LOCUS       NZ_CP118233            21098 bp    DNA     circular CON 13-JUL-2024
DEFINITION  Micromonospora chalcea strain 1K05785M01 chromosome, complete
            genome.
ACCESSION   NZ_CP118233
VERSION     NZ_CP118233.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora chalcea
  ORGANISM  Micromonospora chalcea
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Study on the Growth Characteristics and Drug Resistance Related
            Proteins of Micromonospora chalcea MCCC 1K05785
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2023) Tianjin University, Tianjin University,
            Weijinlu Nub92, Tianjin, Tianjin 300072, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2022
            Assembly Method                   :: CLC NGS Cell v. 5.29
            Assembly Name                     :: TJU-micro-1.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028768405.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 23:01:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,224
            CDSs (total)                      :: 6,161
            Genes (coding)                    :: 6,110
            CDSs (with protein)               :: 6,110
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 51
            CDSs (without protein)            :: 51
            Pseudo Genes (ambiguous residues) :: 0 of 51
            Pseudo Genes (frameshifted)       :: 16 of 51
            Pseudo Genes (incomplete)         :: 40 of 51
            Pseudo Genes (internal stop)      :: 2 of 51
            Pseudo Genes (multiple problems)  :: 7 of 51
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:37:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2660043
            Orig. end                         :: 2681141
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP118233.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21098
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="15"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21098
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21098
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11098](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11098)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    complement(231..246)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.21"
                     /tool="antismash"
     gene            complement(486..1937)
                     /db_xref="GeneID:91356722"
                     /gene="argG"
                     /locus_tag="PVK74_RS11185"
                     /old_locus_tag="PVK74_11185"
     CDS             complement(486..1937)
                     /EC_number="6.3.4.5"
                     /GO_function="GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356722"
                     /gene="argG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1291: argininosuccinate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020661635.1"
                     /locus_tag="PVK74_RS11185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11185"
                     /product="argininosuccinate synthase"
                     /protein_id="WP_064445361.1"
                     /transl_table=11
                     /translation="MSKVLTSLPIGERVGIAFSGGLDTSVAVAWMRDKGAIPCAYTADI
                     GQYDEPDIASVPGRAHTYGAEVARLVDCRAALVEEGLAALTCGAFHIRSGGRAYFNTTP
                     LGRAVTGTLLVRAMIADDVQIWGDGSTFKGNDIERFYRYGLLANPQLRIYKPWLDTDFV
                     TELGGRTEMSEWLLERGLPYRDSTEKAYSTDANIWGATHEAKTLEHLDTGIETVEPIMG
                     VKFWDPSVEIPTEDVTIGFDQGRPVTINGKEFGSAVDLVLEANAIGGRHGLGMSDQIEN
                     RIIEAKSRGIYEAPGMALLHAAYERLVNAIHNEDTLANYHNEGRRLGRLMYEGRWLDPQ
                     ALMLRESLQRWVGTAVTGEVTLRLRRGEDYSILDTTGPAFSYHPDKLSMERTQDSAFGP
                     ADRIGQLTMRNLDIADSRAKLEQYASVGMVGGGNPQRVVGAAQAASTGLIGAMPQGGAE
                     AIASRGVPTAEDEALDRAAMEFGVD"
     misc_feature    1959..1972
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: strong, score: 19.46"
                     /tool="antismash"
     gene            complement(1982..2830)
                     /db_xref="GeneID:91356723"
                     /locus_tag="PVK74_RS11190"
                     /old_locus_tag="PVK74_11190"
     CDS             complement(1982..2830)
                     /GO_function="GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019031474.1"
                     /locus_tag="PVK74_RS11190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11190"
                     /product="RNA methyltransferase"
                     /protein_id="WP_274479037.1"
                     /transl_table=11
                     /translation="MPGRPRRAGQNRVVPVHEITDPDDDRIADYRALTDVELRTRWEPP
                     HGLFIAEGELVLRRALRAGYPARSYLVDAKRVDQLADLDTGDAPVYAATPDVLQRATGF
                     HVHRGVLASFHRKPLRSADEVLAAARRVVILEDVNNHTNLGAIFRGAAALGVDAVLLSP
                     TCADPLYRRSVRVSMGEVFAVPYAKLDSWPGGLDQVRAAGFTVLAMTPAPDAVPVQRLT
                     PAQRERAALLLGAEGPGLTAAAQAASDVRVVIPMRRGVDSLNVAAAAAVAFWELGRDDP
                     L"
     gene            2897..4729
                     /db_xref="GeneID:91356724"
                     /locus_tag="PVK74_RS11195"
                     /old_locus_tag="PVK74_11195"
     CDS             2897..4729
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356724"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287358.1"
                     /locus_tag="PVK74_RS11195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11195"
                     /product="thiamine pyrophosphate-requiring protein"
                     /protein_id="WP_274479038.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3.6e-37, bitscore:
                     126.1, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.8e-25, bitscore:
                     86.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGADHDGNLPRDATVADYLVARLAEWGVHRYYGYPGDGINGMTSA
                     LQRAEGRARFIQVRHEETAGFAAGAHVKYGGGPLGCVVVTSGPGAIHALNGLYDAKLDH
                     QPVVALLGHTALPAEGGGYYQEVDLLSLYKDVASAFLAQLDDPSQARHLVDRACRTALA
