LOCUS       NZ_CP118233            21905 bp    DNA     circular CON 13-JUL-2024
DEFINITION  Micromonospora chalcea strain 1K05785M01 chromosome, complete
            genome.
ACCESSION   NZ_CP118233
VERSION     NZ_CP118233.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora chalcea
  ORGANISM  Micromonospora chalcea
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Study on the Growth Characteristics and Drug Resistance Related
            Proteins of Micromonospora chalcea MCCC 1K05785
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2023) Tianjin University, Tianjin University,
            Weijinlu Nub92, Tianjin, Tianjin 300072, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2022
            Assembly Method                   :: CLC NGS Cell v. 5.29
            Assembly Name                     :: TJU-micro-1.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028768405.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 23:01:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,224
            CDSs (total)                      :: 6,161
            Genes (coding)                    :: 6,110
            CDSs (with protein)               :: 6,110
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 51
            CDSs (without protein)            :: 51
            Pseudo Genes (ambiguous residues) :: 0 of 51
            Pseudo Genes (frameshifted)       :: 16 of 51
            Pseudo Genes (incomplete)         :: 40 of 51
            Pseudo Genes (internal stop)      :: 2 of 51
            Pseudo Genes (multiple problems)  :: 7 of 51
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:37:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 958967
            Orig. end                         :: 980872
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP118233.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21905
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /product="RiPP-like"
                     /region_number="6"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..21905
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="interleaved"
                     /product="RRE-containing"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..21905
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11905](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11905)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            complement(561..962)
                     /db_xref="GeneID:91355378"
                     /locus_tag="PVK74_RS04465"
                     /old_locus_tag="PVK74_04465"
     CDS             complement(561..962)
                     /codon_start=1
                     /db_xref="GeneID:91355378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286004.1"
                     /locus_tag="PVK74_RS04465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_04465"
                     /product="VOC family protein"
                     /protein_id="WP_043324537.1"
                     /transl_table=11
                     /translation="MTPQFDLVGAVVTDMARTLDFYRRLGLPIPAGAETEGHVEVTLPN
                     GVRLAWDTVEVIRSFHPDFDPSGGNNRMSLAFRCADPAEVDRWYAELTAAGHHGELPPW
                     DAFWGQRYAVLHDPDGNGVDLFAPLPAGD"
     gene            1142..1300
                     /db_xref="GeneID:91355379"
                     /locus_tag="PVK74_RS04470"
                     /old_locus_tag="PVK74_04470"
     CDS             1142..1300
                     /codon_start=1
                     /db_xref="GeneID:91355379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787270.1"
                     /locus_tag="PVK74_RS04470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_04470"
                     /product="hypothetical protein"
                     /protein_id="WP_166456093.1"
                     /transl_table=11
                     /translation="MTHLAYLDAGSGSLIVQAVVGGVAGVAVAAKLYWRRLVSRFRRQP
                     SDQGPTA"
     gene            1297..2712
                     /db_xref="GeneID:91355380"
                     /locus_tag="PVK74_RS04475"
                     /old_locus_tag="PVK74_04475"
     CDS             1297..2712
                     /codon_start=1
                     /db_xref="GeneID:91355380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286006.1"
                     /locus_tag="PVK74_RS04475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_04475"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_274478263.1"
                     /transl_table=11
                     /translation="MTVPDTGVRVEPGSFRDPGNRVFHRGEEVLRGLDERSARDWRALS
                     VTDFFRRAAERGQIVATEELTPTPVDTRWAAVLRHERIPFVSHPYEWSYAMLRDAALLH
                     LDVLRAALEAGFTTKDGSAYNVQWRGARPVFIDVGSFEALRDGEPWAGYRQFCQTLLYP
                     LLIQAHLGLDFQPFLRARVDGVEPDQMRRLFGGARRWRAGVPTHVHLHGAMQARNSAAS
                     TTDVRAQLRAAGFSRELALATVRGLTKLVHRLDHRPGDSHWADYQRTCAYSVPDRQAKE
                     EFVDRAVAATGGGSALDLGANDGRYARIAARHAAHVVAVEQDPAVVDTLYRALRDEGET
                     RILPLVMDLADPSPGGGWRGVERAAFADRARADVVLALAVVHHLAIGRNVPLPEVLDQL
                     TALTATGGSLVVEFVHPDDPMARRLLANKPDGLFPDYRRDAFEALLARRGRVVARTELP
                     SGTRTLYQVVVGG"
     gene            2705..4750
                     /db_xref="GeneID:91355381"
                     /locus_tag="PVK74_RS04480"
                     /old_locus_tag="PVK74_04480"
     CDS             2705..4750
                     /GO_function="GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013477023.1"
                     /locus_tag="PVK74_RS04480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_04480"
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="WP_274478264.1"
                     /transl_table=11
                     /translation="MAERTLAPPRDHTAGPDRRERPQWWRSELARLAEVTALVGLVVTQ
                     PLLDVLGRSPDFFLFHRASRGDVLLLVALIALAPTVPFALLGALAVPAGRLIRAAVHTT
                     FVGLLLAALAVQAGRHVTPLRGVPLLVVAGVAGAAGAAAHRRWRAPRRVLRVAAAGPLV
                     FVGLFLFASPASAVVLPRGEGGAAGIAGAGAHPPVVMIVLDELPLVSLLGPDGRIDAER
                     YPNFAALAAGSTWYPNATGVSGWTPYALPAMLTGRYPEQGAAPHYSQYPDNLFTALGGL
                     YRIKAEESITRLCPPSRCEQATTPEQGLGVLVRESGKLMGRIAAPVDSRVDPEDSYRER
                     TAAEAGLDAAEPVPDDPKFRWDTLDDNQPARFTSFLAGLRPDPRPTLHFLHLLMPHSPW
                     AYLPSGAHYAAPEDLPNDGTGWVDLARARHLAQLGYTDRLIGETLRTLRATGLYDKALV
                     VVTADHGVSFRRDWQGRGMDAIEHAANEVAWVPMFVKEPGQRAGRVDDRNWEHVDLLPT
                     IADETHMRVPWQMDGRSAKAAPRERADKRFYDRPGQPVTITGGVPAPLPPPAADPLVGT
                     RVGNVPMGGSATVANRDAFDAVDPARGGLPALVWGTVPDDVPDGTRLAVAVNGTVGAVA
                     PVVPPDAGGRRFAAFLPDDRLFAAGANRLDLYRVGDDGALRRLTLS"
