LOCUS       NZ_CP094483            21038 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces murinus strain JS029 chromosome.
ACCESSION   NZ_CP094483
VERSION     NZ_CP094483.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces murinus
  ORGANISM  Streptomyces murinus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Draft genome sequence of Streptomyces sp. JS029
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAR-2022) Agricultural Life Science, Sunchon National
            University, Jungangro 255, Suncheon, Jeonnam 57922, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-MAR-2021
            Assembly Method                   :: Unicycler v. 0.3.1
            Assembly Name                     :: JS029
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 164.82x
            Sequencing Technology             :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028753175.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 03:30:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,582
            CDSs (total)                      :: 7,481
            Genes (coding)                    :: 7,273
            CDSs (with protein)               :: 7,273
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 215
            CDSs (without protein)            :: 208
            Pseudo Genes (ambiguous residues) :: 0 of 215
            Pseudo Genes (frameshifted)       :: 110 of 215
            Pseudo Genes (incomplete)         :: 125 of 215
            Pseudo Genes (internal stop)      :: 20 of 215
            Pseudo Genes (multiple problems)  :: 41 of 215
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:08:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2754133
            Orig. end                         :: 2775171
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP094483.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from National Institute of
            Biological Resources.
FEATURES             Location/Qualifiers
     region          1..21038
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="19"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21038
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21038
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11038](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11038)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(624..639)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 21.06"
                     /tool="antismash"
     gene            776..1540
                     /locus_tag="ME763_RS11780"
                     /old_locus_tag="ME763_11765"
     CDS             776..1540
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973740.1"
                     /locus_tag="ME763_RS11780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11765"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_085566480.1"
                     /transl_table=11
                     /translation="MSTDVSSAENEAGTTVRTARVPKYYRLKKHLLDMTETQAPGTPVP
                     PERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRA
                     QGLEPTSQLLDVGYITADDRLAELLDISAGGRVLRIERLRMANGEPMAIETTHLSAKRF
                     PALRRSLVKYTSLYTALAEVYDVHLAEAEETIETSLATPREAGLLGTDVGLPMLMLSRH
                     SLDRAGLPVEWVRSVYRGDRYKFVARLKRPMD"
     gene            1676..1939
                     /locus_tag="ME763_RS11785"
                     /old_locus_tag="ME763_11770"
     CDS             1676..1939
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016437917.1"
                     /locus_tag="ME763_RS11785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11770"
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_172427629.1"
                     /transl_table=11
                     /translation="MPETPEVGPPVVTPLRVVIGICLVAPFVAMLWVGSYAKTDPTFIG
                     IPFFYWYQMVWVLISTALTMIAYKLWQHDQRSRRDAQGGAAK"
     gene            1936..3564
                     /locus_tag="ME763_RS11790"
                     /old_locus_tag="ME763_11775"
