LOCUS       NZ_CP094483            22027 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces murinus strain JS029 chromosome.
ACCESSION   NZ_CP094483
VERSION     NZ_CP094483.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces murinus
  ORGANISM  Streptomyces murinus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Draft genome sequence of Streptomyces sp. JS029
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAR-2022) Agricultural Life Science, Sunchon National
            University, Jungangro 255, Suncheon, Jeonnam 57922, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-MAR-2021
            Assembly Method                   :: Unicycler v. 0.3.1
            Assembly Name                     :: JS029
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 164.82x
            Sequencing Technology             :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028753175.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 03:30:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,582
            CDSs (total)                      :: 7,481
            Genes (coding)                    :: 7,273
            CDSs (with protein)               :: 7,273
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 215
            CDSs (without protein)            :: 208
            Pseudo Genes (ambiguous residues) :: 0 of 215
            Pseudo Genes (frameshifted)       :: 110 of 215
            Pseudo Genes (incomplete)         :: 125 of 215
            Pseudo Genes (internal stop)      :: 20 of 215
            Pseudo Genes (multiple problems)  :: 41 of 215
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:08:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8281595
            Orig. end                         :: 8303622
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP094483.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from National Institute of
            Biological Resources.
FEATURES             Location/Qualifiers
     region          1..22027
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="35"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22027
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22027
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:13109](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13109)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(1168..1854)
                     /locus_tag="ME763_RS36655"
                     /old_locus_tag="ME763_36645"
     CDS             complement(1168..1854)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS36655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ME763_36645"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_085563723.1"
                     /transl_table=11
                     /translation="MARTGGRPRQIEPADIVRVGRELGLRNLSLNAVAARLGVSSAALY
                     RHVDGRWGLERLVGESLLAELDLRDDPSDGPVPHLLSTALQLRAFMLRHPGLTGYVQTL
                     FPRGEGGRRLLATAAESLTRRGYSTEAGIVLSAAVASVVIGYTATEETQRERAEELDAQ
                     RRGVEQALLADARLGAAHRALPTITPDEYVRMWLGAAIRGFVEAAPPGRPLHEIRAALL
                     AAGEGQ"
     misc_feature    complement(1892..1910)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 29.19"
                     /tool="antismash"
     gene            complement(2093..2665)
                     /locus_tag="ME763_RS36660"
                     /old_locus_tag="ME763_36650"
     CDS             complement(2093..2665)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS36660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ME763_36650"
                     /product="hypothetical protein"
                     /protein_id="WP_197697376.1"
                     /transl_table=11
                     /translation="MPEQPTLADFFRRRLALDPFTTRHMMQSARKAREQGADDKVVLAC
                     LLHDISVAGLLRSQHGHWGAQLVGPYVDEEVAWAIRQHEILRYFPDESVGYGYPEAYSD
                     FFGAEYQPPAHTRAAYLEARRHRWYMSARMVTINDLYTFDPDVHVEFEEFEDVVGRHFR
                     QPAEGLGFDSSPVAHMWRTMIWPNNFL"
     gene            3229..4058
                     /locus_tag="ME763_RS36665"
                     /old_locus_tag="ME763_36655"
     CDS             join(3229..3568,3568..4058)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612145.1"
                     /locus_tag="ME763_RS36665"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="ME763_36655"
                     /product="IS5 family transposase"
                     /protein_id="WP_274506847.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MRRHELSDAEWEFVRPLLPESLRGRKRLDDRRVLNGIVWKFRTGT
                     AWRDVPERYGPWATLHTRFRRWAADGTFDRMLRAAQAGADAAGDVEWLVSVDSTIVRAH
                     QHAAGARKGGILDPALGRSRGGLTSKIHLACDGRGRPLAFVVTGGNTNDCTRFTAVMEA
                     IRVPRLGPGRPRIRPDHVLGDKGYSSKAIRAWLRRHGIPHTIPERADQVRNRARRGSRG
                     GRPPAFDREAYKHRNVVERCFNRLKQWRGIATRYDKTAQSYEAAVALASLLMWA"
     misc_feature    4060..4073
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.45"
                     /tool="antismash"
     gene            4126..5271
                     /locus_tag="ME763_RS36670"
                     /old_locus_tag="ME763_36660"
     CDS             4126..5271
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="ME763_RS36670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_36660"
                     /product="MFS transporter"
                     /protein_id="WP_085563897.1"
                     /transl_table=11
                     /translation="MSVGAGMSAANTYYVQPLLDTLGHDFGVGSGIAGLVTTFAQVGYV
                     LGLALIVPLGDLVERRRLVTITTAVTGLGLLGMAAAPNIAVLMALAAVVGFCTVTAQIF
                     VPFAAHLATPMNRGRSVGIVMSGLLIGILLARTVSGVIAGATSWRVVYLVAAVLTFALS
                     VACRMELPSSAPTTRTAYHRLLGSVARIYLDEPALRRRGLYGALVFASFSTFWTAIAFQ
                     MADQYHFSQTVIGLFGLLGVAGAGCAQVAGRIADAGWGRVATAGFILLTAVSWIAGWAG
                     GSRIGWLVAGIVVLDLGVQGTHISNQSEVYRLRPEARSRLTTGYMCTYFVGGVTGSALA
                     GAVYGAYGWKGVCLLGAVFPTLALLVWLTEARWPLRTMARG"
     gene            complement(5425..6177)
                     /locus_tag="ME763_RS36675"
                     /old_locus_tag="ME763_36665"
     CDS             complement(5425..6177)
                     /NRPS_PKS="Domain: PKS_KR (8-167). E-value: 1.7e-13. Score:
                     42.8. Matches aSDomain:
