LOCUS       NZ_CP118233            21044 bp    DNA     circular CON 13-JUL-2024
DEFINITION  Micromonospora chalcea strain 1K05785M01 chromosome, complete
            genome.
ACCESSION   NZ_CP118233
VERSION     NZ_CP118233.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora chalcea
  ORGANISM  Micromonospora chalcea
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Study on the Growth Characteristics and Drug Resistance Related
            Proteins of Micromonospora chalcea MCCC 1K05785
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6861996)
  AUTHORS   Yu,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-FEB-2023) Tianjin University, Tianjin University,
            Weijinlu Nub92, Tianjin, Tianjin 300072, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAY-2022
            Assembly Method                   :: CLC NGS Cell v. 5.29
            Assembly Name                     :: TJU-micro-1.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 12.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028768405.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 23:01:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,224
            CDSs (total)                      :: 6,161
            Genes (coding)                    :: 6,110
            CDSs (with protein)               :: 6,110
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 51
            CDSs (without protein)            :: 51
            Pseudo Genes (ambiguous residues) :: 0 of 51
            Pseudo Genes (frameshifted)       :: 16 of 51
            Pseudo Genes (incomplete)         :: 40 of 51
            Pseudo Genes (internal stop)      :: 2 of 51
            Pseudo Genes (multiple problems)  :: 7 of 51
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:37:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 779396
            Orig. end                         :: 800440
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP118233.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21044
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="4"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21044
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21044
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11044](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11044)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            787..2409
                     /db_xref="GeneID:91355207"
                     /locus_tag="PVK74_RS03605"
                     /old_locus_tag="PVK74_03605"
     CDS             787..2409
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355207"
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013285835.1"
                     /locus_tag="PVK74_RS03605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_03605"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_043324748.1"
                     /transl_table=11
                     /translation="MSTTGKSRSWRVPRRRVRPLAVASLGATLALGLVACSGGPASTNA
                     VSGGKAGTSIEATLAFTLSSGFDPGNASSAVATAVNQHVFEGLVDLDPITREPYNALAK
                     SDPTPGADGLTYTVTLRDGAKFSDGTPVTAEDVAWSFTRVLKPADPKAPPLMQGFVSFL
                     DSVTAKDAATVEFKLKYPFALFSERISVIKVVPKAKTGDAAAAKAFDTAPIGSGPFKVD
                     SASKESGIKLSKNETYNGPRPAKVETMTWNTTTEASARVSDLQGGRVQAIEAVPYLNVD
                     SLKDKYTIDVKQAFNQVFLMFNNAAAPFSDKRVRQALHYAIDKDAVIKTALNGYGSPAT
                     SYLDEGNKAYQKAATVYDYNPDKAKALLQEAGVTNLSFRLDTTDNSVVKDVAPLVIEQW
                     KKIGVNATLNTVPSSAIYGDIVPKDTFRVLMATGDPSVFGVDTDLLMRWYYFGETWPGQ
                     RYRWSDANRKAMGDLLDKAAQTSDEAARKALWKQALDMVADDAPLYPILHTKVVTAYDP
                     AKLDGFSGASTTGLYFLGTGRTG"
     gene            2511..3467
                     /db_xref="GeneID:91355208"
                     /locus_tag="PVK74_RS03610"
                     /old_locus_tag="PVK74_03610"
     CDS             2511..3467
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355208"
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013285836.1"
                     /locus_tag="PVK74_RS03610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_03610"
                     /product="ABC transporter permease"
                     /protein_id="WP_064446265.1"
                     /transl_table=11
                     /translation="MLTVLNLVARRFLTLIPLVLGITLFVFVIMQFSPIDPALSVLGDQ
                     ATPAQVEAFRAANGLNDPLPLRYLHFLGDLVRGDLGMTFPPSVPVAEKIAMALPLTIQL
                     TALGVVGALVIALALGIPAALYRDRWPDQVIRIVSMAGIATPSFWLALLFIQEFSVRRP
                     IFPTGGYVNPADSVGLWLQSLALPALALAVPVGCSLARIVRTSMVEELDKDYVRTAVGA
                     GLPPRVVIGRNVLRNALVNPLTALGLRIGYLIGGTVVIEAIFSLPGMGTQIMSAVQQND
                     TALAQGTVLTIALCFVLVNLVVDILYLFANPRLRGGH"
     gene            3467..5425
                     /db_xref="GeneID:91355209"
                     /locus_tag="PVK74_RS03615"
                     /old_locus_tag="PVK74_03615"
     CDS             3467..5425
                     /codon_start=1
                     /db_xref="GeneID:91355209"
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013285837.1"
                     /locus_tag="PVK74_RS03615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_03615"
                     /product="dipeptide/oligopeptide/nickel ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="WP_274478172.1"
                     /transl_table=11
                     /translation="MRRSLTTRLSRPGMAFARLGLAARFALGFVALIVVVGVLAPLLLR
                     HDPTQTGLGPALTGPNGDFWFGLDKLGRDVFSRLVAGTRRSLIVGFGAAGIALVLGAIL
                     GALAGSSRTVVDEIIMRCLDVVMAFPTIVLSALLIISFGKNSLLVLVIAIGFVFTPSVA
                     RIVRANVLSQYGEDYVAAERIIGARRPHIFWRHVLRNCAAPILVFVTVMVADAIVFEAS
                     LSFIGGGLAPQEAASSWGSVIAFGKEMVQIGGWWATFFPGLLILLTVLALNVLSEGMSD
                     AWAAPAARRATSTTRGDALEQAQPGTGEVVELPGLAEAAQRLRERARPLPQGKPVLQVS
                     DLSIGFEGRHRGVDIVDGLTFDVRPGEVVGLVGESGSGKSLSVLAVMGLLPQGARVRGE