     CDS             1936..3564
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674905.1"
                     /locus_tag="ME763_RS11790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11775"
                     /product="sodium:solute symporter family protein"
                     /protein_id="WP_085566478.1"
                     /transl_table=11
                     /translation="MKTGVNGVALGVFIFFFLAVTVLGFLAARWRRAENEHTLDEWGLG
                     GRSFGTWITWFLLGGDLYTAYTFVAVPAAIYAAGASGFFAVPYTILVYPLIFTFLPRLW
                     SVSHRHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGG
                     DNTNGFVKDLPLLIAFAVLAAYTYSSGLRAPALIAFVKDGLIYLVILVAIIYIPIKLGG
                     FDDIFAKAAHAFSQVNPATGKPRGALAPAPAGQWTYATLALGSALALFMYPHSITATLS
                     SKSRNVIRRNTTILPLYSLMLGLLALLGFMAIAAGVKVTNGQLAIPQLFEDMFPDWFTG
                     VAFAAIGIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPKQEAQVSKFVSLLVKVGAL
                     IFVLGMDKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALLAGWAVGMVYGTLAAY
                     GVASPAQKHFGGSADDIPGIGQIGYIGMTAFVLNVLVTVVLTVVLKAVKAPEGVDETRP
                     EDYTADAGDPGVAVELPPATAGSAH"
     misc_feature    3659..3673
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 25.12"
                     /tool="antismash"
     misc_feature    3690..3704
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 23.4"
                     /tool="antismash"
     regulatory      3691..3826
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(3775..3792)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            3949..6306
                     /locus_tag="ME763_RS11795"
                     /old_locus_tag="ME763_11780"
     CDS             3949..6306
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378224.1"
                     /locus_tag="ME763_RS11795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11780"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_085566477.1"
                     /transl_table=11
                     /translation="MTIAPAEPASAQGLENDGPGTALLRTLTELTGDLPDADPGRVAAA
                     ALRGRSAHADETELRELATEAAAGLISEDPAYSRLAARLLTISIRAEAASQGVTSFTES
                     VAVGHREGLIADRTAEFTRIHAARLDDLIDRAADDRFGYFGLRTLHSRYLLRHPITRQV
                     IETPQHFMLRVAAGLAEDESARSVDEVAALYRLMSRLDYLPSSPTLFNSGTRHPQMSSC
                     YLLDSPLDELDSIYDRYHQVARLSKHAGGIGLSYSRIRARGSLIRGTNGHSNGIVPFLK
                     TLDASVAAVNQGGRRKGAAAVYLETWHSDLEEFLELRDNTGEDARRTHNLNLAHWVPDE
                     FMRRVNADGQWSLFSPADVPELVDLYGAEFDAAYREAERKGLAKKTMPARELYGRMMRT
                     LAQTGQGWMTFKDAANRTANQTAEPGQVIHSSNLCTEILEVTNDGETAVCNLGSVNLGA
                     FVVDGDIDWARLDETVRTAVTFLDRVVDINFYPTEQAGRSNAKWRPVGLGAMGLQDVFF
                     QLRLPFDSPEAKALSTRIAERIMLAAYEASADLAERSGPLPAWEQTRTARGVLHPDHYG
                     VEETWPERWAALRTRIAKVGLRNSLLLAIAPTATIASIAGVYECIEPQVSNLFKRETLS
                     GEFLQVNSYLVRDLKNLGVWDARTREALREANGSVQGFAWIPEEVRALYRTAWEIPQRG
                     LIDMAAARTPFLDQAQSLNLFMETPTIGKLSSMYAYAWKSGLKTTYYLRSRPATRIARA
                     AQAQKTIPVQQVADPDAVACSLENPESCEACQ"
     gene            6363..7373
                     /locus_tag="ME763_RS11800"
                     /old_locus_tag="ME763_11785"
     CDS             6363..7373
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047584.1"
                     /locus_tag="ME763_RS11800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11785"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_085566476.1"
                     /transl_table=11
                     /translation="MTRNQNLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVEEVDLHS
                     DVADLAKLSPAEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLSRQLFEEA
                     VHVQFYLTLLDTYLPDPEDRAAAFAAVENIPSIREKAEFCFKWIDSVDKIDRLETQSER
                     RRFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSFAFDV
                     VDTVRKEEPELFDDQLQQEVTDMLREAVEAELQFARDLCGDGLPGMNTDSMRQYLECVA
                     DQRLTRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVEGTVDLDEDF"
     gene            complement(7286..7528)
                     /locus_tag="ME763_RS11805"
                     /old_locus_tag="ME763_11790"
     CDS             complement(7286..7528)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973747.1"
                     /locus_tag="ME763_RS11805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11790"
                     /product="hypothetical protein"
                     /protein_id="WP_078967568.1"
                     /transl_table=11
                     /translation="MTGNQIQGLIGMTATLGILVLLVLPSVLGILRERRIDRQIRKAQE
                     AHGEKEAQKSSSRSTVPSTATWYADGRRSKKLVSS"
     gene            7621..8583
                     /locus_tag="ME763_RS11810"
                     /old_locus_tag="ME763_11795"
     CDS             7621..8583
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018544423.1"
                     /locus_tag="ME763_RS11810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11795"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_085566475.1"
                     /transl_table=11
                     /translation="MLKNVAAVLLNGVHPFELGVVCEVFGIDRSDEGLPVYDFAVVSAE
                     GPDLGTHCGFTVSTPHGLERLEAADLIAVPAGESYADRDYPPELLAALRRAVERGARVL
                     SVCSGVFVLAAAGLLDGRRCAVHWHHAEQLARRYPRLAVEQDVLYVDEDPVITSAGTAA
                     GIDACLHLVRKEQGPEVANKIARRMVVPPHRDGGQAQYIERPLPKAPCDTVGEVLVWME
                     EHLDLEVTVEQLAARAHMAPRTFARRFQQETGTTPYRWILRQRVLRAQELLEGSDETVD
                     AIAARTGFGTAAALRHQFVRALGTTPNAYRRAFRGPQAA"
     gene            complement(8631..10004)
                     /locus_tag="ME763_RS11815"
                     /old_locus_tag="ME763_11800"
     CDS             complement(8631..10004)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018544422.1"
                     /locus_tag="ME763_RS11815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11800"
                     /product="cytochrome P450"
                     /protein_id="WP_085566474.1"
                     /sec_met_domain="p450 (E-value: 4.3e-70, bitscore: 235.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESVQPETSVDPAELREPPLAGGAVPVFGHGLQLVRDPLDFMS
                     SLRAHGDIVRLRLGPKTVYAVTTPELTGALALSPDFKIDGPVWESLEGLLGKEGVATAN
                     GPLHRRQRRTMQPAFRMDAIPNYGPIMEEEAHALTERWRPGTPIDCTSESFRVAVRMAA
                     RCLLRGDFMDERAERLSTDLATVFRGMYRRMVVPLGPLYKLPFPANREFNRALADLHLL
                     VDEIVAERRASGQKPDDLLTALLEAKDDNGEPIGEQEIHDQVVAIITPGAETIASTIMW
                     LLQALAEHPEHAEKVRAEVESVTGGQPVGFEHVRSLRHTNNVILEAIRLRPAVWILTRR
                     AITDTALGEYRIPAGADIIYSPYAIQRDARSYDRHLDFDPDRWLPERAKEVPKYAMSPF
                     SVGNRKCPSDHFSMAQLSLITAAITAKYRFEPADDSDDSVRVGITLRPDNLRLRPLPW"
     gene            complement(10001..11038)
                     /gene="cyc1"
                     /locus_tag="ME763_RS11820"
                     /old_locus_tag="ME763_11805"
     CDS             complement(10001..11038)
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980387.1"
                     /locus_tag="ME763_RS11820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11805"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_172427796.1"
                     /sec_met_domain="T1TS (E-value: 1.3e-61, bitscore: 208.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPSLALPVIESGFPRRLHPYWPRLQEKTRLWLLEKRLMPEDKVR
                     EFADDLRYTDLMAGYYTDARDEVLQAIADYSAWFFVWDDRHDRDIVHARTGDWRRLRHR
                     LHAALDAPRHHLHHPDPLVAGFADSVLRLYGFLPSTWNQRFARHFHTVIEAYDREFRNR
                     TQGYVPGVDEYLALRRLTFAHWIWTDLLEPSAGCELPDAIRRNPSYRRAALLSQEFAAW
                     YNDLCSLPKEIAGDEVHNLGISLITYEGLTLEAAVDNIRRRVETCIDEFLAAEREVLRF
                     ADALADGTVRGKELSTAVRTCVGNMRNWFSSVYWFHHESGRYMVDSWADRSTPPYVTNE
                     AAGEK"
     misc_feature    11215..11232
