LOCUS       NZ_CP094483            25272 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces murinus strain JS029 chromosome.
ACCESSION   NZ_CP094483
VERSION     NZ_CP094483.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces murinus
  ORGANISM  Streptomyces murinus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Draft genome sequence of Streptomyces sp. JS029
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAR-2022) Agricultural Life Science, Sunchon National
            University, Jungangro 255, Suncheon, Jeonnam 57922, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-MAR-2021
            Assembly Method                   :: Unicycler v. 0.3.1
            Assembly Name                     :: JS029
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 164.82x
            Sequencing Technology             :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028753175.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 03:30:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,582
            CDSs (total)                      :: 7,481
            Genes (coding)                    :: 7,273
            CDSs (with protein)               :: 7,273
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 215
            CDSs (without protein)            :: 208
            Pseudo Genes (ambiguous residues) :: 0 of 215
            Pseudo Genes (frameshifted)       :: 110 of 215
            Pseudo Genes (incomplete)         :: 125 of 215
            Pseudo Genes (internal stop)      :: 20 of 215
            Pseudo Genes (multiple problems)  :: 41 of 215
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:08:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3801072
            Orig. end                         :: 3826344
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP094483.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from National Institute of
            Biological Resources.
FEATURES             Location/Qualifiers
     region          1..25272
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="21"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25272
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25272
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15272](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15272
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(965..1177)
                     /locus_tag="ME763_RS16625"
                     /old_locus_tag="ME763_16610"
     CDS             complement(965..1177)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005483585.1"
                     /locus_tag="ME763_RS16625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_16610"
                     /product="excisionase family DNA-binding protein"
                     /protein_id="WP_085565767.1"
                     /transl_table=11
                     /translation="MADRLLTVGEAAEQLGTGERFVRRLIAERRIRYVKLGRPVRIPKS
                     AVTEYIEARTVEPVRHTRLRYGRAA"
     gene            complement(1334..1591)
                     /locus_tag="ME763_RS16630"
                     /old_locus_tag="ME763_16615"
     CDS             complement(1334..1591)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009321502.1"
                     /locus_tag="ME763_RS16630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_16615"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_085565766.1"
                     /transl_table=11
                     /translation="MAARSLEIGPAGIRAARNIEILRTERGLPQRELAARVTALGRPMS
                     NTMLSRIERAQRRCDIDDLVAIAQALHVPVPALLRGPATA"
     gene            2093..3001
                     /locus_tag="ME763_RS16635"
                     /old_locus_tag="ME763_16620"
     CDS             2093..3001
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004928353.1"
                     /locus_tag="ME763_RS16635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_16620"
                     /product="hypothetical protein"
                     /protein_id="WP_085565765.1"
                     /transl_table=11
                     /translation="MARIRTIKPEAFVSESLAAVSLTAERTFFGLLTQADDQGRHRDHA
                     AIIAGQLWVLRPEHTAADVEKDLAQLADAGLICRYTGPDDKRYLHVVTWHQHQKINRPS
                     KSRLSACPHHDTVGGAARAGLTEAAPLPHGTLREGSRQRQETTVNTGDVRESAVQEDFT
                     GPSVKTHDRLTEQSVSPHGPDLGPRIVDLGSTPSGGASAPAPDTVSAKHLIAEYAAACT
                     HRPPKDVLGHLGQEVRKLLDEGIDPAHIRAGLELHRAKGLHPRILPSLVHEAMNAAPAR
                     QVVHRAWTNPADVAAAYGDQL"
     gene            2998..3693
                     /locus_tag="ME763_RS16640"
                     /old_locus_tag="ME763_16625"
     CDS             2998..3693
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1151: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983962.1"
                     /locus_tag="ME763_RS16640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_16625"
                     /product="ATP-binding protein"
                     /protein_id="WP_085568657.1"
                     /transl_table=11
                     /translation="MTATLTREPQQVGPIAARLNGILARRDIDPAAAAAGEAPAEPVTA
                     LELADARIPARYRRALAGHPQITAWADEIARAGRPGPGGPGIAEGPSLLIAGPTGTGKT
                     HQAYGAIRTLLARGVRLRWEATTTADLHARLRPRAGHDTERDLQTLARSPLLLLDDLGA
                     VRTSEWTEELAYRLINHRYEHMLPTLITTNLPTAELRTTLGDRVASRLAEMTERVILDG
                     PDRRRHQPT"
     misc_feature    complement(4060..4074)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.35"
                     /tool="antismash"
     gene            4350..4847
                     /gene="mobC"
                     /locus_tag="ME763_RS16645"
                     /old_locus_tag="ME763_16630"
     CDS             4350..4847
                     /codon_start=1
                     /gene="mobC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983963.1"
                     /locus_tag="ME763_RS16645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_16630"
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="WP_085565764.1"
                     /transl_table=11
                     /translation="MAEPDRHQEVPARQAATEGGSQPEEKPSPRTPRATKKTSRKRSPK
                     PTADKRDYVCSVRLNDDEKTQLTAAARATRTSLPAFLARSGLAAAQDLDNTAAAIAGHR
                     ELVTELFAARRHLGQVGNNLNQIARALNTGAHPAELDAVVTAVQRAVSRVQAATDRLLE
                     QH"
     gene            4946..>5262
                     /locus_tag="ME763_RS16650"
                     /old_locus_tag="ME763_16635"
                     /pseudo=""
     CDS             4946..>5262
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070645.1"
                     /locus_tag="ME763_RS16650"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="ME763_16635"
                     /product="mobilization protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGLLSYLHGPANTKNTTTRTWSPPGTTTHPTPAATPPPPSNSSSS