                     nrpspksdomains_ME763_RS36675_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152082.1"
                     /locus_tag="ME763_RS36675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_36665"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_085563725.1"
                     /sec_met_domain="adh_short (E-value: 2.6e-36, bitscore:
                     124.0, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 8.3e-41, bitscore:
                     139.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGQLDNKIALVTGASTGIGLGIAERFVKEGATVYITGRRESELKA
                     AAEQLGDRAVPVRGDVSDLDDIDRLFAEIQDRSGRLDVLVANAGGGELARLGNITEEDY
                     DRTFAINVKGIVFTAQKALPLLDRGGSVILLSSTNASKGVPAMSVYSATKAAIRSLARS
                     WAAELAERGIRVNAVSPGPIETPGILGLAGDNPAARRRLTDGFTAQVPLGRMGRPDEVA
                     ALALFLAGDESSFSTGGEFFVDGGLAQI"
     aSDomain        complement(5677..6153)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ME763_RS36675_PKS_KR.1"
                     /evalue="1.70E-13"
                     /label="ME763_RS36675_PKS_KR.1"
                     /locus_tag="ME763_RS36675"
                     /protein_end="167"
                     /protein_start="8"
                     /score="42.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGASTGIGLGIAERFVKEGATVYITGRRESELKAAAEQLGDR
                     AVPVRGDVSDLDDIDRLFAEIQDRSGRLDVLVANAGGGELARLGNITEEDYDRTFAINV
                     KGIVFTAQKALPLLDRGGSVILLSSTNASKGVPAMSVYSATKAAIRSLARSWAAE"
     CDS_motif       complement(6064..6150)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ME763_RS36675_0001"
                     /evalue="1.10E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="ME763_RS36675"
                     /protein_end="38"
                     /protein_start="9"
                     /score="11.7"
                     /tool="antismash"
                     /translation="LVTGASTGIGLGIAERFVKEGATVYITGR"
     gene            complement(6273..6704)
                     /locus_tag="ME763_RS36680"
                     /old_locus_tag="ME763_36670"
     CDS             complement(6273..6704)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018559379.1"
                     /locus_tag="ME763_RS36680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_36670"
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_085563726.1"
                     /transl_table=11
                     /translation="MSANSRLTVATHVLVWMELYRRQGGTVATSEQISESVNTNPVVVR
                     RLLGDLRRAGLVSSRRGAGAGWVLARDPARIGLLEVYDAVESGPLFAMHRTPPNQECPV
                     GRGIQPAIGKIYDRAEAAVRQELAASTLADVLRGVLAAR"
     gene            complement(6847..7698)
                     /locus_tag="ME763_RS36685"
                     /old_locus_tag="ME763_36675"
     CDS             complement(6847..7698)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (22-193). E-value:
                     5.9e-27. Score: 86.8. Matches aSDomain:
                     nrpspksdomains_ME763_RS36685_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006140429.1"
                     /locus_tag="ME763_RS36685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_36675"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_085563727.1"
                     /sec_met_domain="PF00561 (E-value: 2.2e-20, bitscore: 72.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.8e-17, bitscore:
                     62.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPELRRIPVNGVELNVALAGSGPAVLLLHGFPHTWELWTDIMADL
                     SDRYRVIAPDLRGFGASGGTDSGHDAGTLADDAAALLTTLGVSPAAVVGIDAGAPPAFL
                     LALRHPGLVRRLVVMESLLGRLPGAEDFLADGPPWWFGFHSAEPGLAETVLQGQEAAYI
                     DWFLRTGTLGDGVSPTVRDAFVRAYTGRDALSRAFSYYRALPESALQIEQATTDARLTV
                     PTMALGARPVGSALERQLRPVADDLVGHVIEDCGHIIPLHRPHALLTLLRPFLAGEDGV
                     AA"
     aSDomain        complement(7120..7632)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ME763_RS36685_Abhydrolase_1.1"
                     /evalue="5.90E-27"
                     /label="ME763_RS36685_Abhydrolase_1.1"
                     /locus_tag="ME763_RS36685"
                     /protein_end="193"
                     /protein_start="22"
                     /score="86.8"
                     /tool="antismash"
                     /translation="PAVLLLHGFPHTWELWTDIMADLSDRYRVIAPDLRGFGASGGTDS
                     GHDAGTLADDAAALLTTLGVSPAAVVGIDAGAPPAFLLALRHPGLVRRLVVMESLLGRL
                     PGAEDFLADGPPWWFGFHSAEPGLAETVLQGQEAAYIDWFLRTGTLGDGVSPTVRDAFV
                     RAYTGRDA"
     misc_feature    complement(7727..7739)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: medium, score: 23.87"
                     /tool="antismash"
     gene            7800..8246
                     /locus_tag="ME763_RS36690"
                     /old_locus_tag="ME763_36680"
     CDS             7800..8246
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006140428.1"
                     /locus_tag="ME763_RS36690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_36680"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_085563728.1"
                     /transl_table=11
                     /translation="MTTSRSDGPGRRSGARGDLLDPRCPTRRLLDRIGTKWTSMVVKVL
                     AEEEPGEVRFAELRRRIPGISQKMLSVTLQSLARDGLVGRRVEPTVPPAVHYRLTELGL
                     SLEGPLSALRVWAETHMPEIDRSNQLAEARQTCREEWEPPAEGR"
     gene            complement(8610..9995)
                     /locus_tag="ME763_RS36695"
                     /old_locus_tag="ME763_36685"
     CDS             complement(8610..9995)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013739.4"
                     /locus_tag="ME763_RS36695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_36685"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_172427429.1"
                     /sec_met_domain="DAO (E-value: 3.5e-07, bitscore: 28.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTSPTVIVVGAGIAGLTAAWRLQQAGVSVRVLERDGAPGGRMRT
                     IDHHGFRIETGASILGRNYTGMLRLIEELGLTRQFGPANTLCAFQRGNAVHRLRTHARA
                     DLLRTRLIGARTKAAVFRALPTFLAHRRCLDWDSMDRNTYLDDLSATEYAHRHLTREAI
                     DYLIEPLFGGGIVLASPDRLAAADMLFYTAKLLVPHINSPQGVGLLTRTLARRVPVQLD
                     ARVRCVRPEAEGVSVTWRDADGREHTEQAEAAVVAVPAPQVPALLPGLPDADGAYLASV
                     PYSRALIISLATERPPAERAFALFLSQREHPSLVGVELHHNKITGRVDDGRGLMTLHPR
