LOCUS       NZ_CP118233            24740 bp    DNA     circular CON 13-JUL-2024
DEFINITION  Micromonospora chalcea strain 1K05785M01 chromosome, complete
            genome.
ACCESSION   NZ_CP118233
VERSION     NZ_CP118233.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora chalcea
  ORGANISM  Micromonospora chalcea
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Study on the Growth Characteristics and Drug Resistance Related
            Proteins of Micromonospora chalcea MCCC 1K05785
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2023) Tianjin University, Tianjin University,
            Weijinlu Nub92, Tianjin, Tianjin 300072, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2022
            Assembly Method                   :: CLC NGS Cell v. 5.29
            Assembly Name                     :: TJU-micro-1.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028768405.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 23:01:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,224
            CDSs (total)                      :: 6,161
            Genes (coding)                    :: 6,110
            CDSs (with protein)               :: 6,110
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 51
            CDSs (without protein)            :: 51
            Pseudo Genes (ambiguous residues) :: 0 of 51
            Pseudo Genes (frameshifted)       :: 16 of 51
            Pseudo Genes (incomplete)         :: 40 of 51
            Pseudo Genes (internal stop)      :: 2 of 51
            Pseudo Genes (multiple problems)  :: 7 of 51
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:37:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5393431
            Orig. end                         :: 5418171
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP118233.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24740
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="24"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24740
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24740
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14740](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14740
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(79..94)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.52"
                     /tool="antismash"
     gene            1052..4495
                     /db_xref="GeneID:91359339"
                     /locus_tag="PVK74_RS24295"
                     /old_locus_tag="PVK74_24295"
     CDS             1052..4495
                     /codon_start=1
                     /db_xref="GeneID:91359339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020520250.1"
                     /locus_tag="PVK74_RS24295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_24295"
                     /product="M28 family peptidase"
                     /protein_id="WP_233514608.1"
                     /transl_table=11
                     /translation="MATQSTAATPPPTPTVAQSPLSLAISAADRAADGGHDALAKGPFE
                     QYDRRMVIPWVDGLFSIAYTRTYRGLPVVGGDAAVLADGKGAIRAISAATKTKINVSVV
                     PTVAVDRAEQTAKSLLAKVDRVESRTLVVHVKDSTARLAWEVVVAGRTASAPSHLHVFV
                     DARTGQVLAKQEDAAAGSGTGKWNGPSPLSITTSQSGSTYYLRDTTRTGLNCQDYSTST
                     VFSGADDSWGNGVGTSKETGCVDALYSAQKEWDMLSAWLGRNGHNGNGGSWPIKVGLNE
                     QNAYWDGSTITIGKNSAGNWISSMDVVGHEFGHGLDQNTPGGTSSEAGLGEATGDIFGA
                     LTEAYANQSATYDDPDYLVGEEIDLVGSGPIRNMYNPSLVGGHPNCYSSSIPNTEVHAA
                     AGPLNHWFYLLAEGSAPGGGKPNSPICSGGPSSVTGVGIQSAGKIFYGGMLLKTSGMTH
                     KKYRTATLTAAKNLDSSCVLFNRTKDAWNAVAVPAQTGDPTCTATSTDFSMSISPTSGG
                     VNAGSSVTATVNTATVSGSAQTVSLTSSGAPSGVTVSFSPSSVTSGGSSTMTVATTSGA
                     AAGTYTITVTGTGSVTHTAQYTLTVNGGTPGGTAPDIDVANVQAHLTQLSTIATNNGGT
                     RRSTGQGYLQSVAYVKGKLQAAGFTVTEQPCTSGCTSGAGPNLIAEWPGGNASNVYMFG
                     AHLDGVSAGPGMNDNGSGSAALLEVALALAAQNPTMLNKVRFGWWTDEEQGLNGSKFYV
                     NSLTSTQRTAIKAYYNFDMIASKNGGYFINNITSTASQPMKAYWDSLSLQPEENVEGQG
                     RSDDYSFQNAGIPTSGYAMGASATKTSAQASKWGGTAGQSYDSCYHSSCDTLSNIDATA
                     LNRAADGIAYTLWNRAVGTSTPTNDFSISASPASGTVNAGSSTTTTVGTATTSGSAQTV
                     TLTASGAPTGVTVSFSPSSVTSGSSSTATIAVGSSVAGGTYTITITGAGSVSHSTTYTL
                     TVTGGPGGCTAAQLILNGGFESGTSPWTGSTGVIGTSIGQVPRSGTRYAWLGGNGYTAT
                     EAISQTVTIPSGCTSAVLTYWLHIDTSEYWALAYDVFTIKANGTTVASLSNMNAATGYT
                     QRTVNLGAYAGQTVTLTFTGTEDAYLQTSFVLDDVTLQIG"
     gene            complement(4918..5466)
                     /db_xref="GeneID:91359340"
                     /locus_tag="PVK74_RS24300"
                     /old_locus_tag="PVK74_24300"
     CDS             complement(4918..5466)
                     /codon_start=1
                     /db_xref="GeneID:91359340"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PVK74_RS24300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PVK74_24300"
                     /product="hypothetical protein"
                     /protein_id="WP_274477301.1"
                     /transl_table=11
                     /translation="MPLLLAGYAGAAATAAWHLGPVTAMTVTTTLVVQDPVDAYELFAH
                     ARTTLGLPLDGRWHLVDHGHVHMLQTLPGQGAPALASVHFSVDGSRHPGEPDAGIPGGY
                     ALLAFTTDSADTNRTQRRHRDLAGQTGAWLTHRRLRWTWSHADGPFTTNHAGPIRRGFS
                     NDLATRGQIVDLFGGLRGP"
     gene            6089..7561
                     /db_xref="GeneID:91359341"
                     /locus_tag="PVK74_RS24305"
                     /old_locus_tag="PVK74_24305"
     CDS             6089..7561
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359341"
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /locus_tag="PVK74_RS24305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_24305"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_051611166.1"
                     /transl_table=11
                     /translation="MIDRQDLQQARDDLGRKLAALRRSRGLIQEALARQVHTTRSTLGM
                     VERGRQVVDRIFWLQCDTLLDAQGELLAAYDAYRHLQSRFQAQQAEAAQRARWGAVPEA
                     VMAAGEATGERYGEVGDNRRPPDRFHGERPEAGRTTRTGQVSVVNAVAGRGEEADHDAR
                     SRLLAELRRHLLAPAAPKQPVEPLTLSEVRQRVAHLHSLYQRGNYAEAVRALPDTFEQA
                     NLLTRTCTGTQRALAVGSLAAANLAAAKLTVKLGDPSLAWVAADRAARVAAEQAEDVAL
                     VAAAAFSVGTALLAMPDRVGDAEEVVLAALDGVTDTRDSASTGPRVLSAHGALTLLAAL
                     IAARQAQPAAVERHLDDANALARRLGADRNDLWTGFGPTNVMIHRISIAARTDQPQLAI
                     HLGEQLDTSSLPAALVSRRARVHLDLAAAYACSPGNDPAAVLHLLEAERIAPQTVHVHG
                     RTRHLIGDLLTRERRAVTPGLRALAERAGIAA"
     gene            7558..8100
                     /db_xref="GeneID:91359342"
