LOCUS       NZ_CP118233            20966 bp    DNA     circular CON 13-JUL-2024
DEFINITION  Micromonospora chalcea strain 1K05785M01 chromosome, complete
            genome.
ACCESSION   NZ_CP118233
VERSION     NZ_CP118233.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora chalcea
  ORGANISM  Micromonospora chalcea
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Study on the Growth Characteristics and Drug Resistance Related
            Proteins of Micromonospora chalcea MCCC 1K05785
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2023) Tianjin University, Tianjin University,
            Weijinlu Nub92, Tianjin, Tianjin 300072, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2022
            Assembly Method                   :: CLC NGS Cell v. 5.29
            Assembly Name                     :: TJU-micro-1.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028768405.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 23:01:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,224
            CDSs (total)                      :: 6,161
            Genes (coding)                    :: 6,110
            CDSs (with protein)               :: 6,110
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 51
            CDSs (without protein)            :: 51
            Pseudo Genes (ambiguous residues) :: 0 of 51
            Pseudo Genes (frameshifted)       :: 16 of 51
            Pseudo Genes (incomplete)         :: 40 of 51
            Pseudo Genes (internal stop)      :: 2 of 51
            Pseudo Genes (multiple problems)  :: 7 of 51
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:37:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5077531
            Orig. end                         :: 5098497
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP118233.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20966
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="22"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20966
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20966
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10966](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10966)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            184..1521
                     /db_xref="GeneID:91359028"
                     /gene="hemL"
                     /locus_tag="PVK74_RS22740"
                     /old_locus_tag="PVK74_22740"
     CDS             184..1521
                     /EC_number="5.4.3.8"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0042286 - glutamate-1-semialdehyde
                     2,1-aminomutase activity [Evidence IEA]"
                     /GO_process="GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (50-373). E-value: 2.6e-75.
                     Score: 245.5. Matches aSDomain:
                     nrpspksdomains_PVK74_RS22740_Aminotran_3.1"
                     /codon_start=1
                     /db_xref="GeneID:91359028"
                     /gene="hemL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012184519.1"
                     /locus_tag="PVK74_RS22740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22740"
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="WP_043327407.1"
                     /sec_met_domain="Aminotran_3 (E-value: 6.1e-85, bitscore:
                     283.8, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.5e-07, bitscore:
                     27.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETLSAGSGRYPADAPASEALFDRAKAVVPGGVNSPVRAFRAVG
                     GTPRFMVRGEGPWLFDADGRRYVDLVCSWGPLILGHAHPAVVEALREAATLGTSFGTPT
                     PGEVDLAEEIIARTPVEQVRLVNSGTEATMSAIRLARGFTGRSKIIKFAGCYHGHSDAL
                     LAAAGSGVATFGLPDSPGVTGAAASDTIVLPYNDLRAVEEAFAAQGQHIAAIITEAAAG
                     NMGVIAPRDGFNAELARIAHAHGALLIVDEVMTGFRVSRAGWHGLDPSDADLWTYGKVM
                     GGGLPAAAFGGRAEIMAKLAPAGPVYQAGTLSGNPLACAAGLATLRLADDALYRRLDET
                     SAALGKLTTEALSAAGVPHRLSTAGNMFSVFFTDADVRDYDSARTQVVPAFKAFFHAML
                     AGGVYLPPSAFESWFVSTAIDDAAWEQIAAALPVAARAAAAAGSGG"
     aSDomain        334..1302
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PVK74_RS22740_Aminotran_3.1"
                     /evalue="2.60E-75"
                     /label="PVK74_RS22740_Aminotran_3.1"
                     /locus_tag="PVK74_RS22740"
                     /protein_end="373"
                     /protein_start="50"
                     /score="245.5"
                     /tool="antismash"
                     /translation="MVRGEGPWLFDADGRRYVDLVCSWGPLILGHAHPAVVEALREAAT
                     LGTSFGTPTPGEVDLAEEIIARTPVEQVRLVNSGTEATMSAIRLARGFTGRSKIIKFAG
                     CYHGHSDALLAAAGSGVATFGLPDSPGVTGAAASDTIVLPYNDLRAVEEAFAAQGQHIA
                     AIITEAAAGNMGVIAPRDGFNAELARIAHAHGALLIVDEVMTGFRVSRAGWHGLDPSDA
                     DLWTYGKVMGGGLPAAAFGGRAEIMAKLAPAGPVYQAGTLSGNPLACAAGLATLRLADD
                     ALYRRLDETSAALGKLTTEALSAAGVPHRLSTAGNMFSVFFT"
     gene            1524..2171
                     /db_xref="GeneID:91359029"
                     /locus_tag="PVK74_RS22745"
                     /old_locus_tag="PVK74_22745"
     CDS             1524..2171
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /db_xref="GeneID:91359029"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454496.1"
                     /locus_tag="PVK74_RS22745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22745"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_013283542.1"
                     /transl_table=11
                     /translation="MAETVVHVLRHGEVHNPDGILYGRLPGFRLSELGVQMAKAAAQAL
                     ADRTVVHVVASPLERAQQTAEPIAAQFGLSVGVDERLIESANWFEGKKVSPGDGSFRDP
                     RNWWVLRDPVTPSWGEAYRAIAERMFAALHAARVAAEGREAVLVSHQLPIWTLRRHVER
                     KRLWHDPRRRQCGLASLTSFHFDGAKIVGIGYSEPAAHLVSISPTARTAKGA"
     gene            2171..2746
                     /db_xref="GeneID:91359030"
                     /locus_tag="PVK74_RS22750"
                     /old_locus_tag="PVK74_22750"
     CDS             2171..2746
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359030"
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012184517.1"
                     /locus_tag="PVK74_RS22750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22750"
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="WP_274477169.1"
                     /transl_table=11
                     /translation="MLTRRLAAALLAAVTAGTALVGCSSGNQESRCAADGSVVTCAPDQ
                     RSKTPKVSGELLTGGGYDISRDRGQVVVVNFWGSWCAPCRAEADDLEDTYQATKGSGVT
                     FLGINVQDSKDKALAFEEGRVTYPSIFDPASRQALNFDIPPNTTPATVVLDREGRIAVV
                     IRRAVTRDELRPIVEKIAAESPAPNGAR"
     gene            2746..3612
                     /db_xref="GeneID:91359031"