                     QDFTDRWWDATDDTVTEQAVAAAERVFPGIRSTVLTSHVSRQDPALVVRPPGGYAELRA
                     FNGRRRSRDPRIQLAGDYFGPSSTYGALRSGEQATARLLRHLGLHTRASHRPRPDTRSP
                     HST"
     gene            complement(10001..10987)
                     /locus_tag="ME763_RS36700"
                     /old_locus_tag="ME763_36695"
     CDS             complement(10001..10987)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018491254.1"
                     /locus_tag="ME763_RS36700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_36695"
                     /product="terpene synthase family protein"
                     /protein_id="WP_085563729.1"
                     /sec_met_domain="T1TS (E-value: 4.9e-36, bitscore: 123.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGPAGNDTRALTAFARHHLLRLSPPAGDHPMARELETDVRTWAE
                     HAGLTAGGGRAGLERRRIGRLVGRCMPDVPFAVARLAARQLAWVFQFDDTVAEDTRRLA
                     AHRRWDPPGVLLTGRLPTGARSCAHLTALKSLRAGITAAGGTALLPRLAEGLRRYMESC
                     AREAPWRATGTPPDLETYLAERVHTSGGHPMYLHLLAPGMPSAAEPLPAALTGLAELAF
                     LIGALANDLLGHAAEHERGDPVNAVSVLAHSYALPLPEAYRATVVLHAAHQHRFEAERA
                     RLVDDVTLTKAQHRFVQAVTGWVRGSATAVEPYWHHLLANHPSDRTG"
     gene            complement(10984..11670)
                     /gene="uppS"
                     /locus_tag="ME763_RS36705"
                     /old_locus_tag="ME763_36700"
     CDS             complement(10984..11670)
                     /EC_number="2.5.1.-"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="uppS"
                     /inference="COORDINATES: protein motif:HMM:TIGR00055.1"
                     /locus_tag="ME763_RS36705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_36700"
                     /product="polyprenyl diphosphate synthase"
                     /protein_id="WP_107437002.1"
                     /transl_table=11
                     /translation="MSGPVPRHLAIVPDGNRRWARARGVPVRVGYARGAERTVQVLRWC
                     EEAGVETVSVWALSLENMAKRPELPVMLDAIGTLMERVRAAGPWDVRIVGSPERLAAIG
                     LPSLSGSFARSPEPADTARRFTVNLAVAYDGREEVVAAARAVLAESGPGRLDSAAIGAR
                     LARWGLPDCDLILRASGEQRLSGFLLWQSAPAELYFSPELWPDFDRGSFDAMLASFARR
                     QRRFGA"
     gene            complement(11667..13109)
                     /locus_tag="ME763_RS36710"
                     /old_locus_tag="ME763_36705"
     CDS             complement(11667..13109)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012647.4"
                     /locus_tag="ME763_RS36710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_36705"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_143657328.1"
                     /sec_met_domain="T2TS (E-value: 4.2e-47, bitscore: 159.6,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLETALAGALLDRVGGHRAESAAMRGFLSRGPRAGTLTTVERALA
                     RTVLEGGTVAVSDTLVEEVAAAAPHFTAGRKRALVHALAAAVDERFLPRWDGAAFDRSG
                     LHAWAVVQMTASKVILAHATGNTHAVDDEDVRILLDTRRGTGVWEGNVLLHLSVLHALS
                     RLPGTNRVVADGVRAALEHQRADGGLPFVTDTDTWATATAGIALASAGAPRDLLHRLAA
                     HLVNRQLPAGGWSYTDASCQADVDDTSVAVQFLHILDASRYEESITRGIRSMNSVAGPD
                     GGFPTYRRGAPSEACMTAAVVDALALRPAGHEVRIREGLGYLTRLQCADGFFPPDWSSS
                     TLHTVFRVLLAASRAPGRRTPGVERMARRALGAVLSRQNPDGGWGMREGDESDVLSTAY
                     GLIAVCGQDDPGPARGAVSFLMAAEHDGRVRGAVSDSVGPRPFVFTVPVLADVFTVLAL
                     GHLAGRTAPARLGPGRSLAVTR"
     misc_feature    13291..13305
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.89"
                     /tool="antismash"
     gene            complement(14045..14197)
                     /locus_tag="ME763_RS36715"
                     /old_locus_tag="ME763_36710"
     CDS             complement(14045..14197)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS36715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ME763_36710"
                     /product="hypothetical protein"
                     /protein_id="WP_274506831.1"
                     /transl_table=11
                     /translation="MERGWDAYQWSAWNATYGSARAAMPLLYARCATEPAGDVLLRSFN
                     LRQFW"
     gene            complement(14342..14947)
                     /locus_tag="ME763_RS36720"
                     /old_locus_tag="ME763_36715"
     CDS             complement(14342..14947)
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1117:
                     sodium/hydrogen exchanger"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013188.4"
                     /locus_tag="ME763_RS36720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_36715"
                     /product="cation:proton antiporter"
                     /protein_id="WP_274506832.1"
                     /transl_table=11
                     /translation="MPAPGVLERARRLTEEHMLLVTVLLLFLAAWYTDRLGLYAVFGAF
                     SLGMAFPRDPVVTRAVAAIAPVSRIAFLPLFFTYSGLNTDFTLLSGSGLILFTVACVAV
                     AIIGKFGACWAAARMLGEPPEIALRVGALMNARGLMQLIAINVGLSAGIASPALFGVLV
                     IVALVTTVMTAPVLTFLDRRQAARHPDENPAAEMRPAR"
     gene            complement(15074..16720)
                     /locus_tag="ME763_RS36725"
                     /old_locus_tag="ME763_36720"
     CDS             complement(15074..16720)
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018533909.1"
                     /locus_tag="ME763_RS36725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_36720"
                     /product="amidohydrolase"
                     /protein_id="WP_085563732.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.6e-09, bitscore:
                     36.1, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDTTAADLVFTGGPVHTGSPARSRATTVAVRGERVVAVGHDEVR
                     ELIGPRTEVVDLAGRLLVPGFQDAHAHPVGGGLEMGQCDLSGAATRAEYRERIAAYART
                     HADAEWITGGGWAMEVFPGGLPTAAELDDLVSDRPVYLVNRDHHGAWVNSRALERAGLD
                     ARTPDPSDGRIERLPDGTPTGMLQEGAANLVGRLVPQVTREERVAGLLRAQQLLHSLGI
                     TAWQDALLGEHANLTDPTDAYLACAEDGSLTARVVGALWWDRARDTEQIEELLARRAAG
                     TRGRLRSTTVKIMQDGVAENGTAALLGPYLDGCGCVSDNSGISFVPPEDLKTYVTELDA
                     HGFQVHFHALGDRAVREALDAVEAARRANGRTGTRPHLAHLQVVHPDDIGRFRELGATA
                     NLQPLWAAHEPQMDELTIPFLGAERASWQYPFGALLRSGATLAAGSDWPVSSPDPLQGI