                     /locus_tag="PVK74_RS24310"
                     /old_locus_tag="PVK74_24310"
     CDS             7558..8100
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359342"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018586217.1"
                     /locus_tag="PVK74_RS24310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_24310"
                     /product="flavoprotein"
                     /protein_id="WP_046569670.1"
                     /sec_met_domain="Flavoprotein (E-value: 1.8e-13, bitscore:
                     49.0, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSGSANARLLYLVVCAAPPARRIVELVEAVRRDGWDVYVIATET
                     AHTWLPNDRLAAVTGRPVSYRQRHPDEPSVLPRADAVAVVPATFNTINKWATGINDSLA
                     LGILNEALGAGMPIIVSPYVKPTLARHPAFDAHLRLLADHGVRLTATEALRPAHDDQPF
                     RWNVILDELHRLSARLS"
     misc_feature    complement(8478..8496)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.64"
                     /tool="antismash"
     gene            8533..9771
                     /db_xref="GeneID:91359343"
                     /gene="fxlM"
                     /locus_tag="PVK74_RS24315"
                     /old_locus_tag="PVK74_24315"
     CDS             8533..9771
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359343"
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018725297.1"
                     /locus_tag="PVK74_RS24315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_24315"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_338020349.1"
                     /sec_met_domain="PCMT (E-value: 2e-26, bitscore: 91.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVDTMSSDDLRDAMVDQLVADHAAKGLTMRPEVEAALRVVPREL
                     YTPGVPMEEAYRSDTAVVTKRLGDETVSSVSAPWLIAEMLGQAADALTGGLHGRHVLEI
                     GSGGYNASLLRELVGPSGSVTTVDIDPEVTERAVACLAVAGYGDVSVVCADAEQPIDLG
                     RCYDLIIVTAGAWDIPAAWIAQLAEDGVLVVPLRTFGMTRSWALRRVGDRLVSHSQRLC
                     GFVAMRGTGAHEMRYVDIAAGVHLRLDEGQQVDPESVGGLLSQPQEQAWAGVGLPPRSV
                     LADLDLWLAARLADEVDQFVVLSAQQEAVDAGIVAPAWRFGTPAALHEGTFSYRSTLRW
                     TDDTFDLGACAHRPDAAAAAGRMAGHMRAWVDAGEPSPVLHVLPAGTPDGALPAGTVLD
                     KRHSRLVLTFTSA"
     gene            9795..9932
                     /db_xref="GeneID:91359344"
                     /locus_tag="PVK74_RS24320"
                     /old_locus_tag="PVK74_24320"
     CDS             9795..9932
                     /codon_start=1
                     /db_xref="GeneID:91359344"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018588904.1"
                     /locus_tag="PVK74_RS24320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_24320"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_082159628.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 2.1e-14, bitscore:
                     51.6, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELEEFDLDITLVDAGPAASGYATSTDDGCGSGNTGSNACSGGSK
                     "
     misc_feature    complement(9995..10006)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     gene            10001..12742
                     /db_xref="GeneID:91359345"
                     /locus_tag="PVK74_RS24325"
                     /old_locus_tag="PVK74_24325"
     CDS             10001..12742
                     /codon_start=1
                     /db_xref="GeneID:91359345"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018831025.1"
                     /locus_tag="PVK74_RS24325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_24325"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_274477303.1"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 5.7e-13,
                     bitscore: 47.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.3e-94, bitscore:
                     315.3, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.5e-14, bitscore:
                     52.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFPTAGAALIRVAAYPSGLTLPAWPDLTTDQPEQWRQWLAAVWAL
                     PGFATAVAAATPQLAEQITRTVASAPTTDRRFGRMVDSTVRYLLRWTTRATPFGTFAGV
                     APVEFGARASVRWGEAHQVVTRPDGTFVAEHTGRAEQDLAALRDVAVVTNSVGYQRGEV
                     WVLPCLRGDGDRRWDIEIRLTRPVRAAIRAARSPVMFGDLAARVAGPLPAATGAAERML
                     ASLVQAGVLLSALRPATTVTDPASHLARHVPMPDPGDRVAVDLRVDASVTLPPAVLHEA
                     ARAASTLVAVAAPLPGWAEYHGAFIQRWGPGAAVPLRDVLNVLGFPAGYRGSTRRVPAV
                     FTARDRLLAQLAQQSALNDCTEVILDDELTGRLRGDDDRPPIPHTELRFTLAAATPQDL
                     DRGAFTLTVVSGARHAGVAAGRFLHLLSPAELASFRHVYRNLPTALPGADTVQLSGPPL
                     DARLAAVARTPAVLPVLPVGDFHPDPPWTLADLAVTGDGQRLWLVSRTSGRPVEPLLLN
                     SVLLPDLQQPLMRFLTEIWTAWTAPCSRFDWGHARSLPFLPRLRRGRSIVHPARWTIDR
                     TALPARTLAWSHWRDAWQRYREQHRLPDEVLVGADDVQVRLDLNDNTHLAVLRRHVDRH
                     ARTTLTEAPGPAGWIGGRPAELLLTLAHTRPATHPSRPARAVTAQQHRPGQSPWLEARL
                     YGRADDILTDLAHRTGNLPAAGWWFLRYPDPEPHLRLRIPLQDTTFAATAACLAEWAQQ
                     LEHKRVLHDYSLRTYRPETRHGTGPTLTAAEAVFAADSRATLQRLTGDRQASTAATMIA
                     IADAFTGDGPRWLAEHVPHHRGPRLEPVQLDLARTPYRDDDLDKALATYRTLAHADNLD
                     LDQVLTDILHLHHARMIGVDPASERHCLRLARAVARTRQATP"
     aSDomain        10454..10714
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_PVK74_RS24325_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.60E-15"
                     /identifier="RREFam001.1"
                     /label="PVK74_RS24325"
                     /locus_tag="PVK74_RS24325"
                     /protein_end="238"
                     /protein_start="151"
                     /score="47.9"
                     /tool="antismash"
                     /translation="VTNSVGYQRGEVWVLPCLRGDGDRRWDIEIRLTRPVRAAIRAARS
                     PVMFGDLAARVAGPLPAATGAAERMLASLVQAGVLLSALRPA"
     misc_feature    10949..10951
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12739..13815
                     /db_xref="GeneID:91359346"
                     /locus_tag="PVK74_RS24330"
                     /old_locus_tag="PVK74_24330"
     CDS             12739..13815
                     /codon_start=1
                     /db_xref="GeneID:91359346"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018831026.1"
                     /locus_tag="PVK74_RS24330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_24330"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_043325490.1"
                     /sec_met_domain="LANC_like (E-value: 1.1e-36, bitscore:
                     124.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAQSLAEGAAGVALLHLETGNRPAAHAALRAATANGVSIAAGA
                     SLFYGAPALAFVLATPNQPGLTRARSIAATGTATVTRRRLHAAHRRIDSHQRPHYAEYD