                     SWISPSTTSTMSSGRKSTCGTCPSATPPRTGSCPTRSGARWPAGWSPPASTTPTRTRAA
                     D"
     gene            complement(5334..5861)
                     /locus_tag="ME763_RS16655"
                     /old_locus_tag="ME763_16640"
     CDS             complement(5334..5861)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380192.1"
                     /locus_tag="ME763_RS16655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_16640"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_085565763.1"
                     /transl_table=11
                     /translation="MTRVIDLRHYGQGSLPEGFKQMLIKVHADAYADAMDDEFNQRFPW
                     FVDHWSEMDGFTCVVAFDGDEPTGFAYGAPLQPGREWWRSTGFEPNNGYTATYAVSEVM
                     VRPRWRKQGISERLHEALLKERSEDLAVLLVDVTHPKVQALYETWGYEKAGEQQPFADS
                     PVYAVMVKRLRP"
     gene            complement(5858..7111)
                     /locus_tag="ME763_RS16660"
                     /old_locus_tag="ME763_16645"
     CDS             complement(5858..7111)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140649.1"
                     /locus_tag="ME763_RS16660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_16645"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_085565762.1"
                     /transl_table=11
                     /translation="MAANLALRRRLDQLGLTQDELAARLNAALQEITGRPGEISSRTVR
                     NLLNGSSRRPIGRTCAALERVFGCPVADLGFRAPSSMQHPPEGPVRRRDFIVSATGTAA
                     AAVPVVTQRRAVGMADVARAAARMNRLVEADDRQGGHTSLASAALEARAKVLELQQRNA
                     SERVRRALYALAAEFTTIAAWSCIDVRDLGTAQTYLHESSTFAGLAQDPVTGMRVWVNM
                     AILAYQRKNWPEQLAAAQAANASPAARRDPFFGSMGRVRLALAHSSLGDLRAARRALGT
                     AQETFQKATEDERPRWTAFYGPAELNHLAAIILNRNGEPAEAEAMAHRALAKIPAEFQR
                     NRALATCQLALAQLRQGEPEQATATAATVFTIMDGAPLPGRMRTLIGDFHRDLFRLAPS
                     TTYARDWADRMRDEWSRA"
     misc_feature    complement(6890..6892)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(7161..7175)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.32"
                     /tool="antismash"
     gene            7348..7773
                     /locus_tag="ME763_RS16665"
                     /old_locus_tag="ME763_16650"
     CDS             7348..7773
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380190.1"
                     /locus_tag="ME763_RS16665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_16650"
                     /product="ATP-binding protein"
                     /protein_id="WP_274506880.1"
                     /transl_table=11
                     /translation="MTVAKPNAIGAPGYTMELPCVRESMSRARALVSNVLATWGMDDDA
                     ADCGRIIVTELLANAVEHTQTLVSKVIIERPSNGAVRIGVSDRSHGVPHLRAAALNAES
                     GRGLRLVAGMSSRWGYDTHPWGKVTWAVIEASAGREQ"
     gene            7770..8189
                     /locus_tag="ME763_RS16670"
                     /old_locus_tag="ME763_16655"
     CDS             7770..8189
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380189.1"
                     /locus_tag="ME763_RS16670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_16655"
                     /product="DUF6415 family natural product biosynthesis
                     protein"
                     /protein_id="WP_085565761.1"
                     /transl_table=11
                     /translation="MSIAVAPKRPTAEWAPPLDADGLRLVLERFRAWKPLDVEDIFDDL
                     DAAIGSHSPSVATTAALVDRLRSHLKQLSDITVADDSFPPTAEMARLVARARALRNECT
                     PTAHQQAVGLARRLAFVTADLVEELIEARYIKGTE"
     misc_feature    7836..7838
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            8407..9639
                     /gene="fxlM"
                     /locus_tag="ME763_RS16675"
                     /old_locus_tag="ME763_16660"
     CDS             8407..9639
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490583.1"
                     /locus_tag="ME763_RS16675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_16660"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_085565760.1"
                     /sec_met_domain="PCMT (E-value: 3.1e-36, bitscore: 123.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPNTTVEPAEATRLRNKVVDELRADGNISSPEIEAVMRKVPRHAF
                     IPDTPLDKAYDTYAAVITKTDEHGVQLSSVSAPQIQAMMLEQAQVKPGMRVLEIGSGGL
                     NAAYLAELVGPKGEVVTVDIDPGVTDRASRLLEEHGYDKVLVVTADAAEPLPIGEVDVV
                     MVTAGAWDISPAWISQLKQGGRLVVPLRMRGLTRSVAFTQVVGEHGPYLESESTRICGF
                     VPMQGSTAHREELLLVNGTPEIGLKFDDGLPADPHRLDNAVTFPRHELWTGVVIGLQEL
                     IDTLQMAMAISLPGFCTMAVDEDLDTGLVAPVNKRFSLAAVEDDTFAYLVTRRTEDNKH
                     IEYGVHALGPNAKQFADKVADVLRDWEANRRGGPSPTIRVYPAGTPDDQIQADQVIDKV
                     HSRISLSWPPA"
     gene            9692..9883
                     /locus_tag="ME763_RS16680"
                     /old_locus_tag="ME763_16665"
     CDS             9692..9883
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380187.1"
                     /locus_tag="ME763_RS16680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_16665"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_085565759.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 5.1e-15, bitscore:
                     53.9, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSATLAPPAPLAGLDDDFAPLDVKVVVAEHAYGHLMCSTGDGCG
                     STCATGASACGSFTEDPA"
     misc_feature    9959..9973
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 23.67"
                     /tool="antismash"
     gene            10001..13063
                     /locus_tag="ME763_RS16685"
                     /old_locus_tag="ME763_16670"
     CDS             10001..13063
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380186.1"
                     /locus_tag="ME763_RS16685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_16670"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_085565758.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.3e-198,
                     bitscore: 659.1, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 3.1e-18,
                     bitscore: 65.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.9e-11, bitscore:
                     42.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASRAVADYQWQGTAMLRATTSPGPADIPRTLDLDNVAVTRAWLN
                     RIWQRKDFRSALELAAPVLSDAIEAVVQSRQTEPRHVRRTAVSTVSYLLRWQHRPTPLG
                     LFAGTAPVTVGPRATARWRDKHRVLIRPDAEWVTDMVLRLQRAHALLKRLPLVANNAAH
                     TRGDRLVAPGPPSDGHAVLLAPVEISVRNTRPVAAAMDAARSPIPYGDLHDHLRDSFPQ
                     ATPEQIDTLLTSLVEQQFLITSLWAPMTTVDAFQHLCHELERHSAESVPEVRDLVHELY
                     ALRDDVSAHQPTLSDTSVGAIAARMHALTPVTPTPLLIDTALDCETQLPQAVIVEAQAA
                     VSALYRTTPQPYGYQHWRDYHRRFRARYGVGALVPVMDLVSDSGLGLPAGYIGSERGAA
