LOCUS       NZ_CP118233            24534 bp    DNA     circular CON 13-JUL-2024
DEFINITION  Micromonospora chalcea strain 1K05785M01 chromosome, complete
            genome.
ACCESSION   NZ_CP118233
VERSION     NZ_CP118233.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora chalcea
  ORGANISM  Micromonospora chalcea
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Study on the Growth Characteristics and Drug Resistance Related
            Proteins of Micromonospora chalcea MCCC 1K05785
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2023) Tianjin University, Tianjin University,
            Weijinlu Nub92, Tianjin, Tianjin 300072, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2022
            Assembly Method                   :: CLC NGS Cell v. 5.29
            Assembly Name                     :: TJU-micro-1.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028768405.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 23:01:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,224
            CDSs (total)                      :: 6,161
            Genes (coding)                    :: 6,110
            CDSs (with protein)               :: 6,110
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 51
            CDSs (without protein)            :: 51
            Pseudo Genes (ambiguous residues) :: 0 of 51
            Pseudo Genes (frameshifted)       :: 16 of 51
            Pseudo Genes (incomplete)         :: 40 of 51
            Pseudo Genes (internal stop)      :: 2 of 51
            Pseudo Genes (multiple problems)  :: 7 of 51
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:37:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2727521
            Orig. end                         :: 2752055
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP118233.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24534
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="terpene"
                     /product="RiPP-like"
                     /region_number="16"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24534
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="neighbouring"
                     /product="terpene"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22420
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22420
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12420](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12420)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(60..75)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.81"
                     /tool="antismash"
     misc_feature    complement(87..101)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 20.76"
                     /tool="antismash"
     misc_feature    complement(180..194)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.24"
                     /tool="antismash"
     misc_feature    197..217
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.57"
                     /tool="antismash"
     gene            202..1170
                     /db_xref="GeneID:91356778"
                     /locus_tag="PVK74_RS11465"
                     /old_locus_tag="PVK74_11465"
     CDS             202..1170
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287407.1"
                     /locus_tag="PVK74_RS11465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11465"
                     /product="trypsin-like serine protease"
                     /protein_id="WP_043329682.1"
                     /transl_table=11
                     /translation="MKTTIRLLALPALILPTILAGTPAQAATDTTSGTAAPAAVTSIER
                     KVGSSAGQARAYWTAERMAAATPADEVEKAAGPVTQSPTAERVRRFAEAVAPKDGSGFG
                     AQLNESITVGKIFYTSSTDGLGHYCSASVVNSPARNMVFTAAHCVHDGPGRDWHTANWM
                     FVPSYRNGAQPYGTWDWSTLAVPSGWISTRERQYDVAVALVYGSRSIVDAVGANGLLTG
                     GGRAYHYDVFGYPSNKDSGEIQWVCSGTSRDAGSNRIEMNCGFGGGSSGGPWYYSYDNT
                     TRRGDVHGVMSYSSGTNTNGSPYFSAAVVGTLYNTYANDTW"
     misc_feature    complement(203..217)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.52"
                     /tool="antismash"
     gene            1229..1435
                     /db_xref="GeneID:91356779"
                     /locus_tag="PVK74_RS11470"
                     /old_locus_tag="PVK74_11470"
     CDS             1229..1435
                     /codon_start=1
                     /db_xref="GeneID:91356779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287408.1"
                     /locus_tag="PVK74_RS11470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11470"
                     /product="hypothetical protein"
                     /protein_id="WP_064445329.1"
                     /transl_table=11
                     /translation="MSHRVLLGAAAVAALAVAVAVVVVAARDGGAGRPAPPGPVVATHN
                     PSPGATDPSEYWTRERMRDAIGD"
     gene            complement(1545..1775)
                     /db_xref="GeneID:91356780"
                     /locus_tag="PVK74_RS11475"
                     /old_locus_tag="PVK74_11475"
     CDS             complement(1545..1775)
                     /codon_start=1
                     /db_xref="GeneID:91356780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475917.1"
                     /locus_tag="PVK74_RS11475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11475"
                     /product="hypothetical protein"
                     /protein_id="WP_043329678.1"
                     /transl_table=11
                     /translation="MPLLRIHLDSDPTTARRVLQTHREGGVHHESREAAREQVWRQGRT
                     PAGDPVFVGITNGRRNVQLLYDVEVYSDTVP"
     gene            complement(1832..2236)
                     /db_xref="GeneID:91356781"
                     /locus_tag="PVK74_RS11480"
                     /old_locus_tag="PVK74_11480"
     CDS             complement(1832..2236)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (8-130). E-value:
                     4.1e-10. Score: 32.2. Matches aSDomain:
                     nrpspksdomains_PVK74_RS11480_Polyketide_cyc2.1"
                     /codon_start=1
                     /db_xref="GeneID:91356781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287409.1"
                     /locus_tag="PVK74_RS11480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11480"
                     /product="SRPBCC family protein"
                     /protein_id="WP_043329676.1"
                     /transl_table=11
                     /translation="MATDTRHLAVHIDRPVAEVYAFAADPANLPRWAPGLGGSVNLIDG
                     QWFVDTPEGRARLTFAPANEYGVLDHEVRTPSGETVYVPLRAIADGNATEVVFSLRRMP
                     GMSDTDFDRDTALVEADLARLKAVLESAAG"
     aSDomain        complement(1847..2212)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PVK74_RS11480_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="4.10E-10"
                     /label="PVK74_RS11480_Polyketide_cyc2.1"
                     /locus_tag="PVK74_RS11480"
                     /protein_end="130"
                     /protein_start="8"
                     /score="32.2"
                     /tool="antismash"
                     /translation="AVHIDRPVAEVYAFAADPANLPRWAPGLGGSVNLIDGQWFVDTPE
                     GRARLTFAPANEYGVLDHEVRTPSGETVYVPLRAIADGNATEVVFSLRRMPGMSDTDFD
                     RDTALVEADLARLKAVLE"
     misc_feature    complement(2316..2330)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.02"
                     /tool="antismash"
     gene            2321..2791
                     /db_xref="GeneID:91356782"
                     /locus_tag="PVK74_RS11485"
                     /old_locus_tag="PVK74_11485"
     CDS             2321..2791
                     /codon_start=1
                     /db_xref="GeneID:91356782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287410.1"
                     /locus_tag="PVK74_RS11485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11485"
                     /product="YfbM family protein"
                     /protein_id="WP_205797677.1"
                     /transl_table=11
                     /translation="MIFNARRLSAEELAAVLADPEKVDTLFQGGPDELDLDKAWHGLHY
                     LLTGDTYEIRGDAGPAVLGGDPIGPDLGMGPARLLMPDAVRAVAGGLDAIDEATLRARF
                     DPAALSEAEIYPHIWDDGADEFDAYLLPNFTALRDFYRAAAEQGDGMLLAIT"
