LOCUS       NZ_CP118233            20951 bp    DNA     circular CON 13-JUL-2024
DEFINITION  Micromonospora chalcea strain 1K05785M01 chromosome, complete
            genome.
ACCESSION   NZ_CP118233
VERSION     NZ_CP118233.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora chalcea
  ORGANISM  Micromonospora chalcea
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Study on the Growth Characteristics and Drug Resistance Related
            Proteins of Micromonospora chalcea MCCC 1K05785
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2023) Tianjin University, Tianjin University,
            Weijinlu Nub92, Tianjin, Tianjin 300072, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2022
            Assembly Method                   :: CLC NGS Cell v. 5.29
            Assembly Name                     :: TJU-micro-1.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028768405.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 23:01:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,224
            CDSs (total)                      :: 6,161
            Genes (coding)                    :: 6,110
            CDSs (with protein)               :: 6,110
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 51
            CDSs (without protein)            :: 51
            Pseudo Genes (ambiguous residues) :: 0 of 51
            Pseudo Genes (frameshifted)       :: 16 of 51
            Pseudo Genes (incomplete)         :: 40 of 51
            Pseudo Genes (internal stop)      :: 2 of 51
            Pseudo Genes (multiple problems)  :: 7 of 51
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:37:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2895211
            Orig. end                         :: 2916162
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP118233.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20951
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="17"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20951
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20951
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10951](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10951
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(7..420)
                     /db_xref="GeneID:91356934"
                     /gene="hisI"
                     /locus_tag="PVK74_RS12245"
                     /old_locus_tag="PVK74_12245"
     CDS             complement(7..420)
                     /EC_number="3.5.4.19"
                     /GO_function="GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356934"
                     /gene="hisI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007072124.1"
                     /locus_tag="PVK74_RS12245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12245"
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="WP_043331113.1"
                     /transl_table=11
                     /translation="MPAPDAPLTGAPSPGPARPSRLDPAIAAKLRRTPDGLVAAVVRAH
                     DTGEVLMVAWMDDEALHRTLTTGRATYWSRSRGEYWVKGATSGNHQYVRSVALDCDGDA
                     LLVSVEQVGAACHTGQRTCFFTDLPVSSPEETP"
     misc_feature    537..551
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.07"
                     /tool="antismash"
     gene            complement(<649..1248)
                     /db_xref="GeneID:91356935"
                     /locus_tag="PVK74_RS12250"
                     /old_locus_tag="PVK74_12250"
                     /pseudo=""
     CDS             complement(<649..1248)
                     /codon_start=1
                     /db_xref="GeneID:91356935"
                     /inference="COORDINATES: protein motif:HMM:NF037778.4"
                     /locus_tag="PVK74_RS12250"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12250"
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLRGSHARRAATEHSDVDVDVLVAADEPRATGGPRPVTSRRGTPY
                     AARRAYLTEFGGRLVHVSVAARDVRSWVRRLGQPADWAFGLPVTAPARLLWAVPEWRRR
                     IDLPVLCQPADEPRLEELIATLGKVAAARLAGDPAGVRLAAADLARLCPSVLRPANPSV
                     RVVSRRAALTAALDLPVAPAGYRDDMLLCLGLRPGDP"
     gene            complement(1400..1789)
                     /db_xref="GeneID:91356936"
                     /locus_tag="PVK74_RS12255"
                     /old_locus_tag="PVK74_12255"
     CDS             complement(1400..1789)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356936"
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287558.1"
                     /locus_tag="PVK74_RS12255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12255"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_051611426.1"
                     /transl_table=11
                     /translation="MDISTREMSLTVGEAAERVGLTTYTLRWYEQEGLVGRVGRDSSGR
                     RRYTESDVNWLFLLTRLRRTGMPVRDMRRYAELARHGDSTLGARRALFEAHRARVLARM
                     AELEEDLKVLEYKIDAYRRAEEESG"
     gene            1900..2622
                     /db_xref="GeneID:91356937"
                     /locus_tag="PVK74_RS12260"
                     /old_locus_tag="PVK74_12260"
     CDS             1900..2622
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356937"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287559.1"
                     /locus_tag="PVK74_RS12260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12260"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_043329517.1"
                     /transl_table=11
                     /translation="MDDAVSVRELVVDRGGRRVLHGITCGVPRGTVTGLLGPSGSGKTT
                     LMRAVVGVQTVGSGAVDVLGRPAGSADLRRRVGYLTQAPSVYADLTVRENARYFAVLQG
                     RGRAEADRAVTDVGLGKAADQLVGTLSGGQRSRASLACALVGEPELVVLDEPTVGQDPV
                     LRADLWARFHAMAAAGTTLLVSSHVMDEAARCDRLLLIREGRLVADDTPAAVRAATGTD
                     DLEEAFLRLIRDAEGEAR"
     gene            2619..3374
                     /db_xref="GeneID:91356938"
                     /locus_tag="PVK74_RS12265"
                     /old_locus_tag="PVK74_12265"
     CDS             2619..3374
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356938"
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014389.1"
                     /locus_tag="PVK74_RS12265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12265"
                     /product="ABC transporter permease"
                     /protein_id="WP_166456895.1"
                     /transl_table=11
                     /translation="MNGRILAATTGRILRQLRHDRRTVALLVVVPSVLLTLVYFMYVDQ
                     PAPPGAPSTFDRVALIMLGFFPFIIMFLVTSIAMLRERTTGTLERLLTTPLGKLDLLFG
                     YGIAFGLAGVLQSTVASVVAYRVFGLETAGSAWLVVLIAGVNAVLAVALGLFCSAFART
                     EFQAVQFMPVVVAPQLLLCGLFVPRDQMAGWLQAVSDALPLSYAVEALQEVGAHAEPTG
                     TMWRDVAIVTGAAVAALVLAAATLRRRSG"
     gene            3371..3967
                     /db_xref="GeneID:91356939"
                     /locus_tag="PVK74_RS12270"
                     /old_locus_tag="PVK74_12270"
     CDS             3371..3967
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356939"
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287561.1"
                     /locus_tag="PVK74_RS12270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12270"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_030500283.1"
                     /transl_table=11
                     /translation="MNARRTGRRPGTPDTREAILAAAREAFAERGFDAASIRAIAAAAG
                     VDPALVHHYFGGKEELFRAATAFPADPGRLLPAVLAGGPDALGERMVRVFLEVWDSPTG
                     TAAVALLRSAVSNDWTARLLREFLVTQVLRRVLDQLDVDPAQRALRGGLVATQLAGLAM
                     MRYVLRLDAVATAEPATLVAAVGPTVQRYLTGDIT"
     gene            complement(3979..4713)
                     /db_xref="GeneID:91356940"
                     /locus_tag="PVK74_RS12275"
                     /old_locus_tag="PVK74_12275"
     CDS             complement(3979..4713)
                     /codon_start=1
                     /db_xref="GeneID:91356940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785219.1"
                     /locus_tag="PVK74_RS12275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12275"
                     /product="DUF2470 domain-containing protein"
                     /protein_id="WP_043329514.1"
                     /transl_table=11
                     /translation="MRPSPAEIVRTLVAGRLPALVHLARHPGPHQVRHAVDPDGRVLLL
                     VPVVSDLAAALVPPAGDADVAAVLDVLDLPPAAGAPSLGRAWVSGWATRLNGDEARDAA
                     VDFAATDPVADLLDVGSRFHLHRFEVAEARWERAGRVRRIDPEAFAEAEPDPLHPVEAA
                     LLADLADHHAEQVGDYLRRRLDLPGDQIPRVVRIDRYGLLVAHGRPGATRRARLAFPRP