                     LKVRTDRDELLLALMQQVLLDGRDELRLTDDMVSALEKAAGTDERLFVPRVEAAFEVHS
                     PSTRALSKGTFDLLLTAAPRPGSSMAGRFAHVLPPEHQDALAATYRGAPDRLTAQLVFP
                     PRRHRNENVTRTPLLLPHIIELSGHQENDKTAIRLTDIAVTADPRSFHLVQLSTGLRID
                     VRVLHALEGGTQTPPLARFLAEVANGRYAAYKPFDFGVASRLPFLPRVRYRRTILTSAR
                     WLLTAEDLPGRKAPRQEWEDAFTVWRDRLRVPMRVAVIEYDQRLPLDLSHPAHLRILRA
                     HLDNTRRVELREVTDADAHGWIGRAHEIWLSLGRSEPDTHVPRPRHARTPGSVRHLPGA
                     GGVLHAQLHAHPRRYDEILSHHLPHLIAAFDKEPPTWWFTRHREMARPDADQHLDLTLH
                     LPPEAHAAGAQHVRAWADSLHRLGLASGLVLAPYQPQTGRFGSESAMDAAHQVFAADSA
                     AALAQIQLTERNHAFAAQALAAASALHLVTRLAPDTATAEEWLVHNLPQGTGRLNRALR
                     SEVLELASPNSASALAALPGGPQVTEAWRARAATVDTYRDALAGERDPLDVARSLLHQH
                     HVRALGVDPRAEETTIRLVRTAALQHRMAAR"
     misc_feature    10448..10450
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        10469..10744
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_ME763_RS16685_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="1.20E-20"
                     /identifier="RREFam001.1"
                     /label="ME763_RS16685"
                     /locus_tag="ME763_RS16685"
                     /protein_end="248"
                     /protein_start="156"
                     /score="65.0"
                     /tool="antismash"
                     /translation="VANNAAHTRGDRLVAPGPPSDGHAVLLAPVEISVRNTRPVAAAMD
                     AARSPIPYGDLHDHLRDSFPQATPEQIDTLLTSLVEQQFLITSLWAP"
     gene            13060..14292
                     /locus_tag="ME763_RS16690"
                     /old_locus_tag="ME763_16675"
     CDS             13060..14292
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490581.1"
                     /locus_tag="ME763_RS16690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_16675"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_085565757.1"
                     /sec_met_domain="LANC_like (E-value: 4.8e-39, bitscore:
                     132.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTLAATAAAILEQYTAHLAEPPPPPPEEPWAVQSLADGAAGISL
                     LHIETASRYGGSWRSAHRWITSAASGPISAADQTGLFLGAPAVGFLLSAVPPAYRHLYA
                     SARTILHQHITDLANRRVDAALARIDRGDLPTFSEYDLFYGLTGIGAYLLRTEPEGPAL
                     ERILQYLVALTRPLAPTGRGLPGWWVRHDPARGESPHFSGGHGNFGAAHGITGPLLLLA
                     QALRRGVTVQGHQDAMFTICAHLDAWCQHGDSGPWWPEHISRLDLDHRRPHHDAPARPS
                     WCYGTTGIARAGQLAGLALRSPTLQKFYEDALYRALTDPAQLALVTDTGLCHGWAGIYQ
                     TAHRAAADALDPRLRTLPERLGGALAASGQPGSSSTPGLINGTAGTALAFTTFASHQAP
                     STGWDACLLIN"
     gene            14316..15272
                     /locus_tag="ME763_RS16695"
                     /old_locus_tag="ME763_16680"
     CDS             14316..15272
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006379081.1"
                     /locus_tag="ME763_RS16695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_16680"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_274506255.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 4.4e-30, bitscore:
                     104.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNAVSAVLAGRSLADAAHQYRLDPVVLSDAVAVYDQAGREALGR
                     HAATTDWWQTYLHFTDWPNADTTFATQVLPILREAETTGALDGWWYTRKHPCWRLRLRV
                     QPVGGAKLAIGDGFDRLVTDGHLQRWWPGIYEPETPAFGGKTSMTAAHALFVTDSRQIQ
                     QLRQRDDLFVGPRELSVLLCTIMMRAARLEWYEQGDVWDRVITTEHRSAISDVPPERLN
                     ARAREIRPLLLAGGDALLRSGGPLEPVAEWAAAFHSAGRALAHGVQDGSLDRGLRQVLS
                     YHVIFHWNRLGLSMRGQSMLGWAARAAILHGDEHKES"
     misc_feature    15030..15032
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(15468..15479)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 20.58"
                     /tool="antismash"
     misc_feature    15556..15571
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.59"
                     /tool="antismash"
     gene            15680..16891
                     /locus_tag="ME763_RS16700"
                     /old_locus_tag="ME763_16685"
     CDS             15680..16891
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020387.4"
                     /locus_tag="ME763_RS16700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_16685"
                     /product="HEPN-associated N-terminal domain-containing
                     protein"
                     /protein_id="WP_172427584.1"
                     /transl_table=11
                     /translation="MGADEIEQAQADQGWDYGYGFVCAGCVDDENLARKIADDADEHET
                     CDYCDRAPAAPLDTLLEAFFDGLHTEFALAGDELAYFESELVPVKHWEGDELVNEYVDV
                     LRGEDLQETVREAARHDDVWVERHFIEPRHDEALLDGWRRFSHEVMYRTRHVFWLAPSH
                     PDEAHLGGGEIPAAAILDALGGLIPQAGLIHEIPAGHRLWRARTHDAEQPWSARELGTA
                     SPAQARHPNRMSPAGIPLFYGADTPTAAIQEVACHASDSAKLVTYAAFETTRSCRVIDF
                     TRLKPIPTIFDTDGAPLRRALMFLHEFVNRLSADADGHEHLTYVPTQIVTEYLLRVFDR
                     ERPVKGLVYNSAASRDGRCTVLDIPQTHCLDADSAEPDAQTALRLVPGTLHANQPLPRD
                     LLRP"
     misc_feature    complement(17242..17256)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 21.84"
                     /tool="antismash"
     gene            17301..17897
                     /locus_tag="ME763_RS16705"
                     /old_locus_tag="ME763_16690"
     CDS             17301..17897
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005492.1"
                     /locus_tag="ME763_RS16705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_16690"
                     /product="hypothetical protein"
                     /protein_id="WP_085565753.1"
                     /transl_table=11
                     /translation="MEQTWGALAVAVVGVIGTLGAALLTQSRADRLKRHELEATARQQR
                     EDRAHAEQVRQHENRLVARRELIDLRRACYISLNTTARQYQTAQINLMHALRARDDTET
                     QACVEQLEARRLVFRDSYAEAQMIAAGAVLTDARAASRQLNKAYGLLKRMVAGGHPDTI
                     ELDALETETEKSSALLSHLRAAMHHDLGVDEGSEE"
     gene            complement(18187..18990)
                     /locus_tag="ME763_RS16710"
                     /old_locus_tag="ME763_16695"
     CDS             complement(18187..18990)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS16710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ME763_16695"
                     /product="hypothetical protein"
                     /protein_id="WP_274506256.1"
                     /transl_table=11
                     /translation="MGWRVSVVLAEVAVSRLHWTWGMRAMAHYRWMGKAGNGAALNLLD
                     WTLVLVIMSGVTLWPVYWATRWSSTARFQLVLAVIDAVLADGKACTAPRGWRTSRALRQ
                     VDESCRRVEKCLFKVHSIAGSVPRRSSRLGLIKRHAALVAGAQRAALHKLDIDPEPAFA
                     ELARLQLVIGENHLRGRQAALLPAELLLDVRPVSRLRNTWRESAHMAMAILVAMAAAAG