     gene            2871..3647
                     /db_xref="GeneID:91356783"
                     /locus_tag="PVK74_RS11490"
                     /old_locus_tag="PVK74_11490"
     CDS             2871..3647
                     /codon_start=1
                     /db_xref="GeneID:91356783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475913.1"
                     /locus_tag="PVK74_RS11490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11490"
                     /product="hypothetical protein"
                     /protein_id="WP_274479055.1"
                     /transl_table=11
                     /translation="MGLDAFVYCRCWQDGLTTPCPVGPVGIDEDGCLALLRQWEGNEAA
                     HRTFDAWLAEACPHKAMEQASEHVSNWAGVRLFQQALRAAGPERFPTLATALPNLNGGS
                     LPADRAAVALAELDAFARTDRITDGVELIDEATGRVLMQYVESYHGVFMLGPDFRAGVD
                     PDGFFVVDTADPPVTLFRAVRFGQRPLPGDRVELTAGGTRTVLAMLPVGAHGEPPPERL
                     AVRTRSRSGSDFAYIVEPLRRLCAASVATGNPVMWF"
     misc_feature    complement(2883..2894)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 21.4"
                     /tool="antismash"
     gene            complement(3795..4526)
                     /db_xref="GeneID:91356784"
                     /locus_tag="PVK74_RS11495"
                     /old_locus_tag="PVK74_11495"
     CDS             complement(3795..4526)
                     /codon_start=1
                     /db_xref="GeneID:91356784"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475912.1"
                     /locus_tag="PVK74_RS11495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11495"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_064445325.1"
                     /transl_table=11
                     /translation="MSERTIALVTGANKGIGYEIAAGLGALGWRVGVGARDERRLAEAV
                     AKLRAGGVDAFGVPLDVTDDASVTAAARLLETEAGGLDVLVNNAGVTGGVPQHPGDVDL
                     ATIRTAVEVNVIGVVRVTEAMLPLLRRSASPRIVNMSSGVGSLTRQSASTGEDQTGPLS
                     VAYSPSKSMLNAVTIQYARALADTGILINAACPGFTATDLNSFRGVRTPQQGAAIAIRL
                     ATLPDDGPTGGYFEDAGTIPW"
     gene            4622..5470
                     /db_xref="GeneID:91356785"
                     /locus_tag="PVK74_RS11500"
                     /old_locus_tag="PVK74_11500"
     CDS             4622..5470
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356785"
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788263.1"
                     /locus_tag="PVK74_RS11500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11500"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_043329670.1"
                     /transl_table=11
                     /translation="METRELRYFVAVAEELHFGRAARRLGIAQPPLSRAIRQLERRLGV
                     TLLERDSRSVALTAAGSVLLREGRAALDAVAAADRRTRRAGQAATGGPGLVLATKTGAS
                     SELLPKLLGAYAAEPDAVPVEVLLCGIGEQERLLRDGRADVALLHLPYDSTTGLDTEEL
                     ITEPQVAILPAGHPLARRPHLLMAEVEALPGLPMPRWPRADGSYPDGPGPEVRDHAQLF
                     QLIALGRTVVVLPESARSLLLADLATVPVPDAPAVTTVIAWPPHSRSRALAGLIRTATR
                     L"
     gene            complement(5480..5962)
                     /db_xref="GeneID:91356786"
                     /locus_tag="PVK74_RS11505"
                     /old_locus_tag="PVK74_11505"
     CDS             complement(5480..5962)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788262.1"
                     /locus_tag="PVK74_RS11505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11505"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_064445324.1"
                     /transl_table=11
                     /translation="MTELSVRAMSPEEFDSWQDELAAGYAREHVTAGNWTPEEALDRAR
                     EATAGFLPQGMATPGMLFLVGELADGSPVGWLWIGLTHPRGLADCAFLYDIEVAAGHRG
                     RGLGRALLAAGERAAREHGAQALELNVFGTNETARKLYETSGYRVVTQQMRKDLPA"
     gene            complement(5974..6582)
                     /db_xref="GeneID:91356787"
                     /locus_tag="PVK74_RS11510"
                     /old_locus_tag="PVK74_11510"
     CDS             complement(5974..6582)
                     /codon_start=1
                     /db_xref="GeneID:91356787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287415.1"
                     /locus_tag="PVK74_RS11510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11510"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_043329666.1"
                     /transl_table=11
                     /translation="MDYGRSERPAGAGPLPTAIKILIAGGFGVGKTTMVGAVSETKPLR
                     TEEVLTETGIGIDDLSGVEEKSTTTVAMDFGRITISDDLVLYLFGTPGQDRFWFVWDEL
                     ALGALGAVVLADTRRLADCFPSIDYFEGRGTPFVVAVNCFEGAKKFRLDEVQAALDLDP
                     GVPVVLCDARKRESAKEVLITLLEHAMKLREARRRAAGD"
     gene            complement(6563..6952)
                     /db_xref="GeneID:91356788"
                     /locus_tag="PVK74_RS11515"
                     /old_locus_tag="PVK74_11515"
     CDS             complement(6563..6952)
                     /codon_start=1
                     /db_xref="GeneID:91356788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287416.1"
                     /locus_tag="PVK74_RS11515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11515"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_030503284.1"
                     /transl_table=11
                     /translation="MTGRGESAEQEWVDDHAGPVVRPYAVTGGRARPVTGTFDLISLVT
                     ATRTDVGSESGLGPEHVAIVGLCQRILSVAEIAAHLDLPVGTVRVLLGDLAARSLVQVR
                     EPRATTAGLPDEHVFEAVINGLRAL"
     gene            complement(6949..7374)
                     /db_xref="GeneID:91356789"
                     /locus_tag="PVK74_RS11520"
                     /old_locus_tag="PVK74_11520"
     CDS             complement(6949..7374)
                     /codon_start=1
                     /db_xref="GeneID:91356789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788260.1"
                     /locus_tag="PVK74_RS11520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11520"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_030503283.1"
                     /transl_table=11
                     /translation="MAQKTASSADLTWLLDDLVGRVKQAEHAVALSTDGLLMASSRGLS
                     RDDGEHLAAMAAGIQSLARGAGKRFGGGQVQQTIIEMQSSFLFVTAAGRNACLAVLASE
                     DADVGLIAYEMAMLVTRVGRFVASPTREQPLGENAAR"
     gene            complement(7440..9920)
                     /db_xref="GeneID:91356790"
                     /locus_tag="PVK74_RS11525"
                     /old_locus_tag="PVK74_11525"
     CDS             complement(7440..9920)
                     /codon_start=1
                     /db_xref="GeneID:91356790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287418.1"
                     /locus_tag="PVK74_RS11525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11525"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_274479056.1"
                     /transl_table=11
                     /translation="MGSRSTNLRTKIIALLASLTALWAFAAWVTVRDGFNLLGVQTLNA
                     RVFEPSDPLLQELQAERRLSLRYLGESDPGRLRELDAQRARTDETATALWRSVQDWRTE
                     IPASEELMQRLGELKTELDQIGQVRADVSRKTIDRTATLIAYDEAVDAIFAVFDALGGL
                     DDDEIAKDTAALIDLNRSRELLSQQDALITGAIAANRITVAEQTAFARLVGAQWFLADR
                     TARELAPTDRARFERMVEGDAFQQLQTLQDRVLAAKGADVRPPVTAAAWQAAAEQAMAD
                     LRGVILAGGEDIVSRAMPVAIGVIVRLVLAAGLGLLAVIASVVVSITTARSLVRQLERL
                     REAAFNLAHERLPSVVERLGRGDEVDVAREAPPLQFGDDEIGQVGKAFNVVQETAVRTA
                     VEQAELRRSVRDVFLSLARRTQALVHRQLTLLDAMERREHDAEELEDLFRVDHLATRMR
                     RNAENLIVLSGSTPGRAWRRNVPMVDVVRGAVAEVEDYTRVTVRPLGEVSLTGRAVGDV
                     IHLLAELIENGLSFSPPQTTVEVRGQLVANGFAIEIEDRGLGMSPDELAAANARIVDRS
                     ELNLADAARLGLFVVSRLTERHGVKVQLKESAYGGTTAVVLIPRELITADGADAAEALP
                     APGTALPVAPAPDPVRSTPAGDGPAIPSGPDGAAEPDQPAEPAPQVPEPVTRAPRLTPS
                     GLPARTRKRQPAVAGPTTELAVVERRPAATTDAAEASPATEPETEAETTPVTDAGLPVR
                     VRQASLAPELRHDQTEADDDAADDDTARAPEQVRRMMSSYQSGTRRGRTDAARLLGGAQ
                     GAGGAPADADEQVT"
     gene            complement(10001..11548)
                     /db_xref="GeneID:91356791"
                     /locus_tag="PVK74_RS11530"
                     /old_locus_tag="PVK74_11530"
