LOCUS       NZ_CP118233            21185 bp    DNA     circular CON 13-JUL-2024
DEFINITION  Micromonospora chalcea strain 1K05785M01 chromosome, complete
            genome.
ACCESSION   NZ_CP118233
VERSION     NZ_CP118233.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora chalcea
  ORGANISM  Micromonospora chalcea
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Study on the Growth Characteristics and Drug Resistance Related
            Proteins of Micromonospora chalcea MCCC 1K05785
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2023) Tianjin University, Tianjin University,
            Weijinlu Nub92, Tianjin, Tianjin 300072, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2022
            Assembly Method                   :: CLC NGS Cell v. 5.29
            Assembly Name                     :: TJU-micro-1.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028768405.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 23:01:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,224
            CDSs (total)                      :: 6,161
            Genes (coding)                    :: 6,110
            CDSs (with protein)               :: 6,110
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 51
            CDSs (without protein)            :: 51
            Pseudo Genes (ambiguous residues) :: 0 of 51
            Pseudo Genes (frameshifted)       :: 16 of 51
            Pseudo Genes (incomplete)         :: 40 of 51
            Pseudo Genes (internal stop)      :: 2 of 51
            Pseudo Genes (multiple problems)  :: 7 of 51
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:37:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1413169
            Orig. end                         :: 1434354
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP118233.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21185
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="8"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21185
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21185
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11185](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11185)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(250..263)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.12"
                     /tool="antismash"
     gene            complement(934..1923)
                     /db_xref="GeneID:91355814"
                     /locus_tag="PVK74_RS06645"
                     /old_locus_tag="PVK74_06645"
     CDS             complement(934..1923)
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355814"
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018784707.1"
                     /locus_tag="PVK74_RS06645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06645"
                     /product="ABC transporter permease"
                     /protein_id="WP_043330115.1"
                     /transl_table=11
                     /translation="MLRFVVRRLLVAALTLVVISLVTFGLFFAVPSSPAKVMCGKNCTA
                     EDIAQVERRLGIDQPLPRQYADFVGGVFAGRTYGEGDFRQDCPAPCLGYSFRNNQPVTE
                     IVAQRAPVTFSIVLGGAVLWLGLGISLGMVSALRRGTAFDRAAIGVTLAGASMQVYFFG
                     LILLYLLVYSTGLLPFPSYTPLTESPARWAAGLLLPWMTLGFLNSALYARLSRAQMLET
                     LSEDFIRTARAKGLPARQVHTRHALRAAITPIVTIAGLDIGTSLGGTFITETIFGLQGL
                     GKATVEAVQFLNLPVVMATVLLAAVFIVVANIVVDVLYAVIDPRVRLG"
     gene            complement(1989..3734)
                     /db_xref="GeneID:91355815"
                     /locus_tag="PVK74_RS06650"
                     /old_locus_tag="PVK74_06650"
     CDS             complement(1989..3734)
                     /codon_start=1
                     /db_xref="GeneID:91355815"
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286428.1"
                     /locus_tag="PVK74_RS06650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06650"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_064445899.1"
                     /transl_table=11
                     /translation="MRARTRTLTGVLAAAALAAAGCNPTPDDSGGDDQKTKTQSGSISY
                     EAADNQGPAKPVDGASRGGTLTVMQPADFEHLDPARNYVNVQQVAGGMLYRPLNGYKED
                     GTGKLLLVGDLATNPGKDVDGDCKVWEFTLRDGVRYEDGTPVSSKDVAHGIARSFAANL
                     NEGPHYIQQWLYPGGAYNATYKGPYDGGKPVPDGVTTPDDRTIRFTFPQPHCDMPYAAA
                     LPTSAPVPAAKDTRANYDLRPFSSGPYRVKSYQRDVSLELERNPNWDPATDPLRNAYPD
                     TVRMTFGLEQAQIAERLVADGPADQAALSWSDVPPSVLPRTTGAGVADRVVRGPTQYNW
                     VLSINTQRVTDLNVRRALNYAVDKDALLKVLGGQAAGTPATTLMSPTTAGFVPYDVFNA
                     PVTGDKAKTAELLAGKRPKLVLAHSSLELRTQQAEALRKNLTDMGFDIVMKPIDNSSYY
                     DEVGRKDNPYDLYLTGWGSDWPTGSTVIPPVYDGREIVAEGNQNLSYLNEASVGAEIDR
                     VRALPAAEQDAGWMALDRMIMEKYAPVVPCYYDATYELHGSKVGNAFLSDAFGIISLNG
                     IYVKK"
     gene            complement(3794..4825)
                     /db_xref="GeneID:91355816"
                     /locus_tag="PVK74_RS06655"
                     /old_locus_tag="PVK74_06655"
     CDS             complement(3794..4825)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355816"
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286429.1"
                     /locus_tag="PVK74_RS06655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06655"
                     /product="ABC transporter permease"
                     /protein_id="WP_210882755.1"
                     /transl_table=11
                     /translation="MSDLSHPPPRTTAAEATIPGPEIQADSEPVGRTAEFVGRSPNQLA
                     WLRLKRDRTARVSALTLLVAAVVALGAPLLGRLTGIDPTDKFVDRLNDFGMPIGYAGGI
                     SSDHWLGLEPGSGRDILMQLVYGLRTSLFIAFTSALLASCIGVAVGVLAGWARGWLDSL
                     VNWLIDLTLAFPFLIFALAVIPILQDRFYSDREAPSPAFRVALIVATFGLFSWTYTARL
                     VRGQVISLREREFVDAARAAGAGTAHILLRQLLPNIWAPILVTVSLMVPQFIAIEAALA
                     FVNIGVTEPTPDLGRMIFNSIGYVASDPWYTLFPGLTIFLLVLAFNLLGDALRDSLDPR
                     STR"
     misc_feature    complement(4922..4938)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.15"
                     /tool="antismash"
     misc_feature    complement(5020..5031)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.58"
                     /tool="antismash"
     misc_feature    5114..5127
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.31"
                     /tool="antismash"
     gene            5236..5628
                     /db_xref="GeneID:91355817"
                     /locus_tag="PVK74_RS06660"
