LOCUS       NZ_CP118233            22146 bp    DNA     circular CON 13-JUL-2024
DEFINITION  Micromonospora chalcea strain 1K05785M01 chromosome, complete
            genome.
ACCESSION   NZ_CP118233
VERSION     NZ_CP118233.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora chalcea
  ORGANISM  Micromonospora chalcea
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Study on the Growth Characteristics and Drug Resistance Related
            Proteins of Micromonospora chalcea MCCC 1K05785
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2023) Tianjin University, Tianjin University,
            Weijinlu Nub92, Tianjin, Tianjin 300072, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2022
            Assembly Method                   :: CLC NGS Cell v. 5.29
            Assembly Name                     :: TJU-micro-1.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028768405.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 23:01:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,224
            CDSs (total)                      :: 6,161
            Genes (coding)                    :: 6,110
            CDSs (with protein)               :: 6,110
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 51
            CDSs (without protein)            :: 51
            Pseudo Genes (ambiguous residues) :: 0 of 51
            Pseudo Genes (frameshifted)       :: 16 of 51
            Pseudo Genes (incomplete)         :: 40 of 51
            Pseudo Genes (internal stop)      :: 2 of 51
            Pseudo Genes (multiple problems)  :: 7 of 51
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:37:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4971246
            Orig. end                         :: 4993392
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP118233.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22146
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="21"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22146
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22146
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12146]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12146
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(285..797)
                     /db_xref="GeneID:91358918"
                     /locus_tag="PVK74_RS22190"
                     /old_locus_tag="PVK74_22190"
     CDS             complement(285..797)
                     /codon_start=1
                     /db_xref="GeneID:91358918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018811918.1"
                     /locus_tag="PVK74_RS22190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22190"
                     /product="SRPBCC family protein"
                     /protein_id="WP_043327527.1"
                     /transl_table=11
                     /translation="MGQEMADPDEVRQESDRFSLRSNLFVPASAERAYAVFTGSLADWW
                     VREYTWSGPQALAALGIEPRAGGMLYEIGPYGFRNDWGRVLTWDPPRRLVFTWQIGPDR
                     VPVPDPAGASEVEVLFHPEGPELTRVEVEHRYFDRHGAAAEGYREALTAGWHELLCRYL
                     ATVARTA"
     misc_feature    796..811
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.65"
                     /tool="antismash"
     gene            1095..1532
                     /db_xref="GeneID:91358919"
                     /locus_tag="PVK74_RS22195"
                     /old_locus_tag="PVK74_22195"
     CDS             1095..1532
                     /codon_start=1
                     /db_xref="GeneID:91358919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283444.1"
                     /locus_tag="PVK74_RS22195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22195"
                     /product="ArsI/CadI family heavy metal resistance
                     metalloenzyme"
                     /protein_id="WP_274477120.1"
                     /transl_table=11
                     /translation="MSRVQLALRVSDLEGSVAFYSKLFGVEPAKRRPGYANFAVENPPL
                     KLVLLEGEPGLPTVMDHLGVEVATTGEVNAATSRLTESGLITLEENDTECCYALQDKVW
                     VRGPGDEPWEVYTVKADSPQLEKVTVSACCASDTAEQPAGV"
     gene            complement(1583..2167)
                     /db_xref="GeneID:91358920"
                     /locus_tag="PVK74_RS22200"
                     /old_locus_tag="PVK74_22200"
     CDS             complement(1583..2167)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91358920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018832247.1"
                     /locus_tag="PVK74_RS22200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22200"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_209959598.1"
                     /transl_table=11
                     /translation="MLHAVTGPEITVATPEDRGSVVTSLVAAFTKDPVLRHLFPDQATY
                     ARYAAVFFGHLFDKRVHKETIWTIGHGASVAIWEPPASGSAPPDDDLAAQLPADVLHRV
                     RAYDEAVHAALPSAPFWYLGVLGTHPDHAGRRWGHAVMRVGLDRAAADGLPAILETSNP
                     DNVEVYRRAGWEVVHAFAEPLPTWVMRNRRT"
     gene            complement(2219..3184)
                     /db_xref="GeneID:91358921"
                     /locus_tag="PVK74_RS22205"
                     /old_locus_tag="PVK74_22205"
     CDS             complement(2219..3184)
                     /codon_start=1
                     /db_xref="GeneID:91358921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473453.1"
                     /locus_tag="PVK74_RS22205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22205"
                     /product="PD40 domain-containing protein"
                     /protein_id="WP_064448465.1"
                     /transl_table=11
                     /translation="MRTLRTALTSVLVLAVILVGGCGRISGLLDSVSLFHPVWAADGWV
                     YYLREVTSTSGSGVAEVWRQRPDGSGEEAVLTRAPAVPACEAGLFSFLFADPDGDLGVA
                     LECGWDGTELLTYSPADKTFEPLASTRFLAGAALVNGDGRGYVQARRKCGPGGIQLLAD
                     GKASEFPSPVTVDGTTFNLSGSDTGCESMVLVRSPATMGERLFFITAPDTLGRLPLPVE
                     VYPSDFTWHLTEWDVGSATARFLAELPGLADLAVSPDGRSVIAAVASDHVGGVWSVDVD
                     TGKKTRIADGERAYHPSFSPDGKRFVYVEAFRRLRFAEAR"
     gene            complement(3353..4588)
                     /db_xref="GeneID:91358922"
                     /locus_tag="PVK74_RS22210"
                     /old_locus_tag="PVK74_22210"
     CDS             complement(3353..4588)
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91358922"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015411.4"
                     /locus_tag="PVK74_RS22210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22210"
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_274477121.1"
                     /transl_table=11
                     /translation="MKIIAVLGTGHMGTPIARRLLAGGNRVRVWNRSPERSEPLAAVGA
                     TVAASPSAAVDGAEVVVVMLADAGAVETVLFGPDGAATALRPGTVVVQMSTIGPDEVRA
                     VAGRLPAGVYLLDAPVGGSVNAARAGTLVIFAGGTADAVERAAPVLGQLGTVRHCGPIG
                     AGAAVKLVANTGLVTAVAALHDALAVAAALGVDRQTALDVLDRGALGGAVGRATAPGAS
                     FAVTMAAKDARLALRRPVPAPVLEAALDLMRAAPDQDADLSSLVSPDFCEGTLMRLTLD
                     NPESVAAPFGDRFAHVARIDVGGGALLMLAGQVAVDDDGEVVAPGDAGAQAERIFEIVG
                     GVLAAHGASFDDVLHVRTFMTDLADLSAYAAVRRRLFTGTPPPASTTVEISKLFLPGAV