     CDS             complement(10001..11548)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356791"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287419.1"
                     /locus_tag="PVK74_RS11530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11530"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_064445322.1"
                     /sec_met_domain="T2TS (E-value: 3.1e-88, bitscore: 295.1,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLTAGSVPATRSGTAHDLVAALTGEPAGQTSPSVYETARLVALA
                     PWLDGHDRRLAWLLARQRPDGGWGGPGGYALVPTLSAVEALLTVLRRDGPAAVPAAAAH
                     RGLTFLSGALRGDAPPDLPATDLIVPALLTAVDRHLTGPAGPPPGLAEWAGRPRLPLPA
                     GLDPARLTRVRALLAAGRPVPEKLAHALEVAGELAYRAAGVRPSASGAVGASPAATAAW
                     LGRPEPGAALDYLRAVARPGPVPCASPITVFERAWVLGILVRAGVPVGAPEPVLTELRA
                     AVGPSGAATAPGLPADADTTAVTLYALARLGRAPGVGPLAGFDTGRHFCTWPGEDGASL
                     TTNAHVLDALGEQPSGPGVTGARRRVTEWLVERQQPDGRWEDRWHASACYATYAVLLAL
                     ADHAPDGTARAAVERGVAWLLDTQRPDGSWGLWHGTAEETAYAVLALAGAGRSGDARIA
                     AALARGRRRLSELDGCDDEPALWHDKDLYRPTQIVRAAVLAASGRAVEAGPTMIRIA"
     gene            complement(11545..12420)
                     /db_xref="GeneID:91356792"
                     /locus_tag="PVK74_RS11535"
                     /old_locus_tag="PVK74_11535"
     CDS             complement(11545..12420)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356792"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287420.1"
                     /locus_tag="PVK74_RS11535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11535"
                     /product="terpene synthase family protein"
                     /protein_id="WP_064445321.1"
                     /sec_met_domain="T1TS (E-value: 7.4e-11, bitscore: 40.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDGPTPDLLAVAAEQGRVCALAAQGQRGLRKAAAAHPELFPADP
                     FDATLFSSIAQAMAFSAPWHSAAELAVTNRAVLWGFAVDWLVDHQATSRAEVDRITGVC
                     LDVLDGAGTDDPLGRFLAELRDDVAAAPGYPALRGHWRAAMERTLDAMAREWDWRRTGR
                     PTLADYLANADNLAATVVNVAHWIHTGSVSTAEAMDHAVAVSDEVQRALRLVNDLGTHR
                     RDAESGDLNALLLVDDPAEVERRFAEQVDHCRVRLAKLAGEAPREADFLSRQLGFTTGF
                     YRNTDFWGVR"
     misc_feature    complement(12394..12396)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12417..13754)
                     /db_xref="GeneID:91356793"
                     /locus_tag="PVK74_RS11540"
                     /old_locus_tag="PVK74_11540"
     CDS             complement(12417..13754)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356793"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788256.1"
                     /locus_tag="PVK74_RS11540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11540"
                     /product="cytochrome P450"
                     /protein_id="WP_176722849.1"
                     /sec_met_domain="p450 (E-value: 3.5e-72, bitscore: 242.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLRQILPAVLRDPARALIDIGNRTEGELVRLNLGSFRPYLVTHP
                     KHVQHVLRDRADNYERAGDGLFWRPVKRLFGEGILGEGQIWSASRRMLQPMFTAKRVEA
                     LVDGMADAIRDAVDELDEPARAGRPVDIGVEQARIVSRAIMKVLFADRISVPDAMRVIE
                     AQDRIATAVIPRIIVPFAPLSLPMPGDRTFARAVRIVDDVLVPIVRETRESADQGDDVI
                     STLWQARTDDGRQLDERQVRNDTVAMFAATTETTINVLTWAWPHLDQHPEVAERLYAEI
                     DEVVGGEPVRREHLSRLTYTRMVLDELLRLYPIGWIIPRRAVAGDVIDGVPIEPGATMA
                     VSPLITQRMRQFWDRPDEFDPERFRPERVRARHRYAHFPFGGGPHQCLGMYLFYLEAQL
                     ILATMLSRYRFRLHRPGVPGLRLAAALRPRERVELTLVAAGRAERA"
     cand_cluster    13716..24534
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    13716..24534
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[18715:19534](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      18716..19534
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
     misc_feature    13909..13922
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.03"
                     /tool="antismash"
     misc_feature    complement(13909..13925)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.16"
                     /tool="antismash"
     gene            14066..14314
                     /db_xref="GeneID:91356794"
                     /locus_tag="PVK74_RS11545"
                     /old_locus_tag="PVK74_11545"
     CDS             14066..14314
                     /codon_start=1
                     /db_xref="GeneID:91356794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287422.1"
                     /locus_tag="PVK74_RS11545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11545"
                     /product="DUF2630 family protein"
                     /protein_id="WP_030503278.1"
                     /transl_table=11
                     /translation="MDDKTILSRISELVDEEHRLRADAQQHESGTDDEARERLRALEES
                     LDQCWDLLRRRRAARQAHGDPDAQGERPVPEVERYLQ"
     gene            complement(14366..15292)
                     /db_xref="GeneID:91356795"
                     /locus_tag="PVK74_RS11550"
                     /old_locus_tag="PVK74_11550"
     CDS             complement(14366..15292)
                     /codon_start=1
                     /db_xref="GeneID:91356795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018583044.1"
                     /locus_tag="PVK74_RS11550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11550"
                     /product="RIO1 family regulatory kinase/ATPase"
                     /protein_id="WP_043329659.1"
                     /transl_table=11
                     /translation="MRDHDFPAPQRRGRGKSRFDDDETDFLKRGRPTPTLADPDAEPDA
                     EDSWSSWDRAVHGPEPYPDWLVTELAARDTELGVLKTGKEADVHLVRRAVPDTDRSCLL
                     AVKRYRDAQHRLFHRDAGYLEGRRVRRSREMRAMTGRTAFGRQMIAGQWAAAEFAALSQ
                     LWEIGAASGRIAVPYPVQLLGTELMLEFVGDAEAGEAAPRLAQVRPDAAELRDLWDQLV
                     EALTVLARAGYAHGDLSPYNLLVHAGRLVMIDLPQVVDVVANPQGGEFLGRDVRVVAAW
                     FAARGMPATVTDPEALTEALLREAGIR"
     gene            complement(15491..16135)
                     /db_xref="GeneID:91356796"
                     /locus_tag="PVK74_RS11555"
                     /old_locus_tag="PVK74_11555"
     CDS             complement(15491..16135)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356796"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287424.1"
                     /locus_tag="PVK74_RS11555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11555"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_030503276.1"
                     /sec_met_domain="HAD_2 (E-value: 1.1e-11, bitscore: 43.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLLLLDLDNTLLDRDGPFRVWGERFLAGIGAPPADLDWLVSVDA
                     DGLTNRWDVADAIRDRYALRIPSIDLVDELHDGVVAHMRLDPLVACALRIAADAGWVPV
                     VVTNGASRQQDAKIRKTGLDRYVADWVISEEAGVSKPNPRIFALAAQRARMPLRGAWVV
                     GDSPEADIGGATAVGLPSVWLHRGRRWSDPRFAPTRIEDGLIAAVAAVLAG"
     gene            complement(16192..17037)
                     /db_xref="GeneID:91356797"
                     /locus_tag="PVK74_RS11560"
                     /old_locus_tag="PVK74_11560"
     CDS             complement(16192..17037)
                     /codon_start=1
                     /db_xref="GeneID:91356797"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287425.1"
                     /locus_tag="PVK74_RS11560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11560"
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="WP_274479057.1"
                     /transl_table=11
                     /translation="MTALPARPLTVAAVQAQPVPGDVAGNARAAARLVARAEGARVVVL
                     PELFLPAYHPPTLGADPEGTDVAADADGRVADPRLDPLRTAAADAGAAVVIGAAVRHPD
                     RRRTISSLVVDPAGTVTAAYDKQQLWSGEREMFDAGRRGATLDVDTWRFGLGVCYDGCF
                     PEHARAAAGDGAHGYLCPSGYLAGSEHRRDLYYAARALDNTMYVVFANVVGGADPWRFN
                     GGAAVYDPEGRPLARGADTGEDVLVATLDPEALAATRAAHTMLLDRPVDAGAARTALVA
                     "
     gene            17142..17714
                     /db_xref="GeneID:91356798"
                     /locus_tag="PVK74_RS11565"
                     /old_locus_tag="PVK74_11565"
     CDS             17142..17714
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356798"
