LOCUS       NZ_CP094483            10411 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces murinus strain JS029 chromosome.
ACCESSION   NZ_CP094483
VERSION     NZ_CP094483.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces murinus
  ORGANISM  Streptomyces murinus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Draft genome sequence of Streptomyces sp. JS029
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAR-2022) Agricultural Life Science, Sunchon National
            University, Jungangro 255, Suncheon, Jeonnam 57922, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-MAR-2021
            Assembly Method                   :: Unicycler v. 0.3.1
            Assembly Name                     :: JS029
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 164.82x
            Sequencing Technology             :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028753175.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 03:30:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,582
            CDSs (total)                      :: 7,481
            Genes (coding)                    :: 7,273
            CDSs (with protein)               :: 7,273
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 215
            CDSs (without protein)            :: 208
            Pseudo Genes (ambiguous residues) :: 0 of 215
            Pseudo Genes (frameshifted)       :: 110 of 215
            Pseudo Genes (incomplete)         :: 125 of 215
            Pseudo Genes (internal stop)      :: 20 of 215
            Pseudo Genes (multiple problems)  :: 41 of 215
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:08:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6123415
            Orig. end                         :: 6133826
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP094483.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from National Institute of
            Biological Resources.
FEATURES             Location/Qualifiers
     region          1..10411
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ectoine"
                     /region_number="26"
                     /rules="ectoine_synt"
                     /tool="antismash"
     cand_cluster    1..10411
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10411
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5411](-)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5411)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     gene            complement(508..1278)
                     /locus_tag="ME763_RS27345"
                     /old_locus_tag="ME763_27330"
     CDS             complement(508..1278)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019761328.1"
                     /locus_tag="ME763_RS27345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_27330"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_085564144.1"
                     /transl_table=11
                     /translation="MTAGDAGGAQVKSAVRTVELLEYFAGRPGMHSLATVQEAVGYPKS
                     SLYMLLRTLVELGWVETDATGTRYGIGVRALLVGTSYIDGDEVVAAARPALDRLADDTT
                     ETIHLARLDGTSVVYLATRQSQHYLRPFTRVGRRLPAHSTSLGKAILATYTDDEVRALL
                     PPELPALTEHTLTDRERLIEELRRVRERGFAVDREENTVGLRCFGVALPYRAPARDAIS
                     CSVPVARLTPAHEQTIKDALFEARDRLTLATRRL"
     gene            1361..1885
                     /locus_tag="ME763_RS27350"
                     /old_locus_tag="ME763_27335"
     CDS             1361..1885
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004002240.1"
                     /locus_tag="ME763_RS27350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_27335"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_085564143.1"
                     /transl_table=11
                     /translation="MTSEPTSEPGSTLEIRTALPAEAETIAELHLRARSTYYPDGVPQA
                     ELDWTEAWRGSIERADGRVLCAVEEGRLAGVASFRAPDGAGADTVKLFQFHVDPDRWRG
                     GIGTALHTVCVGEWRAAGRRTAVLDVHVDNLRAQGFYARQGWVPDPENPPAEGDHHLFL
                     RYAVSPEAPGE"
     misc_feature    1944..1957
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            1961..2680
                     /locus_tag="ME763_RS27355"
                     /old_locus_tag="ME763_27340"
     CDS             1961..2680
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007381151.1"
                     /locus_tag="ME763_RS27355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_27340"
                     /product="DsbA family oxidoreductase"
                     /protein_id="WP_085564142.1"
                     /transl_table=11
                     /translation="MRVEIWSDIACPWCYVGKARFEKALAAFPHREDVEVVHRSFELDP
                     GRAKGDVESVLTMLTRKYGMSEAQAEAGEDNLGAQAAAEGLDYRTRGRDHGNTFDMHRL
                     LHLAKERGRQDELIQALYRANFAEERSVFAEGDERLVELATGAGLDAAEVRAVLADPEA
                     YADAVREDEREAAELGANGVPFFVLDRKYGVSGAQPAEVFAQALGQAWGERAPLKLVDQ
                     GDAEACGPDGCAVPPRG"
     gene            2790..3842
                     /locus_tag="ME763_RS27360"
                     /old_locus_tag="ME763_27345"
     CDS             2790..3842
                     /NRPS_PKS="Domain: Aminotran_5 (17-344). E-value: 2.1e-26.