                     AAHLLPSIGVPEDLRPWLTLGAAVLAATLVAGWGRVTRILELLPA"
     misc_feature    complement(18868..18870)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(19467..20234)
                     /locus_tag="ME763_RS16715"
                     /old_locus_tag="ME763_16700"
     CDS             complement(19467..20234)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268373.1"
                     /locus_tag="ME763_RS16715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_16700"
                     /product="transposase"
                     /protein_id="WP_085565751.1"
                     /transl_table=11
                     /translation="MGGVISADDPKWIEPFSGLTGVQFARLVALVRRRGGDVQRGRPWR
                     LSLEDRVLLVATYWRTNLTLRQVAPLFGVSKSAADRILDHHAPLLAISPARRPRKDTVY
                     IVDGTLVPTRDRSIAASSKNYRYSTNLQVVIDANSRLVVAIGLPLPGSRNDCRAFTESG
                     VDRACRGTPTIADGGYQGTGLLTPHRKRRGQTHLNPRQEAENAVHRRARARVEHALSRL
                     KNWKILRDCRLKGNGVHQAMLGIARLHNLALTG"
     gene            complement(20265..20591)
                     /locus_tag="ME763_RS16720"
                     /old_locus_tag="ME763_16705"
     CDS             complement(20265..20591)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS16720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ME763_16705"
                     /product="hypothetical protein"
                     /protein_id="WP_274506257.1"
                     /transl_table=11
                     /translation="MSKKLRQPSYYSSVSSERSLIRGLSRMTAGAVGRHDDRSSAGGAH
                     LSGIDARALGEGMVLADALDGGKQFAHDAFGLVALGRKIEKYGPVLRGCQRRVGCIRWL
                     EVVP"
     misc_feature    complement(22266..22279)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.06"
                     /tool="antismash"
     misc_feature    complement(23453..23468)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.94"
                     /tool="antismash"
     misc_feature    complement(23980..23993)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     misc_feature    complement(25156..25168)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.42"
                     /tool="antismash"
ORIGIN
        1 gcgagggtgt tgccggtgtg ccgcaggtcg tagaagcgga agttgtccgg catgccgacc
       61 tgcttcctgg ccttgcgcca cttgcggccg aaggtcgagc ggcggaacgg agcgcccttc
      121 tcaccgacga agaggagacc gtccggctcc ttctccgcga accaccgaat gtgtcgacgc
      181 agctccggca gcaggaggtc gggcaggtac acggtgcgtt tgcccgcgcg ggtcttgggg
      241 gcgccggtga cccgcttgcc gtttgtcagc tccggtgagg cgtgcgtgat ccgcagggag
      301 cactcgtcga gatcgacact gtggcggcgc agctcggcca gttcctcggg gcggagggcg
      361 gcgaaggcgc cgagcaggac catgagccgc cagcgcgggc ccatggcgtc ggcgaggtcg
      421 aagacctgct ccacggtcgc ggtggggcgc tcgtcggcct cctccttgcc ggcgcccttg
      481 atgcggcacg ggttggtcgg gaggagatcg tcgtcgaccg cggtctgcag gatcgccttc
      541 agcagccggt acgacttggc gaccgtggtg gcgcccgtcg ccttccgccg ttcggcacgc
      601 caggcgcgaa cggcgggcgg agtgatctcg tccaggtccc tgccgccgaa cgtcggcagg
      661 atgtgcaggc ggagcaggcc gctgtagcgg tcgaccgtgg tcggcgccag accgcgttcc
      721 tccagccacc gcagcgcgta cttctcgaag ttgaccgcgc cggcgtccgg gttccgccac
      781 tggttgcggt cgatgtccgc gcggaccagg ttgagccagt cctgcgcgtc ggtcttggtg
      841 tcgaacgtct ggggggcctt gtgacgggtc ccgtccgggc cgacgtaacg ggcctgccac
      901 cggcccgagg cgagccggcg tacggtgccg aactcgcgtc ggcgctgggg tctgcgtcct
      961 gccatcaggc tgccctcccg taccggaggc gggtgtggcg gaccggctcg acggtgcgtg
     1021 cctcgatgta ctcggtgacg gcgctcttcg ggatgcggac cgggcggccg agcttgacgt
     1081 agcggatgcg gcgttcggcg atgaggcggc gcacgaaccg ttcgcccgtg ccgagttgtt
     1141 cggcggcttc gcccaccgtc agcagacggt cagccatggg tgatcacctc cttcggagcg
     1201 cgctgaagac gggatcggac agggggtatt gcgggtgggc gcaagtgcgg tggctcctca
     1261 ctcggggcgg aggcggggcg gcggttctgg aggtggaggc gccgtggggg ttctcggagt
     1321 ggcgaagtcg gattcaggcg gtcgccgggc cgcggaggag ggccgggacc ggcacgtgca
     1381 gcgcctgtgc gatggcgacc aggtcgtcga tgtcgcagcg gcgttgggcg cgttcgatgc
     1441 gggacagcat cgtgttggac atcggccggc cgagagcggt gacacgagcg gcaagctccc
     1501 gctgcgggag gccgcgctcg gtgcggagaa tctcgatgtt tcgggcggcc cttattccgg
     1561 ctgggccgat ttccaatgaa cgtgctgcca tggctccgtt gtagcgtgca ctcgccggtt
     1621 tggttaaccg gcgatcgtcg gctatattgc gccccgcgca cacggcacgc gggggtacgc
     1681 ccctctcgtc agcccgtgcg tcgagcagcg ccgacagggc gtctgacgtg gggtgttgtg
     1741 ttgcagcttc gctgcccgcc aacgtcaacg gtttgccgat gtgatccttc tggctcgggt
     1801 ttccgggcaa ctatttggtc agcgggcgat cgtgccctac cgttttcccg ccgccctctc
     1861 cgacctgttt tccgaccgcc tttctgccgt cagagatctg gccgtttggg gctggacttg
     1921 tccgcactgg gtgtggctat gttgacgaca gccccggaaa agccgcgagc ggctcaacga
     1981 gccgagcggc agccggtcgg caactccccc acacctgacg cccccaccgc ccccgtcgac
     2041 ggtgagccat gggtgcccgc cccctggcca ccgagtgagg accgccccgc tcttggcacg
     2101 aatccgcacc atcaagcccg aagccttcgt ctccgagtcc ctggccgccg tctccctgac
     2161 cgccgagcgc accttcttcg gcctgctcac ccaggccgac gaccagggcc gccaccgcga
     2221 ccacgccgcg atcatcgccg gacagctgtg ggtcctgcgc cccgaacaca ccgccgccga
     2281 cgtcgagaag gacctcgccc agctcgccga cgccggcctc atctgccgct acaccggccc
     2341 ggacgacaag cggtacctgc acgtcgtcac ctggcaccag caccagaaga tcaaccggcc
     2401 cagcaagagc cgactctccg cgtgccccca ccatgacacc gtcggcggcg ccgcacgagc
     2461 cggcctcacc gaggccgcac cgctgcctca cggaaccctc cgtgagggct cccgccaacg
     2521 gcaggagacg acggtgaata ccggagacgt acgcgaaagc gcagttcagg aggatttcac
     2581 ggggccctcc gtgaagacgc acgaccggct cacggagcag tcagtgagtc ctcatggtcc
     2641 ggatctagga cctaggatcg tggatctagg aagtacccct tcgggaggcg caagcgcccc
     2701 cgcgcccgac accgtctcgg ccaagcacct catcgccgag tacgccgccg cttgcaccca
     2761 ccgcccgccc aaggacgtcc tgggccatct cggccaggag gtgcgcaagc tgctcgacga
     2821 gggcatcgac cccgcacaca tccgggccgg tctcgaacta caccgcgcca agggtctgca
     2881 cccccgcatc ctgccgagcc tcgtgcacga ggccatgaac gccgcccccg ccaggcaggt
     2941 tgtccacagg gcgtggacga accccgccga tgtcgccgcc gcctacggag accagctctg
     3001 accgccaccc tcacccgcga accccagcag gtcggcccca tcgccgcccg cctcaacggc
     3061 atcctcgcca ggcgtgacat cgaccccgcc gcagcggctg ccggggaagc cccggccgag
     3121 ccggtcaccg ccctggaact ggccgacgcc cgcatccccg cccgctaccg ccgcgccctg
     3181 gccggccacc cgcaaatcac cgcctgggcc gacgagatcg cccgcgccgg ccgccccggc
     3241 cccggcggac cgggcatcgc ggaaggcccg tcactgctga tcgccggccc caccggcacc
     3301 ggcaagaccc accaggcgta cggcgccatc cgcaccctcc tcgcccgcgg ggtccgcctg
     3361 cgctgggaag ccaccaccac cgccgacctc cacgcccgcc tgcgcccccg cgccggccac
     3421 gacaccgaac gcgacctgca gaccctggca cgcagcccgc tgctgctcct ggacgacctc
     3481 ggcgcggtca ggaccagcga gtggaccgag gagctggcct accggctcat caaccatcgg
     3541 tacgagcaca tgctccccac cctcatcacc accaacctcc ccaccgccga actccgcacc
     3601 accctcggcg accgcgtcgc ctcccgcctc gccgagatga ccgaacgcgt catcctcgac
     3661 ggccccgacc gacgacgcca ccagcccacc tgaaccggca gcggcccgcc gaccacgggc