                     RRTVTALVLPSDVQDLPAVPHPPHAHGYYHTSAVPSSEPTVPPEADVRRAAEVLRGGER
                     VAMLVGQGALGAEDEVRRIADRLGAGVATALLGFTAVDHRQPWVTGAIGLLGSRPSWQL
                     MRECDRLLIVGSQMPYSEFYPPEGQARAVQIDIDGSRMGLRYPTEVNLTGDAGPTLRAL
                     LRELDPGPGPTAWRATIADATGKWRAAQREVAAQPADPVNPQSLFTSLDDALPDDAVLA
                     VDCGTATAWYARHVRVRPGMLASLSGTLLSMGGGMPYALAAKFAHPDRPVIALLGDGAM
                     QMNGVNELITVAKYWREWADPRFVVLVLNNRDLAFVSWEQRSSEGTPMFPDSQDLPDVA
                     YHKWAEVLGLGGELVDSPDRVDGLWQRVLDADRPVVVNAVVDPAELMLPPHFTAEQARK
                     TAAAVLRGDSDRAGIVRRGVPAALATYRPRRRGR"
     gene            complement(4734..5294)
                     /db_xref="GeneID:91356725"
                     /locus_tag="PVK74_RS11200"
                     /old_locus_tag="PVK74_11200"
     CDS             complement(4734..5294)
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475949.1"
                     /locus_tag="PVK74_RS11200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11200"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_274479039.1"
                     /transl_table=11
                     /translation="MGNVIYGVHTSVDGFIEGPNGEFDWPEMGEELSAYSIDLAERASA
                     FVYGRRVWEMMASYWPQVESISDHPHDLAFAPIWRRTPKIVVSRTLAKAPHGAVVVGGG
                     DLAKEFAEVRERFPGDLLVTGGTGAATALAALGLVDTYEVIVHPVVLGGGRQVLPDLAR
                     QHLRLVETRQFDGRSVLLRYARA"
     gene            complement(5401..8520)
                     /db_xref="GeneID:91356726"
                     /locus_tag="PVK74_RS11205"
                     /old_locus_tag="PVK74_11205"
     CDS             complement(5401..8520)
                     /codon_start=1
                     /db_xref="GeneID:91356726"
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.4"
                     /locus_tag="PVK74_RS11205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11205"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_274479040.1"
                     /transl_table=11
                     /translation="MFRLLGPVEVCLDDRTVRVGGPRSQAMLAALLLEANRIVPVSRLM
                     DAAWGGHPPASADVQVRNRVAAARRALRAAGLPGDVIGTHGSGYLLTVAEGQLDLDVFE
                     ERVRRAEGLLDRGGAPEEVVSGLREALAMWRGPALDGLRTPALTAAAQRLDERRMTVVE
                     RCLGLELGLGRYDSVIGRLTELVEVYPWRESLVGQLMRALYLADRQGEALDRFDQLRRR
                     LAEELGIDPTAQLIRLRDLILRNDPSLRPALDAGSVVAPPDRPPGSGPGQAAAAAQHGI
                     AAQHGGAAQHGAAGPDGAARPPVRMLPAGLTDFVGREEQIAAVLEWLPERPAVAVTAIS
                     GLPGVGKTTLAVRIAHQLGPAYPGPHLYVDLNGHDHPAPPVEVLGRFLRALGVPGAQIP
                     ADLEERAALFRGAMAERPGVVLLDNAADAAQVRPLLPGTDTVVLVTSRRALVDVDGAHQ
                     LRLEPLPEADALRLLAGIIGPDRVAAEPGSASDVVHHCGLLPLAVRIAGARLAIPGVLS
                     LRQAAAQLAELSHRLDHLARADRSIRAAFHSAYVALDEPARRLLRRFAVLDLDRAPPWL
                     PAVLLDDEAGAANAVTGLVEANLVEVTGPDELGQVRYHLHDLVRAFARERAAREEGPRE
                     RPEVLRRVFGTWLTLTEQARVALSQEGGAVIVADLPRSPAPTGEHLRDPKRWFGAERAA
                     LLAGIEQAAATPGLEDYSWALAWHCDYYLFVDARVDDLTRVTEIGLAAAERRRHPEGIA
                     RLRLCVAFAALLRSDLEAALGYARAAAAAAEPLDQPWLRADIAGVENQVYEGLGDRPAA
                     RASLVRSIELYQEAGDEVAAGPKLARLGVLQFQEGDPAAGETLARAVALLRAAGTPRPL
                     AFGLRASGRWHDHRGAVDEARAAYLEALELVRRHGDRLGEVALLSEVAAMLAGHGRLGE
                     AAGYADTALEQAREMRVAAYLAYARYAQGRISLMSGDPARARVLLEQAADDLTASPPLQ
                     LEALMDLARAVERLTGAEAARDVWRRAHEVAARIGATATADEIERRLAGP"
     gene            complement(8683..9990)
                     /db_xref="GeneID:91356727"
                     /locus_tag="PVK74_RS11210"
                     /old_locus_tag="PVK74_11210"
     CDS             complement(8683..9990)
                     /codon_start=1
                     /db_xref="GeneID:91356727"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PVK74_RS11210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PVK74_11210"
                     /product="hypothetical protein"
                     /protein_id="WP_274479041.1"
                     /transl_table=11
                     /translation="MTTTGVEAAPDLGAATRVRFHPLRIRPSDDDPDSVVVGRPEVGEF
                     VELPAIGVRAVELLDGGAPIGVAEERIAADHDVDLDLVDLVLALREAGLVAEVDGRPTG
                     GARREDRPHLPWLRARHVRWLFGPAAKVAYVALVAATLATVVRRPELLPSYRDFFWTGY
                     VGLAVLVNTVLFSGTAVLHEFSHLVAARSLDAPARIRFATRLHHLVLETDVTAIWSVPR
                     RHRYRVYLSGLLWDSAVVCAALLVMAYARPHPLVGGLLSAVVLVIVMSMALQLHVYMRT
                     DCYFVLLDLLRCRNLFQDGFAYARHLLRRGLHAALPGRVTPSAGDPTAVLPPHERRAVR
                     IYALAVVAGSAVALSSFVLFGIPIVAHGAIQAGSAVLAGATGGSLLAAVDGALVLLVEG
                     TLQAMFLVTFYRRHSRRRQARGTSGQAPHAAPDPIG"
     gene            complement(10001..11098)
                     /db_xref="GeneID:91356728"
                     /locus_tag="PVK74_RS11215"
                     /old_locus_tag="PVK74_11215"
     CDS             complement(10001..11098)
                     /codon_start=1
                     /db_xref="GeneID:91356728"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013094.4"
                     /locus_tag="PVK74_RS11215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11215"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_113972452.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 1.2e-28,
                     bitscore: 97.6, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 1.8e-37, bitscore: 127.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKPRVKSVHEPYTLPGNRLIIGLMQYGVASEIQDDEDGTIARIL
                     TLLDGTRYVWEVCADLAETHPGIDEDSVREVVEQLIAQGFVEDAAAPLPDGFTAEAAQR
                     YDRARHFYAWIDTQPRSSPFEVQARIGRARVSVLGLGGTGTAVAAGLVASGVGGLHCAD
                     FDVIDQPNLTRQLLYTESDLGQPKVKVAVDRLRAMNSHVDVTGEECRVRSADDLVPLMN
                     GRDAFVLCADRPVDQIQDWTNEAALRTGTPWFMALYTGPMTVVGSFLPGRTGCYTCLRR
                     RPDKHEIQTDGTPLRGGERPNAVIAATANVTGHLCALEVLYHLGGLPQQVAGRVFHQNA
                     ARWDHHYFIDVPRDPDCPSCGPRGA"
     aSDomain        complement(10811..11098)
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_PVK74_RS11215_Pantocin_Microcin_RRE.1
                     "