                     /locus_tag="PVK74_RS22755"
                     /old_locus_tag="PVK74_22755"
     CDS             2746..3612
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018821807.1"
                     /locus_tag="PVK74_RS22755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22755"
                     /product="cytochrome c biogenesis protein CcdA"
                     /protein_id="WP_064448401.1"
                     /transl_table=11
                     /translation="MGETFRQLAESGPLLFAVGAAALAGLVSFLSPCVLPLMPGYLSYV
                     TGLAGADLEGARKGPLLTPPVEEGPLVNSGGASGGGVGVAERAAPARTTAAVKGRVLAG
                     TLLFIAGFTVVFVATAILFSGVGKLFFRYERTLEIVIGALVVVLGLGYLGVIPGMQREF
                     RIRWLPSAGLLGAPVLGAVFALSWLPCTGPTLGAVLGMAATEGGTDRAVVLAVAYCLGL
                     GIPFVVFGLGFQRLLGVFRAVRRNSRWVTRIGGALLIAIGLALISGGWVNVVIWLQTNV
                     GVGEVSI"
     misc_feature    2929..2931
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3612..5231
                     /db_xref="GeneID:91359032"
                     /locus_tag="PVK74_RS22760"
                     /old_locus_tag="PVK74_22760"
     CDS             3612..5231
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283545.1"
                     /locus_tag="PVK74_RS22760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22760"
                     /product="cytochrome c biogenesis protein ResB"
                     /protein_id="WP_274477170.1"
                     /transl_table=11
                     /translation="MTTVDDRPSTPPAQAPRRRVNPVLALLRNSWRQLTSMRTALILLF
                     LLAVAAIPGSVLPQRGVNPERVNQWFVDHPDLAPRLDQIGAFEVFGSVWFSAIYLLLFT
                     SLIGCILPRARDHVRALRMKPPAAPKRLERLPQHTVLEAPAAADPEAIAAVLRGRRWRV
                     TVRGNEVSAEKGYLKETGNLLFHVSLVAVLLGVALGSWYGWHGNRILVAGEDNAFCNTR
                     QQYAEASLGPRVDSADLPPFCLTLEKFEADYLPSGLASRYWATVTVDEPGGTARTAGFS
                     VNSPLRLGSANVYLLGNGYAPLLKYTDKYGRSQTSEAPFLRTGDSNATEEGVAIFPDAN
                     VDPKTGARSPDQQIAFDGLYLPTGPESAPYVASQYPAERNPMVNLTAYRGNLGMDAGIP
                     GSVYALDRRQIDDGKLKEIGTKLLRPGEKWTLDDGSTLEFVGTKPYITLAVRHAPGQTL
                     LLVASGTLLLGLMGSLFARRRRVWFRVSPPEGVSPTGGSSLVEAGGLPRTEHPGFADEF
                     AQLVAAVSGDAPDARRAREGDE"
     gene            5231..6196
                     /db_xref="GeneID:91359033"
                     /gene="ccsB"
                     /locus_tag="PVK74_RS22765"
                     /old_locus_tag="PVK74_22765"
     CDS             5231..6196
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /GO_process="GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359033"
                     /gene="ccsB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283546.1"
                     /locus_tag="PVK74_RS22765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22765"
                     /product="c-type cytochrome biogenesis protein CcsB"
                     /protein_id="WP_064448403.1"
                     /transl_table=11
                     /translation="MSALSDQLVAYAILVYLIAMISHAVEFALGNARKVPAAAPARELV
                     GAGVGGAGGTVDEPAAPPRPDHSAARAVLAGRIAGWLTAVAAAVHLGAVITRGVAADRM
                     PWGNMYEFVLTGTWIGVAAWLVVLWKQPWLRRLGLFLTLVMVLLLAFAELKLYVPIEPL
                     MPALQSWWFIIHVSTIIFASGLFLLGVVPAAAYLMRAGWEQGRRSFPYTLARRLPAAAG
                     LERLTFTLHAFSFPIFTFAVIAGAIWAEAAWGRAWGWDPKETWAFISWVVYAGYLHARA
                     TPSVKRNVATWISIVGFLTVMMNLFGVNFFFTGLHSYAGV"
     gene            complement(6165..6389)
                     /db_xref="GeneID:91359034"
                     /locus_tag="PVK74_RS22770"
                     /old_locus_tag="PVK74_22770"
     CDS             complement(6165..6389)
                     /codon_start=1
                     /db_xref="GeneID:91359034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787858.1"
                     /locus_tag="PVK74_RS22770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22770"
                     /product="hypothetical protein"
                     /protein_id="WP_043327397.1"
                     /transl_table=11
                     /translation="MDDAYVVGDPDGLSPLQAEIRDAVARELHAQFALRADRLELADLP
                     EVAYQVTRRVDEVLSARPATTPRRTSADR"
     gene            complement(6434..6904)
                     /db_xref="GeneID:91359035"
                     /locus_tag="PVK74_RS22775"
                     /old_locus_tag="PVK74_22775"
     CDS             complement(6434..6904)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359035"
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473525.1"
                     /locus_tag="PVK74_RS22775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22775"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_113972218.1"
                     /transl_table=11
                     /translation="MATPDRPGFALPLLLLAGFRTLVDDLHAELARQGHPELRPAHGFV
                     LQAVGPDGTTASDLGQRLGVSKQAAGKTVDRLVALGYLERVDDPADARRKLVRTTAKGR
                     DGLHRSAAVFDELRDRWAATLGADRVAAIEDDLRRMVPADVFRLDVPGWFGG"
     misc_feature    6919..6934
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.98"
                     /tool="antismash"
     gene            6968..7522
                     /db_xref="GeneID:91359036"
                     /locus_tag="PVK74_RS22780"
                     /old_locus_tag="PVK74_22780"
     CDS             6968..7522
                     /GO_function="GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283550.1"
                     /locus_tag="PVK74_RS22780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22780"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_210884429.1"
                     /transl_table=11
                     /translation="MSRFTTYEPDTAPAAARPVMAGVRRSLGHLPAAVGLMAGSPELLK
                     GFLAANAAFEATDLDAVAREVVVLTVATRNGCHLCVAMHTATLVRHAAAPELIEALRTG
                     ATLPDPRLEALRRFTVAVLDHRGAVPDADLDALLAAGWQRRHALDVVLGVGTYTISTFA
                     NRLTEAPLDAPLAAYAWTPAA"
     gene            7616..9076
                     /db_xref="GeneID:91359037"
                     /locus_tag="PVK74_RS22785"
                     /old_locus_tag="PVK74_22785"
     CDS             7616..9076
                     /GO_function="GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019901303.1"
                     /locus_tag="PVK74_RS22785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22785"
                     /product="menaquinone biosynthesis decarboxylase"
                     /protein_id="WP_043327390.1"
                     /transl_table=11
                     /translation="MAARGFPYTDLKDFLAALERAGELRRVSAPVDPTLEISEIVTRTV
                     RAGGPALLFERPTRGEMPVAINLFGTEKRMAMALGVEDLDEIGARIGDMLKPELPQGFS
                     GMMGGLGKVMQLKSMPPKKVKTAPCQQVVYRGDDVDLNRLPGLQVWPGDGGIFHNFGLT