                     LEVEVTAVVRSR"
     gene            4669..5565
                     /db_xref="GeneID:91358923"
                     /locus_tag="PVK74_RS22215"
                     /old_locus_tag="PVK74_22215"
     CDS             4669..5565
                     /codon_start=1
                     /db_xref="GeneID:91358923"
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020510278.1"
                     /locus_tag="PVK74_RS22215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22215"
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_113972254.1"
                     /transl_table=11
                     /translation="METQLLEVFRAVARHGSITTAARALRFTQSAVSRQIAALEADIGA
                     RLFDRLPRGVALTEEGRELLPHAEAVLDRLAAARRDLDDLRGLGRGRLRVGAFPTAVAA
                     LVPRAMASFRSAYPEVSLSLVEGVTPRLLERLLAEEADVAVVSTSPTGELDRERFDLRH
                     LLDERLLVAVARDHRLARRRSVRLADLAPEAFVVGSATAENSLLRASLPSGFSPRIDIV
                     AAEWTGKLGCVAAGLGVALVPALAVRGTPPDIALLRLHPDDESVRQIFAATVRGRTPPP
                     AVTHFLEHLRAEAAHLG"
     tRNA            complement(5629..5702)
                     /anticodon=(pos:complement(4976912..4976914),aa:Phe,
                     seq:gaa)
                     /db_xref="GeneID:91358924"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="PVK74_RS22220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="PVK74_22220"
                     /product="tRNA-Phe"
     gene            complement(5629..5702)
                     /db_xref="GeneID:91358924"
                     /locus_tag="PVK74_RS22220"
                     /old_locus_tag="PVK74_22220"
     tRNA            complement(5779..5852)
                     /anticodon=(pos:complement(4977062..4977064),aa:Asp,
                     seq:gtc)
                     /db_xref="GeneID:91358925"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="PVK74_RS22225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="PVK74_22225"
                     /product="tRNA-Asp"
     gene            complement(5779..5852)
                     /db_xref="GeneID:91358925"
                     /locus_tag="PVK74_RS22225"
                     /old_locus_tag="PVK74_22225"
     tRNA            complement(5886..5958)
                     /anticodon=(pos:complement(4977168..4977170),aa:Glu,
                     seq:ttc)
                     /db_xref="GeneID:91358926"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="PVK74_RS22230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="PVK74_22230"
                     /product="tRNA-Glu"
     gene            complement(5886..5958)
                     /db_xref="GeneID:91358926"
                     /locus_tag="PVK74_RS22230"
                     /old_locus_tag="PVK74_22230"
     gene            complement(6102..6887)
                     /db_xref="GeneID:91358927"
                     /locus_tag="PVK74_RS22235"
                     /old_locus_tag="PVK74_22235"
     CDS             complement(6102..6887)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91358927"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473455.1"
                     /locus_tag="PVK74_RS22235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22235"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_043327523.1"
                     /transl_table=11
                     /translation="MRPRALPALALGLVLLVTACGEAGKSPDQAAASPSVSASPSPVTK
                     PSPTPTATPRKPKLRPVPKKLPAGLHRASGSSGVALTFDDGPDPRYTPQILAQLRAARV
                     TATFCVVGQQAKRYPELVARIVREGHQLCNHSWHHDVNLGRRSATEIRADLERTNDAIR
                     AAAPKAPITWFRQPGGRWTAEEIVVARQMGLRPLHWSVDPQDWDHPPAKTIIKRVKGAT
                     RNGSIVLMHDAGGDRAQTMAACRHLIPDLKRRYGIARLP"
     gene            complement(6963..7910)
                     /db_xref="GeneID:91358928"
                     /locus_tag="PVK74_RS22240"
                     /old_locus_tag="PVK74_22240"
     CDS             complement(6963..7910)
                     /codon_start=1
                     /db_xref="GeneID:91358928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018255064.1"
                     /locus_tag="PVK74_RS22240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22240"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_064448346.1"
                     /transl_table=11
                     /translation="MADEALSAGAVARRLGVAVTTLRTWHQRYGLGPSEHVPGHHRRYT
                     PADLARLEIMRRLTTEGVAPAEAARWARQAPAVPPPDRLALKARTSAVRDGGGTTIPVG
                     RAGPAARGLARAAMRLDSVTIARTIAEALAADGVVATWEGLLRPVLTGIGERHAATAGL
                     IEVEHLMSRCVSVAFATVIRAHPNGGPPRILLSCADEEQHSLPLEALAAALAEAGVSCR
                     MLGARVPLPALVEAVNRTGPAAVVLWSHTRATADPCQLTALLTVPRRPLLVLAAGPGWR
                     ADSLPAGVVRPVDLAEALSLALAVRDSLDQSTKG"
     gene            complement(7900..8493)
                     /db_xref="GeneID:91358929"
                     /gene="idi"
                     /locus_tag="PVK74_RS22245"
                     /old_locus_tag="PVK74_22245"
     CDS             complement(7900..8493)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91358929"
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283449.1"
                     /locus_tag="PVK74_RS22245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22245"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_274477123.1"
                     /transl_table=11
                     /translation="MSEREEHLVELVGDDGQVLGETTVATAHQPPGRLHRAFSVLLVDP
                     QGRVLLQQRAAVKTRFPLRWANSCCGHPLPGQSLAEAANRRLGEELGVGPVELTEVGVY
                     IYYAEDPATGRVEFEYDHVLRADVPADLVTRPDPDEVAELRWADPGAVVADLDADPRAY
                     APWLGGVVNRLLHPAGPARPGVAASEAPERSGGR"
     gene            complement(8490..9971)
                     /db_xref="GeneID:91358930"
                     /gene="crtI"
                     /locus_tag="PVK74_RS22250"
                     /old_locus_tag="PVK74_22250"
     CDS             complement(8490..9971)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91358930"
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018217624.1"
                     /locus_tag="PVK74_RS22250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22250"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_274477124.1"
                     /sec_met_domain="DAO (E-value: 6.9e-18, bitscore: 63.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVKGRTDRVVVVGAGLGGLACALHLAGSGRQVTVLEREPVPGG
                     RAGRLSVDGYEFDTGPTVLTMPDLIAEALGAVGEELTDWLDLSPLDPAYRAYYPDGSTL
                     DVITDTTRMAAEIARVCGPREADGYLRFVDYARNLWQWERADFIERNLDAPTDLLTGNL
                     LKLFANGAFRRLQTKINQFFRDPRTQRIFSFQAMYAGLSPHDALAIYAVIAYLDSVAGV
                     CFPRGGIHAVSRGMAGAAEKHGVQFRYGTTVTRVETANGRATGVITSDGDFVTADTVVL
                     NPDLPVAYEDLLPPSRQRKLTYSPSCVVLHIGSTQGYGKIAHHNIHFGRSWKGTFDEVI
                     RRGELMTDPSLLVTNPSRTDPSVAPAGKHTYYVLAPVPNLERAPFDWTGDLTQRYADQL
                     VGTLEERGYVGFGDGIEVMRAVTPADWAAQGMAAGTPFAAAHSLFQTGPFRPSNLHRKL
                     DNVVFVGSGTQPGVGVPMVLISGKLAAARITGATA"
     gene            complement(10001..11155)
                     /db_xref="GeneID:91358931"
                     /locus_tag="PVK74_RS22255"
                     /old_locus_tag="PVK74_22255"
     CDS             complement(10001..11155)