                     IRFQDTDLLKLNAKGRRALMGREIAMVYQDALSALNPALRVGAQLAQMIRRGGTRSAEE
                     LMRLVGLDPRRTLAAYPHELSGGQRQRVVIAMALSRDPKLIIADEPTTALDVTVQAQVM
                     ALLLELRERLGFALILVSHDLALVSDVCDRVVVMYGGQIVETGVTADVMEAPAHHYARG
                     LLGSVLSLETGAERLTQIRGVVPSPADFPKGCRFSDRCPMATEICRDTAPTMAGTDGHG
                     YACHHPAVTVSEKEPAR"
     gene            5422..6489
                     /db_xref="GeneID:91355210"
                     /locus_tag="PVK74_RS03620"
                     /old_locus_tag="PVK74_03620"
     CDS             5422..6489
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355210"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013285838.1"
                     /locus_tag="PVK74_RS03620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_03620"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_043324745.1"
                     /transl_table=11
                     /translation="MSATAEHRPIAELSDVHVVHAARGGGMFSREKVYALTGADLVIRA
                     GETVGIVGESGCGKSTLAKVLVGLQRPTAGTVSFAGKDVWSMTATERREHIGAGVGMIF
                     QDPATSLNRRMPVRDILRDPLDVHRRGTRQQREQRVTELMALVGLPRSVADVLPSQLSG
                     GQRQRVSIARALALEPGLVIADEPTSALDVSVRAQILNLLLDLKDRLGLAMVLVSHDIQ
                     TVKRVSDRVVTMYLGRIVEQTPADLLPEGGRHPYTRALFSATPGLLSPIEPIPLVGPVP
                     SATRPPSGCPFRTRCWAATDGCAVDMPAPRPAEGAGHEFRCHHPVPAGTANTELVALAT
                     SATGRTTTESVEENL"
     gene            6486..7424
                     /db_xref="GeneID:91355211"
                     /locus_tag="PVK74_RS03625"
                     /old_locus_tag="PVK74_03625"
     CDS             6486..7424
                     /codon_start=1
                     /db_xref="GeneID:91355211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013285839.1"
                     /locus_tag="PVK74_RS03625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_03625"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_069090135.1"
                     /transl_table=11
                     /translation="MTTPAPRFAGVVPPAVTPLTEEGEVDVHSLERLVEWLLDAGVDGI
                     FALGSSGETVFLTDRQRDLALETIVKTAGGAVPVLAGCIEPTTRRVVERAEASTRLGAD
                     GLVVTAPFYAIVGPHEIERHFRAVAAAVELPLLAYDIPVCVHSKLSVDLLTRLAAEGVL
                     AGVKDSSGDDVAFRQLALAIAEHAPERDFSLLTGHEVVVDAMMLAGGSGSVPGLGNVDP
                     AGYVRLHRACVAGDWAAARREQDRLTRLFRIVDAADPATSAGATRGVGAFKTALSLLGV
                     IAGNAVSLPLRPLDDAETGRVRTQLELAGLL"
     gene            7427..8356
                     /db_xref="GeneID:91355212"
                     /locus_tag="PVK74_RS03630"
                     /old_locus_tag="PVK74_03630"
     CDS             7427..8356
                     /codon_start=1
                     /db_xref="GeneID:91355212"
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013477146.1"
                     /locus_tag="PVK74_RS03630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_03630"
                     /product="ROK family protein"
                     /protein_id="WP_274478174.1"
                     /transl_table=11
                     /translation="MPEVSTTGLVAALDIGGTKTTAALVTAAGEVVGRHTAPTPGRSGA
                     AAVLDTAAGLVEKLRADAPGVVRALGVGSAGVIDSGSGLVLSATDVLTGWAGTDLRGDL
                     GRRLGVPVTVVNDVHAHALGEARHGVAAGYDTVLYVAVGTGVGASFVLGDTVLAGAHSA
                     AGHAGHQPSAYAGTLPCTCGGRGHLEAIAAGPALTAEYVRRTGRPVADLRAVAALAAGG
                     DETARDVVRLGGTAVGSAVGGLVNVLDPAAVVIGGGVTGLGEPWWRALRDAVPAETLPG
                     LAGVPVLASTLGPDAPLLGAASLAWKVS"
     gene            8353..9042
                     /db_xref="GeneID:91355213"
                     /locus_tag="PVK74_RS03635"
                     /old_locus_tag="PVK74_03635"
     CDS             8353..9042
                     /EC_number="5.1.3.9"
                     /codon_start=1
                     /db_xref="GeneID:91355213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013477145.1"
                     /locus_tag="PVK74_RS03635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_03635"
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="WP_274478175.1"
                     /transl_table=11
                     /translation="MNALVDQLRHRLVVSCQAYPGEPMRDPDTMRRVALATARGGAAGI
                     RAQGLADIAAIRAAVDLPLIGLWKDGDDDVFITPTLEHALAVADAGAHVVALDGTSRPR
                     PDGRTLAETIAAVHERTGALVMADCSTFDEGIAAAAAGADLVGTTLSGYTAYTTKGDGP
                     DLDLVARLAAAVDVPVVAEGRIHTPEQTAQALRAGAWTVVVGTAITHPSTITGWFASAV
                     REAASCR"
     gene            9033..10004
                     /db_xref="GeneID:91355214"
                     /locus_tag="PVK74_RS03640"
                     /old_locus_tag="PVK74_03640"
     CDS             9033..10004
                     /codon_start=1
                     /db_xref="GeneID:91355214"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013285842.1"
                     /locus_tag="PVK74_RS03640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_03640"
                     /product="acetylxylan esterase"
                     /protein_id="WP_274478178.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 2.6e-06, bitscore:
                     25.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLTDLDLAGCLAYRPELDVPADLDGFWARTLDGGGDPAAAVYEP
                     VDTGLTQIRTYAATIPGFAGEPVRGWLHLPAGADGPLPCVVEYLGYGRGRGLPHEKLFW
                     AAAGFAHLIMDSRGQGWSAATGGTPDPHPYPAGTVPGFLTRGVADPAEHYYRRLITDAV
                     RFAEAARRHPAVDPRRVAVTGFSQGGGLALAVGALCPDVAAVMPDVPFLCDIRRGVRVA
                     GPDSPYAEVVEYLALHRDRADQVFRTLSYLDAAVLAPRATAPALFSIALRDQVCPPSTC
                     FAAYHRYGGDKDVRVYEFNDHEGGEAAHQGEQLTWLRGILGG"
     gene            complement(10001..11044)
                     /db_xref="GeneID:91355215"
                     /locus_tag="PVK74_RS03645"
                     /old_locus_tag="PVK74_03645"
     CDS             complement(10001..11044)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91355215"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013285843.1"