                     HVAVNRVAPDAPAGTPVFLPGERIGLHDALTAYTAGSAYVNHLDHETGTVAEGYLADLV
                     VLDRDPFAGPPEEIGATRVEQTFVGGRRVFG"
     misc_feature    16732..16752
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.96"
                     /tool="antismash"
     gene            complement(16795..18282)
                     /locus_tag="ME763_RS36730"
                     /old_locus_tag="ME763_36725"
     CDS             complement(16795..18282)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018533908.1"
                     /locus_tag="ME763_RS36730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_36725"
                     /product="APC family permease"
                     /protein_id="WP_085563733.1"
                     /transl_table=11
                     /translation="MRSEPPVLRRSLGVVDGIAIAASSTAATTSIGIGMGSLAASVGLQ
                     APAILLVAFVPILGIATAYARLNRHERNMGSGYVWVGRSLGPWLGFLTGWVTLVGTLIF
                     MAYTSAVTGSVFLQFANKAQLHSVGGLRLDPNSTALSTLAGLVVLAAVTVTAVTGVRKA
                     TRFQAWLLVFEYAVLLGYCGWAMATGAHAFSWSWLNPFAVHDGTGFAQGLVLAVFFFWG
                     WDAAFSVTEETHDVRDAGRGGFIALFTMLALFLYGSVAFQREMSLPELLERGPQALTYL
                     GVKLADEPWASLPLLALLFSAVASLQSSVIPTARGLLAMGRDRTMGQVWTRVSPRYGSP
                     AVGTVLVTSISAAVALLALAIPKLNEMILAAVNSIGLVVALYYGLTALACAVRFRGMLR
                     TAPGEALRAVVAPGVSGLALLGIGCYLGRDYATMSDHFELRPDNGWFMLSVPAAIVLSG
                     LVVAAVAKYHRRSPYFVAGHSTDVGTDTVPPAATEAS"
     gene            18419..19123
                     /locus_tag="ME763_RS36735"
                     /old_locus_tag="ME763_36730"
     CDS             18419..19123
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998654.1"
                     /locus_tag="ME763_RS36735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_36730"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_274506833.1"
                     /transl_table=11
                     /translation="MRDGRIPAERRRRRPTRSGVLLSEDVIVDCALRLVGQHGPDALSV
                     RRLGAALGCDPSALYRYFHNTDDLLLAVADRIIGDAMAGFEPDRMPWRDALREMALRIH
                     RGYREQPRVAALAAYRVTRRPHEVRAVDAGIGLLRRAGFGDADAVRHYSAFVDTVLGHA
                     ALDAAHLALPPERREADDRAWTGAYAELPDADHPHLAAVRAELPLMAGSSFETALELLL
                     SALGAAAPGGTP"
     gene            complement(19133..20110)
                     /locus_tag="ME763_RS36740"
                     /old_locus_tag="ME763_36735"
                     /pseudo=""
     CDS             complement(19133..20110)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010070427.1"
                     /locus_tag="ME763_RS36740"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_36735"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAVLSRFRTDLYDCLTAHADALFELTHAVLCTDGPVRSLVDLALA
                     PEHRRGHGALYAGLNRGGLDV"
     gene            complement(20182..20898)
                     /locus_tag="ME763_RS36750"
                     /old_locus_tag="ME763_36745"
     CDS             complement(20182..20898)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS36750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ME763_36745"
                     /product="hypothetical protein"
                     /protein_id="WP_143657329.1"
                     /transl_table=11
                     /translation="MALEIPDTHSLTEVVVPSGYRGELRADVQHNPDEPPYALRRPLRA
                     SMGYVYSLREPHVRAHVIEFYESTNAPTELLAILRDLLPCLPADVPASKPQPPQALSSP
                     VQLPRRDGLYMSARGSSLGFLRFTDPANVTYVSADGEPQQIAHWLRPGSERPGIYQGSY
                     RISGRALWFTVKSPDGTAERFPSSASEDGSALSFEVENPNATRSSEVFKFAPVEFPCQG
                     ICQSMMAVRQRYGSCV"
     misc_feature    complement(21543..21552)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
ORIGIN
        1 tgctgtcgaa ccagcccagc ggcagccggg cgagtttggc cagcagccgc cggcgcaggt
       61 tccgggcgaa ccgggcgtcg acccagtgca gccagagcag cagaccggac gccagcagca
      121 gaccggcacc catcaggacg gcggcccaga tccccagagc ccacaggcgg tccgtgtccg
      181 ttcccgaggt gagccgtcgc gacagctcca ccatcagtac gaacggggcg agttggacga
      241 aggtgacgag cgtctgggcg acaccggcgg cgatcaagac ggggcgcagc ggagcgatga
      301 gccggctccc ggcctgtgcc cgccaggcgc cccgccgcgg accgggcccg gtcccggcct
      361 ggagggtgtc cgtgacggca tcggccggtt cccggacgga cacgggttcc gcggtggccg
      421 tacgccggtt ggaaccgaag gcccgcccgt ggtaccagta cgcctgggcg tgcgtctcgg
      481 tgcgggggaa gccgaactcg tcgcgcagcc gtgtgcgcag gtgcttgagc gaaccggact
      541 ccggcgtgac ccaggcgtac cagtcggacc agtcccgggc cgggatcgcg gcggcgagcg
      601 actccggccc ccggcgcggc acccagtgga cgttcatccg ggggtgctcc ccgaggggaa
      661 tgagacggtc cgtctcctga tgctcctcca ggtagagctc cacgggcact tccgtgggca
      721 gcgcgtcgag gatgccgttg atcgccggta cggaagcggc gtcaccgacc agcaggtatc
      781 cggcgggcgg atcagacggc aggtcgaagc ggctggaacc cagcgaggtc actcccaccg
      841 tcgttccggg tgctgcccgc cgcgcccagg cggacgccgg gccggccggt tcgtggagta
      901 cgaagtccac cgcgaacgct ccggttgcgg ggtcggcctc ggacaacgtg tatccgcgct
      961 gatgctcggt ctcggggtcg tccggatccg gcatccagaa ccgcacatat gccgccgggc
     1021 ccaccaccac gtcctccagc agcgtggggg aggtcatccg gacgcgcagg aagtgcgggg
     1081 cgagcagttc cgttccggtg accgtggcct cgtggtcgcg cgcaccgtag gcgcgcatga
     1141 tcaccccgct gacgccgcgt ctggccatca ctgtccctct ccggcggcga gcagcgccgc
     1201 cctgatctcg tgcaaggggc ggccgggggg cgctgcctcc acgaagccgc ggatcgcggc
     1261 tcccagccac atccggacgt attcgtcggg ggtgatcgtc ggcagggcgc ggtgtgccgc
     1321 accgaggcgg gcgtcggcca ggagtgcctg ttcgacgccc cggcgctgcg cgtcgagttc
     1381 ctcggcccgc tcccgctggg tctcctcggt cgccgtgtag ccgatgacca cagacgcgac
     1441 ggcggccgac aggacgatgc ccgcctcggt ggagtacccg cgccgcgtca gtgactccgc
     1501 cgccgtggcg agcagccgcc tgcctccttc accccgtggg aacagggtct gcacataccc
     1561 ggtcaggccg ggatggcgca gcatgaacgc ccgcaactgg agtgcggtgg agagcagatg
     1621 aggcaccgga ccgtcggacg ggtcgtcgcg gaggtcgagt tccgccagca ggctctcgcc
     1681 caccagccgt tccagccccc accgcccgtc cacatggcgg tacagcgcgg cggacgacac
     1741 ccccaggcgc gccgccacgg cgttcaagct caggttccgc agcccgagtt cccgtccgac
     1801 ccggacgatg tcggccggct cgatctgccg tggccggccg ccggttcgtg ccatccggat
     1861 actcccgccc cttaaagtta cccccactaa ctaaggttag cctaaccttt catgaggcga
     1921 tgggtaaccc cctggcgccg tcgcaggtgc aggtgccggt gcagcgacgg aacgtcacaa
     1981 gtgggggcgg aggcacggcg gacggcttct cggcaacgcg tgagaaggcg gcgccgggga