     protocluster    3055..15004
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[8054:10004](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(8055..10004)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
     misc_feature    complement(4771..4785)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 23.51"
                     /tool="antismash"
     misc_feature    4814..4832
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.96"
                     /tool="antismash"
     gene            4927..6210
                     /db_xref="GeneID:91355382"
                     /locus_tag="PVK74_RS04485"
                     /old_locus_tag="PVK74_04485"
     CDS             4927..6210
                     /EC_number="2.3.3.16"
                     /GO_function="GO:0046912 - acyltransferase activity, acyl
                     groups converted into alkyl on transfer [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018252835.1"
                     /locus_tag="PVK74_RS04485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_04485"
                     /product="citrate synthase"
                     /protein_id="WP_187693419.1"
                     /transl_table=11
                     /translation="MTEVKLDHPGGQLSMPVQSAVEGPAGIGVSKLLKETGMTTYDPGF
                     VNTASCSSAITYIDGDAGILRYRGYPIDQLAEKSSFLEVSYLLIYGELPTQAQLSEFSE
                     RIRRHSLLHEEMRRFFDGFPRDAHPMAVLSSAVSAISTFYQDSLDPFDSEHVEMSTVRL
                     MAKVPTIASYAYKKSIGQPLLYPDNSLGYVENFLRMTFGVPAEPYEVDPVVARVLDMLF
                     ILHADHEQNCSTSTVRLVGSSNANLFASVSAGVNALFGPLHGGANQAVLEMLQKIQADG
                     GDVRSFVQKVKDKQDGVKLMGFGHRVYKNYDPRAAIVKKAAQDVLGRMSKPDPLLDLAV
                     QLEEIALADDFFVSRRLYPNVDFYTGLIYKAMGFPTKMFTVLFALGRLPGWIAQWREMI
                     NDPETKIGRPRQIYTGATEREYVPADKR"
     gene            complement(6389..7786)
                     /db_xref="GeneID:91355383"
                     /locus_tag="PVK74_RS04490"
                     /old_locus_tag="PVK74_04490"
     CDS             complement(6389..7786)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355383"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013477022.1"
                     /locus_tag="PVK74_RS04490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_04490"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_274478265.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 3.8e-38,
                     bitscore: 129.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTLRVGAQPATATDRLHRPTLTSRPAPPSPAGAGPRTRRILMLS
                     WEYPPVLVGGLGRHVHALSVTLAAAGHEVTVVTRHAEGAPLEEYADGVRIVRAAEDPVT
                     FPLATGSLLAWTMAFNHTLTRAALRAASSGAYDVIHAHDWLVAHTAMTLREHLDVPLVT
                     TIHATEAGRHQGWLPEEMNRTIHGVEHWLAGESGRVIVCSGYMRDEVGALFGVDAARVD
                     VVPNGVEPHRWRVPASAVAAARARFAADGPLVTFAGRLVYEKGVQHLLAGLPRLRDRHP
                     GLRAVIVGDGPYRADLEAEVHRLGLGGTVSMPGFLGGTDLPAVMAASDCFAVPSIYEPF
                     GMVALEGAAAGAPLAVARTGGLAEIVEPGVTGMTFAPHDPDGLAEAVHALLSDRDRARV
                     LARRARAMVHERYGWAAIASRTAAAYAAAIAGDPSFTAARAQHRMTHGRPTPRVPEGNL
                     LTAAGLR"
     gene            complement(8055..10004)
                     /db_xref="GeneID:91355384"
                     /locus_tag="PVK74_RS04495"
                     /old_locus_tag="PVK74_04495"
     CDS             complement(8055..10004)
                     /codon_start=1
                     /db_xref="GeneID:91355384"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03604.1"
                     /locus_tag="PVK74_RS04495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_04495"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_274478266.1"
                     /sec_met_domain="YcaO (E-value: 2.7e-70, bitscore: 236.2,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 8.6e-88, bitscore:
                     293.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDVTTTPAVPAPSDVAPRPGLRILGVGALRRAVEQALGAAPVTD
                     VDVFVVDGPPEDVDVAARAAADAGRSFLPVYTTPRGVRIGPFVTPGRPGCHHCLQVRQR
                     RARTTGTPHRSALWQGLYDGTVQPARPVLGPPVRAAVAALVADELRRVAQGGDGRCAEA
                     VLEVATASMAVKRHRFVPEPGCPVCGPLPDDGPAAGTFTLTSRPKRAPDDYRARSLPDE
                     HLALLAALHDEETGLLSSITVHHNHPMVLAGAIGGPLCCGELAGYGRTFTYPASVAVAV
                     AEALERLGGNVPRARRTVTRASFRELGPRRAVEPTEFGLPPAPPDDHAVAYDPDRPVEW
                     VYAYSFRRGGPVLVPETFAYYGSHGMGFGPECSNGCALGANLEEAILHGIFEVAERDAF
                     LSTWYARLPVPRVDPMTSADPMTRVLVDWIQRTTGSRLDVFDITMPEGVPAVWLMLVDE
                     EVRPGRPRAFCGAGAHLDPERALWSALVELASVAEATREMVAEDTTAPGLVADSDLVRT
                     MEDHLLAAADPDAWPRFAFLYERDEIRSMAEAFPTAARYRPAADLLDDLRHVTGRYLDE
                     GLDVVVVDQTAREQEAVGLTSVKVLIPGLLPMTFGHRNRRVDLPRLRELPVRLGHRAEP
                     LAPEEINPYPHPFP"
     gene            complement(10001..11905)
                     /db_xref="GeneID:91355385"
                     /locus_tag="PVK74_RS04500"
                     /old_locus_tag="PVK74_04500"
     CDS             complement(10001..11905)
                     /codon_start=1
                     /db_xref="GeneID:91355385"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Thiopeptide_F_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Heterocycloanthracin_C_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PVK74_RS04500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PVK74_04500"
                     /product="hypothetical protein"
                     /protein_id="WP_274478267.1"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 2.7e-19,
                     bitscore: 67.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     7.4e-13, bitscore: 46.7, seeds: 5, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVKLRDDLMYVPVDDGVYLETGLAGTHLAGASAYGLVQRLAPHL
                     DGTRTVEALTAGLPPAQRQLVTDLVRMLVRRGIARDLDSEPPHTLRDWELDTYRDSIAF
                     AEHVSDAPLSRFEAFRDGRVLLVGAGAGMLALVQTLFELGLRTASLVETTETGTERDGF
                     RRIVQRRRAEDPTTGLTLLDAAAALDTDEGLAGLLTGYDAVLHCAARPMAGRATRLNRA
                     ARAIGVPVLHAVPGGAEAWIGPTGGGITGGCWECGLLSRQGAGLPPGDADEPDTTSEWL
                     SAPVCGLIGAALGFAYLRHRVGAESTATNRMTRVDLETAVTSEHLLDVHPRCRSCRPPA
                     PYADLAAHVDAMAARTPVGVEEFVARMPFLVDARLGPLLAIDTGAHSQISVSCVEATVV
                     DLAGGAPRLLTAVGASREQALLRAATAALETLAARACAGDAATRWWDTARGAVVDAQPD
                     GVVIASGHTWAEARGRAILKLRRAAATPPEVADGGPPGGWLDRARWPEPTRVMAHELAL
                     LGHEPRAWHDGSSTPTVFVAVGGGWVARSCATDTDTALANAMQAAVAVLTGRRPDGAEI
                     GPDAGGYDWDTALPPLLRELARDGRSLLVRPADSLPRAQRVMPFMIRAAWSPRAGSSA"
     aSDomain        complement(11633..11902)