                     /codon_start=1
                     /db_xref="GeneID:91358931"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019901498.1"
                     /locus_tag="PVK74_RS22255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22255"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_274477125.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.1e-47, bitscore:
                     160.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANDAVAGNALRVAPAQAGATDDPVRGVLAAFTKDLIKGVDETLV
                     AFLAAEVDSLTEIDAAMGAFAATARDCVLAGGKRVRPTFAYWGWRGAVGGEEPMCSALP
                     ALSALELLHTFALVHDDVMDASDTRRGLPTAHRAAAARHRAAGHAGDPDRYGEAVAVLI
                     GDLCMVWADRLMGHAAVPAERLLDVRRCYDQMRVETVAGQFLDVLGENDAGNWTVDRAL
                     RVARYKTASYTVQRPLLFGACLAGTDPDDPLIAAYTRYGLAVGEAFQLRDDLLGVYGDP
                     ETTGKPAGDDLRTGKPTALLMLARQLADPAQRRALDRAGSVTTARDVDRLADVVRDTGA
                     TARVERMIADRVTEALAALGTAPIDETARTALTGLATAATARRA"
     misc_feature    complement(11156..11174)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.7"
                     /tool="antismash"
     gene            11220..12146
                     /db_xref="GeneID:91358932"
                     /locus_tag="PVK74_RS22260"
                     /old_locus_tag="PVK74_22260"
     CDS             11220..12146
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91358932"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785446.1"
                     /locus_tag="PVK74_RS22260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22260"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_043327518.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.7e-113,
                     bitscore: 376.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.6e-64,
                     bitscore: 216.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVDLAAAYDRCRELHRRHGRTYYLATRLLPAWKRRHVHALYGFT
                     RYADEIVDRTEDLPPAERAARLREWSDRFVAGLHGASVDDPLLPAVLHTIAVFDLDRDD
                     FASFLRSMAMDLTVMSYPTYDDLLDYMEGSAAVIGTMMLPILGSSDPAAAREPARQLGF
                     AFQLTNFIRDVAEDLDRGRTYLPDEDLAKFDVTRADLVAAKAAGRTTPRIRELIEYEVT
                     RAQAHYLAAAPGIPLLNPASQACMRTAYALYGGILDEVAAQDYDVFVRRALVPQRRRMA
                     VAARALLTPPGTPVQVPGPALEPALAG"
     gene            12143..13465
                     /db_xref="GeneID:91358933"
                     /locus_tag="PVK74_RS22265"
                     /old_locus_tag="PVK74_22265"
     CDS             12143..13465
                     /EC_number="4.1.99.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003904 - deoxyribodipyrimidine
                     photo-lyase activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91358933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283453.1"
                     /locus_tag="PVK74_RS22265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22265"
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="WP_274477126.1"
                     /transl_table=11
                     /translation="MTGRTAVVLFTRDLRVHDHPALAAACSAFERVVPLYVLDPELQQL
                     SPNRTRFLHQSLADLREALRKRGGDLVIRRGDPVAETVKLARKVGAEGVGLSADVSHYA
                     RRRERRLRAECDRHRMFLRLFPGLTIVEPGALRPSGGDHYRVFSPYFRAWQGVRLRDEL
                     AAPKRVRLPDGVDPGRLPDPPKGDSPAAAVGGENAARRRLTAWLPTLDRYDDIHDDMAG
                     DETSRLSPYLRFGCVSPLAVATRAGDRDGPFVRQLCWRDFYHQVVAGFPDLSTAAYRRG
                     AREDWRYDEHALDAWTEGRTGMPIVDAGMRQMRAEGWMHNRARLITAGYLTKHLGLDWR
                     PGLEVFFRWLLDGDRVNNSGNWQWVAGTGNDTRPYRGFNPVRQAERYDPDGAYVRRWVP
                     ELESVAGKAVHQPWRLPDAVRRTLDYPPPLEVPGADPVWLR"
     gene            complement(13828..14928)
                     /db_xref="GeneID:91358934"
                     /locus_tag="PVK74_RS22270"
                     /old_locus_tag="PVK74_22270"
     CDS             complement(13828..14928)
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91358934"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473461.1"
                     /locus_tag="PVK74_RS22270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22270"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_274477127.1"
                     /transl_table=11
                     /translation="MHTRFTPVRDCFHDLFVTGRETGASLAVWHDGVPVIELMGGTAAA
                     VPPSAVAPMAGADRAWRPDTLVDVYSTGKPVVALCLLLLVDRGRVDLDTPVSAYWPEFR
                     TPATVRQVLAHTAGLPAFPVPRPAAAIADWGLLCADLATAEPEWDPGAVAGEHAWTYGH
                     LVGELVRRVDGRPVGRFLAEEIAGPWRLDLAFGLGETDRRRCADLSYADPAWPDAMRGE
                     PGSLRARALDNPPGGRDVAMVNSDLWRAAEIPAVNLHATAAGLARLYAGLLASGTLDGV
                     RLFSPELVAEATRVQYSGPDLLLDRPVDWTLGMQWEPDGSWGMGGIGGSSAWADPERGY
                     TFAYATARLADHDRVEELVEALHSCL"
     gene            15021..16505
                     /db_xref="GeneID:91358935"
                     /locus_tag="PVK74_RS22275"
                     /old_locus_tag="PVK74_22275"
     CDS             15021..16505
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91358935"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283455.1"
                     /locus_tag="PVK74_RS22275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22275"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_274477128.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1e-44, bitscore:
                     151.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEPEQVDVVVVGLGVGGEEVAGRLAEAGLTVVGIERDLVGGECP
                     YWGCVPSKMMIRAANALAEAHRVNELAGSAQVRPDWAPVAKRIRAEATDTWDDKVAVDR
                     FTGKGGRFVRGSGRLDGPNRVRVGDQVFQARYGVVLGTGTRPSVPPIDGLADTPYWTNH
                     QAIEVEELPASLLVLGGGAIGLELAQVFARFGVRVTVIEAADRVLAVEEPEASALAADA
                     LRADGVEIHTGVKAGRVGHDGGAFTVYADGAEFTGEKLLVVTGRKAHLEELGLDTVGVD
                     AGQRYLPVNDRMHVTEGIWAVGDLTGEGAFTHIAMYQAGIVVADVLDHMRRTKGGPDAS
                     GTASVVGGAAGVVSSVGGAMSAGGSSVAPGSVPVADYRALPRVTFTDPEVGAVGLTEQQ
                     ARERGVNVQVGYADLTSSARGWIHKTGNAGFIKLVADADQGVLIGATSAGPAGGEVLSA
                     LVVAVHAAVPISQLRHMIYAYPTFHRAISDALRALK"
     gene            complement(16510..17274)
                     /db_xref="GeneID:91358936"
                     /locus_tag="PVK74_RS22280"
                     /old_locus_tag="PVK74_22280"
     CDS             complement(16510..17274)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (5-208). E-value: 7e-43. Score:
                     138.6. Matches aSDomain:
                     nrpspksdomains_PVK74_RS22280_ECH.1"
                     /codon_start=1
                     /db_xref="GeneID:91358936"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785442.1"
                     /locus_tag="PVK74_RS22280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22280"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_274477129.1"
                     /transl_table=11
                     /translation="MGVRVEHAGAVTTVILDRPEARNAVDGPTARALADAFRAFDADPD
                     AAVAVLWGAGGTFCSGADLKAVGTPRGNRVEPEGDGPMGPTRMRLSKPVIAAISGYAVA
                     GGLELALWCDLRIAESDATLGVFCRRWGVPLIDGGTVRLPRLIGESRAMDLILTGRPVG
                     ADEAYAMGLVNRLVAPGAARAAAEELAAAIARSPQTCLRNDRAAVLDGTGRPEPEAMAT
                     ELAYGMESLAVDGVRGAGRFAAGAGRHGAPAG"