                     Score: 84.6. Matches aSDomain:
                     nrpspksdomains_ME763_RS27360_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004989745.1"
                     /locus_tag="ME763_RS27360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_27345"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_085568450.1"
                     /sec_met_domain="Aminotran_5 (E-value: 3.3e-20, bitscore:
                     71.1, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METFESLVRAEFRPKNTYLNTASSGLLPARTRTALQEAIAIRAEG
                     RPLDPLFEDVERARAAFARLAGVPASRVAAGPSVAAQTGLIAASLPAGAEVLTAEDDFT
                     SVVNPFHVRGDLKVRAVPLERIAESVRPGTALVAVSAAQSADGRVADLPALRAAARTHG
                     ARTYVDFSQAAGWLPIDADGYDFTVATTFKWLLGPHGAAFLVVPEDMGGLTPLLAGWVA
                     AENPWDSCYGPVAELAHSARRFDVSPGLFTYSGVHASLTLIEELGVAAVHAHDLALADR
                     FTQGLARLGHEPLPAPGSAIVSVPGLGAKQAELSRAGIQVSDRAGNLRASFHLYNTAAD
                     VDRLLDVLAG"
     aSDomain        2841..3821
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ME763_RS27360_Aminotran_5.1"
                     /evalue="2.10E-26"
                     /label="ME763_RS27360_Aminotran_5.1"
                     /locus_tag="ME763_RS27360"
                     /protein_end="344"
                     /protein_start="17"
                     /score="84.6"
                     /tool="antismash"
                     /translation="YLNTASSGLLPARTRTALQEAIAIRAEGRPLDPLFEDVERARAAF
                     ARLAGVPASRVAAGPSVAAQTGLIAASLPAGAEVLTAEDDFTSVVNPFHVRGDLKVRAV
                     PLERIAESVRPGTALVAVSAAQSADGRVADLPALRAAARTHGARTYVDFSQAAGWLPID
                     ADGYDFTVATTFKWLLGPHGAAFLVVPEDMGGLTPLLAGWVAAENPWDSCYGPVAELAH
                     SARRFDVSPGLFTYSGVHASLTLIEELGVAAVHAHDLALADRFTQGLARLGHEPLPAPG
                     SAIVSVPGLGAKQAELSRAGIQVSDRAGNLRASFHLYNTAADVDRL"
     gene            complement(4101..4994)
                     /gene="thpD"
                     /locus_tag="ME763_RS27365"
                     /old_locus_tag="ME763_27350"
     CDS             complement(4101..4994)
                     /EC_number="1.14.11.55"
                     /codon_start=1
                     /gene="thpD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007448161.1"
                     /locus_tag="ME763_RS27365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_27350"
                     /product="ectoine hydroxylase"
                     /protein_id="WP_085564141.1"
                     /sec_met_domain="PhyH (E-value: 4.5e-36, bitscore: 123.8,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTATVKDLYPTRGATEVTVPRQDPVVWGSPGSPGPIAAGDLQAF
                     ERDGFLSVDQLIGSDEVEIYRQELDRLVADPAIRFDERSIVEPKSQEIRSVFEVHRISE
                     VFAALVRDERVVGRARQILGSDVYVHQSRINVKPGFGASGFYWHSDFETWHAEDGLPNM
                     RTVSVSIALTENHDTNGGLMIMPGSHRTFLGCAGETPKDNYKKSLQMQDAGTPSDAALT
                     ELAGEHGIKLFTGRPGSATWFDCNCMHGSGDNITPFPRSNVFIVFNSVENTAVEPFAAP
                     VRRPEFIGARDFTPVR"
     gene            complement(5001..5411)
                     /locus_tag="ME763_RS27370"
                     /old_locus_tag="ME763_27355"
     CDS             complement(5001..5411)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009337952.1"
                     /locus_tag="ME763_RS27370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_27355"
                     /product="ectoine synthase"
                     /protein_id="WP_085564140.1"
                     /sec_met_domain="ectoine_synt (E-value: 7.7e-54, bitscore:
                     179.6, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVRSFKDIEGTDRHIKSKSGTWESKRIVLAKERVGFSVHETILY
                     AGTETQMWYANHIEAVVCTKGEAELTDRETGRTYTITPGTMYLLNGHERHTLRVKEDFH
                     CICVFNPPVTGREDHDENGVYPLLTEPEPEEV"
     gene            complement(5466..6737)
                     /gene="ectB"
                     /locus_tag="ME763_RS27375"
                     /old_locus_tag="ME763_27360"
     CDS             complement(5466..6737)
                     /EC_number="2.6.1.76"
                     /GO_function="GO:0045303 - diaminobutyrate-2-oxoglutarate
                     transaminase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (28-366). E-value: 8.3e-74.