                     /evalue="5.60E-31"
                     /identifier="RREFam017.1"
                     /label="PVK74_RS11215"
                     /locus_tag="PVK74_RS11215"
                     /protein_end="96"
                     /protein_start="0"
                     /score="97.6"
                     /tool="antismash"
                     /translation="MLKPRVKSVHEPYTLPGNRLIIGLMQYGVASEIQDDEDGTIARIL
                     TLLDGTRYVWEVCADLAETHPGIDEDSVREVVEQLIAQGFVEDAAAPLPDG"
     misc_feature    11366..11381
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.79"
                     /tool="antismash"
     gene            11430..11789
                     /db_xref="GeneID:91356729"
                     /locus_tag="PVK74_RS11220"
                     /old_locus_tag="PVK74_11220"
     CDS             11430..11789
                     /codon_start=1
                     /db_xref="GeneID:91356729"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PVK74_RS11220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PVK74_11220"
                     /product="hypothetical protein"
                     /protein_id="WP_274479042.1"
                     /transl_table=11
                     /translation="MARPVMIALLGVDGSGRTNQAEALAEWLRRRGVRARYFENAGGRP
                     LWNRLARALGRADGLALFGRTVHPALEATVRAAAVARLTGRVAVLDRWTWCQDVIMAAR
                     GDPGGGWPRAGGGVK"
     misc_feature    complement(11454..11467)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     gene            complement(11807..12715)
                     /db_xref="GeneID:91356730"
                     /locus_tag="PVK74_RS11225"
                     /old_locus_tag="PVK74_11225"
     CDS             complement(11807..12715)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356730"
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF033580.1"
                     /locus_tag="PVK74_RS11225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11225"
                     /product="IS5 family transposase"
                     /protein_id="WP_274476701.1"
                     /transl_table=11
                     /translation="MTLYPITVTPSASPRRYPSQRVRRERERAVRRRYPSDLTDAQWAL
                     IAPLVTPASVGRRGRPPSHPMRAIVTAILYVACTGCPWRALPREFPPPGTVYWWFARWR
                     DDHTLMRLHDRLREQCRTAAGRHAHPSAGAIDSQSVRAADTVPRHSRGFDVAKKVNGRK
                     RHIVVDTMGLLLAVMITGAHVNDRTIARDLLWRTRLFHPRLRLLWADGGYIGTLSTWAR
                     HALDLTVHLVHKLPGQHTFVVLPRRWVVERTFAWISKKRRCVRDYEHLPTSHAAFVTWA
                     MIHVMVTRLARHTKPAQATHT"
     gene            complement(12873..15074)
                     /db_xref="GeneID:91356731"
                     /locus_tag="PVK74_RS11230"
                     /old_locus_tag="PVK74_11230"
     CDS             complement(12873..15074)
                     /codon_start=1
                     /db_xref="GeneID:91356731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018827420.1"
                     /locus_tag="PVK74_RS11230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11230"
                     /product="transglycosylase domain-containing protein"
                     /protein_id="WP_274479043.1"
                     /transl_table=11
                     /translation="MPSPRSPLSRLFTVLLAGLLAGLVLAVAALPAGLLGGFAARAALG
                     AYADLPDALRTPSQPQRSYLYANDGKTLITTFYDVNRTDVSLDEIAPVMRQAIIAAEDR
                     RFYSHGGADLRGIARALVANVKGGGTEQGGSTLTMQYVRNVLKTDPNRTPAERQAATEQ
                     TVGRKLQEIRYANALEQSLSKDEILNRYLNIAYFGSGAYGVAAASQRYFGKAPADLTLG
                     EAALLAGLVQSPEAYSPIDGDLDQALARRAYVLDAMAETGAITAQQAAAAKAQAPTLRP
                     TAQPNGCTATAQGHDDWGFFCDYLRRWWLTQPAFGATPEEREQALRRGGYRVVTTLDAK
                     IQETAQEQATKVYGYGNKRALPIAAVEPGTGRVLAMAVNRHYSLDANPDGQANHPNTVN
                     PLISGGASVDGYQAGSTFKMFTMLAALEAGKPLSTGFDAPSRLPTRYASDDEGNCDGTW
                     CPANANPQWMDGYRMMWDGFGRSVNTYFVWLAEQVGEDKVVEMAQRLGITFRADSDATF
                     ARDHAADWGAFTLGVAATTPLDLANAYATVAAEGTYCTPLPVVSVTTPDGGTVDVGQPE
                     CKRVLDPDVARAATDAARCPVGQQSAFGQCNGGTATAVDSIVGRPVAGKTGSSERNATE
                     TFVGYTPQVAVAGIAANPDDVTDLVGSAVQAKVIDAVARTIRTAVTGKPVADFTAPSRA
                     LVGDPQRPQPPRRTEPDRREQREDRELPSDVLRWLRDRG"
     misc_feature    15123..15137
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.97"
                     /tool="antismash"
     misc_feature    15126..15141
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.49"
                     /tool="antismash"
     gene            complement(15166..15969)
                     /db_xref="GeneID:91356732"
                     /locus_tag="PVK74_RS11235"
                     /old_locus_tag="PVK74_11235"
     CDS             complement(15166..15969)
                     /codon_start=1
                     /db_xref="GeneID:91356732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788357.1"
                     /locus_tag="PVK74_RS11235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11235"
                     /product="hypothetical protein"
                     /protein_id="WP_043329731.1"
                     /transl_table=11
                     /translation="MKDPANRLFSRTPVPGAHDPAGPIGSRRTGGGFGVLPFVSEPGPG
                     APATDATWAWSIRRFARAAVWLLPAYAVLYGLVAMASDGGVGNDPYPADGRPLYLVGWV
                     ASVWLGLLALLALTGLLAATRCRRVALAGLLASIGGMVLMLPFAGLAEQTPVFGVTARG
                     IVLFGATLYSVGWFLTGWSVARSGMFSYGDGTMLMIAAPLLGLGGALIGSLQTFGAIFV
                     LVAGIGIGYRSGRLVPETIARDAAAASVAAAPVPPASPKGPLGAG"
     gene            complement(16099..17205)
                     /db_xref="GeneID:91356733"
                     /locus_tag="PVK74_RS11240"
                     /old_locus_tag="PVK74_11240"
     CDS             complement(16099..17205)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183342.1"
                     /locus_tag="PVK74_RS11240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11240"
                     /product="SPFH domain-containing protein"
                     /protein_id="WP_043329729.1"
                     /transl_table=11