                     /locus_tag="PVK74_RS03645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_03645"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_274478179.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.2e-44, bitscore:
                     151.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATAAGVAGGHVERMLERYRGLALGALLDDVPDGGPRYLYDLVAE
                     YPRRWGKGLRAALCLATCRAFGGGDAVGLNAAVTVELFHNAFLIHDDIQDSSEQRRGGR
                     TLHAEYGVGVALNVGNMTNLLALRRLAANRAALGSGIAWRLFTETELMMRHSLEGQAIE
                     IGWIRDNVCDLDADDYYRMCLKKTSWYTCIYPCRTGILVATGRENAVDVLDRYGWYLGA
                     AFQIQDDALNLTGDYARYGKEIAGDLWEGKRTLILIDFMRRCTPEERERLVRLLSRTRA
                     QRTDAEVRWLHGRLLAYDCVESARRSARDLALAARREGERALGAAADTEDGRFLLELTD
                     YVVERAR"
     gene            complement(11052..11462)
                     /db_xref="GeneID:91355216"
                     /locus_tag="PVK74_RS03650"
                     /old_locus_tag="PVK74_03650"
     CDS             complement(11052..11462)
                     /codon_start=1
                     /db_xref="GeneID:91355216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013477142.1"
                     /locus_tag="PVK74_RS03650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_03650"
                     /product="hypothetical protein"
                     /protein_id="WP_013477142.1"
                     /transl_table=11
                     /translation="MENVERERTNERFEKVAEETSETVTHAATVLEEELAAGLAGARRL
                     EEKLTESRRVDPEAFDELVARVRTDGHALIDTVVGQLKMADDQRGEVIRRYTSDAHDAL
                     DTVLNLARLAPEVANGLADRLASPAPKRPTDR"
     gene            complement(11546..15349)
                     /db_xref="GeneID:91355217"
                     /locus_tag="PVK74_RS03655"
                     /old_locus_tag="PVK74_03655"
     CDS             complement(11546..15349)
                     /codon_start=1
                     /db_xref="GeneID:91355217"
                     /inference="COORDINATES: protein motif:HMM:NF013508.4"
                     /locus_tag="PVK74_RS03655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_03655"
                     /product="hypothetical protein"
                     /protein_id="WP_274478180.1"
                     /transl_table=11
                     /translation="MVHKGWRRPASALAVLAVLASSSMFAVVVSPPPASATVPGQPGVP
                     QPGTPIFTEDFSNESAADAPIRIGSYTGSPGSVYVPGPGGSGADSETYTADPAWSPGAG
                     ACNGWIMRQTSPLPPNGGDPPVTDNDQCARSRAWSTIGQMVHDMGVFQGQSDEEATTNQ
                     AFTEFSNGIGGVQAAGYQFDTDSNTIPAVGGHFYAVSAIFAETNCQVPGAARASERFEL
                     MLNEVPTVLAEGLNPCTDPSAVVINGTYIAKLQSTAIQLPVDDTPTLGLRLYNATATGV
                     GNDVAFDLPQIVDVTPQLDKAFSPATIGQGQTSTLTFTVTNTDDLQAKNGMSFTDELPA
                     GVTATGVNNTTCSDATVTAAAGATSVVFDGDIGLGVASCTVSVEVTADVVGSYTNTGCA
                     GPDGTPIPGCESNFPTILGINPPGSATLQVIPTVDLAVTKTASPNPYVPGTPLTYTVTV
                     TNGGPSDAVGATVTDPLPAPGFTWTCAASTGSTCTASGTGDISDTVTVLGGGTLTYTVS
                     GTVPSSTTGDLTNTATVTPPDGVSDPGCTPTCTATVVTPAAPSVDLAVTKTATPDPYVP
                     GASLTYTVTVTNGGPSDAVGATVTDTPRLPGFTWTCAASTGSTCTASGSGDIADTVTVL
                     AGGTLTYTISGTVPAGTTGDLTNTATVTPPEGVSDPGCTPNCTATVVTPGRPTVDLAVT
                     KTATPNPYVPGTSLTYTVTVTNGGPSDAVGATVTDALPEPLAGFEWTCTAGTGSTCTAS
                     GLGDINDRITVRVGESVVYTITGTVPAGTTGDLTNTATVTPPDGATDPDCTPTCSATVV
                     TPGQPTVDLAVTKTATPNPYVPGAPLTYTVTVTNGGPSDAVGATVTDPLPLPGLTWTCE
                     ASTGSTCAASGSGDIADTVTVLAGGTLSYTITGTVPAGTTGDLRNTTTVTPPEGTTDPD
                     CTPTCSATVVTPGQVTVGLVVTKTATPSPYVPGSPFTYTVTVTNGGPSDAVGATVTDTP
                     RLPGFTWTCAASTGSTCTASGSGDIADTVTVLAGGTLTYTISGTVPAGTTGDLTNTTTV
                     TPPEGTTDPGCTPNCTATVVTPAAPTVDLAVTKTATPNPYVPGTPLTYTVTVTNGGPSD
                     AVGATVTDPLPLPGFTWTCKASTGSTCTASGNGDINDTVTVLAGGTLTYTITGTVPADT
                     TGDLTNTTTVTPPEGATDPDCTPNCSATVVVAGPVQPTPTPPTPEPPTPKPPKPGPHKP
                     IPPLPVTGSGTAVITSIGLAAVALGVLLVAGLVLTRRSRRHP"
     gene            15555..17117
                     /db_xref="GeneID:91355218"
                     /locus_tag="PVK74_RS03660"
                     /old_locus_tag="PVK74_03660"
     CDS             15555..17117
                     /codon_start=1
                     /db_xref="GeneID:91355218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013285845.1"
                     /locus_tag="PVK74_RS03660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_03660"
                     /product="phenylacetate--CoA ligase family protein"
                     /protein_id="WP_274478181.1"
                     /transl_table=11
                     /translation="MAETLHRHAALRTVDTPLPAEAALAPAGRAVAALARLIAHHPAGW
                     RWLARRHHPVLDRLAAANARSTCVRAARRVPAYQAFLRARPGGLRRRLRDFPETDKRGY
                     VMAYDASARCRDGRMPERGVVVDESAGSSGRPFNWPRGERELRAVHRDIAGYTGLAFPM
                     RRPFVINAYSMGAWATGTTTGAAMARIATVKNTGPDLGKIVDTLREFGPGHDYLVTAYP
                     PFLKHLRDRLDAEDFPWSRYRIFASCGGEGMTEALRDYLEQRFVRVRSAYGASDLTIGI
                     GAETRFTVWLRRRLRTDAGLRAELLGRGEQRLPMVFQYNPFATYLETNDRRELLCTVTG
                     PHVLQPRLRYNVGDEALLVPYRRIVELAHADPVRRAEFRTAVAEERMTLPLLLLFGRSD
                     STVSYLGANLYPQDVEYGLYTGNPYAAEINRFCLTLHEDAALETRPVIHVELRRPLDAA
                     ARAALADACRDGVRAHLTSVSRDFAQSLVEDPTAGDLRVELHEPDCGPFAAMQKIKNVY
                     LVR"
     gene            17121..17561
                     /db_xref="GeneID:91355219"
                     /locus_tag="PVK74_RS03665"
                     /old_locus_tag="PVK74_03665"
     CDS             17121..17561
                     /codon_start=1
                     /db_xref="GeneID:91355219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018786877.1"