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_PVK74_RS04500_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="3.40E-15"
                     /identifier="RREFam011.1"
                     /label="PVK74_RS04500"
                     /locus_tag="PVK74_RS04500"
                     /protein_end="91"
                     /protein_start="1"
                     /score="46.7"
                     /tool="antismash"
                     /translation="RVKLRDDLMYVPVDDGVYLETGLAGTHLAGASAYGLVQRLAPHLD
                     GTRTVEALTAGLPPAQRQLVTDLVRMLVRRGIARDLDSEPPHTLR"
     aSDomain        complement(11672..11905)
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_PVK74_RS04500_Thiopeptide_F_RRE.1"
                     /evalue="1.20E-21"
                     /identifier="RREFam004.1"
                     /label="PVK74_RS04500"
                     /locus_tag="PVK74_RS04500"
                     /protein_end="78"
                     /protein_start="0"
                     /score="67.5"
                     /tool="antismash"
                     /translation="MRVKLRDDLMYVPVDDGVYLETGLAGTHLAGASAYGLVQRLAPHL
                     DGTRTVEALTAGLPPAQRQLVTDLVRMLVRRGI"
     gene            complement(11902..12783)
                     /db_xref="GeneID:91355386"
                     /locus_tag="PVK74_RS04505"
                     /old_locus_tag="PVK74_04505"
     CDS             complement(11902..12783)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (13-278). E-value: 3.4e-28. Score:
                     91.1. Matches aSDomain:
                     nrpspksdomains_PVK74_RS04505_TauD.1"
                     /codon_start=1
                     /db_xref="GeneID:91355386"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046: Dioxygenase TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014698.4"
                     /locus_tag="PVK74_RS04505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_04505"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_140946440.1"
                     /sec_met_domain="TauD (E-value: 3.5e-26, bitscore: 91.1,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEQDVPALVGTPTPDAVLAAVAEHGAVLLRGGWRHEDYVALGDA
                     LMTASPYQGGFHDERDVIGGDPTTTTVTRGTQGMPLHREASYAPGAPDLLMFRCERPAA
                     DGGATTLCDGLALLAALPATVRAACEELTLRWESELPTPVWQRMCGTTDPEAAERMLRQ
                     WEPYLRPWESIHIDVDEDAMTVGFGTRCTPPTLFEGVPAFCNSLFISRPQPGEYHDRRL
                     RVRSGTGAPVPEDLVATAADVAARLTVAVPWRSGDVLVVDNSRYLHGRQAFTDAGRAVA
                     VRMGHLRKEGAA"
     aSDomain        complement(11950..12744)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PVK74_RS04505_TauD.1"
                     /evalue="3.40E-28"
                     /label="PVK74_RS04505_TauD.1"
                     /locus_tag="PVK74_RS04505"
                     /protein_end="278"
                     /protein_start="13"
                     /score="91.1"
                     /tool="antismash"
                     /translation="TPDAVLAAVAEHGAVLLRGGWRHEDYVALGDALMTASPYQGGFHD
                     ERDVIGGDPTTTTVTRGTQGMPLHREASYAPGAPDLLMFRCERPAADGGATTLCDGLAL
                     LAALPATVRAACEELTLRWESELPTPVWQRMCGTTDPEAAERMLRQWEPYLRPWESIHI
                     DVDEDAMTVGFGTRCTPPTLFEGVPAFCNSLFISRPQPGEYHDRRLRVRSGTGAPVPED
                     LVATAADVAARLTVAVPWRSGDVLVVDNSRYLHGRQAFTDAGR"
     gene            complement(12776..14359)
                     /db_xref="GeneID:91355387"
                     /locus_tag="PVK74_RS04510"
                     /old_locus_tag="PVK74_04510"
     CDS             complement(12776..14359)
                     /codon_start=1
                     /db_xref="GeneID:91355387"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PVK74_RS04510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PVK74_04510"
                     /product="hypothetical protein"
                     /protein_id="WP_274478269.1"
                     /transl_table=11
                     /translation="MAATRAGVTGRYLAAVRDDTGQPTAYLPPCGKRYPGATRRPLRWP
                     GPGSVPLGDGCLDRLSAMLLGYAPRRAETITLAGLSALTGAPSDTPTPSRLLPGWHTLR
                     RSVPSGGAFHPNEIYLAWAGSPDLAAGVYHYDPPHHCLELLRPGSPAARLDRLLGAAAA
                     PRHALLLTHRPWKNTSKYGAFGYRLGIVDSGVLLAQLLTSPVDATPRLDLDPALAGELL
                     GLDAELEATYAAIEFPAHADVPGTPLASAGPPPATGLDHDRLGHEAAHPSAVALHRARY
                     DRYADAEPPSADRLPADGVPARRLPADRLPVGPAAGRALDLPPARPLDLVAAAARRASA
                     ANLGPGLTAGQVAGILACAAGRAGSPALAALARQPLYPELWCLARAVDGIPADAYRYQP
                     HHHRLVPTGPPGAADDAAAYPHRVDRRMVTRGATLYLVHAGSRPVDQLSPASFHRLHLL
                     AGVALHLAGLAATATGAASRALGGLTADAVAARLGLPDGASPLTQLLVGTPAPRPGVLA
                     AHLTEGNPHG"
     gene            complement(14361..15149)
                     /db_xref="GeneID:91355388"
                     /locus_tag="PVK74_RS04515"
                     /old_locus_tag="PVK74_04515"
     CDS             complement(14361..15149)
                     /codon_start=1
                     /db_xref="GeneID:91355388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014690183.1"
                     /locus_tag="PVK74_RS04515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_04515"
                     /product="ABC-2 family transporter protein"
                     /protein_id="WP_245254740.1"
                     /transl_table=11
                     /translation="MMHEARIYRRLLGAHLRAVLEYRADALLTIGATVLGQLAGLVFVV
                     MVFRQVTALGGWTRWEVLYVCAMVMLAEGVGSLLFEGTWHLGGLVNLGLLDYLLVRPYP
                     VVLQVTGNAVGFNGLGNVGFGAALLGAAAVHLDLAWTPLTVLWAVVLLVSGVLVKLAVN
                     LATNAVVFWLLSPSSSLAASVHTLGDLARYPLTLYGTGLRSLLTLVPVAFVGYFPTAAL
                     LDKGASTTAGALTPVVAAACAAGAWAVFRAGLRRYESAGS"
     gene            complement(15157..15951)
                     /db_xref="GeneID:91355389"
                     /locus_tag="PVK74_RS04520"
                     /old_locus_tag="PVK74_04520"
     CDS             complement(15157..15951)
                     /codon_start=1
                     /db_xref="GeneID:91355389"
                     /inference="COORDINATES: protein motif:HMM:NF017946.4"
                     /locus_tag="PVK74_RS04520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_04520"
                     /product="ABC-2 family transporter protein"
                     /protein_id="WP_274478270.1"
                     /transl_table=11
                     /translation="MRAYLTLARMSWSTLLIYRGEFLLQLTGVVVQTVALFAVWQAVFA
                     GAAGGEVGGLSWEQMKGYLVVAFLTGALLSSFTDAQIAGPVLHGTVALDLVRPIDYQLS
                     RFALSLGYVVGEVLTVAVMAATLVSAFGGAALPAAGQAGLFLLSLLAVVPLKFGLVYLV
                     GLLCFWTGNFHGLSLSRVAVTNILSGALVPIALFPGWLQVVCQLSPFPGIVSTPALIYL