     3721 ggcggacctc cgaggagctt tcacccgggg agccggagtg gtgccgggac cgaacgcgag
     3781 ggcagaggac cgactccggg gaccaggacc gggaccgagg gcggggaccg aggaggcggg
     3841 gaccgagcgc ggggaccggt ccccaacgtg cggggaccat ccggggacca ccgcagcgac
     3901 aacccgttgg ggaccgaggc ccgactcgga gaccgaactt ggggaccggg gaccaccccc
     3961 agggaaccgg ggaccggtcc ccgggaccga gaccccggtc cccacatttt cgggaccggc
     4021 atccgccgat gacccatacc ccagtccccg cacgtcagcg cccagaagaa gtggggaccg
     4081 gtccccactc tcggctcggg tccgagaaca gcccacacac acgcccacct ggccgaccgt
     4141 ccgcgccctc cctccccacg agccacacaa cgccacacga caggccatgc ctcagctggc
     4201 cgagagagac ttccgtgcac caggcaaacc acgaatcacc ccccaacccc cgccgggacg
     4261 ccaccacccg ggccccaggc ggagcaagtt atcggccaag acactcttcc ccgccggcga
     4321 aggcgccctg gccggagccc gccccggggg tggcggaacc ggaccggcac caggaggtgc
     4381 cggcccgcca ggcagcgacc gagggcggat cgcagccgga ggagaagccg tcaccgcgca
     4441 cgccccgcgc cacgaagaag acctcgcgca agcgctcgcc gaaaccgacc gcggacaagc
     4501 gcgactacgt atgcagcgtc cgcttgaacg acgacgagaa gacccagctc accgccgccg
     4561 ctcgcgcaac ccgtacgagc ctgcccgcct tcctcgcccg cagcggcctc gccgccgccc
     4621 aggacctcga caacaccgcc gccgccatcg ccggccaccg tgagctggtc accgaactgt
     4681 tcgccgcgcg ccggcacctc gggcaggtcg gcaacaacct caaccagatc gcccgcgccc
     4741 tcaacaccgg tgctcaccct gccgaactcg acgcggtcgt cacggcggtc cagcgcgccg
     4801 tgagccgcgt acaggcagcc acagaccgac tgctggaaca gcactgaccc ggcacccgga
     4861 cgacgccccg tccccaccag ccccagcacc catctcggac accagatgat gatcccccgg
     4921 atacagaaag cgcgggcagc gcaccatcgg cctcctgtcc tacctgcacg gcccggcaaa
     4981 cacgaagaac acgacgaccc gcacctggtc gcctcctggg accacaacgc acccgacccc
     5041 ggccgcgacc cctccgccac cctcaaacag ctccagcagc tcctggatca gcccgtcgac
     5101 aacctcgacc atgtcgagcg gccgaaaaag cacgtgtggc acctgcccat ccgcaacgcc
     5161 gccgaggacc ggctcctgcc cgacgaggag tggggcgaga tggcccgccg gatggtcgcc
     5221 gccggcatcg acgaccccga ccaggacgcg ggctgccgat ggcccgaccg tcagcgatca
     5281 cgagttgggc cggtatgtgg cgtcgcccgc aactgactcg ggagcggagc cgttcaggga
     5341 cgcagcctct tcaccatgac cgcgtacacc ggggagtcgg cgaaaggctg ctgctcgcct
     5401 gccttctcgt agccccacgt ctcgtacagg gcctgcactt tggggtgcgt cacgtcgacc
     5461 agaagcaccg cgagatcttc gctgcgttcc ttcaacaggg cttcgtggag ccgctccgag
     5521 atcccctgct ttcgccatcg cgggcgcacc atgacctcgg agacggcgta ggtcgcggtg
     5581 tacccgttgt tcggctcgaa cccggtggaa cgccaccact cccggccggg ctggagcggg
     5641 gcaccgtacg cgaagccggt cggctcgtcg ccgtcgaagg cgacgacgca ggtgaagcca
     5701 tccatctctg accagtgatc gacgaaccat gggaaccgct ggttgaactc gtcgtccatc
     5761 gcgtcggcgt aggcgtcggc gtgcaccttg atcagcatct gcttgaagcc ttcggggagg
     5821 cttccctgtc cgtaatgccg caggtcgatc accctggtca cgctcgactc cattcatctc
     5881 gcattcggtc tgcccagtcg cgggcgtacg tcgttgacgg cgccagccgg aacaggtctc
     5941 ggtggaagtc tccgatcagg gtgcgcatac gcccaggcag tggtgcgcca tccatgatcg
     6001 tgaagacggt ggccgcggtc gcggtggcct gctcgggctc tccctggcgg agttgtgcca
     6061 gcgcgagctg gcaggtggcc agcgcgcggt tgcgctggaa ctccgccggg atcttggcca
     6121 gggctcggtg cgccattgcc tcggcttcgg cgggctcccc gttgcggttg aggatgatcg
     6181 ccgcgaggtg gttgagttcg gccggcccgt agaacgcggt ccatcgggga cgctcgtcct
     6241 cagtcgcctt ctggaaggtc tcctgcgctg tgcccagtgc cctccgagcg gctcgcaggt
     6301 ccccgagcga cgaatgggca agcgcgaggc ggacgcggcc catggagccg aagaacgggt
     6361 ccctacgggc ggccggagag gcgttggcag cctgtgctgc cgcgagctgt tccggccagt
     6421 tcttccgctg gtaggcgaga atggccatgt tgacccacac gcgcatgccc gtgaccgggt
     6481 cttgggcgag gccggcgaac gtggacgact cgtgcaggta cgtctgggcc gtacccaggt
     6541 cgcggacgtc aatgcacgac caggcagcga tggtggtgaa ctcggccgcg agtgcgtaca
     6601 gggcccggcg cacacgttcg ctggcgttgc gctgctgaag ctccagcacc ttggcgcgag
     6661 cttcgagagc tgcgctcgcc agggaggtgt gcccgccctg gcggtcgtcc gcctccacaa
     6721 gccggttcat tctggccgcg gcgcgggcta cgtccgccat gcctactgcc cggcgctgcg
     6781 tgacgaccgg aacggctgcg gctgccgttc cggtggcgga aacgatgaag tcgcgtcgcc
     6841 gcacgggtcc ctccggagga tgttgcatgg aactgggggc gcggaaccct aagtccgcca
     6901 cggggcagcc gaacacacgc tcaagtgctg cgcaagtgcg gccgattggg cgtctgcttg
     6961 atccattgag caggttgcgg accgttcggg aggagatctc gccgggtcgg ccggtgatct
     7021 cctgtagcgc agcgttcaac cgggccgcca actcatcttg ggtgaggccg agttggtcca
     7081 atcggcgccg aagggcgagg ttggctgcca tgtaccgaac gtagtaccgc agtcactctg
     7141 atgcccagac ctcaggtaat tggaacgcaa agtcttccgg ttggcgggca tgcacagaac
     7201 cgggtctttt cctgttgcgc tccgcttgtc actcgttgac tggtcattgg ccaccgagtc
     7261 gggttcggca cggtggcacg gaggaaagcc cggccctgcc ccccgtcagg accgggtatc
     7321 ccacgccgga gggaagacct cgtgaccatg accgtcgcta aaccgaatgc gatcggcgcc
     7381 ccgggctaca ccatggagct gccctgcgtc cgcgagtcca tgagccgtgc ccgcgctctc
     7441 gtctccaacg tgctggcgac ctggggcatg gacgacgacg cggccgactg cggaagaatc
     7501 atcgtcaccg aactgctggc caacgccgtc gagcacaccc agaccctcgt gtcgaaggtc
     7561 atcatcgagc gtccgagcaa cggtgccgtt cgcatcggag tttccgaccg ttcgcacggc
     7621 gtgccccacc tgcgggcggc ggccctgaac gccgagagcg gccggggtct gagattggtc
     7681 gccgggatga gttcgcggtg gggctacgac acgcacccat ggggcaaggt cacctgggct
     7741 gtgatcgagg cttcggccgg acgagagcag tgagcatcgc agtggctccc aaacgcccaa
     7801 ccgcggagtg ggctcctccg ctcgacgcgg acggcttacg gctcgtgttg gagcgatttc
     7861 gggcctggaa gccgctcgac gtcgaggaca tctttgacga tctcgatgcg gcaatcggca
     7921 gccattcgcc gtctgttgca acgaccgccg ccctggtcga ccgcctccgc agtcacctga
     7981 agcagctcag cgacatcaca gtggctgacg acagttttcc acccaccgct gagatggccc
     8041 gactcgtcgc gcgagcgcgc gctctacgga atgagtgcac gccgaccgcc catcagcagg
     8101 ctgtcggact cgcccggcgt ctcgctttcg tgaccgccga cctggtcgaa gaattgatcg
     8161 aggcccgcta catcaagggg accgagtgac gtgcgccccc acccacttgc gtgccgctca
     8221 gcgggctgag cagtacgcac cggcctgccg agcgatcctc cacaggcgtg cgcctcccca
     8281 cttgccgtcc atcacaccgc cccgttggtc agccgacgag aacggagaac gttcgcccat
     8341 agcctcccgg cccaaccagc acacgatgtc gacctctccc tgaacacgca cgaccgaagg
     8401 aacttcatgc cgaacacgac cgtcgagccc gccgaggcga cccgcctgcg gaacaaggtg
     8461 gtggacgagc ttcgcgcgga cggcaacatc tcctccccgg agatcgaagc cgtgatgcgc
     8521 aaggtgcccc gccacgcgtt catccccgac accccgctcg acaaggcata cgacacgtac
     8581 gccgctgtga ttaccaagac cgacgagcac ggtgtgcagc tcagctccgt ctctgccccg
     8641 cagatccagg ccatgatgct ggagcaggcg caggtgaagc ctgggatgcg agtgctggag
     8701 atcggctcgg gcggcctgaa cgcggcctac ctcgccgagc tcgtcggacc caagggcgaa
     8761 gtcgtcaccg tggacatcga ccccggcgtc acggaccgcg cgtcccggct cttggaggag
     8821 cacggctacg acaaggtcct cgtcgtcacc gccgacgccg ccgaacccct ccccatcggc
     8881 gaagtcgacg tcgtcatggt gaccgccggg gcctgggaca tttccccggc gtggatctcg
     8941 cagctcaagc agggtggccg gctcgtggtg ccgctgcgga tgcgcgggct gacccgatca
     9001 gtcgccttca cccaggtcgt gggcgagcac ggcccctacc tggagagcga gtcgacgagg
     9061 atctgcggct tcgtcccgat gcagggctcc accgcccacc gcgaagaact tctcctcgtc