                     /old_locus_tag="PVK74_06660"
     CDS             5236..5628
                     /GO_function="GO:0004867 - serine-type endopeptidase
                     inhibitor activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286430.1"
                     /locus_tag="PVK74_RS06660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06660"
                     /product="SSI family serine proteinase inhibitor"
                     /protein_id="WP_274478504.1"
                     /transl_table=11
                     /translation="MPFARRTAALALVAALGAPASPAQAAPRPGPQTPSVLLLTVDDGA
                     GVHATVLTCGPTGGLHPDPFTACRLVARVDGDLDALDVDGAPCTSQYAPVVARAAGFWQ
                     ARPVSYTRTFANPCLMQRTTASLFTF"
     gene            5744..6628
                     /db_xref="GeneID:91355818"
                     /locus_tag="PVK74_RS06665"
                     /old_locus_tag="PVK74_06665"
     CDS             5744..6628
                     /codon_start=1
                     /db_xref="GeneID:91355818"
                     /gene_functions="other (smcogs) SMCOG1286: Pentapeptide
                     repeat protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286431.1"
                     /locus_tag="PVK74_RS06665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06665"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_274479254.1"
                     /transl_table=11
                     /translation="MVRVDGGAVEARTVGGGRELRADCSRCAGVCCVAPAFTASADFAI
                     DKPAGRPCPNLGADFRCGIHTELRQRGFPGCTVFDCFGAGQHLTRHTFAGRDWRADPAT
                     AARMFDTFAVLRPLHELLWYLTEAVRLTPPGPLRDELTAVLDETGRLADGTPDELLALD
                     VDAHRDRANRLLSRAAEQARAGRAGPDRRGATLIAVDLRRTPLAGANLRGACLIGADLR
                     GVRLGAADLTGADLRGADLRGADLSECLFTHQSQLDAARGDHRTVLPPGLRRPAHWSLT
                     LTPARPRPRPRRR"
     gene            6819..7073
                     /db_xref="GeneID:91355819"
                     /locus_tag="PVK74_RS06670"
                     /old_locus_tag="PVK74_06670"
     CDS             6819..7073
                     /codon_start=1
                     /db_xref="GeneID:91355819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013476716.1"
                     /locus_tag="PVK74_RS06670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06670"
                     /product="preprotein translocase YidC"
                     /protein_id="WP_104115932.1"
                     /transl_table=11
                     /translation="MGYRARDGEEPVDPAHAEDEAGQVPLVQTAADTDVPAPAPGAPKP
                     DEVTEDDGSGMAGGASGSSSGGSSMPTHPDAARGRDAAG"
     misc_feature    complement(7104..7117)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.24"
                     /tool="antismash"
     gene            7147..7407
                     /db_xref="GeneID:91355820"
                     /locus_tag="PVK74_RS06675"
                     /old_locus_tag="PVK74_06675"
     CDS             7147..7407
                     /codon_start=1
                     /db_xref="GeneID:91355820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286433.1"
                     /locus_tag="PVK74_RS06675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06675"
                     /product="hypothetical protein"
                     /protein_id="WP_043323893.1"
                     /transl_table=11
                     /translation="MTSEESFGRAAGDEPDGVTAYEASLRPPGESLHTTDDTGDDFADL
                     PAEDRRSAREVSRAGYDVDAVSGTGDPSEEPEEIEEGRPLR"
     gene            complement(7326..7889)
                     /db_xref="GeneID:91355821"
                     /gene="rnhA"
                     /locus_tag="PVK74_RS06680"
                     /old_locus_tag="PVK74_06680"
     CDS             complement(7326..7889)
                     /EC_number="3.1.26.4"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355821"
                     /gene="rnhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286434.1"
                     /locus_tag="PVK74_RS06680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06680"
                     /product="ribonuclease HI"
                     /protein_id="WP_043323891.1"
                     /transl_table=11
                     /translation="MAEAETGRVVEIWTDGACSGNPGPGGWGAVLRWGGHERELCGGEA
                     TPTTNNRMELTAAIRALESLTRPVTVRLHTDSTYVRNGITGWLNAWKRNGWLTAAKQPV
                     KNADLWQALEAACARHDVTWLWVKGHNGHPENERADALANRGMTEARSGTAAAPRTRQR
                     SGRPSSISSGSSDGSPVPETASTS"
     gene            7960..8748
                     /db_xref="GeneID:91355822"
                     /locus_tag="PVK74_RS06685"
                     /old_locus_tag="PVK74_06685"
     CDS             7960..8748
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286435.1"
                     /locus_tag="PVK74_RS06685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06685"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_274478508.1"
                     /transl_table=11
                     /translation="MTTPPDFATLCNFRDLGGWRTGDGRTVARGRLYRSDSLAKLAGDD
                     LQRFAALGVRTVIDLRYPWEIADRGRAPESLGVTWHNLSIEHRPYVQADIDPDVDPWRY
                     LADRYAEVAEDGVAELRRAVEVIADGEHPLVFHCASGKDRTGLLAALVLSLLGVDDDQI
                     AADFALTEHATDRLVAEWRDRNGGATPGWPAYGRAPAEVIRLVLADLRAAHGSVHGYVT
                     GRLGVDAQTIDALRARLLTGDTDPLPTQGATGATPTTLAR"
     gene            8840..9955
                     /db_xref="GeneID:91355823"
                     /locus_tag="PVK74_RS06690"
                     /old_locus_tag="PVK74_06690"
     CDS             8840..9955
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355823"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013476713.1"
                     /locus_tag="PVK74_RS06690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06690"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_274478510.1"
                     /transl_table=11
                     /translation="MDTRWDGLRAEVRDTIDELVSSGWEAGVQVAAYLDGVAIVSEHAG
                     LADTTTGRPMTADTPVHAVSTGKGLTATVVHVLAERGRLDYDLPLAAVWPEFARHGKDA
                     ITLRHVLTHTAGLPALPAGVTPEDFTDWTRMCELLADARPLWAPGERLAYHAWTWGWLL
                     GEVVRRVAGAPVSRVLADEVAGPLGVDRELFLAVPEADLARLARLEDAGLSALMTWAGA
                     NLPHFDAVAPPAVRPDTVIGSRPDVLRADVPSVGTMSARAVARMYAALLGPVDGVRLIS
                     AARMREVSAPAVRAQEWVFGQESTFGLGYAVEDDGSFGTAGSGGSLAFAYPDLGLTVAA
                     VRNRLGAGDGDPMEQLRALVRDRVAEATGHR"
     gene            complement(10001..11185)