                     /translation="MEFLAILMIAVALIGVVTLFKAVRIVPQQRQDVVERLGRYKRTLN
                     PGLNLLVPFVDAVRTKVDMREQVVSFPPQPVITSDNLVVSIDTVLYFKVVDSVRATYEI
                     SNFLQAIEQLTVTTLRNVIGSLDLERALTSREEINRHLSGVLDETTGRWGIKVTRVEIK
                     AIEPPPSIRDSMEKQMRAERDRRAAILNAEGHKQSQILTAEGEKQAAVLRADGDRQARI
                     LQAEGQAKAIRTVFDAIHTANPSQKVLAYQYLQALPQIANGTANKVWIVPTELTKALEG
                     MGGALGGLANMAGDVPSPEAARSAGEVEREAAEAAQAAAVAAQEIHNEVRVAEAQATGG
                     NAPQGLPAPEPVSPASLVNDPADQRERG"
     gene            complement(17211..17684)
                     /db_xref="GeneID:91356734"
                     /locus_tag="PVK74_RS11245"
                     /old_locus_tag="PVK74_11245"
     CDS             complement(17211..17684)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018740695.1"
                     /locus_tag="PVK74_RS11245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11245"
                     /product="NfeD family protein"
                     /protein_id="WP_030504273.1"
                     /transl_table=11
                     /translation="MDAVFWIVLGVVLAVAEIFTTTLFLIMFGVGAFAAAGAAALGAPV
                     ALQAVIFAVVSALSVAVVRPVVRRHARPAIETGEQPFGVEALEGATAVVLEPVDSERGM
                     IKIDGELWTARSYDATRSYAEGERVQVIKVRGATALVWQDDISTPGELPEAKR"
     gene            17783..19093
                     /db_xref="GeneID:91356735"
                     /locus_tag="PVK74_RS11250"
                     /old_locus_tag="PVK74_11250"
     CDS             17783..19093
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91356735"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475945.1"
                     /locus_tag="PVK74_RS11250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11250"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_274479044.1"
                     /transl_table=11
                     /translation="MPLLPETARQVDLLVARAQAEGRGPSLALGVVRDGRLAHLAVAGE
                     TPRPDADLQYRIGSITKTMTAVLVMQQRDAGRLSLDDPLDAHLPGTPVGSVTVRQLLGH
                     VSGLQREPDGDWWERVGGTDLDTLLAGLTSDKIAYPPHFVYHYSNLAYGLLGAALERIT
                     GTPWAELLTERLLAPLGMRRTTYHPTEPYARGYVVHPWHETLREEPRTDTAAMAPAGQL
                     WSTVEDLGRWATFLADPDPALLSPATLTEMCAPMVINDLDSWTGGHGLGIELYRVGDRV
                     YVGHGGSMPGYVAGLAVHRPTGTAVVNFANSYGLRGHHIGALGREALTLVLDAEPAAPA
                     PWRPADPPAADVAALTGRWWWMGGEYEFRVDAAGDLVGGQVGRPQLRFTREGPDRWRGR
                     AGSQDGEILTVIRDESGTPVALDIATFVLTRTPDELP"
     gene            complement(19458..20270)
                     /db_xref="GeneID:91356736"
                     /locus_tag="PVK74_RS11255"
                     /old_locus_tag="PVK74_11255"
     CDS             complement(19458..20270)
                     /codon_start=1
                     /db_xref="GeneID:91356736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018251506.1"
                     /locus_tag="PVK74_RS11255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_11255"
                     /product="DUF3097 domain-containing protein"
                     /protein_id="WP_210887153.1"
                     /transl_table=11
                     /translation="MAGRYDGDVLAGDWRRRKVTPEVDAEPDLVVEDADSGFCGAVVGF
                     DTGAVVLEDRHGRRRNFPLLPAAFLLDGRPVTLRRPARAPVPAARRRTASGSIAVDGVR
                     AQVAKASRIWVEGVHDAALVERIWGDDLRIEGVVVEPLDGIDALADEVRAFAPGPGRRL
                     GVLVDHLVPGSKESRIVARVNSPHVLVTGHPYVDVWQAVRPDALGIAAWPVVPPGQPWK
                     EGVCAALGVAEPADMWRHILSRVDSFADVETPLINAMERLIDFVTEPV"
     misc_feature    complement(20538..20552)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
ORIGIN
        1 tgggcgtcca cgatcagccc gtgcaccgcc tcggtgatcc ggacgaacgg ggtgccccgg
       61 cgcagctcga ccaggggcag gccgcggcgt tcggcggcgg cggccatcac ccggggcact
      121 ccggtgaggt accggcggcc cagctcgacc accagtccgg aggcgccgac gtcggccagg
      181 gtgccgatga actcgcgcag cccggcgtcg tcggccggca gcccgatccc ggtggtcagg
      241 accagttccc cgccgccgag cagggtggcg atgtcgggca cctcggcgat gtgcacccac
      301 cgcaccggcc ggtccagccc ggcgttcccg gcgaccaggc gtggcgcacc gtggcgcatc
      361 ggcaccaggt ccaggacctc acgcacggta gggaacacgg gcgacacgct accctgcgtc
      421 accgtcgttg ccgagggccg caccggccgg ctcgccgggg aggacgagcc ggccgggctg
      481 cgggatcagt cgacgccgaa ctccatggcg gcccggtcga gcgcctcgtc ctcggcggtg
      541 ggcacgcccc gggacgcgat ggcctcggcg ccgccctgcg gcatggcgcc gatcagcccg
      601 gtcgaggccg cctgggcggc gcccacgacc cgctgcgggt tcccgccgcc gaccatgccg
      661 acggaggcgt actgctccag cttggcgcga gagtcggcga tgtcgaggtt gcgcatggtg
      721 agctggccga tccggtcggc cgggccgaac gccgagtcct gggtgcgctc catcgacagc
      781 ttgtccgggt ggtagctgaa cgccgggccg gtggtgtcga ggatcgagta gtcctcgccc
      841 cggcgcagcc gcagcgtgac ctcgccggtg accgccgtgc cgacccagcg ctgcagcgac
      901 tcgcgcagca tcagcgcctg cgggtccagc cagcggccct cgtacatgag gcggccgagg
      961 cggcggccct cgttgtggta gttggcgagc gtgtcctcgt tgtggatggc gttgacgagc
     1021 cgctcgtagg cggcgtgcag cagcgccatg ccgggggcct cgtagatgcc ccggctcttg
     1081 gcctcgatga tccggttctc gatctggtcg gacatgccca ggccgtgccg gccgccgatg
     1141 gcgttggcct ccagcaccag gtcgacggcg ctgccgaact ccttgccgtt gatcgtcacc
     1201 gggcggccct ggtcgaagcc gatggtgacg tcctcggtgg ggatctccac ggacgggtcc
     1261 cagaacttca cgcccatgat cggctcgacc gtctcgatgc cggtgtccag gtgttcgagc
     1321 gtcttggcct cgtgggtggc gccccagatg ttggcgtcgg tggagtacgc cttctcggtg
     1381 ctgtcccggt agggcaggcc gcgctccagc agccactccg acatctcggt gcggccgccc
     1441 agttcggtga cgaagtcggt gtccagccac ggcttgtaga tccgcagctg cgggttggcc
     1501 agcaggccgt accggtagaa ccgctcgatg tcgttgccct tgaacgtcga gccgtcgccc
     1561 cagatctgca cgtcgtcggc gatcatcgcg cgcaccagca gcgtgccggt cacggcccgg
     1621 cccagcggcg tggtgttgaa gtaggcccgc ccgccggagc ggatgtggaa ggcgccgcag
     1681 gtcagcgccg ccagcccttc ctcgaccagg gcggcgcggc agtcgacgag gcgggcgacc
     1741 tcggcgccgt aggtgtgggc gcggccgggc accgaggcga tgtcgggctc gtcgtactgg
     1801 ccgatgtcgg cggtgtaggc gcacgggatg gcgcccttgt cgcgcatcca cgcgaccgcg
     1861 accgaggtgt cgaggccgcc ggagaaggcg atgccgacac gttcgccgat gggcagggag