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788252.1"
                     /locus_tag="PVK74_RS11565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11565"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_030503274.1"
                     /transl_table=11
                     /translation="MPRVSQDQLDARRQEILAAARACFARHGYEGATVRRLEEATGLSR
                     GAIFHHFRDKDSLFLAVAEDDAAAMVETVARNGLVQVMRDLLARAVSPDTTGWLGSQLE
                     VSRRLRTDPAFAKRWAERSEAIAAATRERLVRQREAGVLRDDVPIDVLAQFLELAYDGL
                     VLHLAMGRPAGDLARVLDLVEEAVRRH"
     gene            17817..18719
                     /db_xref="GeneID:91356799"
                     /locus_tag="PVK74_RS11570"
                     /old_locus_tag="PVK74_11570"
     CDS             17817..18719
                     /codon_start=1
                     /db_xref="GeneID:91356799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475902.1"
                     /locus_tag="PVK74_RS11570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11570"
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_274479058.1"
                     /transl_table=11
                     /translation="MTPSDTWGIPGPVFLRWYLLLAVVLVIGAIVYRRRMLAGTPVTDH
                     GTLGPQQVAYLNGGDQLAVWATLGALRHAGAVGVRPDRRLTTGGPLPAGATPLDQAVHH
                     AASRGLRTRDLAADEWVRRALDELRDGLVRRGLALDQERRRTLRRGALLIGFLLAIGVV
                     RAISGLLNDRPTGWLLLSLFPLGLAFLLLNRVPWRTRAATAALNDMRRRHAWLRPAASP
                     AYATYGATDVALGVALFGTATLWTMDPGFAEQAEIQRQAMGNVGGASSGTSCGGGASTC
                     GGGSSCGGGGGCGGGGCGG"
     gene            18716..19534
                     /db_xref="GeneID:91356800"
                     /locus_tag="PVK74_RS11575"
                     /old_locus_tag="PVK74_11575"
     CDS             18716..19534
                     /codon_start=1
                     /db_xref="GeneID:91356800"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018802926.1"
                     /locus_tag="PVK74_RS11575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11575"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_274479059.1"
                     /sec_met_domain="DUF692 (E-value: 3e-76, bitscore: 254.7,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGPSGVGIGWRPEIAGFVAGLPGLRFVEVVAEAVAPAGPLPDGL
                     AELRGRGVDVVPHGVRLSLGGAEPVDPARVAHLAAVAAALDAPLVSEHIAFVRAGGLEA
                     GHLLPLPRSREAVAAVVANVRRTQAELPVPLALEPIAALFDWPDDELDEADFLTEILDA
                     TGALLLLDVANVHANARNRGGEPTALLDRLPLERIAYAHVAGGAEHGGFYHDTHTDPVP
                     AAVLDLVRELCRRRRPPALLLERDGHYPPAAELRAELDALAAASGHPAVT"
     gene            19531..19977
                     /db_xref="GeneID:91356801"
                     /locus_tag="PVK74_RS11580"
                     /old_locus_tag="PVK74_11580"
     CDS             19531..19977
                     /codon_start=1
                     /db_xref="GeneID:91356801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788249.1"
                     /locus_tag="PVK74_RS11580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11580"
                     /product="hypothetical protein"
                     /protein_id="WP_274479060.1"
                     /transl_table=11
                     /translation="MSGDLAARQAELVAALVAGGPLPPGFAPAPVEAARRALLRKRAAD
                     VARHWPLLAAGLGAHWPATFTAWADGRPSNGSLRDGWDLARELRDRGTLPPLGAEELAA
                     REVASRYDGHRPPRPRRMPAVARAGGAVAAQFAGRVRLLRPAPR"
     gene            20010..20771
                     /db_xref="GeneID:91356802"
                     /locus_tag="PVK74_RS11585"
                     /old_locus_tag="PVK74_11585"
     CDS             20010..20771
                     /NRPS_PKS="Domain: PKS_KR (8-127). E-value: 2.9e-09. Score:
                     29.0. Matches aSDomain:
                     nrpspksdomains_PVK74_RS11585_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GeneID:91356802"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018815297.1"
                     /locus_tag="PVK74_RS11585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11585"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_069089101.1"
                     /transl_table=11
                     /translation="MDLGLADRVYVLTGASGGLGFATAEQLVADGARVVISARTPERVA
                     AAIEALGDPQRAIGLTADLADSATPERLVAAAREHFGRLDGALISVGGPPPGTAATVTD
                     EQWRESFETVFLGSVRLARTVAGALTDGGAIGLVLSTSVRGPLAGLGISNGLRPGLAGV
                     AKDMADEFGPRGVRVVSLLPGRIMTDRNRELLAGSGDPERARAQAEAAIPLGRIGDPAE
                     FGRVAAFLLSPAAGYVTGVTVPVDGGALRGL"
     CDS_motif       20034..20117
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PVK74_RS11585_0001"
                     /evalue="1.20E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="PVK74_RS11585"
                     /protein_end="36"
                     /protein_start="8"
                     /score="27.6"
                     /tool="antismash"
                     /translation="VYVLTGASGGLGFATAEQLVADGARVVI"
     aSDomain        20034..20390
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PVK74_RS11585_PKS_KR.1"
                     /evalue="2.90E-09"
                     /label="PVK74_RS11585_PKS_KR.1"
                     /locus_tag="PVK74_RS11585"
                     /protein_end="127"
                     /protein_start="8"
                     /score="29.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VYVLTGASGGLGFATAEQLVADGARVVISARTPERVAAAIEALGD
                     PQRAIGLTADLADSATPERLVAAAREHFGRLDGALISVGGPPPGTAATVTDEQWRESFE
                     TVFLGSVRLARTVAG"
     gene            20815..21435
                     /db_xref="GeneID:91356803"
                     /gene="mug"
                     /locus_tag="PVK74_RS11590"
                     /old_locus_tag="PVK74_11590"
     CDS             20815..21435
                     /EC_number="3.2.2.28"
                     /GO_function="GO:0000700 - mismatch base pair DNA
                     N-glycosylase activity [Evidence IEA]"
                     /GO_process="GO:0006285 - base-excision repair, AP site
                     formation [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356803"
                     /gene="mug"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287431.1"
                     /locus_tag="PVK74_RS11590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11590"
                     /product="G/U mismatch-specific DNA glycosylase"
                     /protein_id="WP_140946398.1"
                     /transl_table=11
                     /translation="MSDRRRPGGGRPEAAPGPGTPARRHPRPSREQLAAAADRLLPDVI
                     APGLDVLFVGINPGLWSAATGWHFARPGNRFWPALHRGGFTPRLLHPSEQDALPALGLG
                     ITNMVARASARADELTAAELVDGAATLTAKVERYRPRWVAVVGVTAYRIGFTRPKAGFG
                     PQPETLGPARLWVLPNPSGLNAHFTPETLGAAFAELRAAVAAG"
     gene            complement(21562..23544)
                     /db_xref="GeneID:91356804"
                     /locus_tag="PVK74_RS11595"
                     /old_locus_tag="PVK74_11595"
     CDS             complement(21562..23544)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356804"
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019030577.1"
                     /locus_tag="PVK74_RS11595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11595"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_064445314.1"
                     /transl_table=11
                     /translation="MAGGGMGGWSMLRSLRNRDEVSAHELKRGTARRIVAFARPYRRDI
                     VVFLITVIIAAVIGVATPLLAGDVIDAIAGGGPDARTTVVRLALIIAALAVADALFSLV
                     QRWYSARIGEGIILDLRTRVYDHVQRMPLQFFTRTQTGALVSRLNNDVLGAQRAFTSTL
                     SGVVSNVIQLVLTAGAMLVLSWQITVLALVLLPIFIIPARRVGRRLAEITRESYNLDAK
                     MNATMTERFGVAGALLVKLFGAPEVEADRFARRAERVRDIGIQSAMYSRTFFVAMLLVA
                     SLAQALTYGVGGWLAVTGAVSAGTVVKLALLLTRLYGPLTALSNVRVDVMSALVSFDRV
                     FEVLDLRPGIAEKPDAVPVPRGSGRVEFRDVRFRYPSAAEVSLASLEEVSTLDRTVNEP
                     VLKGVSFAVEPGQMVALVGPSGAGKSTLSMLISRIYDVSEGQVLVGGVDVRDATLASLR
                     DEIGVVTQDSHLFHETIRENLRYAKPDATDDEIWAALAGAQVADLVRALPDGLDTTVGE
                     RGYRFSGGEKQRIAIARLLLKAPSIVILDEATAHLDSESEAAVQRALSVALTGRTALVI
                     AHRLSTVRDADQILVLDEGRIVERGRHDELVAVGGLYAELYRTQFAVTDSPAPHAEAEQ