                     Score: 240.5. Matches aSDomain:
                     nrpspksdomains_ME763_RS27375_Aminotran_3.1"
                     /codon_start=1
                     /gene="ectB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007381147.1"
                     /locus_tag="ME763_RS27375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_27360"
                     /product="diaminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="WP_085564139.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.7e-77, bitscore:
                     258.9, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITQPDLSVFETLESEVRSYCRGWPTVFDRAQGSRMYDEDGHSY
                     LDFFAGAGSLNYGHNNPVLKRALIDYLSRDGVTHGLDMSTTAKRRFLETFQNLVLRPRD
                     LPYKVMFPGPTGTNAVESALKLARKVKGREAIVSFTNAFHGMSLGSLAVTGNAFKRAGA
                     GIPLVHGTPMPFDNYFDGTVPDFLWFERLLEDQGSGLNKPAAVIVETVQGEGGINVARP
                     EWLRALKELCERQDMLLIVDDIQMGCGRTGAFFSFEESGITPDIVTVSKSISGYGLPMS
                     LCLFRPELDVWEPGEHNGTFRGNNPAFVTAAAALEAYWTDGSAMEKQTRARGEQVEQAL
                     ISITEENLADVKEYRGRGLVWGMEFHDKDRAGRIARRAFELGLLIETSGPESEVVKLLP
                     ALTITPDELDEGLSVLARAVRETV"
     aSDomain        complement(5640..6653)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ME763_RS27375_Aminotran_3.1"
                     /evalue="8.30E-74"
                     /label="ME763_RS27375_Aminotran_3.1"
                     /locus_tag="ME763_RS27375"
                     /protein_end="366"
                     /protein_start="28"
                     /score="240.5"
                     /tool="antismash"
                     /translation="FDRAQGSRMYDEDGHSYLDFFAGAGSLNYGHNNPVLKRALIDYLS
                     RDGVTHGLDMSTTAKRRFLETFQNLVLRPRDLPYKVMFPGPTGTNAVESALKLARKVKG
                     REAIVSFTNAFHGMSLGSLAVTGNAFKRAGAGIPLVHGTPMPFDNYFDGTVPDFLWFER
                     LLEDQGSGLNKPAAVIVETVQGEGGINVARPEWLRALKELCERQDMLLIVDDIQMGCGR
                     TGAFFSFEESGITPDIVTVSKSISGYGLPMSLCLFRPELDVWEPGEHNGTFRGNNPAFV
                     TAAAALEAYWTDGSAMEKQTRARGEQVEQALISITEENLADVKEYRGRGLVWGMEFH"
     gene            complement(6751..7266)
                     /gene="ectA"
                     /locus_tag="ME763_RS27380"
                     /old_locus_tag="ME763_27365"
     CDS             complement(6751..7266)
                     /EC_number="2.3.1.178"
                     /GO_function="GO:0033816 - diaminobutyrate
                     acetyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ectA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004989754.1"
                     /locus_tag="ME763_RS27380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_27365"
                     /product="diaminobutyrate acetyltransferase"
                     /protein_id="WP_085564138.1"
                     /transl_table=11
                     /translation="MTAAPADLLIDRPATADGAALWRLAKDSKTLDLNSSYSYLLWCRD
                     FAGTSAVARGADGTPVGFITGYVRPDRPDTLLVWQVAVDSAHRGHGIAAALLDGLTARL
                     GESGVTRIETTITPGNTASERLFTSYAERHGAHLTREVLFPAELFPDGPHDSEVLYRIG
                     PPADSHAH"
     misc_feature    complement(7291..7300)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.15"
                     /tool="antismash"
     misc_feature    complement(7385..7400)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     misc_feature    complement(7418..7432)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.98"
                     /tool="antismash"
     misc_feature    7446..7462
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.87"
                     /tool="antismash"
     misc_feature    complement(7501..7515)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.1"
                     /tool="antismash"
     misc_feature    7502..7515
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.05"
                     /tool="antismash"
     misc_feature    complement(7505..7520)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.6"
                     /tool="antismash"
     gene            complement(7522..8076)
                     /locus_tag="ME763_RS27385"
                     /old_locus_tag="ME763_27370"
     CDS             complement(7522..8076)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010355555.1"
                     /locus_tag="ME763_RS27385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_27370"
                     /product="DinB family protein"
                     /protein_id="WP_085564137.1"
                     /transl_table=11
                     /translation="MTSDHIPRPDHTSAHPALPDGRPIPLPTGPERPMLESWLDFHRAT
                     LELKCRGLSDGQARAAAAQPSELTLLGLVQHLAEVERTWFQRVLGGLDLPPLFEEESGY
                     GLDPARGLDEALTVWHREIARGRELCAGRPLEATGRIADGPMAGTEVSVRWVLIHLIEE
                     YARHNGHADILRERIDGTTGA"
     misc_feature    complement(8099..8111)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            complement(8158..9258)
                     /locus_tag="ME763_RS27390"
                     /old_locus_tag="ME763_27375"
     CDS             complement(8158..9258)
                     /NRPS_PKS="Domain: Aminotran_5 (73-303). E-value: 1.9e-28.