                     LIRGLTGLGVALHRLGDHDLLRQVLTYLVRLTEPVNDLPGWWCANGPDRHQPPPPGGHA
                     NHGIAHGITGPLALLALTHRAGITVDGHTEAILRICRWLDTWQQHTADTIWWPQTLTLD
                     DLHHGAPAQQHPLRPSWCYGTPGIARAQQLAALALHDTARQLLAETAFTTCVNDPAQIR
                     RLTDRSLCHGTAGLLATGRRIAADALTPTPLAPLTRLHLHATPAADEPTGLLDGTAGHA
                     LAAASTTSTSWDACLLLS"
     gene            13829..14740
                     /db_xref="GeneID:91359347"
                     /locus_tag="PVK74_RS24335"
                     /old_locus_tag="PVK74_24335"
     CDS             13829..14740
                     /codon_start=1
                     /db_xref="GeneID:91359347"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018817829.1"
                     /locus_tag="PVK74_RS24335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_24335"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_069089169.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.3e-23, bitscore:
                     82.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKETPWQQVNITYPGQSRHEREQHAIPHLHRVLPAAETAGLITSW
                     WFIRKGPWRIRYLPTTPDTDPGPVHDLLTGTRAWTSDIYEPEIHAFGGPDAMDTAHTLF
                     HHDSRHLLTYLHHQPADRRERSLILCTALMRATGLDLNEQGDVWARVARHRLEHRTWPP
                     AADPATWEAFTGKVRHLQLGTTRTTSDWQTAFENAGTALRHLRDTGKLTRGLRAVIAEH
                     VIFHWNRIGIPATTQAVLAQAAAEAIFGRAPVPPGEQWPRPVEPVPPSAVPPTEVDAPS
                     RAALASSRHSRLLTEGASAQWS"
     gene            complement(16453..17334)
                     /db_xref="GeneID:91359348"
                     /locus_tag="PVK74_RS24340"
                     /old_locus_tag="PVK74_24340"
     CDS             complement(16453..17334)
                     /codon_start=1
                     /db_xref="GeneID:91359348"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012515.4"
                     /locus_tag="PVK74_RS24340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_24340"
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="WP_051611164.1"
                     /transl_table=11
                     /translation="MSHQLPDQVRTPHVAFVGRANIDITVRIPQRPVAGRTTFASSPAT
                     TTPGGKSLNQALAARQAGVRASLITNVGDDEWGASLSRALTNAAIDMSFLQVVPSAPTG
                     TAIIEITPDGENYIVLAHSTETELASEHVRNALQQLRAPIVVTQLDLQPDAVDAVFRHH
                     HAETLIGNLVPHPSLGLTALAPLDLFVSNEAEAAAILGRHHANPSIAAQELRKLGPRAV
                     VVTAGARGAAYSDADHTALVPASHVKAINTSGAGDAFLGTLAARLAHNVPLPHAVAKGV
                     AAATTFVQVDRR"
     gene            complement(17331..18836)
                     /db_xref="GeneID:91359349"
                     /locus_tag="PVK74_RS24345"
                     /old_locus_tag="PVK74_24345"
     CDS             complement(17331..18836)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359349"
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /locus_tag="PVK74_RS24345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_24345"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_046569661.1"
                     /transl_table=11
                     /translation="MIDPQRVDDAKRALGARLAAWRNVRGLTQLALARRVPVSRTTIAG
                     VERGQQCPDRIFWQRCEAALAAGGELLADYDDYRRLKQQLDQEKVEAAQRMRWGEVEDR
                     SLPAGTHGVPVTDPARESLRDLAATDLTAGGPNGLTAPLARVAGAAVAGETDFHDGDAV
                     TLAVMSDGQAMSLRVSRRALLELAAGLTAVPVVTTTGVSHPRSVDPAVVDHFAELRALL
                     VQADDLLGGLTILSTVEQQIALIAALRRQTRGQLRNRLLSTEARWSEFAGWLSDDLGDR
                     AAGDRWLDRAGSMAQEADDQEFWAYVLTRKAQRMVGTGDEDCVVGLARAASRLPDTPPL
                     LHAFAAIQQAHGSAIAQDASAFQAAVERAHTLVATARPPSGGSSALGSFCTRPYLAAQE
                     GEGWLRLNQPRRAIDSFTNAVNTWPDRYRRERGVYLSRTAHAYLAASEPGQAATVAAEA
                     LTTATTTGSVRVRRNVTTLARRLEPFSSQPEVRQLLDQLATSG"
     gene            complement(19466..20779)
                     /db_xref="GeneID:91359350"
                     /locus_tag="PVK74_RS24350"
                     /old_locus_tag="PVK74_24350"
     CDS             complement(19466..20779)
                     /EC_number="2.7.7.49"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359350"
                     /inference="COORDINATES: protein motif:HMM:NF012307.4"
                     /locus_tag="PVK74_RS24350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_24350"
                     /product="reverse transcriptase family protein"
                     /protein_id="WP_128136113.1"
                     /transl_table=11
                     /translation="MTTNHALATALADAFLAGKGWRRADLVDQGGLVLGVRRRWLWPVA
                     DAVLAAYPRPPTDRPRELATFLSTLDPLRAAVAAARQHQRPIVLHTRPVTPTRTVRRPW
                     HNPVIDTVGDLAATLDLSIEYLDWYADRRAMNRRATAHRLHHYHYRWTAGGRLIEAPKS
                     RLRALQRRLLTEVLGPIPVHPAAHGFVPGRSAHTFAAAHTAQPVVVRIDLLAFFTHIPA
                     TRAYGLFRTAGYPEPVAHTLTGLCTTRTPNPVLRRAPTDLPERAARLAALRTGHLPQGA
                     PTSPALANLCAYRLDRRLTGLADAFEITYTRYADDLAFSGDLTTRRIHDLIAAVTHIAR
                     DEGFEVHTGKTRVRGRADRQLLAGLVVNHHPATPRDDYDRLRAILHNAARTGLAAQNRT
                     GHPDFAQYLIGRVAWVGHHHPARAAKLTALLAQALAAP"
     gene            21065..21601
                     /db_xref="GeneID:91359351"
                     /locus_tag="PVK74_RS24355"
                     /old_locus_tag="PVK74_24355"
     CDS             21065..21601
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359351"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018818837.1"
                     /locus_tag="PVK74_RS24355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_24355"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_091113549.1"
                     /transl_table=11
                     /translation="MMDVDDEELLRLVGKGDRGAFDVLYARNAPWLVLRLRRRCRDPEL
                     VREVVQETFLTVWRAAAGYRGDGAAVGWLWSVAAGRLIDARRRALARPQSVGVPGDDVL
                     AWSPSAEDEVLAGAYDAELERALHRLAPELRAVLQATVLDGLTVREAAVLLGVPEGTVK
                     TRAMRARRELRAALS"
     gene            21598..22383
                     /db_xref="GeneID:91359352"
                     /locus_tag="PVK74_RS24360"
                     /old_locus_tag="PVK74_24360"
     CDS             21598..22383
                     /codon_start=1
                     /db_xref="GeneID:91359352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018731528.1"
                     /locus_tag="PVK74_RS24360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_24360"
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="WP_091113552.1"
                     /transl_table=11
                     /translation="MTGFHVDAGVLAAYVEGRLADVDAWSVEAHLDRCAACRTSIASDA
                     STASVVEAVAVSLGGRLPRQGRVRRATGWRRIRVLVGAGPAARAAWLLSVAVTGVLTAG
                     LAVSPTVVPPWLLLLIAPALPAVGTALSYGPRTDPLHELIAGTPQGGLRIVLWRTLAVL
                     AVAAPVAVLAGAVTGIGTPGWWLLPCVALTALTLALGSLVEPAYAALVVAGAWAVVVLA