                     VADVAELSRLLHPMLCPRAAAA"
     misc_feature    4732..4750
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: strong, score: 32.19"
                     /tool="antismash"
     gene            4781..5389
                     /db_xref="GeneID:91356941"
                     /gene="rpsD"
                     /locus_tag="PVK74_RS12280"
                     /old_locus_tag="PVK74_12280"
     CDS             4781..5389
                     /GO_component="GO:0015935 - small ribosomal subunit
                     [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_function="GO:0019843 - rRNA binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356941"
                     /gene="rpsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012015561.1"
                     /locus_tag="PVK74_RS12280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12280"
                     /product="30S ribosomal protein S4"
                     /protein_id="WP_064445248.1"
                     /transl_table=11
                     /translation="MNHPRPKARLSRALGIPLTRKCVRYFERRPYPPGVHGRSRRTTSD
                     YQVRLLEKQRLRHQYNVSEAQLRRLFDEAARAAGKTGDTLVALLERRLDAVVLRAGLAR
                     SIYQARQLVGHGHITVDGRKVDRPSYRLRPGQVVGVRERSRTLPPFQLAAAGAHADAQP
                     RPYLSAQPAQLRATLVREPARHEVPVVCDEQLVVEFYSR"
     gene            complement(5394..7184)
                     /db_xref="GeneID:91356942"
                     /locus_tag="PVK74_RS12285"
                     /old_locus_tag="PVK74_12285"
     CDS             complement(5394..7184)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356942"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475811.1"
                     /locus_tag="PVK74_RS12285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12285"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_043329513.1"
                     /transl_table=11
                     /translation="MSATTAEADRSTETTESTWQTLRRGLALSPELRTGLAGTLALALV
                     YMVGRVAVPVAVQRGIDHGIVGGLDLNVISLTVAITAGVLVVTTACGYLMMRRLFTVSE
                     TALAGVRTRAFRHVHDLSMLHQQSERRGSLVSRVTSDVDQITQFLQWGGVILIVNLGQL
                     LVTTAVMLAYSWQLTLVVLVAFAPAVLVIRQLQRRLAGAYGLVRQRTGTLLGAIGESVV
                     GAPVIRAYGIAGRTARRLDTAIDGQRVAQQRAIRISIMGSSVGELAAGLALAGVVVVGV
                     SLGVDRTLSVGQLTAFLFLVTLFIQPVQIATEVLNEAQNAIAGWRRVLDVLDVSPDVAD
                     PGEQGRELPPGPLDARFAGVTFAYPGGPPVLHDVTLDIPAKSRVAVVGETGSGKTTFAK
                     LLTRLMDPTEGAVLLSGVDLRQVRFDSLRSRVVMVPQDGFLFDATVGENVRFARPDLTD
                     ERLTAAFGELGLADWLDGLPSGLDTPVGERGEALSVGERQLVALARAYVADPDLLVLDE
                     ATSAVDPATEVRLQRTLDAVTRGRTTLAIAHRLSTAQAADEVIVVDRGRIVQRGPHDEL
                     VRDTDSVYALLYASWLEQTR"
     gene            complement(7181..9049)
                     /db_xref="GeneID:91356943"
                     /locus_tag="PVK74_RS12290"
                     /old_locus_tag="PVK74_12290"
     CDS             complement(7181..9049)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356943"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018832748.1"
                     /locus_tag="PVK74_RS12290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12290"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_181373759.1"
                     /transl_table=11
                     /translation="MASGTSRDVLGRGLRVLGRAIREQPRIFAVAVSGSVLFGLLVIAS
                     AYVVGGVVGKVVVPAVERGEVARGTLALAAAALLGISVLRVVGIFGRRLGAGYMQYRLQ
                     AAYRRRVTRRYLELPLAWHHRNSTGTLLSNANSDVEAAWYPIAPLPFAVGTLVMLVGAV
                     ASLFVTDWALALVGLAVFPALFALNVVYSRRMAPRQARAQRLRAEVSGIAHESFDGALV
                     VKTMGREAQETARFAARAGELRDALISVGRLRGVFDPMLETLPSLGTLAVLVVGAIRLR
                     QGAITVSELVSVAFLFTVLAFPVRAIGWVLAELPRSVAGWDRVRRVLDATGEMPYGTRT
                     LDPATRTPATLAFHDVHFAYEPAEAHLPGAQVLGEVTFTVPAGKTVALVGPTGSGKSTI
                     ASLAVRLVDPGAGRVTLDGVDVRELTAASLAGNVALVAQVPFVFDDTVRANIALDRAGI
                     GDDEVWAALRLAEADGFVAALPDGLDTMVGERGTSLSGGQRQRLTLARALAGRPRLLVL
                     DDATSAVDPRVEAAILAGLRAPADGGAPASILVVAYRRATIALADEVIYVEQGRVVARG
                     AHTELLATVPGYADLVTAYEQAEQEREQKQTYDEVTPLASGLEVER"
     misc_feature    complement(9144..9160)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.67"
                     /tool="antismash"
     gene            9243..9872
                     /db_xref="GeneID:91356944"
                     /locus_tag="PVK74_RS12295"
                     /old_locus_tag="PVK74_12295"
     CDS             9243..9872
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183502.1"
                     /locus_tag="PVK74_RS12295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12295"
                     /product="TIGR03085 family metal-binding protein"
                     /protein_id="WP_030500278.1"
                     /transl_table=11
                     /translation="MPRYARTEREALADLMLELGPDAPTVNEGWTTRDLAAHLLVRERR
                     PDAAGGILLPPLRGYGESVRRRIAAGPYADLIARVRRPPVWSPVSNPLTDEIANGMEFF
                     IHHEDVRRARPGWQPRDLPAGQQAVLWKRVALLARMALRRFPAEVLVQAPGHGELRAGG
                     GGERLRLVGAPGELVLFLTGRQRVARVQVDGPAERAERLRTAELGL"
     misc_feature    complement(9928..9939)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.1"
                     /tool="antismash"
     gene            10001..10951
                     /db_xref="GeneID:91356945"
                     /locus_tag="PVK74_RS12300"
                     /old_locus_tag="PVK74_12300"
     CDS             10001..10951
                     /codon_start=1
                     /db_xref="GeneID:91356945"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287567.1"
                     /locus_tag="PVK74_RS12300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12300"
                     /product="terpene synthase"
                     /protein_id="WP_043331108.1"
                     /sec_met_domain="T1TS (E-value: 3.4e-75, bitscore: 252.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDFALSALHEPPFPSRCHPAADEVAAQSVAWVRGFGLVKTQAGL
                     LRLAGAHASELAGRACPEASPAGLRLLTDLINWLFVVDDACDDDGLGAAPTVLAPTLAA
                     LLEVLDRHGDPDAPAPTDAGPMGLALHDLCRRARGRGRPAHLMRLVSQLREYLLALLWE
                     AANRERRRVPGVAEYVQMRRHTGGVRPSFTVTDLARPSLPRADQRATPALTALDALATD
                     LVCWCNDVFSYGKERGVTPDAHNLVTTIAGETGQDESAALNAAANRFNAALASYAERDA
                     ALSAGADEGMRAFLDTRRDWIRATYDWSRAASRYA"
     misc_feature    complement(11046..11061)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.38"
                     /tool="antismash"
     gene            11091..12917
                     /db_xref="GeneID:91356946"
                     /locus_tag="PVK74_RS12305"
                     /old_locus_tag="PVK74_12305"
     CDS             11091..12917
                     /NRPS_PKS="Domain: AMP-binding (14-471). E-value: 4.3e-88.
                     Score: 287.6. Matches aSDomain:
                     nrpspksdomains_PVK74_RS12305_AMP-binding.1"
                     /codon_start=1
                     /db_xref="GeneID:91356946"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475807.1"
                     /locus_tag="PVK74_RS12305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12305"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_043329509.1"
                     /sec_met_domain="AMP-binding (E-value: 9.3e-86, bitscore:
                     286.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALDVPYRSVPDMFLKRVADSPDRQAFAHPAPDDSGPVWLTWEQV
                     GQRAKAIAAGLHGLGVGLENPVAILANTRLEWVLADFGIMCAGGATTTVYPTTEPDDAV
                     YIIADSGSKVLFAENPAQAAKIAGADLPALTHVVLFDGAPDPAAAVPQLTLAELEERGA
                     AALSAEPDLIDMLVAGIGPDHLATLIYTSGTTGRPKGVELLHGGWCWEGVAQAELGLLR
                     TDDLQYLWLPLSHSFGKTLLCGATHVGLPTYVDGRVDKLVDLLGVIRPTLMCGAPRVFE
                     KVYNKAVTTAQGAGGAKAKIFAWGVEVGKEKVALEQAGKPVPAGLRMKYALAEKLVFSK
                     LQARLGGRMRVLVSGAAPLSKEIATFFAAANLPISEGYGLTETSAGAFVNPPDGLKIGS
                     VGRAMGDLECRIDTDGEILMRGKPVMRGYHNLPEETAAAFTEDGFFRSGDIGTLDDDGY
                     LRITDRKKDLVKTSGGKYVAPSHIEGMFKAVCPYTSQAVVIGQARNYCTMLVTLDPDAI
                     KGWAAGTPLEGSDYTTIVTSPQAREMVEGYVAELNAKLNRWETIKKVTILPRDLTIEDG
                     EVTPSLKIKRRSVETNFSSEIDKMYEGTLAEL"
     aSDomain        11133..12503
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PVK74_RS12305_AMP-binding.1"
                     /evalue="4.30E-88"
                     /label="PVK74_RS12305_AMP-binding.1"