                     GQARGAEAVTLIGVQLLWVLVLWGAARLLWSAGVRRLTAHGG"
     gene            complement(15948..16955)
                     /db_xref="GeneID:91355390"
                     /locus_tag="PVK74_RS04525"
                     /old_locus_tag="PVK74_04525"
     CDS             complement(15948..16955)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355390"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020523102.1"
                     /locus_tag="PVK74_RS04525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_04525"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_274478272.1"
                     /transl_table=11
                     /translation="MPVIEASGLTKRFRIADKQPGLRGSLRHLVRPRHVEHVAVDGVDL
                     SISSGEAVAYVGPNGAGKSTTVKLLTGILHPTAGRVRVCGLDPHRDRHANARNIGVLFG
                     QRSQLWWDLQVRDSLALLRDIHRIPRARYAARLEEFDALLGLGRLLPVVARQLSLGQRM
                     RADLAAALLHAPPVVFLDEPTIGLDIVARQAVRDFLRAQRASGTTVLMTTHDIGDIEQV
                     CRRLVIIDEGRIIFDGSIDAVRRLVADQRTVHLTLGADWHGDLDADLPGVRLVHDGSAR
                     QIAVTFDHGAYGAGEIVSVVARRAPVVDIRIDEPSIEDVVRRAYAGELSPSVPA"
     gene            complement(16974..18326)
                     /db_xref="GeneID:91355391"
                     /locus_tag="PVK74_RS04530"
                     /old_locus_tag="PVK74_04530"
     CDS             complement(16974..18326)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /db_xref="GeneID:91355391"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025025.4"
                     /locus_tag="PVK74_RS04530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_04530"
                     /product="glycosyltransferase"
                     /protein_id="WP_082930928.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 6.1e-23,
                     bitscore: 80.0, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVEPGRAVELSVVIPTHADAPCLELTLRSLRRQTLDPDRFEVIV
                     VRDGGDGSQYSGIADAGKGLRLHFVERPERGGRAAARNEAARRATAPLLLFLDADSYAT
                     PDLLRRHLDHHRDPSAPAVLMGRRDETGIEHVHAALADQPTMPVPRLRGRGGGDMRFGT
                     EEGPSGDDWLLAGWLFCFTHNASVRRDVFEAVGGFDEGFGLRWGLEDMELFYRVHAHLG
                     VLNRNFAYDDLAAVYHLPHHRNVIQNWNDFMDNLDRVALKYPVVEWEFAGPVDVARAAE
                     RVVHYRRAMDDCVRRSWCRIGPAVQRLAGRLPGDRVLWVGTGSAEAGLPDGALTYDYGA
                     PAGPANFHLVGIRPPVAADSLDAVVSVDFWRYLYWEDLCQFVNVAGALADEVHLVSTGA
                     ELSARFDPDPASLGYLGRVMGAAFETTLTEVDGLGTVLRLRPHHRAAVAAG"
     misc_feature    18306..18319
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    complement(18416..18431)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.47"
                     /tool="antismash"
     gene            complement(18421..18639)
                     /db_xref="GeneID:91355392"
                     /locus_tag="PVK74_RS04535"
                     /old_locus_tag="PVK74_04535"
     CDS             complement(18421..18639)
                     /codon_start=1
                     /db_xref="GeneID:91355392"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PVK74_RS04535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PVK74_04535"
                     /product="hypothetical protein"
                     /protein_id="WP_113973761.1"
                     /transl_table=11
                     /translation="MGESRNLSIDLSDLDTTAVSWSGAGDEASAGLYAMPTGGGITLTD
                     PSAMGKGSCGGAACQGRPIQWCCVNCH"
     misc_feature    18942..18960
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            19183..21303
                     /db_xref="GeneID:91355393"
                     /gene="glgX"
                     /locus_tag="PVK74_RS04540"
                     /old_locus_tag="PVK74_04540"
     CDS             19183..21303
                     /EC_number="3.2.1.196"
                     /GO_function="GO:0004133 - glycogen debranching enzyme
                     activity [Evidence IEA]"
                     /GO_process="GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355393"
                     /gene="glgX"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788443.1"
                     /locus_tag="PVK74_RS04540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_04540"
                     /product="glycogen debranching protein GlgX"
                     /protein_id="WP_274478273.1"
                     /sec_met_domain="CBM_48 (E-value: 4.8e-20, bitscore: 70.1,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase (E-value: 4.7e-16, bitscore:
                     57.8, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVWPGESYPLGATYDGMGTNFAIFSEVAEKIELCLFDEWDIGTE
                     RRVELREVDAYVWHAYIPGVEPGQRYGYRVHGPWNPAEGLRCNPHKLLLDPYAKAVDGE
                     IMWHPSVYDYEVGGDPDRMNTEDSAPYMPKSVVVNPYFDWGNDRPPRTPYHHSVIYEAH
                     VRGLTMRHPGIPEELRGTYAAIASPVMIEHFKRLGVTAVELMPVHEFVHDHRLADLGLR
                     NYWGYNTIGFFAPHHGYSALGRLGQQVQEFRGMVKALHAAGIEVILDVVYNHTAEGNHL
                     GPSLSFKGIDTPSYYRLSEDDRRYFVDYTGTGNSLNVRSPHSLQLIMDSLRYWVTEMHV
                     DGFRFDLAATLAREFYEVDRLSTFFEVVQQDPVVGRVKLIAEPWDVGPGGYQVGNFPPQ
                     WTEWNGKYRDTVRDFWRGEPATLAEFASRISGSADLYQDDGRRPFHSINFVTCHDGFTL
                     ADLVSYNDKHNEANGEDNRDGESHNRSWNCGVEGETDDPGVRALRARQRRNFLATLMLS
                     QGVPMLGHGDELGRTQHGNNNAYCQDSEIAWVDWDRADDELLDFVRRLTDFRNRHQVFR
                     RRRFFTGLPVGGRAAGSGLPDLAWYTPDGREMTGEDWGNDFGRSVALFVNGDGIGERGQ
                     YGQRHRDDSFLLLFNAHDAPLDFTLPGEEFGSRWELVISTAEPDPEKTTLVEAGGTVCV
                     PDRSLLVLERTA"
     misc_feature    21566..21580
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.15"
                     /tool="antismash"
ORIGIN
        1 cggtccgcgc cgggggaccg gtggatcggg ctgcgcctgc cgccgggcac cggcccggcc
       61 gtgttcggcg tgcccgccga ggaactgcgc gaccgccgcg tcccgctggc cgacctgtgg
      121 ggccgcgccg ccgccgaggt gaccgagcgg gtcgaggcgg cgctggccgc gccgggcgcc
      181 ggtagcgccg ccggggtgct cacccgggtc gcccgcgacc ggctgcgtgc ggccggcggc
      241 cccgacccgg tcggcgcgcg tgtcgccgcc cgcctggccg ccggggccac cgtcgccgcg
      301 accgccgccg aggtcggcct cggcgcgcgg gccctgcacc gccgcagcct gaccctgttc
      361 gggtacggcc cgaagacgct cgcccgcatc ctgcggatgc gccgggcgct ggacctggcc
      421 cgcgccggcg cgccgctcgc cgaggtggcc gcgcgcagcg ggtacgccga tcaggcccac
      481 ctgacccgcg aggtgcggga gctggccggg gtgcccccgt cgcggctgct cgccccggcc
      541 accgcctgac cggccgcctt tcagtcgccc gccggcagcg gggcgaacag gtccacgccg
      601 ttgccgtccg ggtcgtgcag gaccgcgtac cgctggcccc agaacgcgtc ccacgggggc
      661 agctccccgt ggtggccggc ggcggtcagc tcggcgtacc agcggtccac ctcggccggg
      721 tcggcgcacc ggaaggccag gctcatccgg ttgttgccgc cggacgggtc gaagtcgggg
      781 tggaagctgc ggatcacctc gaccgtgtcc caggccagcc gtacgccgtt cggcagggtg