     9121 aacggcactc cagagatcgg gctgaagttc gatgacgggc tgccggccga cccgcaccgg
     9181 ctggacaacg cggtcacgtt cccgcgccac gagctgtgga ctggcgtcgt catcggcctc
     9241 caggaactca tcgacaccct ccagatggcg atggcgatca gcctgcccgg cttctgcacg
     9301 atggcggtcg atgaggacct ggacacgggt ctggtcgccc ccgtgaacaa gcggttctcc
     9361 ctcgccgccg tcgaggacga caccttcgcc tatctcgtca cccgccgcac cgaagacaac
     9421 aagcacatcg agtacggcgt acacgccctc ggcccgaacg cgaagcagtt cgccgacaag
     9481 gtcgccgacg tcctgcgcga ctgggaggca aaccggcgcg gcggccccag cccgaccatc
     9541 cgggtctatc cggccggcac ccccgatgac cagatccagg ccgaccaggt catcgacaag
     9601 gtccacagcc ggatctcgct ctcctggccc ccggcgtagc gccgcgagcc aggtagtccc
     9661 gcaccatccg aacaagaaga agggcatcac catgacgagc gccaccctgg ccccgcccgc
     9721 cccgctggcg ggcctggacg acgacttcgc gccgctggac gtgaaggtcg tcgtcgccga
     9781 gcacgcgtac ggccatctca tgtgttccac gggcgacggc tgcggcagca cctgcgcgac
     9841 cggcgcctcc gcctgcggct ccttcacgga ggatcctgcc tgatcctcgg ttcctttccg
     9901 aaaaacccgg cctgatccag gccgttccct gctggttggc cgggcgaagt gctccgcccg
     9961 gccaaccggc cctcacccgc cccgccagac ggagggcacc atggcttccc gagcagtcgc
    10021 cgactaccag tggcagggca ctgccatgct gcgcgccacc accagccccg ggccggcaga
    10081 catcccgcgc accctcgacc tggacaacgt ggccgtcacc cgcgcatggc tgaaccgcat
    10141 ctggcagcgc aaggacttcc gcagcgcgct ggagctcgcc gcccctgtcc tgtccgacgc
    10201 catcgaggca gtcgtccaga gccggcagac cgagccccgt cacgtccgcc gcaccgccgt
    10261 atcgacggtc tcctacctcc tgcggtggca gcaccggccg accccgctgg gcctgttcgc
    10321 cggcaccgcc cctgtgacgg tcgggccccg ggcgaccgcg cgatggcgcg acaagcaccg
    10381 cgtgttgatc cggccggacg ccgagtgggt caccgacatg gtcctccggc tccagcgcgc
    10441 acacgcctta ctgaagcggc tgccgctcgt cgccaacaac gccgcccaca cgcggggcga
    10501 tcggctcgtg gcgccgggcc caccctccga cggccacgcc gtcctcctgg ccccggtcga
    10561 gatatccgtc cgcaacaccc ggccggtagc cgcagccatg gacgccgccc gctcccccat
    10621 cccctacggc gacctgcacg accacctgcg cgacagcttc ccgcaggcca caccggagca
    10681 gatcgacacg cttctcacca gcctggtcga gcagcagttc ctcatcacca gcctgtgggc
    10741 gcccatgacc acggtggacg ccttccagca cctgtgccac gagctggaac ggcacagcgc
    10801 ggagagcgtc cccgaggtgc gggacctggt ccacgagctg tacgcgctgc gcgacgacgt
    10861 gtccgcccac cagccaacgc tctccgacac cagcgtgggc gccatcgccg cgcgaatgca
    10921 cgccctcacc cccgtcaccc cgacaccgct gctcattgac accgccctcg actgcgagac
    10981 ccagctcccg caagccgtga tcgtggaagc gcaggcagcc gtgtcggcgc tgtaccggac
    11041 caccccgcag ccctacggct accagcactg gcgcgactac catcgccggt tcagggcccg
    11101 ctacggcgtc ggtgccctgg taccggtgat ggacctggtc tccgacagcg gcctcgggct
    11161 gcccgccggc tacatcggct ccgaacgcgg cgccgccttg aaggtacgca ccgaccgcga
    11221 cgaactgctg ctcgcgctga tgcagcaagt cctcctcgac ggccgtgacg aactgcggct
    11281 gacggacgac atggtcagcg ccttggaaaa ggccgccgga acggacgagc ggctgttcgt
    11341 gccccgcgtg gaggccgcct tcgaagtcca ctcacccagc acccgagcgc tgtccaaggg
    11401 caccttcgac ctcctgctca ccgcggcacc ccgccccggc agcagcatgg cgggccggtt
    11461 cgcccacgtc ttgccgcccg agcaccaaga cgccctcgcc gccacctacc gcggtgcacc
    11521 ggaccgcctc acggcgcagc tcgtgttccc accgcgtcgg caccgcaacg agaacgtcac
    11581 ccgcacaccg ctactgctgc cgcacatcat cgagctgtcc ggccaccagg agaacgacaa
    11641 gacggccatc cggctcaccg acatcgccgt caccgccgac ccacgcagct tccacctcgt
    11701 gcagctctcc accggcctgc gcatcgacgt gcgagtcctg cacgccctgg aaggcgggac
    11761 acagaccccg ccactggccc ggttcctcgc cgaggtggcc aacgggcggt acgccgccta
    11821 caagccgttc gacttcggcg tcgcctcccg acttccgttt ctcccccggg tgcgctaccg
    11881 ccgcaccatc ctcacgtcgg cccgatggct gctgacggcc gaagacctgc ctggccggaa
    11941 agccccgagg caggaatggg aggacgcctt caccgtctgg cgggaccggc tgcgggtccc
    12001 gatgcgggtc gccgtcatcg agtacgacca gcgcctcccc ctcgacctgt cccacccggc
    12061 ccacctccgg atcctgcgcg cccacctcga caacacccgg cgcgtggagc tgcgcgaagt
    12121 cacggacgca gacgcccacg gctggatcgg gcgagcacac gaaatctggc tctccctggg
    12181 ccggtccgag ccggacaccc atgtgccccg gccgcgccac gccaggacgc ccggttccgt
    12241 gcggcacctc ccgggcgccg gcggtgtcct ccatgcgcaa ctccacgccc atccacgtcg
    12301 ctacgacgaa atcctgagcc accacctccc ccacctgatc gccgcgttcg acaaggagcc
    12361 gcccacctgg tggttcaccc ggcacaggga gatggcacgg ccggacgccg accagcacct
    12421 cgacctcaca ctgcacctgc caccagaggc acacgcggcc ggcgcacagc acgtccgtgc
    12481 ctgggcggac agcctgcaca ggctgggtct ggcgtccggg ctcgtcctgg ctccgtacca
    12541 gccacagacg gggcgcttcg gcagcgagtc ggccatggac gccgcgcacc aagtgttcgc
    12601 cgccgactcc gccgccgccc tcgcgcagat ccagctcacc gagcgcaacc atgccttcgc
    12661 cgcacaggcc ctcgccgccg ccagcgccct gcaccttgtc acccgcctgg cgccggacac
    12721 cgcgacggcc gaggagtggc tggtgcacaa cctcccccag ggcaccggcc ggttgaaccg
    12781 ggccctgcgc agcgaggtgc tcgaacttgc ctcgccgaac agcgcctccg cgctcgcggc
    12841 actccccggc ggtccacagg tcaccgaagc atggcgagcc cgcgccgcta ccgtggacac
    12901 ctaccgggac gccctggccg gtgagcgcga tccgctcgac gtcgcccggt cgctgttgca
    12961 ccagcaccac gtccgggctc tgggcgtcga tccgcgcgct gaggagacca cgatccggct
    13021 cgtgcgaacg gcggcccttc agcaccggat ggccgcccga tgaccacgct ggccgccacc
    13081 gccgcggcga tcctggagca gtacaccgcc catctggcgg aaccgcctcc cccgccccca
    13141 gaggagcctt gggcggtcca gtcgctcgcc gacggcgcag ccggaatcag cttgctgcac
    13201 atcgaaacag ccagccgata cggcggctcc tggcgctccg cccaccggtg gatcacgagc
    13261 gcggcctccg gccccatcag cgcggccgac cagacgggtc tgttcctcgg cgccccggcc
    13321 gtcggcttcc tcctcagcgc cgtccctccg gcctaccggc atctgtacgc ctcggcgcga
    13381 acgatcctgc atcagcacat caccgacctc gccaaccgtc gtgtggacgc cgcgctcgcc
    13441 cgcattgaca ggggagacct gcctaccttc tcggagtacg acctcttcta cggcctcacg
    13501 gggatcggcg cctaccttct gcgcaccgag cccgagggcc cagccctgga gaggatcttg
    13561 cagtacctcg tcgccctgac tcggccgctc gcccccaccg gacgagggct ccctggctgg
    13621 tgggtccgcc acgacccggc gcgcggcgag tccccccact tctctggcgg gcacggcaac
    13681 ttcggcgccg cgcacggcat cactggcccg ctcctcctcc tggcccaggc cctgcgccgc
    13741 ggcgtcaccg tccagggcca ccaggacgcc atgttcacca tctgcgccca cctcgacgcc
    13801 tggtgccaac acggtgattc cggcccgtgg tggccggagc acatctcgcg tctcgatctt
    13861 gaccacagac gaccccacca cgacgcacca gctcgaccga gttggtgcta cggcacgacg
    13921 ggcatcgccc gagccggcca acttgccggg ctcgccctgc gctcgcccac actccagaag
    13981 ttctacgagg atgccttgta ccgggccttg accgatcccg cgcaactcgc cttggtgacc
    14041 gacaccggcc tctgtcacgg atgggcgggc atctatcaga ccgctcaccg cgcagccgca
    14101 gacgcgctcg acccccgact gcgcaccctc ccggaacgcc ttggtggcgc cctcgccgca
    14161 tccggtcagc ccggctcctc atcaactccc ggcctgatca acggcactgc cggcaccgcg
    14221 ctcgccttca ccaccttcgc ctcgcaccag gcgccgagca ctggatggga cgcatgtctc
    14281 ttgatcaact gactcaggca accgagccga tcccgatgca gaacgccgtc tcggccgtcc
    14341 tcgccggccg gtcactcgcc gacgcggcgc accagtaccg gttggacccc gtggtcctct
    14401 ccgacgcggt cgcggtctac gaccaggccg gccgggaagc gctgggccgc cacgcggcca
    14461 ctaccgactg gtggcagacg tacctccact tcaccgactg gccgaacgcc gacaccacct