                     HTKHPETGKRNLGLYRLQQHSHNTIGMHWQIHKNSTAHHAVAERLGERLPVAIAIGADP
                     VVAYSASAPLPADIDEYLFAGFLAGERVEMVDCLTVPLQVPAHAQIVLEGYIEPGERLP
                     EGPFGDHTGFYTPVEPFPVMHIECMTMQRDPVYHSIVTSQPPQEDHGLGKATERIFAPL
                     LRFLIPDIVDYDLPAAGVFHNCAIVSIRKRYPKHAQKVMNAIWGAHMMSLTKLIVIVDE
                     DCDVHDYNEVAFRAFGNVDYARDLLLTEGPVDHLDHASYQQFWGGKAGIDATRKLPEEG
                     YTRGWPEEMRMSPEVVSLVDKRWKEYGI"
     gene            9076..9981
                     /db_xref="GeneID:91359038"
                     /gene="mqnP"
                     /locus_tag="PVK74_RS22790"
                     /old_locus_tag="PVK74_22790"
     CDS             9076..9981
                     /codon_start=1
                     /db_xref="GeneID:91359038"
                     /gene="mqnP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787854.1"
                     /locus_tag="PVK74_RS22790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22790"
                     /product="menaquinone biosynthesis prenyltransferase MqnP"
                     /protein_id="WP_043327388.1"
                     /sec_met_domain="ubiA (E-value: 9.2e-93, bitscore: 309.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAVQERPGRVASFLKLVAIEHSVFALPFAYLSALTAMQLNGGR
                     VRWGDLLLITVAMVGARTFAMAANRILDRRIDARNPRTANRELVTGAVSVRTAWTGAAV
                     ALVVFLAAAALLNPLCLVLAPLAVVPLIVYPYGKRFTNWPHAILAVAQAVGPVGAWLAV
                     TGTLDGSGPAWLLGAAVGLWIGGFDLIYACQDSEIDREIGVHSVPARYGRRFALHASTV
                     AHVVTFALFIWFGAWVGFGWLWWIGLALTAAAFAYQHLVVSPTDLSKVNRAFFTANGFV
                     GIALFVLALLDLVIRLGLRP"
     gene            complement(10001..10966)
                     /db_xref="GeneID:91359039"
                     /locus_tag="PVK74_RS22795"
                     /old_locus_tag="PVK74_22795"
     CDS             complement(10001..10966)
                     /codon_start=1
                     /db_xref="GeneID:91359039"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283553.1"
                     /locus_tag="PVK74_RS22795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22795"
                     /product="hypothetical protein"
                     /protein_id="WP_064448406.1"
                     /sec_met_domain="T1TS (E-value: 1.6e-73, bitscore: 247.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAVLRALRSDCPITPRLSPYADDVQGWLVELVDRLGLPPDPAT
                     RRRLARAGFARYAGRLYPDATEADLRVLTALFTWFFLVDDACDGRDGLTPGQIRALRDG
                     ALALLREGPRARHPGFSGPLRRLLVQAWREPRRRMPARWRLRFADAVADHLDGVHREAT
                     ATGSGRPPGVAEYVRLRRATSAAYVSYPLIEFASGRPLPDAVYHHPALRRLADLANDLL
                     SWFNDIASLERDHATGGGHNLVLAVAAERGVPLPAAVDLVAGHWRAEMARFAALRAAAP
                     SFGPTLDDAVAVHLDGLAAAVRGTVDWTLESARYPVTPAS"
     gene            11112..11756
                     /db_xref="GeneID:91359040"
                     /locus_tag="PVK74_RS22800"
                     /old_locus_tag="PVK74_22800"
     CDS             11112..11756
                     /GO_function="GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006725 - cellular aromatic compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359040"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020515109.1"
                     /locus_tag="PVK74_RS22800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22800"
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="WP_030500727.1"
                     /sec_met_domain="Flavoprotein (E-value: 1.1e-21, bitscore:
                     75.6, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREPWVVGVSGASGTPYAAAVVRALLDAGQAVDLIVSRAARLTVL
                     DETGRPFRDGHWAEDLAAWLDRDLTGADIRHWPAGDLAAGPSSGSYRVRGMAVVPASTA
                     ACAGIAIGLSKDLLQRAAEVNLKERRPVVVVPRETPVTRSHLEHLIALHDAGAVVLPAS
                     PGFYGAGAAASAGQLVDFVAGKVLDALGVPHTLFRRWAGELAAGRREPGPA"
     gene            complement(11814..12080)
                     /db_xref="GeneID:91359041"
                     /locus_tag="PVK74_RS22805"
                     /old_locus_tag="PVK74_22805"
     CDS             complement(11814..12080)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473529.1"
                     /locus_tag="PVK74_RS22805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22805"
                     /product="BldC family transcriptional regulator"
                     /protein_id="WP_013473529.1"
                     /transl_table=11
                     /translation="MDTGDRLLTPGEVAALFRVDPKTVTRWAAAGRIGSIRTPGGHRRF
                     RESEVRALLEGEGMLDEAEDMGKARNMGPTASTGPGPANAGMY"
     misc_feature    12169..12189
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.26"
                     /tool="antismash"
     misc_feature    12338..12351
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.03"
                     /tool="antismash"
     gene            12348..12806
                     /db_xref="GeneID:91359042"
                     /locus_tag="PVK74_RS22810"
                     /old_locus_tag="PVK74_22810"
     CDS             12348..12806
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359042"
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012184509.1"
                     /locus_tag="PVK74_RS22810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22810"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_030500728.1"
                     /transl_table=11
                     /translation="MDTIDLSLVELLRGNARLSYAELARQVGLSAPAVHERVGKLESSG
                     VIRAYRAEVEPESIGLGVTALIGIIEDSDADTDDVLEAFRRIPEIESCYFMAGVESFLL
                     KARVGTIAELEQLIVRLNRTAGVASTRTSIALSTKWENRPQPLEPPTA"
     gene            12849..13691
                     /db_xref="GeneID:91359043"
                     /locus_tag="PVK74_RS22815"
                     /old_locus_tag="PVK74_22815"
     CDS             12849..13691
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359043"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473530.1"
                     /locus_tag="PVK74_RS22815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22815"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_274477173.1"
                     /transl_table=11
                     /translation="MTISGRGAAVVTGAAGGLGRAIAVALHADGWNVLLTDVDADAVAT
                     AAAPLGGWSRPLDVRDESACADVAAEAAAAPGGLGLWVNNAGILVTGPSWAHDAPTRRA
                     VVEVNALGAMNGTLAAVAVMREQGRGHVLNVVSLAGLIAAPGETVYAASKHALLAFSLG
                     TLSDLRMAGVRGVHVSCLCPDGIWTPMLHDKLDDPGALASFTGSLLTPERVAARAVRLA
                     RRPRPVVSLPRWRGAQVRLLDAFPRLALALTPVIRATGRAGQRRQARRVRGNPSPPRL"
     gene            13702..14793
                     /db_xref="GeneID:91359044"
                     /locus_tag="PVK74_RS22820"
                     /old_locus_tag="PVK74_22820"
     CDS             13702..14793