                     /locus_tag="PVK74_RS12305"
                     /protein_end="471"
                     /protein_start="14"
                     /score="287.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LKRVADSPDRQAFAHPAPDDSGPVWLTWEQVGQRAKAIAAGLHGL
                     GVGLENPVAILANTRLEWVLADFGIMCAGGATTTVYPTTEPDDAVYIIADSGSKVLFAE
                     NPAQAAKIAGADLPALTHVVLFDGAPDPAAAVPQLTLAELEERGAAALSAEPDLIDMLV
                     AGIGPDHLATLIYTSGTTGRPKGVELLHGGWCWEGVAQAELGLLRTDDLQYLWLPLSHS
                     FGKTLLCGATHVGLPTYVDGRVDKLVDLLGVIRPTLMCGAPRVFEKVYNKAVTTAQGAG
                     GAKAKIFAWGVEVGKEKVALEQAGKPVPAGLRMKYALAEKLVFSKLQARLGGRMRVLVS
                     GAAPLSKEIATFFAAANLPISEGYGLTETSAGAFVNPPDGLKIGSVGRAMGDLECRIDT
                     DGEILMRGKPVMRGYHNLPEETAAAFTEDGFFRSGDIGTLDDDGYLRITDRKKDLVKT"
     CDS_motif       11646..11705
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PVK74_RS12305_0001"
                     /evalue="2.20E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="PVK74_RS12305"
                     /protein_end="205"
                     /protein_start="185"
                     /score="23.3"
                     /tool="antismash"
                     /translation="ATLIYTSGTTGRPKGVELLH"
     CDS_motif       12333..12407
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PVK74_RS12305_0002"
                     /evalue="1.10E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="PVK74_RS12305"
                     /protein_end="439"
                     /protein_start="414"
                     /score="24.2"
                     /tool="antismash"
                     /translation="GEILMRGKPVMRGYHNLPEETAAAF"
     gene            complement(12989..14296)
                     /db_xref="GeneID:91356947"
                     /locus_tag="PVK74_RS12310"
                     /old_locus_tag="PVK74_12310"
     CDS             complement(12989..14296)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183503.1"
                     /locus_tag="PVK74_RS12310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12310"
                     /product="low temperature requirement protein A"
                     /protein_id="WP_181373758.1"
                     /transl_table=11
                     /translation="MGDGDAVRWSWAVRRSAPGSRTTRLELFYDLVFVFAFLSVTTLTA
                     SVLTPANLYRFLLVLALLWWSWTGFARMGNAFRADQGMLPLIGVVTVAATFLLVLSTPS
                     AFANSGGWLPGPLVFAACYFVIRTAQLTVFAWADRADPARRRGLRMRFLAPTVATALLV
                     VAGTLPGRLPQERFAVGLQLALWTLALLVEYVAGTVLGQQWWVVLSAGHWAERHALIVL
                     VALGESIIALGLGPKRGLPLTGPVAIAALLGITVVAALWWAYFDTLAFAMEQVLHQARD
                     RATRLRLARTAYTFLHLPIVAGIILYALGLKDLLAEAADPHTPAWGLPLGDFWGAILFG
                     GVALHLLGVAGCWWVALREIHWRLLTTVGALTAVAPFVFRVPELVALIVLAVVTGAGVA
                     WETRGENGHRRRVRQLALEEQIAAEAEQSRWRQQHL"
     gene            complement(14369..15820)
                     /db_xref="GeneID:91356948"
                     /locus_tag="PVK74_RS12315"
                     /old_locus_tag="PVK74_12315"
     CDS             complement(14369..15820)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (111-461). E-value:
                     1.6e-30. Score: 98.3. Matches aSDomain:
                     nrpspksdomains_PVK74_RS12315_Aminotran_1_2.1"
                     /codon_start=1
                     /db_xref="GeneID:91356948"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014395.1"
                     /locus_tag="PVK74_RS12315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12315"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_064445245.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.6e-28, bitscore:
                     98.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSQVRGVQLARLLGQWHALPGRRRSPDYAALAGAVRGLLADGRL
                     PLGVRLPAERELAEALRISRTTVTAAYRELRESGHLASRRGAGSWTMLPGGHRVASTGL
                     WTPLDDRDMIDLGVAALSAPPQLVPAARAAAEDLPRYLGGAGYHPTGIIELREAVARGY
                     TERGLPTSPEQIMVTSGTQHALDLVLRLALSPGGAVLVESPTYPNALAALAARRARIAT
                     HGLSDEGWDAELLLGSIRQTRPKLAYVIPEFHNPTGHLMAADLRERLVGAAHAAGTDLV
                     VDESFVDLPLDGTPLPPPVAVFDRHSRVISIGGMSKPYWGGLRIGWVRASAPQVQRLAA
                     ARVGVDMASPVLDQLVAVHLLAEAPAIVAARRAQLAAQRDALVAALAEQLPDWRVTPPR
                     GGVTLWAELDGPISSALARAAEEVGVRLAPGPRFGLDGTLERFLRLPFTLPAEELVEAV
                     GRLAAVRYDLDRTSRPQWREPSVIA"
     aSDomain        complement(14438..15487)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PVK74_RS12315_Aminotran_1_2.1"
                     /evalue="1.60E-30"
                     /label="PVK74_RS12315_Aminotran_1_2.1"
                     /locus_tag="PVK74_RS12315"
                     /protein_end="461"
                     /protein_start="111"
                     /score="98.3"
                     /tool="antismash"
                     /translation="DMIDLGVAALSAPPQLVPAARAAAEDLPRYLGGAGYHPTGIIELR
                     EAVARGYTERGLPTSPEQIMVTSGTQHALDLVLRLALSPGGAVLVESPTYPNALAALAA
                     RRARIATHGLSDEGWDAELLLGSIRQTRPKLAYVIPEFHNPTGHLMAADLRERLVGAAH
                     AAGTDLVVDESFVDLPLDGTPLPPPVAVFDRHSRVISIGGMSKPYWGGLRIGWVRASAP
                     QVQRLAAARVGVDMASPVLDQLVAVHLLAEAPAIVAARRAQLAAQRDALVAALAEQLPD
                     WRVTPPRGGVTLWAELDGPISSALARAAEEVGVRLAPGPRFGLDGTLERFLRLPFTLPA
                     EELVEAVGRL"
     gene            15880..16515
                     /db_xref="GeneID:91356949"
                     /locus_tag="PVK74_RS12320"
                     /old_locus_tag="PVK74_12320"
     CDS             15880..16515
                     /codon_start=1
                     /db_xref="GeneID:91356949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785228.1"
                     /locus_tag="PVK74_RS12320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12320"
                     /product="membrane protein"
                     /protein_id="WP_043329506.1"
                     /transl_table=11
                     /translation="MAPLGNLGHRSARRLTQLYAGLVLYGLSMALMIRSELGLDPWDVF
                     HQGLARQTGLSFGTVTIAVGALVLLLWIPLRQRPGLGTVSNVVVIGLVVDATLAVLPPG
                     EGMPARAAMLVAGIVANGAATGLYLGAGLGPGPRDGLMTGFVARHPRFSVRLVRTSIEV
                     TVLALGWLLGGTVGLGTVAYALTIGPLAQFFIPVFALPARPASGAYAT"
     gene            16632..17093
                     /db_xref="GeneID:91356950"
                     /locus_tag="PVK74_RS12325"
                     /old_locus_tag="PVK74_12325"
     CDS             16632..17093
                     /codon_start=1
                     /db_xref="GeneID:91356950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018804515.1"
                     /locus_tag="PVK74_RS12325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12325"
                     /product="hypothetical protein"
                     /protein_id="WP_043329504.1"
                     /transl_table=11
                     /translation="MGENGWRWSDAWIFVALVIASGAGRHRRSASTRRPEGVRLADVLS
                     TADHLNQAIPERHEVEGAVRRLVGAGLVSVADGWFRVTPDGERLWRTRPSAGLGTTVDT
                     VQGVLTRRHPPGESEWQLDEDDHAAAVQEYVVRSIPMPRRSPEGHSGRQ"
     gene            complement(17101..17868)
                     /db_xref="GeneID:91356951"
                     /gene="hisF"
                     /locus_tag="PVK74_RS12330"
                     /old_locus_tag="PVK74_12330"
     CDS             complement(17101..17868)
                     /EC_number="4.3.2.10"
                     /GO_function="GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356951"
                     /gene="hisF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019900882.1"
                     /locus_tag="PVK74_RS12330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12330"
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="WP_043329502.1"
                     /transl_table=11
                     /translation="MTVAVRVIPCLDVDAGRVVKGVNFLDLRDAGDPVELAAAYDRAGA
                     DELTFLDVTASSSDRGTMLDVVRRTAESVFIPLTVGGGVRQVADVDTLLRAGADKVGVN
                     TAAIARPELIAEIADRFGSQVLVLSLDVRRAPDGTTPSGFEVTTHGGRRGTGLDAVEWA
                     ARGAELGAGEILLNSMDADGTKAGFDLPLIQAVREVVDVPVIASGGAGEVAHFPPAVGA
                     GADAVLAASVFHFGELTVGEVKDALRGAGHPVR"
     gene            complement(17955..18947)
                     /db_xref="GeneID:91356952"
                     /locus_tag="PVK74_RS12335"
                     /old_locus_tag="PVK74_12335"
     CDS             complement(17955..18947)
                     /NRPS_PKS="Domain: PKS_ER (19-328). E-value: 4.9e-21.
