LOCUS       NZ_CP094483            10327 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces murinus strain JS029 chromosome.
ACCESSION   NZ_CP094483
VERSION     NZ_CP094483.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces murinus
  ORGANISM  Streptomyces murinus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Draft genome sequence of Streptomyces sp. JS029
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAR-2022) Agricultural Life Science, Sunchon National
            University, Jungangro 255, Suncheon, Jeonnam 57922, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-MAR-2021
            Assembly Method                   :: Unicycler v. 0.3.1
            Assembly Name                     :: JS029
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 164.82x
            Sequencing Technology             :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028753175.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 03:30:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,582
            CDSs (total)                      :: 7,481
            Genes (coding)                    :: 7,273
            CDSs (with protein)               :: 7,273
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 215
            CDSs (without protein)            :: 208
            Pseudo Genes (ambiguous residues) :: 0 of 215
            Pseudo Genes (frameshifted)       :: 110 of 215
            Pseudo Genes (incomplete)         :: 125 of 215
            Pseudo Genes (internal stop)      :: 20 of 215
            Pseudo Genes (multiple problems)  :: 41 of 215
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:08:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5204695
            Orig. end                         :: >5215022
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP094483.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from National Institute of
            Biological Resources.
FEATURES             Location/Qualifiers
     region          1..>10327
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="melanin"
                     /region_number="24"
                     /rules="melC"
                     /tool="antismash"
     cand_cluster    1..>10327
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="melC"
                     /kind="single"
                     /product="melanin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..>10327
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:>5327](+)"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..>5327
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="1"
     gene            260..487
                     /locus_tag="ME763_RS23120"
                     /old_locus_tag="ME763_23115"
     CDS             260..487
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568399.1"
                     /locus_tag="ME763_RS23120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_23115"
                     /product="chaplin"
                     /protein_id="WP_085564798.1"
                     /transl_table=11
                     /translation="MKKSAAVVAGALLALGGAAPAFADSGAGAVAANSPGVLSGNVIQI
                     PVHVPVNVCGDSVDILALLNPAFGNTCANG"
     misc_feature    618..636
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 24.04"