     aSDomain        complement(16651..17259)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PVK74_RS22280_ECH.1"
                     /evalue="7.00E-43"
                     /label="PVK74_RS22280_ECH.1"
                     /locus_tag="PVK74_RS22280"
                     /protein_end="208"
                     /protein_start="5"
                     /score="138.6"
                     /tool="antismash"
                     /translation="EHAGAVTTVILDRPEARNAVDGPTARALADAFRAFDADPDAAVAV
                     LWGAGGTFCSGADLKAVGTPRGNRVEPEGDGPMGPTRMRLSKPVIAAISGYAVAGGLEL
                     ALWCDLRIAESDATLGVFCRRWGVPLIDGGTVRLPRLIGESRAMDLILTGRPVGADEAY
                     AMGLVNRLVAPGAARAAAEELAAAIARSPQTCLRNDRAAV"
     gene            complement(17315..17740)
                     /db_xref="GeneID:91358937"
                     /locus_tag="PVK74_RS22285"
                     /old_locus_tag="PVK74_22285"
     CDS             complement(17315..17740)
                     /codon_start=1
                     /db_xref="GeneID:91358937"
                     /inference="COORDINATES: protein motif:HMM:NF013970.4"
                     /locus_tag="PVK74_RS22285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22285"
                     /product="PIN domain nuclease"
                     /protein_id="WP_274477130.1"
                     /transl_table=11
                     /translation="MKLADYLIDTSALVRLLRDPDVLARWEQQVTAGLLAVCPLVELEF
                     LYTARSVADRTRLTEQLRAAFGWVVMPDRIYERAAEIQGELTVRGTHRSAGAVDLLIAA
                     TAEYHGLSLLHYDRDFDQVGAVTGQPMRWLTRPGSIK"
     gene            complement(17737..17946)
                     /db_xref="GeneID:91358938"
                     /locus_tag="PVK74_RS22290"
                     /old_locus_tag="PVK74_22290"
     CDS             complement(17737..17946)
                     /codon_start=1
                     /db_xref="GeneID:91358938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020512679.1"
                     /locus_tag="PVK74_RS22290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22290"
                     /product="type II toxin-antitoxin system VapB family
                     antitoxin"
                     /protein_id="WP_030500628.1"
                     /transl_table=11
                     /translation="MTKILVDVDDEALADAAEAFGTKTKKDTVNVALREGAARLRRARA
                     LAELAERGQAGDFDELLDKGAYRS"
     gene            18057..18908
                     /db_xref="GeneID:91358939"
                     /locus_tag="PVK74_RS22295"
                     /old_locus_tag="PVK74_22295"
     CDS             18057..18908
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91358939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785440.1"
                     /locus_tag="PVK74_RS22295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22295"
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="WP_274477131.1"
                     /transl_table=11
                     /translation="MRELLTKIEQATGLDRVGDRLQRAVQGTLRSQRVRDALHGVWLGH
                     PLHPAMVQVPVGAWISAAVVDLLPGQRRAATALVGLGTVSALPAAVAGLNDWATLSRDQ
                     RRIGLVHAAANTVGLALYAGSLAARLNGRHGLGRALSYLGLSAASGGAYLGGHLAYKQG
                     AQASQSVSELHLISDGWHRVGDLGSLPRHELVTKKIDDVSVILYRDGDDVTVMLERCPH
                     QSGPLGEGTVEQIDGHACVVCPWHGSAFRLNGGEVVHGPAANDQIVLPTRVVSGQVEAR
                     LP"
     gene            complement(18910..19920)
                     /db_xref="GeneID:91358940"
                     /locus_tag="PVK74_RS22300"
                     /old_locus_tag="PVK74_22300"
     CDS             complement(18910..19920)
                     /GO_function="GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91358940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473464.1"
                     /locus_tag="PVK74_RS22300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22300"
                     /product="LysM domain-containing protein"
                     /protein_id="WP_274477132.1"
                     /transl_table=11
                     /translation="MGAPRRSPVRRAGQVLTGLGALVVLVGVLAGGPVALLAFAGNPLP
                     DNLPTFAEIGTTLTSRDDGQLFLRALAVVGWFGWATFTFSVVVELLAAAVRRPAPKLPG
                     MHRQQKAAAALVGSVALILAASPAAASAAALTAPQPAVAASAVTAPSRVAPPAPVASKA
                     DDPAVYRVAKGDYLGEVADRYLDDFDRYKELARMNRLADPDRIRPGQLITLPDGATDSG
                     ARRHATGRLVVTKPAQTAPVKPGGGGASSSAPKAKPKPTPRDATPTVEAPVGQPPAMSA
                     GASRPTAEEGINRPLAISAVLAVASIVGAQIGALLGLRKRPVPARAGSSGRHRRD"
     gene            complement(19936..20367)
                     /db_xref="GeneID:91358941"
                     /locus_tag="PVK74_RS22305"
                     /old_locus_tag="PVK74_22305"
     CDS             complement(19936..20367)
                     /codon_start=1
                     /db_xref="GeneID:91358941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785438.1"
                     /locus_tag="PVK74_RS22305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22305"
                     /product="hypothetical protein"
                     /protein_id="WP_274477133.1"
                     /transl_table=11
                     /translation="MTGRRAAENGRVSLFLAVAMTGVLAIISLAYDGAGQLRTLQRADN
                     LAAEAARAGGQMIDRARAIEGGPKQIDQVAARAAVAAYLDAAGGVQDHEVDFPVVGAET
                     QIRVSVQITYSRDLLSLFGVQNTATVTGEATARALTGPP"
     gene            complement(20364..20837)
                     /db_xref="GeneID:91358942"
                     /locus_tag="PVK74_RS22310"
                     /old_locus_tag="PVK74_22310"
     CDS             complement(20364..20837)
                     /codon_start=1
                     /db_xref="GeneID:91358942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283460.1"
                     /locus_tag="PVK74_RS22310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22310"
                     /product="TadE/TadG family type IV pilus assembly protein"
                     /protein_id="WP_274477134.1"
                     /transl_table=11
                     /translation="MSAGPRRDRGSVSIEVAVLAPAFIGLMVLAGVAGRTAIADEAVES
                     AAHDAARAASLARNADDGAEAAEEAAQDQLGWAGLNCTGPPQIDLAGSVAGTTTSFAAA
                     YASAAGVPATVTVTVTCTVSFDDLSAPGLPGVPGGKTVSARFTSPLDTYRSRG"
     gene            complement(20834..21316)
                     /db_xref="GeneID:91358943"
                     /locus_tag="PVK74_RS22315"
                     /old_locus_tag="PVK74_22315"
     CDS             complement(20834..21316)
                     /codon_start=1
                     /db_xref="GeneID:91358943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473467.1"
                     /locus_tag="PVK74_RS22315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22315"
                     /product="TadE/TadG family type IV pilus assembly protein"
                     /protein_id="WP_069088178.1"
                     /transl_table=11
                     /translation="MPRPARTVRSRPAPAGRPAGPPGPGRIAAALRARLAEGERGANPV
                     ELAVVMPVILVMLFGSIQVAVWFVARSTALNAAQTGVNAQRTIDAGPDAGRERAISFLQ
                     QSGDWLVGWEQTGPTCVETATAVTCTVQGRSLSVIPGVSFAVTQTAHGPAERWTTG"
     gene            complement(21316..21525)