                     PEPVVTTVPMGTYVAHEAMPPAAAN"
     gene            complement(23680..24447)
                     /db_xref="GeneID:91356805"
                     /locus_tag="PVK74_RS11600"
                     /old_locus_tag="PVK74_11600"
     CDS             complement(23680..24447)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (13-244). E-value: 1.3e-44. Score:
                     144.3. Matches aSDomain:
                     nrpspksdomains_PVK74_RS11600_ECH.1"
                     /codon_start=1
                     /db_xref="GeneID:91356805"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018722897.1"
                     /locus_tag="PVK74_RS11600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11600"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_043329652.1"
                     /transl_table=11
                     /translation="MTAETTGVRFDCDGPVATVTLCRPDVLNAQTPAMWRAMSDFSRDL
                     PGDVRVVVVRGEGRAFSAGLDLAVAGATGPGSFAELAALPEAECADRIAEYQGGFTWLH
                     RPDVVSIAAVQGHAIGAGFQLALACDMRVLAADARLSMAEVTLGLVPDLAGTRRLVELV
                     GYSRALEICATGRRMDATEADRIGLATLVVPNDELDAAVRDLSAGLLANNRDAIVEIKA
                     LLAGAADRTHAEQQRAEREAQTRRIRDLAGRGE"
     aSDomain        complement(23716..24408)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PVK74_RS11600_ECH.1"
                     /evalue="1.30E-44"
                     /label="PVK74_RS11600_ECH.1"
                     /locus_tag="PVK74_RS11600"
                     /protein_end="244"
                     /protein_start="13"
                     /score="144.3"
                     /tool="antismash"
                     /translation="GPVATVTLCRPDVLNAQTPAMWRAMSDFSRDLPGDVRVVVVRGEG
                     RAFSAGLDLAVAGATGPGSFAELAALPEAECADRIAEYQGGFTWLHRPDVVSIAAVQGH
                     AIGAGFQLALACDMRVLAADARLSMAEVTLGLVPDLAGTRRLVELVGYSRALEICATGR
                     RMDATEADRIGLATLVVPNDELDAAVRDLSAGLLANNRDAIVEIKALLAGAADRTHAEQ
                     QRAEREAQT"
ORIGIN
        1 ccgaggtcga gcgccgctca cggacccgga attgcaattc gatgatgtcc ccgccctccc
       61 cgatcacaca tccgacaccg caaacaatcg acgtccatga ttcattgaca cgctccgaat
      121 cccgtcgata cgttgccgac atcgcgatga acaacggggc gctccagttt cgatccggaa
      181 tcgaaaactg ggaaggattt catgaagacg acgatcagac ttctggccct gccggccctg
      241 atcctgccga cgatcctcgc cggcactccg gctcaggccg ccaccgacac cacctccggc
      301 accgccgctc cggccgcggt gacctcgatc gagcgcaagg tggggtcgtc ggccgggcag
      361 gccagggcat actggacggc cgagcggatg gcggcggcca ctcccgccga cgaggtggag
      421 aaggccgccg gcccggtcac ccagagcccc acggcggagc gggtacggcg cttcgcggag
      481 gcggtggcgc cgaaggacgg cagcggcttc ggcgcccagc tcaacgagtc gatcacggtg
      541 gggaagatct tctacaccag ctcgaccgac ggcctgggcc attactgctc ggcgagcgtg
      601 gtgaacagcc cggcgcgcaa catggtcttc accgccgcgc actgcgtgca cgacgggccg
      661 ggccgggact ggcacaccgc gaactggatg ttcgtgccgt cctaccgcaa cggcgcgcag
      721 ccgtacggca cctgggactg gtccacgctc gcggtgccca gcggctggat cagcacccgc
      781 gagcggcagt acgacgtggc ggtcgcgctc gtctacggca gccggtcgat cgtggacgcg
      841 gtcggcgcga acggcctgct caccggcggt gggcgcgcgt accactacga cgtcttcggc
      901 tacccgagca acaaggacag cggcgagatc cagtgggtct gctcgggcac gtcgagggac
      961 gcgggcagca accggatcga gatgaactgc ggcttcgggg gcggttcgag cggcggcccg
     1021 tggtactaca gctatgacaa caccaccagg cgcggtgacg tgcacggggt gatgagctac
     1081 tcgagcggca cgaacacgaa cggctcgccg tacttctccg ccgcggtggt ggggacgctc
     1141 tacaacacgt acgcgaacga cacctggtga acgacggtcc gcctggtgtg ccgccggcgc
     1201 accggtcgac cggtccggag gaggcgacat gtcacatcgt gtactgctcg gcgcggccgc
     1261 cgtcgcggcg ctcgccgtgg ctgtggccgt cgtggtcgtc gcggcgcgcg acggcggcgc
     1321 ggggcggccg gcgccgcccg gcccggtggt cgcgacccac aatccgagcc cgggtgccac
     1381 cgacccgtcc gaatactgga cgagggaacg aatgcgggac gcgatcggcg actgaatcaa
     1441 gaattgcatt cggcgcccag gtgcgtcgaa tttcgtcccg ctcacgatca ccggccgagc
     1501 ccggcgcgca attcccattt caggggcgtg agtgccgcgt gcgttcacgg gacggtatcg
     1561 gagtagacct cgacgtcgta gagcagttgc acgttgcggc gtccgttggt gatgccgacg
     1621 aagaccgggt caccggccgg ggtgcggccc tggcgccaca cctgctcccg ggccgcttcc
     1681 cgcgactcgt gatgcacgcc gccctcgcga tgcgtctgca ggacgcggcg ggcggtggtc
     1741 gggtcgctgt cgaggtggat ccgcagcagg ggcatgacgc gccctccttg ccactgtcgg
     1801 ggccggactg ccgactgacc acgcgcgcct ctcagccggc ggcgctctcc agcacggcct
     1861 tgagccgggc cagatccgcc tcgaccagcg cggtgtcccg gtcgaagtcc gtgtcgctca
     1921 tgccgggcat ccggcgcagg ctgaacacca cctcggtggc gttgccgtcg gcgatggcgc
     1981 gcaacggcac gtacaccgtc tcgcccgacg gcgtccgcac ctcgtggtcg agcacgccgt
     2041 actcgttggc cggggcgaac gtgagccgcg cccgcccttc gggtgtgtcc acgaaccact
     2101 ggccgtcgat gaggttcacc gaaccgccga ggcccggcgc ccagcggggc aggttcgccg
     2161 ggtcggcggc gaaggcgtag acctccgcga ccggacggtc gatgtggacg gcgaggtggc
     2221 gggtgtcagt ggccatgcgc cgatggtgcc atgcctgtcg caagcgcacg ctacgctgcc
     2281 gccgattccg accggcaccc ctgagaggca ccccgtgggc atgatcttca acgcacgccg
     2341 gctgtccgcc gaggagctgg cggcggtcct cgccgacccg gagaaggtcg acaccctgtt
     2401 ccagggtggc ccggacgagc tcgacctcga caaggcgtgg cacgggctgc actacctact
     2461 gaccggcgac acgtacgaga tccggggcga cgccgggccg gccgtcctgg gtggtgaccc
     2521 gatcgggccg gacctgggga tgggcccggc ccggctgctg atgcccgacg ccgtccgcgc
     2581 tgtggccggc gggctcgacg cgatcgacga ggcgacgctg cgggcccgct tcgacccggc
     2641 agccttgtcg gaggccgaga tctacccgca catctgggac gacggcgccg acgagttcga
     2701 cgcctacctg ctgccgaact tcaccgcgct gcgtgacttc taccgcgccg cggccgaaca
     2761 gggggacggc atgctgctcg ccatcacgtg acccgccgga agcgtgccta cggaagcggg
     2821 ccggcggaaa cgggtacgcg ccgacgatcg ggcgccggta gcgtgccggc gtgggactcg
     2881 acgcgttcgt gtactgccgg tgctggcagg acggcctcac cacgccgtgc ccggtcggac
     2941 cggtcggcat cgacgaggac ggctgtctcg cgctgttgcg gcagtgggag ggcaacgagg
     3001 ccgcgcaccg cacgttcgac gcctggctgg cggaggcgtg cccgcacaag gccatggagc
     3061 aggcgagcga gcacgtttcc aactgggccg gcgtacgcct gttccagcag gcgctacgcg
     3121 ccgccggccc ggagcgcttc ccgacgctcg ccaccgcgct gccgaacctc aacggcggct
     3181 cgctgccggc cgaccgggcg gcggtggcgc tcgccgagct ggacgcgttc gcgcgcaccg
     3241 atcggatcac cgacggggtc gaactgatcg acgaggcgac cggccgggtg ctgatgcagt
     3301 acgtcgagag ctaccacggg gtgttcatgc tcggcccgga cttccgggcc ggggtagatc
     3361 cggacggctt cttcgtcgtc gacaccgccg acccgccggt gacgctgttc cgggccgtcc
     3421 ggttcggcca gcggccgctg cccggcgacc gggtggagct caccgccggc gggacacgga
     3481 cggtgctggc gatgctgccg gtgggcgccc acggcgagcc gccgcccgaa cggctcgcgg
     3541 tgcggacccg gagccggtcg ggcagcgact tcgcctacat cgtggagccg ctgcgccggc
     3601 tgtgcgcggc gtcggtggcc accggcaacc cggtgatgtg gttctgacgg gccaccctcg
     3661 acagccggtc cgcaccgcgc tctgatggac caccgcatgt ccgggcgtgt cgtccgggga
     3721 aagatgacgt cacctgagag cggtataccc cgccgtgagc gtcacgctca gtcacgtcta
     3781 gaagctgacc ggagtcacca cgggatcgtg cccgcgtcct cgaagtagcc gccggtcggc
     3841 ccgtcgtcgg gcagcgtcgc gagccggatc gcgatcgccg cgccctgctg cggggtccgc
     3901 acaccgcgga agctgttgag gtcggtggcg gtgaagcccg ggcaggcggc gttgatcagg
     3961 atgccggtgt ccgccagcgc ccgcgcgtac tggatggtca ccgcgttgag catgctcttc
     4021 gacggcgagt acgccaccga cagcggcccg gtctggtcct ctccggtgga ggcgctctgc
     4081 cgggtcagcg agccgacacc gctggacatg ttgacgatcc ggggcgacgc cgagcggcgc
     4141 agcagcggca gcatcgcctc ggtcacccgg accaccccga tcacgttcac ctcgacggcg
     4201 gtccggatgg tcgcgaggtc gacgtcgccc gggtgctgcg gcacgccacc tgtcacgccc
     4261 gcgttgttga cgagcacgtc cagaccgccg gcctccgtct ccagcagccg ggcggcggcg
     4321 gtcacgctcg cgtcgtcggt gacgtccagc ggtacgccga acgcgtccac gccgcccgcg
     4381 cgcagcttcg ccaccgcctc ggcgagccgc cgctcgtccc gggcgccgac gcccacccgc
     4441 cagccgagcg cgcccaggcc ggccgcgatc tcgtacccga ttcccttgtt cgcgccggtc
     4501 accagcgcga tcgtccgttc gctcatgccc tcgatcctgt ccgcgggccg cgcgggcctc
     4561 caacaccgct tcggtggcgc gcgatacccg gaaggcatcg atgcggcggt acggtggcgg
     4621 gatggagacg cgggagcttc gctacttcgt ggcggtcgcc gaggagctgc acttcggccg
     4681 cgccgcgcgc cgcctgggca tcgcccagcc gccgctgtcg cgagcgatcc ggcagctcga
     4741 acgccgtctc ggcgtgactc tgctggagcg ggacagccgc agcgtcgcgc tcaccgcggc
     4801 cgggtcggtg ctgctgcggg agggccgggc cgcactcgac gccgtggccg ccgccgaccg
     4861 ccgcacccga cgcgccgggc aggccgctac cggtggcccc gggctggtgc tggcgaccaa