                     /tool="antismash"
     gene            619..1368
                     /locus_tag="ME763_RS23125"
                     /old_locus_tag="ME763_23120"
     CDS             619..1368
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672819.1"
                     /locus_tag="ME763_RS23125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_23120"
                     /product="chaplin family protein"
                     /protein_id="WP_085564797.1"
                     /transl_table=11
                     /translation="MRQTLSKGMVVAAAAATGVLSLYGTAALADSNAQSLAQGSPGVLS
                     GNSIQVPVHVPVNVCGNSVDVAALLNPAFGNSCANVGHSVTPRPTGYGNDSYGHDAYGH
                     DDPTPTPTSYGHDDPTPPVSYGKPDPTPTPTSYGHDDPTPPPYGSPEPTPTPTSYGSDE
                     PTPTPTSYGSDEPTPPSSYGSDEPTPPSSYGSDEPTPPGSYGNDEPPTLPHTGGNAKAM
                     MATSAASAALIMAGAVLYRRGRTAARR"
     gene            1585..1824
                     /locus_tag="ME763_RS23130"
                     /old_locus_tag="ME763_23125"
     CDS             1585..1824
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568410.1"
                     /locus_tag="ME763_RS23130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_23125"
                     /product="chaplin"
                     /protein_id="WP_085564796.1"
                     /transl_table=11
                     /translation="MSRIAKGLVLTSAAVAAVAGAAGAAAASSGADGVAANSPGVASGN
                     VIQVPVHVPVNVCGDSIDVIGLLNPAFGNTCVNG"
     gene            2023..3006
                     /locus_tag="ME763_RS23135"
                     /old_locus_tag="ME763_23130"
     CDS             2023..3006
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS23135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ME763_23130"
                     /product="hypothetical protein"
                     /protein_id="WP_274506459.1"
                     /transl_table=11
                     /translation="MRALPARRLASTALSAAVIAALTGPVAVAVDTARGHGDAPAAQAA
                     LPGAATLLAQVRALDHAGALPKPVAELLDRSLTEGRLPAAEAERLGDAAKQAVVQAAAE
                     GTLGGAKAPGEPTTPAAPGVAGEPTTPAAPEVPADPTAAGKPTTPADAGAPAPAAPPAA
                     PAVAVVPADPAQAATPEAAASPATSPAAPAAPAVPADAATPAAPSASASVPSGAESQSA
                     LPTPSASPAVALSPAPQGVARSVPGARDLVGDVLAAVDALVKAVVSDVDQVVATANALV
                     AQLLAALPGTGLPTPTATPTPTTPTTLPSVAALPSTPALPTTPATG"
     gene            3138..3428
                     /locus_tag="ME763_RS23140"
                     /old_locus_tag="ME763_23135"
     CDS             3138..3428
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136064.1"
                     /locus_tag="ME763_RS23140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_23135"
                     /product="hypothetical protein"
                     /protein_id="WP_037651691.1"
                     /transl_table=11
                     /translation="MKSLKAAAVLAGSVALAGVAAPAFAYNATDLTPSSLNGAVNQLAK
                     GDFTLRDVMPLQHQSNALDTEDKDSVLHSVKGATTALNQHNPLLGGLPLQS"
     gene            3585..4076
                     /locus_tag="ME763_RS23145"
                     /old_locus_tag="ME763_23140"
     CDS             3585..4076
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019065676.1"