                     Score: 91.4. Matches aSDomain:
                     nrpspksdomains_ME763_RS27390_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010037833.1"
                     /locus_tag="ME763_RS27390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_27375"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_085564136.1"
                     /sec_met_domain="Aminotran_5 (E-value: 1.1e-21, bitscore:
                     76.0, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHPLLDLPPLTARRFAAIEDRVARLLDTRQDVLITQGEALLPLE
                     GAIRAAAGPGTVALNVITGPYGQTFGDWLRDAGATVYDISVPFHTAVRAEQIRAAFAEH
                     PEIDFVSLVHAEAATGNTNPVAEIGAAVREQGALFYLDAVASVGAEPVLPDAWGVDLCV
                     IGAQKAMGGPAGVSAISVSERAWARMAANPNAPRRSYLSLLDWKERWLDAGRRALPHAP
                     AQLEMLALDACLERIEAAGLDAVTARHRRAAEATRAGASALGGGLEPYVHDAADAAPVA
                     TTLRVPPSLTASDLVAAALAADPALPLAAGGGALAKEMIRVNHYGPDATESAVQASLAA
                     LGTALAAQGAPVDPAAARQAVERVWR"
     aSDomain        complement(8350..9039)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ME763_RS27390_Aminotran_5.1"
                     /evalue="1.90E-28"
                     /label="ME763_RS27390_Aminotran_5.1"
                     /locus_tag="ME763_RS27390"
                     /protein_end="303"
                     /protein_start="73"
                     /score="91.4"
                     /tool="antismash"
                     /translation="LRDAGATVYDISVPFHTAVRAEQIRAAFAEHPEIDFVSLVHAEAA
                     TGNTNPVAEIGAAVREQGALFYLDAVASVGAEPVLPDAWGVDLCVIGAQKAMGGPAGVS
                     AISVSERAWARMAANPNAPRRSYLSLLDWKERWLDAGRRALPHAPAQLEMLALDACLER
                     IEAAGLDAVTARHRRAAEATRAGASALGGGLEPYVHDAADAAPVATTLRVPPSLTASDL
                     VAAALAAD"
     misc_feature    9354..9370
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.94"
                     /tool="antismash"
     misc_feature    9368..9382
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.31"
                     /tool="antismash"
     gene            9417..10259
                     /locus_tag="ME763_RS27395"
                     /old_locus_tag="ME763_27380"
     CDS             9417..10259
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020121392.1"
                     /locus_tag="ME763_RS27395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_27380"
                     /product="basic amino acid ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_085564135.1"
                     /transl_table=11
                     /translation="MKTPFGRRTRLLAATTATAGLVLVVAGCSSGGSGSGQTVAGGVHL
                     AKAGQLTTCTHLPYPPFQSVVDGKVQGFDVSLIDLVAKDLGVKQQIVDTPFENFKTGAF
                     LNSGQCDLAAAGMTITPERAKNVDFSDPYFEATQAVLVAKNSGITSLDGAKGKKLGAQA
                     QTTGEDFAKKKGLDPVSFASSDAVLNGLRTGQVQAVVIDYPVVQGWLKDKANADKFKVV
                     DNLKTGEQYGFTVKKGNKPLLKAINKALKDAKADGTYKKIYEKWIGPYDSSVASPAGS"
ORIGIN
        1 gccccggccg ttggcgaagc cccgggcccg gacggactcg cggaagccgc acttggccag
       61 gacccgcagc gaggcggcgt tgtcggccgc cgcccgcgcg tagagcgggc gctcggggac
      121 ctcggcgagc agggcgcgca gcgcggccgt cgccacgccc cggccccagt gggcgcggtc
      181 gatccagtac gtcacctcgc gctcgccggg ctccccgtag accgccgcgc tgccggccac