                     Score: 67.1. Matches aSDomain:
                     nrpspksdomains_PVK74_RS12335_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GeneID:91356952"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785231.1"
                     /locus_tag="PVK74_RS12335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12335"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_274479273.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 4.3e-22, bitscore:
                     77.0, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNREIHLASRPQGWPTAENFRLVTTEVPTPGPGQVVVRNRFMSVD
                     PYMRGRMNDVKSYVPPFALDAPLDGGAIGEVVAGEAGGVKPGDTVLHGLGWREYALVDA
                     KGARKIDPDLAPVTAHLGVLGMTGLTAYAGLLDVAAMKPGETVFVSGAAGAVGSMVGQI
                     AKLRGAGRVIGSAGSAAKVERLTALGFDAAFDYHDGPVSKQLRAAAPDGVDVYFDNVGG
                     DHLEAAIGAMNVHGRAAICGMIAQYNATEPPPAPRNLALVIGKRLTLRGFLVSDHGHLR
                     EQFVQEVAGWLREGRLSYDETIVDGIEQAPEAFLGLLRGENLGKMLVRL"
     aSDomain        complement(17964..18890)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PVK74_RS12335_PKS_ER.1"
                     /evalue="4.90E-21"
                     /label="PVK74_RS12335_PKS_ER.1"
                     /locus_tag="PVK74_RS12335"
                     /protein_end="328"
                     /protein_start="19"
                     /score="67.1"
                     /tool="antismash"
                     /translation="FRLVTTEVPTPGPGQVVVRNRFMSVDPYMRGRMNDVKSYVPPFAL
                     DAPLDGGAIGEVVAGEAGGVKPGDTVLHGLGWREYALVDAKGARKIDPDLAPVTAHLGV
                     LGMTGLTAYAGLLDVAAMKPGETVFVSGAAGAVGSMVGQIAKLRGAGRVIGSAGSAAKV
                     ERLTALGFDAAFDYHDGPVSKQLRAAAPDGVDVYFDNVGGDHLEAAIGAMNVHGRAAIC
                     GMIAQYNATEPPPAPRNLALVIGKRLTLRGFLVSDHGHLREQFVQEVAGWLREGRLSYD
                     ETIVDGIEQAPEAFLGLLRGENLGKMLV"
     CDS_motif       complement(18474..18518)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PVK74_RS12335_0001"
                     /evalue="8.90E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="PVK74_RS12335"
                     /protein_end="158"
                     /protein_start="143"
                     /score="8.9"
                     /tool="antismash"
                     /translation="GETVFVSGAAGAVGS"
     gene            complement(18953..19378)
                     /db_xref="GeneID:91356953"
                     /locus_tag="PVK74_RS12340"
                     /old_locus_tag="PVK74_12340"
     CDS             complement(18953..19378)
                     /codon_start=1
                     /db_xref="GeneID:91356953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785232.1"
                     /locus_tag="PVK74_RS12340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12340"
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="WP_064445243.1"
                     /transl_table=11
                     /translation="MQVLYTASARATGDGRDGHVRTSDGTVELDLAVPKEMGGAGGAAN
                     PEQLFAAGYAACFHSALRVVARKAKADVSGSVVEAEVGIGPNGSGGFGLAVTLVVDLPA
                     VERAAAEQLVDAAHQVCPYSNATRGNVEVTRTVREAR"
     gene            complement(19380..19826)
                     /db_xref="GeneID:91356954"
                     /locus_tag="PVK74_RS12345"
                     /old_locus_tag="PVK74_12345"
     CDS             complement(19380..19826)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356954"
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018789360.1"
                     /locus_tag="PVK74_RS12345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12345"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_043331106.1"
                     /transl_table=11
                     /translation="MTDDLVLRRQVCFALYAASRAMTDVYRPILDEHGLTYPQYLVLLV
                     LWERDDDAPTVSELGAALRLDSGTLSPLLKRLEAAGLVVRTRSAADERRVEVGLTGQGR
                     ALRERMCDVPRQVATATGLTEAELVFLHGILTRVTETIHRQKEQ"
     gene            complement(19907..20329)
                     /db_xref="GeneID:91356955"
                     /locus_tag="PVK74_RS12350"
                     /old_locus_tag="PVK74_12350"
     CDS             complement(19907..20329)
                     /codon_start=1
                     /db_xref="GeneID:91356955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785234.1"
                     /locus_tag="PVK74_RS12350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_12350"
                     /product="RidA family protein"
                     /protein_id="WP_043329499.1"
                     /transl_table=11
                     /translation="MTAAPPEPPADAGVVTRLGSGGPWEALYGYSRVVRAGSLAITAGC
                     TSTVDGRVAHAGDAAAQTAQAIRIGLDALAEVGAGPGDVVRTRMYVTDRIFADEVGRAH
                     NAVFGPVRPVATMVVVAGLIDPDLLVEVELEAYLPA"
     misc_feature    20465..20480
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.05"
                     /tool="antismash"
     misc_feature    20844..20858
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
ORIGIN
        1 cgtcggtcac ggggtctcct ccggtgagct gaccggcagg tcggtgaaga agcaggtgcg
       61 ctgcccggtg tggcaggccg cgccgacctg ctccacgctg accagcagcg cgtcgccgtc
      121 gcagtccagg gccaccgagc gcacgtactg gtggttgccg gaggtggcgc ccttgaccca
      181 gtactcgccg cggctgcgcg accagtaggt ggcccggccg gtggtgagcg tgcggtgcag
      241 cgcctcgtcg tccatccagg cgaccatcag cacctcgccc gtgtcgtggg cgcggaccac
      301 ggcggcgacc aggccgtccg gggtgcggcg gagtttggcc gcgatggccg ggtcgagccg
      361 ggacggccgg gccgggccgg gactgggggc gccggtcagc ggcgcgtcag gggcgggcac
      421 ggttgaccat tctcccgcac gcggcccggg gaccgccgac gtgtcccggg aggcgggcgt
      481 caccgtcgcc agcgcccggc ccagctgccg caggtagcgg tccgcccggc cgtcggtgag
      541 cgcctcggcc aggtcggtcc cggtggcccg ggcgatctcc gccgcgtacg ggcgcaccag
      601 cgggaggatg ccggtgacca gccgtccggc ggcggccccg acctcggccg ggtcgccggg
      661 gcgcagcccg aggcagagga gcatgtcgtc gcggtagccg gccggggcga ccggcaggtc
      721 cagcgcggcg gtcagggcgg cccggcggga caccacgcgc accgacgggt tggccggccg
      781 cagcaccgag gggcagagcc gggccaggtc ggccgcggcg agccggaccc cggccgggtc
      841 accggccagg cgcgcggcgg cgaccttgcc cagcgtggcg atcagctcct ccaggcgcgg
      901 ctcgtccgcg ggctggcaga gcaccggcag gtcgatccgg cgccgccact ccggcaccgc
      961 ccagagcagc cgggccggcg cggtgaccgg gagcccgaac gcccagtcgg cgggctggcc