                     PPVGGLAVLVSAGPGWLGVTAAAAAVVYVRRERVGRQPA"
     gene            22380..23135
                     /db_xref="GeneID:91359353"
                     /locus_tag="PVK74_RS24365"
                     /old_locus_tag="PVK74_24365"
     CDS             22380..23135
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359353"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019870615.1"
                     /locus_tag="PVK74_RS24365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_24365"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_091113556.1"
                     /transl_table=11
                     /translation="MTTVSVDGLRVSYGKRIVLDDLDLDLGVGVHGLLGPNGAGKTTLM
                     RVLATVLRPDRGEVRLLGHHLGDPSALRQARRQLGYLPQAFGFYPRFTVREFVEYFAWL
                     KEMPPARIPLAVDRVIERVGLLERADDRMKHLSGGMLRRAGIAQAIVNDPRLLLLDEPT
                     AGLDPEQRVQFRALLRELGLDAVVLVSTHLVEDVVAACTRVNLVDRGRLVFTGLPDELI
                     AAGGDGDSGDSPIERGYTAVLRGARTAPR"
     gene            23132..24400
                     /db_xref="GeneID:91359354"
                     /locus_tag="PVK74_RS24370"
                     /old_locus_tag="PVK74_24370"
     CDS             23132..24400
                     /codon_start=1
                     /db_xref="GeneID:91359354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019870616.1"
                     /locus_tag="PVK74_RS24370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_24370"
                     /product="hypothetical protein"
                     /protein_id="WP_338020350.1"
                     /transl_table=11
                     /translation="MRRALRVELRRGTAPLAAVAMFGAGVWMLAVHPDDWAGRWAGLAN
                     YLRVSLLILCALMIAAGAWQSGRERRRDIDELIASTPRPGWQPLVMAWFAVTVAGVAGL
                     LVAFAGAAVLVARVATYAGGGWWWTLTVGVLALAAAAAIGVLVGRLVPLRVAAPIAGLA
                     TYLGLAIITYWDGTPGAWLSPVYGGWAVYSRVPGRITALQAAWLVALTVLLLAAAARQQ
                     RAALLAGGLAVAVPITTGPGTHRLPADPAAVELVCTSSGPQMCLSRINAFLIDDVATVV
                     QPILGRLDGIPGAPRRAADQAAQPAGQSIERDDGTVWLNLDYQSTALGGLASRKNLRAD
                     FRQVTRTRCEDPSGTRNIDMRVYRTDTLATDWMLDEAATPDDVPLTVLRALPEPAQRSW
                     FAAYLDAAHRCDIPALIRLGEQP"
ORIGIN
        1 gcgaccgtca acagttcctg aacttcggcc gacacagtgc ccagccattc gttcaccagt
       61 cggcgggcgg ccggcggcag gaccaggtcg tctacgagac cctgagcggc cggcaggtcg
      121 gtggcgcggc tgcgggcccc ggcgaatgcg agggctaggg ccgggttccc tccgctgcgg
      181 atgtgggtct gcgtgacctc gtagggggtt agccggtacg gcgacagcag ggttgcgacc
      241 tgatcgggtg tcagcgccgg gatgcgtacc gcacaggggt cctcgccgca ccagtggcct
      301 tcgctccccg ggcgccagat tcgctctgcg gctatgacgg gaaggtcggg agccaggcgc
      361 agtgcccaac gcaagacggc cgcgctggcc gtatccagcc actgggcgtt gtccaccacc
      421 agtgtcagag gcggggtgtc cagcagcagg gtggcggtca accggcgcag ccgtagagcg
      481 gtcccggcgg gatcggcaga gcccggcact ccgacggcct tgtcgattcc ggtcgcgagt
      541 tcccgcgcgg ccggcagcgg ttggagggcc agtgcgagtt cgagcagtcc ggtgtagggg
      601 acctgggcgt cctgtgggct cggagccagc cttaggacag gcatgcccag ctgctgcccg
      661 agtacaccgg ccgcagcggt cttgccgatc ccgggcggac cgaacagcac cacccgacgg
      721 gcgccgcgca cgacgcccgg taccaccggc agcatggtgc cggtggcccc ctgatgcgca
      781 ttcactgccg tcgcagaatc tggcaccgga tcatagtgcg cccgacggtc cttcgcgcac
      841 cagagcaagg ggttgccctg atttcggcca gcctccgccg ttcctagtgt catcgccaaa
      901 gccgagctgt caccggttgc cggagatccc atcaacacgg gccctgctgc cacacccctc
      961 aacccatctc ggcgggagga ttgcgatgta tcgaagaact gccatggcgg ccgctgtcgc
     1021 ggttgcgctt accctgggca ccgtgaccgg ggtggccacc cagtcgaccg cagccacccc
     1081 gccccctaca cccacggttg cgcagagccc gctgtcgctg gcgatctccg cggccgaccg
     1141 ggccgccgac ggcggtcacg acgcgctggc gaaaggcccc ttcgagcagt acgaccggcg
     1201 catggtgatc ccgtgggtcg acgggctgtt ctccatcgcc tacacacgca cctaccgggg
     1261 cctgccggtg gtcggcggcg acgccgccgt gctcgccgac ggcaagggcg cgatccgggc
     1321 gatctcggcc gccaccaaga cgaagatcaa cgtgtcggtg gtgccgacgg tcgccgtcga
     1381 ccgtgccgag cagaccgcca agagcctgct cgcgaaggtc gaccgggtcg agtcgcgcac
     1441 cctggtggtg cacgtcaagg acagcaccgc ccgcctcgcg tgggaggtcg tcgtcgccgg
     1501 gcgcaccgcc tcggcgccca gccacctgca tgtcttcgtg gacgcgcgca ccggccaggt
     1561 gctggccaag caggaggacg ccgcggccgg ttccggcacc ggcaagtgga acgggcccag
     1621 cccgttgtcg atcaccacgt cgcagtcggg cagcacgtac tacctgcgcg acaccacgcg
     1681 caccggcctg aactgccagg actacagcac cagtaccgtc ttctccggcg cggacgacag
     1741 ctggggcaac ggggtgggca ccagcaagga gaccggctgc gtcgacgcac tgtactcggc
     1801 gcagaaggaa tgggacatgc tgtcggcctg gctgggccgc aacgggcaca acggcaacgg
     1861 tggcagctgg ccgatcaagg tcggcctgaa cgagcagaac gcctactggg acggctccac
     1921 gatcacgatc ggcaagaact cggcaggcaa ctggatctcg tcgatggacg tggtcggcca
     1981 cgagttcggc cacggcctcg accagaacac ccccggcggc accagctccg aagccggcct
     2041 cggcgaagcc accggcgaca tcttcggcgc cctgaccgag gcatacgcca accagtccgc
     2101 cacctacgac gacccggact acctggtcgg tgaggagatc gacctcgtcg gcagcggccc
     2161 gatccgcaac atgtacaacc cttcgctggt cggtggccac ccgaactgct actcctcgtc
     2221 gatcccgaac accgaggtac acgcggccgc cggcccgctc aaccactggt tctacctgct
     2281 cgccgagggc agcgcgccgg gcggcggcaa gccgaacagc cccatctgct cgggcggccc
     2341 gtcgtcggtc accggcgtcg gcatccagtc cgccggaaag atcttctacg gcggcatgct
     2401 gctcaagacc tccggcatga cccacaagaa gtaccgcacc gcgaccctga ccgccgcgaa
     2461 gaacctggac tcctcgtgcg tcctgttcaa ccggaccaag gacgcgtgga acgcggtcgc
     2521 ggtcccggcc cagaccggcg acccgacctg caccgcgacc agcaccgact tctcgatgtc
     2581 gatcagcccc acctcgggcg gcgtcaacgc gggctcctcg gtgaccgcga cggtcaacac
     2641 cgccaccgtc tccggcagcg cgcagaccgt gtcgctgacc tcctcgggtg ccccgtcggg
     2701 ggtcaccgtg tcgttcagcc cgtcgtcggt cacctcgggc ggcagctcca cgatgacggt
     2761 ggcgaccacg tccggcgcgg ccgcgggcac gtacaccatc accgtgaccg gcaccgggtc
     2821 ggtcacccac acggcccagt acacgctgac ggtcaacggc ggcacccccg gtggcaccgc
     2881 gccggacatc gacgtcgcca acgtgcaggc gcacctgaca cagctcagca ccatcgccac
     2941 caacaacggc ggcacccgcc gctcgaccgg ccagggctac ctgcagtcgg tggcgtacgt
     3001 caagggcaag ctgcaggccg ccggcttcac cgtcaccgag cagccctgca cctccggctg
     3061 caccagcggt gcaggcccga acctgatcgc cgagtggccg ggcggtaacg cgagcaacgt
     3121 ctacatgttc ggcgcccacc tggacggcgt ctcggccggt ccgggcatga acgacaacgg
     3181 ctccggctcg gcggcgctgc tcgaggtcgc cctcgcgctg gccgcgcaga acccgaccat
     3241 gctgaacaag gtccgcttcg gctggtggac cgacgaggaa cagggcctca acggctccaa
     3301 gttctacgtc aactcgctga ccagtaccca gcgaacggcg atcaaggcct actacaactt
     3361 cgacatgatc gcgtcgaaga acggcggcta cttcatcaac aacatcacct cgaccgcgtc
     3421 gcagccgatg aaggcgtact gggactccct cagcctgcag ccggaggaga acgtcgaggg
     3481 ccagggccgt tccgacgact actcgttcca gaacgcgggc atcccgacct ccggttacgc