     4921 gaccggggcg tcgagcgagc tgctgccgaa actgctcggc gcgtacgccg ccgagccgga
     4981 cgcggtcccg gtcgaggttc tgctgtgcgg catcggcgag caggaacggc tgctgcgcga
     5041 cgggcgggcc gacgtggcgc tgctgcacct gccgtacgac tcgacgaccg ggctggacac
     5101 cgaagagctg atcaccgagc cgcaggtggc gatcctgccg gccgggcatc cgctggcccg
     5161 gcgaccgcac ctgctgatgg ccgaggtgga ggcgctgccg ggcctgccca tgccgcgctg
     5221 gccccgggcc gacgggtcgt atccggacgg gcccggcccc gaggtccggg accacgccca
     5281 gttgttccag ctcatcgcgc tcggccggac cgtggtggtg ctgccggagt cggcccggtc
     5341 gctgctgctc gccgacctgg ccaccgtgcc ggtgccggac gcgccggcgg tgaccacagt
     5401 catcgcgtgg ccaccgcaca gccggtcccg ggcgctggcc ggcctgatcc ggaccgccac
     5461 ccgcctctga cgctcgtgcc taggcgggca ggtccttgcg catctgctgg gtgaccaccc
     5521 ggtatcccga cgtctcgtac agcttgcgcg ccgtctcgtt ggtgccgaag acgttcagct
     5581 ccagcgcctg ggcgccgtgc tcccgggccg cccgctcccc cgccgcgagc agcgcccgcc
     5641 cgagcccccg gccccggtgc ccggcggcca cctcgatgtc gtagaggaac gcgcagtcgg
     5701 cgagaccgcg agggtgggtc aggccgatcc acagccagcc gaccggtgag ccgtcggcaa
     5761 gctcgccgac caggaacagc atgccgggcg tggccatgcc ctgcggcagg aagccggcgg
     5821 tggcctcccg ggcccggtcg agcgcctcct cgggcgtcca gttgccggcc gtgacgtgct
     5881 cgcgcgcgta cccggcggca agctcgtcct gccagctgtc gaactcctcc ggtgacatcg
     5941 cccggacact cagctcggtc atgcgacgca gcctcagtcg ccggcggcgc ggcggcgcgc
     6001 ctcgcgcagc ttcatggcgt gttccagcag cgtgatcagc acctccttgg ccgactcacg
     6061 cttgcgcgcg tcgcacagca ccacaggtac gcccgggtcc aggtcgagcg ccgcctgcac
     6121 ctcgtcgagc cggaacttct tggccccctc gaagcagttc accgccacca cgaacggcgt
     6181 gccgcgcccc tcgaagtagt cgatcgacgg gaagcagtcc gccaggcggc gcgtgtcggc
     6241 gagcaccacc gccccgagcg cgccgagcgc cagctcgtcc cagacgaacc agaaccggtc
     6301 ctgcccgggc gtgccgaaca ggtagagcac caggtcgtcg ctgatggtga tccggccgaa
     6361 gtccatcgcc acggtggtgg tcgacttctc ctccacgccg gacaggtcgt cgatgccgat
     6421 cccggtttcg gtaagcacct cctcggtgcg cagcggcttg gtctcgctga ccgcgcccac
     6481 catggtggtc ttgccgacgc cgaacccgcc cgcgatcagg atcttgatcg cggtgggcag
     6541 cggcccggcg cccgccggcc gctcagagcg cccgtagtcc attgataacc gcctcgaaaa
     6601 cgtgctcgtc gggaaggccg gcggtggtcg cgcgcggctc gcgtacctgc accagactgc
     6661 gggcggccag gtctccgagg aggacccgga ccgtgcccac cggcaggtcg agatgggcgg
     6721 cgatctcggc cacggagaga atccgctggc agaggccgac tatcgccacg tgctccgggc
     6781 ccagcccgga ctccgacccg acatccgtgc gggtcgcggt gaccagcgag atcaggtcga
     6841 acgtgccggt caccgggcgg gcccggccgc cggtgaccgc gtacgggcgc accaccgggc
     6901 cggcgtggtc gtccacccac tcctgctccg cggactcccc ccggccggtc atcgtgccgc
     6961 gttctcgccg aggggctgtt cccgggtcgg tgacgcgacg aaccggccga cccgggtgac
     7021 gagcatggcc atctcgtacg cgatcaggcc gacatccgcg tcctccgagg ccagcaccgc
     7081 caggcaggcg ttacgcccgg ccgctgtgac gaacaggaag gaggactgca tctcgatgat
     7141 ggtctgctgc acctgcccgc cgccgaaccg cttgcccgcg ccacgggcca ggctctggat
     7201 gcccgccgcc atggcggcca ggtgctcgcc gtcgtcccgg ctcaatccgc gggacgaggc
     7261 catcagcagt ccgtcggtgg agagcgccac ggcgtgctcc gcctgcttga cccggccgac
     7321 caggtcatcc agcagccacg tcagatccgc gctcgaagcc gtcttctgcg ccactcgtcg
     7381 tcctcttctt tccggctgtg tgccgtcagc ttccggtttc cgtcgcgtcg acgtcccggt
     7441 caggtaacct gctcgtccgc gtcggccggc gcaccgccgg ccccctgagc cccgccgagc
     7501 aggcgcgcgg catcggtacg gccgcgtcgg gtgccgctct ggtaggagct catcatccgg
     7561 cgcacctgct ccggtgcacg cgccgtgtca tcgtcggcgg cgtcgtcgtc cgcctcggtc
     7621 tggtcgtgcc gcagttccgg cgcgaggctg gcctggcgta cccggaccgg cagtcccgcg
     7681 tcggtgaccg gcgtcgtctc cgcctcggtc tccggctccg tcgccggcga cgcctccgcc
     7741 gcgtcggtcg tggcggcggg ccgccgctcc accaccgcca gctccgtggt gggcccggcc
     7801 accgcgggct gccgcttgcg ggtacgcgcc ggcagcccgg acggggtcag ccggggcgcc
     7861 cgcgtcaccg gctccggcac ctgcggggcg ggctcggccg gctggtccgg ttcggcggcg
     7921 ccgtccgggc cggacgggat cgccggcccg tcgccggccg gagtgctccg caccgggtcc
     7981 ggcgcgggcg ccacgggcag ggccgtcccg ggtgcgggaa gggcctcggc cgcgtcggcg
     8041 ccgtcagcgg tgatcagttc acgcgggatc agcaccacgg cggtggtccc gccgtacgcg
     8101 gattccttga gctgcacctt gacgccgtgc cgctcggtga gccggctgac cacgaacagg
     8161 cccagccggg cggcgtcggc caggttcagc tcggaccggt cgacgatgcg cgcgttggcg
     8221 gcggccagct cgtcggggct catgccgagg ccccggtcct cgatctcgat ggcgaagccg
     8281 ttcgccacga gctgaccgcg aacctcgaca gtggtctgcg gcggcgagaa ggagagcccg
     8341 ttctcgatca gctcggccag caggtggatg acgtcaccga cggcgcggcc ggtcagcgac
     8401 acctcgccga gtgggcgcac cgtgacccgg gtgtagtcct cgacctcggc taccgcgccg
     8461 cggaccacgt cgaccatcgg cacgttgcgt cgccaggccc ggccgggcgt ggagccggag
     8521 agcacgatca ggttctccgc gttgcgccgc atccgggtgg ccaggtggtc gacccggaac
     8581 aggtcctcca gctcctcggc gtcgtgttcc cggcgttcca tcgcgtccag cagcgtgagc
     8641 tgccggtgca cgagcgcctg ggtgcgccgg gccaggctga ggaagacgtc gcgtacgctg
     8701 cggcgcagct cggcctgctc gacggcggtg cggacggcgg tctcctgcac gacgttgaac
     8761 gccttgccca cctggccgat ctcgtcgtcg ccgaactgca acggcggcgc ctcgcgggcg
     8821 acgtccacct cgtcgccgcg gcccagccgc tccaccacgc tcggcagccg ctcgtgcgcc
     8881 aggttgaagg ccgcctcgcg cagccgttcg agctgccgca ccagcgaccg ggccgtggtg
     8941 atcgagacga ccacggaggc gatgacggcg agcaggccga gaccggcggc gagcaccagc
     9001 cgcacgatga cgccgatcgc taccggcatg gcccgggaca cgatgtcctc gccgccggcc
     9061 aggatcaccc cgcgcaggtc ggccatcgcc tgctcggcgg cggcctgcca cgccgctgcg
     9121 gtcaccggcg ggcgcacgtc ggcgcccttg gccgcgagga cccggtcctg aagggtctgc
     9181 aactgctgga acgcgtcgcc ctcgaccatc cgctcgaagc gtgcgcggtc ggtcggggcg
     9241 agctcccggg cggtgcggtc ggcgaggaac cactgcgcgc cgaccaggcg ggcgaacgcg
     9301 gtctgctcgg ccacggtgat ccggttggcc gcgatcgcac cggtgatcag cgcgtcctgt
     9361 tgggacagca gctcccggga ccggttgagg tcgatgagcg cggcggtgtc cttggcgatc
     9421 tcgtcgtcgt cgaggccgcc gagcgcgtcg aagacggcga agatcgcgtc gaccgcctcg
     9481 tcgtacgcga tgagcgtggc ggtgcggtcg atggtcttgc ggctgacgtc ggcgcgtacc
     9541 tggccgatct ggtccagctc ggtcttcagc tcgccgagcc gctgcatcag ctcctcgctg
     9601 gccgggatct cggtacgcca gtcctgcacc gagcgccaca gcgcggtggc ggtctcgtcg
     9661 gtacgggcgc gctgggcgtc cagctcccgc agccggcccg gatcggactc gcccagatag
     9721 cgcagcgaca gccgccgctc ggcctgcagc tcctgcagca gcgggtcgct cggctcgaag
     9781 acgcgcgcgt tgagcgtctg cacgccgagc aggttgaacc cgtcccgcac ggtcacccac
     9841 gcggcgaacg cccagagcgc ggtcagcgac gccagcagcg cgatgatctt cgtacggaga
     9901 ttcgtactgc gggaacccat cacaccgtcc tggcccggtc tacggtcggt ccgaaatccg
     9961 atcgactccg gcgcacgcta gcagccgtcg tgaactccat tcaagcgatc ctgatcatgg
    10021 tgggtccggc ctcgacggcg cggccggagg ccgccagcac cgccgcgcgc acgatctgcg
    10081 tcgggcggta gagatccttg tcgtgccata gtgccggttc gtcgtcgcat ccgtccagct
    10141 cggacagtcg acggcgtccg cgggcgagcg ccgcggcgat ccgcgcgtcc ccggaacggc
    10201 ctgcgccggc cagtgcgagc accgcgtacg cggtctcctc ggcggtgccg tgccacagtc
    10261 cccaggagcc gtccgggcgc tgcgtgtcca gcagccaggc gacgccccgc tcgacggcgg
    10321 cacgcgccgt gccgtcgggc gcgtggtcgg ccagcgccag cagcaccgcg tacgtggcgt
    10381 agcaggccga ggcgtgccag cggtcctccc agcgcccgtc cggctgctgc cgctccacca
    10441 gccactcggt gacccggcgg cgggcgccgg tgacgccggg tccgctcggc tgctcgccga
    10501 gcgcgtcgag cacgtgcgcg ttagtggtca gcgacgcgcc gtcctccccc ggccaggtgc
    10561 agaagtgccg tccggtgtcg aacccggcca gcggcccgac gccgggggcg cggcccagcc
    10621 gggccagcgc gtagagcgtg acagctgtgg tgtccgcgtc ggcgggcagg ccgggcgcgg
    10681 tggccgcgcc ggacgggccg acggcggcgc gcagctcggt gagcaccggc tcgggcgcgc
    10741 cgaccggcac accggcccgg accaggatgc cgagcaccca ggcgcgctcg aagacggtga
    10801 tcgggctggc gcagggcacc gggccgggcc gggccaccgc gcgcagatag tccagcgccg
    10861 ctccgggctc cggacggccc agccaggcgg cagtggcggc cggggaggcg cccaccgcgc
    10921 cgctggccga gggacgcacg ccggccgccc ggtacgccag ctcaccggcg acctccagcg
    10981 cgtgcgccag cttctccggc acgggccgcc cggcggccag cagcgcgcgt acccgggtca
    11041 ggcgggccgg gtcgagaccg gccggcagcg gcaggcgggg ccggccggcc cactcggcca
    11101 gcccgggtgg cggcccggcc ggtccggtga ggtgccggtc cacggcagtg agcagcgcgg
    11161 gcacgatcag gtcggtggcc ggcaggtcgg gcggcgcgtc gccgcgcagc gcgccggaca
    11221 ggaacgtcag gccccggtgg gccgcggcgg ccggcacggc ggccgggccg tcgcgacgca
    11281 gcacggtcag cagcgcctcg accgcgctca gcgtcggcac cagcgcgtac ccgccgggac
    11341 cgccccagcc gccgtccggc cgctgccggg ccagcagcca ggccaggcgc cggtcgtggc
    11401 cgtccagcca gggcgcgagc gcgaccagcc gggcggtctc gtagaccgac ggcgacgtct