     1021 gagccggcgt acccaggaac ggacgtcgcg ggcggccacg gagacgtgca ccaggcggcc
     1081 gccgaactcg gtcaggtacg cccgccgggc cgcgtacggc gtgccgcggc gggacgtgac
     1141 cggccggggc ccgccggtgg cgcgtggctc gtcggcggcc accagcacgt ccacgtccac
     1201 gtcgctgtgc tcggtggcgg cccgccgggc gtggctgccc cgcagcatga tcccgacgac
     1261 cggccggtcg gcggcgtgcc gcaggcgggc ggcccagagg tcgaggaacc cggtgtcgga
     1321 caacggagct ggacccactg cctcatggtg cccgaaacct gatcttccga tgccggactc
     1381 cctgtccgcc gccgggtgtt cagcccgact cctcctccgc ccgccggtac gcgtcgatct
     1441 tgtattcgag aaccttcagg tcctcctcca gctcggccat ccgggccagc acccgggcgc
     1501 ggtgcgcctc gaacagcgcc cgccgcgcgc cgagggtgct gtcgccgtgc cgggccagct
     1561 cggcgtagcg gcgcatgtcg cgcaccggca tcccggtgcg ccgcagccgg gtgagcagga
     1621 acagccagtt gacgtcggac tcggtgtagc gccggcggcc ggaggagtcc cgtccgacgc
     1681 ggcccaccag cccctcctgc tcgtaccagc gcagcgtgta ggtggtcagg ccgacccgtt
     1741 ccgccgcctc acccacggtg aggctcatct cccgcgtgct gatgtccacg ccctccaggc
     1801 ttccagttcg agcccactcg aagtcaagtc cctcgttgcc tcgccgacgg aattcatcta
     1861 gcgttgagtt caccgggtga tgaattgacg gaggcgagca tggacgacgc ggtgtcggtc
     1921 cgcgagctgg tggtcgaccg gggcgggcgg cgggtgctgc acggcatcac ctgcggggtg
     1981 ccccggggca cggtgaccgg gctgctcggg cccagcggca gcggcaagac cacgctgatg
     2041 cgcgcggtgg tcggcgtgca gacggtcggc tccggcgcgg tcgacgtgct cggccgcccg
     2101 gccggctcgg ccgacctgcg ccgccgggtg ggctacctga cccaggcgcc gagcgtctac
     2161 gccgacctga cggtgcggga gaacgcccgc tacttcgcgg tgctccaggg ccggggccgc
     2221 gccgaggccg accgcgcggt caccgacgtc ggcctgggaa aggcggccga ccagctcgtc
     2281 ggcacgctct ccggcggcca gcgcagccgc gcctcgctcg cgtgcgcgct ggtcggcgag
     2341 ccggagctgg tcgtcctcga cgagccgacg gtcggccagg acccggtgct gcgggccgac
     2401 ctgtgggccc ggttccacgc catggccgcc gccggcacca cgctgctggt gtccagccac
     2461 gtgatggacg aggccgcccg ctgcgaccgg ctgctgctga tccgcgaggg ccggctggtc
     2521 gccgacgaca ccccggccgc ggtccgcgcc gccaccggga ccgacgacct ggaagaggcg
     2581 ttcctgcgcc tgatccgcga cgccgaggga gaggcgcgat gaacggacgg atcctggccg
     2641 ccaccaccgg gcgcatcctg cgccagctcc ggcacgaccg gcggaccgtg gcgctgctcg
     2701 tggtggtgcc gtcggtgctg ctcacgctcg tctacttcat gtacgtcgac cagcccgccc
     2761 cgcccggcgc gcccagcacg ttcgaccggg tggccctgat catgctgggc ttcttcccgt
     2821 tcatcatcat gttcctcgtg accagcatcg ccatgctccg cgagcgcacc acgggcacgc
     2881 tggagcgcct gctcaccacg ccgctgggca agctcgacct gctgttcggg tacggcatcg
     2941 cgttcggcct ggccggggtg ctccagtcca ctgtcgcctc ggtcgtcgcg taccgggtgt
     3001 tcggcctgga gaccgcgggc agcgcgtggc tggtcgtgct gatcgccggg gtgaacgcgg
     3061 tgctggcggt ggcgctcggg ctgttctgct cggcgttcgc ccgcaccgag ttccaggcgg
     3121 tccagttcat gccggtggtg gtggccccgc aactgctgct gtgcggcctg ttcgtgccgc
     3181 gcgaccagat ggccggctgg ctccaggcgg tcagcgacgc gctgccgctg tcgtacgcgg
     3241 tcgaggcgct gcaggaggtc ggcgcgcacg ccgagccgac cgggacgatg tggcgggacg
     3301 tggcgatcgt gaccggggcg gcggtggcgg cgctggtgct ggccgccgcg acgctgcgcc
     3361 ggcgcagcgg gtgaacgcgc ggcgcaccgg gcggcggccc ggcactccgg acacccgcga
     3421 ggcgatcctc gccgcggcgc gggaggcgtt cgccgagcgg gggttcgacg ccgcgtccat
     3481 ccgggccatc gccgccgcgg cgggagtgga cccggcgctc gtgcaccact acttcggcgg
     3541 caaggaggag ctgttccggg ccgcgacggc gttcccagcc gacccgggac ggctgctgcc
     3601 ggcggtgctc gccggcggcc cggacgcgct cggcgagcgg atggtccggg tgttcctgga
     3661 ggtctgggac tcccccaccg gcaccgccgc ggtggcgctg ctgcgctcgg cggtcagcaa
     3721 cgactggacc gcgcgcctgc tgcgcgagtt cctggtcacg caggtgctgc ggcgggtgct
     3781 cgaccagctc gacgtcgacc cggcgcagcg cgcgctgcgc ggcggcctgg tcgccaccca
     3841 gctcgccggg ctggcgatga tgcggtacgt gctccgcctc gacgcggtcg ccaccgccga
     3901 gccggcgacg ctggtggccg ccgtcggccc gacggtccag cggtacctca ccggcgacat
     3961 cacctgagcc gtcgcggctc aggccgcggc cgcccggggg cagagcatcg ggtgcagcag
     4021 gcgggacaac tccgccacgt cggcgaccgg ccgggggaag gcgagccggg cccgccgggt
     4081 cgcgccgggc cgcccgtgcg cgaccagcag gccgtacctg tcgatccgga ccacccgcgg
     4141 gatctggtcg ccgggcaggt ccagccgccg ccgaaggtag tcgccgacct gctcggcgtg
     4201 gtggtcggcc aggtccgcga gcagggcggc ctcgaccggg tgcagcgggt ccggctcggc
     4261 ctccgcgaac gcctccgggt cgatccggcg cacccgcccg gcgcgttccc agcgggcctc
     4321 ggccacctcg aagcggtgca ggtggaaccg gctgcccacg tcgagcagat cggcgaccgg
     4381 gtcggtggcg gcgaagtcga cagccgcgtc gcgcgcctcg tccccgttca gccgcgtcgc
     4441 ccagccggac acccaggccc ggccgagcga gggcgccccg gccgccggcg gcaggtcgag
     4501 cacgtcgagc acggcggcca cgtcggcgtc gcccgccggc ggcacgagcg ccgcggcgag
     4561 gtcactgacc acgggtacga gcagcagcac ccgcccgtcc gggtcgacgg cgtgccggac
     4621 ctggtgcggg ccggggtgcc gggccaggtg gacgagggcg ggcaaccggc ccgcgacaag
     4681 ggttcgcacg atctccgccg ggctgggccg catgatcccg acctcctcaa gataggttag
     4741 gcttacctaa gaagcaggct agacgatcgg agacgccccc gtgaaccacc cccggcccaa
     4801 agcccggctc tcccgggccc tcggcatccc gctgacccgc aagtgcgtgc ggtacttcga
     4861 gcggcgcccc tatcccccgg gcgtgcacgg ccggtcccgc cgcaccacct ccgactacca
     4921 ggtgcggctg ctggagaagc agcggctgcg ccaccagtac aacgtcagcg aggcccagtt
     4981 gcgccggctg ttcgacgagg ccgcccgggc cgccggcaag accggcgaca cgctcgtcgc
     5041 gctgctggaa cgacgcctcg acgcggtggt cctgcgggcc gggctggccc gcagcatcta
     5101 ccaggcccgc cagctcgtcg ggcacggcca catcacagtg gacgggcgca aggtcgaccg
     5161 gccgtcgtac cggctgcggc ccggccaggt ggtcggcgta cgcgagcgca gccgcacgct
     5221 gccaccgttc cagctcgccg ccgccggggc gcacgccgac gcgcagcccc ggccgtacct
     5281 gtcggcgcag ccggcgcagc tgcgcgccac gctggtacgc gaaccggccc ggcacgaggt
     5341 gccggtggtc tgcgacgagc aactggtggt ggagttctac tcccgctgac cggttaccgg
     5401 gtctgctcca accaggacgc gtacagcagc gcgtacacgg agtcggtgtc gcggaccagc
     5461 tcgtcgtgcg ggccacgctg cacgatccgg ccccggtcca ccacgatcac ctcgtccgcc
     5521 gcctgcgcgg tggacagccg gtgcgcgatg gcgagcgtgg tccgcccccg ggtcaccgcg
     5581 tcgagcgtgc gttgcaggcg tacctcggtg gccgggtcga cggcgctcgt cgcctcgtcc
     5641 agcaccagca ggtccgggtc cgcgacgtac gcccgggcca gcgccacgag ctgccgctcg
     5701 ccgacgctga gcgcctcccc gcgctcaccg accggcgtgt ccagcccgga cggcagcccg
     5761 tccagccagt cggccaggcc cagctcgccg aaggcggcgg tgagccgctc gtcggtcagg
     5821 tcggggcggg cgaagcggac gttctccccg accgtggcgt cgaacaggaa gccgtcctgc
     5881 ggcaccatca ccacccggga acgcagcgag tcgaaacgca cctgccgcag gtcgacgccg
     5941 gagagcagca ccgcgccctc ggtcgggtcc atcagccggg tgagcagctt ggcgaacgtg