     3541 gatgggcgcc agcgccacca agacgtcggc ccaggcgtcg aagtggggcg gcacggccgg
     3601 tcagtcctac gactcctgct accactcctc gtgcgacacc ctcagcaaca tcgacgccac
     3661 cgcgctgaac cgggctgccg acggcatcgc ctacacgctg tggaaccggg cggtcggcac
     3721 ctcgacgccg accaacgact tctcgatctc ggccagcccc gcgtcgggca ccgtgaacgc
     3781 ggggtccagc accacgacca ccgtcggcac cgccaccacc tcgggcagcg cccagacggt
     3841 taccctgacc gccagcggcg cccccacggg cgtaacggtc tcgttcagcc cgtcgtcggt
     3901 cacctccggc agctcgtcga ccgccaccat cgcggtcggc tcgtcggtgg ccggcggcac
     3961 ctacaccatc accatcaccg gcgcgggttc ggtgtcgcac agcaccacgt acacgctgac
     4021 cgtgaccggc gggccgggcg gctgcaccgc cgcccagctg atcctcaacg gcggtttcga
     4081 aagcggcacc tcgccgtgga ccggctccac cggcgtgatc ggcacctcta tcgggcaggt
     4141 gccgcgcagc ggcacccggt acgcgtggct cggcggaaac ggctacaccg cgaccgaggc
     4201 catcagccag accgtcacca tcccgtcggg ctgcaccagt gcggtactga cctactggct
     4261 gcacatcgac acgagcgagt actgggcgct cgcctacgac gtgttcacga tcaaggccaa
     4321 cggcaccacc gtggcgtcgc tgtccaacat gaacgctgcc acgggctaca cgcagcgcac
     4381 cgtcaacctc ggcgcgtacg ccggccagac ggtcacgctg accttcaccg gcaccgagga
     4441 cgcctacctg cagaccagct tcgtgctgga cgacgtgacc ctgcagatcg gctgagttca
     4501 acggcagggt ggggcgctcg ccccaccctg ccgcaggtcc tgcgcccctg ttccgctgcc
     4561 ggaccggacc ttagcctgaa tccgtggatt ggattctggg tgcgttgtcg ggttgatcta
     4621 gccgattggg ggtgtgatgg atccgctggc cctggtctcc gtagaacgcc aagtaacccg
     4681 gctccgcctt gacctggcga gaggcgaagt ccatcgcctc cgggcgcaga tctgcccaac
     4741 ctcgcgggaa gcggccgtac cggtcgtaga acctccgcaa cagcgcgaac ccggccgtat
     4801 ctcgccatgc ttggacgcaa ccaggtccag ctcagcaggg acaagggtcc agtgctcgac
     4861 cagctcgccg atgctcagag gagatcgact cacagcggtc aaccatcgtg gcagcgatca
     4921 gggaccgcgc agacccccaa aaagatcaac tatttggccc ctggtcgcaa gatcgttact
     4981 aaagcccctg cggatggggc cggcgtggtt ggtcgtgaag ggcccgtcgg cgtgtgacca
     5041 ggtccagcga agccgtcggt gggtcagcca cgcgccggtc tggccggcga ggtcgcggtg
     5101 ccggcgctgg gtcctgttgg tgtcagcgct gtcggtggtg aaggcgagca gggcgtagcc
     5161 gccggggatc ccggcgtcgg gctcgccggg gtgccggctg ccgtcgacgg agaagtgcac
     5221 gctagccagg gccggtgcgc cctgtccggg cagagtctgc agcatgtgga catggccgtg
     5281 gtcgaccagg tgccatcggc cgtccagggg cagcccgagc gtggtgcggg cgtgggcgaa
     5341 cagttcgtag gcgtcgacgg ggtcctgcac gacgagggtg gtggtcacgg tcatcgcggt
     5401 caccgggccc agatgccagg ctgcggtggc ggcggcaccg gcatacccgg cgagcagcag
     5461 cggcacggcg cgggagatgg cggcgtactt ggcccgtacg gcgcgggaaa gccaccacaa
     5521 ctcgccggcg cgtgcgaggg ggtcgtctgg gcggccgggt cggtgtcgcc gccgacaacg
     5581 cgggccagaa cgtcctgggc ggtgtcggtg tcggcgtagg cgacgaaccc gaagtcccca
     5641 ccccgaaatc ccggtacgcg aaacccgcgt ccggcaccgg tggggctact gaaccgccga
     5701 aagcccctgc ggcagggctg gcgccgcgcg ccctttatgg gcatcaccgc acgctcttcc
     5761 gcgctcgtcg aagagggccg atgcccaccg aactcgcaca tcgtgtccgg ggtgtctgtc
     5821 ggtgacggcg gcaggctgag gttgccgtgc ccgttgggcc gggagtgggg atggctgaag
     5881 tgtgttccgc cgtgatcgtg gctgacgttc gaggtgccaa ccccgctccc cggttttcga
     5941 cacaggcgcc ctctctgcca ggccagcacg ccattcgcac cagctccacg cccaggtcgc
     6001 gtgcgatccg ctaacgtcga atcgccgtgc gtcggggcgc cgcaacagtc ggctcgacgc
     6061 aggtcgatgc gaacggaaag gcgagcccat gattgatcgc caggatcttc aacaggccag
     6121 ggacgatctc ggccgtaagc tcgccgccct gcgtaggtcg aggggactca ttcaggaagc
     6181 cctcgcacgc caggtgcaca cgacgcgcag caccctggga atggtcgagc ggggccggca
     6241 ggtcgtggac cggatcttct ggctgcagtg cgacaccctg ctggacgccc agggcgagct
     6301 actcgccgcc tacgacgcct accgacacct ccagtcccgg ttccaggcac agcaggccga
     6361 ggcggcacag cgggcgcggt ggggagcggt acccgaggcg gtgatggcag ccggcgaggc
     6421 cacaggcgaa aggtacggcg aagtcggcga caatcgacgc ccgccggacc ggttccacgg
     6481 cgagcgcccg gaggcgggcc gcaccacacg aaccgggcag gtctcagtcg tcaacgcggt
     6541 agcaggccgt ggcgaggaag ccgaccacga tgccaggtcg cgactgctgg ccgagctgcg
     6601 ccggcacctg ctcgcacctg ccgcaccgaa acagccggtc gagcctctca cgctttcgga
     6661 ggtccgtcag cgggtggccc atctccatag cctttaccag cgtggcaact atgccgaggc
     6721 ggtccgggcg ttgcccgaca cgttcgagca ggcgaacctg ttgacccgga cctgcaccgg
     6781 cacgcagcgc gccctggccg tcgggtcgct ggcggcggcg aatctcgccg ccgccaaact
     6841 caccgtgaaa ctcggcgatc ccagccttgc ctgggtggcg gcggaccgtg ccgctcgtgt
     6901 cgccgccgag caggccgagg atgttgcgct cgtcgctgcg gcggcgttct cggtgggtac
     6961 tgcgctgctg gcgatgccgg accgcgtcgg cgatgccgag gaggtggtgc tggccgctct
     7021 cgatggtgtg acggacacga gggactccgc gtcgacgggt ccgcgtgtcc tgtcggccca
     7081 cggggcgttg actctgctcg cggcgctgat cgccgcccgg caggcccagc ccgccgctgt
     7141 cgagcggcac ctcgacgacg cgaacgccct ggcccggcgg ctcggcgccg atcgtaacga
     7201 cctgtggacc gggttcggtc cgacgaacgt gatgatccac cgcatcagca tcgccgcccg
     7261 aacggaccag cctcagctgg cgatccacct tggagaacag ctcgacacct cgtcgctgcc
     7321 ggcggccctg gtgagccgcc gcgcccgggt ccacctcgac ctcgccgccg cctacgcctg
     7381 ctcgcccggc aacgatcccg cagccgtgct gcacctgctc gaagccgaac gcatcgcgcc
     7441 gcagacggtg cacgtgcacg gccggacgcg ccatctgatc ggcgacctgc tcacccgtga
     7501 gcggcgcgcc gtcacccccg gcctgcgggc actcgccgaa cgcgccggaa tcgccgcgtg
     7561 acgtccggat ccgcgaatgc ccgtctgctc tacctggtgg tctgtgccgc gccaccggcc
     7621 cgccgcatcg tcgagctggt cgaggcggtg cggcgcgacg gctgggatgt gtacgtcatc
     7681 gcgaccgaaa ccgcgcacac ctggcttccc aacgatcggc tggccgccgt tacgggcagg
     7741 cccgtcagct accggcagcg gcatcctgac gaaccgagcg tcctgccacg cgccgatgcc
     7801 gtcgcggtcg ttccggcgac gttcaacacc atcaacaagt gggccaccgg catcaacgac
     7861 agtctggccc tcggcatcct caacgaagct ctcggcgcag gcatgccgat catcgtctcc
     7921 ccgtacgtca aacccaccct cgcccgccac cccgcgttcg acgcccacct gcggctcctc
     7981 gccgaccacg gcgtacgcct caccgccacc gaggcgctgc gaccagctca cgacgatcag
     8041 cccttccgct ggaacgtgat cctcgacgaa ctccacaggc tgtccgcccg cctgtcgtag
     8101 tcggcccccg agaggcgctg gggccggtct gaccgtgtcg aaatcccgtg tcgagggtgt
     8161 tcgacacggt cagaccggcg ttgagtggtg gacatgaccg ctcggcgccc gccgctcagg
     8221 ggtccccggc accgcccaac ccgaggggag ttgatccgtg tgaccctgta ccgcagtttc
     8281 tcgccgctgc cgaggaatcc gggaccgctg gtggccggga cggctcggac ctcacgttga
     8341 ctgcggcttg atcgaacccg ggccgccttg cgtcgccttg ccggttgggc acccggtgag
     8401 ttcggcctgc gtcctgccca gcaggggaac agtcctcggg cgtctgaggc cgtgttcgtc
     8461 cttggcggat aacggaaagt gcgggccgtc cgcaacggcg gcggtcctga cgaacaggag
     8521 agtgacgcgc acatgagcgt cgacacgatg agcagcgacg acctccgtga cgcgatggtc
     8581 gaccagctgg tcgctgacca tgcggccaag gggctgacga tgcggcccga ggtcgaggcg
     8641 gcactgcggg tggttccccg cgagctgtac acgccgggtg tcccgatgga ggaggcgtac
     8701 cgcagcgaca ccgcggtcgt caccaagcgg ctcggtgatg agaccgtcag ttcggtgtcc
     8761 gcgccgtggc tgatcgcgga gatgctcggg caggcggctg acgccctcac cggtggcctg