                     /locus_tag="ME763_RS23145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_23140"
                     /product="DUF5949 family protein"
                     /protein_id="WP_085564794.1"
                     /transl_table=11
                     /translation="MTSTPTELRPADLGTLVVLPWSGAAPDGTDMPYLLAYSLGDAAGG
                     PQVTAVAVEQLLVSNGLPVGGDLVDGTYRPSLPITLLVEAGQAVVRMPRLIAQAPAPPE
                     WLAAVRARGFAYLVFTTRAWPEGAPGRIVQPAALAAFAGAPETLHAAAHVVLPATSLRG
                     "
     gene            4306..4809
                     /locus_tag="ME763_RS23150"
                     /old_locus_tag="ME763_23145"
     CDS             4306..4809
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003976098.1"
                     /locus_tag="ME763_RS23150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_23145"
                     /product="hypothetical protein"
                     /protein_id="WP_085564793.1"
                     /transl_table=11
                     /translation="MKPTTRGTLAAVLTGVAAAASATAPAAAAGAVPVPVPLQGVSHSL
                     GTRMPEATLEMPLLTPGAPDGPRYVTGRLLPEPILPRLPITGTLPGADLRAPLPHPLGD
                     RLGLDAPAADLHTAGPGLNLVAPLTAPDPDLFGLPAPRLPEAGLLAPALRTVAGGDLGV
                     GPAR"
     gene            5001..>5327
                     /locus_tag="ME763_RS23155"
                     /old_locus_tag="ME763_23150"
                     /pseudo=""
     CDS             5001..>5327
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     melanin: melC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568414.1"
                     /locus_tag="ME763_RS23155"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_23150"
                     /product="tyrosinase cofactor"
                     /pseudo=""
                     /sec_met_domain="melC (E-value: 1.5e-44, bitscore: 150.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGLLSCAAALALAPVVAASRPVPPAAGGDSFDETYRGRRIQGVR
                     LPEAGRSTSDDAWRITIDGRPLHLMRRADGTWLSMVDHYTSYRTPLEAARAAVDELGPG
                     QRLSD"
     gene            5494..6360
                     /locus_tag="ME763_RS23160"
                     /old_locus_tag="ME763_23155"
     CDS             5494..6360
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019325459.1"
                     /locus_tag="ME763_RS23160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_23155"
                     /product="tyrosinase family protein"
                     /protein_id="WP_085564791.1"
                     /transl_table=11
                     /translation="MAYVRKNAGALTATERKRFVDAVLEVKRRGEYDEFVRTHVAYFAA
                     DGETQLRTAHMAPSFLPWHRRFLLDMEDALRRVDSSVTLPYWDWTRDRTATSVPWTKDL
                     LGGNGRRSDQQVTTGPFAYSTGNWAIKVGVTDGRYLTRDLGRAASPIQLPTKDDVSWAL
                     NDPVYDVQPWDSTVTQGFRNKLEGWGTGSGSASWHNHNRVHRWVGGAMLGAASVNDPVF
                     WLHHAYLDMQWERWQGAHSSHRYLPAAPPGTGDAQHGRVVARHDKLPPWSDTPDQLEDM
                     SGVYRYE"
     gene            complement(6492..6785)
                     /locus_tag="ME763_RS23165"
                     /old_locus_tag="ME763_23160"
     CDS             complement(6492..6785)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568416.1"
                     /locus_tag="ME763_RS23165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_23160"