     1921 gtgagaacct tggacacaag gaagattatg cacgccgtcg catggtcatg caagccggtc
     1981 gtcagagcgg gtcgtcccgc cccagctccc agaacgccac cgccgccgcg gcggccacgt
     2041 tcagcgagtc cacaccgcgc cgcatcggga tcaccacccg cacgtcgctg gcggcctgcg
     2101 ccgccgcggt cagtcccggc ccctccgccc cgagcagcaa cgccgcccgc tcgcgctgcg
     2161 ccggggtcag ccgctgcacc ggtacggcat caggcgcggg cgtcatcgcg agcacggtga
     2221 acccggccgc ccggacctgg tccagcccgc cgggccagct gtcgagcttc gcgtacggca
     2281 ccgcgaacac ctcgcccatg ctgacccgta cgctgcgccg gtagagcgga tcggcgcagg
     2341 tcggcgacag cagcaccgcg tcgacaccga gcgctgcggc gccccggaag atcgcgccca
     2401 ggttggtgtg gttgttgacg tcctccagga tcaccacccg ccgggcggcg gccagcacct
     2461 cgtcggccga gcgcagcggc ttgcggtgga acgacgcgag cacgccccgg tgcacgtgga
     2521 agccggtggc gcgctggagc acgtccggcg tggccgcgta caccggcgcg tcaccggtgt
     2581 ccagatcggc gagctggtcc acgcgcttgg cgtcgaccag gtacgaccgg gccgggtagc
     2641 cggcccgcag cgcccgccgc agcaccagct ccccctcggc gatgaacagc ccgtgcggcg
     2701 gttcccagcg ggtacgcagc tccacgtcgg tgagcgcgcg gtagtcggcg atccggtcgt
     2761 cgtcggggtc ggtgatctcg tggacgggca ccacgcgatt ctgcccggcc cgtcgggggc
     2821 gccccggcac gggccgggtt tccgccgccc cgggcgggga acggagcccg aaggccgacg
     2881 cgacggaggg accacgatgg gcgcggatca cgacggcaac ctcccccgcg acgccacagt
     2941 cgccgactac ctggtggccc ggctcgccga gtggggcgta catcgctact acggctaccc
     3001 gggcgacggg atcaacggca tgacctcggc gctgcaacgc gccgagggac gcgcccggtt
     3061 catccaggtc cggcacgagg agaccgccgg cttcgcggcc ggcgcgcacg tcaagtacgg
     3121 cggcggcccg ctcggctgcg tggtggtgac cagcggcccg ggcgcgatcc acgcgctcaa
     3181 cggcctctac gacgccaagc tcgaccacca gccggtggtg gcgctgctcg ggcacaccgc
     3241 gctgcccgcc gagggcggcg gctactacca ggaggtggac ctgctctcgc tctacaagga
     3301 cgtggcgtcg gccttcctgg cccagctcga cgatccgtcg caggcccggc acctggtgga
     3361 ccgggcctgc cgcaccgcgc tggcccggcg taccgtgacc gccctggtcc ttccctccga
     3421 cgtgcaggac ctgccggcgg tgccgcaccc gccgcacgcg cacggctact accacaccag
     3481 cgcggtgccg agcagcgagc cgacagtgcc gccggaggcc gacgtgcgcc gcgcggccga
     3541 ggtgctgcgc ggcggcgagc gggtggcgat gctggtcggg cagggcgcgc tgggcgccga
     3601 ggacgaggta cgccggatcg ccgaccggct cggcgccggc gtcgccaccg cgctgctcgg
     3661 cttcaccgcc gtcgaccacc ggcagccctg ggtgaccggc gcgatcggcc tgctcggcag
     3721 ccgccccagc tggcaactca tgcgcgagtg cgaccggctg ctgatcgtcg gcagccagat
     3781 gccgtactcg gagttctacc cgccggaggg gcaggcccgg gcggtgcaga tcgacatcga
     3841 cggcagccgg atggggctgc gctacccgac cgaggtgaac ctgaccggcg acgccggacc
     3901 gacgctgcgc gcactgctcc gggagctgga cccggggccg ggcccgaccg cctggcgggc
     3961 caccatcgcc gacgccaccg gcaagtggcg ggccgcgcaa cgcgaggtgg ccgcgcagcc
     4021 cgccgacccg gtcaacccgc agtcgctgtt cacctcgctc gacgacgcgc tgccggacga
     4081 cgccgtgctc gccgtggact gcggcaccgc cactgcctgg tacgcccggc acgtgcgcgt
     4141 gcgccccggc atgctggcca gcctctccgg cacgctgctg tccatgggcg gcggcatgcc
     4201 gtacgcgctg gcggcgaagt tcgcccaccc ggaccgcccg gtgatcgcgc tgctcggcga
     4261 cggcgcgatg cagatgaacg gcgtcaacga gctgatcact gtggcgaagt actggcggga
     4321 gtgggccgac ccccggttcg tggtgctcgt gctcaacaac cgtgacctcg cgttcgtcag
     4381 ctgggagcag cggtccagcg agggcacgcc gatgttcccg gacagccagg acctgccgga
     4441 cgtggcgtac cacaaatggg cggaggtgct gggcctcggc ggtgagctgg tcgactcccc
     4501 cgaccgggtg gacggcctgt ggcagcgggt gctcgacgcg gaccggccgg tggtggtcaa
     4561 cgcggtggtg gacccggccg agctgatgtt gccgccgcac ttcaccgccg agcaggcccg
     4621 caagaccgcc gcggcggtgc tgcgcgggga cagcgaccgg gccggcatcg tgcgccgcgg
     4681 cgtaccggcc gcgctcgcca cgtaccggcc ccgccgccgg ggccgctgag gcgtcaggcc
     4741 cgcgcgtagc gcagcagcac cgaccgcccg tcgaactgac gcgtctcgac cagccgcagg
     4801 tgctggcggg ccaggtcggg cagcacctgc cgtccgccgc cgagcaccac cgggtgcacg
     4861 atcacctcgt aggtgtcgac gagccccagc gcggccagcg ccgtcgccgc gccggtgccg
     4921 ccggtgacca gcaggtcgcc ggggaaccgc tcgcggacct cggcgaactc cttcgccagg
     4981 tcgccgccgc cgaccaccac cgcgccgtgg ggagccttgg cgagcgtgcg ggagaccacg
     5041 atcttcgggg tacgccgcca gatcggcgcg aacgccaggt cgtgcgggtg gtcggagatc
     5101 gactcgacct gcggccagta ggaggccatc atctcccaca cccgccgccc gtagacgaag
     5161 gcggaggccc gctcggccag gtcgatcgag tacgccgaca gctcctcccc catctccggc
     5221 cagtcgaact caccgttcgg gccctcgatg aagccgtcga ccgacgtgtg caccccgtag
     5281 atgacgttgc ccatgatgtg ttcctccgcg ttgcggcgcg acccggtcgg gcgcgctcgc
     5341 cggtgggtcg gagccgcccg gccggatccg acaacccggc cccgacgact cccggccagg
     5401 ctacggtccg gccagccgcc gctcgatctc gtccgccgtg gcggtggccc cgatccgggc
     5461 ggccacctcg tgggcgcgtc gccagacgtc ccgggccgcc tcggccccgg tcagccgctc
     5521 caccgcccgg gccaggtcca tcagggcctc cagctgcagc ggcgggctgg ccgtcaggtc
     5581 gtcggccgcc tgttcgagca ggacccgcgc ccgcgccggg tcgcccgaca tcaggctgat
     5641 ccgtccctgg gcgtaccggg cgtaggccag gtaggcggcg acccgcatct cgcgggcctg
     5701 ttccagggcg gtgtcggcgt atccggccgc ctcgcccagc cggccgtgcc ccgcgagcat
     5761 cgcggcgacc tcgctgagca gcgccacctc accgagccgg tcaccgtgcc gccggaccag
     5821 ttccagggcc tccaggtacg ccgcccgggc ctcgtccacc gcgccacggt ggtcgtgcca
     5881 gcggcccgac gcgcgcaggc cgaacgcgag cggccggggc gtgccggcgg cccgcagcag
     5941 cgcgacggcc cgggcgagcg tctccccggc ggccgggtcg ccttcctgga actggaggac
     6001 gcccagccgg gcgagtttcg gtccggcggc cacctcgtcg ccggcctcct ggtacagctc
     6061 gatggagcgg accaggctgg cgcgtgccgc cggacggtcg cccagccctt cgtacacctg
     6121 gttctcgacg ccggcgatgt cggcccgcag ccagggctgg tcgagcggct cggccgccgc
     6181 cgcggcggcc cgcgcgtagc cgagcgcggc ctccaggtca ctgcgtagca gggccgcgaa
     6241 cgccacgcag agccggagcc gggcgatccc ctccgggtgc cgccggcgct cggcggccgc
     6301 cagcccgatc tcggtgaccc gggtcaggtc gtccacccgg gcgtcgacga acaggtagta
     6361 gtcgcagtgc caggccagcg cccaggagta gtcctccagg ccgggcgtcg cggcggcctg
     6421 ctcgatgccg gcgagcaggg cggcccgttc ggcgccgaac cagcgtttcg ggtcgcgcag
     6481 gtgctcgccg gtgggcgccg gtgacctcgg caggtcggcg acgatgacgg cgccgccctc
     6541 ctggctcagc gccacgcggg cctgctcggt cagcgtcagc caggtgccga agacgcgccg
     6601 cagcacctcc ggccgctccc gcggcccctc ctcccgcgcg gcgcgctccc gggcgaacgc
     6661 gcggaccaga tcgtgcaggt gatagcggac ctggcccagc tcgtccggcc cggtcacctc