    14521 ttgccacgca ggtcctgccc atcctgcgcg aagcggagac caccggcgcg ctcgatggct
    14581 ggtggtacac cagaaagcac ccctgctggc ggctgcgcct ccgggtccag cccgtgggag
    14641 gcgccaagct ggccatcggg gacggcttcg accgcctcgt caccgacgga caccttcagc
    14701 gctggtggcc cggcatctac gaaccggaga caccggcatt cggcgggaag accagcatga
    14761 cggcagcgca cgccctgttc gtcaccgaca gccgacagat ccagcagttg cgccaacgcg
    14821 acgatctctt cgtcgggccc agggagctct ccgtcctgct gtgcacgatc atgatgcgcg
    14881 ccgcccggtt ggagtggtac gagcagggcg atgtctggga ccgcgtcatc acaacagaac
    14941 atcgctcggc catcagcgac gttccgccgg aacggctcaa cgcccgcgcc cgcgagatcc
    15001 gccctctcct tctcgccggc ggtgacgcct tactgcgctc cggaggcccg ctggaacccg
    15061 tcgccgaatg ggccgccgca ttccacagcg ccggccgagc actcgcccac ggcgtccagg
    15121 acgggtcgct ggatcgcgga ctgcgacagg tgctcagcta ccacgtgatc ttccactgga
    15181 accggctcgg actgtccatg cgcgggcaga gcatgctggg ttgggcagcc agggcagcga
    15241 ttctgcacgg cgacgagcac aaggaaagct gaggcgcgcg atgacgcgca ccgtcgtcgg
    15301 taacagctta tgagagccga aacgatcatc taggggtggt ccacgggcgg ggaagctcga
    15361 cgacgactcc gggtaagcgt ctcaccatcg ccgccaaggc cgaactgccc tgcacctgct
    15421 gctgagcagc acgcctgtgc acctcgaacg ggccgaggca caggtcggcg ttcacgtccg
    15481 ccggatcgcc gagaccctga cgaaggagga tctgtgtgcc aatgaccacc gggttcgtcc
    15541 tcgggttaca cccggattgg tcatgaccac aacctggggt ccacgatcaa ggggaagctt
    15601 caaccgacgc gtgctccgcg cctgggaacg gttcccatca tgcgctcgtc tgcgccttca
    15661 tacatctacc gtgtctccca tgggcgcgga tgagatagag caagcacagg ccgaccaggg
    15721 ctgggactat ggctacggct tcgtctgcgc cgggtgcgtc gatgacgaga acctcgcccg
    15781 gaagatcgcg gatgacgcag acgaacacga aacctgcgac tactgcgacc gcgccccggc
    15841 agcccccctc gacaccctcc tggaagcctt cttcgacggg ctgcataccg agttcgccct
    15901 agcgggcgac gagctcgcct acttcgaaag cgaactggtc cccgtcaagc actgggaagg
    15961 cgacgaactc gtcaatgaat acgtggatgt cctgcggggc gaggacctac aagagaccgt
    16021 ccgcgaggcc gcccggcacg acgacgtctg ggtggaacgc cacttcatcg aaccccgcca
    16081 tgacgaagca ctgctcgacg ggtggaggcg cttcagccac gaggtgatgt accgcaccag
    16141 acacgtgttc tggctggccc cgtcccaccc ggacgaggca cacctcggtg gaggcgagat
    16201 cccggccgca gcgatcctcg atgcccttgg tggcctcatt ccccaagcag gcctcatcca
    16261 tgagattccc gccgggcacc gcctgtggcg cgcccggacc catgacgccg agcagccctg
    16321 gtccgcacgt gagctgggaa ccgcgtcgcc cgctcaggcc cgccacccca accggatgag
    16381 tccagcaggc atccccctct tttacggagc cgacaccccg accgctgcca tccaggaagt
    16441 cgcctgccac gccagcgaca gcgccaagct ggtcacctac gccgccttcg aaaccacccg
    16501 ctcctgccgg gtgatcgact tcacccgcct aaaacccata ccgaccatct tcgacaccga
    16561 cggcgcaccc ctacgacggg cgctgatgtt cctccacgaa ttcgttaacc gcctcagcgc
    16621 cgatgctgac ggccacgaac acctcaccta tgtgccgacg cagatcgtca ccgagtatct
    16681 cctacgggtt ttcgaccgag aacgacccgt aaaggggctc gtctacaact ccgccgccag
    16741 ccgtgacgga cggtgcaccg ttctcgacat cccccaaact cactgcctcg acgcggacag
    16801 cgcggagccc gacgcacaaa ccgccctgcg cttggtccca ggcacgctgc acgcaaacca
    16861 gccgctgccc cgcgacctcc ttcgaccgta gagaccgacc catgccgcca gcgaccactg
    16921 ggccggtctt caggtcatgc cgccggtcgc ggggcttgac cagcacgccc ccactctcgg
    16981 cttcgctcaa gcgggaggta cccccagccg cgttgtcgtc ggccgccaac atcccccagc
    17041 cttcggccgg ggggtacccc aacgcgttga ctccctcctc cgccttgcag atacacgcgc
    17101 caagccccgc tcaccccagc cgacaagccg cccggcgcgg tagccggctc gatccgaaag
    17161 acacagcatg aagcctctgc cagcaaggag cttctaccgg agaatcgggc gttgggtcac
    17221 ggcacaaggc agcaccctat gatcgacacc attgatgcag gcgggacagc aacacacctg
    17281 cccgatgcga ggtgagagct gtggaacaga cctggggtgc gctggctgta gccgtggtcg
    17341 gtgtcatagg caccctgggg gcagcgctgc tgacacagag cagagccgat cgtctcaagc
    17401 gccacgagct cgaagcgacc gctcgtcagc aacgcgaaga ccgcgcccac gccgagcagg
    17461 tccggcaaca tgaaaatcgc cttgtggcac gacgcgaact gatcgacctg cgccgcgcct
    17521 gctacatctc cctcaacacc acggcacggc agtaccagac cgcgcagatc aacctcatgc
    17581 acgccctgcg cgcccgggat gacacagaaa cccaggcgtg cgtcgagcaa cttgaggcac
    17641 ggcgcctggt ctttcgcgac agctacgccg aagcacagat gatcgcggcc ggcgccgtac
    17701 tgacagacgc ccgagcggca agccgccagc tcaacaaagc ctacggccta ttgaagagga
    17761 tggtggcagg tggccatcct gacaccatcg aacttgatgc ccttgagacc gagacggaaa
    17821 agtcgtcggc gctgctgtcc cacctgaggg ccgccatgca ccacgatctc ggtgtggacg
    17881 agggctccga agaataggga ctcggccagc ggcaggccca ccccgcgcac caaggacgcg
    17941 tgcaaggaag acatcggcgg ccgtcgaccg actgacaggg gccctgccga cggggcgtcc
    18001 acatcagacg cgcccgagca gccaccgggc cgagagccac tcgcgcttgt gctcgctggc
    18061 ggcgctccgc tccaactcag cctagcccgc ccataccgca tgatcggccg gttcggggga
    18121 atctgaagtg accgcagcat gcatatccga cacggccacg ctgagccaca tcgggcgaga
    18181 tctgcgtcag gcaggaagca gttcgaggat gcgagtgacc cgtccccagc cggccaccag
    18241 cgtcgcggcg agaaccgccg ctcccagcgt caaccacgga cgcaagtcct cgggcacccc
    18301 gatcgacggc agcaggtgcg cggcacccgc agccgccgcc atggccacga ggatcgccat
    18361 ggccatgtga gccgactcgc gccaggtgtt ccgcagacgc gacacgggtc gaacgtcaag
    18421 gagcagctcg gcgggtagga gcgctgcctg tcgaccgcgc aaatggttct caccgataac
    18481 gagctgcagc cgcgccagct cggcgaatgc cggctccggg tcaatatcca gcttgtgcag
    18541 cgcagcacgt tgagccccgg cgaccagtgc agcatgccgc ttgatcagcc cgagcctgga
    18601 ggagcgccgc ggaacggaac ccgcgatgct gtgaaccttg aacaggcact tctccacgcg
    18661 ccgacagctc tcgtccacct gacgcagcgc ccgggacgtt cgccagccac gaggcgccgt
    18721 gcacgccttg ccgtcggcca agactgcgtc gatcactgcc aggaccagct gaaaccgagc
    18781 ggtggagctc caccgtgtcg cccagtacac gggccacaga gtcactccgg acatgatcac
    18841 aaggacgagc gtccagtcga ggaggtttaa ggccgcaccg ttcccagcct tgcccatcca
    18901 gcgatagtgc gccatcgctc gcatgcccca ggtccagtgc aagcgtgaca cggcgacctc
    18961 cgccagtacg accgatacac gccagcccac ccacgcgaca atccagcccc cgacaagggc
    19021 gagcgcacag accgcccagt tcggacgcca tgacccgaga acgccacgga ccgtcgaagc
    19081 ttcctccagg gggataccca acttctctag ggctgcgtca agttcccttc tcctcaaccc
    19141 tgcccagccg cgctgctgac cggatctcct gagccagagc ctatggcgag cccacagacg
    19201 caccgcccgc cgctccagat ctaaatcgaa agaagccatc cgtcccccac cccagttgtg
    19261 cctcacatgg cgcggagacg cagtatgcac catcccgatt gagaccaagg caggcatcga
    19321 cgccgcagac gggggcggcc tcagcgtgat cacccgcccc acagggcaag cccgttcaga
    19381 tgtcacccga tcgtgcggca gaccccgacg cctcatcgca ccaagcgaaa cggcgaggct
    19441 agaggttgtc ccgtatgggg tgcgggttat ccagtgaggg ccaggttgtg gagtcgggcg
    19501 atgccgagca tggcctggtg aacgccgttg cccttgagtc ggcagtcgcg caggatcttc
    19561 cagttcttca gccgtgacag ggcgtgttcc acgcgtgctc gcgcccggcg gtgcacggcg
    19621 ttctccgctt cctggcgggg gttgaggtgg gtctggcctc gtcgtttgcg gtgcggggtg
    19681 agcaggccgg ttccctggta gccgccgtcg gcgatggtag gtgtgccgcg gcaggcccgg
    19741 tcgacgccgg actccgtgaa tgcccggcag tcgttgcggc tgccgggcaa cggcaggccg
    19801 atcgccacca ccaggcgact gttggcgtcg atgacgacct gaaggttggt tgagtaccgg