     2041 cggccacggc ccggtccgtt gcagccttct ccgtcgaaga tccgccgtcg gctcagagga
     2101 agttgttcgg ccagatcatg gtgcgccaca tgtgggccac cggagagctg tcgaagccca
     2161 ggccctcggc gggctggcgg aagtggcgcc cgaccacgtc ctcgaactcc tcgaactcga
     2221 catggacatc ggggtcgaag gtgtacaggt cgttgatggt gaccatgcgc gccgacatgt
     2281 accagcggtg ccggcgggcc tcgaggtagg cggcccgagt gtgggcgggt ggctggtact
     2341 cggcaccgaa gaagtcgctg tacgcctccg ggtatccata gcccacgctc tcgtcgggga
     2401 agtagcgcag gatctcgtgc tggcggatcg cccaggccac ttcctcgtcg acgtacggac
     2461 ccaccagttg ggcgccccag tggccgtgct ggctgcgcag caggccggcg accgagatgt
     2521 cgtgcagcag acaggccagc accactttgt cgtccgcccc ctgctcccgt gccttgcgcg
     2581 cgctctgcat catgtgccgc gtggtgaagg gatcgagagc gagccgacgg cggaagaagt
     2641 cggcgagggt gggctgttcg ggcatggcgg gaagcgtggg gttgtctccc atcatgaaca
     2701 cctgtcccga ctctctcgag gacagccacc tgtcgccgga gcggtgacca tcggtcccca
     2761 gggtcgcagc agccggcgga cagatgacgc gggcgtgctt gtgctggccg tgagacacgt
     2821 actgcctttc tgacgggtgc catccgatcg ggcaccgaga ccttgatctc atcaggaaga
     2881 tcaacagctg aagttcctga ttcacccgaa tggcggagct tgcgacggga aaccccccgc
     2941 tacggtgagc ccggcgcaca acagctcgaa gtgtcgcgcc accggctgcg cgtgcacgtg
     3001 gcagtgggcc ggccggctcc cgccgacgtg gcgggcggcg tcggtgaatg aagcgagttc
     3061 atccatttga ccgacgatcc gactggttga atgctggacg tcgtgacgcg cagaaggcga
     3121 ggaaccgcat cggccgagac gaccactccg ggggagcccc gcggcgaggc tcagggagac
     3181 ctaggcggtg tcttcaaatg atcgctgctg gtggatgatg gtgtcgtgat acgtcgccat
     3241 gaactgtccg atgccgagtg ggagttcgtc cggccgttgt tgcccgagtc gttgcgaggg
     3301 cggaagcggc tggacgaccg cagggtcctg aacgggatcg tgtggaagtt ccgtaccggg
     3361 acggcctggc gggacgtgcc cgagcgctat ggtccgtggg ccacgctgca tacccgattt
     3421 cgcaggtggg cggcggacgg gacgttcgac cggatgctgc gggccgcgca ggcgggggcg
     3481 gacgcggcgg gcgacgtcga gtggctggtc tcggtcgatt ccacgatcgt ccgcgctcat
     3541 cagcatgctg ccggggcccg aaaaggggga tcctcgaccc ggccctcggc cggtcaagag
     3601 gcggtctgac cagcaagatc cacctggcct gcgacggccg gggccgcccg ctcgccttcg
     3661 tcgtcacggg cggcaatacc aacgactgca cccggttcac cgccgtgatg gaggcgatcc
     3721 gggtgccccg cctcggaccg gggcgacccc gtatccggcc cgatcatgtc ctgggcgaca
     3781 agggctacag ctcgaaggcg atccgtgcct ggctccgccg ccacggcatc ccgcacacga
     3841 tccccgagcg ggccgaccag gttcgcaacc gggcccggcg aggcagccgc ggtggccgtc
     3901 cgccggcctt cgaccgcgag gcatacaagc accgcaacgt cgttgaacgg tgcttcaacc
     3961 gcttgaagca gtggcgaggc atcgccaccc gctacgacaa gaccgcccag tcctacgaag
     4021 cagccgtcgc cctcgcctca ctcctgatgt gggcgtgaca tttgacgaca gaacctagcg
     4081 gaaggggcgg cgggctccgg tctgtccact cgtctcctcg tgctcatgtc cgtcggagcg
     4141 ggtatgtcgg cggccaacac gtactacgtg cagccgctgc tcgacacgct cggccatgac
     4201 ttcggggtcg gcagtgggat cgccgggctg gtcacgacct tcgcccaggt cggctacgtc
     4261 ctgggactgg ccctgatcgt gccgctgggg gacctggtgg agcgccgccg cctggtgacg
     4321 atcacgacgg cggtcaccgg gctggggctg ctggggatgg ccgcggcacc gaacatcgcg
     4381 gtactgatgg cgctggcggc ggtcgtgggc ttctgtacgg tgacggccca gatcttcgtc
     4441 cccttcgcgg cccatctggc gaccccgatg aatcgcgggc gctccgtggg gatcgtcatg
     4501 agcgggctgc tgatcggcat tctgctcgcc cggaccgtgt ccggcgtcat cgccggagcc
     4561 acgagctggc gggtcgtcta cctggtcgcc gccgtgctga cgttcgcgct gtccgtggcc
     4621 tgccgcatgg agctgccgtc ctcggcgccg accacccgca ccgcttatca ccggttgctc
     4681 ggatcggtgg cccggatcta tctggacgaa cccgctctcc gccgccgcgg actctacggg
     4741 gccctcgtgt tcgcgtcgtt cagcaccttc tggaccgcga tcgccttcca gatggccgat
     4801 caataccact tcagccagac cgtgatcggg ctgttcggtc tgctcggcgt cgccggcgcc
     4861 ggctgtgcgc aggtggccgg gcgcatcgcc gacgcgggct ggggacgtgt ggccacggcg
     4921 ggattcatcc tgctcaccgc ggtcagctgg atcgccgggt gggccggtgg ctcccgcatc
     4981 ggctggctgg tcgccgggat cgtggtgctc gacctggggg tgcagggcac ccatatctcc
     5041 aaccagagcg aggtctaccg gttgcgcccg gaagcgcgca gccggctcac caccggttat
     5101 atgtgcacct acttcgtcgg cggggtcacc ggctccgcgc tggccggtgc tgtctacggc
     5161 gcctacggct ggaagggggt ctgcctgctc ggcgccgttt tccccaccct ggcactcctc
     5221 gtctggctga ccgaagcccg ctggccactg cggaccatgg cccgaggatg acgtcgaatc
     5281 cgcgcgggcg ggttacggcg caccggcatt cgggcatcgt cgcggacagc gacccggagc
     5341 ctgctgctcg gcggctccgg atcggatcaa atccgggcgt ggtccgtcct gttcgtccgc
     5401 cggccgtcgc gcgggcccct gcggtcagat ctgggccaga ccgccgtcga cgaagaactc
     5461 cccgcctgtg ctgaaggaac tctcgtcgcc ggccaggaag agggcgaggg cggcgacctc
     5521 gtccggacgc cccatccgtc cgagcgggac ctgagcggtg aaaccgtccg tcagccgtcg
     5581 gcgggccgca gggttgtcac ccgcgagacc gaggatgccg ggggtctcga tcgggccggg
     5641 gctcacggcg ttgacgcgga taccgcgctc ggccagttcc gcggcccagg agcgggcgag
     5701 gctgcggatg gccgccttgg tcgcgctgta gacgctcatg gcgggcacgc ccttggaggc
     5761 gttggtggag gacagcagga tgaccgaccc tccccggtcc agcaggggca gcgccttctg
     5821 ggcggtgaag acgatgccct tgacgttgat cgcgaaggta cggtcgtagt cctcctcggt
     5881 gatgtttccc agccgtgcca gctcaccgcc gcccgcgttg gcgacgagga cgtccagacg
     5941 gcccgagcgg tcttggatct cggcgaagag acggtcgatg tcgtcgaggt cggacacatc
     6001 accgcggacc gggacggccc tgtcgccgag ctgctcggcc gcggccttga gttcgctctc
     6061 gcggcggccg gtgatgtaga cggtcgcgcc ctccttcacg aagcgctcgg ctatgccgag
     6121 tccgataccg gtcgaggcgc cggtgacgag ggcgatcttg ttgtcgagct gtcccatggt
     6181 ttcgctcctt gtaactgcga cggtgtaact gtgacggtta cgtctatggg cgaggtcgga
     6241 cgtcccgtga gccggatggt tccggcccgc ggtcagcgag cggcgagaac gccacgcagg
     6301 acatcggcca gggtcgacgc ggcgagctcc tgccgcacag cggcctctgc ccggtcgtag
     6361 atctttccga tcgcgggctg gattccccgg ccgaccggac actcctgatt gggcggggtg
     6421 cggtgcatgg cgaacagggg tccggactcg acggcgtcgt acacctccag gaggccgatc
     6481 cgagccgggt cacgagccag gacccagccc gcgcccgcgc cgcgccggga ggagacgaga
     6541 ccggccctgc gcaggtcacc gagcaggcgg cggaccacga ccgggttggt gttcacgctc
     6601 tcggagatct gctcggacgt ggccaccgtg ccgccctggc gccggtacag ctccatccac
     6661 acgagcacat gggtcgcgac cgtcagccgg ctgttggcgc tcacccgtac cacctcccag
     6721 atgtaaccgt aacagttaca tcgccgtcgc gtgccgtccg agccgtttcc ctccgcacgg
     6781 gaccgccgac ggatgcggca ggatccggca ccggagtggg cggacagccg ggctctcctg
     6841 gcgatgtcac gctgcgaccc cgtcctcgcc cgccaggaac ggacgcagca gcgtgagcag
     6901 ggcgtgcggc cggtgcagcg gaatgatgtg gccgcagtcc tcgatgacgt gcccgacgag
     6961 gtcgtccgcg accgggcgga gctggcgttc cagcgcggag ccgacgggcc gggcacccag
     7021 cgccatggtc ggcacggtca ggcgggcgtc ggtggtcgcc tgctcgatct gcagcgcgct