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359044"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454521.1"
                     /locus_tag="PVK74_RS22820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22820"
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="WP_274477174.1"
                     /sec_met_domain="PALP (E-value: 2e-46, bitscore: 157.2,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHLDRCDEASRRWVTEAIAAVEADANRSADTHLLPFPLPREWGI
                     DLYLKDESVHPTGSLKHRLARSLFLYGLCNGWIGPDTTIVEASSGSTAVSEAYFARMLG
                     LPFIAVMPASTSPEKIAQIEFQGGRCHLVQDPAKVVVEARWLAEDSGGRFMDQFTYAER
                     ATDWRGNNNIAESIYAQLALERHPVPAWIVVGAGTGGTSATIGRYARYRRLPTKLCVVD
                     PENSAFYPAWQAGDWSVCTGRGSRIEGIGRPTVEASFLPSVVDRMVQVPDAASLAAMRA
                     GSAVLGRRVGGSTGTNLWGAFGLIAQMLADGRTGSVVTLICDPGDRYGDTYYSDEWVAA
                     QGLDLAPHLATIDRFLTDGAWPA"
     gene            complement(14824..15444)
                     /db_xref="GeneID:91359045"
                     /locus_tag="PVK74_RS22825"
                     /old_locus_tag="PVK74_22825"
     CDS             complement(14824..15444)
                     /codon_start=1
                     /db_xref="GeneID:91359045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473532.1"
                     /locus_tag="PVK74_RS22825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22825"
                     /product="putative glycolipid-binding domain-containing
                     protein"
                     /protein_id="WP_210884426.1"
                     /transl_table=11
                     /translation="MPKSLFWARTDTAGCEHVVLDGGQGLTAQGVALAVDPIPYTCRYR
                     LALAPDWSTDQLEVEAEGAGWSRSVRLERGRDGWRVRTGEEGDLDAALSAAGHPPAGLP
                     GTDDPGRLDDALDVDLGGSPLTNTMPIRRIGLGRLPADMATAVTVAWVLLPGLAVIPAE
                     QVYTSLGPGRVRYASGTFTADLEVDPEGFVVRYPGLAERVDPR"
     gene            complement(15520..15729)
                     /db_xref="GeneID:91359046"
                     /locus_tag="PVK74_RS22830"
                     /old_locus_tag="PVK74_22830"
     CDS             complement(15520..15729)
                     /codon_start=1
                     /db_xref="GeneID:91359046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283560.1"
                     /locus_tag="PVK74_RS22830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22830"
                     /product="DNA-binding protein"
                     /protein_id="WP_041798756.1"
                     /transl_table=11
                     /translation="MRRPRLYGPGELAALFGVSRQRVLQITRRPGFPEPLARLIGMNVW
                     DADEVDEWARHNRPPRPTEGDEQG"
     gene            complement(15764..15979)
                     /db_xref="GeneID:91359047"
                     /locus_tag="PVK74_RS22835"
                     /old_locus_tag="PVK74_22835"
     CDS             complement(15764..15979)
                     /codon_start=1
                     /db_xref="GeneID:91359047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787846.1"
                     /locus_tag="PVK74_RS22835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22835"
                     /product="hypothetical protein"
                     /protein_id="WP_036311366.1"
                     /transl_table=11
                     /translation="MTKETGPGELVAAGEILKMLGVGRSRFREIRRHPAFPAPYQELSV
                     GAVWLKRDVERYIREHRPPRPADDDE"
     gene            16167..16418
                     /db_xref="GeneID:91359048"
                     /locus_tag="PVK74_RS22840"
                     /old_locus_tag="PVK74_22840"
     CDS             16167..16418
                     /codon_start=1
                     /db_xref="GeneID:91359048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787844.1"
                     /locus_tag="PVK74_RS22840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22840"
                     /product="flavin reductase"
                     /protein_id="WP_174536643.1"
                     /transl_table=11
                     /translation="MTQRHAPLKPLWVCTADLLNWPCENAKVELVADYRHDRRNLAVDL
                     AALMRQATDDLAGLYSEPPDPAEMHIRFMGWLRSVRDV"
     gene            complement(16712..18613)
                     /db_xref="GeneID:91359049"
                     /locus_tag="PVK74_RS22845"
                     /old_locus_tag="PVK74_22845"
     CDS             complement(16712..18613)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91359049"
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283563.1"
                     /locus_tag="PVK74_RS22845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22845"
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_274477175.1"
                     /transl_table=11
                     /translation="MTTFAESSTSPSVDPNSDAVDFASLGLPRQLVEALARQGITTPFE
                     IQRATLPDSLAGRDVLGRGQTGSGKTLAFGLPVIARVADRNRARPLHPRALVLVPTREL
                     AMQVNDALVPLGKSVGVFLKTAVGGVPYDRQIDALRRGVEIVVATPGRLGDLIERGVCR
                     LDDVEITVLDEADQMADMGFLPEVTQLLSKTPADAQRLLFSATLDNDVDTLVKRFMTDP
                     VTHSTAPATAAVSTMDHHLLLIPPHDKFAVAASIAAREGRTMLFARTQLGVDRLVEQLA
                     AVGVRAGGLHGGKTQRMRTKTLAEFREGRTPVLVATDVAARGIHVDGVSLVLHVDPPKD
                     PKDYLHRAGRTARAGESGAVATLVLPKQRRTTLAMMEKAGVEPAETRVRAGDEALAELT
                     GAREPSGVPVRDEPEPRRGGPRRFGDRDGRGFDRGGRGGFSDRGERRFGDRDGRSERRY
                     GDRPTGERSGDRFADRGGDRRFGDRPAGERYSGERAGGGERRFGRPERRDDRSFGDRRS
                     DGRSFGEQRSDDRGQRSDRFGGQRDDRRFGERADRPFGDRHRPAAGRGYDRDERRYDDR
                     PGGFGDRRQEDRPHAERRFGDRGDARPAERRSGGFRAEGRGRDDRRGFGGRPPARTH"
     misc_feature    complement(18610..18619)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.4"
                     /tool="antismash"
     gene            complement(18803..20782)
                     /db_xref="GeneID:91359050"
                     /locus_tag="PVK74_RS22850"
                     /old_locus_tag="PVK74_22850"
     CDS             complement(18803..20782)
                     /codon_start=1
                     /db_xref="GeneID:91359050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473534.1"
                     /locus_tag="PVK74_RS22850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22850"
                     /product="hypothetical protein"
                     /protein_id="WP_274477176.1"
                     /transl_table=11
                     /translation="MGEHEVPAEKVHPGPTPDAADPADDSPAAARPGPVAVARARVTVA
                     GAAVPPPAGDEPPAAPSSPTTYRAGTPADAPPLDRRQPGATVPPSTWSAFAVAERPATP
                     EAPISTPAAGTPSPATPDGPAAGIPAPRVSGSARVPVPTPTALADSAAPAVPPAVSAPA
                     VSAPADSSTPAAPAGVSTPAGASTSAGGETPGEDATGADAVATDDRPNRDAAPGGPENA