                     /db_xref="GeneID:91358944"
                     /locus_tag="PVK74_RS22320"
                     /old_locus_tag="PVK74_22320"
     CDS             complement(21316..21525)
                     /codon_start=1
                     /db_xref="GeneID:91358944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283462.1"
                     /locus_tag="PVK74_RS22320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_22320"
                     /product="hypothetical protein"
                     /protein_id="WP_013283462.1"
                     /transl_table=11
                     /translation="MHLYAYLYVAVSTRLAELRRDSERGDSPVPTAVIIFGLVAVAMAV
                     TGLALAKANNWMNAIPNNTAPQAP"
     misc_feature    21776..21790
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
ORIGIN
        1 gcgtacgtcg tcgcgcagcg gctgcgcgca gccgaggaga acgcggtggc cgaggcgggc
       61 ggcccctcga cggccctggt actcgccgac cgttccgacc gcgtccagcg ccgggtcgcc
      121 gaggcgtacc ccaggttgcg caccgcgccg cgacggcgcc tcgcgggcgg tggtttcgcg
      181 ccgggcgcgg acgccggccg ccgcgccgac ctcggcggca ccggcgtgcc cggcgccgcg
      241 gcgacgccgg gcatcaccgg ctgaccgggc ccatcgggta cgggtcaggc ggtgcgggcg
      301 accgtcgcca ggtagcggca gagcaactcg tgccagccgg ccgtgagcgc ctcgcggtag
      361 ccctcggccg cggcgccgtg ccggtcgaag tagcggtgct cgacctcgac ccgggtcagt
      421 tccgggccct cggggtggaa caggacctcc acctcgctgg cgccggcagg gtccggcacc
      481 ggcacccggt ccgggccgat ctgccaggtg aagaccagac gccggggcgg atcccaggtc
      541 agcacgcggc cccagtcgtt gcggaagccg tacgggccga tctcgtagag catgccgccg
      601 gcccggggtt cgatgccgag cgcggcgagc gcctgcgggc cggaccaggt gtactcgcgt
      661 acccaccagt cggcgagcga tccggtgaac acggcgtacg cccgctcggc cgacgccggg
      721 acgaacaggt tgctgcggag ggagaagcgg tcggattcct gccggacctc atccggatcg
      781 gccatctcct gtcccatagg tccggaccat accggctcat gtctcggtgc gcagcttccg
      841 ttgcgcccgc ttccggacac cgggaacgcc gctccacgac agcgctgtgt ggtgggacag
      901 gcgcgccgag ttggcggaac gcctcggggc gtacccggta ccaggcccag gtgccgcgcc
      961 gctcggagcc ggacgcagat ctccgacgcc gaggcgccgg cagcgcttgt ttcgacattt
     1021 ctctaggttg acagacttca aagcagaggg cagggtgggg tctgcttcga taaacatcta
     1081 gacagggggt tcacatgtcc cgcgtccagc tcgccctgcg cgtgtccgac ctcgaaggct
     1141 ccgtggcctt ctacagcaag ctgttcggcg tcgagccggc caagcgccgc cccggctacg
     1201 ccaacttcgc ggtggagaac ccgccgctga agctcgtact cctcgaaggt gagcccggcc
     1261 tgccgacggt gatggaccac ctcggggtcg aggtggccac caccggcgag gtgaacgccg
     1321 cgaccagccg gctcaccgag tccggcctga tcacgctgga ggagaacgac accgagtgct
     1381 gctacgcgct ccaggacaag gtctgggtgc gcggccccgg cgacgagccg tgggaggtct
     1441 acacggtcaa ggccgactca ccgcagctgg agaaggtgac cgtgagcgcc tgctgcgcct
     1501 cggacactgc ggagcagccc gccggcgtct gaacggcgga tccccaccgg cgtctccgcc
     1561 ggtggggatc tctgtcgtac ggtcaggtgc ggcgattccg catgacccag gtgggcagcg
     1621 gttccgcgaa ggcgtgcacc acctcccagc cggcgcgccg gtacacctcg acgttgtccg
     1681 ggttgctggt ctccagaatc gccggcaggc cgtccgcggc ggcccggtcc agccccaccc
     1741 gcatcacggc gtggccccac ctgcggccgg cgtggtccgg gtgcgtaccc agcaccccca
     1801 ggtaccagaa cggcgccgac ggcagcgcgg cgtgcaccgc ctcgtcgtag gcgcggacgc
     1861 ggtgcaacac gtcggcggga agctgggcgg cgagatcgtc gtccggcggg gcgctcccgg
     1921 atgccggcgg ctcccagatc gccaccgacg cgccgtgccc gatcgtccag atcgtctcct
     1981 tgtgcacccg cttgtcgaac aggtgcccga agaagacggc cgcataacgc gcataggtcg
     2041 cctggtcggg gaacaggtgc cgcaggaccg gatccttggt gaacgccgcg accagcgagg
     2101 tgaccacgct gccacggtct tccggcgtcg caacggtgat ctcaggccct gtcacagcgt
     2161 gcaacatatc gtgcggccga ggcgcggggc gtccctcgcg gcgtgagccg gccggcgact
     2221 accgtgcctc ggcgaacctc agccgcctga aggcctcgac gtagacgaac cgcttgccgt
     2281 ccggagagaa gctcgggtgg tacgcgcgct caccgtcggc gatccgcgtc ttcttcccgg
     2341 tgtcgacgtc gaccgaccac acgccgccca cgtgatccga cgcgacggcg gcgatcaccg
     2401 acctgccgtc cggcgacacc gccaggtcgg cgagcccggg aagctccgcg aggaacctgg
     2461 ccgtggccga tccgacgtcc cactcggtca ggtgccaggt gaagtcagac ggatacacct
     2521 cgacaggcag cggcaacctg ccgagggtgt cgggtgcggt gatgaagaac agccgctcac
     2581 ccatggttgc cggcgaccgc accagcacca tggactcgca acccgtatca ctgccactga
     2641 ggttgaaggt tgtcccgtcg accgtcaccg gagaggggaa ctcagacgcc ttcccgtcag
     2701 cgagcagctg gattcccccc ggcccgcact tccggcgcgc ctgcacatat cccctgccgt
     2761 caccgttcac gagtgcggca ccggcgagga agcgcgtcga cgccagaggc tcgaacgtct
     2821 tgtcggccgg cgagtaggtg agcagctccg ttccgtccca gccgcattcg agggccaccc
     2881 cgaggtcgcc gtcggggtcg gcgaacaaga agctgaacaa gcccgcttcg caggcgggca
     2941 ccgccggggc gcgcgtgaga acggcttcct cgccgctccc gtcgggccgc tgccgccaca
     3001 cctcggctac tcccgagccc gaggtcgagg tcacctcccg caggtagtag acccagccgt
     3061 cggcggccca caccggatgg aacagggaga cggaatccag gagccccgag atccggccgc
     3121 acccgcccac caggatcacg gccagtacga ggaccgacgt cagagccgta cgcagcgtcc
     3181 gcacacgcga ccttctggtg ctcacctgcc tcattccgtc cgtcactcag cgggctcacc
     3241 gtaggcgccg ccgccgttgc cggggaccgt acacccgtta ggtactcagg gtggcgacct
     3301 gtgccggccg tggatacggc ccgtcggccg ggaagcgcaa tcgtcgcgac acctagcggg
     3361 accggaccac ggccgtgacc tcgacctcga gcacggcacc gggcaggaag agcttgctga
     3421 tctcgacagt cgtgctcgcc ggcggcggtg tgccagtgaa gagtcggcgc cggacggccg
     3481 cgtacgccga caggtcagcc aggtccgtca tgaacgtgcg gacgtgcagc acgtcgtcga
     3541 agctcgcgcc gtgcgccgcg agcacgccgc ccacgatctc gaagatccgt tcggcctggg
     3601 cgccggcgtc tccgggggcc accacctcgc cgtcgtcgtc gacggcgacc tgtccggcga
     3661 gcatcagcag cgcgccgccg ccgacatcga tccgggcgac gtgcgcgaag cggtcgccga
     3721 acggggccgc gacggattcg gggttgtcca gggtgaggcg catcagcgtc ccttcgcaga
     3781 agtcggggga gacgagggag gagagatcgg cgtcctggtc cggcgcggcc cgcatcaggt
     3841 cgagggcggc ctccagcacg ggggccggca ccgggcggcg cagcgccagc cgcgcgtcct
     3901 tcgccgccat cgtgactgcg aacgaggcgc ccggggcggt ggcccgtccg accgcgccgc
     3961 cgagggcccc acggtcgagc acgtcgaggg cggtctgcct gtcgacaccg agcgccgcgg
     4021 cgacagccag cgcgtcgtgc agcgcggcga cagccgtcac caaacccgtg ttcgcgacga
     4081 gtttgacggc ggcacctgcg ccgatcggac cgcagtggcg gaccgtcccg agctgcccca
     4141 gcaccggagc cgccctctcc acggcatcgg cagtgccgcc cgcgaagatc accagcgtgc
     4201 cggcccgggc ggcgttgacg ctgccgccga cgggggcgtc gaggaggtag acgcccgccg
     4261 gaagccggcc ggccaccgct cggacttcgt ccggcccgat cgtcgacatc tgcaccacga
     4321 ccgtcccggg tcggagcgcg gtggcggcgc cgtccggccc gaacagcacc gtctcgaccg
     4381 cgccggcgtc ggcgagcatg acgacgacga cctcggctcc gtcgaccgcg gcggacgggc
     4441 tcgcggccac cgtcgcgccg accgccgcga gcggctccga gcgctccggg ctgcggttcc
     4501 acactctgac ccggttgccg ccggccagga ggcggcgcgc gatcggcgta cccatgtgcc
     4561 cggtcccgag gaccgcgatg atcttcacgc ggtaacgcta ggccggtgaa agcaatgcga
     4621 caaacgaatg tcttgcatgc ctgccatgcg tgattaccat gcctgcccat ggagactcag
     4681 ctgctggagg tgttccgcgc cgtcgcgcgg cacggctcga tcaccaccgc cgcccgcgca
     4741 ctccgcttca cccagtcggc tgtctcccgg cagatcgccg cgctcgaggc cgacatcggc
     4801 gcccggctct tcgaccggct gccccgcggc gtcgccctca ccgaggaggg acgagagctg
     4861 ctcccgcacg ccgaggcggt cctcgaccgg ctcgccgcgg cccggcgtga cctcgacgac
     4921 ctgcgcgggc tcggccgagg gcggctgcgt gtgggcgcct tcccgaccgc tgtcgcggcc
     4981 ctcgtacccc gggcgatggc gtcgttccgc tcggcctacc cggaggtctc gctttcgctg