      841 acctccacgt gcccttccgt ctcggcgccg gccgggatcg gcagccccag ccgccggtag
      901 aagtcgagtg tgcgggccat gtcggtgacc acggccccga ccagatcgaa ctgcggtgtc
      961 atggcgtcac ggtaggcgcg accggtccgg cccgtcttga acggatcgga cgggggacga
     1021 gtggccggtg tggccccgcg tgcgacgccc gaggcgttac ggtgggggac aagtccggcg
     1081 cgaagcatga aagctcgcat tccgggcgcg cactgacgac cggcgacgga aggaagcagc
     1141 cgtgacccac ctggcctacc tggacgcggg atcgggcagt ctcatcgtgc aggcggtggt
     1201 cggcggcgtg gccggagtgg ccgtggccgc caagctctac tggcgccgcc tggtgtcccg
     1261 gttccgccgc cagcccagcg accagggccc cacggcgtga cggtccccga caccggcgtc
     1321 cgcgtcgagc ccggctcctt ccgcgacccc ggcaaccggg tgttccaccg gggcgaggag
     1381 gtgctgcgcg ggctcgacga gcgctccgcc cgggactggc gtgcgctgtc cgtcaccgac
     1441 ttcttccgcc gcgcggccga gcgggggcag atcgtcgcca ccgaggagtt gaccccgacc
     1501 cccgtcgaca cgcggtgggc tgcggtgctg cggcacgagc ggatcccgtt cgtctcgcac
     1561 ccctacgagt ggtcgtacgc gatgctgcgc gacgccgcgt tgctgcacct cgacgtgctg
     1621 cgcgccgccc tggaagccgg cttcaccacc aaggacggct cggcgtacaa cgtgcagtgg
     1681 cgcggcgcgc gacccgtctt catcgacgtc ggctcgttcg aggcgctgcg cgacggcgag
     1741 ccctgggccg gctaccggca gttctgccag acgctgctct acccgctgct gatccaggcc
     1801 cacctcgggc tggacttcca gccgttcctg cgggcccgcg tcgacggcgt cgagccggac
     1861 cagatgcgcc ggctgttcgg cggcgcccgg cgctggcggg ccggcgtgcc cacccacgtg
     1921 cacctgcacg gcgcgatgca ggcccgcaac tccgccgcga gcaccaccga cgtccgcgcc
     1981 cagttgcgcg ccgccggctt ctcccgcgaa ctggcgctgg ccacggtacg cgggctgacg
     2041 aaactggtcc accgcctcga ccaccggccg ggcgacagcc actgggcgga ctaccagcgc
     2101 acctgcgcgt actcggtgcc ggaccggcag gccaaggagg agttcgtcga ccgcgcggtg
     2161 gccgccaccg gcggcggctc ggcgctggac ctgggcgcca acgacggccg gtacgcccgc
     2221 atcgccgccc ggcacgccgc gcacgtcgtc gcggtcgagc aggacccggc ggtggtcgac
     2281 acgctctacc gcgcgctgcg cgacgagggc gagacgcgga tcctgccgct ggtgatggac
     2341 ctggccgacc cgtcgcccgg cggcggctgg cgcggcgtcg agcgggccgc gttcgccgac
     2401 cgggcccgcg ccgacgtggt gctcgccctg gccgtcgtgc accacctggc gatcgggcgc
     2461 aacgtgccgc tgcccgaggt gctggaccag ctcaccgcgc tcaccgccac cggcggcagc
     2521 ctggtggtgg agttcgtcca cccggacgat ccgatggccc gccgcctgct cgccaacaag
     2581 cccgacggcc tgttcccgga ctaccggcgc gacgccttcg aggcactgct ggcccgccgg
     2641 ggccgggtgg tcgcccgcac cgagctgccg tccggcaccc ggacgctcta ccaggtggtg
     2701 gtgggtggct gagcgcaccc tcgcgccacc ccgggaccac acggccggcc cggaccggcg
     2761 ggaacgcccg cagtggtggc ggtccgagct tgcgcggctg gcggaggtga ccgcgttggt
     2821 cgggctggtg gtgacccagc cgctgctcga cgtgctcggc cgcagccccg acttcttcct
     2881 gttccaccgc gcgtcccggg gcgacgtgct gctcctggtc gccctgatcg cgctcgcgcc
     2941 gacggtaccg ttcgcgctgc tcggcgcgct ggcagtgccc gccggacgcc ttatccgggc
     3001 cgccgtgcac accaccttcg tcggcctgct gctcgccgcg ctggccgtcc aggccggccg
     3061 gcacgtcacg ccgcttcggg gcgtacccct gctcgtcgtc gccggtgtgg ccggagccgc
     3121 cggggcggcc gcgcaccggc ggtggcgggc gccccggcgg gtgctgcggg tggccgccgc
     3181 cgggccgctg gtgttcgtcg ggttgttcct gttcgcctcg cccgcctcgg cggtggtgct
     3241 gccgcgcggc gagggcggcg cagccgggat cgccggcgcg ggcgcgcacc cgccggtggt
     3301 catgatcgtg ctggacgagc tgccgctggt ctccctgctc ggcccggacg gacgcatcga
     3361 cgccgagcgc tacccgaact tcgccgcgct cgcggccggg tcgacgtggt accccaacgc
     3421 gaccggcgtc agcggctgga cgccctacgc gctgccggcg atgctcaccg ggcgctaccc
     3481 ggagcagggc gcggcgccgc actactcgca gtacccggac aacctgttca ccgcgctcgg
     3541 gggcctctac cggatcaagg ccgaggagag catcacccgg ctctgtccgc cgagccgctg
     3601 cgagcaggcc accacgccgg aacaggggct cggggtgctg gtccgggaga gcggcaagct
     3661 gatgggccgg atcgccgcgc cggtggacag ccgcgtcgac ccggaggact cctaccgcga
     3721 gcggaccgcc gccgaggccg ggctggacgc cgccgagccg gtgccggacg accccaagtt
     3781 ccgctgggac accctcgacg acaaccagcc ggcccggttc acctcgttcc tggccgggct
     3841 gcgccccgac ccccggccca cgctgcactt cctgcacctg ctgatgccgc actcgccgtg
     3901 ggcgtacctg ccgtccgggg cgcactacgc cgcgccggag gacctgccca acgacgggac
     3961 cggctgggtc gacctggccc gcgcccggca cctggcccag ctcggctaca ccgaccggct
     4021 gatcggcgag acgctgcgga cgctgcgcgc caccggcctc tacgacaagg cgctggtggt
     4081 ggtcaccgcc gaccacgggg tgagcttccg gcgggactgg caggggcggg ggatggacgc
     4141 catcgagcac gccgccaacg aggtggcctg ggtgccgatg ttcgtcaagg aacccggcca
     4201 gcgcgccggc cgggtggacg accgcaactg ggagcacgtg gacctgctgc ccacgatcgc
     4261 cgacgagacc cacatgcggg tgccctggca gatggacggc cggtcggcca aggcggctcc
     4321 gcgcgagcga gccgacaaac gcttctacga ccgccccggc cagccggtga cgatcaccgg
     4381 cggggtgccc gccccgctcc cgccgccggc cgctgatccg ctcgtcggga cccgggtcgg
     4441 gaacgtgccg atgggcgggt ccgccacggt ggcgaaccgg gacgcgttcg acgcggtcga
     4501 cccggcgcgc ggcggcctgc ccgcgctggt ctgggggacg gtcccggacg acgtgcccga
     4561 cgggacacgg ctcgccgtcg cggtgaacgg cacggtcggg gcggtggcgc cggtggtgcc
     4621 cccggacgcc ggtggccggc ggttcgcggc gttcctcccc gacgaccggc tcttcgccgc
     4681 cggcgccaac cggctcgacc tctaccgggt cggcgacgac ggggcgctgc ggcggctcac
     4741 gctgtcgtga cgggcccctg gccggcgccc atggtcgcgc tcccaaccgg tttccggacc
     4801 gcctggccgg gaaacaggtg acgcacacct caccccgaaa ccatgacgag cggtgttctc
     4861 cgcgccgtga ttacggtaga agcgaaggca attcaacgaa gatcttgccg gcgaagcgag
     4921 gaacagatga cggaagtcaa gctcgaccac cccggtgggc agctgtcgat gccggtgcag
     4981 tccgcggttg agggccccgc cgggatcggg gtgagcaagc tgctcaagga aaccgggatg
     5041 accacgtacg accccggttt cgtgaacacc gcgtcctgct cgtccgccat cacctacatc
     5101 gacggtgatg ccggcatcct gcggtaccgg ggttacccga tcgaccagtt ggccgagaag
     5161 tcctccttcc tggaggtctc ctacctgctg atctacggcg agctgccgac ccaggcgcag
     5221 ctgtcggagt tcagcgagcg gatccggcgg cactcgctgc tgcacgagga gatgcgccgg
     5281 ttcttcgacg gcttcccccg tgacgcgcac ccgatggccg tgctctcctc ggccgtcagc
     5341 gccatctcca ccttctacca ggacagcctg gacccgttcg actccgagca cgtggagatg
     5401 tccacggtgc ggctgatggc gaaggtcccg accatcgcct cgtacgcgta caagaagtcg
     5461 atcgggcagc cgctgctgta cccggacaac tcgctcggct acgtcgagaa cttcctgcgg
     5521 atgacgttcg gcgtgccggc cgagccgtac gaggtcgacc cggtggtggc ccgggtgctg
     5581 gacatgctgt tcatcctgca cgccgaccac gagcagaact gctccacctc caccgtgcgg
     5641 ctggtcggct ccagcaacgc caacctgttc gcctcggtct cggccggcgt gaacgcgctg
     5701 ttcggcccgc tgcacggcgg cgccaaccag gccgtgctgg agatgctcca gaagatccag
     5761 gccgacggcg gcgacgtccg ctccttcgtg cagaaggtga aggacaagca ggacggcgtg
     5821 aagctgatgg gcttcgggca ccgggtctac aagaactacg acccgcgtgc cgccatcgtg
     5881 aagaaggccg cccaggacgt gctcggccgg atgtccaagc cggacccgct gctcgacctc
     5941 gcggtgcagc tggaggagat cgcgctcgcc gacgacttct tcgtgtcccg ccggctctac
     6001 ccgaacgtgg acttctacac cggtctgatc tacaaggcca tgggcttccc gacgaagatg
     6061 ttcacggtgc tgttcgcgct gggccgcctg cccggctgga tcgcgcagtg gcgcgagatg