     6721 gaccaggttg gcctcgacca gaccggtgac cgcgttcgcc gcgcccgcct cgtcgtcgag
     6781 caggacggcg ggcagccacg gaggggcccg gtcgaggtcc agcacggcga accggcgcag
     6841 gagccggcgg gccggctcgt ccagcgccac gtacgccgag tggaacgccg cccgtatgct
     6901 gcggtcggcg cgggcgagat ggtccagccg gtgcgagagt tcggcgagct gcgccgccgc
     6961 ctgccgcagc gacagcacgc cgggtatcgc cagccgggcg cccgcgatcc gcaccgccag
     7021 cggcagcagc ccgcagtggt ggacgacgtc cgacgcggag ccgggctcgg cggcgacgcg
     7081 gtccgggccg atgatgccgg ccagcagccg cagcgcgtcc gcctcgggca gcggctccag
     7141 ccgcagctgg tgggcgccgt cgacgtcgac gagcgcgcgc cggctcgtga ccagcacgac
     7201 ggtgtccgta ccgggcagca gggggcgcac ctgcgccgcg tcggccgcgt tgtccagcag
     7261 caccactccg ggccgctcgg ccatcgcgcc ccggaacagc gcggcgcgtt cctccaggtc
     7321 cgccgggatc tgggcgccgg gcacgccgag cgcccgcagg aaccgcccga gcacctcgac
     7381 cgggggcgcc ggatggtcgt gcccgttcag gtcgacgtag aggtgcggac cggggtacgc
     7441 cgggccgagc tggtgggcga tccggaccgc gagggtggtc ttgccgacgc cgggcaggcc
     7501 gctgatcgcc gtcacggcga ccgccggccg ctccggaagc cactccagga ccgctgcgat
     7561 ctgttcctcc cggccgacga agtcggtgag gccggccgga agcatccgga ccggcgggcg
     7621 cgcggccccg tccggcccgg cggcaccgtg ttgtgcggcg cctccgtgct gtgcggcgat
     7681 tccgtgttgt gcggcggcgg cggcctggcc cggtccggag ccgggcgggc ggtccggcgg
     7741 cgcgacgacc gacccggcgt cgagcgccgg ccggaggctg gggtcgttgc gcaggatcag
     7801 gtcgcgcagc cggatcagct gggccgtggg gtcgatgccg agctcctcgg ccaggcggcg
     7861 gcgcaactgg tcgaaccggt ccagcgcctc gccctgccgg tccgccaggt agagggcccg
     7921 catgagctga cccacgagcg actcccgcca cgggtacacc tcgaccagct cggtgagccg
     7981 gccgatcacg ctgtcgtacc ggccgaggcc cagctccagg ccgaggcagc gctcgaccac
     8041 tgtcatccgc cgctcgtcga gacgctgcgc cgccgcggtg agcgccggcg tacgcaggcc
     8101 gtcgagcgcc ggaccgcgcc acatcgccag cgcctcgcgc agcccggaca caacctcctc
     8161 cggggcgccg ccccggtcga ggagcccttc cgcccggcgt acccgttcct cgaagacgtc
     8221 caggtcgagt tgaccctcgg cgacggtgag cagatatccg gagccgtggg tgccgatcac
     8281 gtcgccgggc agaccggcgg cgcgcagcgc ccgtcgcgcc gccgcgaccc ggttgcggac
     8341 ctggacgtcc gcgctcgccg gcggatggcc gccccaggcc gcgtccatga gacgggacac
     8401 cgggacgatc cggttggctt ccagcagcaa cgcggcgagc atggcctgac tgcgggggcc
     8461 accgacgcgg accgtccgat cgtcgaggca cacctcgacc gggccgagca gccgaaacat
     8521 gaccgccggc accattcgct ccccccgaag cgcgcggacc cgggcgacca cgtcaagatc
     8581 gccctccggc cccaccctag acgagttcgc gcgaggccag ggggtgacgc gtaccagcgg
     8641 tgaccggggg gacacaccac tgtgtccggt cgtcgtcggt ggtcagccga tcgggtccgg
     8701 cgcggcgtgc ggcgcttgac cggacgtgcc ccgggcctgg cgccgccggg agtgacggcg
     8761 gtagaacgtg accaggaaca tcgcctggag cgtgccctcg acgagcagga cgagcgcgcc
     8821 gtccacggcc gcgagcaggc ttccgccggt cgcgccggcc agcacggccg agccggcctg
     8881 gatcgcgccg tgcgcgacga tcgggattcc gaacaggacg aagctggaca acgcgacggc
     8941 gctgcccgcc accaccgcca gcgcgtagat ccgcaccgcg cgccgctcgt gcggcggaag
     9001 gacggcggtg gggtccccgg ccgacggcgt cacccggccg ggaagcgccg cgtgcagacc
     9061 ccggcgcagc aggtgccggg catacgcgaa gccgtcctgg aacaggttgc ggcaccgcag
     9121 caggtccagc aggacgaagt agcagtcggt acgcatgtag acgtgcagtt gcagcgccat
     9181 cgacatgacg atcaccagaa cgacggcgga cagcaggccg ccgaccagcg gatgcggccg
     9241 ggcgtacgcc atcaccagca gcgcggcgca caccacggcg gaatcccaga gcaggccgct
     9301 gaggtagacg cggtaccggt ggcggcgcgg caccgaccag atcgccgtca cgtcggtctc
     9361 caggaccaga tggtgcagcc gggtggcgaa ccggatccgg gccggcgcgt ccagcgaacg
     9421 ggccgccacc aggtgactga actcgtgcag caccgccgtc ccggagaaca gcacggtgtt
     9481 cacgagcacg gcgagaccga cgtagccggt ccagaagaag tcccggtacg acggcagcag
     9541 ctcgggacgg cgtaccactg tggccagcgt cgccgcgacc agcgcgacgt aggccacctt
     9601 cgccgccggg ccgaacagcc agcgcacgtg ccgggcccgc agccagggca ggtgcggccg
     9661 gtcctcgcgg cgggcgccgc cggtggggcg gccgtcgacc tcggccacca ggcccgcctc
     9721 ccgcagcgcg agcaccaggt ccacgaggtc gaggtccacg tcgtggtcgg cggcgatccg
     9781 ttcctcggcc acgccgatcg gcgctccgcc gtcgagcagc tcgacggcgc ggacgccgat
     9841 cgcgggcagt tccacgaact cgccgacctc cggccggccc accaccaccg agtccgggtc
     9901 gtcgtcggac ggccggatcc gcagcgggtg gaaccgtacc cgcgtcgcgg cgcccagatc
     9961 cggcgccgcc tcgaccccgg tggtcgtcat cgcccggtcc tcacgcgccg cgcggaccgc
    10021 acgaggggca gtccgggtcc cgcggcacgt cgatgaagta gtggtggtcc cagcgcgcgg
    10081 cgttctggtg gaagacccgg ccggcgacct gctggggcag cccgccgagg tggtagagca
    10141 cctccagcgc gcagaggtga ccggtcacgt tcgcggtggc ggcgatcacc gcgttcggtc
    10201 gttccccgcc gcgcagcggc gtgccgtcgg tctggatctc gtgcttgtcc ggccgccgcc
    10261 gcaggcaggt gtagcacccg gtgcggcccg ggaggaacga gccgacgacc gtcatcggcc
    10321 cggtgtagag cgccatgaac cacggcgtgc cggtacgcag cgccgcctcg ttcgtccagt
    10381 cctggatctg gtcgacgggc cggtccgcgc agaggacgaa ggcgtcccgc ccgttcatca
    10441 gcggcactag gtcgtcggcg gagcggaccc ggcactcctc cccggtgacg tcgacgtgcg
    10501 agttcatcgc ccgcagccgg tccacggcga ccttcacctt cggctggccg aggtcgctct
    10561 cggtgtagag cagctggcgg gtcaggttcg gctggtcgat cacgtcgaag tcggcgcagt
    10621 gcaggccgcc gacgccgctg gcgacgagtc cggccgcgac cgccgtgccg gtgccgccga
    10681 gaccgagtac ggagacccgc gcccgcccga tacgcgcctg cacctcgaag ggcgagctgc
    10741 ggggctgggt gtcgatccag gcgtagaagt gccgggcccg gtcgtagcgc tgcgcggcct
    10801 ccgcggtgaa cccgtcgggc agcggggccg ccgcgtcctc gacgaagccc tgcgcgatga
    10861 gctgctccac cacctcgcgg acgctgtcct cgtcgatgcc cgggtgcgtc tcggcgaggt
    10921 ccgcgcagac ctcccacacg taccgggtgc cgtccagcaa cgtcaggatg cgggcgatcg
    10981 tgccgtcctc gtcgtcctgg atctccgacg cgacgccgta ctgcatcaga ccgatgatca
    11041 gccggttccc cggcagcgtg tagggctcgt ggacactctt gacgcgcggc ttgagcatgg
    11101 gaccgcaacc tcactaacgc tcggcggaag acgggaaagc ggcaccccgg ccgccgcggt
    11161 aggtggcggc gaccggggtg ccggcgcgga tcaggcgccg ttgctctcgc ggatgacggt
    11221 ggtctccagc cgctccagct tgcggacctt cagcgagagc ttcttcttgc cggcctgctc
    11281 gatcgtggcc ttctccatgg acgcctcctc gattcgggta cgccttccgt ggtgccggaa
    11341 ggcgagccca agcctgtcgc ccggcgtcac cggtcgatca caagtcgatc atcagcggcc
    11401 gttgatgatc gccgccagca tccgggtgtg tggcccgacc tgtgatgatc gcgttgctcg
    11461 gcgtcgacgg ctccggcagg accaaccagg ccgaggcgct ggcggagtgg ctgcgccggc