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    complement(11274..11287)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            complement(11376..12026)
                     /gene="def"
                     /locus_tag="ME763_RS11825"
                     /old_locus_tag="ME763_11810"
     CDS             complement(11376..12026)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="ME763_RS11825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11810"
                     /product="peptide deformylase"
                     /protein_id="WP_085566472.1"
                     /transl_table=11
                     /translation="MAQQDTDQQHAGVLPVDDEGYVVDTEDCEEREKAWRESGTSRPIT
                     VVGNPVLHKECRDVTEFGEELRQLVADMFTSQRTAEGVGLAANQIGVDLKVFVYDCQDD
                     EGVRHVGAVCNPKLVDLPAERRRLDDNNEGCLSVPGAYAELARPDYAEVTGQDEQGNPI
                     KVRGTGYFARCLQHETDHLYGYLYIDRLSKRDRKDALRQMGENEPRYPVVAND"
     gene            complement(12099..13079)
                     /locus_tag="ME763_RS11830"
                     /old_locus_tag="ME763_11815"
     CDS             complement(12099..13079)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="ME763_RS11830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11815"
                     /product="tetratricopeptide repeat domain-containing
                     protein"
                     /protein_id="WP_046418611.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGELLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARAAGLRAVALLDRETGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLKVPGGATAAGEPLGMELGSAAVRLSPEGEAEVVWGRRLDPARIEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERTTSAGHSYPVFDEIELWAPSPVPTWVVLLEAATEADRD
                     ALEQLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGEGEHLDPHDHSEPGHPGPLGHR
                     TDGQLWVPERECGVAAPPSLVRGLLDGWVADSPDSRDWRDLEEVC"
     gene            complement(13296..13598)
                     /gene="rsrA"
                     /locus_tag="ME763_RS11835"
                     /old_locus_tag="ME763_11820"
     CDS             complement(13296..13598)
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136687.1"
                     /locus_tag="ME763_RS11835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11820"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_037660188.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCGEVLDHLYEFLDSEMPDVDRDKFRHHFEECSPCL
                     EKYGLEEAVKKLVKRCCGHDDVPADLRAKVMGRLDLIRSGQPAPDHDITSTAQDN"
     gene            complement(13595..14290)
                     /gene="sigR"
                     /locus_tag="ME763_RS11840"
                     /old_locus_tag="ME763_11825"
     CDS             complement(13595..14290)
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="ME763_RS11840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11825"
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_037660184.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTDNGQAEEPEGRGTSAEASAESTAERSARFERDAL
                     EFLDQMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINS
                     YRKKQREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKEALQAIPEEF
                     RIAVYLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARERGLVPAGAGE
                     SDEAKGSGS"
     gene            complement(14547..15173)
                     /locus_tag="ME763_RS11845"
                     /old_locus_tag="ME763_11830"
     CDS             complement(14547..15173)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973757.1"
                     /locus_tag="ME763_RS11845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11830"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_085566470.1"
                     /transl_table=11
                     /translation="MIEIVETDAGTARITWHRAAEPRAVLALSHGAGGGIEARDLVAIA
                     GVLPGHGVSVALVEQPWRVAGKKVAPAPKALDTGWRGIWPALAGMELPVISGGRSAGAR