     7081 ctcgggcagg gcccggtagt acgagaacgc gcggctcagc gcgtccctgc ccgtgtacgc
     7141 gcggacgaaa gcatcccgga cggtggggga cactccgtcg ccgagcgtac cggtgcgcag
     7201 gaaccagtcg atataggcgg cctcctggcc ttgcagcacg gtctcggcga gtccgggctc
     7261 ggcggagtgg aagccgaacc accacggcgg gccgtcggcg aggaagtcct cggcgccggg
     7321 cagccgtccc agcagggact ccatgacgac caggcgccgc acgagaccgg gatgacgcag
     7381 ggcgaggagg aaggccggcg gggcgcccgc gtcgatcccg acgaccgcgg ccggggacac
     7441 gccgagcgtg gtgagcagcg cggcggcgtc gtcggccagg gtgcctgcgt catgcccgga
     7501 gtcggtcccg ccgctcgcgc cgaacccgcg caggtccggc gcgatgacgc ggtagcggtc
     7561 ggacaggtcg gccatgatgt ccgtccacag ctcccaggtg tgcggaaagc cgtgcagcag
     7621 caggacggcc gggcctgatc cggcgagagc gacgttcagt tcgacgccgt tgacggggat
     7681 gcgccgcagc tcgggcacga gaggactcca ggggtggtga ggaatggtga cagggtcacg
     7741 ctagggaact accctgggcc gtccaagacg gcactttcct ctcaggtggt gagccccggg
     7801 tgaccacatc gaggtccgac ggacctggtc ggcggtccgg tgcgcgcggt gatctgctgg
     7861 atccgcgctg cccgacgcgc cggttgctcg accgcatcgg caccaagtgg acgtcgatgg
     7921 tggtcaaggt gctggccgaa gaggaacccg gcgaggtccg cttcgcggaa ctgaggcgcc
     7981 gtattccggg catctcacag aagatgctgt cggtcacgct gcagagcctg gcgcgtgacg
     8041 gcctggtcgg acgccgggtg gaacccaccg tgccaccggc cgtccactat cggctcaccg
     8101 agctgggcct gtccctcgaa gggccgctct ccgcactgcg ggtgtgggcc gagacgcaca
     8161 tgccggagat cgaccggagc aaccagctcg ccgaagcccg gcagacatgc cgggaggagt
     8221 gggagccgcc ggccgagggt cgatgacggt tcggagtacg gccgcctcgt agtgggctgc
     8281 cggcccggtc gtgccgtgcg gcgacggcgc ggcgcctctc gcggcagtcg atcccgcacc
     8341 ccgcgccgcg atccttgtgc accgccgccg acgggcgcgc gaccctccgg ggagtcggtc
     8401 tcgccggagc agcggcccgc ggaagctccg cacgcccagg acctgccgga ggcgcatggc
     8461 tgcccggaag agcggcgacc agacgtaccg ctgcggccgt acggcgcagg tgggatcagt
     8521 ctccgggagg gtacgacccg ggtactcggg gtcggtgtcc ggagccgcgg ccgtggcaga
     8581 acgcgcctcc tcggacggga gagccgtcct cacgtcgaat gcggtgaccg tgtgtccggc
     8641 cgaggtcggt gggaggcccg ggtatggagc cccaggtggc gcaggagccg ggccgtggcc
     8701 tgttcgccgg agcggagggc gccgtaggtg ctggaagggc cgaaatagtc acccgcgagc
     8761 tggatacggg ggtcccgcga gcggcgtcgg ccgttgaagg cgcgcagttc ggcgtagccg
     8821 ccggggggcc ggacgacgag ggcggggtcc tggcggctga cgtggctggt caggacggtg
     8881 ctccggatgc cggggaagac acgttcggcg gcggcgacgg cctgctcggt gacggtgtcg
     8941 tcggttgcgt cccaccagcg gtccgtgaag tcctggcggg gatggagggt catgagcccg
     9001 cgcccgtcgt cgacccgccc ggtgatcttg ttgtggtgga gttcgacacc gacaagcgag
     9061 gggtgctccc gctgggagag gaacagcgcg aacgcccttt ccgcgggcgg gcgttccgtc
     9121 gccagcgaga tgatcagggc tcgggagtag gggacggagg cgaggtaggc gccgtccgcg
     9181 tcgggaaggc cgggcagcag agccggaacc tggggagcgg gtaccgccac gacggcggct
     9241 tccgcctgtt ccgtgtgctc gcgaccgtcg gcgtcccgcc atgtgacgga gacgccctcg
     9301 gcctccgggc ggacacagcg gacgcgggcg tcgagctgca cgggaacacg gcgggccagc
     9361 gtgcgggtga ggagcccgac cccctgggga ctgttgatgt gcgggacgag gagtttcgcg
     9421 gtgtagaaca gcatgtcggc ggcggccagc cggtccggtg aggcgaggac gatgcctccg
     9481 ccgaagagcg gctcgatcag atagtcgatc gcctcccgag tgagatggcg gtgcgcgtac
     9541 tcggtggcgc tgaggtcgtc caggtaggtg ttgcggtcca tgctgtccca gtcgagacac
     9601 cggcggtggg cgaggaaggt cggcagtgcg cggaacaccg ccgccttggt ccgcgcgccg
     9661 atcagacggg tgcgcagcag gtcggcccgc gcgtgggtgc gcagccggtg gacggcgttg
     9721 ccgcgctgga acgcgcagag ggtgttggcg ggcccgaact ggcgggtgag accgagttct
     9781 tcgatgaggc ggagcatgcc ggtgtagttg cggccgagga tgctggcacc ggtctcgatc
     9841 cggaacccgt ggtggtcgat ggtgcgcata cggccgccgg gcgcgccgtc gcgttcgagg
     9901 acgcgtacgg acacgccggc ctgttgcagg cgccaggccg cggtcagccc ggcgatgccg
     9961 gcccccacga cgatgacggt gggcgaagtg ggcacagcgg tcagcctgtt ctgtcgctcg
    10021 ggtgattggc gagaaggtga tgccagtacg gctccacggc cgtcgcgctg ccccgtaccc
    10081 agcccgtgac ggcctggacg aagcggtgct gggccttggt gagtgtcacg tcgtccacca
    10141 gacgggcccg ttcggcctcg aaacggtgct ggtgtgccgc gtggagcacg acggtggccc
    10201 ggtacgcctc gggcaggggc agcgcgtagg agtgggcgag gacggagacc gcgttcacgg
    10261 ggtctccgcg ttcgtgctcg gcggcgtgac cgagaaggtc gttggcgagc gcgccgatca
    10321 ggaaggcgag ttcggcgagg ccggtgaggg cggcgggcaa cggctccgcg gccgatggca
    10381 taccgggggc cagcaggtgc aggtacatcg gatggccgcc cgaggtgtga acccgctcgg
    10441 ccagataggt ctccaggtcc gggggagtac ccgtagcacg ccacggggcc tcacgcgcac
    10501 agctctccat gtaccggcgc agtccttccg cgagccgcgg gagcagcgcg gtgccgcccg
    10561 cggccgtgat gcccgcgcgc aaggacttca gcgcggtcag gtgcgcacac gaccgtgccc
    10621 cggtcggcag ccgcccggtc agcagcaccc cgggcgggtc ccagcggcgg tgcgccgcca
    10681 gccgtcgcgt gtcctcggcg accgtgtcgt cgaattggaa cacccaggcc agctggcgtg
    10741 ccgccaaccg ggccaccgcg aagggcacgt ccggcatgca gcggccgacg agacggccga
    10801 tcctccggcg ctccagtccc gcccgcccgc cgccggccgt cagacccgcg tgttcggccc
    10861 aggtccgtac gtccgtctcc agctcccggg ccatggggtg gtccccggcc ggcggagaca
    10921 gcctgagcag atggtgccgg gcgaacgcgg tcagcgcccg cgtgtcgttc cccgccggac
    10981 cggtcatgcc ccgaacctgc gctgtcggcg ggcgaacgag gcgagcatgg cgtcgaagga
    11041 cccgcggtcg aagtccggcc acagctccgg gctgaagtac agttccgcgg gcgcgctctg
    11101 ccacagcagg aagcccgaga ggcgctgttc gcccgaggca cgcaggatca ggtcgcagtc
    11161 gggcagcccc caccgggcga ggcgggcacc gatcgccgcg ctgtcgaggc gcccgggccc
    11221 ggactcggcc agtacggcgc gtgcggcggc cacgacctcc tcccggccgt cgtacgccac
    11281 ggccaggttg accgtgaacc gccgtgcggt gtccgccggt tcggggctcc gggcgaagga
    11341 gccggagagc gagggcagcc cgatggcggc cagccgctcc ggtgacccga cgatccggac
    11401 gtcccatggg cccgcggccc ggacccgctc catgagcgtg ccgatcgcgt ccagcatgac
    11461 gggcagttcc ggacgcttcg ccatgttctc cagcgacagg gcccagacgc tgaccgtttc
    11521 cacccccgcc tcctcgcacc accgcagcac ctggacagtc cgttccgctc cacgcgcgta
    11581 ccccacccgg accggaacgc cgcgcgcacg cgcccagcgc cggttgccgt ccggcacgat
    11641 ggccaggtgc cggggaaccg gcccgctcaa cgggtcaccg ccagcgaccg gccgggcccg
    11701 agccgcgccg gtgccgtccg gcccgcaaga tgccccagtg ccaggacggt gaagacgtcg
    11761 gccaggacgg gcacggtgaa gacgaacggc cggggtccga ccgaatcgga gaccgctccc
    11821 cggacccggc cgtcgtgctc ggccgccatc aggaaggaga cggcgccgcg cgcgggccct
    11881 ggatcgtcct gcccgcacac ggcgatcaga ccgtaggccg tggacaggac atcgctctcg
    11941 tcgccctccc gcatccccca gcccccgtcg ggattctggc gcgacaggac ggcgcccagg
    12001 gcgcgtcgcg ccatccgctc gacccccggc gtcctccggc cgggagcgcg ggaggcggcc