                     /locus_tag="PVK74_RS03665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_03665"
                     /product="hypothetical protein"
                     /protein_id="WP_064446256.1"
                     /transl_table=11
                     /translation="MRTRDFSRAPAQARAGAMFIGGTRYANPLVLLRLAPDWIRMVRDM
                     RRMSGYCWHTVYWQFPLTLGTIAFFTDRDALLRFARTRHHRKLMMWLTDGNRNATAGFI
                     RLYTASPDGYSNGAWRAEDGAMGHIERFTPLGAETTGPAVRR"
     gene            17558..18640
                     /db_xref="GeneID:91355220"
                     /locus_tag="PVK74_RS03670"
                     /old_locus_tag="PVK74_03670"
     CDS             17558..18640
                     /codon_start=1
                     /db_xref="GeneID:91355220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013477140.1"
                     /locus_tag="PVK74_RS03670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_03670"
                     /product="hypothetical protein"
                     /protein_id="WP_274478182.1"
                     /transl_table=11
                     /translation="MTGHRFERVTGRRGLRDFLALTDRLYADESRYVPTPRQQIRRWWR
                     DGVPMYVLRDASGAVAGRTTLHTDADLDAKLGRRCQLFGLTEFTPHAARPLFDAIATHA
                     TPGRDLLFGPVALLPNQAGGVITSGYADRGFVDSAWNPPHYPDAYEENGFTGRFVSDTW
                     ICPVPPPTGPPPALGVQPDGSRLDLHRGNSRRLDEQLDLLRGMLNDSFAQLGYYTPISA
                     AQLRRQTDGLAYLLDDSLLLYLTRDGHPVAFVLCVPDISDFLVAVRGDLNPVNQLRLLA
                     TRRRYRREAVLIVKGVVPRFQGRGYQRLLSEHLHRNLHEGGYTALRSTYVGRDNPASAA
                     QYRRLGGRPLHGYTFYARER"
     gene            18643..19659
                     /db_xref="GeneID:91355221"
                     /locus_tag="PVK74_RS03675"
                     /old_locus_tag="PVK74_03675"
     CDS             18643..19659
                     /codon_start=1
                     /db_xref="GeneID:91355221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018786879.1"
                     /locus_tag="PVK74_RS03675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PVK74_03675"
                     /product="nitroreductase"
                     /protein_id="WP_166456595.1"
                     /transl_table=11
                     /translation="MDLAAFRALEPLCWRAPSAHNTQPWRLRYERWAITVGWDPADTLP
                     AGDPTGRDLRLSLGAFVETCLIVAADAGLRLDWAADHDESDRRVGRLRPARQPYRTPFR
                     AADVWDRRTHRGRFTGGPDADVVAAVDAVARRAGGAARVVPAAGRLRALLRTADRHVYA
                     DPSVVAELRRWLRLDRACPRYRSDGLSDSCLGLGRAAATGLRAALAAYPALRPLGLPRL
                     LAAAGGDPLAQGGGVLALIAPPGLDAAGQVEFGRVLMRMWLTLHTAGLAAHPLSQLVDV
                     AATRGALGTLLDVAPERIVHVARVGRPAAPAPRSARRVRHGSRLLAVTPLDAMSLHP"
     misc_feature    19618..19620
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    20181..20201
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.0"
                     /tool="antismash"
     misc_feature    20861..20879
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.6"
                     /tool="antismash"
ORIGIN
        1 cggcggtgag ggcggccacg atggcctggt gccgctgggc ggtgatgacc cggtcctccg
       61 gctcggtgcg cagggtcggc gcgacgatgg cctgcacctg ccagaacgcc tcggtcagct
      121 ggaccagcag gtcgttgccg agcggctcca tcagcttcag gtggaaggcc cggtcgacgt
      181 cgaggaagtc ctcgccctgt gccgcccggc tgcgcatctc gtcggcgagc gcggacagct
      241 ccgaccggtg ctcctcgtcc agggcgtcga tgacggtggc cgccagcccc tgctccagcg
      301 tctgccggat gtcgacgacc tgggccagta cgtggtggtc gtcctcgccg ctgagcagcc
      361 ctcggaacgt caggctctcc accagggcgt tgagggacat ccggccgacg aacgtgccgt
      421 ggccgtggcg cacctcgacg atgtcgagcg cggagaggat cttgacggcc tcgcggacgc
      481 tggagcggct ggcgccgacc gcctcgcaca gctccgtctc ggtgggcagg agattgcccg
      541 gcttgaggcg gttgcgcagg atgtactcct tgatcctggt ggcgacctcc tgccggcgag
      601 ggctcggccg ctcggcgccg cgtagcggac tggcgtcaat ggtcgtcatc tgccccttgc
      661 ccttcgttcc cgaatctgac accctcaccc taccggcatc agacgtcaga cgtcatacac
      721 cttacacttc acatccccgg cgcgagcggc gacgcgagcg catgaagagc ctatggaggc
      781 atctacgtga gcaccaccgg taagtcgcgg agctggcgcg tgccgcgccg ccgcgtccgc
      841 cccctggccg tcgcctccct cggagcgacc ctcgccctcg ggctggtggc ctgcagcggc
      901 ggtcccgcct cgaccaacgc ggtcagcggc gggaaggcgg gcacgtcgat cgaggccacc
      961 ctggcgttca cgctctccag cggtttcgac ccgggcaacg cctcctccgc cgtggcgacc
     1021 gccgtcaacc agcacgtctt cgagggtctc gtggacctcg acccgatcac gcgggaaccc
     1081 tacaacgcgc tggccaagag cgacccgacg cccggcgccg acggcctcac gtacaccgtg
     1141 acgctgcgcg acggcgcgaa gttctccgac ggcacccccg tcaccgccga ggacgtcgcc
     1201 tggtcgttca cccgcgtgct gaagccggcg gacccgaagg cgccgccgct gatgcagggc
     1261 ttcgtctcgt tcctcgacag cgtcaccgcc aaggacgcgg ccaccgtcga gttcaagctg
     1321 aagtacccgt tcgccctgtt cagcgagcgg atctcggtca tcaaggtcgt gcccaaggcc
     1381 aagaccggtg acgcggcggc ggccaaggcg ttcgacaccg cgccgatcgg gtccggcccg
     1441 ttcaaggtgg acagcgcgtc caaggaatcc ggcatcaagc tgagcaagaa cgagacctac
     1501 aatggcccgc gcccggccaa ggtcgagacg atgacgtgga acaccaccac cgaggcgtcg
     1561 gcccgggtgt cggacctgca gggcggccgc gtgcaggcca tcgaggccgt gccgtacctg
     1621 aacgtcgact cgctcaagga caagtacacg atcgacgtga agcaggcctt caaccaggtc
     1681 ttcctcatgt tcaacaacgc cgccgcgccg ttcagcgaca agcgcgtccg ccaggccctg
     1741 cactacgcca tcgacaagga cgcggtcatc aagaccgcgc tcaacggcta cggcagcccg
     1801 gcgaccagct acctcgacga gggcaacaag gcgtaccaga aggccgccac cgtctacgac
     1861 tacaacccgg acaaggccaa ggccctgctc caggaggccg gcgtcaccaa cctgtcgttc
     1921 cggctcgaca ccaccgacaa ctcggtggtc aaggacgtcg ccccgctggt catcgagcag
     1981 tggaagaaga tcggcgtcaa cgccacgctc aacaccgtgc cgtcctcggc catctacggc
     2041 gacatcgtcc ccaaggacac gttccgggtg ctcatggcca ccggtgaccc gagcgtcttc
     2101 ggcgtcgaca ccgacctgct gatgcgctgg tactacttcg gcgagacctg gccgggccag
     2161 cgttaccgct ggagcgacgc caaccgcaag gccatgggcg acctgctgga caaggccgcg
     2221 cagacctccg acgaggcggc ccgcaaggcg ctgtggaagc aggccctgga catggtggcg
     2281 gacgacgccc cgctctaccc gatcctgcac accaaggtcg tcaccgcgta cgacccggcc