     8821 cacggccggc acgtgctgga gatcggatcg ggcggctaca acgcgtcgct gctgcgcgag
     8881 ctggtcgggc cgtcgggttc ggtcacgacc gtggacatcg acccggaggt gaccgagcgg
     8941 gcggtggcgt gtctggcggt ggcaggttac ggcgatgtca gcgtggtgtg cgcggacgcg
     9001 gagcagccga tcgacctggg gcgctgctac gacctgatca tcgtgacggc cggggcgtgg
     9061 gacatccccg cggcgtggat cgcgcagctc gccgaggacg gcgtgctggt ggtgccgcta
     9121 cggacgttcg ggatgacccg gtcgtgggcg ctgcgccggg tcggtgaccg gctggtcagc
     9181 cacagccagc gcctctgcgg gttcgtggcg atgcggggca ccggagccca cgagatgcgg
     9241 tatgtcgaca tcgccgccgg tgtccacctg cggctggatg agggccagca ggtcgacccg
     9301 gaatcggtcg gtgggctgct gtcgcagccg caggagcagg catgggcagg ggtgggcctg
     9361 ccgcctcgta gcgtcctggc cgacctggac ctgtggctgg cggcccgcct cgccgatgag
     9421 gtcgaccagt tcgtggtgct ctcggcgcag caggaggccg tcgacgccgg catcgtcgcc
     9481 cctgcctggc ggttcggtac gcccgccgcc ctgcacgagg ggacgttctc ctaccggtcg
     9541 acgctgcgct ggaccgacga cacgttcgac ctcggcgcct gcgctcacag gcccgacgcc
     9601 gccgcggcgg cgggacggat ggccgggcac atgcgcgcgt gggtggacgc tggcgagccc
     9661 tctccggtgc tgcacgtcct acccgcaggt actcccgacg gcgccctgcc ggccgggacg
     9721 gtgctggaca agcgacacag tcgcctcgtc ctcaccttca cctccgcata ggaaggaaca
     9781 cgcgagtgga gaccatggaa ctcgaggagt tcgacctgga catcaccctg gtggacgccg
     9841 gccccgctgc cagcgggtac gccaccagca ccgacgacgg ctgcggctcg ggcaacacgg
     9901 gctcgaacgc ctgttccggc ggcagcaagt aaccgtccct gacgatccac cccgggcccg
     9961 gcgtctccag cgccgggccc ccgtcttcga gggtgcgttc atgttcccca cggccggtgc
    10021 ggcgctgatc agagttgccg cctaccccag cggtctgacc ctgcccgcgt ggcccgacct
    10081 gacgacggat cagcccgagc agtggcggca gtggctggcc gcagtgtggg cgctgccggg
    10141 attcgccacc gccgtcgccg ctgccacacc ccagttggcc gaacagatca cccggaccgt
    10201 ggccagtgcg ccgaccaccg accgccggtt cgggcgcatg gtcgactcga cggtccggta
    10261 cctgctgagg tggaccaccc gggcgacacc gttcggcacc ttcgccgggg tggctccggt
    10321 cgagttcggc gcccgcgcat cggttcggtg gggcgaggcg catcaggtgg tgacccgccc
    10381 tgacgggacg ttcgtcgccg agcacaccgg gcgcgccgag caggacctgg cggcgctgcg
    10441 cgacgtcgcg gtggtgacga actcggtggg gtaccagcgc ggcgaggtgt gggtgctgcc
    10501 ctgcctgcgc ggcgacggcg accgcaggtg ggacatagag atccgtctga ccaggccggt
    10561 gcgggcggcg atccgcgcgg cgcgttcccc ggtcatgttc ggtgacctcg ccgcccgggt
    10621 cgccgggccg ctgcccgccg ctaccggggc ggccgaacgg atgttggcgt cgctcgtcca
    10681 ggcgggtgtc ctgctgtcgg cgctgcggcc ggcgacgact gtcaccgacc cggcctccca
    10741 cctggcccgt cacgtcccga tgcccgatcc cggcgaccgg gtcgcggtcg acctgcgtgt
    10801 cgacgcctcg gtgacgctgc caccggcggt gctccacgag gcggcccgtg ccgcgtcgac
    10861 gctggtggcg gtggcagcgc ccctgccggg atgggcggaa taccacggcg cgttcattca
    10921 gcggtggggc ccgggcgcgg ccgtgccgtt acgcgacgtc ctgaacgttc tgggctttcc
    10981 cgccggatac cggggttcca cccggcgtgt acctgcggtg ttcaccgccc gcgaccggct
    11041 cctcgcgcag ctcgcccagc agtcggcgct gaacgactgt acggaggtga tcctcgacga
    11101 cgagctgaca ggccgcctac gaggagatga cgaccggccg ccgatcccac acaccgaact
    11161 acggttcacc ctcgccgccg cgaccccaca ggacctggac cgaggcgcgt tcacgttgac
    11221 ggtggtcagc ggagcccgcc acgccggggt cgccgccggc cggttcctgc acctgctttc
    11281 tcccgccgag ctggcgtcgt tccggcacgt ctaccggaac ctgccgaccg ccctgcccgg
    11341 cgcggacacg gtgcaactgt ccggcccgcc gctggatgcc cgcttggccg cggtcgcccg
    11401 gacacctgcg gtgctgcccg tcctgcccgt cggcgacttc cacccggacc cgccgtggac
    11461 gctcgcggac ctcgcggtga ccggcgacgg ccagcggctg tggctggtgt cgcggacctc
    11521 cgggcgaccg gtcgagccgc tgctgctcaa cagcgtgctg ctacccgacc tccagcagcc
    11581 cctgatgcgg ttcctgaccg agatctggac ggcgtggacg gctccgtgca gccgattcga
    11641 ctgggggcac gcgcgtagcc tgccgttcct gccacgcctg cgacgcggac gcagcatcgt
    11701 gcaccccgcc cgctggacca tcgaccggac cgcgctcccc gcccgcaccc tggcatggtc
    11761 ccactggcgc gacgcctggc agcgataccg tgaacagcac cggctcccgg acgaggtcct
    11821 ggtcggcgcc gacgacgtgc aggtacgtct ggacctgaac gacaacaccc acctggcagt
    11881 gctgcgccgg cacgtcgacc ggcacgcccg caccaccctc accgaggctc ccggcccggc
    11941 cggctggatc ggcggccgac ccgccgaact cctcctcacc ctcgcgcaca cccgtccggc
    12001 cacccacccg agccgaccag cgcgggccgt gaccgcacaa cagcatcggc ccggccagtc
    12061 accgtggttg gaggcccgcc tgtacggccg ggccgacgac atcctcaccg acctcgccca
    12121 ccggaccggc aacctcccgg cggcgggctg gtggttcctc cggtacccgg accccgagcc
    12181 ccacctgcgg ctacgcatcc cactccagga caccaccttc gctgccaccg ccgcatgcct
    12241 cgccgaatgg gcgcaacaac tggagcacaa acgcgtcctg cacgactaca gcctgcgcac
    12301 ctaccggccc gagacccgcc acggcaccgg ccccaccctc accgccgccg aagcggtctt
    12361 cgccgctgac tcccgcgcca ccctgcagcg gctgaccggc gaccgccagg ccagcaccgc
    12421 cgccacgatg atcgccatcg cggacgcctt caccggcgac gggccgcgtt ggctcgccga
    12481 acacgtcccc caccaccgcg gcccccgact cgaacccgtc cagctcgacc tcgcccgcac
    12541 cccctaccgc gacgacgacc tggacaaggc actggccacc taccggacac tggcccacgc
    12601 cgacaacctc gacctcgacc aggtactgac cgacattctg cacctgcacc acgcccgcat
    12661 gatcggcgtc gaccccgcct ccgaacggca ctgcctccgc ctggcccgcg ccgtcgcccg
    12721 cacccgccag gcgacgccgt gaccgcagca cagtccctcg ccgaaggggc ggccggcgtc
    12781 gcccttctac acctggaaac cggcaaccgg cccgccgccc acgcggcact gcgggccgcc
    12841 accgccaacg gcgtcagcat cgccgcaggc gccagcctct tctacggcgc acccgcactc
    12901 gccttcgtcc tcgccacccc caaccaaccc ggcctcaccc gagcacgatc gatcgccgcc
    12961 accgggaccg ccacggtcac ccgccgacgg ctgcacgccg cccaccgccg catcgactcc
    13021 caccagcggc cccactacgc cgagtacgac ctcatccgcg gcctgaccgg cctcggcgtc
    13081 gccctgcacc gcctcggcga ccacgacctg ctccgccagg tactcaccta cctggtccgg
    13141 ctcaccgaac cggtcaacga cctccccggc tggtggtgcg cgaacggacc cgaccgacac
    13201 cagccaccac caccaggagg ccacgccaac cacgggatcg cccacggcat caccggccca
    13261 ctcgcgctac tcgccctcac ccaccgcgcc ggcatcaccg tcgacggaca caccgaggcg
    13321 atcctgcgga tatgccgatg gctggacacc tggcagcagc acaccgccga caccatctgg
    13381 tggccgcaga ccctcaccct cgacgacctg caccacggcg cacccgcaca acaacaccca
    13441 ctacgcccct cctggtgcta cggcaccccc ggaatcgccc gcgcccaaca actggccgcc
    13501 ctcgccctgc acgacaccgc ccggcagctc ctcgccgaga cggcgttcac cacctgcgtg
    13561 aacgaccccg cacagatccg ccgtctcacc gaccgcagcc tctgccacgg caccgccggc
    13621 ctcctcgcca ccggccggcg catcgccgcc gacgcactca ccccgacacc cctcgcccca
    13681 ctgacccgcc tccacctgca cgccaccccc gccgcggacg aacccaccgg actacttgac
    13741 ggcacagccg gtcacgccct ggccgcagcc tccacaacct caacctcgtg ggacgcctgc
    13801 ctcctactca gctgacgaaa ggcccgccat gaaggagacc ccctggcaac aggtgaacat
    13861 cacctaccct ggccagagcc gccacgaacg cgaacaacac gcgatacccc acctccaccg
    13921 cgtcctaccc gccgccgaga ccgccggcct catcacctcc tggtggttca tccgcaaagg
    13981 accgtggcgc atccgctacc tgcccaccac gcccgacacc gaccccggcc cggtacacga
    14041 cctgctcacc ggaacgcgcg cctggaccag cgacatctac gaacccgaga tccacgcctt
    14101 cggcggcccc gacgcgatgg acaccgcaca caccctgttc caccacgaca gccgccacct