     6001 gtcttgccgc tgccggtctc gcccaccacc gccacccggc tcttggccgg gatgtccagc
     6061 gtcacgtcgt gcagcaccgg cgggccgccc ggataggcga acgtcacgcc ggcgaaccgg
     6121 gcgtccagcg gcccgggcgg cagctcccgc ccctgctcgc ccgggtcggc cacgtccggg
     6181 gagacgtcca gcacgtccag cacccggcgc cagccggcga tcgcgttctg cgcctcgttg
     6241 agcacctcgg tggcgatctg caccggctgg atgaagagcg tgaccaggaa caggaacgcg
     6301 gtgagctggc cgaccgacag cgtgcggtcg acgcccaggc tcaccccgac cacgaccacg
     6361 ccggccagcg ccagcccggc cgccagctcc cccaccgagc tgcccatgat gctgatccgg
     6421 atcgcccgct gctgggccac ccgctgaccg tcgatggccg tgtcgagccg ccgcgcggtc
     6481 cgcccggcga tgccgtacgc ccggatcacc ggcgcgccca ccacgctctc gccgatcgcg
     6541 ccgagcagcg tgccggtgcg ctgccgcacc aggccgtagg ccccggcgag gcggcgctgc
     6601 aactgccgga tcaccagcac cgccggcgcg aacgcgacga gcaccacgag cgtcaactgc
     6661 caggagtacg cgagcatcac cgctgtggtc accagcagct ggcccaggtt gacgatcagg
     6721 atcacgccgc cccactgcag gaactgggtg atctggtcga cgtcgctggt cacccgggag
     6781 accagcgagc cgcgccgctc ggactgctgg tgcagcatgg acaggtcgtg cacgtgccgg
     6841 aacgcccggg tgcgcacccc ggccagggcc gtctcgctca ccgtgaacag ccggcgcatc
     6901 atcaggtagc cgcaggcggt ggtgaccacc agcaccccgg cggtgatcgc cacggtgagc
     6961 gagatgacgt tcaggtcgag cccgccgacg atgccgtggt cgatgccgcg ctgcaccgcc
     7021 accggcacgg cgacccggcc gaccatgtag accagcgcca gcgcgagcgt gccggcgaga
     7081 ccggtgcgca gctccgggga gagcgccagc ccgcgccgca acgtctgcca ggtcgactcg
     7141 gtggtctcgg tgctccggtc cgcctccgcc gtcgtcgcgc tcaccgctcc acctccaggc
     7201 cggaggccag cggcgtgacc tcgtcgtacg tctgcttctg ctcgcgttcc tgctcggcct
     7261 gctcgtacgc ggtgaccagg tcggcgtagc cgggcacggt ggccagcagc tcggtgtggg
     7321 cgccgcgggc gaccacccgg ccctgctcca cgtagatcac ctcgtcggcg agcgcgatgg
     7381 tggcccggcg gtacgccacc accaggatcg acgccggggc gccgccgtcg gcgggcgcgc
     7441 gcagcccggc caggatggcc gcctcgacgc gcgggtcgac agcgctcgtg gcgtcgtcga
     7501 gcaccagcag ccgggggcgt ccggccagcg cccgggccag cgtcagccgc tgccgctgcc
     7561 cgccggacag cgaggtgcct cgctcgccga ccatggtgtc cagcccgtcc ggcagcgcgg
     7621 ccacgaagcc gtccgcctcg gccagccgca gcgccgccca cacctcgtcg tcgccgatgc
     7681 cggcccggtc cagcgcgatg ttggcccgga ccgtgtcgtc gaagacgaac ggcacctgcg
     7741 ccaccagcgc cacgttgccg gcgagcgagg cggcggtcag ttcccgcacg tccacgccgt
     7801 ccagcgtgac ccgcccggcg cccgggtcga ccaggcgcac ggccaacgac gcgatcgtgg
     7861 acttgcccga accggtgggc ccgaccaggg cgacggtctt cccggctggc acggtgaacg
     7921 tcacctcgcc gagcacctgg gcgccgggca ggtgcgcctc ggccggctcg tacgcgaagt
     7981 gcacgtcgtg gaacgcgagc gtggccggcg tacgggtggc cgggtcgagc gtcctcgtgc
     8041 cgtacggcat ctcgcctgtc gcgtcgagca cccggcgcac ccggtcccac ccggcgacgc
     8101 tgcgcggcag ctcggccagc acccagccga tggcgcgcac cgggaaggcc agcacggtga
     8161 acaggaacgc gacgctgacc agctcggaca cggtgatcgc gccctgccgc agccggatcg
     8221 cgccgaccac cagcacggcg agcgtgccga ggctgggcag cgtctccagc atcgggtcga
     8281 agacgccgcg cagccggccg accgagatca gcgcgtcccg cagctcgccg gcgcgggcgg
     8341 cgaaacgggc ggtctcctgg gcctcgcggc ccatcgtctt gaccaccaac gcgccgtcga
     8401 agctctcgtg cgcgatgccg ctgacctcgg cgcgcagccg ctgcgcccgg gcctgccggg
     8461 gcgccatccg gcgggagtag accacgttga gcgcgaacag cgcggggaac acggcgaggc
     8521 cgaccagggc cagcgcccag tcggtgacga acagtgacgc caccgcgccg accagcatca
     8581 ccagcgtgcc gaccgcgaac ggcagcggcg cgatcgggta ccaggccgcc tccacgtcgg
     8641 agttggcgtt cgacagcagc gtgccggtgg agttgcggtg gtgccaggcc agcggcagtt
     8701 ccaggtagcg gcgggtgacc cggcggcggt aggcggcctg gagccggtac tgcatgtaac
     8761 cggcgccgag ccgccggccg aagatgccga cgacccgcag cacgctgatg ccgagcagcg
     8821 ccgccgcggc cagcgccagg gtcccgcggg ccacctcgcc gcgctcgacc gcgggcacga
     8881 cgaccttgcc gaccaccccg ccgaccacgt acgcgctggc gatcaccagg aggccgaaca
     8941 gcacgctgcc gctgaccgcc accgcgaaga tccgcggctg ttcccggatg gcccggccga
     9001 gcacccgtag ccctctgccg agcacgtccc gacttgtccc gctcgccacg ttcgcccccg
     9061 ccgtaagccg caattttctc ccccatcctt accgctcgcc gccagctccg ccgacccggc
     9121 cgggatatgt ccgccgtcac gttcgcaccg gacctgggcg gacaccggcc ctcgatgctc
     9181 gcggcccgcc gtagcgccgg gcgtggcgcg ccgatcggcc gcgacgggcc tacgatcggg
     9241 ccatgccgcg gtacgcccga acggagcgcg aggcgctcgc cgacctgatg ctggagctgg
     9301 gaccggacgc gccgactgtg aacgaggggt ggaccacccg cgacctggcg gcgcacctgc
     9361 tggtgcggga gcgccggccg gacgcggcgg gcgggatcct gctgccgccg ctgcgcggct
     9421 acggcgagtc ggtccgcagg cggatcgccg ccgggccgta cgccgacctg atcgcccggg
     9481 tccgccgtcc cccggtgtgg agcccggtga gcaacccgct caccgacgag atcgcgaacg
     9541 ggatggagtt cttcatccac cacgaggacg tccgccgggc ccggccgggc tggcagccgc
     9601 gtgacctgcc ggccgggcag caggcggtgc tctggaagcg ggtcgccctg ctggcccgga
     9661 tggcgctgcg gcgcttcccg gccgaggtgc tggtgcaggc gccggggcac ggcgagctgc
     9721 gggccggtgg cggcggcgag cggctgcggc tggtcggcgc gccgggggaa ctcgtgctgt
     9781 tcctcaccgg gcggcagcgg gtggcccggg tccaggtgga cggtccggcc gagcgcgccg
     9841 agcgtctgcg taccgccgaa ctgggcctgt gacagacgtt tccgcccgtc cacccaggcg
     9901 atcgtagaat gtggacaccc ggcgttcgat aacgttcgcc ggctgccgta cgctcctgcg
     9961 caccggcccg accctgcggg gcggcggaca ggggacgacg atgcgggact tcgcgctctc
    10021 ggcgctgcac gagccgccct ttccctcccg gtgtcacccg gccgcggacg aggtggccgc
    10081 gcagagcgtc gcctgggtgc gcggtttcgg cctggtcaag acccaggccg gcctgctgcg
    10141 gctggccggc gcccatgcct cggagctggc cggacgggcc tgccccgagg cgtccccggc
    10201 cggtctgcgg ctgctcaccg acctgatcaa ctggctgttc gtggtggacg acgcctgcga
    10261 cgacgacggg ctgggcgccg cgccgacagt gctcgcgccc accctggcgg cgctgctgga
    10321 agtgctcgac cggcacggtg acccggacgc gcccgcgccc accgacgccg gcccgatggg
    10381 cctggcgctg cacgatctgt gccggcgggc gcgcggccgg ggccggccgg cgcacctgat
    10441 gcggctggtg agccagttgc gggagtacct gctggcgctg ctgtgggagg cggcgaaccg
    10501 ggagcgccgg cgcgtgccgg gggtcgccga gtacgtgcag atgcgccgcc acaccggcgg
    10561 cgtacgcccc agcttcacgg tgaccgacct ggcccgcccg tccctgcccc gggccgacca
    10621 gcgggcgacc ccggcgctca ccgcgctgga cgccctcgcc accgacctgg tctgctggtg
    10681 caacgacgtg ttctcctacg gcaaggagcg gggcgtcacc ccggacgcgc acaacctggt
    10741 gaccacgatc gcgggcgaga ccgggcagga cgagtcggcg gcgctgaacg cggcggcgaa
    10801 ccgcttcaac gcggccctcg cctcgtacgc ggagcgggac gcggcgttga gcgccggggc
    10861 cgacgagggg atgcgggcgt tcctggacac ccgccgggac tggatccggg ccacctacga
    10921 ctggtcccgc gccgccagcc gatacgcctg atccgattcc agaagtcggg accggtggcg