                     /product="chaplin"
                     /protein_id="WP_085564790.1"
                     /transl_table=11
                     /translation="MSRIAKAAAVALGTGAVVIGGAGLALADAGAEGAAVGSPGVLSGN
                     VIQVPVNIPVNVCGDSVDVIGLLNPAFGNTCVNQGGTLAQPSNGYGNSSYGG"
     gene            complement(6925..7884)
                     /locus_tag="ME763_RS23170"
                     /old_locus_tag="ME763_23165"
     CDS             complement(6925..7884)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672797.1"
                     /locus_tag="ME763_RS23170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_23165"
                     /product="D-2-hydroxyacid dehydrogenase family protein"
                     /protein_id="WP_085564789.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 6.7e-54, bitscore:
                     180.6, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLRCAVLDDFQGVAVESADWSVLGDAVEVVSLRTHLADEDALAT
                     ALAEYDIVVTLRERVGFPGSLLARLPRLRLIVATGMRNTVIDYAAAEKYGVTVCGTQSS
                     GTPPVELTWALLLGLARGIVQENTALRTGGPWQSTVGADLHGARLGVLGLGRIGGKVAR
                     VGLAFGMRVAAWSPRLTEERAAAAGVELAASKEELLAENDFVSVHVPGGDRTRGLVGAA
                     ELALLKPTAYLINTSRASVVDQDALLAALHEGRIAGAGIDVFDIEPLPADHPMRTAPRL
                     LATPHLGYVSAANYRTYFTQAVEDIQAYLAKSPVRQLP"
     misc_feature    7919..7928
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            complement(7962..9080)
                     /locus_tag="ME763_RS23175"
                     /old_locus_tag="ME763_23170"
     CDS             complement(7962..9080)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012745.4"
                     /locus_tag="ME763_RS23175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_23170"
                     /product="glycosyltransferase"
                     /protein_id="WP_085564788.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 8e-16, bitscore:
                     57.1, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASVCLNMIVKNEAPTIRKCLESVRPLVDTWVIVDTGSTDGTQEV
                     IRDCFKDFPGELHEREWKGFDGSRSEAIELARGSADYLLFIDADDEMRIRPGFRMPELT
                     LDAYNIALHDGPVVHWRMALVATRLPWRYEGVLHEYITCDAPHSTGTLEGAHILTVGGG
                     ARLRDEGKREKYLRDAEILAKALVEEPDNARYAFYLAQSWRDAEEPEKALAAYDRRAEM
                     AGWVEETYCAKLYAARLAVQLKRPAGELIDRYLRAYESRPSRIEAIGDLARLCRLEGRW
                     PLAHLFAARAAGIPRPEDILFVEMSWHEWRALDELAVASYWIGDYEKSREYCTRLLDGG
                     KVPEGERARIAANLEFAQGKSATSAPVAPTPA"
     misc_feature    9050..9064
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.98"
                     /tool="antismash"
     gene            complement(9530..9778)
                     /locus_tag="ME763_RS23180"
                     /old_locus_tag="ME763_23175"
     CDS             complement(9530..9778)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087126.1"
                     /locus_tag="ME763_RS23180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_23175"
                     /product="hypothetical protein"
                     /protein_id="WP_085564787.1"
                     /transl_table=11
                     /translation="MTTSPDRVGSREDLAAFVRSLRLDHAEKGVSWENADLSSFLEALA