                     /db_xref="GeneID:91355824"
                     /locus_tag="PVK74_RS06695"
                     /old_locus_tag="PVK74_06695"
     CDS             complement(10001..11185)
                     /codon_start=1
                     /db_xref="GeneID:91355824"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286437.1"
                     /locus_tag="PVK74_RS06695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06695"
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_338020355.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 8.6e-70, bitscore:
                     234.2, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQASSAVDVDLALVGGGGAASLVLAALDRHGVTGLRVAVVDPVHK
                     RGQDRTWAFWGLPGDDLDPLLSASWSQVDVVTRAGRRVLTLDPLRYAMLRSAPVYDRAA
                     AAERRLDAVRISAPAGELHDDGERVTVRDPERRELVRAGWVLDSRPRRPKRPGRTSWLQ
                     HFRGWWLAADRPTFDPQRAVLMDFRTPQPQRGVSFGYMLPVDDRFALVEYTEFGPALLD
                     DAGYDTALRGYADLLGLDLTALRVREVEDGVIPMTDGPFESRPSPRVVRLGTAGGATRP
                     STGFTFSAMLRQADQVARALAAGRPPVPAPAYPGRHLWMDAVALRALDRGHVGGVEFFE
                     RLFDRNPAERVLRFLDGVTSPAEDLAVMRSSPLLPMTGAVLGDAAGRLRARLRR"
     gene            complement(11234..12481)
                     /db_xref="GeneID:91355825"
                     /locus_tag="PVK74_RS06700"
                     /old_locus_tag="PVK74_06700"
     CDS             complement(11234..12481)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355825"
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286438.1"
                     /locus_tag="PVK74_RS06700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06700"
                     /product="MFS transporter"
                     /protein_id="WP_043323888.1"
                     /transl_table=11
                     /translation="MTGERLGGRFARLWTASTLSALGSGTATVAAPLYVASLTDDPLVV
                     SAGAAVSWLPWLLFALPGGVLADRVDRRRLMVLIDWVRVGALAVLAAAMLADRAGIALL
                     YAVLFVVNTGEVVFRTAAQAVLPAVVPRSLLERANGWLGGGTQVMQNMIAGPLGGFLFV
                     LAASLPFALNAGTYALSAVLVGLLAGTYRAGPAPDGRRSARAEVAEGFRWLWGQRLLRT
                     MTVLIGLLNVTLTAAVAVLVLLATERLGLGSVGYGALFTCMAVGGVLGSVVGDRLIAAI
                     TPTWTVRTGLLVEAGLHLALAASRSAAVVGFALFAFGAHSALWNIVANSLRQRLTPPAL
                     MGRVGSTTLFVAAGGNCVGALLGGVVAARFGITAPYWVGFVVAVAVIAATWRVFDRATV
                     AAAYAQPAPQEPAPVA"
     gene            complement(12524..13669)
                     /db_xref="GeneID:91355826"
                     /locus_tag="PVK74_RS06705"
                     /old_locus_tag="PVK74_06705"
     CDS             complement(12524..13669)
                     /codon_start=1
                     /db_xref="GeneID:91355826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013476711.1"
                     /locus_tag="PVK74_RS06705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06705"
                     /product="DUF6596 domain-containing protein"
                     /protein_id="WP_274479255.1"
                     /transl_table=11
                     /translation="MDEVALRSLIPGVLGVLVRRGADFAAAEDAVQDALIEALRVWPAD
                     PPRDPLGWLVTVAWRRFLDVVRADAARRRREDLVDEEPPPGPVPAVDDTLRLYFLCAHP
                     SLSPSSAVALTLRAVGGLTTRQIAQAYLVPEATMAQRISRAKRTVSGVRFDQPGDVATV
                     LRVLYLVFNEGYSGDVDLAAEAIRLTRQLAAAIDHPEVAGLLALMLLHHARRAGRTAPD
                     GSLVPLAEQDRSRWDTTLIAEGVGILQTALSRDRLGEFQAQAAIAALHADAPTAAETDW
                     VQIVEWYDELVRLTGNPIARLNRAVAVGEADGPRAGLAALAALDDTLPRYTAVAAYLHE
                     RDGDPDRAAGLYADAARRAASLAERDHLNRQAARLNSRRPG"
     gene            complement(13678..14085)
                     /db_xref="GeneID:91355827"
                     /locus_tag="PVK74_RS06710"
                     /old_locus_tag="PVK74_06710"
     CDS             complement(13678..14085)
                     /codon_start=1
                     /db_xref="GeneID:91355827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018784235.1"
                     /locus_tag="PVK74_RS06710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06710"
                     /product="YciI family protein"
                     /protein_id="WP_043323886.1"
                     /transl_table=11
                     /translation="MKYLLLKHYRGGPTPVTDMPMIDKWTPEEISAHVNYMQEFAARLQ
                     ESGEYVDGQALAPEGTFVRYDGEGRPPVTDGPFAETKDLIAGWMVIDVDSYERALELAA
                     ELSAAPGQGGKPIHEWLELRPFLTAPPTITE"
     gene            complement(14264..14680)
                     /db_xref="GeneID:91355828"
                     /locus_tag="PVK74_RS06715"
                     /old_locus_tag="PVK74_06715"
     CDS             complement(14264..14680)
                     /codon_start=1
                     /db_xref="GeneID:91355828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013476710.1"
                     /locus_tag="PVK74_RS06715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06715"
                     /product="DUF6069 family protein"
                     /protein_id="WP_274478511.1"
                     /transl_table=11
                     /translation="METTIPTAATRPTRRRVRLLTVLAATVATLLGWVVAVPLAGVELT
                     ARTGSDVQRVTPVAVAVSTLLAGLSGWALLALLERLTARARTVWTVVAGLVLLVSLLGP
                     LSGGVGGAATLTLVAFHLVAGTVLITGLRRGAAA"
     misc_feature    complement(14673..14688)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.35"
                     /tool="antismash"
     gene            14850..15953
                     /db_xref="GeneID:91355829"
                     /locus_tag="PVK74_RS06720"
                     /old_locus_tag="PVK74_06720"
     CDS             14850..15953
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355829"
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013476709.1"
                     /locus_tag="PVK74_RS06720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06720"
                     /product="histidine kinase"
                     /protein_id="WP_274478513.1"
                     /transl_table=11
                     /translation="MRCASRPRLLLLLDGGIATVSLAVCLLALLASDAGPDTTGATAVA
                     VGLAVAQAGCLLWIRRHPGYALGVAALAGVGLEALCPQLGWLGLVAVPMAYVARLRPPR
                     YSLVALGLLLAPTPWKLVTGGWRDLLLAVTALGLSWTLGELQRGQAQRRGERERQVRAA
                     ERERISRELHDVVAHHVAVIAVQAAAAEDVFDEQPEQARAALAAIDTAARSALTELRAM
                     LHALALDDGSEPDGPQPGLAQLDALADAVRAVGLRVTLRRDGDGEALPGGVQLSAYRIV
                     QESLTNALRHGHATRADVDVDYRDGVLRLEVVNDGPAPARRPGTTTGRGIVGMRERARL