     5041 gtcgagggcg tgacgccgcg gctgctggag cgcctgctcg ccgaggaggc ggatgtggca
     5101 gtggtcagca cctcgcccac gggcgagctg gaccgcgaac gattcgacct gcgacacctg
     5161 ctcgacgagc ggctcctggt cgcggtcgcg cgtgaccacc ggctggcgcg ccgccgctcg
     5221 gtgcgcctgg cggacctcgc cccggaagcg ttcgtcgtgg gctcggccac cgcggagaac
     5281 agcctgctcc gcgcaagcct gcccagcggt ttctcgccgc gcatcgacat cgtcgcggcc
     5341 gagtggaccg gcaagctggg atgcgtcgcc gccgggttgg gggtggccct ggttccggcc
     5401 ctggcggtac gcggaacccc gccggacatc gccctgctcc gcctgcaccc ggacgacgag
     5461 tcggtacggc agatattcgc ggcgaccgtg cggggcagga cgccgccgcc ggcagtcacg
     5521 catttcctgg agcacctgcg ggcggaggcg gcccatctgg gctgaaaagc agaacgccga
     5581 cctgcgtatc cgctggtcgg cgttcctgta gcccggcgaa aggctatgtg gccaggggcg
     5641 gggtcgaacc gccgaccttc cgattttcag tcggacgctc gtaccaactg agctacctgg
     5701 ccgtggtgct cggcacatgc taccgcatga gccgatacgc agaacgccgc gcattgagct
     5761 gcgcggcgtc agcgcttgcg gtcctgacgg gacttgaacc cgcgacctcc gccttgacag
     5821 ggcggcgagc actccaactg ctccacagga cctggctggt gttgcatccg gcgcgagccg
     5881 gaccgtgccc ccaacgggat tcgaacccgt gctaccgcct tgaaagggcg gcgtcctggg
     5941 ccgctagacg atgagggcgg ccccgccatc attgcacact cgcaacttca agcggacttg
     6001 ctcccatccg gccccgccgg aggcaggaga agcatatgtc atgtctgcac ggacggccaa
     6061 accggtatgg gcatggccgc gacgccgggc aaaaccgcag gtcagggtag tcgcgcgatg
     6121 ccgtaccgcc gcttcaggtc cgggatcagg tgccggcacg cggccatcgt ctgggcccgg
     6181 tcaccgcccg cgtcgtgcat cagcacgatc gagccgttcc gggtggcgcc cttcacccgc
     6241 ttgatgatcg tcttcgccgg cgggtggtcc cagtcctgcg ggtccacgct ccagtgcagc
     6301 gggcgcaggc ccatctgccg ggccaccacg atctcctcgg cggtccaccg gccgccgggc
     6361 tggcggaacc aggtgatcgg cgccttgggc gcggcggcgc ggatggcgtc gttggtccgt
     6421 tccaggtcgg cccggatctc ggtggccgac cgccggccga ggttcacgtc gtggtgccag
     6481 ctgtggttgc agagctggtg accctcgcgg acgatccggg ccaccagctc cgggtagcgc
     6541 ttggcctgct ggccgaccac gcagaacgtc gcggtgaccc gggccgcccg gagctgggcc
     6601 aggatctgcg gggtgtagcg gggatccggt ccgtcgtcga aggtgagcgc caccccgctg
     6661 ctcccgctgg cccggtgcag gcccgccggg agcttcttgg gcaccgggcg cagcttcggc
     6721 ttcctggggg tggcggtcgg ggtcggtgag ggcttcgtca cgggcgacgg cgacgccgag
     6781 accgacggcg aggccgccgc ctgatcgggt gacttgccgg cttcgccgca ggcggtgacg
     6841 aggagcacca ggcccagggc gagcgccggc agggcgcgtg gacgcattcg tcgctcccgg
     6901 aggggtcggg gtcagacgga ctttccgacc gtagtggacg cgccccggag cgaaaagggc
     6961 cgtcagccct tcgtcgactg gtccagcgag tcccgtaccg ccagggcgag ggagagcgcc
     7021 tcggccagat ccaccggccg gaccaccccg gccggcagcg agtcggcccg ccagccgggc
     7081 ccggcggcga gcaccagcag cggccggcgg gggacggtca gcagcgcggt gagctggcac
     7141 gggtcggcgg tcgcgcgggt gtgcgaccag aggaccacgg ccgccggccc ggtccggttg
     7201 accgcctcca ccagggcggg caacggcacc cgggcgccga gcatgcgaca gctcacaccg
     7261 gcctccgcga gcgcggcggc gagcgcctcc agcggcaacg agtgctgttc ctcgtcggcg
     7321 caggagagca ggatccgggg cggtccgccg ttcgggtggg cccggatcac cgtggcgaac
     7381 gccaccgaga cgcaccggga catcaggtgt tccacctcga tcaggccggc ggtggcggcg
     7441 tgccgttccc cgatcccggt gagcaccggc cggagcagcc cctcccaggt cgccaccacc
     7501 ccgtcggcgg cgagcgcctc ggcgatggtc cgcgcgatgg tcaccgagtc caggcgcatc
     7561 gcggcacggg ccagcccccg tgcggcgggg ccggcccggc cgaccgggat ggtcgtgccg
     7621 ccgccgtcgc gtaccgccga ggtccgtgcc ttgagcgcga gccggtccgg cggcggcacg
     7681 gccggggcct gccgggccca gcgggccgcc tcggcgggcg ccaccccctc ggtggtcagc
     7741 cggcgcatga tctccaggcg ggcgaggtcg gcgggcgtgt agcgccggtg gtggcccggc
     7801 acgtgctcgc tgggaccgag gccgtaccgc tggtgccagg tgcgcagcgt ggtgaccgcc
     7861 acacccaacc ggcgtgccac ggcccccgcg ctcagcgcct catcggccac ccgaccgctc
     7921 cggtgcctcg gaggccgcga cgcccggccg ggccgggccc gccggatgca gcagccggtt
     7981 gaccacgccg cccagccacg gggcgtacgc gcgggggtcg gcgtccaggt cggccaccac
     8041 cgcgccgggg tcggcccagc gcagctcggc cacctcgtcc ggatcgggcc gcgtcaccag
     8101 gtcggcgggt acgtcggcgc gcagcacgtg gtcgtactcg aactcgacgc ggccggtcgc
     8161 cgggtcctcg gcgtagtaga tgtagacgcc cacctcggtg agctcgaccg ggccgacgcc
     8221 gagttcctcg ccgagccgcc ggttggcggc ctcggccagc gactggcccg gcagcgggtg
     8281 cccgcagcag gagttcgccc agcgcagcgg aaaccgcgtc ttcaccgcgg cccgctgctg
     8341 cagcagcacc cgcccctgcg ggtcgaccag gagcaccgag aaggcccggt gcagccggcc
     8401 gggtggctgg tgggcggtcg ccacggtggt ctcgccgagc acctgcccgt cgtcgccgac
     8461 cagctcgacc aggtgttcct cccgctcgct catgccgtcg ccccggtgat ccgggccgcc
     8521 gcgagcttgc cgctgatcag caccatcggt acccccacgc ccggctgcgt gccggagccg
     8581 acgaagacca cgttgtccag cttccggtgc aggttggagg ggcggaacgg cccggtctgg
     8641 aagaggctgt gcgcggcggc gaacggcgtg ccggcggcca tgccctgcgc cgcccagtcg
     8701 gccggggtga cggcccgcat cacctcgatg ccgtcgccga agccgacgta tccgcgttcc
     8761 tccagcgtgc ctacgagctg gtcggcgtac cgctgggtga ggtcgcccgt ccagtcgaac
     8821 ggcgcccgct ccaggttcgg caccggcgcc agcacgtagt aggtgtgctt cccggccggc
     8881 gccaccgacg ggtcggtgcg gctcgggttc gtcaccagca gcgacgggtc ggtcatcagc
     8941 tcgcctcggc ggatcacctc gtcgaacgtc cccttccagg agcgcccgaa gtggatgttg
     9001 tggtgggcga tcttgccata gccctgcgtc gaaccgatgt gcagcaccac gcaggacggc
     9061 gagtaggtga gcttgcgttg ccggctgggc ggcagcaggt cctcgtaggc gaccggcagg
     9121 tcggggttga gcaccaccgt gtcggcggtg acgaagtcgc cgtcggaggt gatcacgccg
     9181 gtggcgcggc cgttggcggt ctccacccgg gtcaccgtgg tgccgtaccg gaactgcacg
     9241 ccgtgcttct cggccgcgcc ggccatcccg cgggagaccg cgtggatgcc gccgcgcggg
     9301 aagcagacac cggccaccga gtcgaggtac gcgatgaccg cgtagatcgc cagcgcgtcg
     9361 tgcggcgaca ggcccgcgta catggcctgg aaggagaaga tccgctgggt acgcgggtcg
     9421 cggaagaact ggttgatctt cgtctggagc cgccggaagg cgccgttggc gaacaacttc
     9481 agcaggttgc cggtgagcag gtcggtcggc gcgtcgaggt tgcgctcgat gaagtcggcc
     9541 cgttcccact gccacaggtt gcgggcgtag tcgacgaaac gcaggtagcc gtccgcctcc
     9601 cggggaccgc agacacgcgc gatctcggcc gccatccggg tggtgtcggt gatgacgtcg
     9661 agcgtcgacc cgtccgggta gtaggcgcgg tacgccgggt cgagcgggct caggtcgagc
     9721 cagtcggtca gctcctcgcc gaccgcgccg agcgcctcgg cgatcaggtc gggcatggtg
     9781 aggacggtcg ggccggtgtc gaactcgtac ccgtcgacgc tgagccgccc ggcgcgcccg
     9841 ccgggcaccg gctcgcgctc cagcaccgtc acctgccggc cgctgccggc caggtgcagc
     9901 gcgcacgcca gtccacccag cccggcgccg accaccacca cccggtcggt ccgtcccttg
     9961 acggtacgca ttccggcccc cttgctcgcg aagttgctca tcatgcccgc cgcgcggtgg
    10021 cggcggtggc gagacccgtc agcgcggtgc gcgcggtctc gtcgatcggt gcggtgccga
    10081 gcgcggcgag cgcctcggtg acccggtcgg cgatcatccg ttccacccgg gcggtggcgc
    10141 cggtgtcgcg gaccacgtcg gcaagccggt ccacgtcgcg tgccgtggtg accgagccgg
    10201 cccggtccag cgcccggcgc tgcgccgggt cggcgagttg ccgggccagc atcagcagcg
    10261 cggtcggctt gccggtacgc aggtcgtccc cggccggctt gccggtggtc tccgggtcgc
    10321 cgtagacgcc gagcaggtcg tcgcggagct ggaacgcctc gccgacggcc agcccgtacc
    10381 gggtgtacgc ggcgatgagc gggtcgtccg ggtcggtgcc ggccaggcag gcgccgaaga
    10441 gcagcggccg ctggacggtg tagctggcgg tcttgtaccg ggccacccgt agcgcccggt
    10501 cgaccgtcca gttccccgcg tcgttctcgc cgagcacgtc caggaactgc ccggcgaccg
    10561 tctccacccg catctggtcg tagcagcggc gcacgtcgag cagccgctcg gcggggaccg
    10621 ccgcgtggcc catgagccgg tcggcccaca ccatgcagag gtcgccgatg agtacggcga
    10681 ccgcttcgcc gtaccggtcg gggtcgcccg cgtgcccggc ggcgcggtgc cgggcggcgg