                     AWIDDADGWYGNTGRDLPPGGDWAFFAQALRAATMYE"
ORIGIN
        1 gggcgccgca ccgattttcc ggtgcggcgc ccggacggtt tcttcgttct tcccgaagaa
       61 gcacctatcc gttaatcgtc caaggtgtca attctacggg ggcgttcgag tgaattaggg
      121 ggcccagcac gttccagggt ttctccggct gtctatccct cgttttacaa cctgccggtc
      181 atggtgcgag ccgttcaagg ctgtgctcgc tcggtttcga ccgctcatag gggcatgacc
      241 gtcagagaag ggaaaattca tgaagaagag cgctgctgtc gtcgccggtg ccctcctggc
      301 gctgggcggg gccgcccccg ccttcgccga ctccggggcc ggggccgtcg ccgccaactc
      361 cccgggtgtg ctctccggca acgtgatcca gatccccgtg cacgttccgg tcaacgtgtg
      421 cggcgactcc gtcgacatcc tcgctctgct gaacccggcg ttcggcaaca cctgcgccaa
      481 cggctgacgt tcggtaccca ccgcacgcca gcccgccggc tgcgtacagg ccggtcccgg
      541 accgtcgatc catagacctt ttggcccggg gccggctttt ccacatctcc gagcagttcg
      601 agtaggaaga ctacgagatt gcgacagacc ctcagcaagg gcatggtcgt ggccgcagct
      661 gccgcgaccg gcgtgctttc gttgtacggc acggccgcgc tcgccgactc caacgcgcag
      721 tcactggccc agggttcacc gggcgtgctg tccggcaaca gcatccaggt cccggtgcac
      781 gtgccggtca atgtctgcgg caactccgtg gacgtggccg cgctgctgaa ccccgcgttc
      841 ggcaactcct gtgccaatgt cggccattcg gtcaccccgc gccccaccgg ttacggcaac
      901 gactcgtacg gccatgacgc gtacggtcac gacgacccga cgcccacgcc cacgtcgtac
      961 ggtcacgacg acccgacccc gccggtctcc tacggcaagc cggacccgac gccgaccccg
     1021 acgtcgtacg gccatgacga ccccacgccg ccgccgtacg gcagccccga gccgacgccg
     1081 acccccacgt cgtacggcag cgacgagccc accccgaccc ccacgtccta cgggagcgac
     1141 gagcccacgc cgccctcctc ctacgggagc gacgagccga ccccgccgtc ctcctacggc
     1201 agtgacgagc cgaccccgcc cggttcgtac ggcaacgacg agccgccgac cctgccgcac
     1261 accggtggca acgccaaggc catgatggcg acatcggccg ccagcgccgc gctgatcatg
     1321 gcgggtgcgg tgctgtaccg ccgcggccgg acggccgccc gtcggtgatc tgccgggtgc
     1381 cggaccccga gcgtccggca cccgccgccc aggacccccg cgcggatgcg tgcgggggtt
     1441 ttcggcatgg gcggccacgt cccctccggg cggcctccgt cgcacatcac ccctttggcg
     1501 gcacaacccg ggggagcggg acgcgttgac acaacgccgg gcagtcgccc ggatgtttgt
     1561 gtctatttca aggagcacct ctccatgtcg cgtatcgcga agggtctggt tctgacctct
     1621 gccgccgtcg cggccgtcgc cggcgccgcc ggtgccgccg ccgcctcctc cggcgcggac
     1681 ggcgttgccg ccaactcgcc cggtgtcgcc tcgggcaatg tcattcaggt cccggtccac
     1741 gtcccggtca acgtctgcgg tgacagcatc gacgtcatcg gtctgctgaa cccggcgttc
     1801 ggcaacacct gcgtcaacgg ctgacgtccg gggcacacac cccttcgacc ggccgtccac
     1861 tccgcgcatc cgtcgcggcg gtgggcggcc ggttctcgtg tcccccggtc ggggcagggg
     1921 cgggcccgga cggggcatgt ggcccagtga gcggttgcgg ggcggatggg gcgaactgac
     1981 ggtgggcttt cagaccccga agcccagccg aaaggaaccc ccatgcgtgc tctgcccgca
     2041 cggcgcctcg cgtccaccgc cctcagcgcc gccgtcatcg ccgcgctcac cggcccggtc
     2101 gccgtcgccg tcgacaccgc gcgaggccat ggcgacgccc ccgccgccca ggccgccctg
     2161 cccggcgccg cgacactcct cgcccaggtc agagccctgg atcacgcggg cgccctgccc
     2221 aagccggtcg ccgaactgct cgaccgctca ctgacggagg gccgactgcc cgcggcggag
     2281 gccgagcgac tcggcgacgc ggcgaagcag gccgtcgtac aggcggcggc ggagggcaca
     2341 ctcggcgggg cgaaggcccc cggtgagccg acgacacccg cggctccggg ggttgccggt
     2401 gagccgacga cgcctgcggc gccggaggtg cccgccgacc cgacggccgc cgggaagccg
     2461 acgacgcccg ccgacgcggg ggcacccgcg ccggccgcgc cgcccgcggc gcctgccgtg
     2521 gccgtcgtac ccgccgatcc ggcccaggcg gcgactcccg aagccgccgc gagcccggcc