    11461 gcccggccgg ctcgccggtg agcgcggcga ccaggtcgtg cgcggtcccg gaccgggtgg
    11521 cgggcaccga tccggcggtg agcgtcaccg cacgccccag aagtcggtgt tgcggtagaa
    11581 gccggtggtg aagccgagct gccgggacag gaagtcggct tcccggggcg cctcaccggc
    11641 cagcttcgcc agccggacgc ggcagtggtc gacctgctcg gcgaaccgcc gctcgacctc
    11701 ggccgggtcg tccaccagca gcagcgcgtt gaggtcgccg gactcggcgt cgcggcggtg
    11761 ggtgccgagg tcgttcacca gccgcagggc ccgctgcacc tcgtcgctga cggcgaccgc
    11821 gtggtccatc gcctcggcgg tggacaccga tccggtgtgg atccagtgcg ccacgttgac
    11881 cactgtggcg gcgaggttgt cggcgtttgc gaggtagtcg gcgagcgtgg ggcggccggt
    11941 gcgccgccag tcccactcgc gggccatcgc gtcgagcgtg cgttccatcg ccgcacgcca
    12001 gtggccgcgc agcgccgggt agccgggcgc ggcggccacg tcgtcgcgca gctcggccag
    12061 gaaccggccc agtgggtcgt cggtgccggc gccgtcgagc acgtccaggc agacaccggt
    12121 gatccggtcg acctcggccc ggctggtggc ctggtggtcg accagccagt ccacggcgaa
    12181 gccccagagc acggcgcggt tggtcacggc cagctcggcg gcgctgtgcc agggggcgct
    12241 gaacgccatc gcctgggcga tgctgctgaa cagcgtcgcg tcgaacgggt ccgcggggaa
    12301 cagctccggg tgcgcggcgg cggccttgcg caggccgcgc tggccctgcg cggcgagcgc
    12361 gcagacccgg ccctgctccg cggcgacggc gagtaaatcc ggtgtcggcc cgtcggtcat
    12421 gcccgctccg cccgcccggc cgcgacgagt gtcagctcca cccgctcgcg cggccgcagc
    12481 gccgcggcca gccgcaaccc gggtacgccg gggcggtgca gccggaaccg gtagcggctg
    12541 agcatggtgg cgaggatgag ctgcgcctcc aggtagaaca ggtacatgcc gaggcactgg
    12601 tgcggcccac cgccgaacgg gaagtgggcg taccggtgcc gggcccggac ccgctcgggc
    12661 cggaaccgtt ccgggtcgaa ctcgtccggg cggtcccaga actgccgcat ccgctgggtg
    12721 atcagcgggc tgaccgccat cgtcgcgccg ggctcgatcg gcacgccgtc gatgacgtcc
    12781 ccggcgaccg cgcggcgcgg gatgatccat ccgatcgggt agagccgcag cagttcgtcc
    12841 agcaccatcc gggtgtacgt gagccggctc aggtgctcgc ggcgtaccgg ctcgcccccg
    12901 accacctcgt cgatctcggc gtagagccgc tcggccacct cggggtgctg gtccaggtgc
    12961 ggccaggccc aggtcagcac gttgatcgtg gtctcggtgg tggcggcgaa catggccact
    13021 gtgtcgttgc ggacctgccg ctcgtcgagc tgccgcccgt cgtcggtgcg ggcctgccag
    13081 agcgtcgaga tgacgtcgtc gccctggtcg gcggactcgc gggtctcgcg gacgatcggc
    13141 accagcacgt cgtccacgat gcgtacggca cgggcgaacg tgcggtcgcc cggcatcggc
    13201 agcgacagcg gcgcgaacgg cacgatgatg cgggggatga cggcggtggc gatccggtcc
    13261 tgcgcctcga tcacgcgcat cgcgtccggc accgagatgc ggtcggcgaa gagcaccttc
    13321 atgatcgccc ggctgacgat gcgcgcctgc tccacgccga tgtcgaccgg acggccggcg
    13381 cgggccggct cgtccagctc gtcgaccgcg tcgcggatcg cgtcggccat gccgtcgacc
    13441 agcgcctcga cccgtttggc ggtgaacatc ggctggagca tgcgccggct ggccgaccag
    13501 atctgcccct cgccgaggat cccctcgccg aacagccgct tgaccggacg ccagaacagc
    13561 ccatcgcctg ctcgttcgta gttgtccgcc cggtcgcgca ggacgtgctg cacgtgcttg
    13621 gggtgggtga cgaggtaggg gcggaacgag ccgaggttca gccggaccag ttcaccttcg
    13681 gtacggttgc cgatgtcgat gagcgcccgg gcggggtcgc ggagcaccgc cggcaggatc
    13741 tgccgcagcg gcacggttcg gggtcggccg gtgggtcccg gtgtgtccgt tggttcgggc
    13801 acctgaacgc tccctcggtt gactcagggt cgcggcttcg tatcgacccg tgacgttgct
    13861 cgcgagcatg ccatcctgag ccgcagatca aaaggcaggt cggaggatat ttcacgtaac
    13921 aacaatctct ttgtcgagaa tggagcccgt gggatgtgcg tcactcccgt acacagtggt
    13981 ggttgcggag cgcgagcagc gctcacctat cgcggacgcc ggcagaacgc gggcgcggac
    14041 ccgtccgctg tgccaagctt cgggcatgga cgacaagacc atcctgagcc ggatctcgga
    14101 actcgtcgac gaggagcacc ggctgcgggc cgacgcgcag cagcacgagt ccggcaccga
    14161 cgacgaggcc cgggagcggc tgcgggccct ggaggagtcc ctggaccagt gctgggacct
    14221 gctgcgccgt cgccgggccg cgcgccaggc gcacggcgac ccggacgccc agggcgagcg
    14281 cccggtgccg gaggtcgagc gctacctgca atgacccgca cgggtgggcg tcccgggcgg
    14341 ctcgaccacc cgggacgccc gcccgtcagc ggatccccgc ctcccgcagt agcgcctcgg
    14401 tgagcgcctc cggatcggtg acggtggccg gcatcccgcg ggcggcgaac caggcggcca
    14461 ccacccgcac gtcccggccc aggaactcgc cgccctgcgg gttggccacc acgtcgacca
    14521 cctgcggcag gtcgatcatc accagccggc ccgcgtgcac cagcaggttg tacggagaca
    14581 ggtcgccgtg ggcgtacccg gcccgggcca gcacggtgag cgcctcgacc agctgatccc
    14641 acaggtcacg cagctcggcc gcgtcgggcc ggacctgcgc cagccgtggc gcggcctccc
    14701 ccgcctcggc gtcgccgacg aactccagca tcagctcggt gccgagcaac tgcaccggat
    14761 agggcaccgc gatccgcccg gaggcggcgc cgatctccca gagctgggac agcgcggcga
    14821 actcggccgc cgcccactgc ccggcgatca tctgccggcc gaacgcggtc cggccggtca
    14881 tcgcccgcat ctcccgcgac cggcgtaccc ggcggccctc caggtaaccg gcgtcgcggt
    14941 ggaagagccg gtgctgggcg tcgcggtacc gcttgaccgc cagcaggcac gaacggtcgg
    15001 tgtccggcac ggcgcggcgg accaggtgga cgtccgcctc cttgccggtc ttgagcaccc
    15061 ccagctcggt gtcccgggcg gccagttcgg tgaccagcca gtccgggtac ggctcggggc
    15121 cgtggacggc ccggtcccag gaggaccagc tgtcctccgc gtcgggctcg gcgtccgggt
    15181 cggcgagggt cggcgtgggc cgcccccgct tcaggaagtc ggtttcgtcg tcgtcgaagc
    15241 ggctcttgcc gcggccacgg cgctgcggcg ccgggaagtc gtgatcgcgc acgggtggat
    15301 ctgtccttcg atcgaggctg gtggaggcag gtggtacgac cctgcgaaaa cggccatgac
    15361 cgacctcctc tcctcgaccg ggcacccccc ggctgcgcac tcgcgcggca ccatgctcgt
    15421 acgcgccccg gcgcgggtca acggatttcc gcacggtgcc gccgcgctgc ctgccggccc
    15481 gcgccgccgg tcagccggcc agcactgcgg cgacggccgc gatcagcccg tcctcgatcc
    15541 gggtcggcgc gaaccggggg tccgaccagc ggcgtccccg atgcagccag acactgggca
    15601 ggcccaccgc ggtcgcgccg ccgatgtccg cctccgggct gtcgccgacc acccacgcgc
    15661 cgcgcagcgg catccgggcc cgctgggcgg cgagcgcgaa gatcctcggg ttcggcttgc
    15721 tgacgccggc ctcctccgag atcacccagt cggcgacgta gcggtccagg ccggtcttgc
    15781 ggatcttggc gtcctgttga cgggacgcgc cgttggtgac caccaccggc acccagccgg
    15841 cgtcggcggc gatccgcagc gcgcaggcca ccagcggatc gagccgcatg tgcgccacca
    15901 cgccgtcgtg cagctcgtcc accaggtcga tcgaggggat gcgcagcgcg taccggtcgc
    15961 ggatcgcgtc cgcgacgtcc caccggttgg tcagcccgtc ggcgtccacc gacaccagcc
    16021 agtcgaggtc ggcgggcggc gcgccgatgc ccgccaggaa gcgttctccc cagacacgga
    16081 acggcccgtc gcggtccagc agggtgttgt ccagatcgag caggagcaac ggcacttggg
    16141 caccctacgg gaacgctcgg agcaccgaca gggccccggg cccagccacg gtcaggcgac
    16201 gagcgccgta cgggccgcgc cggcgtccac cggccggtcg agcagcatgg tgtgcgccgc
    16261 gcgggtggcc gccagcgctt ccgggtccag cgtcgccacc agcacgtcct ctccggtgtc
    16321 ggcgccccgc gccagcggcc ggccctccgg gtcgtacacc gccgcgccac cgttgaaccg
    16381 ccaggggtcc gcgccgccga cgacgttggc gaacacgacg tacatcgtgt tgtccagcgc
    16441 ccgggcggcg tagtagaggt cgcggcggtg ctccgagccg gccaggtaac cgctcgggca
    16501 gaggtacccg tgcgcgccgt cgccggccgc agcccgggcg tgctccggga agcagccgtc
    16561 gtagcagaca ccaaggccga accgccacgt gtcgacgtcg agtgtcgcgc cccggcggcc
    16621 ggcgtcgaac atctcgcgct cgccgctcca gagctgctgc ttgtcgtacg cggcggtgac
    16681 agtgccggcc gggtcgacga cgagcgagga gatggtgcgc cgccggtcgg ggtggcggac
    16741 ggcggcgccg atcaccactg ccgcgcccgc gtcggcggcg gcggtccgca gcgggtccag
    16801 ccgggggtcg gcgacccggc cgtcggcgtc ggcggccacg tcggtgccct ccgggtcggc
    16861 gcccagcgtc ggcgggtggt acgccggcag gaacagctcg ggcagcacca cgacccgggc
    16921 gccctcggcc cgggcgacga ggcgggcggc ggcgcgggcg ttgccggcga cgtcaccggg
    16981 gacgggctgg gcctggacgg cggcgacggt gagcgggcgc gcgggaaggg cggtcacacg
    17041 ccgatcctaa ccatcggacg cggccggatg atcttccgaa ttcgcatctc aagccgtacg
    17101 tacggtttgc atcacgcggt tccacctgcg acgatccgtt cgtgcccaga gtaagtcagg
    17161 accagctcga cgcgcgccgg caggagatcc tcgcggcggc gcgggcgtgt ttcgcccggc
    17221 acggctacga gggcgccaca gtgcgtcggc tggaggaggc caccggcctg tcccggggcg
    17281 cgatcttcca ccacttccgg gacaaggact ccctgttcct cgccgtcgcc gaggacgacg
    17341 ccgccgccat ggtggagacg gtcgcccgca acggcctggt gcaggtcatg cgcgacctgc
    17401 tggcccgggc ggtctcgccc gacacgaccg gctggctcgg cagccagctg gaggtctcgc
    17461 gccggctgcg taccgacccg gccttcgcca agcgctgggc ggagcgttcc gaagccatcg
    17521 ccgcggcgac ccgggagcgc ctggtacgcc agcgcgaggc cggcgtgctg cgcgacgacg
    17581 tcccgatcga cgtgctggcc cagttcctgg agctggccta cgacggcttg gtgctgcacc
    17641 tggcgatggg ccgcccggcc ggcgacctgg cccgggtgct cgacctggtc gaggaggcag
    17701 tgcgccggca ctgagcccgc cggtctcggt ccggtaactg cgccgctcca ggagatcgac
    17761 tctggcgcgc ctgctccaca atgagccgcg acccctcctc gcgacaggag cagacgatga
    17821 ccccctccga cacctggggc atccccggcc ccgtattcct gcgctggtac ctcctgctcg
    17881 ccgtcgtcct ggtcatcggc gcgatcgtgt accggcgtcg gatgctggcc ggcaccccgg
    17941 tgaccgatca cggcacgttg ggtccgcagc aggtcgccta cctcaacggc ggcgaccagc
