcgcggtga gcgcgtcgcg tacccggtcg aggagcttgc cctccaggtg
     8221 ggtgagtccg ggcaccggga agtagccctt gggccggtcg atgacctcgt ggggcaggac
     8281 ccgccggccg atctccttga gcacgccctt gccgccctgg gccagcttca gctccggcgg
     8341 gcagctcgcg gccagctcga cgaactcgtg gtcgaggaac ggcacccggg cctccagccc
     8401 gtgcgccatg gtcatgttgt cgacccgctt caccgggtcg tcggtcagca tgacctgggt
     8461 gtcgatccgc aggccggcgt cgacggcggt ctgcgcgccc gggcggccca ggtgcgcggc
     8521 gacgaactcc cgcgccgggt cgccgtcggc cagccacgcc gggttgagca cccgggccag
     8581 tccggccgcg tcgcggtcga agaacgcctt cgcgtacgtc tcgagcgcct gctcccggtc
     8641 caccccggcg agcggcgggt accagtggta gccgcccagg atctcgtccg cgccctgacc
     8701 cgactgcacc accttgacgt gcttcgcgac ctcctggctg agcagccaga acgcgacgca
     8761 gtcgtggctg accatcggtt cgctcatggc cgagacggcg gcctccagcg gcggcagcag
     8821 gtcaccggtg ggcacccgga tctggtggtg gtcggtgccg aacgtcttcg cgaccaggtc
     8881 ggagtagacg aactcgtcgc cctcccggcc gcccaccgcg tcgaagccga tggagaacgt
     8941 ggccaggccg gaccgggcct gcccctcgcc ggcgagcagc gcgaccacca ggctggagtc
     9001 gaggccgccg gagagcagca cgcccaccgg aacgtcggcc accatgcggc ggcgtacggc
     9061 ggtggtcagc gagtcgagca gcgcgtcctg ccagtcccgc tcggaccagc cggcccgctc
     9121 ggcggcgcgg ccgaacgccg ggtcccagta gacccgctcg tgggtggagc cgtccgcctc
     9181 gtacacccgg accgtggccg gcggcagctt ggtgacgccg gcgaggatgg tgcgcggcgg
     9241 cggcacgatg ctgtggaagc tcaggtagtg ggcgagcgcc acccggtcga tggtggtgtc
     9301 gatgccgcca ccggcgagca gcgccggcag ggtcgaggcg aaccggacca cgccggggct
     9361 ctcggccagg tagagcggct tgatgccgag gcggtcccgg gccagcacca ggcggccggt
     9421 gtcgcgctcg ctgatcgcca ccgcgaacat gccgatcagg tggtcgacga agtcgagccc
     9481 ccactcggcg tacgccttga ccactacctc gctgtcgccg gacgagaaga acaggtggcc
     9541 cttggcctgc agttcggcgc gtagttcccg gtagttgtag atgcagccgt tgaagacacc
     9601 ggtgagcccg gcggcggcgt ccacgatggg ttggccgctc gccgcggaca ggtcgatgat
     9661 cttcaggcgc cggtgtccca gcgcggtcgg cccttgcgac cagacgccgc tgtcgtcggg
     9721 ccctcggtca ctcatcgtgg ccgccatccg ctccacggcc gagacatcgg cgcgtgaacc
     9781 gtcacggcgg aactctcccg caagtccgca catacgagcc aatgctgcca gaggttgttt
     9841 cggttcgcct gttgagacga tgacgaacgt gtgacagctt gctacgatgc gccgtcacgc
     9901 agcgtggttg ccgcgcacag cgtcgcttcc tgccccccag ggcgcggatg ccggaaaatc
     9961 gggcccgtgc cggctgtgag gaacgccgca tgcccgtcca gccgcagccg gaatccgcga
    10021 tcttggagtt gtggtgcctg tgatgccggt ttcgcgaggg ttgccaggca ccacaactcc
    10081 aagatcggtg gaggggtcta gccggcggtg cgggccacgc cgaccgggca gctcagcccg
    10141 ttcggtccgt ggttgcagta gccgttcggg ttcttcgtcg gcgccaggta ctgctggtgg
    10201 tagtcctcgg cgaagtagta gtcgccgagc ggcgcgatct cggtggtgat ctcacccttg
    10261 ccggcccggg ccacgatcgg cgcgaacgcg tcccgcgacg ccttcgcagc ggcggcctgc
    10321 tcgtcggtaa tggtgtagat cgccgagcgg tactgggtgc ccacgtcgtt gccctggcgc