    12061 agcaggaccc ggaagaccgt gtgcagggtg ctgctgctcc agtcgggcgg gaagaacccg
    12121 tcggcacact ggagtcgcgt caggtagccg agcccctcac ggatccggac ctcgtgtccg
    12181 gcgggccgga gggccagcgc gtcgacgacg gctgcggtca tgcaggcctc cgaaggcgcc
    12241 ccacggcggt acgtggggaa gccgccgtcc ggtcccgcga ccgagttcat cgaccggatc
    12301 ccccgcgtga tcgactcttc gtaccgagag gcgtccagga tgtggaggaa ctgcaccgcg
    12361 acggaggtgt cgtccacgtc cgcctgacag gacgcgtcgg tgtatgacca cccccctgcg
    12421 ggaagctgac ggttcaccag gtgggcggcc agccggtgca gcaggtcgcg cggagcaccc
    12481 gcgctcgcca gggcgatccc cgccgtcgcg gtcgcccagg tgtcggtgtc ggtcacgaac
    12541 ggaagcccgc cgtcggcacg ttggtgttcc agcgccgcac ggacgccatc ggccaccacc
    12601 cggttcgtac cgggaagacg ggacagggcg tgcagcacgg agaggtgcag cagcacattg
    12661 ccctcccaca caccggtgcc acgccgggtg tcgagcagga tccgtacgtc ctcgtcgtcg
    12721 accgcgtgcg tgttcccggt cgcgtgcgcc aggatcacct tgctcgcggt catctggacg
    12781 acggcccagg cgtgcaggcc cgaacggtcg aacgccgcgc cgtcccatct gggcaaaaac
    12841 ctttcgtcca cggctgctgc gagcgcgtgc acgagcgccc gtttgcgtcc ggccgtgaag
    12901 tgcggggcgg ccgccgccac ttcctcgacc agcgtgtccg acacggcgac cgtcccgccc
    12961 tccagcacgg tccgagccag cgcccgctcc accgtggtga gcgtgccggc tcgtggtccc
    13021 ctcgacagga agccccgcat cgccgccgac tcggcccggt ggccgccgac gcggtccaac
    13081 aaggccccgg ccaaggccgt ttcgagcaca cggctctcac acgggtcccg cagggctccg
    13141 tccggcccca cccgcgcggc cagggctgcg accatacggc cacgcgccga cgcgcttccc
    13201 agcggcatct tcgaggcagg ccaggtactc gctcccgacc ggtccctcat ccgcatcgac
    13261 tggtccttcc gttgatcatt ccgacggcgg ttctccagta gagatcaaga acaaggacca
    13321 cgaaccgaag tcgatccggt tcacccgaaa gtggtacccg cggggggaga acacgggcgg
    13381 gagggtgcat gatctgaggc gtcgtccgga gaacggccgc cgcggggagg cggggccgag
    13441 cggctgggac ggaggcatcg gcaccgtgcg ccgccgtgtc gcggccgccg gtgacctact
    13501 ccgctgatcc ggcggacacg aggcagagcg aagccgtggc gcgccgggca gttgtcggcc
    13561 cgcttcgtcg gcacggggat ccgggccacg ccaccgggcc ggcccggcag caccggggac
    13621 tccgcgaggt cggctccgga tgcggctcac cgacttcggc gcaggggagc gatcaacctg
    13681 ctcgaatgcc ctcggccggg actacgagaa gggaacccac cgcctcaccg ttccatgttt
    13741 ccgactccgc ccccggaccg gcatggccaa ggccgtccac ctgtgcttcg cgtacgacgg
    13801 cgacggcgcc cgagcgaggg ctggacgccg aggacgggca ggtcggccca ggcccgtctg
    13861 atggaccggt ccggcagcgg ccggggactc gctgcgtgcg aaccgtgagc ctgccgaggt
    13921 gccgcagccc cgccgaagcc ctgccgaaac cggaggtaga gccggccggg acgctggacc
    13981 tcatggccgt acccgatggg gtcgagcacg cctcgtcctc cccgcgacac cggcacccca
    14041 cctctcacca gaactgccgc agattgaagc tccgcagcaa gacgtcgccc gcgggctcgg
    14101 tggcgcatct ggcgtacagg agcggcatcg ccgctcgggc ggagccgtac gtggcgttcc
    14161 aggccgacca ctggtacgcg tcccaccctc gttccatgcc gatccccacg ccggccttct
    14221 cccgcgtggt cagggagccg ggcggtggtg gaaggcgacg tcgtggctga tcacccacat
    14281 cccctgaagt gacgacggaa tctcggatcg tcaggtggca ccccgcccgg tgcccccccc
    14341 gctaccgagc agggcgcatc tcggccgcgg ggttctcgtc cgggtgccga gccgcctgac
    14401 gccggtccag gaacgtcagt acgggagcgg tcatcaccgt ggtgaccagg gcgacgatga
    14461 ccaggacgcc gaagagggcc ggcgaggcga tgcccgcgct gaggccgacg ttgatggcga
    14521 tgagctgcat cagcccgcgc gcgttcatca gcgcgcccac ccgcagggcg atctccggcg
    14581 gctcgcccag catccgcgcc gccgcccagc acgcaccgaa tttgccgatg atcgccaccg
    14641 ccacgcaggc gacggtgaac aggatcagac cgctgccgga cagcagcgtg aagtccgtgt
    14701 tgagccccga gtaggtgaag aacaggggca ggaacgcgat gcggctgacc ggtgcgatgg
    14761 ccgccacggc gcgggtcacc accgggtcgc gaggaaaggc catgccgaga ctgaaggcgc
    14821 cgaacacggc gtacaggccg aggcggtcgg tgtaccaggc ggcgaggaac agcaggagca
    14881 cggtgaccag cagcatgtgc tcctcggtca gccgtcgcgc ccgctccagg acacccggcg
    14941 cgggcacgtc ggcccgcgtg acggaatgcc gtaccactac cgcgtgaccg tgcgttcgca
    15001 ggcgaagccc tcgactgccg cgcatcaacc gcagccgaag actgcggctt ccgtcgcacc
    15061 acggacgcct gactcagccg aacacccggc gcccgcccac gaaggtctgc tccacccgcg
    15121 tcgcaccgat ttcctcgggc ggcccggcga acggatcacg gtcgagcacc accagatccg
    15181 ccaggtaccc ctcggcgacc gtgcccgtct cgtggtcgag gtggttcacg taggcgctac
    15241 cggccgtgta cgcggtcagc gcgtcgtgca gcccgatgcg ctccccgggc aggaagaccg
    15301 gcgtacccgc gggcgcatcc ggtgccaccc gattcaccgc cacgtggatg ccctggagcg
    15361 gatcggggct gctcaccggc cagtcgctgc ccgccgcgag cgtcgccccc gaccgcaaaa
    15421 gcgccccgaa cgggtactgc cacgacgccc gctccgcacc caggaacgga atggtcagct
    15481 catccatctg cggctcgtgc gccgcccaca gcggctggag gttggccgtc gcgcccagct
    15541 cacggaaccg gccgatgtcg tccgggtgca ccacttggag atgggccagg tgcggccggg
    15601 tccccgtacg gccgttggcc cgccgggccg cctccaccgc gtccagcgcc tcccgcaccg
    15661 cgcggtcgcc cagcgcgtgg aagtgcacct ggaaaccgtg ggcgtccagt tcggtgacgt
    15721 acgtcttcag gtcctccggc ggcacgaagc tgatcccgct gttgtcggac acgcacccgc
    15781 agccgtccag gtacgggccg agcagcgccg ccgtgccgtt ctcggcgacc ccgtcctgca
    15841 tgatcttcac agtcgtcgag cggagccggc cccgggtgcc cgccgcgcgc cgggccagca
    15901 actcctcgat ctgctcggtg tcacgcgcgc ggtcccacca cagcgcgccg acgacccgcg
    15961 cggtgaggga tccgtcctcg gcgcaggcca ggtacgcgtc ggtggggtcg gtgaggttgg
    16021 cgtgctcgcc gaggagagcg tcctgccagg cggtgatgcc gagcgagtgc agcagctgct
    16081 gggcgcgcag cagcccggcc acccgctcct cgcgggtgac ctgggggacc agacggccca
    16141 ccaggttggc ggctccctcc tggagcatgc ccgtcggcgt gccgtccggg agccgctcga
    16201 tccgcccgtc ggacgggtcg ggggtacggg cgtcgagtcc cgcccgctcc agagcgcggg
    16261 agttgaccca ggcgccgtgg tggtcgcggt tgaccagata gaccggccgg tcggacacga
    16321 ggtcgtccag ttcggccgcc gtcggcaggc cgccggggaa cacctccatc gcccagccgc
    16381 caccggtgat ccactcggcg tcggcgtgcg tccgggcgta cgcggcgatc cgctcccggt
    16441 actcggcccg ggtcgccgcc ccgctcaggt cgcactggcc catctccagg ccgccgccga
    16501 cggggtgcgc gtgcgcgtcc tggaagcccg gcaccagcag ccggccggcc aggtccacga
    16561 cctcggtgcg cggaccgatc agctcgcgca cctcgtcgtg cccgacggcg acgacccgct
    16621 cgccgcgcac ggccacggtg gtcgcccggg accgggccgg cgaaccggtg tggaccggac
    16681 cgccggtgaa gaccaggtca gcggcagtgg tgtcggacat gaggacaact cctagcgtcg
    16741 gtaaggctct tacggatgct gccggtgtcc cggccgctac gggttctacg ggcgtcagga
    16801 agcttcggtc gcggccggcg ggacggtgtc ggtgccgaca tcggtgctgt gtccggcgac
    16861 gaagtacggc gagcggcggt ggtacttggc gacggccgcc acgacaagcc ccgacagcac
    16921 gatcgcggcg ggcaccgaca gcatgaacca gccgttgtcc gggcggagtt cgaagtggtc
    16981 gctcatcgtc gcgtagtccc ggccgaggta gcagccgatg cccagcagcg cgagcccgct