     2341 aagctcgacg gcttctcggg cgcctcgacc accggcctgt acttcctggg caccggccgg
     2401 accggctgag cccactcggg gctccgcccc cgcctccgtc ccgtccggcc gcacgtgacc
     2461 cgtgcggccg gacgggacgc cccggcgccc cgccacgaga aagagaatcc atgctgaccg
     2521 tcctgaacct ggtcgcacga cgattcctga cgctgatccc cctggtgctg ggcatcacgc
     2581 tcttcgtctt cgtgatcatg cagttctccc cgatcgaccc ggcgctatcc gtcctcggcg
     2641 accaggccac gccggcgcag gtcgaggcgt tccgcgccgc gaacgggctg aacgacccgc
     2701 tgccgctgcg ctacctgcac ttcctcggcg acctcgtccg cggcgacctc ggcatgacgt
     2761 tcccgccgtc ggtcccggtc gccgagaaga tcgccatggc gctgccgctg accatccagc
     2821 tcaccgcgct cggcgtcgtc ggcgcgctgg tcatcgcgct ggccctcggc atcccggccg
     2881 ccctgtaccg ggaccgctgg cccgaccagg tcatccggat cgtctccatg gccggcatcg
     2941 ccacgccgtc gttctggctg gccctgctgt tcatccagga gttctcggtc cgccgcccga
     3001 tcttcccgac cggtggatac gtcaaccccg ccgactcggt cggcctctgg ctgcagtccc
     3061 tcgcgctgcc cgcgctggcg ctggccgtac cggtcggctg ctcgctggcc cgcatcgtcc
     3121 gcacgtcgat ggtcgaggaa ctcgacaagg actacgtccg caccgccgtc ggcgccggac
     3181 tgccaccgcg cgtggtgatc ggccgcaacg tgctgcgcaa cgcgctggtc aacccgctca
     3241 ccgcgctcgg cctgcggatc ggctacctca tcggcggcac cgtcgtcatc gaggccatct
     3301 tctcgctgcc cggcatgggc acccagatca tgagcgccgt ccagcagaac gacaccgcgc
     3361 tcgcccaggg caccgtgctc accatcgcgc tgtgcttcgt cctggtgaac ctggtcgtcg
     3421 acatcctcta cctcttcgcc aacccccgac tgcgcggagg ccactgatgc gccggtccct
     3481 caccacgcgg ctgtcccgcc ccggcatggc cttcgcccgg ctcggtctcg cggcccggtt
     3541 cgcgctcggc ttcgtcgcgc tcatcgtcgt ggtcggcgtg ctcgccccgc tgctgctgcg
     3601 ccacgacccc acccagaccg gcctcggacc ggcgctgacc ggcccgaacg gcgacttctg
     3661 gttcggcctg gacaaactcg gccgcgacgt cttctcccgg ctggtcgccg gcacccggcg
     3721 ctccctgatc gtcggtttcg gcgcggccgg catcgcgctg gtgctcggcg cgatcctcgg
     3781 cgcgctcgcc ggcagcagcc gcaccgtcgt cgacgagatc atcatgcgct gcctcgacgt
     3841 ggtcatggcc ttccccacga tcgtgctctc cgcgctgctg atcatctcgt tcggcaagaa
     3901 cagcctgctg gtcctcgtca tcgcgatcgg gttcgtgttc accccctcgg tcgcgcgcat
     3961 cgtccgcgcc aacgtgctgt cccagtacgg cgaggactac gtggccgccg agcgcatcat
     4021 cggcgcccgc cgcccgcaca tcttctggcg gcacgtcctg cgcaactgcg ccgccccgat
     4081 cctcgtcttc gtcaccgtca tggtggccga cgcgatcgtc ttcgaggcgt ccctgtcctt
     4141 catcggcggc ggcctcgccc cgcaggaggc ggcctcctcg tggggctcgg tcatcgcctt
     4201 cggcaaggag atggtgcaga tcggcggctg gtgggccaca ttcttccccg gcctgctgat
     4261 cctgctcacc gtgctggcgc tcaacgtgct ctccgagggc atgtccgacg cctgggccgc
     4321 cccggccgcg cgccgcgcca cgtccaccac caggggtgac gcgctggagc aggcgcagcc
     4381 cggcaccggc gaggtggtcg agctgcccgg cctggccgag gcggcgcagc ggctgcgtga
     4441 gcgcgcccgc ccgctgccgc agggcaagcc ggtccttcag gtcagcgacc tgtccatcgg
     4501 cttcgagggc cgccaccgcg gcgtcgacat cgtcgacggg ctcaccttcg acgtacgccc
     4561 cggcgaggtc gtcggcctgg tgggggagtc cggctccggc aagtcgctga gcgtcctcgc
     4621 cgtcatgggt ctgctgccgc agggcgcccg ggtacgcggc gagatccgct tccaggacac
     4681 ggacctgctg aaactcaacg ccaagggccg ccgcgccctg atgggccgcg agatcgccat
     4741 ggtctaccag gacgcgctgt cggcgctgaa cccggcgctg cgcgtcggcg cccagctcgc
     4801 ccagatgatc cgccgcggcg gcacccgctc ggccgaggaa ctgatgcggc tggtcgggct
     4861 ggacccgcgg cgcacgctcg ccgcgtaccc gcacgagctg tccggcgggc agcggcagcg
     4921 cgtcgtgatc gccatggcgc tgtcccgcga cccgaagctg atcatcgcgg acgagccgac
     4981 caccgcgcta gacgtcaccg tgcaggccca ggtgatggcg ctgctgctgg agctgcgcga
     5041 gcggctcggc ttcgccctca tcctggtcag ccacgacctc gccctggtca gcgacgtctg
     5101 cgaccgggtc gtggtgatgt acggcgggca gatcgtggag accggcgtga ccgccgacgt
     5161 gatggaggcg cccgcccacc actacgcccg cggcctcctc ggctcggtcc tgtccctgga
     5221 gaccggcgcg gaacggctca cccagatccg cggcgtggtg ccctcaccgg ccgacttccc
     5281 gaagggttgc cggttctccg accgctgccc gatggcgacc gagatctgcc gggacaccgc
     5341 gcccaccatg gcgggcacgg acggccacgg gtacgcctgc caccaccccg ccgtcaccgt
     5401 cagcgagaag gagccggccc gatgagcgcc accgccgagc accggccgat cgccgagctg
     5461 agcgacgtgc acgtggtgca cgccgcgcgc ggcggcggca tgttcagccg ggagaaggtc
     5521 tacgcgctca ccggcgccga cctggtcatc cgggccggcg agacggtcgg catcgtcggc
     5581 gagtccggct gcggcaagtc caccctcgcc aaggtgctcg tcggcctgca acggccgacc
     5641 gccggcacgg tgtccttcgc cggcaaggac gtgtggtcga tgaccgccac cgaacggcgc
     5701 gagcacatcg gcgccggcgt cggcatgatc ttccaggacc cggccacctc actgaaccgc
     5761 cggatgccgg tacgcgacat cctgcgcgac ccgctcgacg tgcaccgccg gggcacccgg
     5821 cagcagcgcg agcagcgggt gaccgagctg atggccctgg tcggcctgcc ccgctcggtc
     5881 gccgacgtgc tgcccagcca gctctccggc ggccagcgcc agcgggtgtc catcgcccgc
     5941 gcgctggccc tggaaccggg gctggtcatc gccgacgaac cgaccagcgc gctcgacgtg
     6001 tcggtccgcg cgcagatcct caacctgctg ctggacctca aggaccggct cggcctggcc
     6061 atggtgctgg tgtcgcacga catccagacc gtcaagcggg tcagcgaccg ggtcgtcacc
     6121 atgtacctgg gccgcatcgt cgagcagacc cccgccgacc tgctgcccga gggcggccgg
     6181 cacccgtaca cccgggcctt gttctcggcc acgccgggcc tgctctcacc gatcgagccc
     6241 attccgctgg tcggcccggt cccgtcggcg acccggccgc cgagcggctg cccgttccgg
     6301 acccgctgct gggccgccac cgacggctgc gccgtggaca tgcccgcgcc gcgccccgcc
     6361 gagggcgcgg gccacgagtt ccgctgccac cacccggtgc ccgccggcac cgccaacacc
     6421 gaactggtcg cgctcgccac ctcggcgacc ggccgcacca caactgagtc tgtcgaggag
     6481 aacctgtgac caccccagcc ccgcggttcg ccggagtcgt gccgccggcc gtcacccccc
     6541 tgaccgaaga gggcgaggtc gacgtccact ccctggaacg gctggtcgag tggctgctcg
     6601 acgccggcgt cgacggcatc ttcgccctcg gcagctccgg cgagacggtc ttcctcaccg
     6661 accggcagcg ggacctcgcg ctggagacca tcgtcaagac cgccggcggc gccgtgccgg
     6721 tcctcgccgg ctgcatcgaa cccaccaccc gccgggtcgt ggagcgggcc gaggcgtcca
     6781 cccggctggg cgcggacggc ctcgtcgtga ccgccccgtt ctacgccatc gtcggcccgc
     6841 acgagatcga gcggcacttc cgcgccgtcg ccgcggcggt cgagcttccg ctgctggcgt
     6901 acgacatccc ggtctgcgtg cacagcaagc tctccgtcga cctgctgacc cgcctcgccg
     6961 ccgagggcgt gctggccggc gtcaaggact ccagcggcga cgacgtcgcg ttccgccagc