    10381 atgccctggg tcgggtcgtg gttctcccag aagaccttga gcaggtcctc gtaggcgatc
    10441 ttcgacgggt cgtagaccac ctggaccacc tcggcgtgcc cggtcatacc cgagcacacc
    10501 tcctcgtacg tcgggttggt ggtgtagcca cccgcgtagc cggcggacgt ggtgatcacg
    10561 ccggggaggg tccagaacag ccgctcggcg ccccagaagc agcccatgcc gaagacagcg
    10621 acctgcgcgc cctcggggaa cgggcccttc agcgtcgacg gcagcacctc gtgccggtcg
    10681 gcgatcggca tcgcgatcgg gcggcccggc agggcctggt caggagagat catctcggcc
    10741 ttcatgcggc ggaggaacac ggtgggactc ctctcttggc tttcccagcg tgtgcaacag
    10801 cgtggccccc cggttcctta cccgcccacc gcgacgtcag gccagcgccg ccgagatccg
    10861 cccggcgaac gcctcggcct cggcgtcacc tgcgtaccgg gtacgcggcc agaagaagcc
    10921 gcgcagaccg tcgcccttcg tcctgggaac cacgtgggtg tgcaggtgcg gtacggactg
    10981 ggacacccgg ttgttcatcg ccacgaacgt cccaccggcg tcgagaccgg tctccaccgc
    11041 cacggcgatg cgctggacca gccggaagta gccgggcagt gcgtcgggcg gcaggtcgga
    11101 cagggcgacc aggtgggtgc ggggcaccac gagcacgtgc cccttgaaca ccgggcgggt
    11161 gtccaggaac gcgaccccgt ccggctcgtc ggtgacccgg aacgcgggca cctcgcccgc
    11221 cacgatcccg cagaacacgc acccgctcat ccgcccaccc taggcccggc ccgcccaccc
    11281 cacctccggg cgagcgttga tcatgaggtt ggcggcgaca aatcggacgg cgaccaccgt
    11341 caacctcatg atcgacgaga agaccggccg taggtcaggc gcgatcgagg taggcgtccc
    11401 agtcgtcgtc ggggatgccg gtcgggccgg tctcgccgtt ggcgaggcgc gcccggatgt
    11461 ccgcctccca ccgacgggcc cagcgcctga gtccgccgat ttcgtcctcg ccgagaccgt
    11521 aggaggcgaa tgtctccacg tcgagctcgt cgaccccgcc gagtcggtcg gccagctcgt
    11581 gaagcgaaaa cgcgacggtg tgctgggcgc ccaaggattc gagtcccgcg aactccacga
    11641 tccggctggc agcgcatacg tcgatgtagt cgcgatgcgc ggcgcggtcg tgaagcgccc
    11701 tgaccttgag gccgatggca tcctccagcg cgagcaccgg gccgatctgc aacctcgccg
    11761 gcggcccgat cgcctctttc aagaggtcga cctcgcaggc gaaaccctgc ccctcgacca
    11821 gcaaccgggc catccgcggc gtcgcctcaa cgacccggca gccgaattct ccggctcggt
    11881 acgcctcggc cagccgcgcc gccacgaggg gcagcggcaa cgcggttgcg gtggcgaagt
    11941 cgatgtcgcg ggacggtcgg ctcacgagat cgtgcgcggc gagtgcgtag ccacccgcga
    12001 gtaccagacc gaggtcgtca cccgcacgga atccgacgtg cagcaagcgc gtgtgcaact
    12061 cgtccacggc taggctgcca ggcccggcat tctgctctcc cagagtcgga tcacccggtg
    12121 cgcggtcagc ttgcggatgc gggaccagtc ctgccggagg agcgccgggt tgacgtaccg
    12181 gacgatgtcc tcgcgctgcc cgcagtccat cagcgtgcgg tagagcgtga gccgctgtcc
    12241 gctgtcgtcg acgtcgaact cgctgagccc ggaccacgcg aggcgggtcg gcagcgtgac
    12301 ccggccgcgc tcgggcccct tgaggtcgtc cagtgacgtg gggatccggt cggcgacgcc
    12361 gtgcaggcgg gaggggagcg cctcggtcgt actcaccgga ccagtatggc cgaccacccc
    12421 gacagagtcc tggttgtgac aggcgcgccc ggcctaccgg gagcaaaggg gaagcgggcg
    12481 gactaacgtc tgcggcatga ggcacggctt cgacacactc gccatccacg ccggtcaggc
    12541 cccggaggcc cgcaccggcg cggtgattcc gccgatctac cagaccagca cgtacgccca