                     LGGTLDAGPLPAGGFRVHARLPVEAAR"
     gene            15950..16618
                     /db_xref="GeneID:91355830"
                     /locus_tag="PVK74_RS06725"
                     /old_locus_tag="PVK74_06725"
     CDS             15950..16618
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355830"
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013476708.1"
                     /locus_tag="PVK74_RS06725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06725"
                     /product="response regulator transcription factor"
                     /protein_id="WP_069088645.1"
                     /transl_table=11
                     /translation="MTVRVVIADDQELIRAGLRTVLDARPDLSVVGEAADGVEAVAVAT
                     RTRPDVVLMDVRMPRRDGIAATRDLVAAGNPAKVVMLTTFDLDEHVYAALRAGASAFLL
                     KDTRPADLAEAVRVVARGEALLAPTVTRRLLDRYADRLPAPTPTGDALAVLTAREREVL
                     TLTARALSNAEIAARLHLSTATVKTHVSAILTKLGLRDRIQAVVLAYDTGLVRPEPPVR
                     "
     gene            16860..17342
                     /db_xref="GeneID:91355831"
                     /locus_tag="PVK74_RS06730"
                     /old_locus_tag="PVK74_06730"
     CDS             16860..17342
                     /codon_start=1
                     /db_xref="GeneID:91355831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286444.1"
                     /locus_tag="PVK74_RS06730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06730"
                     /product="hypothetical protein"
                     /protein_id="WP_043323881.1"
                     /transl_table=11
                     /translation="MKAQSFLGSAAFGVGLGALLLPAAALADTRVSPAATPVGGTVVLT
                     TTCNPNAGDAIFRVTGPDRDQNVRSTTAAAGGGLSAELFTAGFTLGTYTVATTCGDGSD
                     GGSATFTVTPIGGAQAGGGGRDGDTGVLVAGGVLAAGALAGGAYAVIRRRRAGAVA"
     gene            17416..18057
                     /db_xref="GeneID:91355832"
                     /locus_tag="PVK74_RS06735"
                     /old_locus_tag="PVK74_06735"
     CDS             17416..18057
                     /codon_start=1
                     /db_xref="GeneID:91355832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018784233.1"
                     /locus_tag="PVK74_RS06735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06735"
                     /product="class F sortase"
                     /protein_id="WP_069088694.1"
                     /transl_table=11
                     /translation="MLSESQRRSRLRTAVVVTAVTVAAATGTGLVSAGLGTTSTPPPQP
                     GVSAAPATERPGTAGPALPRATPVRVTIPRIGVDAEIVPVATDADGALEVPPLERPEVT
                     GWYHPGPAPGQAGNAVLVGHVDSQHGPAVFFDLGRLRPGDTIRVLRADGRTAAFTVDGV
                     GAYPKERFPTARVYGGDAAARLRLITCGGRFDPRTGSYPDNIVVFATATR"
     gene            complement(18061..19062)
                     /db_xref="GeneID:91355833"
                     /locus_tag="PVK74_RS06740"
                     /old_locus_tag="PVK74_06740"
     CDS             complement(18061..19062)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355833"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013476706.1"
                     /locus_tag="PVK74_RS06740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06740"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_274478516.1"
                     /sec_met_domain="APH (E-value: 2.1e-22, bitscore: 78.7,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVSPTQRVLDPDQVRRYLTASLGPGVEVADCGPLTGGGFAAVWQ
                     VRLTDGRDVVLKVGPPPHVPLLRYERDMVGAEAHYLRLVADHAPGVPTPALLHHGTDPE
                     LGDWLIMARLPGRTLWDLSQAGAEVGPLREEFGRALAALHAVTGERYGYDGDRAHGATW
                     RDAYTAMVDDMLADAADWAVPLPVPASRIRELVARHAAVLDAVRRPALLHFDGWAGNVL
                     AVDGPDGTPRLTGLVDGERYLWGDPLMDLVSPLLFRRAEDEPDDPLVRAYRAAAPFPLD
                     AGARRRLGLYRLYLYLLMTVEMPSRNITADNDPGRVALLAKLLDAELADLEG"
     misc_feature    complement(19021..19034)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            19173..19571
                     /db_xref="GeneID:91355834"
                     /locus_tag="PVK74_RS06745"
                     /old_locus_tag="PVK74_06745"
     CDS             19173..19571
                     /codon_start=1
                     /db_xref="GeneID:91355834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286448.1"
                     /locus_tag="PVK74_RS06745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06745"
                     /product="YchJ family metal-binding protein"
                     /protein_id="WP_274478518.1"
                     /transl_table=11
                     /translation="MARRGERTAACPCGTGRPYADCCAPVHRGEATAATAEALMRSRFS
                     AFALGDAAYLRHSWHSTTRPERLELDPGTRWTRLEIVETGQGGLFDSAGTVRFRAHYRE
                     GGRAGVLAEHSRFAREDGRWVYLDALPE"
     gene            complement(19669..20058)
                     /db_xref="GeneID:91355835"
                     /locus_tag="PVK74_RS06750"
                     /old_locus_tag="PVK74_06750"
     CDS             complement(19669..20058)
                     /codon_start=1
                     /db_xref="GeneID:91355835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286449.1"
                     /locus_tag="PVK74_RS06750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_06750"
                     /product="DUF2267 domain-containing protein"
                     /protein_id="WP_043323876.1"
                     /transl_table=11
                     /translation="MAEPEFYARVSARAGVPVETARALTEATLRTLAERISGGEADDLS
                     AHVAHELRPLLARARVEDPEVFGYDEFLRRVAERSGATPSDAERGARAVLQALHRVVGP
                     AQFNRALSQLPREIAELAQPAPRPA"
ORIGIN
        1 cccaccggca ccgcgggtgg aacgcgcacc ccgacggcag attgatcaag ctgggtgggt
       61 tgccggggat cggcaccagg tccgcgtccg cgtcaccgtg caacgacggc acactcgaca
      121 acaaccccca cgtgtacgga tgctgcggcg cccgcaacac ccgctccaca ctcccgtgct
      181 ccaccgcccg acccgcatac atcaccaaca cgtcatcagc cacctgcgac accacaccca
      241 ggtcatgcgt gatcagaatg atcgccgacc ggaactccgc ctgcagatcc gccagcaggt
      301 ccaggatctg cgcctgcacc gtcacatcaa gcgccgtcgt cggctcatcc gcgatcaaca
      361 gctccggatc attcaccagc gccatcgcga tcatcgcccg ctgccgcatc ccacccgaga
      421 actcatgcgg aaactgatcg aaccgcttcg ccggctgcgg aatccccacc cggcccagca
      481 tgtccaccgc ccgcgtccgg gcctcccgcc gcccggccct cggatgatgc acccgatacg
      541 cctccgcgat ctgccgcccc accgagtagt acggatgcaa cgccgacaac ggatcctgaa
      601 agatcatcgc catgtcccgg ccccgcaacc gacgaatctc ctcctcaccc agacccacca