                     AGSTATDPRDGAPAAGSADSGTASPALAEQPAGPGAVPSAKPADLDAAPSAKPAGLNAA
                     LSAKPAGQGGTAHARASAAVPGLSRVSADEIAASVVAAPAAATVYRAGPVNPEPPEPAQ
                     PPEPAQPPAPHGPEPEPAPTPVPGPTPPSPAPPVPEPEPPFRPTPPAPAPPAPAPTPPG
                     PVPPVPGPPVPPPGPAVPPPPPPPGPMPAPPFPPPPAMTATANPLPAPLFPAPPATAGP
                     SFGTPSATPGAPSFVTPPVTAGPPSFATPSAGSAVPPAPATTPFPSAPPATTGTPASSA
                     ESPPAWAAAPVSAPPPPAVPAPALPTWPPPATPARDADATRPVRQQSGSTDLAGAVYGG
                     GTDGPGFATVSFPQGNPLENSGSLTGHILAQGWSEESPAARGGNAKVIIVLAVALTMLI
                     AISLLVVFLANDALSGLTGAMPVE"
ORIGIN
        1 ggtccgctgt acggcgatgg acagttcggc acgatccacc cggtcagcct atcgcgatct
       61 cgaccgacgg gcctgtcgag cggatcgctg gcggcctgcc gccgctcacc ggggtgagcc
      121 tggtaacccc cgtcgcgggg tgcgtgccag gcagtgctcc ggcgctgaca caatgggccc
      181 atcgtgaccg agacgctttc cgccggatcc ggccgctacc cggccgacgc cccggcctcc
      241 gaggccctgt tcgaccgcgc caaggccgtc gtgcccggcg gggtgaactc tcccgtgcgc
      301 gcgttccgtg ccgtcggcgg caccccgcgc ttcatggtcc ggggggaggg tccgtggctc
      361 ttcgacgccg acggtcgtcg gtacgtcgac ctggtctgct cctggggccc gctcattctc
      421 ggccacgcgc acccggcagt ggtggaggcg ctgcgcgagg ccgccacgct gggcacgagc
      481 ttcggcacgc ccaccccggg tgaggtggac ctcgccgagg agatcatcgc gcggacgccg
      541 gtcgagcagg tgcgcctggt caactccggc accgaggcga ccatgtcggc gatccggctg
      601 gcccgcggct tcaccggccg ctccaaaatc atcaagttcg ccggctgcta ccacggccac
      661 tcggacgcgc tgctcgccgc cgccggctcc ggcgtggcca cgttcggcct gcccgactcg
      721 cccggcgtga ccggcgcggc ggcgagcgac acgatcgtgc tgccgtacaa cgacctgcgc
      781 gcggtcgagg aggcgttcgc cgcccagggc cagcacatcg ccgcgatcat caccgaggcc
      841 gccgccggca acatgggcgt gatcgccccg cgtgacggct tcaacgccga actggcccgg
      901 atcgcgcacg cgcacggcgc gctgctcatc gtcgacgagg tgatgaccgg gttccgggtg
      961 tcccgcgccg gatggcacgg cctcgacccg tcggacgcgg acctgtggac gtacgggaag
     1021 gtcatgggtg gcggcctgcc cgccgcggcg ttcggcgggc gcgcggagat catggcgaag
     1081 ctcgccccgg ccggcccggt ctaccaggcc gggacgctct ccggtaaccc gctggcctgc
     1141 gccgccggac tggccacgct gcggctggcc gacgacgcgc tctaccggcg gctcgacgag
     1201 acctccgccg cgctcggcaa gctcaccacc gaggcgctgt ccgcggccgg cgtgccgcac
     1261 cgcctctcca ccgccggcaa catgttctcg gtcttcttca ccgacgcgga cgtgcgcgac
     1321 tacgacagcg cccgtaccca ggtggtgccg gcgttcaagg cgttcttcca cgcgatgctc
     1381 gccggtggcg tctacctgcc gccgagcgcg ttcgagtcgt ggttcgtctc gaccgcgatc
     1441 gacgacgcgg cgtgggagca gatcgccgcc gccctgccgg tggcggcgcg ggcggcggca
     1501 gcggcgggaa gcggggggta actatggcgg agaccgtggt gcacgtgctg cggcacggtg
     1561 aggtgcacaa cccggacggc atcctctacg gccgcctgcc cgggttccgc ctctccgagc
     1621 tgggcgtgca gatggcgaag gcggccgcgc aggcgctcgc cgaccggacc gtggtgcacg
     1681 tggtggccag cccgctggag cgcgcccagc agaccgccga gccgatcgcg gcgcagttcg
     1741 gcctctccgt cggcgtcgac gagcggctga tcgagagcgc gaactggttc gagggcaaga
     1801 aggtctcgcc cggtgacggc tcgttccgcg acccgcgcaa ctggtgggtg ctgcgcgacc
     1861 cggtgacccc gtcctggggc gaggcgtacc gggccatcgc cgagcgcatg ttcgccgcgc
     1921 tgcacgccgc ccgcgtcgcc gccgagggcc gcgaggcggt gctcgtgtcg caccagctcc
     1981 cgatctggac gctgcgccgg cacgtcgagc gcaagcgcct ctggcacgac ccgcgccgcc
     2041 gccagtgcgg cctggccagc ctcacctcgt tccacttcga cggcgccaag atcgtcggca
     2101 tcgggtactc cgagccggcc gcccacctgg tgtcgatctc gccgaccgcc cggacggcca
     2161 agggggcctg atgctcaccc ggaggctcgc cgccgccctg ctcgccgccg tcaccgccgg
     2221 tacggcgctg gtcggctgct cctccggcaa ccaggagagc cggtgcgcgg ccgacggctc
     2281 cgtcgtcacc tgcgcacccg accagcgctc gaagacgccg aaggtcagcg gtgagctgct
     2341 caccggcggc ggctacgaca tctcccgcga ccgcggccag gtcgtcgtgg tcaacttctg
     2401 gggctcctgg tgcgcgccct gccgcgccga ggccgacgac ctggaggaca cctaccaggc
     2461 cacaaagggc tccggcgtga cgttcctcgg catcaacgtg caggacagca aggacaaggc
     2521 gctcgccttc gaggagggcc gggtcacgta cccgagcatc ttcgacccgg ccagccggca
     2581 ggcgctcaac ttcgacatcc cgccgaacac caccccggcc accgtcgtgc tcgaccgcga
     2641 gggccggatc gccgtggtga tccgccgggc cgtcacccgc gacgagctgc gaccgatcgt
     2701 cgagaagatc gccgccgagt cgccggcgcc gaacggcgcc cgctgatggg cgagacgttc
     2761 cgccagctcg ccgagtccgg cccgctgctg ttcgcggtgg gcgcggccgc actggccggg
     2821 ctggtgagtt tcctgtcccc gtgcgtgctc ccgctgatgc ccggctacct gtcgtacgtg
     2881 accggcctgg ccggcgccga cctggagggt gcaaggaagg gccccctgtt aacgcctccg
     2941 gtagaggaag ggccccttgt taacagcggc ggcgcgagcg ggggcggtgt gggcgtcgcc
     3001 gagcgggcgg cgccggcccg gaccaccgcg gccgtcaagg gccgggtgct cgccggcacg
     3061 ctgctgttca tcgccggctt cacagtcgtg ttcgtcgcca ccgcgatcct cttctccggc
     3121 gtcggcaagc tcttcttccg gtacgagcgc acgctggaga tcgtcatcgg cgcgctcgtg
     3181 gtggtgctcg ggctcggcta cctcggggtg atccccggca tgcagcggga gttccgcatc
     3241 cgctggctgc cctccgccgg gctgctcggc gcgccggtgc tcggcgcggt cttcgcgctc
     3301 agctggctgc cctgcaccgg cccgacgctc ggcgcggtgc tcggcatggc ggccaccgag
     3361 gggggcaccg accgggccgt ggtgctcgcc gtggcgtact gcctcgggct ggggataccg
     3421 ttcgtcgtct tcgggctggg cttccagcgc ctgctcgggg tgttccgcgc cgtccggcgc
     3481 aacagccgct gggtcacccg catcggcggg gccctgctga tcgcgatcgg cctggcgctg
     3541 atcagcggcg gctgggtgaa cgtggtgatc tggctgcaga cgaacgtggg cgtgggcgag
     3601 gtgagcatct gatgacgacc gtcgacgacc ggccgtcgac ccctccggcg caggcacccc
     3661 gacggcgggt caacccggtg ctggccctgc tgcgcaactc gtggcggcag ctcaccagca
     3721 tgcgtaccgc gctgatcctg ctgttcctgc tcgccgtcgc ggccatcccc ggctcggtgc
     3781 tgccgcagcg cggcgtcaac ccggagcggg tcaaccagtg gttcgtggac caccccgatc
     3841 tcgcaccccg gctggaccag atcggcgcgt tcgaggtctt cggctcggtc tggttctccg
     3901 cgatctacct gctgctgttc acctcgctga tcggctgcat cctgccccgc gcccgggacc
     3961 acgtccgcgc gctgcggatg aagccgccgg ccgcgccgaa gcggctcgaa cggctgcccc
     4021 agcacacggt gctggaggcc ccggccgccg ccgaccccga ggcgatcgcg gcggtgctgc
     4081 gcggccgccg gtggcgggtc accgtgcgcg gcaacgaggt ctccgccgag aagggctacc
     4141 tcaaggagac cggcaacctg ctcttccacg tgtcgctggt cgccgtcctg ctcggggtcg
     4201 cgctcggttc ctggtacgga tggcacggca accgcatcct ggtcgcgggc gaggacaacg
     4261 ccttctgcaa cacccgtcag cagtacgccg aggcgtcgct cggcccgcgc gtggacagcg
     4321 ccgacctgcc gccgttctgc ctgacgctgg agaagttcga ggccgactac ctgccgtccg
     4381 ggctggcgtc ccgctactgg gccacggtga ccgtggacga gccgggcggc acggcgcgga
     4441 ccgccggctt ctcggtcaac tcgccgctgc ggctcggctc ggcgaacgtc tacctgctcg
     4501 gcaacggcta cgcgccgctg ctgaagtaca ccgacaagta cggccgcagc cagaccagcg
     4561 aggcgccgtt cctgcgtacc ggcgactcca acgcgaccga ggagggcgtg gcgatcttcc
     4621 cggacgccaa cgtcgacccg aagaccggcg cgcggtcccc ggaccagcag atcgccttcg
     4681 acgggctcta cctgcccacc gggccggaga gcgcgccgta cgtggcgtcg cagtacccgg
     4741 ccgagcgcaa cccgatggtg aacctgaccg cgtaccgcgg gaacctcggg atggacgccg
     4801 gcatccccgg ctcggtctac gcgctggacc ggcggcagat cgacgacggc aagctcaagg
     4861 agatcggcac caagctgctg cggccggggg agaagtggac cctcgacgac ggcagcacgc