     7021 tggcgctcgc catcgccgag cacgcgccgg agcgcgactt cagcctgctc accggccacg
     7081 aggtcgtggt cgacgcgatg atgctcgccg gtggctccgg ctcggtgccc ggactgggca
     7141 acgtggaccc ggccgggtac gtgcggctgc accgcgcctg cgtggccggc gactgggccg
     7201 cggcccggcg ggagcaggac cgcctgaccc ggctgttccg catcgtcgac gcggccgacc
     7261 cggccacctc ggcgggcgcc actcggggcg tcggcgcgtt caagaccgcg ctgtccctgc
     7321 tcggcgtcat cgccggcaac gcggtgtcgc tgccgctgcg gccgctggac gacgccgaga
     7381 cgggccgcgt gcgtacccag ctggaactgg ccgggctgct ctgaccatgc ccgaggtgag
     7441 cacgaccggt ctggtcgccg cgctcgacat cggcggcacc aagaccacag ccgcgctggt
     7501 caccgccgcc ggcgaggtcg tcggccggca caccgcgccg acacccggtc gctccggcgc
     7561 cgcagcggtg ctcgacaccg ccgccggcct ggtcgagaag ctgcgggcgg acgcgccggg
     7621 tgtcgtacgg gcgctcggcg tcggcagcgc cggcgtcatc gacagcggct ccggcctggt
     7681 gctgtccgcc accgacgtgc tgaccgggtg ggccggcacg gacctgcgcg gcgacctggg
     7741 ccggcgcctg ggcgtgccgg tcaccgtggt caacgacgtg cacgcccacg cgctgggcga
     7801 ggcgcgtcac ggcgtcgcgg ccgggtacga cacggtgctc tacgtcgccg tgggcaccgg
     7861 tgtcggcgcg tcgttcgtcc tcggcgacac agtgctcgcc ggtgcgcaca gcgcggccgg
     7921 gcacgccggg caccagccgt cggcgtacgc cggaacgctg ccctgcacct gcggcgggcg
     7981 cgggcacctg gaggcgatcg ccgccgggcc cgcgctcacc gccgagtacg tccggcgtac
     8041 cggccgtccg gtggccgacc tgcgggccgt cgccgcgctc gcggcaggcg gcgacgagac
     8101 ggcccgcgac gtcgtccggc tcggcggcac ggccgtcggg tccgccgtcg gcggcctggt
     8161 caacgtgctc gaccccgccg ccgtggtgat cggcggcggc gtcaccggcc tcggcgagcc
     8221 gtggtggcgg gcgctgcgtg acgcggtgcc cgccgagacg ctgcccggcc tggccggagt
     8281 gccggtcctc gcctccaccc tcggccccga cgcgccgctg ctcggcgccg cctcgctcgc
     8341 ctggaaggtc tcatgaacgc actcgtcgac cagctccgcc accgcctggt ggtctcctgc
     8401 caggcgtacc cgggtgagcc catgcgcgac ccggacacca tgcgccgggt cgcgctcgcc
     8461 accgcccgcg gcggcgccgc cggcatccgc gcgcagggac tggcggacat cgcggccatc
     8521 cgcgcggcgg tggacctgcc gctgatcggg ctctggaagg acggcgacga cgacgtcttc
     8581 atcaccccga cgctcgaaca cgcgctggcc gtcgccgacg ccggggcgca cgtcgtcgcg
     8641 ctcgacggca cgtcccggcc ccgccccgac ggccgcacgc tcgccgagac gatcgcggcc
     8701 gtgcacgagc gcaccggcgc gctggtgatg gccgactgct ccacgttcga cgagggcatc
     8761 gccgccgccg ctgccggcgc cgacctggtc ggcaccacgc tctccgggta caccgcgtac
     8821 accaccaagg gcgacgggcc ggacctggac ctggtcgccc ggctcgccgc cgcggtcgac
     8881 gtcccggtgg tcgccgaggg acgcatccac accccggagc agaccgcgca ggcgctgcgg
     8941 gcgggcgcgt ggacggtggt ggtcggcacc gccatcaccc acccgagcac catcaccggc
     9001 tggttcgcgt ccgccgtacg ggaggccgcg tcgtgccgct gaccgacctc gacctggccg
     9061 gctgcctcgc gtaccggccg gagctggacg tgccggcgga cctggacgga ttctgggcgc
     9121 gcacgctcga cggcggcggc gacccggcgg cggcggtcta cgagccggtc gacaccgggc
     9181 tgacccagat ccggacgtac gcggccacga tccccggttt cgccggtgag ccggtacgcg
     9241 gatggctgca cctgcccgcc ggtgccgacg ggccgctgcc ctgcgtggtc gagtacctcg
     9301 gctacggccg gggccgcggc ctgccgcacg agaagctgtt ctgggcggcg gccggcttcg
     9361 cgcacctgat catggacagc cgcggccagg gctggagcgc cgccaccggc ggcacgcccg
     9421 acccgcaccc ctacccggcc ggcaccgtgc ccggcttcct cacccggggc gtcgccgacc
     9481 cggccgagca ctactaccgg cggctcatca ccgacgcggt acgtttcgcc gaggccgccc
     9541 ggcggcaccc ggccgtcgac ccgcgccggg tggcggtgac cggcttcagc cagggcggcg
     9601 gcctcgccct ggccgtcggc gcgttgtgcc cggacgtcgc cgccgtcatg ccggacgtgc
     9661 cgttcctgtg cgacatccgc cggggcgtgc gcgtcgccgg cccggacagc ccgtacgccg
     9721 aggtcgtcga gtacctcgcg ctgcaccgcg accgcgccga ccaggtgttc cgcacgctgt
     9781 cctacctgga cgccgcagtg ctcgcgccgc gcgccaccgc gccggcgctg ttctccatcg
     9841 ccctgcgtga tcaggtctgc ccgccgtcga cctgcttcgc cgcctaccac cgctacggcg
     9901 gcgacaagga cgtgcgggtg tacgagttca acgaccacga gggcggcgag gcggcacacc
     9961 agggcgaaca gctcacctgg ctgcgcggga tcctgggcgg ctaacgggcc cgttccacca
    10021 cgtagtcggt cagctccagc aggaaacggc cgtcctcggt gtcggcggcg gcgcccagcg
    10081 cccgctcacc ctcacgccgg gccgcgagcg cgagatcccg ggcgctgcgc cgcgccgact
    10141 ccacacagtc gtacgcgagc agccgcccgt gcagccagcg cacctcggcg tcggtgcgct
    10201 gcgcgcgggt acggctcagc aaccgcacga gccgttcacg ttcctccggt gtgcaccgcc
    10261 gcatgaagtc gatcaggatc agcgtgcgct tgccctccca caggtcaccg gcgatctcct
    10321 tgccgtaccg ggcgtagtcg ccggtcaggt tgagcgcgtc gtcctggatc tggaacgccg
    10381 cacccagata ccagccgtac cgatccagca cgtcgacagc gttctcccgg ccggtcgcca
    10441 cgaggatccc ggtgcggcac gggtagatgc acgtgtacca ggacgtcttc ttcaggcaca
    10501 tccggtagta gtcgtcggcg tccaggtcgc acacgttgtc gcggatccag ccgatctcga
    10561 tcgcctgccc ctccagcgag tggcgcatca tcagctcggt ctcggtgaac agccgccagg
    10621 cgatcccgga gccgagcgcc gcccggttcg cggccagccg ccgcaacgcc agcaggttcg
    10681 tcatgttgcc gacgttcagc gccacgccca cgccgtactc ggcgtgcagc gtccgcccgc
    10741 cgcgccgctg ctcgctggaa tcctggatgt cgtcatggat gaggaaggcg ttgtggaaca
    10801 gctccactgt caccgcggcg ttgaggccca ccgcgtcgcc gccgccgaac gcccggcacg
    10861 tggccaggca cagcgcggcg cgcagcccct tgccccaccg gcgcggatac tccgcgacca
    10921 ggtcgtagag gtagcgcggg ccgccgtcgg gcacgtcgtc gagcagcgcg ccgagggcca
    10981 gcccgcgata gcgctccagc atccgttcca cgtgcccgcc ggccaccccg gcggccgtcg
    11041 ccatcgcgcg gctaccggtc cgtcggccgc ttcggggccg gcgacgccag ccggtccgcg
    11101 agcccgtttg ccacctcggg cgccagccgc gccagattga gtacggtgtc cagcgcgtcg
    11161 tgcgcgtccg acgtgtaccg ccggatcacc tcaccgcgct ggtcgtcggc catcttcagc
    11221 tgcccgacca cggtgtcgat cagggcgtgc ccgtcggtgc ggacccgcgc gacgagttcg
    11281 tcgaacgcct ccgggtccac gcgccggctc tcggtcagct tctcctcgag ccgccgggcg
    11341 ccggccagcc ccgccgcgag ttcctcctcc aggaccgtgg ccgcgtgggt cacggtctcc
    11401 gaggtctcct cggccacctt ctcgaagcgc tcgttcgtgc gctcacgctc cacgttctcc
    11461 atgcggcgga gtctccaccc ggctccggcc gacgggctag gcatgtgtcg cgatggtgac
    11521 tgacggtaat gaccgcaggt gggggtcagg ggtgtcggcg cgagcgccgg gtcaggacca
    11581 gaccggcgac caggagtacg ccgagggcca cggcggcgag cccgatcgag gtgatgaccg
    11641 ccgtgccact gccggtcacc ggcaacggcg ggatcggctt gtgcggcccc ggcttgggcg