    11521 ggggcgtccg ggcgcggtac ttcgagaacg ccggtgggag gccactgtgg aaccggctgg
    11581 cccgcgcact cggccgggcc gacgggttgg cgctgttcgg ccgtaccgtc catccggcgc
    11641 tggaggcgac ggtgcgggcg gcggcggtgg cccgcctgac cggccgggtc gcggtgctgg
    11701 accggtggac ctggtgccag gacgtgatca tggcggcccg gggcgaccca ggcggcgggt
    11761 ggccgcgcgc cgggggcggc gttaagtgag tgtttgagat tccggctcag gtgtgggttg
    11821 cctgggccgg tttcgtgtgt cgggccaggc gggtgaccat gacgtggatc atggcccagg
    11881 tgacgaaggc ggcgtggctt gtgggtaggt gttcgtagtc gcggacgcag cggcgtttct
    11941 tgctgatcca ggcgaaggtg cgttcgacga cccagcgtcg gggcagcacg acgaaggtgt
    12001 gttgtccggg gagtttgtgg accaggtgca cggtgaggtc gagggcgtgg cgggcccagg
    12061 tgctcagggt gccgatgtag ccgccgtctg cccagagcag gcgtaggcgg gggtggaaca
    12121 gccgggtgcg ccagagcagg tcacgggcga tggtgcggtc gttgacgtgc gcgccggtga
    12181 tcatgacggc caggagcagg cccatggtgt ccacgacgat gtggcgttta cggccgttga
    12241 ccttcttcgc gacgtcgaaa ccgcggctgt gtcggggcac ggtgtccgcg gcgcgcaccg
    12301 actgagaatc gatcgctccg gcgctgggat gcgcgtgccg tccggcggcg gtacggcact
    12361 gctcccgcaa ccggtcgtgc agacgcatca acgtgtggtc atcgcgccat cgagcgaacc
    12421 accagtacac cgtccccggg ggcgggaact cccgcggcag ggcccgccac ggacaaccgg
    12481 tgcaggccac atacaagatc gccgtgacga ttgcccgcat cggatgcgac ggcggccgcc
    12541 cccgccgacc gaccgacgcc ggcgtgacca gcggcgcgat caacgcccac tgcgcatcgg
    12601 tcagatcact gggataccgc cgccgcaccg cccgttcccg ttcccgccgc acccgctgcg
    12661 acggataacg gcggggcgac gcggacggcg tgacagtgat cgggtacaac gtcatcagaa
    12721 ggccctcggt atggaaacgg ttggctcgac accaccggac ctaccgaggg ccttccctca
    12781 cctcaacccg acacgccgcc gcaccccaaa tctcaaacac tcactaagaa ggggcccctt
    12841 tactaccgga ggcgttaaga aggggccctt ccttacccgc ggtcgcgcag ccagcgcagc
    12901 acgtcggagg gcagctcgcg gtcctcgcgc tgctcgcggc ggtccggctc ggtccgccgg
    12961 ggcggctgcg gacgctgcgg gtcgccgacc agcgcccggc tcggcgcggt gaagtcggcc
    13021 accggcttgc cggtgaccgc tgtcctgatg gtccgcgcga ccgcgtcgat caccttcgcc
    13081 tgcacggcgg agccgaccag gtcggtgacg tcgtccgggt tggcggcgat gccggccacg
    13141 gcgacctgcg gggtgtaccc gacgaacgtc tccgtggcgt tccgctccga gctgccggtc
    13201 ttgccggcga ccgggcggcc gacgatcgag tcgacggcgg tggcggtgcc gccgttgcac
    13261 tgcccgaacg ccgactgctg gccgaccggg cagcgggccg cgtcggtggc ggcccgggcc
    13321 acgtccgggt cgaggacccg cttgcactcc ggttgcccca cgtcgacggt gccgccgtcg
    13381 ggcgtggtca ccgagaccac cggcagcggc gtgcagtacg tgccctcggc ggccaccgtc
    13441 gcgtacgcgt tcgccaggtc gagcggggtg gtggcggcca cgccgagcgt gaacgcgccc
    13501 cagtcggcgg cgtggtcgcg ggcgaacgtg gcgtcggagt cggcccggaa ggtgatgccg
    13561 aggcgctgcg ccatctccac caccttgtcc tcgccgacct gttcggccag ccagacgaag
    13621 tacgtgttga cggagcggcc gaagccgtcc cacatcatcc ggtagccgtc catccactgc
    13681 gggttggcgt tcgccgggca ccaggtgccg tcgcagttgc cttcgtcgtc cgaggcgtac
    13741 cgggtgggca gccggctggg ggcgtcgaag ccggtggaca gcggcttgcc ggcctccagc
    13801 gccgccagca tggtgaacat cttgaacgtc gagccggcct ggtagccgtc gacgctggcg
    13861 ccgccggaga tcagcgggtt gaccgtgttc gggtggttgg cctgcccgtc cgggttggcg
    13921 tcgaggctgt agtgccggtt caccgccatg gcgagcaccc ggccggtgcc gggctcgacc
    13981 gccgcgatcg gcagcgcgcg cttgttgccg tacccgtaga ccttggtggc ctgctcctgc
    14041 gcggtctcct ggatcttcgc atccagcgtg gtgacgacgc ggtagccgcc ccggcgcagc
    14101 gcctgctcgc gctcctcggg ggtggcgccg aacgcgggct gggtgagcca ccagcggcgc
    14161 aggtagtcgc agaagaagcc ccagtcgtcg tgcccctggg ccgtggcggt gcagccgttg
    14221 ggctgggcgg tcgggcgcag cgtgggcgcc tgcgccttcg ccgccgcggc ctgctgggcg
    14281 gtgatcgcgc cggtctcggc catcgcgtcc agcacgtacg cccggcgggc cagcgcctgg
    14341 tccaggtcgc cgtcgatcgg gctgtacgcc tccggcgact ggaccagacc ggccagcagc
    14401 gccgcctcgc ccagcgtcag gtcggccggc gccttgccga agtagcgctg gctggcggcg
    14461 gcgacgccgt acgcgccgga gccgaagtac gcgatgttga ggtagcggtt gaggatctcg
    14521 tccttggaca gcgactgctc cagcgcgttc gcgtaccgga tctcctggag cttgcgcccg
    14581 acggtctgct cggtggcggc ctgccgctcc gccggcgtgc ggttcgggtc ggtcttgagc
    14641 acgttgcgga cgtactgcat ggtcagcgtg gagccgccct gctcggtgcc gccgcccttg
    14701 acgttcgcca ccagcgcgcg ggcgatgccg cgcaggtccg cgccgccgtg cgagtagaac
    14761 cgccggtcct cggccgcgat gatcgcctgc cgcatcaccg gggcgatctc gtccagcgac
    14821 acgtcggtgc ggttcacgtc gtagaacgtg gtgatcagcg tcttgccgtc gttggcgtag
    14881 aggtaggagc gctgcggctg ggacggggtg cgcagcgcgt cgggcaggtc cgcgtacgcg
    14941 ccgagcgccg cccgggcggc gaacccgccg agcagtccgg cgggaagcgc ggcgaccgcg
    15001 aggacgagcc cggcgagcag gccggccagc agcacggtga acagccgcga cagcggcgac
    15061 ctgggtgacg gcatgaaggc aaggattgcc acgaaagccg cctaccggcc acctcgccag
    15121 gcaactgtca gttacttcac ggcggccgcc cagctgaaga accggtcaac cggcgccgag
    15181 tgggcccttc ggtgacgcgg gcggcaccgg agcggcggcg acgctggcgg ccgccgcgtc
    15241 ccgggcgatg gtctcgggca ccaggcggcc gctgcggtag ccgatgccga tgccggcgac
    15301 cagcacgaag atcgcgccga acgtctgcag cgagccgatc agcgcgccgc ccaggccgag
    15361 cagcggggcg gcgatcatca gcatggtccc gtcgccgtag gagaacatcc cggaccgggc
    15421 caccgaccag ccggtcagga accagcccac gctgtagagc gtggcgccga acagcacgat
    15481 gccgcgcgcg gtcacgccga acaccggcgt ctgctcggcc agcccggcga acggcagcat
    15541 cagcaccatc ccgccgatgc tggcgagcag cccggccagc gcgacgcggc ggcagcgggt
    15601 ggcggcgagc aggccggtga gcgcgagcag ggcgagcagc ccgagccaca ccgaggcgac
    15661 ccagccgacc aggtagagcg gccggccgtc ggccgggtac gggtcgttgc ccaccccgcc
    15721 gtcgctggcc atcgccacca ggccgtagag caccgcgtac gcgggcagca gccagaccgc
    15781 cgcgcgggcg aaccggcgga tcgaccaggc ccaggtcgcg tcggtggcgg gcgcgcccgg
    15841 gccgggctcg gagacgaacg gcaggacccc gaacccccct ccggtacgcc gggagccgat
    15901 cggcccggcg gggtcgtgcg cgccggggac cggggtacgg gagaacagcc ggttcgccgg
    15961 gtccttcatg cgtcacctcg ttcgcgccgc gggtggcccg ggacacgcaa cggcgctccg
    16021 gccctgctca ccacccgtcc tcaagaccga tggtggcagt cgccggagcg ccgtatgagg
    16081 acttttcgga tttgccggtc agccccgctc gcgctggtcc gccgggtcgt tcaccaggct
    16141 ggccggcgac accggctccg gcgcgggcag gccctgcggg gcgttgccgc cggtggcctg
    16201 cgcctcggcc acccgtacct cgttgtggat ctcctgggcc gcgacggccg cggcctgggc
    16261 ggcctcggcg gcctcccgct cgacctcacc ggcgctgcgg gcggcctccg gcgacggcac