      241 ccgcccgtcg gccagcaccg tgcgcagcac gtcacgggag gcgcggatcc gtttgagccg
      301 ggcctcgaag gcgtcccggt cggtcgggtc ctgggggccg aacgcggcca tccgcagggc
      361 caccgggtcg gtcatctgcc ggaagaacaa cggcagatcc tcgtcgtgga cggtccgcag
      421 cgtgatctcc atggagcccg agaatacgac ggtacgaccg ccgtgccgga gcgcggcgcg
      481 cggctcgccg ctgggcccgg cccgtgctca gagcctgcgg gtcgccaggg tcagccggtc
      541 gcgggcctcg aacagcgcgt ccttgatcgt ctgttcatgg gcgggggtca gccgggccac
      601 cggcaccgag cagctgatcg cgtcgcgggc cggggcccgg tacggcaggg ccacgccgaa
      661 gcagcgcagc cccaccgtgt tctcctcgcg gtcgaccgcg aagccccgct cccgcacccg
      721 gcgcagctcc tcgatcagcc gctcccggtc ggtgagggtg tgctcggtga gcgcgggcag
      781 ctccggcggc agcagcgccc gtacctcgtc gtcggtgtac gtggcgagga tcgccttgcc
      841 gagggaggtg gagtgggccg ggaggcggcg cccgacccgg gtgaaggggc gcagatagtg
      901 ctgggactgg cgggtggcga ggtagaccac gctggtgccg tcgagccggg ccagatggat
      961 ggtctcggtg gtgtcgtcgg cgagccggtc cagcgccgga cgggcggcgg ccaccacctc
     1021 gtcgccgtcg atgtacgagg tgcccaccag cagggcccgc accccgatgc cgtaccgcgt
     1081 gcccgtcgcg tccgtctcca cccagcccag ctccacgagg gtgcgcagca acatgtacag
     1141 actggacttg gggtagccga cggcctcctg cacggtcgcg agggagtgca tgccggggcg
     1201 gccggcgaag tactccagca gctcgaccgt ccgtaccgcg gacttgacct gagccccgcc
     1261 cgcgtcgcct gccgtcatcg ccctcgaccc cttcgcctcg acggcgttca gtgtaaagaa
     1321 cgccgggaac cggcggcacg ggcacgacgt cctccgtccc atgaccagtg aaccgaccag
     1381 tgaacccgga agcaccctgg agatccgcac cgcgctgccc gccgaggccg aaaccatcgc
     1441 cgagctgcat ctgcgcgcgc gctcgacgta ctacccggac ggtgtcccgc aggcggagtt
     1501 ggactggacc gaggcatggc gggggtccat cgagcgggcc gacggacggg tgctgtgcgc
     1561 cgtcgaggag ggccggctgg ccggggtcgc ctccttccgg gcgccggacg gagccggcgc
     1621 ggacaccgtc aagctgttcc agttccatgt cgacccggac cgctggcggg gcggtatcgg
     1681 cacggccctg cacacggtct gcgtggggga gtggcgggcg gccgggcggc gcacggccgt
     1741 gctcgacgtc catgtggaca acctgcgggc ccagggcttc tacgcccggc agggctgggt
     1801 gccggacccg gagaacccgc ccgcggaggg ggaccaccat ctgttcctgc ggtacgccgt
     1861 gtcgccggag gcgccggggg aatgaccggc ggcatttgaa tgttcacgta ctcggcgggg
     1921 atcgtctccg cacccgtacg acctggaaag agccgaagac atgcgcgtcg agatctggag
     1981 cgacatcgcc tgcccctggt gctatgtggg caaggcccgc ttcgagaagg cgctcgccgc
     2041 cttcccgcac cgcgaggacg tggaggtggt gcaccgctcc ttcgagctgg accccggccg
     2101 cgccaagggc gatgtcgagt ccgtgctcac catgctgacc aggaagtacg gcatgagcga
     2161 ggcgcaggcc gaggccgggg aggacaacct gggcgcccag gccgccgccg agggcctgga
     2221 ctaccgcacc cggggccgcg accacggcaa caccttcgac atgcaccgcc tgctgcacct
     2281 ggccaaggag cgcggccggc aggacgagct gatccaggcc ctgtaccggg ccaacttcgc
     2341 cgaggagcgg tctgtcttcg ccgagggcga cgagcggctg gtcgagctgg ccaccggagc
     2401 cggtctcgac gcggccgagg tgcgcgcggt gctcgccgac cccgaggcgt acgccgacgc
     2461 ggtgcgcgag gacgagcgcg aggccgccga gctcggtgcg aacggcgtcc ccttcttcgt
     2521 gctcgaccgc aagtacggcg tctccggcgc ccagcccgcc gaggtcttcg cccaggcgct
     2581 cggccaggcc tggggcgagc gcgccccgct gaagctggtc gaccagggcg acgccgaggc
     2641 ctgcggcccg gacggctgcg cggtgccgcc gaggggctga ccgcccgggg caggaacgcc
     2701 aggtcggcgc ggtcgtacaa gaaacccttg gcgcgtcccc gtggaaacgc gcgatggacg