    11701 gcttcggtgt gggcggttcc ggtgtcggcg gtgtcggggt gggctgcacc ggcccggcga
    11761 cgaccacggt cgccgagcag ttcggcgtac agtccgggtc ggtggcgcct tcgggtggtg
    11821 tgacggtggt ggtgttcgtg aggtctccgg tggtgtctgc gggcacggtt ccggtgatcg
    11881 tgtaggtgag cgtgccgccc gcgaggacgg tgacggtgtc gttgatgtcc ccgttgcccg
    11941 aggcggtgca ggtgctgccg gtggacgcct tacacgtcca ggtgaagccg ggcagcggca
    12001 gcgggtcggt gactgtggcg ccgacggcgt cggacggccc gccgttggtg acggtgaccg
    12061 tgtaggtcag gggagtaccc ggcacgtacg ggttcggcgt ggccgtcttg gtgaccgcca
    12121 ggtcgacggt cggagccgcc ggggtcacca cggtcgctgt gcagttcggt gtgcagccgg
    12181 gatcggtcgt gccctcgggc ggggtgacgg tggtggtgtt ggtgaggtct ccggtggtgc
    12241 ctgcgggtac ggtcccgctg atcgtgtagg tgagcgtgcc gccggcgagc acggtgacgg
    12301 tgtcggcgat gtccccgctg cccgacgcgg tgcacgtgct gccggtggac gccgcgcagg
    12361 tccaggtgaa gccgggcagc cggggcgtgt ccgtgactgt ggcgccgacg gcgtcggacg
    12421 gcccgccgtt ggtgacggtg accgtgtacg tgaacggact tcccggcaca tacgggctgg
    12481 gcgtcgccgt cttcgtcacc acgaggccga ctgtgacctg gccgggggtg acgacggtgg
    12541 ccgagcaggt cggggtgcag tcggggtcgg tggtgccttc cggtggcgtg acggtggtgg
    12601 tgtttctcag gtctcctgtg gtgccggcgg gcacggttcc ggtgatcgtg taggagagcg
    12661 tgccgcccgc gagcacggtg acggtgtcgg cgatgtcccc gctgcccgac gcggcgcacg
    12721 tgctgccggt ggacgcctca caggtccagg tcaggccggg cagcggcagc gggtcggtga
    12781 ctgtggcgcc gacggcgtcg gacgggccgc cgttggtgac ggtgaccgtg taggtcaggg
    12841 gagcacccgg cacgtacggg ttcggcgtcg ccgtcttggt caccgccagg tcaacggtgg
    12901 gctggccggg agtcacgacg gtggccgagc aggtcggggt gcagtcgggg tcggtggcgc
    12961 cgtccggcgg cgtgacggtg gcggtgttcg tgaggtctcc cgtggtcccc gccgggaccg
    13021 ttccggtgat ggtgtagacg accgactcac cgacccggac ggtgatccgg tcgttgatgt
    13081 ctccgagccc ggaggcggtg caggtgctgc cggtgccggc tgtgcacgtc cactcgaacc
    13141 cggccaacgg ctcgggcagc gcgtcggtca ccgtggcgcc gacggcgtcg gagggcccgc
    13201 cgttggtgac ggtgacggtg tacgtcaggg aagtacccgg cacgtacggg ttcggcgtgg
    13261 ccgtcttggt caccgccagg tcgacggtcg gccggcccgg ggtcacgacc gtcgccgtgc
    13321 agttcggcgt gcagccggga tcggagacac cctcgggcgg ggtgacggtg gcggtgttgg
    13381 tgaggtctcc ggtggtgcct gcgggcacgg tcccgctgat cgtgtaggtg agcgtgccgc
    13441 cggcgagcac ggtgacggtg tcggcgatgt ccccgctgcc cgacgcggtg cacgtgctgc
    13501 cggtggacgc cgcgcaggtc caggtgaagc cgggcagccg gggcgtgtcc gtgactgtgg
    13561 cgccgacggc gtcggacggc ccgccgttgg tgacggtgac cgtgtacgtc agcgacgccc
    13621 ccggcacgta cgggtcaggg gttgccgtct tggtgacggc caggtcgacg gagggtgccg
    13681 ccggggtcac caccgtcgcg gtgcaggtgg gcgtgcagcc ggggtcggag accccgtcgg
    13741 gtggggtgac cgtcgcggtg ttcgtgaggt cgccggtggt gctcgacggc acggtcccgc
    13801 tgaccgtgta cgtgagcgtc ccgcccccga gcacggtcac ggtgtcgctg atgtccccgg
    13861 tgccggaggc ggtgcacgtg ctgccggtgg acgccgcgca ggtccaggtg aatccgggcg
    13921 ccggcagggg atcggtcaca gtggcgccga cggcgtcgga cggcccgccg ttggtgaccg
    13981 tgacggtgta cgtcagcggt gtgcccggca cgtacgggtt cgggctcgcc gtcttcgtca
    14041 cggccaggtc gacggtgggg atgacctgga gcgtggcgga gccgggcggg ttgatcccga
    14101 ggatcgtcgg gaagttgctc tcacagccgg ggatcggcgt gccgtccggc ccggcgcatc
    14161 cggtgttcgt gtacgagccg accacgtccg cggtcacctc gacggagacg gtgcaggacg
    14221 cgacgcccag gccgatgtcg ccgtcgaaga ccacggaggt cgcgccggct gccgcggtca
    14281 ccgtggcgtc cgagcaggtg gtgttgttca ccccggtcgc ggtcacgcct gcgggaagct
    14341 cgtcggtgaa gctcatcccg ttcttggcct gcaggtcgtc ggtgttggtg acggtgaacg
    14401 tcagggtgga cgtctgcccc tgcccgatgg tggccgggct gaacgccttg tccagttgcg
    14461 gggtcacgtc gacgatctgg gggaggtcga acgccacgtc gttgccgacg cccgtggcgg
    14521 tggcgttgta gagacgcagg cccagcgtcg gggtgtcgtc gaccgggagt tggatcgccg
    14581 tggactggag cttcgcgatg taggtgccgt tgatcaccac cgcgctggga tccgtgcagg
    14641 ggttgagacc ctcggcgagg accgtcggca cctcgttgag catcagctcg aaccgctcgc
    14701 tggcccgcgc cgcacccggg acctggcagt tcgtctccgc gaagatcgcc gagacggcgt
    14761 agaagtggcc gccgaccgcc gggatggtgt tgctgtcggt gtcgaactgg tagccggcgg
    14821 cctgcactcc gccgatcccg ttggagaact cggtgaaggc ctggttcgtc gtcgcctcct
    14881 cgtcactctg gccctggaag acccccatgt cgtggaccat ctggccgatc gtgctccagg
    14941 cgcggctgcg ggcgcactgg tcgttgtcgg tcacgggcgg gtcgccgccg ttgggcggga
    15001 gcggtgacgt ctgccgcatg atccagccgt tgcaggctcc ggcgccgggg ctccacgccg
    15061 ggtcagccgt gtacgtctcg ctgtccgcgc cgctgcctcc cggccccggc acgtacaccg
    15121 aaccgggtga tccggtgtag gagccgatgc ggatcggcgc gtcggccgcg ctctcgttgg
    15181 agaagtcctc ggtgaagatg ggagtgccgg gttggggcac tcccggctgg ccggggacgg
    15241 tggccgaggc gggcgggggc gagaccacca ccgcgaacat cgacgacgac gccagcacgg
    15301 cgagcaccgc cagcgccgac gcaggtcgcc gccatccctt gtgaaccatc ttcctcttcc
    15361 cccgttgtgg ctggtcggag ccggaaggcc tcgacgctca cagcggtaaa ggtgccaggt
    15421 cattgcctct taagtccgtc ttttcatgat tcctgcgtcc ggtcacggcg gtcggccggc
    15481 tgggtacggg tactcagcgc agtaccgtcc cgtcgctcat gtgtccgcgt cgcggcgtcg
    15541 acaggatcct tgtcatggcc gagacgctgc accgacacgc cgccttgcgt accgtcgaca
    15601 cgccgctgcc cgccgaggcc gcgctggccc ccgccggccg cgcggtcgcc gcgctggccc
    15661 ggctcatcgc ccaccacccc gccggctgga ggtggctggc ccggcgccac cacccggtcc
    15721 tcgaccggct cgccgccgcg aacgcgcggt ccacctgcgt ccgcgccgcc cggcgggtgc
    15781 ccgcgtacca ggcgttcctg cgggcccgcc cgggcgggct gcgccgccgg ctgcgggact
    15841 tcccggagac cgacaaacgt gggtacgtca tggcgtacga cgcctcggcc cggtgccggg
    15901 acgggcggat gccggagcgg ggcgtggtgg tcgacgagtc ggccggctcg tccgggcggc
    15961 cgttcaactg gccgcgcggc gagcgggagc tgcgggcggt gcaccgcgac atcgccgggt
    16021 acaccgggct ggcgttcccg atgcgccgac cgttcgtcat caacgcgtac tcgatgggcg
    16081 cctgggcgac cggcaccacg accggcgcgg cgatggcccg gatcgcgacg gtgaagaaca
    16141 ccggccccga cctggggaag atcgtcgaca cgctgcgcga gttcggcccc ggccacgact
    16201 acctggtgac cgcgtacccg ccgttcctca agcacctgcg ggaccggctc gacgccgagg
    16261 actttccgtg gtcgcggtac cggatcttcg ccagttgcgg cggtgagggg atgaccgagg
    16321 cgttgcgcga ctacctggag cagcggttcg tgcgggtgcg gtcggcgtac ggggcgtcgg