      661 actgacgccc accgaccgag atctccccgg aaatggtcgt ccgcttcacg ttgtgcaagc
      721 cgaggatcgc cagcgacgtg acgctcttac cggaaccgga ctcgcccacg atccccagcg
      781 tgcgaccccg ctcgacagca aacgacaccc cgtccacggc ccgcaccaca ccgtcctcgg
      841 tgtcgaaccg cacccgcaga tccgtgaccc gcaggtacgg gtcctcgccg cgtcgcggcg
      901 tcggaagctc caccatgtcc gtctcctcct tcctcagccc agccggaccc gtgggtcgat
      961 caccgcgtac agcacgtcga cgacgatgtt ggcgaccacg atgaacacgg ccgccagcag
     1021 caccgtcgcc atcaccaccg gcaggttgag gaactgcacc gcctccactg tcgccttgcc
     1081 gaggccctgg aggccgaaga tggtctcggt gatgaacgtg ccgccgaggc tggtgccgat
     1141 gtccagcccg gcgatggtga cgatcggcgt gatcgccgcg cgcagcgcgt gccgggtgtg
     1201 cacctgccgc gcgggcagcc ctttcgcccg ggcggtgcgg atgaagtcct ccgacagggt
     1261 ctccagcatc tgcgcccggg acagccgggc gtacagcgcc gagttgagga aacccagcgt
     1321 catccagggc agcagcagcc cggccgccca ccgggccggg ctctcggtca gcggcgtgta
     1381 gctggggaac ggcagcagcc cggtggagta gacgagcagg tagagcagga tcagaccgaa
     1441 gaagtagacc tgcatggacg cgccggccag ggtgacgccg atggcggcgc ggtcgaacgc
     1501 cgtaccccgg cgcagcgccg acaccatgcc cagggagatg ccgaggccga gccagagcac
     1561 ggcgccgccg aggacgatgc tgaacgtcac cggggcgcgc tgcgcgacga tctcggtgac
     1621 cggctggttg ttgcggaacg agtaacccag gcagggcgcc gggcaatcct gccggaagtc
     1681 cccctcgccg taggtacggc cggcgaagac gccgccgacg aagtccgcgt actgccgggg
     1741 cagcggctgg tcgatgccaa ggcggcgctc gacctgggcg atgtcctcgg ccgtgcagtt
     1801 cttgccgcac atcaccttcg ccgggctgct cggcaccgcg aagaagagac cgaatgtgac
     1861 gaggctgatg acgaccaggg tcagggcggc gacgagcagc cgccggacga cgaaacggag
     1921 caacgggagc acctcccccg gggtggggcg cggggacgac cgccgtggca gccgtccccg
     1981 cgcggctgtc acttcttcac gtagatgccg ttgagcgaga tgatcccgaa cgcgtcgctg
     2041 aggaaggcgt tgccgacctt cgagccgtgc agctcgtagg tggcgtcgta gtagcagggc
     2101 accaccggcg cgtacttctc catgatcatg cggtcgagcg ccatccagcc ggcgtcctgc
     2161 tccgcggcgg gcagggcgcg gacccggtcg atctccgcgc cgaccgacgc ctcgttgagg
     2221 tacgacaggt tctggttgcc ctcggccacg atctcccgtc cgtcgtagac cggcgggatg
     2281 actgtggagc cggtgggcca gtccgagccc cagccggtga ggtagaggtc gtaggggttg
     2341 tccttgcggc ccacctcgtc gtagtagctg ctgttgtcga tcggcttcat gacgatgtcg
     2401 aaccccatgt cggtgaggtt cttgcgcagc gcctcggcct gctgggtacg cagttccagg
     2461 ctggagtggg cgagcaccag cttcggccgc tttccggcga gcaactcggc ggtcttcgcc
     2521 ttgtcgccgg tcaccggggc gttgaacacg tcgtacggca cgaacccggc ggtggtgggt
     2581 gacatcagcg tggtcgcggg tgtcccggcg gcctggccgc cgaggacctt gagcagggcg
     2641 tccttgtcga ccgcgtagtt cagcgcgcgc cgtacgttca ggtcggtgac ccgctgggtg
     2701 ttgatgctca gcacccagtt gtactgcgtc gggccgcgga cgacccggtc ggcgacgccg
     2761 gcgccggtgg tgcggggcag caccgacggc ggcacgtccg accagctcag cgccgcctgg
     2821 tcggccggtc cgtcggcgac cagccgctcg gcgatctggg cctgctccag gccgaacgtc
     2881 atccggaccg tgtccgggta cgcgttgcgg agcgggtcgg tcgccgggtc ccagttcggg
     2941 ttgcgttcca gctccagcga cacgtcgcgc tggtaggact tcacccggta cgggccggac
     3001 gagaacggcc gcagatcgta gttggcgcgg gtgtccttgg cggcgggcac cggcgcgctg
     3061 gtgggcagcg ccgccgcgta cggcatgtcg cagtgcggct gcgggaacgt gaaccggatg
     3121 gtccggtcgt cgggggtggt gacgccgtcg ggcaccggct tgccgccgtc gtacggtccc
     3181 ttgtaggtgg cgttgtacgc cccgcccggg tagagccact gctggatgta gtgcgggccc
     3241 tcgttgaggt tcgccgcgaa cgagcgggcg atgccgtggg cgacgtcctt gctgctcacc
     3301 ggcgtgccgt cctcgtagcg cacgccgtcg cgcagcgtga actcccagac cttgcagtcg
     3361 ccgtcgacgt ccttgccggg gttggtggcc aggtcgccga cgagcagcag cttgccggtg
     3421 ccgtcctcct tgtagccgtt gagcgggcgg tagagcatgc cgccggcgac ctgctgcacg
     3481 ttgacgtagt tgcgggccgg gtcgaggtgt tcgaagtcgg ccggctgcat gacggtgagg
     3541 gtgccgcccc gggacgcgcc gtcgactggc ttcgccgggc cctggttgtc ggcggcctcg
     3601 tacgagatcg agccgctctg ggtcttggtc ttctggtcgt cgccgccgct gtcgtcgggc
     3661 gtggggttgc agccggcggc ggccagcgcc gccgcggcga ggacacctgt cagtgtccgg
     3721 gttcgtgcgc gcacggtgtg ctcccttcgt gcccggcggc ccccgccggc cgggcgtgtg
     3781 atggccgtgg ggactaccgg gtggagcggg gatccagcga gtcgcgcagc gcgtcgccga
     3841 gcaggttgaa cgccaggacc agcaggaaga tcgtcaaccc ggggaacagg gtgtaccagg
     3901 ggtcgctcgc gacgtagccg atgctgttga agatcatgcg gcccaggtcg ggcgtgggtt
     3961 cggtgacgcc gatgttgacg aacgccagcg ccgcctcgat ggcgatgaac tggggcacca
     4021 tcagcgagac ggtgaccagg atcggcgccc agatgttcgg cagcagctgc cgcagcagga
     4081 tgtgcgcggt gccggcgccg gcggcccggg ccgcgtcgac gaactcccgc tcccgcagcg
     4141 agatcacctg cccgcggacc agccgcgcgg tgtacgtcca gctgaacagg ccgaaggtgg
     4201 cgacgatcag ggccacccgg aaggccggcg acggcgcctc ccggtcggag tagaagcggt
     4261 cctgcaggat cgggatgacc gcgagcgcga agatgaggaa cgggaacgcc agcgtgaggt
     4321 cgatcagcca gttgacgaga ctgtccagcc agcctctggc ccatccggcc agcacaccga
     4381 ccgcgacgcc gatgcacgag gccagcagcg ccgaggtgaa cgcgatgaac agcgacgtcc
     4441 gaaggccgta gaccagttgc atcaggatgt cccggccact gcccggctca aggcccagcc
     4501 aatgatcgga actgatcccg ccggcatacc cgatcggcat tccgaaatcg ttcaaccggt
     4561 cgacgaactt gtcggtcggg tcgattccgg tgagccgccc cagcagcggc gcgccgagcg
     4621 ccaccaccgc ggccacgagg agcgtcaggg cgctgacccg ggccgttcgg tcccgcttga
     4681 gccgcagcca ggcgagctgg ttcggtgacc ggccgacgaa ctcggcggtc cggccgacgg
     4741 gttcggagtc ggcctggatc tcggggccgg gaatggtcgc ttcggcggcc gtggtccggg
     4801 gcggcgggtg tgagagatcg ctcatgaaca gtccctccga cgggggcgaa aacgccctgc
     4861 cacccgacgg taaagggata cggagcaccg gaaagaatcg ttacggtaac ggccgttccg
     4921 gttgtcatcc attgacaacg atccggcgta cggaatgcat cggcgcaata acgggccgat
     4981 ttggttgtca gcctttcagg caggcgtcac gcttattcgg aatgcgttta cgcgaggcgc
     5041 ggaagcggtt gtcagccgtt cgggcattcc cgtacgccga tgtcacaccg aacgtgcgac
     5101 gcggtcggct ggtgtaacac ttcgtgactc ttcgcgttca caccgtccac ctagggttct
     5161 cggcggcccg gttcgcacga cggaccgggt cacccatcgg ccccgcaccc cggggccccg
     5221 acggaaggac cacccatgcc cttcgcccga cgtaccgccg cactggccct ggtcgccgcg
     5281 ctcggcgcgc cggcctcccc cgcgcaggcc gcgccgcgcc ccggcccgca gaccccctcg
     5341 gtgctgctgc tcaccgtcga cgacggcgcc ggcgtacacg ccacggtgct gacctgcggg
     5401 ccgaccggcg gtctgcaccc cgacccgttc accgcctgcc ggctcgtcgc ccgcgtcgac
     5461 ggcgacctgg acgcgctcga cgtggacggc gcgccgtgca cctcccagta cgccccggtc
     5521 gtcgcccgcg ccgcaggctt ctggcaggcc cgcccggtct cctacacgcg cacgttcgcc
     5581 aacccctgcc tgatgcagcg caccaccgcc tccctcttca ccttctgacc ctcccctctc
     5641 gttctggttg atcatgaggt tggcggcggt tgccgtccgt tttgtcgccg tcaacctcat
     5701 gatcgacggg gtgggtgggg tgggggtggg gtgggtgcgg agaatggtgc gggtggacgg
     5761 gggtgctgtg gaggcgcgca cggtcggtgg cgggcgggag ctgcgggcgg actgttcgcg