    10741 cggcccggtg cgcggtcggc agcccgcgcc gggtgtcgga ggcgtccatc acgtcgtcgt
    10801 gcacgagtgc gaacgtgtgc agcagttcga gggcggacag ggccgggagc gccgaacaca
    10861 tcggttcctc cccgccgaca gcgccccgcc atccccagta cgcgaacgtg ggccggaccc
    10921 gtttgccgcc ggccagcacg cagtcgcgcg cggttgcggc gaatgcaccc atcgctgcgt
    10981 cgatctcggt cagcgaatcg acttccgcgg ccaggaacgc caccagcgtc tcatcgaccc
    11041 ctttgatcag gtctttcgtg aacgcggcca gtacgccgcg gaccggatcg tccgtcgccc
    11101 cggcctgagc cggcgcgacg cggagcgcat tacccgcaac tgcgtcgttg gccatgtggg
    11161 cgagcgtacc ctagggttac gagttgcgtc gattgctgcg tcgaaactga ggagggccga
    11221 tggacgtgga tctggccgcc gcctatgacc gctgccgcga gctgcaccgg cgtcacggcc
    11281 gtacctacta tctcgccacc cggctgctcc ccgcctggaa acggcgacat gtgcacgcct
    11341 tgtacggatt cacccgctac gcggacgaga tcgtcgaccg caccgaggac ctgccgcccg
    11401 ccgagcgcgc ggcccggctg cgcgagtggt cggatcgatt cgtggccggg ctgcacggcg
    11461 cgtcggtcga cgacccgctg ctccccgccg tgctgcacac catcgccgtg ttcgacctgg
    11521 accgcgacga cttcgcgtcg ttcctgcgca gcatggcgat ggacctgacg gtgatgtcgt
    11581 acccgaccta cgacgacctg ctcgactaca tggagggctc ggccgccgtc atcggcacca
    11641 tgatgctgcc gatcctgggc agctccgacc cggccgccgc ccgggagccc gcccgccagc
    11701 tcggcttcgc cttccagctc accaacttca tccgggacgt cgccgaggac ctcgaccggg
    11761 gccggaccta cctgcccgac gaggatctgg ccaagttcga cgtcacccgc gccgacctcg
    11821 tcgcggccaa ggccgccggt cgcaccacgc cgcgcatccg cgagctgatc gagtacgagg
    11881 tgacccgcgc gcaggcccac tacctcgccg ccgcgccggg catcccgctg ctcaaccccg
    11941 cctcgcaggc gtgcatgcgc accgcgtacg cgctctacgg cggcatcctg gacgaggtcg
    12001 ccgcgcagga ctacgacgtc ttcgtccgcc gggccctggt gccgcagcgg cgccggatgg
    12061 cggtggccgc gcgggcgctg ctcaccccgc ccggcacgcc ggttcaggtg cccggcccgg
    12121 cgctggaacc ggccctggcc ggatgaccgg ccggacggcg gtcgtgctgt tcacccgcga
    12181 cctgcgggtg cacgaccacc cggcgctggc ggccgcctgt tccgcgttcg agcgggtggt
    12241 gccgctctac gtgctcgacc cggagttgca gcagctctcg ccgaaccgca cccgcttcct
    12301 gcaccagagc ctggccgacc tgcgcgaggc gctgcgcaag cgcggcggcg acctggtgat
    12361 caggcgcggc gacccggtgg ccgagacggt gaagctggcc cggaaggtgg gcgccgaggg
    12421 cgtcgggctc tccgccgacg tgagccacta cgcccgccgc cgggaacgcc gcctgcgcgc
    12481 cgagtgcgac cggcaccgca tgttcctgcg gttgttcccc ggcctgacga tcgtcgagcc
    12541 gggcgcgctg cgcccgagcg gcggcgacca ctaccgcgtg ttcagcccct acttccgcgc
    12601 ctggcagggc gtgcgcctgc gggacgaact ggccgcgccg aagcgggtcc ggctgcccga
    12661 cggcgtcgac ccgggccgcc tgcccgaccc gccgaagggc gacagcccgg ccgccgccgt
    12721 gggcggggag aacgccgccc gccgccggct caccgcctgg ctgcccaccc tcgaccggta
    12781 cgacgacatc cacgacgaca tggccggcga cgagacctcc cggctcagcc cgtacctgcg
    12841 cttcggctgc gtctccccgc tggcggtggc gacccgggcc ggcgaccgcg acggcccgtt
    12901 cgtccggcag ctctgctggc gcgacttcta ccaccaggtc gtcgccggat tcccggacct
    12961 gtccacggcc gcctaccggc ggggcgcccg ggaggactgg cggtacgacg agcacgcgct
    13021 cgacgcctgg accgagggac ggaccggcat gccgatcgtg gacgccggca tgcgtcagat
    13081 gcgcgccgag ggctggatgc acaaccgggc ccgcctgatc accgccggct acctgaccaa
    13141 gcacctcggg ctggactggc ggcccggcct ggaagtcttc ttccggtggt tgctcgacgg
    13201 cgaccgggtc aacaactccg gcaactggca gtgggtggcc ggcaccggca acgacacccg
    13261 gccgtaccgc ggcttcaacc cggtacggca ggccgagcgc tacgaccccg acggcgcgta
    13321 cgtgcggcgg tgggtgccgg agctggaatc ggtggcgggc aaggcggtgc accagccgtg
    13381 gcggctgccc gacgctgtgc gtcgcacgct cgactacccg ccgccgctgg aggtgcccgg
    13441 cgccgacccg gtctggctcc gctgacgccc tccccctcgc cgcccgccgc ccgccgcccg
    13501 cgcacgagcg cgaacgtcac acgagcccaa cgtcgctggc ggcccgcgcg ggccgcagca
    13561 cggcgcccac gattactgcg ggtgactgca cctctagccc gcgcctatcc acctccgccg
    13621 actttgctct gcagccatat ccgcacccgt tgcggaacgt gaccggtgcg ggcctctcgc
    13681 ggatttcgga cctagcggaa atccgctgct caactcggtg ctgcgccaat gggtgcagag
    13741 caaagtcgga aaaggggaag ccaggcgcga ctgccggccg aatgcgctgc gtgacgacgc
    13801 gccggaatca cagaacgtga ctaaccgtca gaggcaggag tgcagcgcct cgaccagctc
    13861 ctccacccga tcgtggtcgg ccagccgggc ggtcgcgtac gcgaaggtgt agccccgctc
    13921 cgggtcggcc caggcgctgc tgccgccgat cccgcccatg ccccagctgc cgtccggctc
    13981 ccactgcatg ccgagcgtcc agtccaccgg ccggtccagc agcaggtccg gcccggaata
    14041 ctgcacccgc gtcgcctcgg cgaccagctc cgggctgaac agacgtaccc cgtccagggt
    14101 gccgctggcg agcaggcccg cgtacagccg ggcgagcccg gcggcggtgg cgtgcaggtt
    14161 caccgccggg atctcggcgg cccgccagag gtcgctgttc accatcgcga cgtcgcgccc
    14221 gccgggcggg ttgtccagcg cccgcgcccg caacgaaccc ggctcgccgc gcatcgcgtc
    14281 cggccaggcc ggatcggcgt acgacaggtc ggcgcaccgc cgccggtcgg tctcacccag
    14341 cccgaaggcc aggtccaggc gccacggacc ggcgatctcc tcggccagga accggcccac
    14401 cggccgcccg tccacccggc ggaccaactc gcccaccagg tgcccgtacg tccaggcgtg
    14461 ctcgcccgcg acggcgcccg ggtcccactc cggctcggcc gtcgccaggt cggcgcagag
    14521 caggccccag tcggcgatgg ccgcggcggg gcggggcacc gggaaggcgg gcagcccggc
    14581 ggtgtgggcg aggacctgcc ggacggtcgc cggggtgcgg aactccggcc agtacgccga
    14641 caccggcgtg tccaggtcga cccggccccg gtcgacgagc agcagtagac agagcgccac
    14701 caccggcttg ccggtcgagt agacgtccac gagcgtgtcc ggacgccacg cgcggtccgc
    14761 ccctgccatc ggtgcgaccg cactgggcgg gaccgccgcc gccgtgccgc ccatcagctc
    14821 gatcaccggt acgccgtcgt gccacaccgc gagcgacgcg ccggtctccc ggccggtgac
    14881 gaacaggtcg tggaagcagt cccggaccgg ggtgaagcgc gtgtgcatgc ggccacggta
    14941 ggcggtcgcg ttcgtgacga gcgcgggaat tcggggccgg tgcggtggcc ggtgtcccga
    15001 aggtacggaa tgcttgcgga atggcggagc cggaacaggt tgacgtagta gtggtcgggc
    15061 tcggcgtcgg cggcgaggag gtggccggac ggctcgccga ggccggcctc acagtggtcg
    15121 gcatcgaacg ggacctggtc ggcggcgagt gcccctactg ggggtgcgtg ccgagcaaga
    15181 tgatgatccg ggcggcgaac gcgctggccg aggcgcaccg ggtcaacgag ttggccgggt
    15241 ccgcccaggt gcggccggac tgggcgccgg tggcgaagcg gatccgcgcc gaggccaccg
    15301 acacctggga cgacaaggtg gcggtggacc gcttcaccgg caagggcggc cggttcgtcc
    15361 ggggcagcgg gcggctcgac ggcccgaacc gggtacgcgt cggcgaccag gtgttccagg
    15421 cccggtacgg cgtggtcctc ggcaccggca cccggccctc ggtcccgccg atcgacgggc
    15481 tggccgacac gccgtactgg acgaatcacc aggccatcga ggtggaggag ctgcccgcgt
    15541 cgctgctggt gctcggcggc ggcgcgatcg ggctggaact cgcgcaggtc ttcgcccggt
    15601 tcggcgtgcg ggtgacggtc atcgaggcgg ccgaccgggt gctcgccgtc gaggagccgg
    15661 aggcgtcagc gctcgccgcc gacgcgctgc gcgccgacgg ggtggagatc cacaccgggg
    15721 tcaaggccgg ccgggtcggc cacgacggcg gcgcgttcac cgtgtacgcc gacggcgccg
    15781 agttcaccgg cgagaagctg ctcgtggtga ccggccgcaa ggcgcacctg gaggagttgg
    15841 gcctggacac ggtcggggtg gacgccgggc agcgctacct gccggtgaac gaccggatgc
    15901 acgtcaccga ggggatctgg gcggtcggtg acctcaccgg cgagggcgcg ttcacccaca
    15961 tcgccatgta ccaggccggc atcgtggtgg ccgacgtcct cgaccacatg cggcgtacca
    16021 agggcggccc ggacgccagc ggcaccgcga gcgtggtcgg cggcgcggcc ggtgtggtca
    16081 gctcggtcgg cggcgcgatg agcgcgggcg ggtcgagcgt cgcgccgggc agcgtcccgg
    16141 tcgccgacta ccgggcgctg ccccgggtca cgttcaccga ccccgaggtc ggcgcggtcg
    16201 gcctcaccga gcagcaggcc cgcgagcgcg gcgtcaacgt ccaggtcgga tacgccgatc
    16261 tcacctcgtc ggcccggggc tggatccaca agaccggcaa cgccgggttc atcaagctgg
    16321 ttgccgacgc cgaccagggc gtgctcatcg gggccacctc ggccggaccg gccggcggcg
    16381 aggtgctctc cgcgctcgtc gtggcggtgc acgcggcggt gccgatcagc cagctccggc