     4921 tggagttcgt cggcaccaag ccgtacatca cgctcgcggt ccggcacgcg cccgggcaga
     4981 cgctgctgct ggtggccagc ggcacgctgc tgctgggcct gatgggctcg ctgttcgccc
     5041 ggcggcgccg ggtgtggttc cgggtttcgc ccccggaggg tgtatctccg acgggcggta
     5101 gtagtttggt ggaggccggt gggctgccgc gcaccgagca cccagggttc gccgacgagt
     5161 tcgcgcagct cgtcgccgcg gtgagcggcg acgcgccgga cgcgcggcgg gcgcgagaag
     5221 gagacgagtg atgtccgcac tctccgacca gctggtcgcg tacgcgatcc tggtgtacct
     5281 gatcgcgatg atcagccacg ccgtggagtt cgcgctgggc aacgcgcgga aggtccccgc
     5341 ggccgcgccc gcgcgggaac tggtcggcgc gggcgtcggc ggcgccggcg gcaccgtcga
     5401 cgagccggcc gcgccgccgc gcccggacca ctccgccgcc cgggccgtgc tggccggccg
     5461 gatcgccggc tggctcaccg cggtcgccgc cgccgtgcac ctgggcgcgg tgatcacgcg
     5521 gggcgtcgcc gccgaccgga tgccctgggg caacatgtac gagttcgtgc tgaccggcac
     5581 ctggatcggt gtggcggcct ggctcgtggt gctctggaag cagccgtggc tgcgccggct
     5641 cgggctgttc ctgacgctgg tgatggtgct gctgctggcg ttcgccgagc tgaagctcta
     5701 cgtgccgatc gagccgctga tgccggcgct gcagtcgtgg tggttcatca tccacgtctc
     5761 gacgatcatc tttgcctcgg gcctcttcct gctgggcgtg gtgcccgccg ccgcgtacct
     5821 gatgcgggcc ggctgggagc agggtcgccg cagcttcccg tacaccctgg cccgccgcct
     5881 tccggcggcg gccgggctgg agcggttgac cttcacgctg cacgccttct cgttcccgat
     5941 cttcacgttc gcggtgatcg cgggcgcgat ctgggccgag gcggcctggg gccgcgcctg
     6001 gggctgggac cccaaggaga cctgggcgtt catctcctgg gtggtgtacg cgggctacct
     6061 gcacgcccgg gccacgccga gcgtgaagcg caacgtggcc acctggatct ccatcgtggg
     6121 cttcctgacc gtgatgatga acctgttcgg cgtgaacttc ttcttcaccg gtctgcactc
     6181 gtacgccggg gtgtagtggc cgggcgcgcg ctcagcacct cgtccacccg gcgcgtgacc
     6241 tggtaggcca cctccggcag gtcggccagt tcgaggcggt cggcccggag cgcgaactgg
     6301 gcgtgcagtt cgcgggccac cgcgtcgcgg atctctgcct ggagtgggct gaggccgtcc
     6361 gggtcaccca ccacgtatgc gtcgtccatc cgtcgatgat gaaccgccgt cggcgaacct
     6421 gtcagtgacg aattcatccg ccgaaccagc cggggacgtc gaggcggaac acgtcggcgg
     6481 gaaccatccg gcgcaggtcg tcctcgatgg cggcgacccg gtccgcgccg agcgtggccg
     6541 cccagcggtc gcgtagctcg tcgaagaccg ccgccgagcg gtgcagcccg tcgcggccct
     6601 tcgcggtcgt ccggaccagc ttgcgtcggg cgtcggcggg gtcgtccacg cgttccaggt
     6661 agccgagcgc gaccagccgg tccaccgtct tgccggcggc ctgcttggag acgccgaggc
     6721 gctggccgag gtcggaggcg gtggtgccgt ccgggcctac ggcctggagg acgaacccgt
     6781 gggccgggcg cagctcgggg tgcccctggc gggccagctc ggcgtgcagg tcgtcaacga
     6841 gcgtacggaa gccggcgagc aggagcagcg gcagcgcgaa gccggggcgg tcaggcgttg
     6901 ccacgttcga caaccacgtt tactatttcg tcaaccacgt tgaccatctt acgagagggg
     6961 cacagtcatg tcccgcttca ccacgtacga gccggacacc gcacccgccg ccgcccgccc
     7021 ggtcatggcc ggggtacgcc gctcgctggg ccacctgccc gctgccgtcg gcctgatggc
     7081 gggctcaccc gaactattga agggcttcct cgccgccaac gccgcgttcg aggcgaccga
     7141 cctcgacgcg gtcgcccggg aggtggtcgt gctcaccgtc gccacccgca acggctgcca
     7201 cctctgcgtg gccatgcaca ccgctacgct cgtccggcac gccgccgcgc cggagctgat
     7261 cgaggcgctg cggaccggcg cgacgctgcc cgacccccgg ctggaggcgc tgcgccggtt
     7321 caccgtcgcc gtcctcgacc accggggcgc ggtccccgac gccgacctcg acgcgctgct
     7381 cgccgccggg tggcagcgcc ggcacgcgct ggacgtggtg ctcggcgtcg gcacgtacac
     7441 catctccacg ttcgccaacc ggctcaccga ggcgccgctc gacgcgccgc tggccgcgta
     7501 cgcctggacg cccgcggcct gagctgcggg gtgttaagaa ggggcccgtc ctctaccgga
     7561 ggcgttaaca gggggccctt ccttacctcg caggaacgtg cgggaggatg gcggcatggc
     7621 ggctcgtggc ttcccgtaca ccgatctcaa ggacttcctc gcggcgctgg agcgcgcggg
     7681 cgagctgcgg cgggtgagcg cgccggtcga ccccacgctg gagatcagcg agatcgtcac
     7741 ccgcaccgtc cgggccggcg ggccggcgct gctgttcgag cgccccaccc ggggcgagat
     7801 gccggtggcg atcaacctgt tcggcaccga gaagcggatg gcgatggcgc tcggggtgga
     7861 agacctcgac gagatcggcg cgcggatcgg cgacatgctc aagccggagc tgccgcaggg
     7921 cttctccggg atgatgggtg gcctcggcaa ggtcatgcag ctcaagtcga tgccgccgaa
     7981 gaaggtcaag accgccccct gccagcaggt cgtctaccgg ggcgacgacg tcgacctgaa
     8041 ccggctgccc gggttgcagg tgtggcccgg cgacggcggg atcttccaca acttcgggct
     8101 gacccacacc aagcacccgg agaccggcaa gcgcaacctc gggctctacc ggctccagca
     8161 gcacagccac aacacgatcg gcatgcactg gcagatccac aagaactcca ccgcgcacca
     8221 cgcggtcgcg gagcggctgg gcgagcggtt gccggtggcg atcgccatcg gcgcggaccc
     8281 ggtggtggcg tactcggcca gcgcgccgct gcccgccgac atcgacgagt acctgttcgc
     8341 cgggttcctc gccggtgagc gggtcgagat ggtcgactgc ctgaccgtcc cgctccaggt
     8401 gccggcgcac gcgcagatcg tgctggaggg ctacatcgag ccgggcgagc ggctgcccga
     8461 gggcccgttc ggcgaccaca ccggcttcta cacgccggtc gagccgttcc cggtgatgca
     8521 catcgagtgc atgaccatgc agcgcgaccc ggtctaccac tcgatcgtca cgtcccagcc
     8581 gccgcaggag gaccacggtc tcggcaaggc caccgagcgg atcttcgcgc cgctgctgcg
     8641 cttcctgatc ccggacatcg tcgactacga cctgcccgcc gccggtgtct tccacaactg
     8701 cgcgatcgtg tcgatccgca agcgctaccc gaagcacgcg cagaaggtga tgaacgcgat
     8761 ctggggcgcg cacatgatgt cgctgaccaa gctgatcgtg atcgtggacg aggactgcga
     8821 cgtccacgac tacaacgagg tcgcgttccg cgccttcggc aatgtcgact acgcccggga
     8881 cctgttgctc accgaaggcc cggtggacca tctcgaccac gcctcgtacc agcagttctg
     8941 gggcggcaag gcgggcatcg acgcgacccg caaactgccc gaggagggct acacccgggg
     9001 ttggccggag gagatgcgga tgtcgcccga ggtggtctca ctggtggaca agcgctggaa
     9061 ggaatacggg atctgatgac ggcggcggta caggaacggc ccggccgggt cgcgtccttc
     9121 ctcaagctcg tcgccatcga gcactcggtc ttcgcgctgc cgttcgcgta cctgtcggcg
     9181 ctgaccgcca tgcagctcaa cggcggccgg gtgcgctggg gcgacctgct gctgatcacc
     9241 gtggcgatgg tcggcgcgcg gacgttcgcc atggccgcga accgcatcct cgaccggcgg
     9301 atcgacgcgc ggaacccgcg tacggcgaac cgggaactgg tcaccggcgc ggtgagcgtg
     9361 cggacggcct ggaccggcgc ggccgtcgcg ctcgtggtgt tcctggccgc cgccgccctg
     9421 ctcaacccgc tctgcctggt gctcgcgccg ctggccgtgg tgccgctgat cgtctacccg
     9481 tacggcaagc ggttcaccaa ctggccgcac gccatcctcg cggtggcgca ggcggtcggc
     9541 ccggtcggcg cctggctggc ggtcaccggc acgctcgacg gctccggccc ggcctggctg
     9601 ctcggcgcgg cggtcggcct ctggatcggc ggcttcgacc tgatctacgc ctgccaggac
     9661 tcggagatcg accgggagat cggcgtgcac agcgtccccg cccggtacgg ccggcgcttc
     9721 gcgctgcacg cctccaccgt cgcgcacgtg gtgacgttcg cgctgttcat ctggttcggc
     9781 gcgtgggtcg gcttcggctg gctgtggtgg atcgggctgg cgctgaccgc tgccgccttc
     9841 gcgtaccagc acctggtggt cagcccgacc gacctgagca aggtcaaccg ggcgttcttc
     9901 accgcgaacg gcttcgtcgg catcgcgttg ttcgtcctcg cgctgctcga cctggtgatc
     9961 cggctcggcc tgcggccgta acggcaacgc cggaacgcgg tcaggacgcc ggggtgaccg
    10021 gatagcgggc gctctccagc gtccagtcca cggtgccgcg cacggcggcg gccaggccgt
    10081 cgaggtggac ggcgacggcg tcgtcgagcg tcgggccgaa cgacggcgcc gccgcgcgga
    10141 gcgccgcgaa ccgggccatc tcggcccgcc agtgcccggc caccaggtcg accgccgccg
    10201 gcagcggcac gccccgctcg gcggccaccg ccagcaccag gttgtgcccg ccgccggtgg