     5821 ctgcgccggg gtctgctgcg tcgcgccggc gttcaccgcg tccgccgact tcgccatcga
     5881 caagcccgcc ggacggccct gcccgaacct gggcgccgac ttccgctgcg gcatccacac
     5941 cgagctgcgg caacgcggct tccccggatg caccgtgttc gactgcttcg gtgccggcca
     6001 gcacctcacc cggcacacgt tcgccggccg cgactggcgc gccgacccgg ccaccgcagc
     6061 gcggatgttc gacaccttcg cggtgttgcg gcccctgcac gagttgctct ggtacctgac
     6121 cgaggcggta cgcctgaccc cgcccggccc gctgcgcgac gagctgacgg cagtgctgga
     6181 cgagaccggc cggctcgccg acggcacccc tgacgagctg ctcgcactcg acgtcgacgc
     6241 gcatcgggac cgggccaacc ggctcctgtc ccgcgccgcc gaacaggccc gcgccgggcg
     6301 ggccggcccg gaccgccggg gcgcgacgct gatcgctgtg gacctgcgcc gtacgccact
     6361 ggccggggcc aacctgcgcg gcgcctgcct gatcggcgcg gacctgcggg gcgtacggct
     6421 cggcgcggcc gacctgaccg gcgcggacct gcgcggggcc gacctgcgcg gcgccgacct
     6481 gagcgagtgc ctgttcacgc accagtcgca gctcgacgcc gcgcgcggcg accaccgcac
     6541 ggtcctgccg ccggggctgc gccgcccggc ccactggtcc ctgacgctga ccccggcccg
     6601 cccccggcca cgcccccgcc gccgctgacc cgcccggccc gccggtccgg acactgggcg
     6661 acgatcaagg agtttgtggc tggttcgggg ccggatcggg acacaaactc cttgatcaac
     6721 ggggagaagg ggggccggag ggcggagggg gcggggtttg gtggggatgg ggtggggtag
     6781 gcggcgcgga cgactgttgg tcgacgggag gggcaccggt gggatatcgg gcacgcgacg
     6841 gtgaggagcc ggtcgatccg gcgcacgccg aggacgaggc cgggcaggtt ccgctggtgc
     6901 agacggccgc ggacaccgac gtgccggcgc ccgcacccgg cgcgccgaaa ccggacgagg
     6961 tgaccgagga cgacggctcc ggcatggcgg gcggcgcctc cggcagcagc tcgggcggct
     7021 cctcgatgcc gacccacccg gacgcggccc gcggacggga cgccgccggc tgagcaggcg
     7081 cgagcaccgg ccggacacca ggccacccga acgtttgccg tcacccgctg cgggcaggag
     7141 tgcgacatga ccagtgaaga gtccttcggc cgcgcggccg gcgacgaacc cgacggcgtg
     7201 accgcgtacg aggcgtccct gcgcccgccg ggcgagtccc tgcacaccac cgacgacacc
     7261 ggtgacgact tcgccgacct gcccgccgag gaccgccggt ccgcgcggga ggtcagccgc
     7321 gccggctacg acgtcgacgc ggtctccggg accggcgacc cgtccgagga gccggaggag
     7381 atcgaggagg gccggccgct gcgctgacgc gtgcgcgggg cggcggccgt gccgctccgc
     7441 gcctcggtca tgccccggtt cgccagcgcg tcggcgcgtt cgttctccgg gtgcccgttg
     7501 tggcccttca cccacagcca cgtcacgtcg tgccgggcac aggccgcctc cagcgcctgc
     7561 cacaggtcgg cgttcttcac cggctgcttc gcggcggtca gccagccgtt gcgcttccag
     7621 gcgttcagcc agccggtgat gccgttgcgt acataggtgc tgtcggtgtg cagccgtacc
     7681 gtgaccgggc gggtcaggct ctccagcgcc cggatcgcgg cggtcagctc catccggttg
     7741 ttggtggtcg gggtggcctc gccgccgcac agctcccgct cgtgcccgcc ccagcgcagc
     7801 accgcgcccc acccgccggg cccgggattg ccgctgcacg cgccgtcggt ccagatctcc
     7861 acgacccggc cggtctccgc ctccgccatg cccggcaacc taccgggtac gcgagcacgc
     7921 gggaccaccc gacccgccgc gcgcggttac cgtgccggca tgaccactcc cccggacttc
     7981 gccaccctct gcaacttccg ggacctcggc ggctggcgga ccggcgacgg ccgcaccgtc
     8041 gcccggggcc gcctctaccg ctccgactcg ctggccaagc tcgccggtga cgacctgcaa
     8101 cggttcgcgg cgctcggcgt ccgcaccgtg atcgacctgc ggtatccgtg ggagatcgcc
     8161 gaccgcggcc gggccccgga gagcctcggc gtgacctggc acaacctgag catcgagcac
     8221 cggccgtacg tgcaggccga catcgatccc gacgtggacc cgtggcgcta cctggccgac
     8281 cggtacgccg aggtggccga ggacggcgtg gccgagctgc gccgggcggt cgaggtgatc
     8341 gcggacggcg agcatccgct ggtgttccac tgcgcgtccg gcaaggaccg taccggcctg
     8401 ctcgccgcgc tggtgctgtc cctgctgggg gtggacgacg accagatcgc cgcggacttc
     8461 gcgctcaccg agcacgccac cgaccggctg gtcgccgagt ggcgggaccg caacggcggc
     8521 gcgacgccgg gctggcccgc gtacgggcgg gcgccggccg aggtcatccg gctggtgctg
     8581 gccgacctgc gggccgcaca cggttccgtg cacgggtacg tgaccggccg gctcggtgtc
     8641 gacgcgcaga cgatcgacgc gctgcgggcc cggctgctca ccggcgacac ggacccgctg
     8701 ccgacccagg gcgccaccgg cgccacgccg acgacactcg cccgctgagc gccgccgccc
     8761 ggccgagcac gcagcgacgg agaaccggcg gccgaaaagc gagcgacggc ggcgcggcgg
     8821 tctggcacgc tgcgagatcg tggacacgcg gtgggacggc ctgcgggccg aggtacggga
     8881 cacgatcgac gagctggtct cctccggctg ggaggccggt gtgcaggtgg ccgcgtacct
     8941 ggacggggtg gcgatcgtct ccgaacacgc ggggctcgcc gacaccacca ccggacggcc
     9001 gatgaccgcc gacacgcctg tgcacgcggt ctccaccggc aagggactca ccgccaccgt
     9061 cgtgcacgtg ctcgccgagc ggggacggct cgactacgac ctgccgcttg ccgcggtgtg
     9121 gccggagttc gcccggcacg gcaaggacgc catcacgctg cggcacgtgc tcacccacac
     9181 cgccggcctg cccgcgctgc ccgccggcgt cacgccggag gacttcaccg actggacgcg
     9241 catgtgcgag ctgctggcag acgcgcggcc gctgtgggcg cccggcgagc ggctggcgta
     9301 ccacgcctgg acgtgggggt ggctgctcgg cgaggtggtc cggcgggtcg ccggcgcgcc
     9361 ggtgtcgcgc gtgctcgccg acgaggtggc cgggccgctc ggcgtggacc gggaactgtt
     9421 cctcgccgta ccggaggcgg acctggcccg gctggcccgg ctggaggacg ccggcctgtc
     9481 cgcgctgatg acgtgggccg gggcgaacct gccgcacttc gacgcggtcg ccccgccagc
     9541 ggtacgcccc gacaccgtca tcggttcccg ccccgacgtg ctgcgcgccg acgtgccgtc
     9601 ggtcggcacg atgagcgccc gcgcggtggc ccggatgtac gcggcgctgc tcggcccggt
     9661 cgacggggta cggctgatct ccgccgcgcg gatgcgggag gtgtccgccc cggcggtacg
     9721 cgcccaggag tgggtgttcg gccaggagag cacgttcggg ctcgggtacg cggtcgagga
     9781 cgacggatcg ttcggcaccg ccggtagcgg tggcagcctc gcgttcgcgt acccggatct
     9841 ggggttgacg gtggcggcgg tgcgcaaccg gctcggcgcg ggcgacggcg acccgatgga
     9901 gcagctgcgg gcgctggtgc gcgaccgcgt cgccgaggcg accggccacc ggtagcgccg
     9961 agaaggcaga cgccggccac gacccggaca ggcgagcaga ctagcggcgc aggcgggccc
    10021 gcagccggcc ggccgcgtcg ccgagcaccg cgccggtcat cggcagcagc gggctggacc
    10081 gcatcaccgc caggtcctcg gccgggctgg tcacgccgtc gaggaaccgc agcacccgct
    10141 ccgccgggtt gcggtcgaac agccgctcga agaactccac cccgccgacg tgcccccggt
    10201 ccagcgcgcg cagcgccacc gcgtccatcc acaggtgccg ccccgggtac gcgggcgcgg
    10261 gcaccggcgg acggccggcg gcgagcgccc gggccacctg gtcggcctgg cgcagcatcg
    10321 cggagaacgt gaagccggtg gacgggcggg tcgccccacc ggcggtgccc agccgcacca
    10381 cgcgtgggct cgggcgggac tcgaacgggc cgtcggtcat cgggatcacg ccgtcctcga
    10441 cctcccgcac ccgcagcgcg gtcaggtcca gcccgagcag gtcggcgtag ccgcgcagcg
    10501 ccgtgtcgta gcccgcgtcg tcgagcaggg ccgggccgaa ctcggtgtac tcgaccagcg
    10561 cgaaccggtc gtcgacaggc agcatgtacc cgaaggagac gccgcgctgc ggctgtgggg
    10621 tgcggaagtc catcagaacg gcccgctgcg gatcgaacgt cggtcggtcg gcggccagcc
    10681 accagccccg gaagtgctgc aaccagctgg tccgccccgg tcgtttcggc cgccggggcc
    10741 gcgagtcgag cacccagccg gcccgcacca gctcacgcct ctcggggtcg cggacagtga
    10801 cccgctcacc gtcgtcgtgc agctcccccg ccggagcgct gatccggacc gcgtccagcc
    10861 gccgctcggc cgcggcagcc cggtcgtaga ccggggcgga gcgcagcatg gcgtaccgca