    18001 tcgccgtctg ggccacgctc ggcgcgctgc gccacgcggg cgcggtcggc gtacgacccg
    18061 accggcggct caccaccggc ggtccgctgc cggccggggc caccccgctg gaccaggcgg
    18121 tccaccacgc ggcgagccgc ggcctgcgga cccgggacct ggccgccgac gagtgggtgc
    18181 ggcgcgcgct cgacgagctg cgcgacggcc tggtacgccg gggcctggcc ctggaccagg
    18241 agcggcgccg gacgctgcgg cgcggcgcgc tgctgatcgg cttcctgctg gcaattggcg
    18301 tcgtgcgtgc gatctccggc ctgctcaacg accggcccac cggctggctg ctgctcagcc
    18361 tgttcccgct cggcctcgcg ttcctgctgc tcaaccgcgt gccctggcgt acccgggcgg
    18421 ccaccgccgc gctgaacgac atgcgccgcc ggcacgcctg gctgcgaccg gccgcctccc
    18481 ccgcgtacgc cacgtacggc gcgacggatg tggcgctggg cgtggcgctg ttcggcaccg
    18541 ccacgctctg gaccatggat ccgggcttcg ccgagcaggc cgagatccag cggcaggcga
    18601 tgggcaacgt cggcggcgcg agctccggca cctcctgtgg aggcggcgcc tccacgtgcg
    18661 gcggtggcag ctcctgcggc ggaggcggtg gctgcggcgg aggcgggtgc ggcggatgag
    18721 cggcccgtcc ggcgtcggca tcggctggcg tcccgagatc gccggtttcg tggccgggct
    18781 gccggggctg cgtttcgtcg aggtggtcgc ggaggcggtc gcaccggccg ggccgctccc
    18841 ggacgggctc gccgagctgc gcggacgcgg cgtcgatgtc gtaccccacg gggtgcggct
    18901 gtccctcggc ggcgcggaac cggtcgatcc ggcccgggtg gcgcacctgg ccgcggtggc
    18961 cgcggccctg gacgcgccgc tggtgagtga gcacatcgcg ttcgtgcggg ccggcggtct
    19021 ggaggccggt cacctgctgc cgctgccgcg cagccgcgag gcggtcgccg cggtggtggc
    19081 gaacgtgcgg cggacgcagg cggagctgcc ggtgccgctg gccctggagc cgatcgccgc
    19141 gctcttcgac tggcccgacg acgagctgga cgaggcggac ttcctcaccg agatcctcga
    19201 cgccaccggc gcgctgctgc tgctcgacgt cgcgaacgtg cacgccaacg cccgcaaccg
    19261 gggcggcgag ccgaccgcgc tgctggaccg gctgccgctg gaacgcatcg cctacgcgca
    19321 cgtcgcgggc ggcgccgaac acggcggctt ctaccacgac acgcacaccg acccggtgcc
    19381 cgccgccgtg ctggacctgg tccgcgagtt gtgccggcgg cgccggccgc ccgcgttgct
    19441 gctggaacgc gacgggcact acccgcccgc cgccgagctg cgcgcggagc tggacgcgct
    19501 cgccgccgcc tccggccacc cggcggtcac gtgagcggcg acctggcggc ccggcaggcc
    19561 gagctggtcg ccgcgctcgt cgccggtgga ccgctgccgc ccggcttcgc accggccccg
    19621 gtcgaggcgg cccgccgggc gctgctgcgc aagcgggccg cggacgtggc ccggcactgg
    19681 ccgctgctcg ccgccggcct cggcgcgcac tggccggcga cgttcaccgc gtgggcggac
    19741 ggacgcccct cgaacggctc cctgcgcgac ggctgggacc tggcccgcga gctgcgcgac
    19801 cggggcacgc tgccgccgct gggcgcggag gagctggccg cgcgcgaggt tgcgagccgc
    19861 tacgacggcc accgcccgcc ccggccccgc cggatgccgg ccgtcgcccg ggccggcggc
    19921 gccgtcgcgg cccagttcgc cggccgggta cgcctgctgc ggcccgcccc gcgctgacac
    19981 gcgcccccgg gtacggcagg atcgggcgta tggatctcgg actcgccgac cgggtgtacg
    20041 tgctgaccgg cgcctccggc ggcctcggct tcgccaccgc cgaacaactc gtcgccgacg
    20101 gcgcccgggt ggtcatctcc gcgcgtaccc cggaacgggt ggccgccgcg atcgaggcgc
    20161 tcggcgaccc gcagcgggcg atcgggctga ccgccgacct cgccgattcc gccaccccgg
    20221 agcggctcgt cgccgccgcc cgcgaacact tcggccgcct cgacggcgcg ctgatctcgg
    20281 tcggcggccc gccgcccggc accgccgcca ccgtcaccga cgagcagtgg cgcgagtcgt
    20341 tcgagacggt cttcctgggc agcgtccggc tcgcccgcac ggtggccggc gcgctcaccg
    20401 acggcggcgc gatcgggctg gtgctgtcca cctcggtacg cggaccgctg gccggcctcg
    20461 gcatctccaa cgggctgcga ccgggcctgg ccggcgtggc caaggacatg gccgacgagt
    20521 tcggcccgcg cggcgtccgc gtggtcagcc tgctacccgg gcggatcatg accgaccgca
    20581 accgggagct gctggccggc tccggcgatc ccgagcgcgc ccgcgcccag gcggaggcgg
    20641 cgatcccgct cgggcgaatc ggcgacccgg cggagttcgg ccgggtggcg gcgttcctgc
    20701 tctcccccgc cgccgggtac gtcaccgggg tgaccgtccc ggtcgacggc ggcgcgctgc
    20761 gcgggctgtg acagtggccg ctgtggtggg ccgggcgccc ggggcggtgg gccggtgagc
    20821 gaccgacggc gcccgggcgg tgggcggccc gaggcggccc cggggccggg cacgcccgcc
    20881 cggcggcacc cacgccccag ccgcgagcag ctcgcggcgg cggccgaccg gctgctgccg
    20941 gacgtcatcg cgcccggcct ggacgtgctc ttcgtcggca tcaacccggg tctgtggtcg
    21001 gcggcgaccg gctggcactt cgcccgtccg ggcaaccggt tctggcccgc cctgcaccgg
    21061 ggcgggttca ccccgcgtct gctgcacccc agcgagcagg acgcgctgcc cgcactcggc
    21121 ctcgggatca ccaacatggt ggcccgcgcc agtgcccgcg ccgacgagct gaccgccgcc
    21181 gaactggtcg acggcgcggc gacgctcacc gcgaaggtcg agcggtaccg gccgcgctgg
    21241 gtggcggtgg tcggcgtgac cgcgtaccgg atcgggttca cccggccgaa ggccggcttc
    21301 gggccgcagc ccgagacgct cgggccggcc cggctgtggg tgctgcccaa cccgagcggc
    21361 ctgaacgccc acttcacccc ggagacgctc ggcgccgcgt tcgccgagct gcgtgccgcg
    21421 gtcgccgcgg gttagggccc cggtcgccgc gagctagggc tgcggccgtc cgggtcgcca
    21481 cggcccggcc gccgggtgcc cgtccacccg gtcggtgccg atccacgccc gccggcgccg
    21541 ggattgaggc ctcgcgggcc gctagttggc tgccgccggg ggcatggcct cgtgggcgac
    21601 gtaggtgccc atcggcacag tggtcaccac cggctccggc tgctccgcct cggcgtgcgg
    21661 cgcgggcgag tcggtgaccg cgaactgggt gcggtacagc tcggcgtaca ggccgccgac
    21721 ggccaccagt tcgtcgtgcc ggccgcgctc cacgatccgc ccctcgtcga gcacgaggat
    21781 ctggtccgcg tcgcgcaccg tcgagagccg gtgcgcgatc accagcgcgg tacggccggt
    21841 cagcgccacc gacagcgccc gctgcaccgc tgcctcgctc tccgagtcca ggtgggcggt
    21901 ggcctcgtcc aggatcacta tcgacggggc cttgagcagc aaccgggcga tggcgatgcg
    21961 ctgcttctcg ccgccggaga aacggtagcc gcgctcgccg accgtcgtgt cgagcccgtc
    22021 cggcagcgcc cggaccaggt cggccacctg cgcgccggcc agggcggccc agatctcgtc
    22081 gtcggtggcg tcgggcttgg cgtaccgcag gttctcgcgg atggtctcgt ggaacaggtg
    22141 cgagtcctgg gtgaccacgc cgatctcgtc gcgcagcgag gcgagcgtcg cgtcccgcac
    22201 gtcgacgccg ccgacgagca cctggccctc gctgacgtcg tagatccggg agatcagcat
    22261 ggacagcgtc gacttgccgg cgccggaggg gccgaccagg gccaccatct gcccgggctc
    22321 gacggcgaac gagacgccct tgagcaccgg ctcgttcacc gtacggtcga gggtcgagac
    22381 ctcttccagc gacgcgagcg acacctcggc ggcgctcggg tagcggaagc gcacgtcgcg
    22441 gaactcgacc cggccgctgc cgcgcggcac cggcaccgcg tcgggcttct ccgcgatgcc
    22501 cggacgcagg tcgagcacct cgaagacgcg gtcgaacgag acgagcgcgc tcatcacgtc
    22561 gacccggacg ttggagagcg cggtgagcgg gccgtagagg cgggtcagca gcagcgccag
    22621 cttgacgacg gtgccggcgc tgaccgcacc ggtgaccgcc agccagccgc ccaccccgta
    22681 ggtgagcgcc tgggccagcg acgcgacgag cagcatcgcc acgaagaacg tccgcgagta
    22741 catcgcggac tggatgccga tgtcgcgcac ccgctcggcc cggcgggcga accggtcggc
    22801 ctcgacctcc ggcgcgccga acagcttgac cagcagcgct ccggccacgc cgaaccgctc
    22861 ggtcatggtc gcgttcatct tcgcgtcgag gttgtacgac tcgcgggtga tctcggccag
    22921 gcgccggccc acccggcggg ccgggatgat gaagatcggc agcagcacca gcgccagcac
    22981 ggtgatctgc caggacagca cgagcatcgc gccggcggtg agcacgagct ggatgacgtt
    23041 gctgaccacc ccggacagcg tcgaggtgaa cgcccgctgc gcgccgagca cgtcgttgtt
    23101 gagccggctc acgagcgcgc cggtctgcgt gcgggtgaag aactgcagcg gcatccgctg
    23161 gacgtggtcg tagacccggg tgcgcaggtc gaggattatg ccctcgccga tgcgggccga
    23221 ataccaccgc tggaccaggg agaacagggc atcggccacg gcgagcgcgg cgatgatcag
    23281 ggcgagccgg accacagtcg tgcgggcgtc cggaccgccg ccggcgatcg cgtcgatgac
    23341 gtcgccggcg agcagcggcg tggccacgcc gatcaccgcg gcgatgatca cggtgatcag
    23401 gaagacgacg atgtcacgcc ggtagggccg ggcgaacgcg acgatccgcc gggccgtgcc
    23461 gcgcttgagc tcgtgggcgg agacctcgtc ccggttgcgc agcgaccgga gcatgctcca
    23521 gccgcccatg ccgccgccgg ccatcgggtg ggacactcgt cacctccagg tcgtcaggca
    23581 gcatgaatcg tcggagtcca ttctccagac gcctgtgaca acctcgcgag taacccagat
    23641 cttcccgaac ggtccttacg aaatcgcgct ccgggccggt tactcgcccc ggccggccag
    23701 gtcccggata cgccgggtct gcgcctcccg ctcggcgcgc tgctgctcgg cgtgcgtacg
    23761 gtcggccgcg cccgccagga gcgccttgat ctcgacgatc gcgtcccggt tgttggcgag
    23821 gagcccggcc gacaggtcac gcaccgcggc gtccagctcg tcgttcggca ccacgagcgt
    23881 ggccaggccg atccggtccg cctcggtggc gtccatccgg cggccggtgg cgcagatctc
    23941 cagggcgcgc gaatagccga ccagctcgac caggcggcgc gtgccggcca gatcgggcac
    24001 caggccgagt gtcacctcgg ccatcgagag cctggcgtcg gcggcgagca cacgcatgtc
    24061 gcaggcgagc gcgagctgga agccggcgcc gatggcgtgg ccctgcaccg cggcgatcga
    24121 caccacgtcc ggccggtgca gccaggtgaa gccgccctgg tactcggcga tccggtcggc
    24181 gcactccgcc tccgggagcg cggccaactc ggcgaaggag cccggcccgg tggcaccggc
    24241 gaccgccagg tccaggcccg cggagaaggc gcgcccctcg ccgcgtacga cgacgacgcg
    24301 gacgtcgccg ggcaggtcgc gggagaagtc gctcatcgcc cgccacatcg ccggggtctg
    24361 ggcgttgagc acgtcgggcc ggcacaacgt caccgtcgca accggcccgt cgcagtcgaa
    24421 gcgcactccg gtcgtctcgg cggtcaccgg acgccccgga acactgcgct gatggacgac
    24481 gctgggcggc gggtcacgcc ttcttccggc gccgggcgcc gccgcgctgc cgca
//