                     VACRTARELGARAVLALSFPLHPPGRPEKSRADELLGTGVPTLVVQGGNDPFGGPAEFP
                     EGDFRMIEVPYGDHGFATPKRAGIGQERALEIITDAVVEWTASLA"
     gene            complement(15175..15990)
                     /locus_tag="ME763_RS11850"
                     /old_locus_tag="ME763_11835"
     CDS             complement(15175..15990)
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="ME763_RS11850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11835"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_085566469.1"
                     /transl_table=11
                     /translation="MCGRYAASRGPEDLAKTFGIERWEPEETLEPDYNVAPTKEVHVVL
                     DRPLKDADSPRPVRQLRTLRWGLVPSWSKSPEGGARMINARAETVHEKPSFRRAFAARR
                     CVVPADGYYEWVTGKQERELEVEGRKKRPRKQPYFVLPADGSVFAMAGLYEFWRDRTLP
                     EDHPQAWWVTCSVITTEAERTPLAVAPADGPRSLADIHPRMPLMLTPDRWDAWLDPSRT
                     DPEELRNLLAPPPPGLMRAYPVATAVSNVRNNGPELLKELEAPEEGTLF"
     misc_feature    16025..16039
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.88"
                     /tool="antismash"
     gene            16041..16763
                     /locus_tag="ME763_RS11855"
                     /old_locus_tag="ME763_11840"
     CDS             16041..16763
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992842.1"
                     /locus_tag="ME763_RS11855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11840"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_085566468.1"
                     /transl_table=11
                     /translation="MNSLAALAPSGLWDRLTGIQPDPDLWVVLATLAAALVVVVPHPLW
                     RVSRNAITIAHEGGHGLIALLTGRQLTGIRLHSDTSGLTVSRGKPYGLGMILTAAAGYI
                     APSLLGLGGAALLAAGRITLLLWAATALLAVMLVMIRNAYGVLTVVLAGGAFLLVSWLA
                     GPQVQAAFAYAVVWFLLFGGVRPPFELQSKRRRGEAGDSDADQLSRLTHVPAALWLFLF
                     HAVSLCSLIGGGRWLLEV"
     misc_feature    16841..16857
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.34"
                     /tool="antismash"
     gene            16859..18199
                     /gene="aroA"
                     /locus_tag="ME763_RS11860"
                     /old_locus_tag="ME763_11845"
     CDS             16859..18199
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674885.1"
                     /locus_tag="ME763_RS11860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11845"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_085566467.1"
                     /transl_table=11
                     /translation="MAPNTAPSALWPAPHASGAVDATVHVPGSKSVTNRALVLAALASE
                     PGWLRRPLRSRDTLLMAEALRAMGVEIEETVSSSSSVAGGPDGTGEAWRVLPTGLHGPA
                     TVDVGNAGTVMRFLPPVATLADGPIRFDGDPRSYERPLHGVIDALRRLGARIDDDGRGA
                     LPLTVHGGGALDGGPVSIDASSSSQFVSALLLSGPRFNQGVEVRHTGTSLPSMPHIRMT
                     VDMLRAVGAQVDTPESGGEPNVWRVTPGALLGRDLTIEPDLSNAQPFLAAALVTGGKVL
                     IPDWPERTTQPGDRLREIFTEMGGTCELTEFGLVFTGSGAIHGIDVDLSDVGELTPGIA
                     AVAALADSPSTLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLHIRPRALHGGTF
                     HTYEDHRMATAGAIIGLAVEGVRIENIGTTAKTLPDFPELWTGMLGQ"
     gene            18211..19221
                     /gene="rsgA"
                     /locus_tag="ME763_RS11865"
                     /old_locus_tag="ME763_11850"
     CDS             18211..19221
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rsgA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142295.1"
                     /locus_tag="ME763_RS11865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11850"
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="WP_085566466.1"
                     /transl_table=11
                     /translation="MRRYGKHTDEDDIRSRPNRKGNRPRTNIRPKHEDAAEGLVLTVDR
                     GRLTCLVEDRVVMAMKARELGRKAAVVGDRVMLVGDLSGMKDTLARIVRIQERSSVLRR
                     TADDDDPYERVVVANADQLAIVTALADPEPRPRLIDRCLVAAYDGGLDPLLVLTKSDLA
                     TPDELLELYGHLDIPYVVTSREELENGDAADRVREFLDGRITAFVGHSGVGKTTLVNAL