     2761 ggggcctcgc cgacccgcac agtgggctca tggagacctt cgagagcctc gtccgcgccg
     2821 agttccgccc gaagaacacc tatctgaaca ccgcgagcag cggcctgctc ccggcccgta
     2881 cccgcaccgc gctccaggag gcgatcgcga tccgggccga gggccgcccg ctggacccgc
     2941 tgttcgagga cgtcgagcgc gcccgcgccg ccttcgcccg gctggccggg gtcccggcga
     3001 gccgggtggc ggccggtccc tcggtcgccg cgcagacggg tctgatcgcg gcctccctgc
     3061 ccgcgggcgc cgaagtcctc accgccgagg acgacttcac ctccgtggtg aaccccttcc
     3121 atgtgcgcgg cgacctcaag gtgcgcgccg tacccctgga gcggatcgcc gagtcggtgc
     3181 gccccggaac cgcgctggtc gcggtcagcg ccgcgcagtc cgccgacggc cgggtcgccg
     3241 atctgcccgc cctgcgcgcg gcggcccgca cccatggcgc gcgcacctat gtcgacttct
     3301 cccaggccgc cggctggctg ccgatcgacg cggacggcta cgacttcacc gtcgccacca
     3361 ccttcaagtg gctgctcggc ccgcacggcg ccgccttcct cgtcgtcccc gaggacatgg
     3421 gcgggctgac cccgctgctc gcgggctggg tcgcggccga gaacccgtgg gacagctgct
     3481 acggcccggt cgccgaactc gcccactccg cccgccggtt cgacgtcagc cccggtctgt
     3541 tcacctacag cggggtccat gcctcgctca ccctgatcga ggagctgggc gtggccgccg
     3601 tgcacgcgca cgacctggcg ctcgccgacc gtttcacaca ggggctcgcc cggctggggc
     3661 acgagccgct gcccgcgccc ggctcggcga tcgtctccgt gcccggactc ggcgcgaagc
     3721 aggccgagtt gagccgcgcc ggcatccagg tgtccgaccg ggcgggcaat ctgcgcgcgt
     3781 ccttccacct ctacaacacg gcggcggacg tggaccggct gctcgatgtg ctggccggtt
     3841 agggcctctc tttcggatct tgtcggggtc gcggggtctg gcacgcacat ctgcggcgtt
     3901 gtcgtccctc gccgatgctc cgcatcgact cactcctccg ccttgcagct gcacgcacca
     3961 gaccccgctc gggtcagccg agaggggccc ttgcccgtgg ccgacctgat ccgaaagaaa
     4021 ggccctagcc ctgtcgggac atgaccgggc cggggcctcc cgtcccacac gtgaaggccc
     4081 cggcccggtg ctcgaaggcg ctacctcacc ggggtgaagt cgcgcgcgcc gatgaactcc
     4141 ggtcggcgca ccggcgcggc gaacggctcc accgccgtgt tctccacgct gttgaacacg
     4201 atgaagacgt tgctgcgcgg gaacggggtg atgttgtccc cggagccgtg catgcagttg
     4261 cagtcgaacc aggtggccga gcccggcctg ccggtgaaca gcttgatgcc gtgctcgccc
     4321 gccagctcgg tcagcgccgc gtcggagggg gtgcccgcgt cctgcatctg gagcgacttc
     4381 ttgtagttgt ccttgggcgt ctcgcccgcg cagcccagga acgtccggtg cgagcccggc
     4441 atgatcatca ggccgccgtt ggtgtcgtgg ttctcggtca gcgcgatcga gacggacacc
     4501 gtgcgcatgt tcggcagacc gtcctcggcg tgccaggtct cgaagtccga gtgccagtag
     4561 aagccgctcg cgccgaagcc cggcttgacg ttgatccgcg actggtggac gtacacgtcc
     4621 gagccgagga tctggcgggc ccggccgacc acgcgctcgt cgcgcaccag ggccgcgaac
     4681 acctcgctga tccggtgcac ctcgaagacc gagcggatct cctgggactt cggctccacg
     4741 atggagcgct cgtcgaagcg gatcgccggg tcggcgacca gccggtccag ctcctgccgg
     4801 tagatctcga cctcgtcgga gccgatcagc tggtcgacgg agaggaagcc gtcacgctcg
     4861 aacgcctgga gatcgcccgc cgcgatcggt cccggtgagc cgggcgaacc ccagacgacc
     4921 ggatcctggc gggggacggt cacctcggtg gcaccacggg tcgggtagag gtccttcacg
     4981 gtggcggtgg tcatggtcgc tcacacctcc tcgggctcgg gctccgtgag cagcgggtag
     5041 acgccgttct cgtcgtggtc ctcccgtccg gtgacgggcg ggttgaacac gcagatgcag
     5101 tggaagtcct ccttgacacg cagcgtgtgc cgctcgtgcc cgttcaggag gtacatggtg
     5161 ccgggcgtga tggtgtacgt ccgcccggtc tcgcggtcgg tcagttcggc ctcgcccttg
     5221 gtgcagacga cggcctcgat gtggttggcg taccacatct gggtctcggt ccccgcgtac
     5281 aggatggtct cgtgcacgga gaagccgacc cgctccttgg ccaggacgat gcgcttgctc