    16441 acatgatcta cgcgtacccg acgttccacc gggccatctc cgacgcgctg cgcgcgctga
    16501 agtgacgcgt cagccggccg gcgcgccgtg ccggccggcc ccggcggcga accggccggc
    16561 gccgcgtacc ccgtccaccg ccagcgactc catgccgtag gccagctcgg tggccatcgc
    16621 ctccggctcc ggccgccccg tgccgtccag caccgccgcc cggtcgttgc gcaggcacgt
    16681 ctgcggcgac cgggcgatag cggcggccag ctcctcggcc gccgcgcggg ccgcacccgg
    16741 cgcgacgagc cggttgacca gacccatcgc gtacgcctcg tcggcgccga ccgggcgtcc
    16801 ggtgaggatc aggtccatcg cccggctctc gccgatcagc cggggcagcc ggaccgtccc
    16861 gccgtcgatc agcggtacgc cccaccggcg gcagaacacg ccgagcgtcg cgtccgactc
    16921 ggcgatacgc aggtcgcacc agagcgccag ctccagcccg cccgccaccg cgtacccgga
    16981 gatcgccgcg atcaccggct tggacagccg catccgcgtg gggcccatcg gtccgtcccc
    17041 ctcgggctcg acgcggttgc cgcgcggcgt gccgacggcc ttcagatcgg cgccggagca
    17101 gaacgtgccg cccgcgcccc agagcaccgc gaccgccgcg tccgggtcgg cgtcgaatgc
    17161 gcggaacgcg tcggccagcg ctcgtgcggt cggcccgtcc acggcgttac gggcctcggg
    17221 ccggtccagg atcacagtgg tcacggcacc ggcgtgctcg acgcgtaccc ccatgggctc
    17281 agcatgcccg cgacggcgct gccgtggcta cgccctattt gatcgagccg ggtcgggtca
    17341 gccagcgcat cggctggccg gtgacggcgc cgacctggtc gaagtcccgg tcgtagtgca
    17401 gcagcgagag accgtggtac tcggcggtgg cggcgatgag caggtcgacc gcgcccgccg
    17461 agcggtgcgt cccccgcacg gtcagctcgc cctggatctc ggcggcgcgt tcgtagatcc
    17521 ggtccggcat gaccacccag ccgaaggcgg cccggagctg ctcggtcagg cgcgtccggt
    17581 cggcgaccga ccgggcggtg tagaggaatt ccagctcgac cagcgggcac acggcgagca
    17641 gacccgctgt cacctgctgt tcccagcgcg ccagcacgtc gggatcacgc aggagccgga
    17701 cgagggcgct ggtgtcgatc aggtagtcgg ccagcttcac gagcggtagg cacccttgtc
    17761 gagcagttcg tcgaagtcac cggcctgccc gcgttcggcc agctccgcca gtgcccgggc
    17821 gcggcgcagt ctcgccgcgc cctcgcggag agcgacgttc accgtgtcct tcttggtctt
    17881 cgtgccgaac gcctcggcgg catccgccag cgcctcgtcg tcgacgtcca ccaggatctt
    17941 ggtcatcgcg gctccctata tacgaccagc cgcccgagta tatccagcgc ggaggctgtg
    18001 cgagggaatt ccggggcgtc cggtttgggg gctctcctgc cgggaagtcg gaacgggtgc
    18061 gcgaactact gacgaagatc gaacaggcca ccggtctcga ccgggtgggt gaccggttgc
    18121 agcgcgccgt ccagggcacg ctgcgttccc agcgggtacg cgacgcgctg cacggcgtgt
    18181 ggctcggcca tccgctgcac cccgcgatgg tgcaggtgcc ggtcggcgcg tggatctccg
    18241 ccgccgtggt ggacctgctg cccggccaac gccgggccgc caccgcgctg gtgggcctcg
    18301 gtacggtcag cgcgctgccc gcagcggtcg ccgggctcaa cgactgggcc acgctctccc
    18361 gcgaccagcg ccggatcggc ctggtgcacg ccgccgccaa cacggtcggc ctggcgctgt
    18421 acgccggctc gctggcggcc cgcctcaacg ggcggcacgg cctcggccgg gcgctgtcct
    18481 acctcggtct gtccgccgcc agcggtggcg cgtacctggg tgggcacctc gcgtacaagc
    18541 agggcgccca ggccagccag agcgtctccg agctgcacct gatcagcgac ggctggcacc
    18601 gggtcggcga cctgggcagc ctgccccggc acgaactggt caccaagaag atcgacgacg
    18661 tctcggtgat cctctaccgg gacggcgacg acgtcacggt gatgctggag cgctgcccgc
    18721 accagagcgg cccgctcggc gagggcactg tggagcagat cgacggccac gcctgcgtgg
    18781 tctgcccctg gcacggcagc gcgttccggc tcaacggcgg cgaggtggtg cacggcccgg
    18841 ccgcgaacga ccagatcgtg ctccccaccc gcgtggtgtc cggccaggtc gaggcccggc
    18901 tgccctgact cagtcccgcc ggtgccgccc gctggaaccc gcgcgggcgg gcaccggccg
    18961 cttgcgcaac cccagcagcg cgccgatctg cgcgcccacg atgctcgcga ccgccagcac
    19021 cgccgagatg gcgagcggac ggttgatgcc ctcctcggcg gtgggccggg acgcgcccgc
    19081 cgacatggcc ggcggctgac cgaccggcgc ctccacggtg ggcgtcgcgt cccgcggggt
    19141 gggcttcggc ttcgccttcg gcgcgcttga cgacgcgccg ccgccacccg gcttgaccgg
    19201 tgcggtctgg gccggtttgg tgaccaccag ccgtccggtg gcgtgccgcc gggcgccgga
    19261 gtccgtcgcg ccgtccggca gcgtgatgag ctggccgggg cggatccggt ccgggtcggc
    19321 gagccggttc atccgggcca gctccttgta cctgtcgaag tcgtccaggt agcggtcggc
    19381 cacctcgccc aggtagtcgc ccttcgccac ccggtacacg gccgggtcgt ccgccttcga
    19441 cgcgaccggg gccggcggcg cgacccggct cggcgcggtg acggcagaag cggcgaccgc
    19501 cggctgcggg gcggtcagcg cggcggcgct cgccgcggcc gggctcgcgg ccaggatcag
    19561 cgcgaccgaa ccgacgagcg cggctgcggc cttctgctgg cggtgcatgc cgggcagctt
    19621 cggcgccggc cggcgtaccg cagccgcgag caactccacc acgacggaga acgtgaacgt
    19681 ggcccagccg aaccagccca ccaccgccag cgcgcgcagg aacagttgac cgtcgtcgcg
    19741 gctggtcagc gtcgtaccga tctcggcgaa cgtgggcagg ttatccggca gcgggttgcc
    19801 ggcgaacgcc agcagcgcga ccggcccgcc ggccagcacg ccgacgagca cgacgagggc
    19861 gccgaggccg gtgagaacct ggccggcgcg gcggacgggg gagcgtcggg gtgcgcccat
    19921 ggcggccttc ccttcctacg gtgggccggt gagcgcccga gcggtggcct caccggtgac
    19981 ggtggcggtg ttctgcacgc cgaacagact cagcaggtcc cggctgtagg tgatctgcac
    20041 gctcacccgg atctgggtct cggcgccgac cacggggaag tcgacctcgt ggtcctggac
    20101 gccgcccgcc gcgtcgaggt aggcggcgac agcggcgcgg gcggcgacct ggtcgatctg
    20161 cttcgggccg ccctcgatgg cccgcgcgcg gtcgatcatc tggccgccgg cgcgggccgc
    20221 ctcggcggcc aggttgtccg cgcgttggag cgtgcgcagc tggccggcgc cgtcgtaggc
    20281 gaggctgatg atcgccagta cgccggtcat cgccacggcc aggaagagac tcacccggcc
    20341 gttctccgcc gcgcgccgcc cggtcatccg cgactccggt aggtgtccag cggcgaggtg
    20401 aacctcgccg agacggtctt gccgccgggc acgccgggca ggccgggcgc gctcaggtcg
    20461 tcgaaggaga cggtgcaggt cacagtgacc gtcacggtcg ccggcacgcc tgcggcgctt
    20521 gcgtacgcgg cggcgaagct cgtcgtcgta ccggccaccg agcccgcgag gtcgatctgg
    20581 ggcggaccgg tgcagttcag tcccgcccag ccgagctggt cctgggccgc ctcctcggcg
    20641 gcctccgcgc cgtcgtcggc gttgcgggcg agcgaggcgg cccgggcggc gtcgtgcgcg
    20701 gccgactcca ccgcctcgtc cgcgatcgcg gtccgcccgg cgaccccggc cagcaccatc
    20761 agcccgatga aggcgggcgc gagcaccgcc acctcgatcg agacggaacc ccggtcccgc
    20821 cgcggcccgg cgctcatccg gtggtccagc gttcggccgg gccgtgcgcg gtctgcgtga
    20881 ccgcgaacga gacacccggg atgaccgaca gggagcgccc ctgcaccgtg caggtgacgg
    20941 cggtggcggt ctcgacgcac gtcgggccgg tctgctccca gccgaccagc cagtccccgg
    21001 actgctgcag gaagctgatc gcccgctccc ggccggcgtc cggcccggcg tcgatcgtgc
    21061 gctgggcgtt cacaccggtc tgcgcggcgt tgagcgccgt ggaccgggcc acgaaccaga
    21121 cggcgacctg gatcgagccg aacagcatca ccaggatcac cggcatcacc acggccagct
    21181 cgaccggatt ggcgccccgc tcgccctcgg ccagacgggc gcgcagagca gcggcgatcc
    21241 gccccggacc gggcggaccg gcgggccggc cggcgggcgc cggccggctc cggaccgtac
    21301 gggcggggcg gggcatcacg gggcctgcgg cgccgtgttg ttcgggatgg cgttcatcca
    21361 gttgttcgcc ttggccaggg cgagcccggt gaccgccatg gccaccgcga ccaggccgaa
    21421 gatgatcacc gcggtcggca ccgggctgtc gccgcgctcg gagtcccggc gcagctcggc
    21481 gaggcgggtg ctcaccgcca cgtacaggta ggcgtagagg tgcatggtcg tctccttctc
    21541 gatggggttc acagacgggc gaggaacgga tagacggcga agccgagcag gacgaacacc
    21601 agcagcgagc cggggatgtc caacttgctg gtgaccccct cggcccgggc caggttgtcg
    21661 gtacggatct ggtcgcgcag cgagtcggca cgggaccgca acgtctcgtg cacctgggcg
    21721 ccctcgctgc cggaggagcg catgatcgcg cccacatcgc ccagctccgg gatgccgatc
    21781 cggtcggcca gctcctgcaa ctcgtcccag ggcgagtgca tctggagctg ggcgagccgc
    21841 agcgcctccc ggatccggtc gaagacccag ccgtcgcaga ccgccgccgc gcgttccagc
    21901 gactgcaccg ggccgtgcgc ggcggacagc tgcagcgcca ccaggtcgag gtaggtgcag
    21961 accgcctgcc ggaactcgtc ccgggcggcg tcggccttgg cgaggaccga gcggtgcgcg
    22021 agcagtccgg cgccgagcgc cagacccagg ctggccacca ccggcacggc cagcggcagc
    22081 gccaccccgc cgacgaagag caccgccgag gcgaccgccg gggtggcgaa cccgacgagc
    22141 gcggag
//