    10261 cgtggtcgcg ctccagcgag gcgatgtcgt tgaaccagga cagcaggtcg ttcgcgaggt
    10321 ccgcgagccg ccgcagtgcc gggtggtggt agaccgcgtc gggcagcggg cgtccggacg
    10381 cgaactcgat gagcgggtac gacacgtacg ccgccgaggt ggcccggcgc agccgcacgt
    10441 actcggcgac gcccggcgga cggcccgacc cggtggcggt ggcctcccgg tggacgccgt
    10501 cgaggtggtc ggcgaccgcg tcggcgaaac gtagccgcca gcgggccggc atccggcggc
    10561 ggggctcccg ccacgcctgc accagcaggc gccgcagcgg gccggagaag cccggatggc
    10621 gggctcgcgg accctcgcgc agcaacgcga gcgcgccgtc gcgcaacgcg cggatctgcc
    10681 ccggcgtcag cccgtcccgc ccgtcgcagg cgtcgtcgac caggaagaac caggtgaaca
    10741 gcgcggtcag cacccgcagg tccgcctcgg tggcgtccgg gtagaggcgg ccggcgtacc
    10801 gggcgaaccc ggcccgcgcc agccgccgcc gggtggccgg gtcgggcggc agaccgagcc
    10861 ggtcgaccag ttccaccagc cagccctgca cgtcgtccgc gtacggggag aggcggggcg
    10921 tgatggggca gtcggagcgc agcgcccgca gcaccgccgc agtcatcacc ggcccttccc
    10981 acggaagtgg atttgccgat cgaagaattt cacgccgagg gaactcccgt gaaccctctg
    11041 gacatcccgg gcgggccgcc cgaacggggg tcgtggtccg ccgcccgcgg cgaccaggca
    11101 cgcttgaggg catgcgcgaa ccatgggtgg tgggtgtctc cggcgcctcg ggcacgccgt
    11161 acgcggcggc ggtcgtccgg gcactgctcg acgcgggcca ggcggtggac ctgatcgtgt
    11221 cccgggcggc ccggctgacg gtgctggacg agaccggccg gcccttccgg gacgggcact
    11281 gggccgagga cctggccgcc tggctcgacc gcgacctcac cggcgcggac atccggcact
    11341 ggcccgccgg tgacctggcc gccggcccga gcagcggctc ctatcgggta cgcgggatgg
    11401 cggtggtgcc ggccagcacc gccgcctgcg ccggcatcgc catcgggctc tccaaggacc
    11461 tgctccagcg tgccgccgag gtgaacctca aggagcgccg cccggtagtg gtggtgcccc
    11521 gggagacccc ggtgacccgc agccacctgg agcacctcat cgcgctgcac gacgccggag
    11581 ccgtggtgct gccggccagc ccgggcttct acggcgccgg ggcggcggcc tccgccgggc
    11641 agctcgtgga cttcgtggcc ggcaaggtgc tggacgcgct gggcgtcccg cacacgctgt
    11701 tccggcggtg ggccggcgag ctggccgccg gtcgccggga gcccggcccg gcctgaccgg
    11761 acccggcgta cgacgagcgg ggcgcggcct cgatcggacc gcgccccgca cgttcagtac
    11821 atgccggcgt tcgccgggcc ggggccggtg gaagcggtcg ggcccatgtt gcgggccttg
    11881 cccatgtcct ccgcctcgtc cagcatgccc tccccctcga gcagggcccg cacctcggat
    11941 tcccgaaacc ggcggtgccc tcctggagtc cggatactgc cgatccggcc ggccgctgcc
    12001 catctggtca cggttttcgg gtcaacccga aacagcgcag cgacctcacc cggtgtcagc
    12061 aggcgatctc cagtgtccac agccccctcc tcgcgtcgac gaagcccccg gctgaacaca
    12121 ctgcccccgg ccggtgcgag cccagagccg tcatgaggga cgtatggcaa ttacagcacc
    12181 ggctaccgga cgtgtccgcc aaacgcgaaa aacgcacaca ctgggaagtt aggaaatggt
    12241 accggcggag aacccccgtg agcgcacgtt tgtgataggc gcggcccgac ctcatcgtcg
    12301 cccggtggcc gcagtgccgg gccccgatcg agatagggtc actctccgtg gacacgatcg
    12361 acctgagcct tgtggagctg ttgcgaggca acgcccgtct gtcgtacgcc gagctggccc
    12421 gtcaggtcgg cctctccgcc ccggccgtgc acgagcgggt cggcaagctg gagtccagcg
    12481 gcgtgatccg tgcgtaccgg gccgaggtcg agccggagtc gatcgggctc ggcgtcaccg
    12541 cgctcatcgg catcatcgag gactccgacg cggacaccga cgacgtgctg gaggcgttcc
    12601 ggcgcatccc cgagatcgag tcctgctact tcatggccgg cgtcgagtcc ttcctgctca
    12661 aggcgcgggt cggcacgatc gccgagctgg agcagctgat cgtccggctg aaccggacgg
    12721 ccggcgtggc atccacccgt accagcatcg ccctgtcgac caagtgggag aaccgcccgc
    12781 agccgctgga accgcccacc gcctgatcac tctggccccg gcgcggggat tggggttacc
    12841 gtgcgccgat gacgatctcg ggacgcggcg ccgcagtggt caccggtgcg gccggcgggc
    12901 tgggccgggc catcgccgtc gcgctgcacg ccgacggctg gaacgtgctg ctcaccgacg
    12961 tcgacgccga tgccgtggcg accgccgccg cgccgctggg tggctggtcg cgcccgctcg
    13021 acgtacgcga cgaatccgcc tgcgcggacg tggccgccga ggcggcggcc gcacccggcg
    13081 gcctcgggct ctgggtgaac aacgcgggca tcctggtcac cggcccgtcc tgggcgcacg
    13141 acgccccgac ccggcgcgcg gtggtcgagg tgaacgcgct cggcgcgatg aacggcacgc
    13201 tcgccgccgt cgcggtgatg cgcgagcagg gccgcggcca cgtactgaac gtcgtctcgc
    13261 tggccgggct gatcgccgcg cccggcgaga cggtgtacgc ggccagcaag cacgccctgc
    13321 tcgcgttcag cctcggcacg ctgagcgacc tgcggatggc cggcgtccgg ggcgtacacg
    13381 tgtcgtgcct gtgcccggac gggatctgga cgccgatgct gcacgacaag ctggacgacc
    13441 cgggcgcgct ggcatccttc accggttcgc tgctgacgcc ggagcgggtg gccgcgcggg
    13501 ccgtccggct ggcccggcgg ccccggccgg tggtcagcct gccgcgctgg cgcggcgccc
    13561 aggtacggct gctcgacgcc ttcccccggc tcgccctggc ccttacgccg gtgatccggg
    13621 ccaccggccg ggccggtcaa cggcggcagg cccgccgggt ccggggaaac ccgagcccac
    13681 ctcgcttgta acgttgccga cgtgactcat ctcgaccggt gcgacgaggc cagccggcgc
    13741 tgggtgaccg aggcgatcgc cgctgtcgag gcggacgcca accgctccgc cgacacccac
    13801 ctgctgccgt tcccgctgcc ccgcgagtgg gggatcgacc tctacctcaa ggacgagtcg
    13861 gtgcacccca ccggctcgct caagcaccgg ctcgcccgct cgctgttcct ctacgggctc
    13921 tgcaacggct ggatcggccc ggacaccacg atcgtcgagg cgtcgtccgg ctcgacggcg
    13981 gtctccgagg cgtacttcgc gcggatgctc gggctgccgt tcatcgcggt catgcccgcc
    14041 tccacctcgc cggagaagat cgcccagatc gagttccagg gcgggcgctg ccacctcgtc
    14101 caggacccgg cgaaggtggt ggtggaggcg cgctggctcg ccgaggacag cggcggccgg
    14161 ttcatggacc agttcacgta cgccgagcgg gccaccgact ggcggggcaa caacaacatc
    14221 gccgagtcga tctacgccca gctcgcgctg gaacggcacc cggtgcccgc ctggatcgtc
    14281 gtcggcgccg gcaccggcgg caccagcgcc accatcggcc gctacgcccg ctaccggcgg
    14341 ctgcccacca agctctgcgt ggtggacccg gagaactccg cgttctaccc cgcctggcag
    14401 gccggcgact ggtcggtgtg caccggccgc ggctcccgga tcgaaggcat cgggcggccc
    14461 accgtcgagg cgtccttcct gcccagcgtg gtggaccgga tggtgcaggt gccggacgcc
    14521 gcgtcgctcg ccgccatgcg ggccggctcg gcggtgctcg gccgccgcgt gggcggctcc
    14581 accggcacca acctgtgggg cgcgttcggg ctgatcgccc agatgctggc ggacggacgt
    14641 accggctcgg tggtcacgct catctgcgac ccgggcgacc ggtacggcga cacctactac
    14701 tccgacgagt gggtggccgc gcagggcctc gacctcgccc cgcacctggc caccatcgac
    14761 cggttcctga ccgacggcgc ctggccggcc tgaccggcgc cccggctttg gcggcggcgg
    14821 acgtcagcgc gggtcgaccc gctcggccag ccccggatag cgcaccacga aaccctccgg
    14881 gtcgacctcc aggtcggccg tgaacgtgcc gctggcgtac cggacccggc ccgggccgag
    14941 cgaggtgtag acctgctcgg ccgggatcac ggccaggccg ggcagcagca cccaggccac
    15001 ggtcaccgcc gtcgccatgt cggcgggcag ccgccccaac ccgatccggc ggatcggcat
    15061 cgtgttcgtc agcggggacc cgcccaggtc gacgtcgagc gcgtcgtcca gccgacccgg
    15121 gtcgtcggtg cccggcaacc ccgccggtgg gtggcccgcc gcgctcagcg ccgcgtccag
    15181 gtcaccctcc tcgccggtac gcacgcgcca cccgtcccgg ccccgttcca ggcgtacgct
    15241 ccgcgaccag cccgcgccct ctgcctcgac ctccagctgg tcggtcgacc agtcgggcgc
    15301 gagcgccagg cggtaacggc aggtgtacgg gatcgggtcc acggcgagtg ccacgccctg
    15361 cgcggtcagc ccctgcccgc cgtcgagcac gacgtgctcg cagccggcgg tgtcggtccg
    15421 ggcccagaag agcgacttcg gcatggtccg gacgttacgc gacccggccg tcggcggcag
    15481 cggatgcgcg aacgccgccg ccggccggat ggccactgac tacccctgct cgtcgccctc
    15541 agtagggcgc ggcggccggt tgtggcgggc ccactcgtcg acctcgtccg cgtcccagac