    10981 actcggccga tcagggctag ccgctggccg ggtacaggca atacccttcg gtaaccgcag
    11041 accggcgtga cccccgtcac gtccctccac ccctgaaggc ggctacagcg atggctctcg
    11101 atgtaccgta ccgttccgta cccgacatgt tcctcaagcg cgtggcggac tcccccgacc
    11161 gccaggcgtt cgctcacccc gcacccgacg actcgggccc ggtctggctg acgtgggagc
    11221 aggtcgggca gcgcgcgaag gcgatcgccg ccgggttgca cgggctcggt gtcggcctgg
    11281 agaacccggt ggcgatcctg gccaacaccc ggctggagtg ggtgcttgcc gacttcggca
    11341 tcatgtgcgc cggtggggcc accaccaccg tctacccgac caccgagccc gacgacgcgg
    11401 tctacatcat cgccgactcc ggctcgaagg tgctgttcgc ggagaacccg gcccaggcgg
    11461 cgaagatcgc cggagcggac ctgcccgcgc tgacccacgt ggtgctcttc gacggcgcgc
    11521 cggacccggc cgccgccgtc ccgcagctca ccctggccga gctggaggag cgcggcgccg
    11581 ccgcgctgag cgccgagccc gacctgatcg acatgctcgt ggccggcatc ggcccggacc
    11641 acctggcgac gctcatctac acctcgggca ccaccggccg cccgaagggc gtggagctgc
    11701 tgcacggcgg ctggtgctgg gagggcgtgg cgcaggccga gctgggcctg ctgcgcaccg
    11761 acgacctgca gtacctgtgg ctgccgctgt cgcactcgtt cggcaagacg ctgctctgcg
    11821 gcgccaccca cgtcggcctg cccacgtacg tcgacggccg ggtggacaag ctggtcgacc
    11881 tgctcggcgt gatccggccg acgctgatgt gcggcgcgcc ccgggtcttc gagaaggtct
    11941 acaacaaggc ggtcaccacc gcgcagggcg cgggcggcgc gaaggccaag atcttcgcct
    12001 ggggcgtcga ggtcggcaag gagaaggtcg cgctggagca ggccggcaag ccggtgccgg
    12061 ccgggctgcg gatgaagtac gcgctggccg agaagctggt gttcagcaag ctgcaggccc
    12121 ggctcggcgg ccggatgcgg gtgctggtct ccggcgcggc gccgctgagc aaggagatcg
    12181 ccaccttctt cgccgccgcc aacctgccca tctccgaggg ctacggcctg accgagacca
    12241 gcgccggcgc gttcgtgaac ccgcccgacg ggctgaagat cggcagcgtg ggccgggcca
    12301 tgggtgatct ggagtgccgg atcgacaccg acggcgagat cctgatgcgg ggcaagccgg
    12361 tcatgcgggg ttaccacaac ctccccgagg agaccgccgc cgcgttcacc gaggacggct
    12421 tcttccgcag cggcgacatc ggcacgctcg acgacgacgg ctacctgcgc atcaccgacc
    12481 gcaagaagga cctggtcaag acgtccggcg gcaagtacgt cgcgccgtcg cacatcgagg
    12541 gcatgttcaa ggcggtctgc ccgtacacct cgcaggcggt ggtgatcggg caggcgcgca
    12601 actactgcac catgctcgtc acgctggacc cggacgcgat caagggctgg gccgccggca
    12661 ccccgctgga gggcagcgac tacaccacga tcgtcacctc gccgcaggcg cgggagatgg
    12721 tcgaggggta cgtcgccgag ctgaacgcca agctcaaccg ctgggagacg atcaagaagg
    12781 tgacgatcct cccccgtgac ctcaccatcg aggacggcga ggtcacgccg tcgctgaaga
    12841 tcaagcgccg gagcgtggag acgaacttct cctccgagat cgacaagatg tacgagggca
    12901 cgctcgccga gctgtgaccc gcaccgccag ccggtagcgc cggccgtgcc ccaccgtccc
    12961 ggggcacggc cgttcgcgtc ggcgccggtc agaggtgctg ctgccgccag cggctctgct
    13021 cggcctcggc ggcgatctgc tcctccagcg cgagctggcg tacccggcgc cggtgaccgt
    13081 tctcgccccg ggtctcccaa gccactcccg cgccggtgac caccgccagc acgatcagcg
    13141 cgaccagctc cggcacacgg aacacgaatg gggcgaccgc ggtcagcgcc cccacggtgg
    13201 tcagcagccg ccagtggatc tcgcgcagcg ccacccacca gcacccggcg acgccgagca
    13261 ggtgcaacgc gaccccgccg aacaggatcg cgccccagaa gtcgccgagc ggcagccccc
    13321 aggcgggcgt gtgcggatcg gcggcctcgg ccagcaggtc cttgaggccg agcgcgtaga
    13381 ggatgatccc ggcgactatc ggcaggtgca ggaacgtgta cgcggtgcgg gccagccgca
    13441 gccgtgtggc gcggtcccgg gcctggtgca ggacctgttc catggcgaac gccagcgtgt
    13501 cgaagtacgc ccaccacagc gccgccacga ccgtgatgcc gagcaacgcg gcgatcgcca
    13561 ccgggccggt gagcggcagc ccgcgcttcg ggccgagccc cagcgcgatg atcgactcgc
    13621 cgagtgcgac gagcacgatg agcgcgtgcc gttccgccca gtgcccggcc gagagcacca
    13681 cccaccactg ctggcccagg accgtcccgg cgacgtactc gacaagcagc gccagcgtcc
    13741 agagcgccag ttgcagcccg accgcgaacc gctcctgcgg cagccggccg gggagtgtgc
    13801 cggcgacgac aagcagcgcc gtggccaccg tcggggccag gaagcgcatc cgcagtcccc
    13861 ggcgccgggc cgggtcggcg cggtcggccc aggcgaagac ggtgagctgg gcggtccgga
    13921 tcacgaagta gcacgcggcg aagaccagcg gcccgggcag ccagccaccg ctgttggcga
    13981 acgcgctggg cgtgctgagc acgagcagga acgtggccgc cacggtgacg acgccgatca
    14041 gcggcagcat cccctggtcg gcgcggaacg cgttgcccat ccgggcgaag ccggtccacg
    14101 accaccagag cagcgccagc accagcagga accggtagag gttggcgggc gtgagcaccg
    14161 aggcggtgag cgtggtgacg ctcaggaacg cgaagacgaa gaccaggtcg tagaagagct
    14221 ccagccgagt ggtgcgggag cccggcgcgc tgcgccgcac cgcccacgac caccggaccg
    14281 cgtccccgtc tcccacccgg gcagtgtgcg ggcgcggacc cgcccgcagc tgtggttcgg
    14341 gcggttcacc accggatcgg gcgggcggtc aggcgatgac gctcggctcg cgccactgcg
    14401 ggcggctggt gcggtccagg tcgtagcgca ccgcggcgag ccggcccacc gcttccacca
    14461 gttcctcggc gggcagcgtg aagggcaacc gcaggaagcg ctcgagcgtc ccgtccaggc
    14521 cgaaccgggg tccgggcgcc agccgtacgc cgacctcctc ggcggcccgg gccagcgcgc
    14581 tggagatcgg gccgtccagc tcggcccaga gcgtcacgcc gccgcgcggc ggcgtgaccc
    14641 gccagtcggg cagctgctcc gcgagcgccg cgaccagggc gtcgcgctgc gcggcgagct
    14701 gggcccggcg ggcggccacg atggccggcg cctcggcgag caggtgcacg gcgacgagct
    14761 ggtcgagcac cgggctggcc atgtccaccc cgacccgggc cgcggcgagc cgctgcacct
    14821 ggggcgcgga ggcgcggacc cagccgatcc gcaggccgcc ccagtagggc ttgctcatcc
    14881 cgccgatgct gatcacccgg gagtgcctgt cgaagaccgc gaccggcggc ggcagcgggg
    14941 tgccgtccag cggcaggtcg acgaaggact cgtcgacgac gaggtcggtg ccggccgcgt
    15001 gggccgcgcc gaccagccgt tcgcgcaggt cggccgccat caggtggccg gtcgggttgt
    15061 ggaactccgg gatcacgtac gcgagcttcg gccgggtctg ccggatgctg ccgagcagca
    15121 gctcggcgtc ccagccctcg tcggacaggc cgtgcgtggc gatccgggcg cgccgggcgg
    15181 ccagcgcggc cagcgcgttg gggtaggtgg gtgactcgac gagcaccgcg ccgccgggcg
    15241 acagggccag ccgcagcacc aggtccagcg cgtgctgggt gccgctggtg accatgatct
    15301 gctccgggct ggtgggcagc ccgcgctcgg tgtacccgcg ggccaccgcc tcccgcagct
    15361 cgatgatgcc ggtcgggtgg tagccggccc cgccgaggta gcggggcagg tcctcggcgg
    15421 ccgcccgggc ggccgggacg agctgcggcg gcgcggacag cgcggccacg ccgaggtcga
    15481 tcatgtcgcg gtcgtccagc ggcgtccaca gcccggtgct ggcgacccgg tggccgccgg
    15541 gcagcatggt ccagctcccg gcgccccggc ggctggccag gtggccgctc tcccgcagtt
    15601 cccggtacgc ggcggtgaca gtggtccggc tgatccgcag cgcctcggcc agttcccgct
    15661 cggccggcag gcgtaccccc aggggcagcc ggccgtcggc gagcaggccc cggacggcgc
    15721 cggcgagcgc ggcgtagtcg gggctgcggc ggcggcccgg cagcgcatgc cactggccga
    15781 ggagtcgcgc caattggacg ccgcgcacct ggctggtcat ggccacacct ccggaattgg
    15841 accccttacg tcctgcaatt ggcccctagg gtggcatgca tggcaccgct tggcaatctc
    15901 gggcaccgtt cggcgcgacg actcacccag ctctacgccg ggctcgtcct gtacggcctc