     2581 accagcccgg cggccccggc ggccccggcc gtcccggccg acgcggccac gcccgccgct
     2641 ccttcggcat ccgcctcggt cccctcgggg gccgagtccc agtcggcgct gcccacgccg
     2701 tccgcgtcac ccgccgtggc gctcagcccg gccccgcagg gcgtcgcccg cagcgtgccc
     2761 ggcgcccgtg acctcgtcgg cgatgtgctg gccgcggtgg acgccctggt gaaggcggtc
     2821 gtctccgacg tcgaccaggt ggtcgccacc gccaacgccc tggtcgccca gctgctcgcc
     2881 gccctccccg gcaccggcct gccgaccccc accgccaccc cgacccccac caccccgacg
     2941 acactcccga gcgtggccgc cctgccgagc acaccggcgc tcccgaccac gcccgcgacc
     3001 ggctgacccc gaccggtctc caggaccgcc cgaccgtccc tttccggccg aggcatgttc
     3061 atatgtcttc tcgaccatgg ggtttccgcc ccgccacggc gctcgttgga cacgtcgttg
     3121 ccgaagaaag gaacacgatg aagtccctga aggctgccgc cgtcctggcc ggttccgttg
     3181 ccctcgccgg cgtcgccgcg cccgcgttcg cctacaacgc caccgacctg acgccctcca
     3241 gcctcaacgg cgccgtcaac cagctcgcca agggtgactt caccctgcgg gacgtgatgc
     3301 cgctccagca ccagtcgaac gccctcgaca ccgaggacaa ggactccgtg ctgcactcgg
     3361 tcaagggcgc caccaccgcg ctgaaccagc acaacccgct gctcggtggc ctgcctttgc
     3421 agagctgaca ccccctgcgc gaccggggcc ggtaccgcat ccgcggtgcc ggccccgccc
     3481 ctttcgaggc cgcttccctc gttcgtgtgg agccccccgg tccactggtc cggacgggtg
     3541 agaagccgcc gggccgcccc cgggcgcgtc gatatggtcg cgcggtgacc tcaaccccca
     3601 cggaactgcg ccccgccgac ctcggcacgc tggtcgtgct gccctggagc ggcgcggccc
     3661 ccgacggcac cgacatgccc tacctgctgg cctactccct gggggacgcc gcgggcggcc
     3721 cccaggtcac cgcggtcgcg gtcgagcagc tgctggtgag caacggactg ccggtcggcg
     3781 gcgacctggt cgacggcacc taccggccta gcctccccat caccctgctg gtggaggccg
     3841 gccaggccgt cgtacggatg ccgcggctga tcgcgcaggc ccccgcgccg ccggagtggc
     3901 tcgccgccgt ccgggcccgc ggcttcgcct atctggtgtt caccacccgc gcctggcccg
     3961 agggcgcgcc cggcaggatc gtgcagccgg ccgcgctggc cgcgttcgcc ggcgccccgg
     4021 agaccctgca cgccgccgcg catgtcgtac tgccggccac cagcctgcgc ggctgacggc
     4081 agggacgagg gccggggcct cggcatggcg tgacgtgccg gtgagcgtgc acggccggtc
     4141 ggtggcgtgt gcgaccggcc gaccggccga ccgctcatga agatgaccag ccgactatta
     4201 cggcagccgg gggaattgtc gcgccgcccc cgttctccgt cccggccagg ccagttacgc
     4261 ggtacggacg ccgaactccc gcacccggaa agggccgtat ccgagatgaa gccgaccacc
     4321 cgaggaaccc tcgccgccgt gctgaccggc gtcgcggccg ccgcgagcgc gaccgccccc
     4381 gccgccgcgg ccggcgccgt ccccgtgccc gtaccgctcc agggcgtctc ccactccctc
     4441 ggcacgcgga tgcccgaggc cacgctcgag atgccgctgc tgaccccggg cgcgcccgac
     4501 gggccgcgct atgtcaccgg ccggctgctg cccgagccga tcctgccgag gctgccgatc
     4561 acggggacgc tgcccggcgc cgatctgcgg gcgccgctgc cgcatccgct cggtgaccgg
     4621 ctcggcctcg acgcccccgc cgccgacctg cacaccgccg gacccggtct gaacctggtc
     4681 gctcctctca ccgcgcccga cccggacctg ttcggcctgc ccgctccccg gctccccgag
     4741 gccggcctgc tcgccccggc gctgcgcacc gtcgccggcg gcgacctggg cgtgggcccg
     4801 gcccggtaac ccgcagggct ccctcaccag cgccgttcgg ccgtacgccg gtgacccggc
     4861 ccctccttgt ccgttagcgg gtacgacatc tgttcccgga cgaggagagt gcgatggtcg
     4921 acggcgacga cgcagctgcg gcgggcgcga cagagcaggt cagagcggat acgacggccg
     4981 gtcctgggcg gcggcgggtg atgcgggggc tgctgtcctg cgccgccgcc ctcgccctcg
     5041 cgccggttgt cgccgcctcc cggccggtgc ccccggccgc cggcggtgac tccttcgacg
     5101 agacgtaccg gggccggcgc atccagggcg tccggctgcc ggaggccggc cgcagcacgt