    15601 gttcatgccg atcagccggg cgagcggctc ggggaacccg gggcggcggg tgatctgcag
    15661 gacccgctga cgcgatacgc cgaacagggc ggccaactcg ccgggcccgt acaggcgtgg
    15721 tcgtctcacc cgacgaaggt agtcatggtc gtgcctcttc gggctactcg tcgtcgtccg
    15781 ccggccgggg cggccggtgc tcccggatgt accgctccac gtcccgcttc agccagacgg
    15841 cgccgaccga cagctcttga tacggcgcgg ggaatgcggg atgccgccgg atctcgcgga
    15901 atctcgatct gcccacgccg agcattttca agatctcacc ggccgcgacg agttcgcccg
    15961 gtcccgtctc cttggtcacg acttcgaagg taggagcggg ctgacccgac tatcttgacg
    16021 cgaacaagaa atcgcaccta cgtgggcccg tcaacattga caggggggca agggagcgat
    16081 ctgatggatc aggccccccg cccggtggcg agttcgcggc ggacgggggt gccacctgga
    16141 agccgaccca cggcaggagg ccccgagtga cccagcgcca cgctccgctg aaaccccttt
    16201 gggtctgcac ggcagacctg ctcaactggc cgtgcgaaaa cgcaaaggtc gagttggtcg
    16261 ctgactacag gcacgaccgg cgtaacctcg ccgtcgatct ggccgccctc atgcggcagg
    16321 cgaccgatga cctggccggg ctctactccg agccgccgga tcccgccgag atgcacattc
    16381 gattcatggg ctggctgcgg tcggtgcgcg atgtctgacc cgatcggcac cggtctgctg
    16441 ttgtccgccg tcatcgccca ggcgttcggc tgctgggtgg cctggtcgtg gggccggtcc
    16501 gctcggcgaa gtctccggca gaccatcgat cagaccatcc cgacaccgcc gcccgactgg
    16561 cagcctcggc atcgcctgtc gatgttgaac gagccgaccc ggcggtatcc cgtcctcgca
    16621 ccgcgcagct agaacgccac cggcccgttg acccgcagac gcacagccgc cgccgagcgg
    16681 gtgctcggcg gcggctgtgg ctgcgctcag atcagtgggt acgcgccggc ggtcgcccgc
    16741 cgaagccgcg ccggtcgtcc cggccccgcc cctcggcccg gaaaccgcca ctccggcgct
    16801 cggccgggcg cgcgtcgccc cggtcaccga aacgccgctc ggcgtgcggg cggtcctcct
    16861 ggcgacggtc accgaagcca cccggccggt cgtcgtaccg ccgctcgtcg cggtcgtacc
    16921 cgcgcccggc cgccggccgg tgccggtccc cgaacgggcg gtcggcgcgc tcgccgaaac
    16981 gcctgtcgtc gcgctggccg ccgaagcggt cgctgcgctg gccacggtcg tcggaccgct
    17041 gctcgccgaa gctccggccg tcggaccgcc ggtcgccgaa gctccggtcg tcgcgacgct
    17101 ccggccgccc gaagcggcgc tcgccgccac cggcccgctc gcccgagtag cgctcgcccg
    17161 ccggacggtc gccgaaccgg cggtcaccgc cacggtccgc gaaccggtcg ccggaccgct
    17221 cgcccgtggg ccggtcgccg tagcggcgct cgctccggcc gtcgcggtcg ccgaaccggc
    17281 gctcgccacg gtcggagaag ccgccccggc caccccggtc gaagccccgg ccgtcccggt
    17341 cgccgaagcg gcgcgggccg ccgcgccgcg gctccggctc gtcccgcacg ggtacgccgc
    17401 tgggctcgcg cgcgccggtc agctcggcca gtgcctcgtc gcccgcccgg acccgggtct
    17461 cggccggctc gacgcccgcc ttctccatca tggccagcgt ggtgcggcgc tgcttgggca
    17521 gcacgagcgt cgccaccgcg cccgactcgc cggcccgagc cgtgcggccg gcccggtgca
    17581 ggtagtcctt cgggtccttc ggcgggtcca cgtgcagcac cagcgacacg ccgtcgacgt
    17641 ggatgccgcg ggccgccacg tcggtagcga ccagcacggg cgtgcggccc tcgcggaact
    17701 cggcgagcgt cttggtgcgc atccgctggg tcttgccgcc gtgcagccca ccggcccgca
    17761 cgccgacggc cgcgagctgc tcgaccagcc ggtccacgcc gagctgcgta cgggcgaaca
    17821 gcatggtgcg gccctcgcgg gcggcgatgg acgcggcgac cgcgaacttg tcgtgcggcg
    17881 ggatcagcag caggtggtgg tccatggtgg acacggcagc ggtggccggc gcggtcgagt
    17941 gggtgaccgg gtcggtcatg aaccgcttga cgagcgtgtc gacgtcgttg tccagagtgg
    18001 ccgagaacag cagccgctgc gcgtccgccg gggtcttcga cagcagctgg gtgacctcgg
    18061 gcaggaagcc catgtcggcc atctggtcgg cctcgtccag cacggtgatc tcgacgtcgt
    18121 cgagccggca gacgccgcgc tcgatcaggt cgccgagccg gcccggggtg gccacgacga
    18181 tctccacgcc gcggcgcagc gcgtcgatct gccggtcgta cggcacgccg ccgacggcgg
    18241 tcttcaggaa gacgcccacc gacttgccga gcggcacgag ggcgtcgttg acctgcatgg
    18301 cgagttcacg ggtggggacc aggacgagcg cgcgggggtg cagcggccgg gcccggttgc
    18361 ggtcggcgac ccgggcgatc accggcaggc cgaaggcgag cgtcttgccc gagccggtct
    18421 ggccccggcc gagtacgtcg cggcccgcga gcgagtcggg cagggtggcc cgctggatct
    18481 cgaacggggt ggtgatgccc tggcgggcga gcgcctcgac gagctgccgg ggcaggccga
    18541 gcgacgcgaa gtcgacggcg tcggagttcg ggtcgacgga cggggacgtg ctggattcag
    18601 cgaacgtggt caagaaatgc ctctcgagcg gggcgcatct tcgcgatggc ccgccgcggc
    18661 ctgtcacgcc gccgaatcgc ccgcaagatc gcccatgagc gcgcaatcgg ggcgcgccag
    18721 gtcagtaatc ggagacaagt gtacggcgct tcgcccactc cgccacggca gcgcgaggcg
    18781 gtagtgggcg ggctcacccc cgtcactcga ccggcatggc tccggtcagg ccgctgagcg
    18841 cgtcgttggc caggaagacc acgagcagac tgatcgcgat gagcatggtg agcgcgaccg
    18901 ccagcacgat gatcaccttg gcgttgccgc cccgggccgc cgggctctcc tcggaccagc
    18961 cctgggccag gatgtgcccg gtcagcgagc cggagttctc cagcggattg ccctgcggga
    19021 acgacacggt ggcgaaaccg ggtccgtccg tcccgccgcc gtagacggcg ccggcgaggt
    19081 ccgtgctgcc ggactgctga cgtaccggac gggtcgcgtc ggcgtcgcgg gccggcgtgg
    19141 ccggcggcgg ccaggtcggc agcgccggcg ccgggaccgc gggcggcggc ggggcggaga
    19201 cgggcgcggc ggcccacgcc ggaggcgact cggcggagga cgccggagtg ccggtcgtgg
    19261 ccggcggcgc ggacgggaag ggcgtggtgg ccggcgcggg cggcaccgcc gagccggccg
    19321 acggcgtggc gaacgacggc gggcccgcgg tgaccggtgg cgtgacgaac gacggcgcgc
    19381 ctggggtggc cgacggcgtg ccgaacgacg ggcctgcggt ggccggtggc gcggggaaca
    19441 gcggcgcggg caacgggttc gccgtggccg tcatcgccgg tggtggcggg aacggaggcg
    19501 cgggcatcgg acccggtggg ggcggcggcg ggggcaccgc gggtccgggc ggcggcaccg
    19561 gcggccccgg tacgggcgga accggccccg gtggggtggg cgccggcgcg ggcggcgcgg
    19621 gcgcgggcgg cgtgggccgg aacggcggct ccggctccgg caccggcggc gcgggcgacg
    19681 gcggggtcgg acccggtacc ggggtcggcg ccggctcggg ctccggaccg tgcggggccg
    19741 ggggctgcgc gggctccggc ggctgggcgg gctcgggcgg ctccgggttc accggacccg
    19801 cccggtagac ggtcgcggcg gcgggagcgg ccaccaccga ggcggcgatc tcgtcggcgg
    19861 acacccggct caggccgggt accgcggcgc tggcccgggc gtgcgccgtc ccgccttgcc
    19921 cggccggctt cgcggacagc gcggcattga gcccggcggg cttcgcggac ggcgccgcat
    19981 cgaggtcggc gggcttcgcg gagggcaccg cacccggccc ggccggttgc tcggcgaggg
    20041 cgggggacgc ggtgccggag tcggcggacc cggctgccgg ggcgccgtcc cggggatcgg
    20101 tggcggtgct tccggccgcg ttctccggcc cgcccggcgc ggcgtcgcgg ttcggtcgat
    20161 cgtcggtcgc gaccgcatcc gcgccggtgg cgtcctcacc cggcgtctcg ccgcccgccg
    20221 aagtcgacgc gccagccgga gtggacacgc cagccggagc ggccggtgtg gacgagtcgg
    20281 cgggagcgga cacggcggga gcggacacgg caggcggaac ggccggggca gccgagtcgg
    20341 cgagggccgt cggagtgggc acgggcaccc gggcggaacc ggagacacgg ggagccggga
    20401 taccggccgc cgggccgtcc ggcgtggccg gggagggcgt acccgcagcg ggtgtgctga
    20461 tgggggcctc gggcgtcgcc gggcgttcgg ccacggcgaa ggcggaccag gtcgacgggg
    20521 gaactgtcgc gccgggctga cgccggtcca gcggcggggc gtccgccggg gtgcccgcgc
    20581 ggtacgtggt ggggctcgac ggcgccgccg gcggctcgtc gccggcggga ggcggtacgg
    20641 ccgccccggc gacggtcacc cgtgcccgcg cgacggccac cggcccgggg cgggccgctg
    20701 ccgggctgtc gtcggcaggg tcggcggcgt cgggcgtcgg tccggggtgg accttctccg
    20761 ccggaacctc gtgctcgccc atctcgcccc tccgcaccta cgctcgcccc cgaccgtggc
    20821 gccggccgaa agtgcctgga tctcaccgtg ccatattccg gcccgggcgc acagccggag
    20881 tgcgggttgg gtcagtcggc gctgccgctc gcgctggcag aggcgctggc ggaagcgctg
    20941 gcggacgtgc tgcgcgacgg ggcgac
//