     5341 tcccaggtgc ccgacttcga cttgatgtgc cggtcggtgc cttcgatgtc cttgaacgat
     5401 cggacgatca cggtggtgct tcctcctggt cggacggtgc ggtcagacgg tgtgcttcag
     5461 atggttcaga cggtttcccg gacggcgcgg gcaaggacgc tcaggccctc gtccagctcg
     5521 tcgggggtga tggtcagggc cggcagcagc ttgacgacct cgctctccgg ccccgaggtc
     5581 tcgatgagca ggcccagttc gaaggcccgc cgcgcgatgc gcccggcacg gtccttgtcg
     5641 tggaactcca tgccccacac cagcccgcgc ccgcggtact ccttgacgtc ggcgaggttc
     5701 tcctcggtga tggagatcag cgcctgctcg acctgctcgc cgcgggcccg ggtctgcttc
     5761 tccatggccg agccgtcggt ccagtacgcc tccagggccg cggcggcggt gacgaacgcg
     5821 gggttgttgc cgcggaaggt gccgttgtgc tcgcccggct cccagacgtc cagctcgggc
     5881 cggaacaggc acagcgacat cggcaggccg tagccgctga tggacttcga caccgtgacg
     5941 atgtcggggg tgatcccgga ctcctcgaag gagaagaagg cgccggtacg gccgcagccc
     6001 atctggatgt cgtcgacgat cagcagcatg tcctgccgct cgcacagctc cttgagcgcg
     6061 cgcagccact cgggccgggc cacattgatg ccgccctcgc cctgcacggt ctccacgatc
     6121 accgcggcgg gcttgttcag accggagccc tggtcctcga ggagccgctc gaaccacagg
     6181 aagtccggga cggtgccgtc gaagtagttg tcgaacggca tcggggtgcc gtgcaccagc
     6241 gggatgccgg cgccggcccg cttgaaggcg ttgccggtca ccgcgagcga gcccagggac
     6301 atgccgtgga aggcgttggt gaaggacacg atggcctcgc ggcccttcac cttccgggcc
     6361 agcttcagcg ccgactccac ggcgttggtg ccggtcgggc ccgggaacat gaccttgtac
     6421 ggcaggtcgc gcgggcgcag caccaggttc tggaaggtct ccaggaagcg gcgcttggcc
     6481 gtggtcgaca tgtccaggcc gtgggtgacc ccgtcccggg acagatagtc gatcagcgcc
     6541 cgtttgagta ccgggttgtt gtggccgtag ttgagtgatc cggccccggc gaagaagtcg
     6601 aggtaggagt ggccgtcctc gtcgtacatc cggctgccct gcgcgcggtc gaacacggtg
     6661 ggccagccgc ggcagtagct gcgcacctcg gactccaggg tctcgaagac gctgaggtcg
     6721 ggctgggtga tggtcacggt gattcgctcc tcagtgggcg tgggaatcgg ccggcgggcc
     6781 gatgcggtag aggacttcgg agtcgtgcgg gccgtccggg aacagctcgg cggggaacag
     6841 cacctcgcgg gtgaggtgcg cgccgtgccg ctcggcgtac gaggtgaaca gccgctcgga
     6901 ggcggtgttg ccgggcgtga tggtggtctc gatccgggtg acgccggact cgccgagccg
     6961 cgcggtcagt ccgtccagca gggcggcggc gatgccgtgg ccccgatggg cggagtccac
     7021 ggcgacctgc cagacgagca gggtgtccgg gcggtcgggc cgcacgtacc cggtgatgaa
     7081 tccgacgggt gtgccgtccg caccgcgcgc caccgccgag gtgccggcga agtcccggca
     7141 ccacagcaga tagctgtagg acgagttgag atcgagcgtt ttcgagtcct tggcgaggcg
     7201 ccagagcgcg gcgccgtcgg ccgttgccgg tcggtctatg agcaggtctg cgggtgcggc
     7261 agtcatgcgg cacgaattta gcgaggcaaa ttaaaaaatg cacgaccgcc ggtgcgacgc
     7321 ggtccggaac ggtgtgctga atgtctgact tgcaccacgg caaagtgggg caaaatcccc
     7381 tcattgtggg gtgtgtcaca ccactgaaac cgtcagaaat ctcctggaaa actggcccgt
     7441 ttagccgcgc aaaaagcggg cagaagacta tgggaagcta ccgtccggga aattggcggg
     7501 aattgtgaaa ctaaattgaa ttcaagctcc ggtggtgccg tctattcgtt cgcggagaat
     7561 gtccgcgtgc ccgttgtggc gggcgtactc ctcgatgagg tggatcagca cccagcgcac
     7621 actgacctcc gtcccggcca tcggaccgtc cgcgatccgg ccggtggcct ccagcggccg
     7681 cccggcgcac agctcgcggc cgcgcgcgat ctcccggtgc cagacggtca gcgcctcgtc
     7741 cagcccacgc gccggatcca ggccgtaccc ggactcctcc tcgaacagcg gcggcaggtc
     7801 gaggccgccc agcacccgct ggaaccaggt ccgctcgacc tccgcgagat gctgcaccag