    10921 gcgggtcgag cgtgaggacg cggcggccgg cgcgcgtgac cacgtcgacc tgcgaccagc
    10981 tcgcgctcag cagcgggtcg aggtcgtcgc cgggcaggcc ccagaacgcc cacgtgcggt
    11041 cctggccgcg tttgtgcacc gggtcgacca ccgcgacccg cagcccggtc acgccgtggc
    11101 ggtccagcgc ggccaggacc agggacgcgg cgccgccgcc gccgaccagc gcgaggtcga
    11161 cgtcgaccgc tgaggatgcc tgcacccgac cacgctgtca catcggcggg cgcggccctc
    11221 ggccgacccg cgctcaggcc accggggcgg gctcctgcgg ggccggctgg gcgtaggcgg
    11281 cggccaccgt cgcccggtcg aagacccgcc acgtcgcggc gatcaccgcg accgccacca
    11341 cgaaacccac ccagtacggc gcggtgatgc cgaaccgggc cgccaccaca ccgcccagca
    11401 gcgcgccgac gcagtttccg cccgccgcga cgaacaacgt ggtgctgccg acccggccca
    11461 tcaacgcggg cggcgtgagc cgctgccgca gcgagttcgc cacgatgttc cacagcgcgc
    11521 tgtgcgcccc gaacgcgaac agcgcgaacc cgaccacggc ggcgctgcgg gacgcggcca
    11581 gcgccaggtg cagtcccgcc tcgaccagca gcccggtccg caccgtccag gtgggcgtga
    11641 tcgcggcgat cagccggtcc cccaccaccg agccgagcac gccgcccact gccatgcagg
    11701 tgaacaacgc gccgtagccg accgagccga gacccagccg ttcggtggcg agcagcacca
    11761 gcaccgccac ggcggcggtg agcgtgacgt tgagcaggcc gatcagcacg gtcatggtgc
    11821 gcagcagccg ctgcccccac aaccagcgga acccctccgc gacctccgcc cgcgccgaac
    11881 gccgcccgtc cggcgccggc ccggcacggt acgtcccggc gagcagcccg accagcacgg
    11941 cgctgagcgc gtacgtgccg gcgttcaggg cgaacggcag cgacgccgcc agcacgaaca
    12001 ggaacccgcc gagcgggccg gcgatcatgt tctgcatcac ctgggtgccg ccgcccagcc
    12061 acccgttggc gcgttccagc agcgagcgcg gcaccaccgc aggcagcacc gcctgcgcgg
    12121 cggtacggaa caccacctcg ccggtgttca ccacgaacag caccgcgtac agcagcgcga
    12181 tcccggcccg gtcggcgagc atcgccgccg cgagcacggc gagcgcgccg acgcgtaccc
    12241 agtcgatgag caccatcagc cgccgccggt ccacccggtc ggccagcacg ccgccgggca
    12301 gcgcgaacag cagccacggc agccacgaca ccgccgcccc ggccgacacc accagcggat
    12361 cgtcggtgag cgacgccacg tacagcggcg cggccacagt cgccgtcccg ctgcccagcg
    12421 cggacagcgt gctcgccgtc cacagtcggg cgaagcgccc gccgagccgt tcccccgtca
    12481 cggcgaggca acctaccagc ggcgacgaag cctgccgacc ggtttatccg gggcggcggg
    12541 agttgaggcg ggccgcctgc cggttgaggt ggtcgcgttc ggccaggctg gccgcgcgac
    12601 gggccgcgtc ggcgtacagg ccggctgccc ggtccgggtc gccgtcgcgt tcgtgcaggt
    12661 acgcggccac cgccgtgtac cggggcaatg tgtcgtcaag cgccgcgagc gccgccagcc
    12721 cggcgcgcgg gccgtccgcc tcgccgaccg cgaccgcccg gttgagccgg gcgatcgggt
    12781 tgccggtcag gcggaccagc tcgtcgtacc actcgacgat ctgcacccag tcggtctccg
    12841 cggcggtggg cgcgtccgcg tgcagtgccg cgatcgccgc ctgggcctgg aactcgccga
    12901 gccggtcgcg ggacagcgcg gtctgcagga tgcccacgcc ctcggcgatc agcgtggtgt
    12961 cccaccggct gcggtcctgc tcggccagcg gcaccaggct gccgtcgggc gcggtccggc
    13021 cggcccggcg ggcgtggtgc agcagcatga gcgcgagcag cccggccacc tcggggtggt
    13081 cgatcgcggc ggcgagctgc cgggtgagcc ggatcgcctc ggcggccagg tccacgtcgc
    13141 cggagtagcc ctcgttgaac accaggtaca gcacgcgcag cacggtggcg acgtcaccgg
    13201 gctggtcgaa gcggaccccg gagacggtgc gcttggcccg gctgatccgc tgcgccatgg
    13261 tggcctccgg caccaggtac gcctgcgcga tctgccgggt ggtgagcccg ccgacggcgc
    13321 gcagcgtcaa cgcgacggcc gacgacgggc tcagcgacgg atgcgcgcag aggaagtaga
    13381 gccgcagcgt gtcgtccacc gccggcaccg gcccgggcgg cggctcctcg tccacgagat
    13441 cctcacgccg gcgccgggcg gcgtcggcgc ggaccacgtc caggaaccgg cgccacgcca
    13501 cggtcaccaa ccagcccaac gggtcgcggg gcgggtcggc cggccagaca cgcaacgcct
    13561 cgatcagcgc gtcctgcacc gcgtcctcgg ccgccgcgaa gtcggctccg cggcggacga
    13621 ggacaccgag cacgcccggg atgaggctgc ggagcgcgac ctcgtccatc ggacggatca
    13681 ctcggtgatg gtcggcggcg cggtcaggaa cgggcgcagc tccagccact cgtggatcgg
    13741 cttgccgccc tgccccggcg cggccgacag ctcggcggcc agttcgagcg cgcgctcgta
    13801 gctgtccacg tcgatcacca tccagccggc gatcaggtcc ttcgtctcgg cgaacgggcc
    13861 gtcggtgacc ggcgggcgtc cctcgccgtc gtagcggacg aacgtgccct ccggggcgag
    13921 cgcctggccg tcgacgtact cgccgctctc ctgcagccgg gccgcgaact cctgcatgta
    13981 gttcacgtgc gcggagatct cctccggcgt ccacttgtcg atcatcggca tgtcggtgac
    14041 cggggtcggg ccgccgcggt agtgcttcag gagcaggtac ttcatctgtg tctcctcgtg
    14101 gagggtgcga cccattctgg ccgcgttcac tccggggacg aagccgcctg cccgttctcg
    14161 acatcggtgg cggcggaatt tccggcgtca catcgcgtag ggcatcctag gaggctagtt
    14221 ctggaggccg ggccgcctgc ccccgtcgcg gcggcccggc ccgtcaggcg gcggcgccgc
    14281 ggcgcagacc ggtgatcagc accgtgcccg cgaccaggtg aaacgccacc agtgtcagcg
    14341 tcgccgcgcc ccccactccc ccgcttagcg gaccgagcag cgacaccagc agcaccaggc
    14401 ccgcgaccac cgtccagacg gtccgggcgc gggcggtgag ccgctccagc agggccagca
    14461 gcgcccagcc ggacagcccg gcgagcagcg tgctcaccgc caccgccacc ggcgtcaccc
    14521 gctgcacgtc cgaaccggtg cgcgcggtca gctccacccc ggccagcggc accgcgacca
    14581 cccagcccag cagcgtggcc acggtggcgg cgagcaccgt cagcagccgc acccggcggc
    14641 gggtcgggcg ggtggcggcg gtcggaatcg tggtttccat cggtagctcc tcggcatcgg
    14701 gacgactgcc gccgacgcta ggtccggcgg gccgccgcgc ggatcgggcc gcggagcggt
    14761 tcccggctcc gtcgccggac cgatcaccgg cccggatctc cgtctggcga ccgatgagaa
    14821 gcggtgcgca cgcggcctag catccgggca tgaggtgcgc gtcccggccc cggctcctgc
    14881 tgctgctcga cggcggcatc gccaccgtga gcctcgccgt gtgcctgctc gcgctgctgg
    14941 cctccgacgc cggcccggac acgaccggcg cgaccgccgt cgcggtcggc ctcgccgtcg
    15001 cgcaggccgg ctgtctgctg tggatccggc gccacccggg gtacgccctc ggcgtcgccg
    15061 cgctcgccgg cgtcggcctc gaggcgctct gcccgcagct cggctggctc ggcctggtcg
    15121 cggtgccgat ggcgtacgtg gcccggctgc gcccgccccg gtactcgctc gtcgcgctcg
    15181 ggctgctgct cgcgcccacg ccgtggaagc tggtcaccgg cggctggcgg gacctgctgc
    15241 tggcggtgac cgcgctgggc ctgagctgga cgctcggcga actgcaacgg ggccaggcgc
    15301 aacggcgcgg cgagcgcgaa cggcaggtac gcgccgccga acgggagcgg atctcccggg
    15361 agctgcacga cgtggtggcg caccacgtcg cggtcatcgc ggtgcaggcc gccgccgccg
    15421 aggacgtgtt cgacgagcag ccggagcagg cccgcgccgc gctcgccgcg atcgacacgg
    15481 cggcccggtc ggcgctgacc gaactgcggg ccatgctgca cgcgctcgcc ctcgacgacg
    15541 ggtccgaacc ggacggaccg cagccgggac tggcgcagct cgacgcgctc gccgacgcgg
    15601 tacgggcggt gggcctgcgg gtgacgctgc ggcgcgacgg cgacggcgag gcgctgcccg
    15661 gcggggtgca gctgtcggcg taccggatcg tgcaggagtc gctgacgaac gcgctgcgcc
    15721 acgggcatgc cacccgcgcc gacgtggacg tcgattaccg cgacggcgta ctgcggctgg
    15781 aggtcgtcaa cgacggcccg gcgcccgccc gccgccccgg cacgaccacc gggcgcggca
    15841 tcgtcggcat gcgggaacgg gcccggctgc tcggcggcac actggacgcc ggcccgctgc
    15901 cggccggcgg attccgggtc cacgcccggc tgccggtgga ggcggcccga tgacggtacg
    15961 ggtggtcatc gccgacgacc aggagctgat ccgcgccggg ctgcgcacag tcctcgacgc
    16021 gcggcccgac ctgagcgtgg tcggcgaggc cgccgacggc gtcgaggcgg tcgcggtggc