     6121 atcaacgacc cggagaccaa gatcggtcgc ccgcggcaga tctacaccgg cgccaccgag
     6181 cgggagtacg tcccggccga caagcgctga gcgtgcaagg aagggcccct tcttaacgcc
     6241 tccggtagag gaggggcccc cttttaacac gcggacgacg aaggccgccg acccgagcag
     6301 ggtcggcggc cttcgtcctg tgcaccgggg ggaggggcgt taacaagggg cccttcctct
     6361 acccgaggcg ttaatagggg gcccttcctt accgcaggcc ggcggcggtg aggaggttgc
     6421 cctcggggac gcgcggcgtg ggccggccgt gtgtcatgcg gtgctgggcg cgggcggcgg
     6481 tgaacgacgg gtcgccggcg atggcggcgg cgtacgcggc agccgtgcgg gacgcgatgg
     6541 ccgcccagcc gtaccgctcg tggaccatgg cgcgggcccg ccgggcgagc acgcgggccc
     6601 ggtcccggtc cgacagcaac gcgtgcaccg cctcggcgag cccgtccggg tcgtgcgggg
     6661 cgaacgtcat cccggtgacg cccggctcga cgatctcggc caggccgccg gtacgggcca
     6721 ctgccagcgg cgcgcccgcg gcggccccct ccagcgccac catgccgaac ggctcgtaga
     6781 tgctgggcac cgcgaagcag tccgaggcgg ccatcacggc gggcaggtcg gtgccgccga
     6841 ggaacccggg catgctgacg gtgccgccca gcccgaggcg gtgcacctcg gcctccaggt
     6901 ccgcccggta cggcccgtcg ccgacgatca ccgcgcgcag gccggggtgc cggtcgcgca
     6961 gccggggcag cccggccagc aggtgctgta cgcccttctc gtacaccagg cggccggcga
     7021 acgtgaccag cgggccgtcg gcggcgaacc gcgcccgggc ggcggcgacg gccgacgcgg
     7081 gcacccgcca gcggtgcggc tcgacgccgt tgggcaccac gtcgacgcgg gcggcgtcca
     7141 cgccgaacag cgcgcccacc tcgtcgcgca tgtagccgga gcacacgatc acgcgcccgg
     7201 actcgccggc gagccagtgc tcgacgccgt ggatggtgcg gttcatctcc tccggcagcc
     7261 agccctggtg ccggcccgcc tcggtggcgt ggatggtggt cacgagcggc acgtccaggt
     7321 gctcgcgcag cgtcatcgcg gtgtgcgcga cgagccagtc gtgggcgtgg atgacgtcgt
     7381 aggcgccgga ggaggcggcg cgcagcgcgg cccgcgtcag cgtgtggttg aacgccatcg
     7441 tccaggccag cagtgacccg gtggccaggg ggaaggtgac cgggtcctcg gcggcgcgga
     7501 cgatacggac gccgtcggcg tactcctcca ggggagcgcc ctcggcgtgg cgggtgacga
     7561 ccgtgacctc gtgcccggcg gcggccagcg tcacggacag cgcgtggacg tggcggccga
     7621 gtccgccgac gagcaccggc gggtactccc acgacagcat caggatgcgc cgggtccggg
     7681 gcccggcccc ggccggcgac ggcggggccg ggcgggaggt gagagtgggc cggtggagcc
     7741 ggtccgtcgc ggtggcgggc tgcgcgccga cccgcagagt ggtcacgtcg atctccgtcc
     7801 atgcagggtg aggcacgccg gcagcggtgg cggcgtcgag cggtggtcag gagcgaccgg
     7861 acggccggcc gggcgccggc accagctcgc cgacgacggc ctggccggat accgatcgcg
     7921 ggccaccggg agggtgctga cgtcgatcgg caaccggaac cgtccagtca ccctgccaac
     7981 ctactgtgcc ggatcctctc gcgcgcggtg agcgatcctc atcactctcc gacgcctccg
     8041 cgcacatggg acggtcacgg gaacgggtgc ggatacgggt tgatctcctc cggggcgagc
     8101 ggttcggccc ggtgtccgag ccggaccggc agctcgcgca gccggggcag gtcgacgcgc
     8161 cggttgcggt gaccgaacgt catcggcagc agccccggga tcagcacctt cacgctggtg
     8221 aggccgacgg cctcctgctc gcgggcggtc tggtcgacga ccaccacgtc caggccctcg
     8281 tcgaggtagc gtccggtcac gtgccgcagg tcgtcgagca ggtccgcggc cgggcggtag
     8341 cgcgccgccg ttgggaacgc ctccgccatg gaccggatct cgtcgcgctc gtacaggaac
     8401 gcgaagcgcg gccaggcgtc cgggtcggcc gccgccagca ggtggtcctc catggtccgg
     8461 accaggtcgg agtcggcgac caggccgggg gcggtggtgt cctcggcgac catctcccgg
     8521 gtggcctcgg cgacgctggc gagctccacc agcgcggacc acagggcgcg ctccgggtcc
     8581 aggtgcgccc cggcgccgca gaacgcccgg ggacgtcccg gccgcacctc ctcgtcgacg
     8641 agcatcagcc agaccgccgg gacgccttcg ggcatggtga tgtcgaagac gtccaggcgg
     8701 ctgccggtgg tgcgctggat ccagtcgacg agcacgcggg tcatcgggtc ggcggaggtc
     8761 atcgggtcca cgcgcggcac cggtagccgg gcgtaccagg tggacaggaa ggcgtcccgt
     8821 tcggcgactt cgaagatgcc gtgcaggatc gcctcttcga ggttcgcgcc cagcgcgcag
     8881 ccgtttgagc actccggacc gaaacccatg ccgtgcgagc cgtagtaggc gaaggtctcc
     8941 ggcaccagca ccgggccgcc gcgccggaac gaataggcgt acacccattc cacgggccgg
     9001 tccgggtcgt atgcgaccgc gtggtcgtcg ggcggcgcgg gcggcagccc gaactccgtc
     9061 ggctcgacgg cccgccgcgg tccgagctcg cggaacgagg cgcgggtgac ggtacggcgg
     9121 gcgcgtggca cgttgccgcc gagccgttcc agcgcctcgg cgacggcgac ggccacgctc
     9181 gccgggtagg tgaaggtccg gccgtagccg gccagttcac cacagcacaa cgggccaccg
     9241 atcgcgccgg cgaggaccat cggatggttg tggtggacgg tgatcgacga cagcagcccg
     9301 gtctcctcgt cgtgcagcgc cgccagcagg gcgaggtgct cgtcgggaag gctgcgggcc
     9361 cggtagtcgt ccggtgcccg cttcggccgg gacgtcagcg tgaaggtgcc ggcggccggg
     9421 ccgtcgtccg gcaacgggcc gcacaccggg cagccgggtt cggggacgaa ccggtgccgc
     9481 ttgacggcca tcgaggccgt ggcgacctcc agcaccgctt ccgcgcaccg gccgtcgccg
     9541 ccctgcgcga cccggcgcag ctcgtcggcc acgagcgcgg cgaccgcggc gcgtaccggc
     9601 gggccgagga cgggccgggc gggctgcacg gtgccgtcgt agagcccctg ccacagcgcg
     9661 gaccggtgcg gtgtcccggt ggtccgcgcc cggcgttgcc gcacctggag gcagtggtgg
     9721 cagcccggcc ggccgggtgt gacgaacggg ccgatccgta cgccgcgcgg cgtggtgtac
     9781 accggcagga aggaccggcc ggcgtcggcg gcagcccggg cggccacgtc gacgtcctcc
     9841 ggtggcccgt cgacgacgaa gacgtcgacg tcggtgaccg gggcggcgcc cagcgcctgt
     9901 tccaccgccc ggcgcagggc gccgacgccg aggatccgca ggccgggacg cggcgccacg
     9961 tcggacgggg cggggacggc cggtgtggtc gtgacgtcgg tcatgcgctg ctccccgctc
    10021 gtggcgacca cgccgccctg atcatgaacg gcatcacccg ctgcgcccgg ggcagcgagt
    10081 cggcgggccg caccagcagc gaccgtccgt cccgtgccag ctcgcgtagc agcggcggca
    10141 gcgccgtgtc ccagtcgtag ccgcccgcgt ccggcccgat ctcggcgccg tccgggcggc
    10201 gtccggtcag gacggcgacc gcggcctgca tcgcgttcgc cagggcggtg tccgtgtcgg
    10261 tggcgcagct gcgggcgacc catccgccgc cgacggcgac gaacacggtc ggggtgctcg
    10321 atccgtcgtg ccacgcccgc ggctcgtggc cgaggagggc cagctcgtgt gccatgacgc
    10381 gggtcggctc cggccaccgc gcccggtcga gccagccgcc gggcggccca ccgtcggcga
    10441 cctcgggtgg ggtcgcggcc gcgcgtcgca gtttcaggat cgcccggccg cgcgcctccg
    10501 cccaggtgtg accgctggcg atcaccacgc cgtccggctg tgcgtcgacg acagcgccac
    10561 gcgcggtgtc ccaccacctc gtggcggcgt cgccggcgca ggcccgggcc gcgagcgtct
    10621 ccagtgccgc cgtggcggcg cgcagcagcg cctgctcccg gcttgcgccg acggcggtga
    10681 gcagccgcgg tgcgccgccg gccaggtcca cgaccgtcgc ctcgacgcag ctgaccgaga
    10741 tctgcgagtg ggcgccggtg tcgatggcca gcagcgggcc cagccgcgcg tcgaccagga
    10801 acggcatccg ggcgacgaac tcctcgacgc ccaccggcgt gcgggcggcc atcgcgtcga
    10861 cgtgcgcggc gagatcggcg tacggggccg ggggccggca ggagcggcag cgggggtgca
    10921 cgtcgagcag atgctcgctg gtcacagcgg tttccaggtc cacgcgggtc atccggttcg
    10981 tggcggtgct ctccgctccc acccggtggc gcaggtacgc gaacccgagc gccgcgccga
    11041 tcaggccgca gaccggcgcc gacagccact cggacgtcgt gtcgggctcg tcggcgtcac
    11101 ccggggggag cccggcgccc tgccggctga gcaggccgca ctcccagcag ccgccggtga
    11161 tgccgccgcc ggtcgggccg atccacgcct ccgcgccgcc gggcaccgcg tgcaggaccg
    11221 gcaccccgat cgcccgggcc gcccggttca gccgcgtcgc ccgcccggcc atcggacgcg
    11281 cggcgcagtg cagcaccgcg tcgtaccccg tcagcaggcc ggcgagcccc tcgtcggtgt