     7861 gcccagcagg gtcagctccg acggctgcgc cgcggcggcc ctcgcctgcc cgtcggacag
     7921 accccggcac ttcagctcca gcgtggcccg gtggaagtcc agccagctct ccagcatggg
     7981 gcgctcgggg ccggtcggca gggggatcgg gcggccgtcg gggagggccg ggtgcgcgga
     8041 tgtgtggtcc ggccgcggga tgtgatcact ggtcatgggc gcagcatggc agccgggtgt
     8101 gacaacggcc cgcgcctcgg ggcgcgggcc gtcgtggtgt tcaccggtcc gtggcggcta
     8161 ccgccagacc cgctccacgg cctgccgggc ggccgccggg tccaccggcg cgccctgggc
     8221 ggcgagggcc gtgcccaggg cggccagcga ggcctggacg gcggactcgg tggcgtcggg
     8281 gccgtagtgg ttgacccgga tcatctcctt ggccagggcg ccgccgcccg cggccagcgg
     8341 aagggcgggg tcggcggcca gcgcggcggc gaccaggtcg gaggccgtga gcgacggcgg
     8401 gacgcgcagg gtcgtggcga ccggggcggc gtccgcggcg tcgtggacat acggctccag
     8461 gccgccgccg agggccgagg cacccgcccg ggtggcctcg gccgcgcggc ggtggcgggc
     8521 cgtcaccgcg tccaggccgg ccgcctcgat ccgctccaga caggcgtcca gcgccagcat
     8581 ctccagctgc gccggggcgt gcggcagggc ccgtcggccg gcgtccagcc agcgctcctt
     8641 ccagtccagc agggagaggt aggagcggcg cggcgcgttc gggttcgccg ccatccgggc
     8701 ccaggcacgc tcgctcaccg agatcgccga gacccccgcc gggccgccca tcgccttctg
     8761 cgcgccgatc acgcacaggt ccacgcccca cgcgtccggc agcaccggct cggcgcccac
     8821 cgaggcgacc gcgtccagat agaacagcgc gccctgctcc cgcaccgccg caccgatctc
     8881 cgcgaccggg ttggtgttgc cggtcgccgc ctccgcgtgc accagcgaga cgaagtcgat
     8941 ctccgggtgc tcggcgaacg cggcacggat ctgctcggcc cgtaccgccg tgtggaaggg
     9001 gaccgagatg tcgtacacgg tcgcgccggc gtcccgcagc cagtcgccga aggtctgccc
     9061 gtaggggccg gtgatcacgt tcagggccac cgtgcccgga ccggcggcgg cgcggatcgc
     9121 gccctccagc ggcagcagcg cctcgccctg ggtgatcagg acgtcctgcc gggtgtccag
     9181 cagccgggcc acccggtcct cgatcgcggc gaagcgccgc gcggtcagcg ggggcaggtc
     9241 gaggaggggg tgcgtcacgg cggtgctctc tcttcgtcgg gcggttcgca ggggtcacgg
     9301 cggcctgctc cccccgatct taggtccagg ccccccaaga ccatgggttt ggtttgagat
     9361 acccaaacat ttccttataa tcggaaccta tcgttccccc ctcaggagac tcccccatga
     9421 aaacgccctt cggacgccgg acccgcctgc tggccgccac caccgcgacc gcgggcctcg
     9481 tgctcgtcgt ggcgggctgc tcctccggcg gctcggggag cggccagacc gtggccggcg
     9541 gggtccacct cgccaaggcc gggcagctca ccacctgcac ccacctgccc tatccgccgt
     9601 tccagtcggt ggtcgacggc aaggtgcagg gcttcgacgt ctccctgatc gacctggtcg
     9661 ccaaggacct cggcgtcaag cagcagatcg tggacacgcc gttcgagaac ttcaagaccg
     9721 gcgccttcct gaactccggc cagtgcgacc tggccgccgc cggtatgacg atcacccccg
     9781 agcgcgcgaa gaacgtcgac ttctccgacc cgtacttcga ggccacccag gccgtgctgg
     9841 tcgccaagaa cagcgggatc acctcgctcg acggcgccaa gggcaagaag ctcggcgccc
     9901 aggcgcagac caccggtgag gacttcgcca agaagaaggg cctcgacccg gtctccttcg
     9961 cctcctccga cgccgtcctc aacggtctgc gcaccggcca ggtccaggcc gtcgtcatcg
    10021 actacccggt ggtccagggc tggctgaagg acaaggccaa cgcggacaag ttcaaggtgg
    10081 tcgacaacct gaagaccggc gagcagtacg gcttcacggt caagaagggc aacaagcccc
    10141 tgctgaaggc catcaacaag gctctcaagg acgccaaggc cgacggcacc tacaagaaga
    10201 tctacgagaa gtggatcggc ccgtacgact cctccgtcgc ctccccggcc ggttcctgac
    10261 cccatggccg acacggacac cggcatccag ccgaagcgca cggggctgac gcgcacgcag
    10321 aagcgcaagc tctcgcgcgg cgcccagtac gccgtcctcg ccgccgcggt gatcgccttc
    10381 gcgctcaccg cggactgggg gcggctccag a
//