    14161 cctcacctac cttcaccatc agccggcaga ccgacgggaa cgctccctca tcctgtgcac
    14221 ggcactcatg cgcgccaccg gactcgacct caacgaacaa ggcgacgtat gggcgcgagt
    14281 cgcccgacac cgcctggaac accgcacctg gccccccgcc gccgaccccg ccacctggga
    14341 agccttcacc ggcaaggtcc gtcacctgca actcggcacc acccgcacca ccagcgactg
    14401 gcagaccgcc ttcgagaacg ccggcacagc cctccgccac ctacgcgaca caggaaaact
    14461 cacccgtggg ctacgcgccg tgatcgcaga gcacgtgatc ttccactgga accggatcgg
    14521 gatacccgcc acaacccagg ccgtcctcgc ccaagcagcc gcggaagcca tcttcggccg
    14581 tgcccccgtg ccgccaggcg agcagtggcc acgcccggtc gaacccgtac caccatctgc
    14641 ggtaccgcca acagaggtcg atgcgcccag tcgcgcggcg cttgcaagtt caagacacag
    14701 cagactcctc acagaggggg ctagtgccca atggtcgtga agcgctggcg gggccggaca
    14761 catcgtccgg ccccaagtaa agtgctggtg cgtgatggtt gaaccgcttc ggtcgatcct
    14821 ggccttggcg tccgaagtgt gcagtcgggc cagttatcgc cgacctttcg tcacgattgc
    14881 cctaactgct agaaggatca acgggaccag tatcggtgta ggcacggaaa tggcgtcggg
    14941 aatttcattc accgaagcgg caacccatgt aaccgctgcg gcgattgcgg ctaccagtag
    15001 cccggatagg gttagggcgt gtcgagccgt tcgcttcgaa ggcagaaact ttatctcaat
    15061 ggcgaatcgc caccaggttg cgaagaaatt cccttccgtt gatctttctg ttcggtgatg
    15121 cgcccagacg cgtgccttgt ccgacggttc ggactcgatg gggtcagtgt gatcggccag
    15181 gttgagctct tggtcaatct gctgggacgg gcaacgcccc tggttcactg cataacccca
    15241 atcgtgcaag cgaacaagct tcacttcctt cctgcgtgtt ggatcgggtg cggtcgctgt
    15301 gcataaagac tgaccgacat gggtcgtagg acgagactcc taggcccatt gtcatggtct
    15361 caacgtgcat cgcaagaccc gtcgcacatg gtgtgcgatg ttccagcttg gagggacggt
    15421 tgactagcag ccctgaaccc gtgagtctgt tgacgggcgc ccattggtaa cgcgaagtgt
    15481 cttaaatttt cctgggaact gtcagcagcg ataaagagta ccgggcatgg gagaagggga
    15541 tatatatgcc agcgaagggg tctgttgaag cgggcaatgg cggcgttccg aaacggcgtg
    15601 agtccgatgg cggcatcacc cctccggcag ttgcgtctgg aggtgcgagt gggagcagcg
    15661 ggccgctaac ccgtgtaacc gtcaatttta ctcaaaggtc aatgttggcg ctcgatagtg
    15721 ccgtccggaa gtcgggagat accagaacgg acaccatcaa ccgcgcaatt caagtatatg
    15781 atctagtgca agatgtccta aagcgcggcg atggccgaag cctgctgatc aagtatccga
    15841 atggcgaatg cgagcgcctg ctaatgatgt gactagccgc tcggctctta acgcattcgg
    15901 gcagatgttg gacttgaatg gcaccaattc ttcccaaggg tagagcagga gcagtcaccg
    15961 ccgggtatag aaagtaggca gggctgacca tctcgcggcg gcggccattg gcgacacggc
    16021 tgctggggaa agtccattcc gtctgtccgt tgtagtcgtg gccgcgcgca gcgctgcatt
    16081 atcctgcctt ggaggccctc ttgccggcga gaccccttgc ggcatcgttg taaacccctg
    16141 tgctcgtaat cgacggagcg tcgctcgtcg actttgccgg cttcgtctac gagttctcgc
    16201 agctgctctg tcacgcaacc cgagcggaag cctcgatgcc ttcagcgaca tcctcttcga
    16261 gcaggaccct gggaggctgg ccgttctgct gaccgcagtc ggtgtgccag gcatgccgct
    16321 gccagaggcc ttgtcggata cgcactcgag ttcgaaccga tcgtccctcg cgatcttgtg
    16381 gagactcgga tcagtgcggg cgtctggcaa ccatgaaggc cagcgatgtc accgtcgtcc
    16441 cgacctagtc gcctagcgtc tgtcgacctg cacgaaggtt gttgcggcgg cgacgccttt
    16501 ggcgactgcg tggggtagcg gcacgttgtg agcgagtcgt gcggcgaggg tgccgaggaa
    16561 ggcgtcaccg gccccgctgg tgttgatggc cttgacgtgt gatgcgggga cgagtgcggt
    16621 gtggtcggca tcgctgtagg cggcgccgcg agcgccagcg gtcaccacca ccgctcgtgg
    16681 gcccagcttg cggagttcct gcgctgcgat cgacggattg gcatggtggc ggcccagtat
    16741 cgctgccgct tcggcctcgt tcgaaacgaa caggtcgagt ggggccaggg cggtcagacc
    16801 gagcgaggga tgtggcacga ggttgccgat gagcgtctct gcgtggtgat gccggaagac
    16861 ggcgtcaacg gcatcgggct ggagatcgag ctgggttacc acgatcggag ctcgtagctg
    16921 ctgaagtgcg ttgcgcacat gctcgctggc gagctcagtc tctgtggagt gtgcgaggac
    16981 gatgtagttc tcgccgtcgg gggtgatctc gatgatcgcg gtaccggtcg gagccgatgg
    17041 cacgacttga aggaaggaca tgtcgatggc cgcgttggtg agggctcggc tcagggaggc
    17101 gccccattcg tcgtcgccga cgttggtgat caggctggcg cggacgcccg cttgtcgtgc
    17161 ggccaaagcc tggttgaggc tcttgccgcc cggtgtggtc gtcgcgggtg acgaggcgaa
    17221 cgtcgtccgg ccagcgacgg gccgttgggg gatccgcacg gtgatgtcga tgttggcgcg
    17281 gccgacgaag gcgacatgcg gcgtacggac ctgatcgggt agttggtgac tcatccgctg
    17341 gtggccagct ggtcgaggag ctgtcgcact tccggctggc tggagaaggg ttcgagtcgc
    17401 cgggccaggg tggtgacgtt tcggcggacc cgaaccgagc ccgtcgtggt agccgtggtc
    17461 aacgcttcag ccgcgacggt ggcggcctgg cctggttccg aagccgccag gtaggcgtgc
    17521 gccgtgcggg agaggtacac gccccgttcg cgtcggtagc ggtcgggcca cgtgttgacg
    17581 gcgttggtga agctgtcgat ggcccgacgc ggttggttga ggcggagcca tccctcgccc
    17641 tcctgcgccg caaggtacgg ccgggtgcag aacgaaccga gggcactgct tcccccgctc
    17701 ggcggcctgg cggtcgccac gagtgtgtgg gcacgctcga ccgcggcctg gaaagcggag
    17761 gcgtcctgcg cgatggcgct gccgtgcgcc tgctggatgg cggcgaaggc gtgcaggagc
    17821 gggggcgtgt cgggcaggcg ggaagcggca cgggccagcc cgacgacaca gtcctcgtcc
    17881 ccggttccca ccatccgctg tgccttacgg gtcaggacgt acgcccagaa ctcctgatcg
    17941 tcggcttcct gcgccatgct tcccgcgcgg tccagccagc ggtcgcccgc ggcccggtcg
    18001 ccgagatcgt cgctgagcca acccgcgaac tcgctccacc gtgcctcggt gctgagaagc
    18061 cggttacgaa gctgtccacg tgtctgccga cgcagggcgg cgatcagcgc gatctgctgt
    18121 tcgacggtcg acaggatggt gaggccaccc agcaggtcgt ccgcttgtac gaggagcgcg
    18181 cgaagctccg cgaagtgatc gacaacggca gggtcgacgg accgtgggtg agaaacgcct
    18241 gtggtggtga caaccggcac ggcggtgagg ccagcggcca gttccagcag agccctccgg
    18301 cttacccgca atgacatcgc ctgcccatcg gacatgaccg caagcgtaac cgcgtcacca
    18361 tcgtgaaagt ccgtctcacc tgccaccgcg gcaccggcga cccgcgcgag tggtgccgtc
    18421 aggccgttcg gaccaccggc cgtcagatcc gtggcggcga ggtcgcgcaa cgactcccgt
    18481 gccggatccg tcaccgggac accgtgagtg ccagccggta gtgagcggtc ctcgacttcg
    18541 ccccaccgca tgcgttgtgc cgcttcgact ttctcctgat caagctgctg cttcaggcgc
    18601 cgatagtcgt cgtagtcggc cagcaactct ccaccagcgg ctagggccgc ttcacagcgc
    18661 tgccagaaga tccggtccgg gcattgctgc ccgcgctcga cgcccgcgat cgtggtccgg
    18721 gaaaccggca cccgcctcgc caatgccaac tgggtcagcc cacgcacgtt gcgccaggcg
    18781 gcaagccttg cacccagtgc ccgcttcgca tcgtctaccc gctgcggatc gatcatgacg
    18841 cccgtccctt cacaaccccg tacggacacg acggctgcat tgacgcaaag cgacgttacc
    18901 gtaaccgatc tccgccagaa ccggccagcg cctcaacaac cccggcgccg acgtccttgt
    18961 ccgcgccgag caacgtctat cggcgggcga cccgagaccc gactccggac cttcgatgat
    19021 gtgcgcggtg tgtgctcgag agcggatgcc accgtggggc aaccggtgcc accggatgcc
    19081 acggcgggtc aacgggccgg gtcgctgccg gggtccgtgt gctcggggtg tggtcatcgg
    19141 tcggccctga ccagggcgac gacgtgggtg aacgtgggcc actccctgcc accccgggtg
    19201 aaccggcagg ccgctagact gggcactcgc gccctcgtag ctcaggggat agagcatcgg
    19261 tttcctaaga cgacgctcta tctgtacccg gaggctgact acctgccggt tcctattctt
    19321 cttgcatatt aatgggtcgc acgcggtcct tgctgtgctc gcttgctgaa gatcagcaga
    19381 ataggcgtaa gtcctgctca ggtcctgcct cggtcggttc gacgcgtcct tgccaaatct