    16081 gacgcgtacg cggccggacg tggtgctgat ggacgtgcgg atgccccgcc gcgacggcat
    16141 cgccgccacc cgcgacctgg tggccgccgg caacccggcc aaggtggtca tgctgaccac
    16201 gttcgacctg gacgaacacg tctacgccgc gctgcgcgcc ggggccagcg cgttcctgct
    16261 caaggacacc cgcccggccg acctcgccga ggcggtacgc gtggtggccc ggggcgaggc
    16321 gctgctcgcg ccgacggtga cccggcggct gctggaccgg tacgccgacc ggctgcccgc
    16381 gcccacgccc accggtgacg ccctcgccgt gctgaccgcc cgcgaacggg aggtgctgac
    16441 gctcaccgcg cgggcactgt ccaatgcgga gatcgccgcc cggctgcacc tgagcaccgc
    16501 caccgtgaag acacacgtct cggcgatcct caccaagctg ggcctgcgcg accggatcca
    16561 ggcggtggtg ctcgcgtacg acaccgggct ggtccggccg gaaccgcccg tccggtaggc
    16621 gcgaaacgga cagcggaccc agacacggcg aagcgggacg gctcgccgtc cggcctggcc
    16681 cggcatgtcc accctccgac ggcggcaggg agcacaccgg acggcaacga agatttctca
    16741 attaccccca gtgaccgccg caaccctcct agtgttggcc acaccggtgc tcgtcacgga
    16801 gttggccacc cgaacgacgt cccacgccta cagcggacga aaagtgaggg aagacgcgga
    16861 tgaaggcaca gtcatttctc ggatcggcgg cgttcggcgt gggcctcggc gcactgctgc
    16921 tcccggccgc cgcgctggcg gacaccagag tctcacccgc cgccacaccg gtcggcggca
    16981 ccgtcgtgct gaccaccacg tgcaacccga acgccggtga cgcgatcttc cgggtcaccg
    17041 gcccggaccg ggaccagaac gtccggtcca ccactgcggc cgcgggcggt ggcctgagcg
    17101 ccgaactgtt caccgccgga ttcacgctcg gcacgtacac cgtcgccacc acgtgcggcg
    17161 acggcagcga cggcggcagc gccacgttca ccgtcacccc gatcggcggc gcgcaggccg
    17221 gtggcggcgg gcgcgacggc gacaccgggg tgctggtcgc cgggggcgtg ctggccgccg
    17281 gggcgctcgc cggtggcgcg tacgcggtca tccgccgacg ccgcgcgggc gccgtcgcct
    17341 gaccggatcg tcgagcggtc cgcccgcgcc ggagcacccg gcgcgggcgg cacgtccctg
    17401 tcggacggag gtgggatgct gtcggagtcg cagcgccggt cgcggctgcg caccgccgtc
    17461 gtggtcaccg ccgtcaccgt cgccgccgcc accggcaccg gactggtctc ggccgggctc
    17521 ggcaccacgt cgacgccacc gccacagccc ggcgtctccg ccgcgcccgc caccgaacga
    17581 ccgggtacgg caggcccggc gctcccccgc gccacaccgg tgcgggtgac catcccgcgc
    17641 atcggcgtgg acgccgagat cgtgccggtg gccaccgacg ccgacggcgc gctggaggtc
    17701 ccgccgctgg aacgcccgga ggtcaccggc tggtaccacc ccggtcccgc ccccggccag
    17761 gccggcaacg cggtgctggt cgggcacgtc gactcgcagc acggcccggc ggtcttcttc
    17821 gacctcggcc ggctgcgccc cggcgacacg atccgggtgc tgcgcgccga cggccggacc
    17881 gcggcgttca ccgtggacgg cgtcggggcg tacccgaagg aacgcttccc caccgcgcgg
    17941 gtctacggcg gcgacgctgc tgcgcggctg cgtttgatca cgtgcggcgg gcggttcgac
    18001 ccgcggaccg gcagctaccc ggacaacatc gtggtcttcg ccaccgctac ccgctgacgc
    18061 tcagccttcc aggtcggcca gttccgcgtc gagcagcttc gccagcagcg ccacccggcc
    18121 cgggtcgttg tcggcggtga tgttccggct gggcatctcg acggtcatca gcaggtagag
    18181 gtacagccgg tacaacccga gccgccgccg cgccccggcg tcgagcggga acggcgccgc
    18241 cgcccggtag gcgcgcacca gcgggtcgtc cggctcgtcc tcggcgcggc ggaacagcag
    18301 cggcgacacc aggtccatca gcggatcgcc ccacaggtag cgttcgccgt cgaccaggcc
    18361 ggtgagccgg ggcgtgccgt ccggcccgtc cacggcgagc acgttgccgg cccagccgtc
    18421 gaagtgcagc agcgccggac ggcgtaccgc gtcgagcacc gccgcgtgcc gcgccaccag
    18481 ctcccggatc cgggacgccg gcaccggcag cggcaccgcc cagtcggcgg cgtcggcgag
    18541 catgtcgtcc accatcgccg tgtacgcgtc ccgccaggta gccccgtgcg cccggtcgcc
    18601 gtcgtagccg taccgctcgc cggtgacggc gtgcagcgcg gcgagcgcgc ggccgaactc
    18661 ctcgcgcagc ggcccgacct ccgcgccggc ctggctcagg tcccagaggg tacgacctgg
    18721 tagccgcgcc atgatcagcc agtcgcccag ctcggggtcg gttccgtggt gcagcagcgc
    18781 cggcgtcggc acccccggtg cgtggtcggc gaccaggcgc aggtagtgcg cctccgcgcc
    18841 gaccatgtcc cgctcgtagc gcagcagcgg cacgtgcggc ggcggaccga ccttgagcac
    18901 cacgtcccgg ccgtcggtga ggcgtacctg ccagacggcg gcgaagccgc caccggtcag
    18961 cgggccgcag tcggccacct cgacgccggg cccgagcgag gcggtgaggt atcggcggac
    19021 ctgatcgggg tcgaggacac gctgagtcgg actcacgctc atggtccggg aagcctactg
    19081 ggttgaggtg taaggagggg ccccctgtta acgcctccgg tagaggaagg gccccttgtt
    19141 aacacctctc cgaggcttgg gagaatcgcg gcatggcgag acggggtgaa cggacggcgg
    19201 catgcccgtg cggcaccggc cggccgtacg cggactgctg cgccccggtc caccggggcg
    19261 aggcgacggc ggcgaccgcg gaggcgctga tgcggtcccg gttcagcgcg ttcgcgctcg
    19321 gcgacgccgc ctacctgcgg cacagctggc actcgaccac ccggcccgag cggctggagc
    19381 tggacccggg cacccgctgg acccggctgg agatcgtgga gaccgggcag ggcggcctgt
    19441 tcgacagcgc cggcacggtc cggttccggg cgcactaccg cgagggtggc cgggcgggtg
    19501 tgctggccga gcacagccgc ttcgcccgcg aggacggccg ctgggtctac ctggacgcgc
    19561 tgcccgagtg acgcctcccc ggcaccgacg cgcgcagcct gcggcggcgg gtgttaacaa
    19621 ggggcccttc ctctaccgga ggcgttaaca aggggccctt cctttcgcct aggccgggcg
    19681 cggggcgggc tgggccagct cggcgatctc gcgcggcagc tgggacagcg cccggttgaa
    19741 ctgggccggc ccgaccaccc ggtgcagcgc ctgcagcacc gcccgcgcgc cgcgctcggc
    19801 gtcggacggg gtcgcgccgg agcgctcggc gacccggcgc aggaactcgt cgtacccgaa
    19861 gacctccggg tcctcgaccc gggcgcgtgc cagcagcgga cgcagctcgt gcgcgacgtg
    19921 cgcggacagg tcgtcggcct cgccgccgct gatccgttcg gcgagcgtgc gcagcgtcgc
    19981 ctcggtcagc gcgcgggccg tctcgaccgg tacgccggcg cgggcggaca cccgcgcgta
    20041 gaactccggt tcggccatcg tctgtcctcc cgtcgcaacg gcagcgtggc tacccgccgc
    20101 cggcttcggc aaacaccgcc gctgacctgg ccccggcgac caggcgttca ggccagggcc
    20161 cgcgccgccg agacgatcgc gccgacgccg atgccggccc ggtcgaactg ctgggcgggg
    20221 gtgccggagc cgggcagccc gcgtaccgcc aggtggttga cccgggacgg ttcgcccagg
    20281 tcggcgagcg cctccagcac cgctgagccc agcccgccct ccgggtagtg gtcctcgacc
    20341 accaccagcc gcccgccggt ctccaccacg gtctcggcga ggcgctgccg gtccaccggc
    20401 ttgatcgagt acatgtcgat cacgcgcgcg tcgatgccct cgcgggtcag ttcgtcggcg
    20461 gcggtgaggc agaggtgcac cgtcacgccg gtgccgagca gcgccacgtc gccgccgtcg
    20521 cgcaccattc ggctgccgcc gatcgggaac ggctcgccgt cgtcgtagag caccgggtac
    20581 ttgccgcgcg tggtgcgcag gtaggtgatg cccgggtggt cggccatctg ggcgaccagc
    20641 gccgcgcagg agaccgcgtc ggccgggctg agcaccgtgg agccgggcac cgcgcgaagc
    20701 gccgcgatgt cctccagccc catctgggac gggccgtccg ggccgatctc gaccccggcg
    20761 tgcgagccga ccagcgcgat gtcggcccgg gacaccccgg ccatccggat gaagtcgtac
    20821 gcccgggacc agaacgcggc gaaggtcgcc gcgaacggcc ggtagccgcg taccgccagg
    20881 cccaccgccg cggcggcgag ctgctgctcg gcgatgaaca tctggaagaa ccgatcgggg
    20941 tacgcggcgg cgaagctctc cgcccgggtg gagtcgctga cctctccgtc gagcgcgacc
    21001 acgtcgggcc gggcggcgcc gagggcgcgc agcgcgtcgc cgtacgcgtt ccgggtggcc
    21061 accttcgtcc cgcgctcgta ccggggcagc tccggctgcc ggtgctcggc ggcggcggtg
    21121 cgcggcgcgg cgggaggttt cggcccggcg acccggatcc ggcgggggcc gccgagcgcc
    21181 cgtac
//