    11341 cgagggcggc ggccgcgtcc agcagcgtca gcccggtcgt cggatcctct gctcgacggc
    11401 gctgcacgat ccgccggaag ccgtcgcgtt cggtgccggt ctcggtggtc tcgaccagcg
    11461 aggccgtacg cagcccgagt tcgaacagcg tctggacgag cgcgagcatg ccggcgccgg
    11521 cgccgacgag cagcacccgc ccgtcgcgga acgcctcgaa gcggctcagc ggcgcgtcgc
    11581 tgacgtgctc ggcgaacgcg atcgagtccc ggtaggtgtc gagttcccag tcccgcaacg
    11641 tgtgtggcgg ctcgctgtcg aggtcgcggg cgatgccccg ccgcaccagc atccggacca
    11701 ggtcggtgac gagctgccgc tgcgccgggg gcagacccgc ggtcagggcc tccaccgtgc
    11761 gggtgccgtc cagatgcggg gcgagccgct gcacgaggcc gtacgccgac gcgcccgcca
    11821 ggtgcgtgcc ggcgagtccc gtctccaggt acacgccgtc gtcgaccggc acgtacatca
    11881 ggtcgtcgcg gagcttgacc ctcacgcggc cccctccttc cgcaggtgtc ccatccgcac
    11941 cgcgaccgcg cgtccggcgt cggtgaacgc ctgccggccg tgcaggtacc gggagttgtc
    12001 cacgaccagc acgtcaccgg accgccacgg caccgccacc gtcagccgcg cggcgacgtc
    12061 cgcggcggtg gccacgaggt cctcgggcac cggcgcgccg gtaccggagc gcacccgcag
    12121 ccgccggtcg tggtactcgc cgggctgcgg gcggctgatg aacagcgagt tgcagaacgc
    12181 cggcacacct tcgaagaggg tcggtggcgt gcaccgggtg ccgaagccga cagtcatcgc
    12241 gtcctcgtcc acgtcgatgt ggatcgactc ccacggccgc aggtacggct cccactgccg
    12301 cagcatccgc tccgccgcct ccgggtcggt cgtgccgcac atccgctgcc acaccggtgt
    12361 gggcagctcg ctctcccagc gcagcgtcag ttcctcgcag gcggcgcgga ccgtggcggg
    12421 cagggcggcc agcagcgcga gaccgtcgca cagcgtcgtg gccccgccgt cggcggcggg
    12481 ccgctcgcac cggaacatca gcaggtccgg ggcgccgggc gcgtacgacg cctcccggtg
    12541 cagcggcatg ccctgcgttc cccgggtgac tgtggtcgtc gtcgggtcac cgccgatcac
    12601 gtcccgctcg tcgtggaacc cgccctggta cggcgacgcg gtcatcagcg cgtcgccgag
    12661 cgcgacgtag tcctcgtgcc gccacccgcc gcgcagcagc accgcgccgt gctcggcgac
    12721 cgccgcgagc accgcgtccg gcgtgggggt gccgacgagc gccggaacgt cctgttcagc
    12781 catgagggtt cccttcggtg agatgggccg ccagcacccc gggacgcggc gcgggcgtgc
    12841 cgaccagcag ttgtgtcagc ggggacgccc cgtccggcag gccgagccgg gcggcgaccg
    12901 cgtcggcggt gaggccgccc agcgcccggc tcgccgcgcc ggtcgcggtg gcggcgagcc
    12961 cggccaggtg aagggccaca ccggcgagca ggtgcagccg gtggaacgag gccggggaga
    13021 gctggtcgac gggccggctc ccggcgtgca ccaggtagag ggtcgcgccg cgggtgacca
    13081 tccggcggtc gacccggtgc gggtacgccg ccgcgtcgtc ggccgctccc ggcggcccgg
    13141 tcggcaccag ccggtggtgg tgcggctggt agcggtacgc gtccgccggg atgccgtcga
    13201 cggcccgggc gaggcaccag agctccgggt acagcggctg ccgggccagc gccgccaggg
    13261 ccggcgaacc ggcccggccg gcggcgcagg ccaggatgcc ggcgacctgc ccggcggtca
    13321 gccccgggcc gaggttcgcg gcggaggcgc ggcgggcggc ggccgcgacc aggtcgagcg
    13381 gccgggccgg cggcaggtcc agcgcccggc ccgccgccgg acccaccgga aggcggtccg
    13441 ccgggaggcg ccgggccggg acgccgtcgg ccggaagacg gtcggccgag ggtggctcgg
    13501 cgtcggcgta ccggtcgtac cttgcccggt gcagcgccac cgcgctcggg tgggcggcct
    13561 cgtggccgag ccggtcgtgg tccagcccgg tcgccggggg cggcccggcg gacgcaagcg
    13621 gtgtcccggg gacgtccgcg tgcgcgggga actcgatcgc cgcgtaggtg gcctccagtt
    13681 cggcgtcgag tccgagcagc tcaccggcga gcgccggatc gaggtccagg cgcggtgtcg
    13741 cgtccaccgg cgacgtgagc agctgggcca gcaggacacc ggagtcgacg atgcccagcc
    13801 ggtagccgaa cgccccgtac ttgctggtgt tcttccacgg ccggtgggtc agcagcagcg
    13861 cgtgccgggg cgccgccgcg gcaccgagga gccggtcgag ccgggcggcc gggctgcccg
    13921 ggcgcagcag ttccaggcag tggtgcggcg ggtcgtagtg gtagacgccg gccgcgaggt
    13981 cgggggagcc ggcccaggcg aggtagatct cgttggggtg gaacgccccg ccggagggca
    14041 ccgaccggcg cagcgtgtgc cagccgggca gcagccgcga cggcgtgggc gtgtccgacg
    14101 gggcgccggt caacgcggac agtccggcca gcgtgatcgt ctccgcccgg cgtggcgcgt
    14161 acccgagcag catcgcgctg agccggtcga ggcagccgtc gccgagcggc acggaccccg
    14221 ggccgggcca ccgcagcggc cggcgggtcg cgcccgggta ccgcttgccg cacggcggca
    14281 ggtacgccgt cggctgcccg gtgtcgtccc gcaccgccgc caggtacctg ccggtgacgc
    14341 cggcccgcgt ggctgccatc tcagctgccc gcgctctcgt accggcgcaa cccggcccgg
    14401 aagaccgccc acgccccggc cgcgcaggcc gccgcgacga ccggggtgag cgcgcccgcc
    14461 gtggtcgagg cgcccttgtc cagcagcgcg gccgtcggga agtagccgac gaacgcgacg
    14521 ggtacgagcg tcagcagcga gcgcaggccg gtgccgtaca gggtcagcgg atagcgggcc
    14581 aggtcgccca gggtgtgcac gctcgccgcg agcgagctgg acgggctcag cagccagaag
    14641 acgacagcgt tggtggccag gttgaccgcc agcttgacca gcaccccgct gacgagcagc
    14701 accaccgccc agagcaccgt cagcggcgtc caggccaggt cgaggtggac ggccgcggcg
    14761 ccgagcagcg ccgcgccgaa cccgacgttg ccgaggccgt tgaacccgac cgcgttgccg
    14821 gtgacctgga gcaccaccgg gtagggccgg accagcaggt agtccagcag gccgaggttg
    14881 accaggccgc cgagatgcca ggtcccctcg aacagcaggg agccgacgcc ctcggcgagc
    14941 atcaccatgg cgcagacgta cagcacctcc cagcgggtcc acccgccgag cgccgtcacc
    15001 tgccggaaca ccatcaccac gaagaccagc ccggcgagct gaccgagcac ggtcgccccg
    15061 atggtcagga gcgcgtcggc gcggtactcg agcaccgccc gcagatgcgc gccgagcagc
    15121 cggcggtaga tccgtgcctc gtgcatcatc ggccggtcac ccgccgtgcg cggtcagccg
    15181 ccgcacgccc gcggaccaca gcagccgggc cgcgccccac aacaccagaa cccagagcag
    15241 ttgtacgccg atcagcgtca ccgcctcggc gccacgtgcc tgccccaggt agatcagcgc
    15301 cggggtggag acgatgccgg ggaacgggga gagctggcag acgacctgga gccagcccgg
    15361 gaacaacgcg atcggcacca gcgccccgga gaggatgttg gtgaccgcca cccgggacag
    15421 gctcagcccg tggaagttgc cggtccagaa gcacagcagc ccgacgaggt agaccaggcc
    15481 gaacttcagc ggcaccaccg ccagcaggct gagcaggaac agcccggcct gcccggcggc
    15541 gggcagcgcg gcgccgccga acgccgacac cagcgtcgcc gccatcaccg ccaccgtcag
    15601 cacctcaccg acgacgtatc cgagtgacag cgcgaaacgc gagagctggt agtcgatcgg
    15661 ccggaccagg tcgagcgcca cggtgccgtg cagcaccggg ccggcgatct gcgcgtcggt
    15721 gaagctcgac agcagcgccc cggtcaggaa cgccacgacc aggtagccct tcatctgctc
    15781 ccaggacaac ccgcccacct cgccgccggc cgcgccggcg aagaccgcct gccagaccgc
    15841 gaacagcgcc acggtctgca ccacgacccc ggtgagctgg aggaggaact cgccccggta
    15901 gatcagcagc gtcgaccagg acatccgggc cagcgtcagg tacgccctca tgccggcacc
    15961 gacgggctca gctcgccggc gtacgcccgg cgcaccacgt cctcgatgga cggctcgtcg
    16021 atccggatgt ccaccaccgg cgcccggcgg gcgaccaccg agacgatctc gcccgcgccg
    16081 tacgcgccgt ggtcgaacgt gacggcgatc tgccgtgccg acccgtcgtg gaccagccgg
    16141 acgcccggca ggtcggcgtc gaggtcgccg tgccagtcgg cgccgagcgt caggtgcacg
    16201 gtccgctggt cggcgaccag ccggcggacg gcgtcgatcg agccgtcgaa gatgatccgg
    16261 ccctcgtcga tgatcacgag ccggcggcag acctgctcga tgtcaccgat gtcgtgcgtg
    16321 gtcatcagca ccgtggtccc gctcgcgcgc tgggcccgca ggaagtcccg gacggcctgc
    16381 cgggcgacga tgtccagccc gatggtcggc tcgtcgagga acaccacggg cggtgcgtgc
    16441 agcagcgcgg cggccaggtc ggctcgcatc cgctggccga gcgagagctg ccgggcgacc
    16501 accggcagca gccggccgag cccgagcagc gcgtcgaact cctccaggcg tgccgcgtac
    16561 cgggcccggg ggatgcggtg gatgtcgcgc agcagcgcga gggagtcgcg gacctgcagg