     5161 ccgacgacgc ctggcggatc accatcgacg gccgcccgct gcatctgatg cggcgggccg
     5221 acggcacctg gctgagcatg gtcgaccact acacgtcgta ccgcacaccc ctggaggcgg
     5281 cgcgggccgc ggtggacgaa ctcggccccg gccagcggct cagcgacctc gccccaaacc
     5341 cgctggacgg catgctgccc gacggcgtca aggacatgat gggccgcatg ggcctgaccg
     5401 tggacacggg cggcatgggc ggcatggaca tgggcggcag cggcggaacg ggtgcgcccg
     5461 tcccggacat gggcatgggg acggggggcc ggcatggcgt acgtgcgtaa gaacgccgga
     5521 gccctcaccg cgaccgagcg gaaacgattc gtggacgccg tactggaggt caagaggcgc
     5581 ggggagtacg acgagttcgt gcgcacccac gtcgcctact tcgccgccga cggtgagacc
     5641 caactgcgca ccgcccacat ggcgccgtcc ttcctgccct ggcaccgccg gttcctgctg
     5701 gacatggagg acgcgctgcg ccgcgtcgac tcctcggtga ccctgccgta ctgggattgg
     5761 acccgggacc gcacggcgac ctcggtgccc tggaccaagg atctgctcgg cggcaacggc
     5821 cggcgctccg accagcaggt gacgaccggt ccgttcgcct attcgacggg caactgggcc
     5881 atcaaggtgg gggtcaccga cggccgctac ctcacccgcg acctcggccg cgccgcctcg
     5941 cccatccaac tgcccacgaa ggacgacgtg agctgggcgc tgaacgaccc ggtctacgac
     6001 gtacagccct gggactccac cgtcacccag ggcttccgga acaagctgga gggctggggc
     6061 accggcagcg gcagcgcctc ctggcacaac cacaaccggg tgcaccgctg ggtcggcggg
     6121 gcgatgctcg gcgccgcgtc ggtcaacgac ccggtgttct ggctccacca cgcctatctg
     6181 gacatgcagt gggagcgctg gcagggggcg cacagcagcc accgctatct gccggccgct
     6241 ccgcccggca ccggtgacgc gcagcacggc cgggtcgtcg cccggcacga caagctgccg
     6301 ccgtggagcg acaccccgga tcagctggag gacatgagcg gggtctaccg gtacgagtga
     6361 gttcggaccg gtgagctcgg gccggcgagt tcgtgatggt gagctcgcgc cggtgggttt
     6421 ggatcggtga gggacgcgaa gagccccggc gctcggaggt gccggggctc ttcgcggtgc
     6481 gcgacggggc ctcagccgcc gtagctgctg ttgccgtagc cgttgctggg ctgcgcgaga
     6541 gtgccgccct ggttgacgca ggtgttgccg aaggccgggt tcagcagacc gatgacgtcg
     6601 accgagtcgc cgcacacgtt caccgggatg ttgaccggaa cctggatcac gttgccggac
     6661 agcacgccgg gcgaaccgac ggccgcgccc tcggcgcccg cgtcggccag agccagcccg
     6721 gccccaccga tcaccacggc accggtgccg agggccacgg cggctgcctt cgcgatgcga
     6781 gacatcacgt tcctcctgtc gatcgggata cgcgacggct ggtcctgccg tcgcactccc
     6841 cgttcaacgc ggccgtccgg caggggtcac ggtgatcagc gggggatcac cctttcaaca
     6901 gacaggtatc cgttctcgga cgtttcacgg caattgtcgt accggagatt tcgccagata
     6961 ggcctggatg tcctccaccg cctgagtgaa gtacgtccgg tagttggccg cggagacata
     7021 gccgaggtgc ggggtggcga gcaggcgggg ggcggtgcgc atcgggtggt cggcgggcag
     7081 gggctcgatg tcgaagacat cgatgccggc acccgcgatc cggccctcgt gcagcgcggc
     7141 gagcagggcg tcctggtcca ccaccgaggc acgggaggtg ttgatcaggt aggcggtcgg
     7201 cttcaggagg gcgagttcgg cggcgccgac cagaccccgg gtgcgatcgc cgccgggcac
     7261 atgcacggag acgaagtcgt tctcggccag caactcctcc ttggaggcag ccagttcgac
     7321 cccggcggcc gcggcacgct cctcggtcag tcgcgggctc cacgcggcga cacgcatccc
     7381 gaaggcgagc ccgacccgcg cgaccttgcc gccgatccgg ccgagcccga ggactccgag
     7441 gcgggcgccg tgcagatcgg caccgacggt ggactgccag ggcccgccgg tgcgcagcgc
     7501 ggtgttctcc tggacgatcc cccgggcgag cccgagcagc agcgcccagg tcagctcgac
     7561 ggggggagtc ccggagctct gcgtcccgca cacggtgacg ccgtacttct cggccgcggc
     7621 gtagtcgatc acggtgttgc gcatcccggt cgccacgatc agccgcagcc ggggcagccg
     7681 ggcgagcaac gagcccggga agccgacgcg ttcgcgcagg gtgacgacga tgtcgtactc