    16321 gtcgccggcc atgttggcca gcccgcccag cgcgccgccc atgccctcca gggccttggt
    16381 cagctcggtc gggacgatcc agaccttgtt ggcagtgccg ttggcgatct gcggcagcgc
    16441 ctggaggtac tggtaggcca gcaccttctg gctcgggttg gcggtgtgga tcgcgtcgaa
    16501 gacggtacgg atcgccttgg cctggccctc cgcctggagg atccgggcct gccggtcacc
    16561 gtcggcgcgc agcaccgcgg cctgcttctc accctcggcg gtgaggatct gcgactgctt
    16621 gtggccctcg gcgttgagga tcgcggcgcg gcggtcccgc tcggcgcgca tctgcttctc
    16681 catcgagtcg cggatgctcg gcggcggctc gatcgccttg atctcgaccc gggtcacctt
    16741 gatgccccag cggccggtgg tctcgtccag cacgccggac aggtgccggt tgatctcctc
    16801 gcggctggtc agcgcgcgct ccaggtccag cgagccgatc acgttacgca gcgtggtgac
    16861 ggtgagctgc tcgatcgcct ggaggaagtt ggagatctcg taggtggcgc gaaccgagtc
    16921 gaccaccttg aagtagagga ccgtgtcgat cgagacgacc aggttgtcgg aggtgatcac
    16981 cggctggggc gggaagctga ccacctgctc acgcatgtcg accttggtgc gtaccgcgtc
    17041 gacgaacggc accagcaggt tcaggcccgg gttcagcgtg cgcttgtagc ggcccagccg
    17101 ctccaccacg tcctgccgct gctgcggcac gatccgcacc gccttgaaca gcgtcaccac
    17161 accgatcaac gccaccgcga tcatcaggat cgccagaaac tccataccgt tcaccttttc
    17221 gcttcgggca gctcgcccgg ggtggaaatg tcgtcctgcc ataccagggc ggtagcgccc
    17281 cgaaccttga tcacctgcac ccgctcaccc tcggcgtacg agcgcgtcgc gtcgtacgag
    17341 cgggccgtcc acagctcacc gtcgatcttg atcatcccgc gctcggagtc gaccggctcc
    17401 aggaccacag cggtggcccc ctccagcgcc tccaccccga acggctgctc cccggtctcg
    17461 atcgccggcc gcgcgtgccg ccggaccacc ggacggacca ccgccaccga caacgccgac
    17521 accaccgcga agatcaccgc ctgcagcgcc accggcgcgc cgagcgccgc ggcgccggcc
    17581 gcggcgaacg ccccgacccc gaacatgatc aggaagagcg tcgtcgtaaa gatctcggcg
    17641 accgccaata ccacacccag aacgatccag aacacggcgt ccacgagaac aatcctgaca
    17701 cgtcaacgca cgtgtcatcg aactgtcatg atcgctaggc tcggctcggc gtaccgcgcc
    17761 caccgccgac gaggaggacg agatgcccct gctgcccgag accgcgcgtc aggtggacct
    17821 gctggtcgcc cgggcccagg ccgaggggcg gggcccctca ctcgcgctcg gcgtggtccg
    17881 cgacggccgg ctggcgcacc tcgccgtcgc cggtgagacg ccccgccccg acgccgacct
    17941 gcagtaccgg atcggctcga tcaccaagac catgaccgcg gtgctggtga tgcagcagcg
    18001 cgacgccggc cggctgtcac tggacgaccc gctggacgcc cacctgcccg gcaccccggt
    18061 cggctcggtg acggtgcgcc agctcctcgg ccacgtcagc ggcctgcaac gcgagccgga
    18121 cggcgactgg tgggagcggg tcgggggcac ggacctggac accctgctcg ccgggctgac
    18181 ctcggacaag atcgcctacc cgccgcactt cgtctaccac tactcgaacc tggcgtacgg
    18241 actgctcggc gccgcgctgg aacggatcac cggcacgccc tgggcggagc tgctgaccga
    18301 gcggctgctg gccccgctgg gcatgcgccg caccacgtac caccccaccg agccgtacgc
    18361 ccgcggctac gtcgtccacc cgtggcacga gacgctgcgg gaggagccgc gcaccgacac
    18421 cgcggcgatg gcgccggccg gccagctctg gtccacggtc gaggacctgg gccgctgggc
    18481 cacgttcctg gccgacccgg acccggcgct gctctccccc gccacgctca ccgagatgtg
    18541 cgcccccatg gtcatcaacg acctcgactc gtggaccggc gggcacggcc tcggcatcga
    18601 gctctaccgg gtcggcgacc gggtgtacgt cggacacggc ggctccatgc ccgggtacgt
    18661 cgccggcctg gccgtgcacc ggcccacagg caccgccgtg gtcaacttcg ccaactcgta
    18721 cgggctgcgc ggccaccaca tcggcgcgct cggccgggag gcgctcacac tggtgctgga
    18781 cgccgaaccg gccgcgcccg ccccctggcg cccggccgac ccgcccgccg ccgacgtggc
    18841 cgcgctgacc gggcgctggt ggtggatggg cggcgagtac gagttccgcg tcgacgccgc
    18901 cggtgacctg gtcggcggcc aggtgggcag gccgcagctg cgcttcaccc gcgagggccc
    18961 ggaccggtgg cggggccgcg caggctccca ggacggcgag atcctgacgg tgatccgcga
    19021 cgaatcaggc accccggtag ccctggacat agccaccttc gtcctgaccc gaacccccga
    19081 cgagctcccg taactcccgc ccccgccccg ccccaccccc gccccgccga tcttgcactt
    19141 gtggccctca tttcgccccg ctatgcccga tccgcggggg ccacaactcc atgatcgacg
    19201 cacacccgca ccgcccaccc cgtgatcaag gagttcgcgt ccgcgttgat ctccaattca
    19261 cccgcaaact ccttgatcac cctggcgggg gcgggcgggg cgcggggggc cgggggcgcg
    19321 aggggccggg gcgggggcgg gtgcgggtgg cgctggcgca cggcggggcc gggggcgacc
    19381 gtgaccggcg cagggatcaa gcctgaccgc ccggagccgg gcacggtcgc ccccggccct
    19441 caaccgcaac cgacctctca gacaggctcg gtgacgaagt cgatcaaccg ctccatcgcg
    19501 ttgatcagcg gcgtctccac gtcggcgaaa ctgtccaccc gggacaggat gtgccgccac
    19561 atgtcagccg gctcggccac cccgagcgcc gcgcagaccc cctccttcca gggctgcccc
    19621 ggcggcacca caggccaggc cgcgatgccc agggcgtccg ggcgtaccgc ctgccacacg
    19681 tcgacgtacg ggtgcccggt gaccagcacg tgcggcgagt tcacccgggc cacgatccgg
    19741 ctctccttcg agccgggcac caggtggtcg accagtacgc cgagtcggcg gccggggccg
    19801 ggcgcgaacg cgcgtacctc gtcggcgagc gcgtcgatgc cgtccagcgg ctccaccacg
    19861 acgccttcga tgcgcaggtc gtcgccccag atccgctcga ccagcgcggc gtcgtgcacg
    19921 ccctcgaccc agatccggct ggccttggcg acctgcgccc gtacgccgtc cacagcgatc
    19981 gagccggacg cggtacggcg gcgcgcggcg ggcaccgggg cgcgtgccgg ccgccgcagc
    20041 gtgaccggcc ggccgtcgag caggaacgcg gcgggcagca gcgggaagtt tcgccgtcgc
    20101 ccgtgccggt cctccagcac caccgcgccg gtgtcgaagc cgaccaccgc gccgcagaac
    20161 ccggagtcgg cgtcctcgac caccaggtcc ggctcggcgt cgacctcggg ggtcaccttc
    20221 cgtcgccgcc agtcgccggc cagcacgtcg ccgtcgtatc gccccgccat gccggagacg
    20281 ctagccacga cctcggcgtg tcgctcgccg acgcgccgac cggggcgtca tccgtcggca
    20341 cgaaacggtg cgaaggggtt agttgggggc aggtcgcgcc accggagcgg cagccgagac
    20401 agcagcggcg cggagcacgt accctttcgg catgtcctcc cccgcagcgg gcgcggccac
    20461 actggctccg cgccggtcga gccggttcgt cgcctgggtg cgtgcctggc gagccggcct
    20521 ggtgccgttc gacgaggtgg ccgacgcggt cgccggcgac gaggagcacc tggtcgccga
    20581 cgcacccggc acctggaccg acgtgtccct gcgggaggcg ctgcccagcc tggccaagca
    20641 ctccccggac gacatccgcc tggtgctgcc cgcgccgggc gacccgcgcg gcctgcccgg
    20701 cccgggcgcg ttcgccgggg ccgcgctggt ggccggcgag gcggtggtgg ccagcggcat
    20761 ggggttggtg ccggaggtcc gcacgcacac ctccgggtcg gggatgacct gggagacagt
    20821 gctgtggcgg gtccacccgc tgccggcgga cgcgccgaag gcgtccctgt ccacgcccgg
    20881 cgcggcggag gccgaggcgg aactctccgc ggtgctcgcc gagacgacag ccacgctgac
    20941 ccgcctcgac gtcgcgcagt ggcggcccga gctggccggt gcgctcgccg cgttgcgccg
    21001 cccggacgga ggcaccgacc tgccgcccgg cttcgacccg cgggcccgcc ggctgttcgc
    21061 gcgcgccgcc gtactcgatc gggtgctggc gctggccg
//