    16381 acctgaccat cggcatcggc gcggagaccc ggttcacggt ctggttgcgg cggcggctgc
    16441 gcaccgacgc gggactgcgc gcggaactgc tgggccgcgg cgagcagcgg ctgccgatgg
    16501 tgttccagta caacccgttc gccacctacc tggagaccaa cgaccggcgg gagctgctct
    16561 gcactgtcac cggcccgcac gtgctccagc cccggctgcg ctacaacgtc ggcgacgagg
    16621 cgctgctggt gccgtaccgg cggatcgtcg aactggcgca cgccgacccg gtgcgccgcg
    16681 ccgagttccg caccgcggtg gccgaggagc ggatgacgct gccgctgctg ctgttgttcg
    16741 gccgcagcga ctccaccgtg tcctacctgg gcgcgaacct ctacccgcag gacgtcgagt
    16801 acggcctcta caccggcaac ccgtacgccg ccgagatcaa caggttctgc ctgacgctgc
    16861 acgaggacgc ggcgctggag acccggccgg tgatccacgt ggagctgcgc cgcccgctgg
    16921 acgccgcggc ccgcgcagcg ctcgccgacg cctgccgcga cggggtacgc gcgcacctga
    16981 cctcggtgtc gcgggacttc gcgcagtccc tggtggagga cccgaccgcc ggtgacctgc
    17041 gggtggaact gcacgaaccg gactgcggcc cgttcgccgc catgcagaag atcaagaacg
    17101 tctacctggt gaggtgagcg atgcgtaccc gtgacttctc ccgcgccccg gcccaggccc
    17161 gcgccggcgc catgttcatc ggcggcaccc ggtacgcgaa cccgctggtg ctgctgcgcc
    17221 tggcccccga ctggatccgg atggtgcgcg acatgcgccg gatgtccggc tactgctggc
    17281 acaccgtcta ctggcagttc ccgctgacgc tcggcaccat cgcgttcttc accgaccgcg
    17341 acgcgctgct gcgcttcgcc cggacccggc accaccgcaa gctgatgatg tggctgaccg
    17401 acggcaaccg caacgccacg gccgggttca tccgcctcta caccgcctcc ccggacggct
    17461 actcaaacgg cgcgtggcgg gccgaggacg gcgcgatggg ccacatcgag cggttcacgc
    17521 cgctgggcgc ggagaccacc ggaccggcgg tgcgccggtg accggccacc ggttcgagcg
    17581 cgtgaccggc cggcgcggcc tgcgcgactt cctcgcgctc accgaccggc tgtacgcgga
    17641 cgagtcccgc tacgtgccga cgccccggca gcagatccgc cgctggtggc gcgacggcgt
    17701 gccgatgtac gtgctgcgcg acgcctccgg cgcggtggcc gggcggacca cgctgcacac
    17761 cgacgccgac ctcgacgcca agctcggccg ccggtgccag ttgttcgggc tcaccgagtt
    17821 cacgccgcac gccgcccggc cgctgttcga cgcgatcgcc acgcacgcca cacccgggcg
    17881 ggacctgctg ttcgggccgg tggcgctgct gcccaaccag gccggcggcg tgatcacctc
    17941 cgggtacgcc gaccggggtt tcgtggacag cgcgtggaac ccgccgcact acccggacgc
    18001 gtacgaggag aacgggttca ccgggcggtt cgtctccgac acctggatct gcccggtgcc
    18061 gccgccgacc gggccgccgc ccgcgctggg cgtccagccc gacggctccc ggctggacct
    18121 gcaccgcggg aacagccggc ggctcgacga acagctcgac ctgctgcgcg ggatgctcaa
    18181 cgactccttc gcccagctcg gctactacac gccgatctcg gcggcgcagc tgcggcggca
    18241 gaccgacggg ctggcgtacc tgctggatga ctcgctgctg ctctacctga cccgcgacgg
    18301 gcacccggtg gcgttcgtgc tctgcgtgcc cgacatcagc gacttcctgg tcgctgtgcg
    18361 cggcgacctg aacccggtca accagctgcg gctgctggcc acccgccgcc ggtaccggcg
    18421 ggaggcggtg ctgatcgtca agggcgtggt gccgcggttc caggggcgcg gctaccagcg
    18481 gctgctgtcc gagcatctgc accgcaacct gcacgagggc ggatacacgg cgctgcgcag
    18541 cacgtacgtc gggcgggaca acccggcgtc ggccgcccag taccggcgcc tcggcggacg
    18601 cccgctgcac ggctacacgt tctacgccag ggagcggtga gcatggacct cgccgcgttc
    18661 cgcgcgctgg agccgctgtg ctggcgggcc ccgagcgcgc acaacaccca gccgtggcgg
    18721 ctgcgctacg agcgctgggc gatcaccgtc ggctgggacc cggccgacac gctgcccgcc
    18781 ggcgacccga ccgggcggga cctgcggctg tcgctcggcg cgttcgtgga gacctgcctg
    18841 atcgtcgccg ccgacgcggg gctgcggctg gactgggccg ccgaccacga cgagtcggac
    18901 cggcgggtgg ggcggctgcg tccggcccgg cagccgtacc ggacgccgtt tcgcgccgcc
    18961 gacgtgtggg accggcgtac ccaccggggc cggttcaccg gcggcccgga cgccgacgtg
    19021 gtcgcggccg tggacgcggt cgcccgccgg gccggtggcg cggcccgcgt ggtgccggcg
    19081 gccgggcggc tgcgcgcgct gctgcgcacg gccgaccggc acgtgtacgc cgacccgtcg
    19141 gtggtcgccg agctgcgccg ctggctgcgc ctggaccggg cgtgcccgcg ctaccggagc
    19201 gacgggctca gtgacagctg cctcgggctg ggccgggcgg cggccaccgg actgcgggcg
    19261 gcgctcgcgg cgtacccggc gttgcgcccg ctggggctcc cccggctgct cgccgccgcg
    19321 ggcggtgatc cactggcgca gggcggcggg gtgctggcgc tgatcgcgcc gcccggtctg
    19381 gacgcggccg ggcaggtcga gttcggacgc gtgctgatgc ggatgtggct gacgctgcac
    19441 acggccgggc tggccgcgca cccgctcagt cagctcgtcg acgtcgcagc cacccgtggc
    19501 gcgctcggca cgctgctgga cgtggcgccg gagcggatcg tgcacgtggc ccgggtgggc
    19561 cggccggccg cgcccgcgcc ccgctcggcc cggcgagtgc gccacggatc gcgtctgtta
    19621 gcggtaacac cccttgacgc gatgtcactt catccatgag agtccatgtt ggccgacgtg
    19681 tcgcccggtc gggagccctg ggcgcggagt ggcaggaacg cggcgtccgg gtgtgcgagg
    19741 cgcaatctgt tagcgataac agagcagccg cgcacccgga cccgcctctg atccgcgcgg
    19801 ttgggagaaa agcatgtctg aagtgacacg acgcaacgtc atcaaggccg cagcggccgg
    19861 caccggcgcc gcgctggtgc cggccgcctg gagcgccgcc gcccgcgccg gctcggcggc
    19921 gcccgcgcag gcgctggccg cgaacgacct ggcgctctgg tacgacgaac cggccggcac
    19981 cgactggctg cgcgccctgc cgatcggcaa cgggcggctc ggcgcgatgg tgttcggcaa
    20041 cgtggacacc gaacggctcc agctcaacga ggacaccgtc tgggccggcg gcccgtacga
    20101 ctcggcgaac acccggggcg cggccaacct ggccgagatc cggcgtcgcg tcttcgccga
    20161 ccagtggacc tcggcccagg atctgatcaa ccagaccatg atgggcagcc ccggcggtca
    20221 gctcgcctac cagaccgtcg gcgacctgcg gctctccttc gggtcggcga gcggggcgac
    20281 gcagtacaac cggacgctgg acctcaccac cgccaccgtc accaccacat acgtgctgaa
    20341 cggtgtccgg taccagcggg aggtgttcgc cagcgcgccc gaccaggtga tagtgctccg
    20401 gctgaccgcc gaccgggcga acgcgatcac gttctccgcc gcgttcgaca gcccgcagcg
    20461 gaccaccgtg tccagcccgg acggcgcgac agtcgcgctc gacggcatct ccggctcgat
    20521 ggagggggtc aacggctcgg tgcggttcct cgcgctggcc aacgccgccg tcaccggcgg
    20581 cacggtgagc agctccggcg gcacgctgcg ggtgtccggc gcgaccagcg tgacggtcct
    20641 gatctcgatc ggcaccagct acgtcaacta ccgcaccgtc aacggcgact accagggcat
    20701 cgcccgcaac cggctgaacg ccgccaagag cgtcgacgtc gaccagctcc gcacccgcca
    20761 ccgcgccgac taccaggcgc tgttcgaccg ggtcacgatc gacctgggcc gcaccgccgc
    20821 cgccgaccag cccaccgacg tacggatcgc gcagcacgcg aacacgaacg acccgcagtt
    20881 cgccgcgctg ctgttccagt tcgggcggta cctgctgatc tcctcgtcgc ggccgggcac
    20941 ccagccggcg aacctgcagg gcatctggaa cgactcgctc acgccgtcct gggactcgaa
    21001 gtacacggtc aacgccaacc tgccgatgaa ctactggccg gccg
//