     7741 ggcgagcgcc gtggcgagcg cgtcctcgtc ggccagatgt gtacgcagcg atacgacctc
     7801 caccgcgtcc ccgagcaccg accagtcggc cgactcgacg gccacgccct ggaagtcgtc
     7861 cagcaccgca cagcgaagtc gcacgccgtt ctcccctcac gatccgagca ctccgaagtg
     7921 ttttttgagc gcctcgaagt atgtcggacg gcggggcgcg ctcacgcggg ggtgggtgcg
     7981 accggtgcgg acgtcgccga cttcccctgg gcgaactcca gattggcggc gatgcgcgcc
     8041 cgctccccct ccgggacctt cccgccgtcc agcagccgtg tgcagtactc ccgggacttc
     8101 tcgtagtcac cgatccaata ggaggccacg gcgagttcgt ccagcgcgcg ccattcgtgc
     8161 caggacatct cgacgaagag aatgtcttcg ggccggggga tcccggccgc ccgcgcggcg
     8221 aacaggtgcg ccagcggcca gcgcccttcc aggcggcaga gccgggcgag atccccgatg
     8281 gcctcgatgc gtgaaggacg gctttcgtac gcgcgaagat atcggtcgat caattctccc
     8341 gctggcctct tgagttggac ggcgagccgt gccgcataaa gtttggcgca gtacgtctct
     8401 tccacccacc cggccatctc cgcccttctg tcataggcgg ccagggcctt ctccggctcc
     8461 tcggcgtccc gccagctctg ggccaggtag aaggcgtaac gggcattgtc cggttcctcg
     8521 accaatgcct tggcgagaat ctccgcgtcc cgcagatact tctcccgctt cccctcgtcc
     8581 cgcagccgcg ccccgccccc gacggtgagg atgtgggccc cctccagcgt cccggtgctg
     8641 tggggcgcgt cgcacgtgat gtactcgtgg agcacccctt cgtaccgcca tggcagccgt
     8701 gtggcgacca acgccatccg ccagtgcacc acgggtccgt cgtgcagggc gatgttgtag
     8761 gcgtccagcg tcagctcggg catccggaac ccgggccgga tgcgcatctc gtcgtcggcg
     8821 tcgatgaaca gcagatagtc cgcgctgccc cgcgccaact cgatcgcctc actgcgactg
     8881 ccgtcgaacc ccttccattc ccgttcgtgg agctctccgg gaaagtcctt gaaacaatcc
     8941 cggatcacct cctgggtccc gtccgtcgac cccgtgtcca cgatcaccca ggtatcgacc
     9001 aggggtcgca ccgactcaag gcatttccga atggtcggag cctcgttctt cacgatcata
     9061 ttcaggcaga cgctcgccat gaattcctcg cactgtcgct cggagccgcg ttccgttcgg
     9121 ggactctaat ggaaggggag cgggaatccg gcgtatttgc ggggctgtgg ctgtccggtg
     9181 ccgatggcac actcggtacg gtggcgggac gaagaggggg agaagccgag gtggccggga
     9241 ccgggaacaa cgagcgacgc cgcactcgac gagccagcgc tgtccgccgt gcgcaactcg
     9301 ccctgctcgt tctggtcgtc ctcctggtcg gcgctcgtgt gtgggagcgg gagcagggtg
     9361 gtgactccga ctcgaccatg ttcggcccga tggccgcgtc ggcactttcg atcggggtcc
     9421 tggagcgctg tcgggggaga ctgaccaagg actctcgatg gccgcgcggt gatcgctgga
     9481 gctgggggaa ggctccgcga ccgggcgacc ggccttcgcg gtggttggct cactcgtaca
     9541 tggtcgccgc ccgcagagcc tgtgcgaaga aagcccagtc accgccgggc ggcagatccc
     9601 ggccggtgtt gccgtaccag ccgtccgcgt cgtcgatcca ggccgccaag gcctccagga
     9661 agctcgaaag atccgcgttc tcccacgaca cccccttctc ggcgtggtcg agacgcaggg
     9721 aacggacgaa ggccgccagg tcttccctgc tgccgacgcg atcgggagaa gtggtcacgc
     9781 caggggacct tacccggcgg gtccgaccga gaaccgcgcg cgtcgcgtga cctgggacgg
     9841 ctccactccg ggcgacttgg gcgcgcttct aagcgggtcg gcccgtgctc tgccgctgag
     9901 ccgcgtcggc gagccgcttc acataccgat gcgcgggcac cgtgacctgt ccctggtcgc
     9961 gcggtgcgaa ctgctcgaac ggcccttggt ccgtccaccc gttgcgctcg tagaaccgtc
    10021 gcgcccgagc gttgcccggt acgacggcca gccacgcctg acggtgacca ccggccgcga
    10081 caaggcgctc cgcctcctcc agcagagcca cggccacccc ggcgcctctg tgccgctcgg
    10141 cgacgtaaac ctgctcgacc tcgtcgtcga ccaccatgac gaaccccgcg acctcaccac
    10201 cgacgaccgc gaccgtcgtg tcggccagcc ggcgcggggc ccgttccgcg aaggactccc
    10261 gcgtccgcac cgcgaccagc gcgtcaggaa cgttccccag gtgcccgtcg cgccaaccgc
    10321 ggtacca
//