    19441 cgcgaagttg ccgcgccgcg tcagtctacg gtgccgcgag tgcctgggcc agtagcgcgg
    19501 tgagtttggc tgcgcgtgcc gggtggtgat gaccgaccca ggcaactcgc ccgatgaggt
    19561 attgggcgaa gtcggggtgg ccggtcctgt tctgcgcggc gaggccggtg cgggcggcgt
    19621 tgtggaggat ggcgcggagc cggtcgtagt cgtcgcgtgg tgtggcgggg tggtggttga
    19681 cgacgagtcc ggcgaggagt tgccggtcgg ctcggccacg gacacgggtc ttacctgtgt
    19741 ggacttcgaa gccctcgtcg cgggcgatgt gggtgacggc ggcgatcagg tcgtggatgc
    19801 ggcgggtggt gaggtcgccg gagaaggcga ggtcgtcggc gtagcgggtg taggtgatct
    19861 cgaaggcgtc ggcgaggccg gtgaggcgtc ggtcgagtcg gtaggcacac aggttcgcca
    19921 gcgcgggtga ggtgggcgcg ccttggggca ggtgaccggt gcgcagcgcg gcgagccgcg
    19981 ccgcccgctc cggtaggtcg gtgggtgcgc ggcgcaggac ggggttcggg gtgcgggtgg
    20041 tgcagagtcc ggtgagggtg tgggcgacgg gttcggggta gccggcggtg cggaacagtc
    20101 cgtaggcgcg ggtggcgggg atgtgggtga agaaggcgag caggtcgatc cggacgacga
    20161 ccggctgtgc ggtgtgggcg gcggcgaagg tgtgggcgga gcggccgggt acgaagccgt
    20221 gggcggcggg gtggaccggg atggggccga ggacctcggt gaggagccgg cgttgcaggg
    20281 cgcgcagccg ggacttcggt gcctcgatga gccggccacc cgcggtccag cggtagtggt
    20341 agtggtgcag ccggtgggcg gtggcgcgtc ggttcatggc gcgtcggtcg gcgtaccagt
    20401 cgaggtactc aatgctcagg tcgagcgtcg cggccaggtc gccgaccgtg tcgatgaccg
    20461 gattgtgcca gggacggcgg acggtgcggg tcggcgtcac tgggcgcgtg tggaggacga
    20521 tcggccgctg gtgctggcgg gcggcggcga ctgccgcgcg cagcgggtcg agggtgctca
    20581 ggaacgtggc gagctcgcgt ggccggtcgg tgggtgggcg tgggtaggcg gccagcaccg
    20641 cgtcggcgac cggccacagc cagcggcgtc gcacgccgag gacgagccca ccctggtcga
    20701 cgagatcggc acggcgccag cccttgccgg cgaggaacgc gtcggcgagc gcggtggcca
    20761 gggcgtgatt ggtggtcacg atcgggccga tggtggcagc gtgtcccgac gatgcccggt
    20821 cgtgcgggtg cacaggctcg cggagcgtgc cgacgcacct gtggtgtgct gccgaggtga
    20881 gtgtcgcgtc cccggggttg ccccggagag accgtgaccg gaccccgcgt gggggagcgg
    20941 cctggtcagc tcgggacacg ctgccatggg agcagcgtag agaacgcaga ccgtcatggg
    21001 tgtccgcgat gggtgtggcg cggtggagag aaccgtttcg ccgggtgatg cgtcctaacc
    21061 ttgcgtgatg gacgtggacg acgaggagct gttgcgtctc gtcgggaagg gtgaccgtgg
    21121 ggcgttcgac gtgctgtatg cgcgtaacgc gccgtggttg gtgctgcgtc tgcgccgccg
    21181 gtgccgggat ccggagttgg tccgggaggt ggtgcaggag acgttcctga cggtgtggcg
    21241 ggccgcggcc ggctaccgcg gggacggtgc ggcggtgggc tggctgtggt cggtggccgc
    21301 cggtcggttg atcgacgcgc ggcgtcgcgc gttggcccgt ccgcagagtg tgggggtgcc
    21361 gggcgacgac gtgttggcgt ggtctccgtc ggcggaggac gaggtcttgg cgggcgcgta
    21421 cgacgccgag ttggagcgtg cgctgcatcg gctggctccg gagttgcggg cggtgttgca
    21481 ggcgacggtg ctggacggtc tgacggtgcg ggaggccgcg gtgttgctgg gtgtgccgga
    21541 gggcacggtg aagacccggg cgatgcgggc gcgccgcgag ttgagggcgg ccctgtcatg
    21601 accgggtttc acgttgacgc cggggtgctg gcggcgtacg tcgagggacg tctcgctgac
    21661 gtggacgcgt ggtcggtgga ggcgcacctc gaccgctgtg cggcctgccg gacgagcatc
    21721 gcctcggacg cgtcgacggc ttctgtggtg gaggcggtcg cggtgtcgct gggcggccgg
    21781 ttgccgcggc aggggcgggt gcgacgggcg accgggtggc ggcggatcag ggtgttggtg
    21841 ggtgcggggc ccgcagcgcg ggcggcgtgg ttgctgtcgg tggcggtcac cggggtgctc
    21901 accgcggggt tggcggtcag cccgacggtg gttccgccgt ggttgctcct gctgatcgcg
    21961 ccggcactgc ccgctgtcgg tacggccctg tcgtacgggc cgcgaacgga tccgctgcat
    22021 gagctgatcg cggggacacc gcagggcggc ctgcggatcg tgctgtggcg cacgctggcg
    22081 gtcctcgcgg tcgccgcgcc cgtcgcggtc ctggccggcg cggtgacggg tatcggtacg
    22141 ccggggtggt ggctgcttcc ctgtgtcgcg ttgaccgcac tgacgttggc gctcggctcg
    22201 ttggtcgagc ccgcgtacgc cgcgctggtg gtggcggggg cgtgggcggt ggtggtgctg
    22261 gcgccgccgg tcggcggtct ggcggtcctg gtgtcggccg gcccgggctg gctgggcgtc
    22321 accgcggcgg ccgcggcggt ggtgtacgtg cgtcgggaac gcgtgggaag gcaaccggca
    22381 tgacgacggt gagcgtcgac ggcctgcggg tcagctacgg caagcggatc gtcctcgacg
    22441 acctggacct cgatctcggt gtgggggtgc acgggttgct cggcccgaac ggcgccggga
    22501 agaccaccct gatgcgggtc ctggccacgg tcctgcgccc cgatcgaggc gaggtgcggc
    22561 tgctgggcca ccacctcggc gacccatcgg cgttgcggca ggcgcgccgc cagttgggtt
    22621 acctgccgca ggcattcggg ttctacccgc gcttcaccgt gcgggagttc gttgagtact
    22681 tcgcctggct caaggagatg ccgccggcgc ggattccact ggcggtggac cgggtgatcg
    22741 agcgggtcgg tctgctggag cgcgccgacg accggatgaa gcacctctcc ggcgggatgc
    22801 tgcgccgcgc tggcatcgcc caggccatcg tgaacgaccc tcggctgctg ctgttggacg
    22861 agccgaccgc cggtctggac ccggagcagc gggtgcagtt ccgggcgctg ctgcgggagc
    22921 tgggcctgga tgccgtggtc ctggtcagca cgcacctggt cgaggacgtc gtggcggcgt
    22981 gcacccgggt caacctggtc gacaggggac ggctggtctt caccggcctc cccgacgagc
    23041 tgatcgccgc cggtggggac ggcgacagcg gcgactcccc gattgagcgc ggttacacgg
    23101 cggtgctgcg tggcgcgcgg acggcaccgc ggtgaggcgc gcgctgaggg tggagctacg
    23161 ccggggtact gcaccacttg ctgcggtggc gatgttcggt gccggagtgt ggatgctggc
    23221 cgtgcacccg gacgactggg ccggccggtg ggcgggcctt gccaactacc tgcgggtgtc
    23281 gctgctgatc ctgtgcgctc tcatgatcgc tgccggggcg tggcagtccg gcagggaacg
    23341 gcggcgcgac atcgacgagc tgatcgcctc caccccccgc ccgggctggc aaccactggt
    23401 gatggcctgg ttcgccgtca ccgtggccgg tgtcgccggg ctgctggtcg cgttcgccgg
    23461 ggcggcggtg ctggtcgccc gggtcgcgac ctacgccggc ggaggctggt ggtggacgtt
    23521 gaccgtcggt gtcctcgccc tggccgccgc cgccgcgatt ggcgtcctcg tcgggcggct
    23581 cgtaccgctt cgggtggcgg ccccgatcgc cggcctcgcc acctacctgg gcctggccat
    23641 catcacctac tgggacggca cgcccggcgc gtggctctcg cccgtctacg gcggctgggc
    23701 ggtgtactcg cgcgtccccg gccggatcac cgcgttgcag gcagcctggc tggtggccct
    23761 gacggtcctg ctgctcgccg ccgccgcacg gcagcagcga gcagccctgc tggccggcgg
    23821 actcgccgtc gccgtgccga tcaccaccgg cccgggcacc caccgcctcc cggccgaccc
    23881 ggccgcggtc gagctagtgt gcacgagcag cggcccgcag atgtgcctct cccggatcaa
    23941 cgcgttcctg atcgacgacg tcgccacagt cgtgcagccg atcctgggac gtctcgacgg
    24001 gatacccgga gcaccccggc gggcagccga ccaggccgcg cagccggccg gtcagtccat
    24061 cgaacgggac gacggcacgg tctggctcaa cctcgactac cagtccaccg ccctgggcgg
    24121 cctggccagc cgcaagaacc tgcgggcgga cttccggcag gtgacccgga ccagatgcga
    24181 ggacccctcc gggacacgca acatcgacat gcgggtgtac cggaccgaca ccctggccac
    24241 cgactggatg ctcgacgagg cagccacccc ggacgacgtg cccctcaccg tgctccgcgc
    24301 actgccggag ccggcgcagc gttcctggtt cgccgcctac ctcgacgccg cccaccgatg
    24361 cgacatcccg gcgctgattc gcctcggcga gcagccgtga ccagccgcct gctcacgctt
    24421 catctgcgct cccgcggcgc gaccacgttc gtggtcgatg tcggcgtcat cgcgctgctc
    24481 gcctgggccg ccggaacatg gctcgccagc cggccctact tcgacgggcc cgccgcccgc
    24541 gtccccgtgg tcgcactcgc accgctgctg gccgcactcc tgctcggccc caccctcgcc
    24601 ggcgccgacg aggacctcga acgcagcaca cccctgccgt ggcgggcctg gcgagccggt
    24661 cacctactcg tcgccgcctt cgtcaccgcc acggtgctca gccttgccgg actgcgggca
    24721 cccgacacgt acggtgcaca
//