    19861 tagttcttgc tggatgcggc gatgctgcgg tcgcgggtgg gcaccagggt gccgtcgaca
    19921 atgtagacgg tgtccttgcg tggccgacgg gccggcgaga tggccagcag gggcgcgtgg
    19981 tgatcgagga tgcggtcggc ggcggacttc gagactccga acaacggcgc cacctgccgc
    20041 aacgtgaggt tcgtgcgcca gtacgtcgcc accagcaaca cccggtcctc cagcgacagc
    20101 cgccacggcc ggccccgctg cacgtcaccg cctcgacgcc gcaccagcgc aaccagcctg
    20161 gcgaactgca ccccggtcaa ccccgagaac ggctcgatcc acttcggatc atctgctgag
    20221 atcaccccac ccatacccag ccaacgcacc aaccgcccca ccggttacgg gacaacctct
    20281 agccagcgaa tgcatccaac acgacgctgg caccctcgta gaaccggccc atatttttcg
    20341 atcttcctgc cgagcgcgac gaggccgaac gcatcgtggg cgaactgttt gccgccatcg
    20401 agcgcatcgg ccaggaccat cccttcgcca agggcacggg catcgatgcc cgacagatgg
    20461 gcgccacccg cgctgctacg gtcgtcgtgc ctgccgacgg ccccagccgt catcctgctc
    20521 aaccctcgga tcagcgaccg ctccgaggag acggacgagt aatacgaggg ctgcctcagc
    20581 ttctttgaca tccgcggcct catcccccgc ccactgaaga tcacggtgga agccgtcacc
    20641 ctggctggtg agaccacgac cacgcactac gagcgcggcc tcgcccgcct catccaccac
    20701 gaagaaaatg ggagagcatc gctcagccta aaaataaggc aggcatcatg cgatgctctt
    20761 gccgcagcag tgcttgaact tgcgcccagc gcgcatcata cacggacaag gaccattcct
    20821 ccgtgggcgc actactgtca acggcaccgt ggcaccaacg gcctgaccag aatccatcgc
    20881 ctgcagcagg tacttcatgt catcagccgc cattccctgg agatttcggc cgaccacgat
    20941 aatcagagtt cctgcgcggg cagcccgata ccagtgaggg aagaagttaa gcggtatgcc
    21001 aggcatcaaa atggccgagg gtccggagac ccagagcctg ttatcttcca gacgagcttg
    21061 tatattgccc acctggactt gagggatagt tctgaggtcc aacacatcac catcttcaag
    21121 gccagcgagc atgctctgaa ggttggtgaa cccggcggca aggtggctgt ccaggaccag
    21181 gtcttggatt ggcccaccgt ctaccgatcc ccagccgccg tagcagtcga cgatgacgcc
    21241 tgccctgtcg ccgccgaata ggatgcattc cacctcaggg atgatcttgg gtgcttttgg
    21301 gggcttccct ttcagttcga tcacctggga ggccacacag tgcgggtgcg caagacgcac
    21361 cagcacgtgc tctacttccc ggtggcgtag cagcagcaat tcagccacac cggtctcgtc
    21421 gatcaacaga ttgcagccct cgcagatctg tcgggagttg gcaagccgat caagtagccg
    21481 cgtgatgtct tgctctgcca gttcctgcag gaccgacgat gcgatattga tgcgtctccg
    21541 gtccggagta atctcctcac ccaacaggtc gtggctacca ggggacgcca gcttccgacc
    21601 agtggactgc aagcgtgtac gaatagattc caagatccga ccgtctagca gcttctgcgt
    21661 gccaagaagt gcgtcaatcg tgggctcagg ggcgtttggc tcatcgccga cgtgaagtcg
    21721 ggccagctcg agcagcgcct cccctgcctc tgaccagccg ccgattcgct ggtggacacc
    21781 gaatgcttcg cgcgcgtgtt ggcgggcggc gtcggcctgg ccgagagccg cgtgggtacg
    21841 agccaggttc atcaagcaag gggccagaag agattcattg ttgatctcct caaatacgac
    21901 ccgggcacgg ttaaagcgtt cgagagccaa gccatgccgc cccgaactgg cataatgagt
    21961 gccaacatta ctatgtatgg ccgcttccag ggagcgcatt cccagccgct gggtcatcga
    22021 cgaaaggtgg tcgagatcag caagggctcg ttccggatcc cccatgttga ggctacacat
    22081 ggcagcctgc gtcctcgcga cgagtagaac gtggatattc ttttgctctt cagcgagttc
    22141 ctcgaccctg cggtactcat cgagagcgtc tgcccatttt tcactacggg cgtgtatgtt
    22201 cgctagcgcc attctggcgt gcagggctat tgaagtggcg ccagcctgct cacaggcatc
    22261 aagcgctcta gtaatcatag tttgggcctc cgcatggagg ccgcggcgtg aatataggat
    22321 ggcgagcgcc cggtttgcct gagccttggt gagcggagtg gcgtcgtcag aggtgttgga
    22381 ggcaacctcc tccagcatcc gagcgccgct ttgccaccgt tctgagtcta ggagggcttc
    22441 ccccaaggcg gttctggcct gcgccctagc ctgcttgtgc tcggtgttct ctagaaggcg
    22501 gaccgcctcg gtcagaagag aaacagcatg gctaattcgg ccggtgtgcc aggcgagttc
    22561 ggcttgcttc tgtagtgcct gcgccatgac gactgggtta gcggtgtgac gcgccatgtc
    22621 ctgggcttgc tcgaatagag catccgcttc gtccagacgc ccgacgcgtc cgcgataggc
    22681 cgcaaggtaa gacagcgctt gggacgcatg gtcgtagtcg ccgatacctg tcgccaaacg
    22741 cacacattcg cctaggtgtg cggcagccgt atcgatctct gctcgctcgg cagcccgact
    22801 tcccaggcga tacaacgctc gcacttggcc ttggatatct ccgctgtccc ggtagatagc
    22861 caatgccgcc tctagcgggt ccgctggagc agaactcggc cgatcctgcg ggggcgtctc
    22921 ggcgagcgcc atcagggccg cggcctccca cattcgactt cctaccgtac gggccctttc
    22981 gatgtcctga gtggcttgct gtgccgcctc agccatgcgg ccgccggaac gtagcagtgt
    23041 tccgagggtg cctcggttcc acatgtctgg agcggtgccc gacttcaaga ggctgcggct
    23101 gttgcgtagg tagtgctcgg cccggcggac ctggccgacg gcgaggtatg cctggccaag
    23161 gttgcccaga gcctggccca acacctgctg gtagccagtg ccgcgccaga aggggagccc
    23221 gttgcgtaga tagggaattg cgtctcgggg gcgtccgaga ttgatgagaa gtgatcccat
    23281 tgccaactct gcaaggtgca tcagatgggg gtcttcggca tcatgggcgg tctgggctgc
    23341 ctggtggaaa aggtcggccg cgcgctggct gtcgccgacg tgactagcga ccgtggcgag
    23401 gttgtggagg gcagtggccg tccagttgat attgccagaa ctggctcccg cttcgaacac
    23461 acattggtag gcacgttcga ggtcgcccca atgaccgcca tgccacaggg acgcagtgtg
    23521 gttcgccacg agagtgacga gcggttccca gatctggtag tcccgtgcaa ggtcggttag
    23581 agcgaccgca ccggggcggt ctgcgttgag ctgctgcacg gcttcgaggt tgctcggtgc
    23641 cgggatggtg gcttcccggt cgataaagcc gattgattcg gtggctgact ctgcgcgcgc
    23701 agcggccatt agacaagcgt gccgaaccac agtttcgcgg tccgctgtag gcgttgagcc
    23761 cgacttgagg cgggcgaaac gatgcagaat ctcgtggaag acatagcggc cttcgtcgac
    23821 ctgctcaatg aggctcaact cgaagagctc atcaaggagt tctgctacca cgttcgcttg
    23881 gatatcggca agctggtcgg acgaggtgcg ggccgcggcg gcgacatcga cggtgatgga
    23941 catgtgcggc aggacgccga gcaccgtgaa cagatgcgct tgctctgcat ccagatcagc
    24001 gaagcttcgt tcgagcaccg gttgaatcgc gacccgaccg gcccgcaggg ccttcagccc
    24061 gtgttcaggg ctggcgatat ccctgatgta ccgctctgca tcgaccttcg gacgccttgc
    24121 caagtgggcg gccgcaatgt gcaaggcgag gggatgccca ccacaggctt gggcgagatc
    24181 cgccgcctgt gtgtccgtga gccgtgtagg cccggcgacg gccctcacga gcgcctcgcc
    24241 gtgctcggcg ggcaaggggc caacctcgac acagtggacc aacccggcaa ggccgctcag
    24301 ctttgctcgg ctcgtaccca gcaatgcaaa ggggccgtcc atctgcagca cctccaacag
    24361 cgcctcctcc gagacgatgt cgtcaatcag cagcaggacc ctgcggccgg ccaacgtgga
    24421 gcggaggagt gcgcggcgct gggtctgccc ctcaggcagg cgatcaccaa cgggcctcag
    24481 agcctgaagg agcgcggaaa tcaggtcaac ttcggctcct tcgccagcag caagagccaa
    24541 atcaaggtgg tactgcccat cagggaagtc cccctccacc atgtgcgcca gcttcaaagc
    24601 caaagaactc ttccccatgc ccggtgcacc ggtgaccagc accgagcgcc tgctgcccgc
    24661 attgggtgct tggagggctg gcagagcctc ctgcaaggct tcgtcacgcc cgatgagcgg
    24721 ccgcaactct cgaggtagcc cgtacccagc agacggtcca gatggcgtac gggatgcgtc
    24781 gagttcctga agcatctcgt acagccgagc caggacatcg ccgggcagca cggcgtcagc
    24841 attggcgtga cgcacgtcct tgttgttgtc gaggagtcgg cagattgtct cgtagtgcca
    24901 gatctcccag cccttgagtg ggaggttcag ctgacgtaca cgttcgcgaa ctgcgtcatg
    24961 aacacggtca atgccaccac tgcccggaac ggcagacagg acgacgttcg tcgtgatcaa
    25021 gaggtagtcc ggaaggcgac ccttgcgaac ccgattggag gtcggatcgc cccatgcgtc
    25081 cagctctgcc ctgacatgct tgatcagcca atccgcgtcc ttcccggtac cttccgggcg
    25141 gctacggaac ttggcctgca aaacgccata tccggtccat ggcgcatcgg ggttcgggaa
    25201 ccgggtcagt ccctcgaagg tggcctctcg cccaccgtca gggccagcgc cgaagatctc
    25261 cacaggagcc tc
//