    16621 tcccaccaga gctggctgcg ctggccgaac agcacgccga tgttgcgggc gttggcgtgc
    16681 cggtcgcggt gcgggtcgag gccgcagacg cgtacccgcc cggcggtggg gtgcaggatg
    16741 ccggtgagca gcttgaccgt cgtcgacttc ccggcgccgt tgggcccgac gtacgcgacc
    16801 gcctcgccgg aggagatcga caggtcgacg ccgtccaccg ccacgtgctc gacgtgtcgt
    16861 ggccgtacga gatggcgcag cgagccgcgc aggcccggct gcttgtcggc gatccggaac
    16921 cgcttggtca ggccactggc ctcgatcact ggcatcggcg ttgtcgttcc cggtcagccg
    16981 gccgcgacgg cggcacggtg gtgcgggcgc agccgcagca ccgtgccgag gccgtcgacc
    17041 tcggtcaggg tggtctcgaa cgcggcgccc atgacccggc cgaggtagcc caggctcgcc
    17101 gggtccgggt cgaaccgcgc cgagagctcc gcgccggtgg agaccaggtg cacctcgtcg
    17161 gcgagggcac cggcgacgtt gacgaactgg cacaggtcct cccagtagag gtaccgccag
    17221 aagtcgacgc tgaccacggc gtccaggctg tccgcggcga ccggtggcct gatcccgacc
    17281 aggtggaagt tggccggacc ggccggcgcc ccgtagtcgt aggtcagcgc gccgtcgggc
    17341 agcccggcct cggcgctgcc ggtgccgacc cacagcaccc ggtcgccggg caggcgaccg
    17401 gcgagccgct gcaccgccgg cccgatccgg caccaggagc ggcgtacgca gtcgtccatc
    17461 gcccggcggt agtgcaccac ccgctcggcc gcgcgggcca cgtccaccgg cccggcgaac
    17521 tcccactcca cgaccgggta cttgagcgcg acccgatcca ggttgtccat gaagtcgttc
    17581 cagttctgga tgacgttgcg gtggtgcggc aggtggtaga cggcggccag gtcgtcgtag
    17641 gcgaagttgc ggttgagcac accgaggtgt gcgtgcaccc ggtagaagag ctccatgtcc
    17701 tccaggcccc agcgcaggcc gaagccctcg tcgaagccgc cgaccgcctc gaacacgtcc
    17761 cggcgcaccg aggcgttgtg ggtgaagcag aacagccacc cggccagcag ccagtcgtcg
    17821 ccggacggtc cctcctcggt cccgaaccgc atgtcgccgc cgccgcgccc acgcagccga
    17881 ggtacgggca tggtcggctg gtcggccagc gccgcgtgca cgtgctcgat gccggtctcg
    17941 tcgcgccggc ccatcagcac cgccggcgcg gacgggtcgc ggtggtggtc gaggtggcgg
    18001 cgcagcaggt ccggcgtggc gtacgagtcg gcgtcgagga acagcagcag cggcgcggtc
    18061 gcccggcgcg cggcctcgtt gcgggccgcc gcccggccgc cgcgctcggg ccgttcgacg
    18121 aagtgcaggc gcagcccctt gccggcgtcg gcgatgccgg agtactggct gccgtccccg
    18181 ccgtcgcgga cgacgatgac ctcgaagcgg tccgggtcca gcgtctgacg ccgcagcgac
    18241 cgcagcgtga gctccaggca gggggcgtcc gcgtgggtgg ggatcaccac gctcagctcg
    18301 acggctcgac cgggttcaac gctcatctga cgtacctctc cgcttgtccc acgagccgga
    18361 ccgccggccg cgctgacgat gggacggagc cgccggcgat cgccggcggc tccgcgatga
    18421 tcagtggcag ttgacgcagc accactggat cggccggccc tggcacgcgg cgccgccgca
    18481 ggagcccttg cccatggcgg acgggtcggt cagcgtgatc ccgccgcccg tcggcatggc
    18541 gtacagccct gccgacgcct cgtcgccggc gcccgaccag gagaccgctg tggtgtccag
    18601 gtcggacagg tcgatcgaca agttcctgct ttcacccatc gattcatcct cttttcggat
    18661 cgatgtggac agtggaacga agcgtaggcc ggtcctggcg ggattcgcac cgcgctgatg
    18721 taacagggag ataaagcgag gcggaaccgt caattcgcgc aggtgaaggc cggtcgagaa
    18781 cggaaagatt ccgggcggtg acgcggcgta gttccgggat ccactattcg agacgcccag
    18841 gtcaggtggg gtcgaacgat gaatcaccgc atcaattacc tccttctccg atcgcgtgaa
    18901 gccgatgtaa cgagaagata aagtagggga aggtgtcaat gaatgcgggc gaccctctat
    18961 tgtgaagtga cctgcttatt cgccgacccc ggctacggaa tgccgggacg ggtggccccg
    19021 atcgccgcag gcgggcccga atgtgacatc cggccccacg agggcggatt tcggttaccg
    19081 tccgaacggg tggattgacg aggcgtacga ctgggcatca ccggcgtgcg catcggcggc
    19141 cccctgtccg ctgcgctcac gatcatgggc cgaaggagcg acatgcaggt ctggccgggc
    19201 gagagctacc ccctcggcgc cacctacgac gggatgggca ccaacttcgc gatcttctcc
    19261 gaggtggcgg agaagatcga gctctgcctg ttcgacgagt gggacatcgg caccgagcgc
    19321 cgggtggagc tgcgcgaggt cgacgcgtac gtctggcacg cctacatccc cggcgtcgag
    19381 cccggccagc gctacggata ccgggtgcac gggccgtgga acccggccga ggggctgcgc
    19441 tgcaacccgc acaagctgct gctcgacccg tacgcgaagg cggtcgacgg ggagatcatg
    19501 tggcacccgt cggtctacga ctacgaggtc ggcggcgacc cggaccggat gaacaccgag
    19561 gactcggctc cgtacatgcc gaagtcggtg gtggtgaacc cgtacttcga ctggggcaac
    19621 gaccggccgc cgcgcacccc gtaccaccac tcggtgatct acgaggccca cgtgcgcggg
    19681 ctgaccatgc gccacccggg catcccggag gagctgcgcg gcacgtacgc ggcgatcgcc
    19741 tcgccggtga tgatcgagca cttcaaacgg ctcggcgtga cagcggtgga gctgatgccg
    19801 gtgcacgagt tcgtgcacga ccaccgcctg gccgacctgg ggctgcgcaa ctactggggc
    19861 tacaacacca tcggcttctt cgccccgcac cacggctact ccgcgctggg ccgcctgggc
    19921 cagcaggtgc aggagttccg gggcatggtc aaggcgctgc acgccgccgg catcgaggtc
    19981 atcctcgacg tggtctacaa ccacaccgcc gagggcaacc acctcgggcc gtcgctgagc
    20041 ttcaagggca tcgacacgcc cagctactac cggctctccg aggacgaccg gcgttacttc
    20101 gtcgactaca ccggcaccgg caacagcctc aacgtgcgca gcccgcactc gctgcaactg
    20161 atcatggatt cgctgcgtta ctgggtgacc gagatgcacg tcgacgggtt ccggttcgac
    20221 ctggcggcca cgctggcccg cgagttctac gaggtggacc gcctgtccac cttcttcgag
    20281 gtggtgcagc aggacccggt ggtcggccgg gtgaaactca tcgccgagcc gtgggacgtc
    20341 ggccccggcg gctaccaggt cggcaacttc ccgccgcagt ggaccgagtg gaacggcaag
    20401 taccgcgaca ccgtacgcga cttctggcgc ggcgagccgg ccacgctcgc cgagttcgcc
    20461 tcccgcatct ccggctccgc cgacctctac caggacgacg gccgccgccc gttccacagc
    20521 atcaacttcg tcacctgcca cgacgggttc acgctggccg acctggtctc ctacaacgac
    20581 aagcacaacg aggcgaacgg cgaggacaac cgggacgggg agagccacaa ccggtcctgg
    20641 aactgcggcg tcgaggggga gaccgacgac ccgggcgtac gcgcgctgcg ggcccggcag
    20701 cggcgcaact tcctggccac gctgatgctg tcccagggcg tgccgatgct cggccacggc
    20761 gacgagctgg gccgcaccca gcacggcaac aacaacgcct actgccagga cagtgagatc
    20821 gcctgggtgg actgggaccg ggccgacgac gagctgctgg acttcgtccg ccggctcacc
    20881 gacttccgca accggcacca ggtgttccgc cgccgccggt tcttcaccgg cctgccggtg
    20941 ggcggccggg ccgccggctc cggactgccg gacctggcct ggtacacccc ggacggccgg
    21001 gagatgaccg gcgaggactg gggcaacgac ttcggccgct cggtggccct gttcgtcaac
    21061 ggcgacggca tcggggaacg cggccagtac ggccagcgcc accgggacga ctcgttcctg
    21121 ctgctgttca acgcgcacga cgcgccgctg gacttcacgc tgcccggcga ggagttcggc
    21181 agccggtggg agctggtgat cagcaccgcg gaacccgacc cggagaagac gacactggtc
    21241 gaggcgggcg gcacggtctg cgtgccggac cgctcgctgc tggtcctgga gaggacggcc
    21301 tgaccgatgc ccgacacccc ccgctcgacc taccgggtcc aggtgcgtcc cggcttcgac
    21361 ctggacgcca cggccgagct ggcgggctac ctcgccgcgc tcggcgtcac ccacctctac
    21421 accgcgcccc tgctcaccgc cacgcccggc tccacgcacg gctacgacgt ggtggaccac
    21481 cgcgcggtca acccgcagct cggcggcgag cctgcccggg cccggctggt ccgggcgctg
    21541 cgcgcggccc ggctgggcct ggtcgtggac atcgtgccca accacgccgg cgtcgcccgg
    21601 cccgaggcca acccggcctg gtgggacgtg ctgcggtccg gacgcgactc ggcgtacgcg
    21661 cgctggttcg acatcgactg ggaccggggg cggctgctgc tgccggtgct cgccgacagc
    21721 gccgacgcgc tcgacgacct gaagctcgtc gacggggagc tgcgctacca cgagcaccgg
    21781 ttcccggtcg ccgacggcac cggcgacggc acgccccggc aggtgcacga ccggcagcac
    21841 tacgagctgg tgaactggcg gcgcggcgac gccgagctga cgtaccgccg gttcttcgcc
    21901 gtgtc
//