    15961 agcatggcgc tgatgatccg gtcggagctg gggctggacc cgtgggacgt gttccaccag
    16021 gggctcgccc ggcagaccgg tctctccttc ggcaccgtca ccatcgccgt cggcgctctc
    16081 gtgctgctgc tctggatccc gctgcggcag cggcccggcc tcggcacggt cagcaacgtc
    16141 gtggtcatcg gcctggtcgt cgacgccacc ctggccgtgc tgccgcccgg tgagggcatg
    16201 ccggcgcgtg ccgcgatgct cgtggccggg atcgtcgcca acggcgccgc caccgggctc
    16261 tacctcggcg ccgggctcgg ccccgggccc cgcgacggtc tgatgaccgg attcgtcgcc
    16321 cgtcatcccc gcttctcggt acggctggtc cgcacgagca tcgaggtcac cgtgctggcc
    16381 ctcggctggc tgctcggcgg aaccgtcggc ctcggcaccg tggcgtacgc gctgaccatc
    16441 ggcccgctcg cccagttctt catcccggtc ttcgcgctgc ccgcacggcc ggcgagcggc
    16501 gcttacgcta cgtgaccggc gccgggccga ccgccacggc ccgaagcgat ccgcaacgcg
    16561 ctgagctgcg gtgacgaaga acagcaaaac caggtgtttc ctccgccgtc gcggccgggc
    16621 atcattcctg catgggggag aacggatggc gttggagcga cgcctggatc ttcgtcgcgc
    16681 ttgtcatcgc cagtggcgcc ggccggcacc ggcggtccgc gtcgacacgc cgccccgaag
    16741 gcgtacgact ggccgacgtc ctctccaccg ccgaccacct aaaccaggcc atccccgagc
    16801 ggcacgaggt ggagggcgcg gtccggcggc tcgtcggcgc gggcctggtc agcgtcgccg
    16861 acggctggtt ccgggtcaca ccggacggtg agcggctctg gcgcacccgc cccagcgccg
    16921 ggctcggcac cactgtggac acggtgcagg gcgtgctgac ccgccggcac ccgcccggtg
    16981 agtccgagtg gcagctcgac gaggacgacc acgccgccgc cgtgcaggag tacgtggtcc
    17041 gctcgatccc gatgccgcgc cgctcccccg aggggcactc cggccggcag tgagcgcgcc
    17101 tcagcgcacc gggtgcccgg cgccgcgcag cgcgtccttg acctcgccga cggtcagctc
    17161 accgaagtgg aagacgctcg ccgcgagcac cgcgtccgcc cccgcgccga cggccggcgg
    17221 gaagtgcgcc acctcgcccg cgccgccgct ggcgatcacc ggcacgtcga ccacctcccg
    17281 gaccgcctgg atcagcggca ggtcgaaccc ggccttggtg ccgtcggcgt ccatcgagtt
    17341 gagcaggatc tcccccgcgc ccagctcggc gccgcgcgcc gcccactcga ccgcgtccag
    17401 cccggtgccc cgccgcccgc cgtgcgtggt cacctcgaaa ccgctcggcg tcgtgccgtc
    17461 gggcgcgcgg cgcacgtcca gcgagagcac cagcacctga ctgccgaacc ggtcggcgat
    17521 ctcggcgatc agctccgggc gggcgatggc ggcggtgttc acgcccacct tgtccgcccc
    17581 ggcccgcagc agcgtgtcga cgtcggcgac ctggcggacg ccgccgccca cggtgagcgg
    17641 gatgaagacc gactcggcgg tacgccgcac cacgtcgagc atggtgccgc ggtcactgga
    17701 cgaggcggtg acgtcgagga aggtcagctc gtccgcgccg gcccggtcgt acgccgccgc
    17761 cagctccacc gggtcgcccg cgtcgcgcag gtcgaggaag ttgaccccct tgaccacgcg
    17821 cccggcgtcc acgtccagac acgggatgac ccgtaccgcc accgtcatgc cccgagccta
    17881 gccaacgcgc gggcggtggt gacccgccgg tgaggccggt caccaccgcc cgtggtggta
    17941 cgggttcacg ccggtcagag acggaccagc atcttgccga ggttctcgcc gcgcagcagg
    18001 ccgaggaacg cctccggggc ctgctcgatg ccgtcgacga tcgtctcgtc gtacgacagc
    18061 cggccctcgc gcagccagcc cgccacctcc tgcacgaact gctcccgcag gtgaccgtgg
    18121 tcactgacaa ggaagccgcg cagcgtcagg cgtttgccga tcaccagcgc caggttgcgc
    18181 ggcgcgggcg gcggctcggt ggcgttgtac tgggcgatca tgccgcagat ggcggcccgg
    18241 ccgtgcacgt tcatcgcccc gatcgcggcc tccaggtggt cgccgccgac gttgtcgaag
    18301 tacacgtcga cgccgtccgg cgcggccgcc ctgagctgct tggacaccgg gccgtcgtgg
    18361 tagtcgaacg cggcgtcgaa gccgagcgcg gtgagccgtt ccaccttcgc cgcggagccg
    18421 gcgctgccga tcacccggcc ggcgccgcgc agcttcgcga tctggccgac catgctgccc
    18481 accgcgccgg ccgcgccgga gacgaagacg gtctcccccg gcttcatggc ggccacgtcg
    18541 agcagcccgg cgtacgcggt cagcccggtc atgccgagca cgcccagatg ggcggtcacc
    18601 ggcgccaggt ccgggtcgat cttgcgcgcg cccttggcgt ccaccagcgc gtactcgcgc
    18661 cagcccagcc cgtgcagcac cgtgtcgccg ggcttgacgc cgccggcctc gccggccacc
    18721 acctcaccga tcgcgccccc gtcgagcggg gcgtcgagcg cgaacggcgg cacgtacgac
    18781 ttgacgtcgt tcatccgccc gcgcatgtac gggtcgacgg acatgaaccg gttgcggacc
    18841 accacctgtc ccgggcccgg cgtcggcacc tcggtggtga ccagccggaa gttctccgcg
    18901 gtcggccagc cctgcggccg ggacgccaga tggatctccc ggttcatccc gctcatcggg
    18961 cctcgcggac cgtgcgggtg acctcgacgt tgccccgggt cgcgttggag taggggcaga
    19021 cctggtgggc cgcgtcgacc agctgctcgg cggccgcgcg ctcgaccgcg ggcaggtcca
    19081 ccacgagcgt cacggcgagg ccgaagccgc cgctgccgtt cgggccgatg cccacctcgg
    19141 cctcgaccac cgagccggag acgtccgcct tggccttgcg ggcgaccacg cgcagcgcgg
    19201 agtggaagca ggccgcgtag ccggccgcga agagctgctc cgggttggcc gcgccgccgg
    19261 cgccacccat ctccttcggt acggcgaggt ccagctcgac cgtgccgtcg gaggtgcgga
    19321 cgtgaccgtc gcggccgtcg ccggtggcgc gggcggaggc ggtgtagagc acctgcatgt
    19381 cactgctcct tctgtcggtg gatcgtctcg gtgacccggg tgaggatgcc gtggaggaag
    19441 accagttcgg cctcggtgag cccggtggcg gtggccacct gccgcggcac gtcacacatc
    19501 cgctcccgca gggcccggcc ctggccggtg aggcccacct cgacccggcg ctcgtcggca
    19561 gccgagcggg tacgcaccac caggccggcc gcctccagcc gcttgagcag cggggagagc
    19621 gtgccggagt cgagccggag cgcggcgccg agctcggaga ccgtgggggc gtcgtcgtca
    19681 cgctcccaga gcaccagcag caccaggtac tgcgggtagg tcaggccgtg ctcgtcgagg
    19741 atgggccggt agacgtcggt catggcgcgc gacgccgcgt agagggcgaa gcacacctgc
    19801 cggcgcagca ccagatcatc ggtcaccgcg aaaccgtaac gcacaattag gttgtgcaca
    19861 accgatcggc gtgtggtccg gggcgcgcga ggcaccccgg aacgcctcag gcggggaggt
    19921 acgcctccag ctcgacctcg accagcaggt ccgggtcgat cagcccggcc accaccacca
    19981 tcgtcgccac cgggcgtacc gggccgaaca ccgcgttgtg cgcccggccc acctcgtcgg
    20041 cgaagatccg atccgtcacg tacatccggg tccgcaccac gtcgcccgga ccggcgccca
    20101 cctcggccag cgcgtccagg ccgatccgga tcgcctgcgc ggtctgcgcc gccgcgtcgc
    20161 cggcgtgcgc cacccggccg tccacagtgg aggtgcagcc ggccgtgatc gccagcgaac
    20221 cggcccggac cacccgcgag tagccgtaca gcgcctccca cgggccgccc gagccgagcc
    20281 gggtcaccac accggcgtcc gccggcggct cgggcggcgc ggcggtcacg cgccggcccg
    20341 cagcgtcgcc agcgcctcgg cgacggtgaa cgcgcccgcg tagagcgcct tcccggcgat
    20401 cacgccctcc acgcccaccg gctccagcgt ggccagcgcc cgcaggtcgt cgagcgtgga
    20461 cacgccgccg gaggcgatca ccggggcgtc ggtgcgggca cacacctcgc gcagcaggtc
    20521 caggttcggc ccgcgcatgg tgccgtcctt ggtgatgtcg gtgaccacgt accgcgccgc
    20581 gcccgccgcg tccagccggg ccagcacctc gtacaggtca ccgccgtcgc gggtccagcc
    20641 gcgcgccgac agggtacggc cgcgcacgtc cagcccgatc gccacccggt cgccgtactc
    20701 gccgcagatc cggtcgcacc actgcggatc ctccagcgcg gcggtgccga tgttcacccg
    20761 tgccgccccg gtggccagcg ccgcccgcag cgactcgtcg tcgcggatgc caccggacag
    20821 ctccaccttc acgtccagct tgccgaccac ctcggccagc agcgcggcgt tggagccccg
    20881 cccgaacgcg gcgtccagat ccaccagatg gatccactcc gcgccgtcgg actgccaggc
    20941 cagcgccgcg t
//