    12601 ggacgccgtc ggcgcgccgc gcgagggcta cgagtacagc cgctccggca accccacccg
    12661 ggacgcgctc caggagtgcc tggccgcgct ggagggcggc caggtggggc tcgccttcgc
    12721 cagtggcctg gccgccgagg acacgctgct gcggaccgtc tgcaagccgg gcgaccacgt
    12781 ggtgatcccg gacgacgcgt acggcggcac ctaccggctg ttcgccaagg tggccgagcg
    12841 ctgggggctt gactacaccc cggcgaaggt ctccgacccg gacgccgtgc gcgcggcgat
    12901 ccgcccgggc gccacccgga tcgtgtgggt ggagacgccg accaacccgc tgctcggcat
    12961 cgccgacatc gcggcgctgg ccgccgtggc gcacgacgcc ggcgcgctgc tggtggtcga
    13021 caacacgttc gcctcgccgt acctgcagca gccgatcgcg ttcggcgcgg acgtggtggt
    13081 gcactccacc accaagtacg tcggcggaca ctccgacgtg gtcggcggcg cgctcgtcgc
    13141 ggcggaccgg gcgctcggcg aggagctgcg ttaccaccag aacgcgatgg gcgcgatcaa
    13201 cggcccgttc gacgcctggc tcaccctgcg cggcatcaag accctcgggg tacggatgga
    13261 ccggcactgc gacaacgccg agcggatcgc ggcctacctg gacggccacg cgcaggtcgc
    13321 gcaggtcatc tacccgggcc tgccctcgca ccccggccac gaggtggccg ccaagcagat
    13381 gcggcggttc ggcggcatga tctcgttccg cgcggcgggc ggcgaggagc acgccgtgga
    13441 catctgcaac cgatcccggc tgttcgtgct cgccgagtcg ctcggcggcg tcgagtccct
    13501 gatcgagcac ccgggccgga tgacacacgc aagcgctgcg ggctcgccgc ttgaagttcc
    13561 cggcgatctc gtgcgactgt ctgtcggcat cgagacggtc gacgacctgc tcgccgatct
    13621 ggagcaggcc ctgggctgac cgctggctgg ggagggtggc agtgccggag atcttgccga
    13681 cgacgtgggt cggtgcgacc gcgaaacaga tcgcccgggc ggtacgccgt ggcgacgtct
    13741 ccgccaccca ggtcgtcgcc gaccacctgg atcacgtcac ccgggtcgac gccgacctgg
    13801 ccgcgttccg cacggtacgc ggcggtgagg cgatcaccga ggcggagaag gtcgacgagc
    13861 aggaggaact ggcgaacctc ccgctcgccg gcgtgccggt ggcggtcaag gagaacacgc
    13921 cggtggccgg cctgcccacg tggaacgggt cggccgccat gcgtacaccg gtggcggagg
    13981 ccgaccacga ggtggtccgg cggctgcgcg gagcgggcgc ggtgatcctg ggcgtgaccc
    14041 ggatgccgga actgggcctg tgggcgctca ccgacgacga caccgctgcc acccgcaacc
    14101 cgtgggatcc ggcgcgtacc cccggcggct cctccggcgg cgcggccgcc gcggtggccg
    14161 ccgggctggt gccgatggcg cacggcaacg acggcctcgg gtcgatccgc atcccggcgg
    14221 cctgctgcgg cctggtcggg ctcaagcccg gccggggcgt ggtgccctgc cagctcggcg
    14281 cggacgactg gttcggcctg accgagcacg gcatgctcac cagcaccgtg gccgacgcgg
    14341 tggtcggttt ctcggtgctg gccggccgcc ggccggacaa gctggtcccg ccggcgcggc
    14401 tacgggtcgg cgtctcgctg cgctcgccgg tgcgcggcgt ctcgccggac gccccgaacc
    14461 gggacgcggt ggccgcggcc ggccgcctgc tcgccgccgc cggtcacgac accgtgccca
    14521 ccgacccggt ctacccgacc cggctcggcc tgcagggcat cgccacctgg ttcgcggcgg
    14581 ccgccgccga cgtgcgcgcc gccggggtcg ccccgcgcca gctccagcgc cgcagccgcc
    14641 ggcacgtcac gctcggcgag tgggcgcagc gccgggggta cgtgcgggag gccgaccggg
    14701 cggcctggcg cgaacggtcg gtgaacttct tcgcggacaa ctcgatcgac ctgctgctca
    14761 ccccggcgct ggccgggccg ccgccggagg ccgccggctg gtccggccgc tcc
//