    17041 cacaccgggc gcgacgaccg cccgcagtgc ctcgccgggc gccgtgcgca gcatgcctcg
    17101 gaagcgcacc gcgcaggcga gcgcggtcag gccgtagtac agggcgacca cgaggccgat
    17161 cgagttcacg gccgcgagga tcatctcgtt cagcttgggg atggcgagcg ccagcagcgc
    17221 cacggccgca gagatcgacg tgacgaggac ggtgccgacc gccggggagc cgtagcgcgg
    17281 gctgacccgc gtccatacct ggcccatcgt gcggtcccgg cccatcgcca gcagcccgcg
    17341 cgccgtcggg atcacgctgg actgcagcga cgccaccgcc gagaacagca gcgccagcag
    17401 cggcaggctc gcccacggct cgtccgcgag cttcacgccg aggtaggtga gtgcctgcgg
    17461 tccccgctcc agaagctcgg gcagcgacat ctcccgctgg aaggccacgg acccgtacag
    17521 gaacagcgcc agcatggtga acagcgcgat gaatccgccg cggcccgcgt cccgtacgtc
    17581 gtgggtctcc tcggtgacgc tgaacgccgc gtcccagccc cagaagaaga acaccgcgag
    17641 gaccaggccc tgggcgaagc cggtgccgtc gtgcacggcg aacgggttca gccatgacca
    17701 ggagaaagcg tgcgcgccgg tggccatcgc ccagccgcaa tagccgagca gcaccgcgta
    17761 ctcgaagacc agcagccacg cctggaaccg ggtcgccttg cgcaccccgg tgacggcggt
    17821 gaccgtgacg gccgccagca ccaccaggcc ggccagggtg gacagcgccg tcgagttcgg
    17881 gtcgaggcgc agcccgccga ccgagtgcag ctgggccttg ttcgcgaact ggaggaacac
    17941 cgagccggtc accgcgctcg tgtacgccat gaagatcagg gtgccgacca gcgtgaccca
    18001 gccggtgagg aagccgagcc agggaccgag cgagcgaccg acccagacgt agccgctgcc
    18061 catgttccgc tcgtgccggt tgagccgggc gtacgccgtc gcgataccga ggatcgggac
    18121 gaacgccacc agcaggatcg ccggcgcctg aaggcccacg gacgcggcga gcgagcccat
    18181 accgatgccg atactcgtgg tggcggccgt gctggaggcc gcgatggcga tgccgtcgac
    18241 gacacccagg gaacgccgca ggacgggagg ttcacttctc atggacagac tcctggagcc
    18301 ggagaacggg aggtgcggga ggaggctgcg atcaaaccgg ccttgtcaac attgcgtcaa
    18361 tggtgttgac ataaggcgtt cacggaacgg ttcagagccg agggaagggg cgcgtacggt
    18421 gagggatggg cggattccgg cggagcggcg acggcgcaga ccgaccaggt cgggggtgct
    18481 gctgtccgag gacgtgatcg tcgactgcgc gctgcggctc gtcgggcagc acggcccgga
    18541 cgcgctgagc gtgcggcggc tgggcgccgc gctcggctgc gatccgagtg cgctgtaccg
    18601 gtacttccac aacaccgacg acctgctgct ggcagtcgcc gaccggatca tcggcgacgc
    18661 gatggccggg ttcgagcccg accgcatgcc gtggcgggac gcgctgcgcg agatggcgct
    18721 gcggatccac cgcggctacc gggagcagcc gcgggtggcc gcgctcgccg cgtaccgggt
    18781 gacgcggcga cctcacgagg tcagagccgt ggacgcgggg atcgggctgc tgcgccgggc
    18841 cgggttcggc gacgccgacg ccgtgcgcca ctattcggcg ttcgtggaca ccgtgctggg
    18901 ccacgcggcc ctcgacgccg cccacctggc gctcccgccg gagcgccgcg aggccgacga
    18961 ccgggcctgg accggcgcct acgccgaact gcccgacgcc gaccacccgc acctggccgc
    19021 ggtacgcgcg gagttgcccc ttatggcggg cagctcgttc gagacggcac tggaactgct
    19081 cctgagcgcg ctgggagcgg cggcgccggg gggcacgccc tgagcttgtt gcttaactcg
    19141 ttcgtcgtgg tttggtgccg accttgtggt gggccggtcg ctggtacggc tcgctaccgg
    19201 cgaggactcg tcccacgtcg tggcggggtg caggtcggcg gttcttcgat ccgggtgggc
    19261 gtccggggcc ggggcgggtg ggttttggtg caccggccgg cgaaccggtc gtcgtgcgga
    19321 ggttccgaga cccgcgccgg acccgggccg gggtgagctt gtggggtggc gctggcttct
    19381 cccacggccg ccgcaggtcg gtggcgaggg ggcgggcgag gcagagctgg gtgtggccgg
    19441 cgatgatcag ccacgtccag cggtcggcgg ctgcggagtc gcgcggtcgg gccggggcca
    19501 gccgaggtct gtttgagcct gcggaacgtg tgctcgatgt cgaagcgccg caggaacgcc
    19561 tgccggcagc ggtcgacgtc ggcttcggtt gcgccggtgc gcgaccacca cagccagacc
    19621 ggcttgttca ccccgccgga tggcaggtgc tcgaccgaca ggcggatgac ggtgccctcg
    19681 atgaccggca gcggcccggc gtggtcgagc caggcggccc gccgggtcag cctcgggtgc
    19741 agtcggtccc aggcccgcac ggtggccttg ccgtagagcc gagtgtcggt gtccgtgacg
    19801 gcttgctcct cgccccaggt ggcgggatcg ctgaagacga actcccggcc gtgcttgggc
    19861 ggccgaccgc ccttggggtc gtagacccgc ggcggggtcg gctggcgcat cagacatcga
    19921 gcccgccgcg gttgaggccg gcatagaggg caccgtggcc ccgacggtgt tcgggtgcca
    19981 gcgcgagatc gaccagcgac cgcaccggtc cgtcggtgca cagcaccgcg tgggtcagct
    20041 cgaacagcgc gtcggcgtgt gcggtcaggc agtcgtagag gtcggtccgg aagcgggaca
    20101 acacggccag ggactcgatg cggacagcgc cgtgcagcga gactcacccg cgcggccttg
    20161 gcatgatcaa cagcgtcccg atcacacaca tgatccgtac cgctgtcgca cggccatcat
    20221 cgactggcag atgccctgac acggaaactc gacgggggcg aatttgaaca cctccgagct
    20281 ccgggtagcg ttcgggttct ccacttcgaa ggagagcgca cttccgtctt cactcgccga
    20341 gctcggaaaa cgttctgctg tcccgtccgg cgatttcacg gtgaaccaca atgcccgccc
    20401 gctgatgcga tagctgccct ggtagatgcc gggacgctcg ctgccgggac ggagccagtg
    20461 agcgatctgc tgcggctccc cgtccgcgga cacataagta acgttcgcag ggtcggtgaa
    20521 gcggagaaat ccgagcgagc tgccgcgtgc tgacatgtag agaccatccc gacgtggaag
    20581 ctgcacaggg ctggacaagg cctgcggtgg ttgaggcttc gaggcgggca cgtcagcagg
    20641 aaggcagggg agcaggtcgc ggagaatcgc aaggagttcg gtgggcgcgt tggtcgactc
    20701 gtagaattcg atcacgtgag cccggacatg aggttcccgg aggctgtaga cgtaccccat
    20761 ggaggcccgc agtgggcggc gcagggcata cgggggttcg tcgggattgt gctgtacgtc
    20821 tgcgcgcagc tcgccacggt agccggacgg aaccacgact tcggtgaggg aatgggtatc
    20881 tggaatttcg agcgccattc tgagattgcc atcccgggcg atgtagtagt cgcgtgcctg
    20941 aactgggcga tatcgccggt tcacctccag ccggcctggg tcccgattca gccagctctt
    21001 cttctcatga cactcgacaa tgtcgaatag gaggtatccg ggctcggcag caggtgcagc
    21061 gagcgcgcgg ttgccgggcc ccgaagagcg gcattcagcg cgtcgccccc gcgctgcaac
    21121 gatcgggcca ccgcgtcatc cgcgctcctg tctcggcagc gaaggaaccc cggcccccct
    21181 tcggcgaagc cccgccacca catggctctg acctgcctgc cgtccggcat cggtccgggc
    21241 catccggccg accgggagcc cggcgggagt tcgtccgtgg atagacgctc cgtcctgccc
    21301 acaaaggagg gctgggcgct gatgccgttc gtccccacct ccgggacgaa gtgctcaccg
    21361 cagcaccgca cactgcacat cggacaggtg gcaagggagt ccactccaca ccagcacgcg
    21421 gtcacggcga gagaccgtag cagggttgca tcggtcgggt aagaacatgc gccagcacac
    21481 catcccccct gctcagcagc cggggggcgg ccgaatccgc gacggccttc ccgacatgga
    21541 cgtcaaacaa caagcccctg acgggcagac tcagcccggc ctcataagcg gcgaccggac
    21601 gaccgcgact gatcccaccg cccacggcca ctcggccagc tgctgttact gacccacact
    21661 cctaggccgg cgtgcagtcc gagccggcct agcggggggc cgtggcgacg acgttggcaa
    21721 gcggacgcac atgagcgccg tcgcccgccc aagaccagct ggcggcaact gacgcgcagc
    21781 cagttccccc cctggggctg gctggcctgg ccgcgatgac gggccccgct gtccgatctc
    21841 tggccctcgg tgcgtggccc ggacctccac ctctgcgacc agtcttcacg gctcttgccg
    21901 ttcggggcca cgttcatccg gggtacgtcg aggatccgtc cgagcacgcg gcagccaaac
    21961 cttcgacggc tacgcgatgt cgcgatgagt tcggccgtct ctgccagtct gtgcatatgc
    22021 cgagtgg
//