                     VPQERRRTTGHVNAVTGRGRHTTTSALALPLAGDGGWVIDTPGVRSFGLAHIDPSRVIL
                     AFPDLEPGTADCPRACSHDEPDCALDAWVAAGHADPARLYSLRRLLATRERTEGD"
     misc_feature    19278..19291
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            19306..19629
                     /locus_tag="ME763_RS11870"
                     /old_locus_tag="ME763_11855"
     CDS             19306..19629
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018845570.1"
                     /locus_tag="ME763_RS11870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11855"
                     /product="multidrug efflux SMR transporter"
                     /protein_id="WP_037660172.1"
                     /transl_table=11
                     /translation="MAWLLVIVAGVLETGFAVCLKLSHGFTRLWPTIAFASFALGSFGL
                     LTLSLRKLDVGPAYAVWTGIGATGTAIYGMIFLGDLVSTLKIVSISFVIVGIIGLQLSG
                     SSH"
     gene            19829..20080
                     /locus_tag="ME763_RS11875"
                     /old_locus_tag="ME763_11860"
     CDS             19829..20080
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS11875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ME763_11860"
                     /product="hypothetical protein"
                     /protein_id="WP_274506205.1"
                     /transl_table=11
                     /translation="MDAPADCVRATPREGGTGATRAMFPRLPRRMKSSARCAEVSAGLR
                     RLGAMCALSAPADRSDAAHERGDRPRRHGARYFLSSPY"
     gene            complement(20097..20690)
                     /locus_tag="ME763_RS11880"
                     /old_locus_tag="ME763_11865"
     CDS             complement(20097..20690)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016437896.1"
                     /locus_tag="ME763_RS11880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11865"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_085566464.1"
                     /transl_table=11
                     /translation="MAAARESLLDAAGAALARRPWPAVRMVEVAAAAGVSRQTLYNEFG
                     GKDGLARALVRRAADGYLAGVERALAGGGDDGERLTAVAEWTAAAAQQDALVRALLTGC
                     WSERLPAPPRGPAPVPAQRRPEPPLPSPPDLVRIVRDRAVSALSGPGTAPAATVELARS
                     CELVVRLALSCVTAPPGEGGIAGLIRTAAPRTAL"
ORIGIN
        1 gctcgacgaa tacgtggggc tgcccgccga gcaccccgag tcctatcgct cggtgctgcg
       61 ccgcgaggtg ctggagccgc tcggcatcgg catggactcc ttcctcggtc ccgacggcac
      121 ggccgaggac gtccaagcgg cgtgcgaggc gtacgaccgc gcgctcgccg cggccggcgg
      181 ggtggacctc cagctgctcg ggatcggcac cgacgggcac atcgggttca acgagccctg
      241 ctcctcgctc gcctcccgta cccggatcaa gaccctcacc gagcagaccc gcgtggacaa
      301 cgcgcgcttc ttcgacggcg agatcgagca ggtcccgcac cacgtcatca cccagggcat
      361 cggcaccatc ctggaggccc ggcacctggt gctgctcgcg accggcgagg gcaaggcgga
      421 cgcggtcgcg gcgaccgtcg agggcccggt ggcggccgtc tgcccggcct cggcgctcca
      481 gctgcacccg cacgccaccg tcgtcgtgga cgagccggcc gcctcgaagc tgaagctggc
      541 ggactacttc cggcacacgt acgcgaacaa gccggagtgg caggggatct aggggacgcg
      601 gacccggtgc ccaggggacc cctgttggac tagaccagct cgggtcccga cggtatacag
      661 aggggatcac ggagcgtgcg ggtggagtcc tgacacagta agccgtgcca cgatgtgagc
      721 cgtggccgat ggggatgtcg gtcgctttcg gcatccggag ccgggaaggc ggagcatgag
      781 caccgatgtc agcagtgcgg agaacgaggc cggcacgacc gtccgtaccg cgcgcgtgcc
      841 gaagtactac cgcctgaaga agcacctgct cgacatgacg gagacccagg cacccggcac
      901 accggtcccg ccggagcgca cgctggccgc ggagttcgac acctcccgca ccaccgtccg
      961 ccaggccctt caggagctgg tcgtggaggg ccgcctggag cgcatccagg gcaagggcac
     1021 cttcgtcgcc aagcccaagg tctcccaggc gctccagctc acctcctaca ccgaggacat
     1081 gcgcgcccag ggcctggagc cgacctccca gctgctggac gtcggctaca tcaccgccga
     1141 cgaccggctc gccgagctgc tggacatctc cgccggcggg cgggtgctgc gcatcgagcg
     1201 gctgcgcatg gccaacggcg agcccatggc catagagacc acccatctct ccgccaagcg
     1261 cttccccgca ctgcgccgtt cgctggtgaa gtacacgtcc ctctacaccg cgctcgccga
     1321 ggtgtacgac gtccatctcg ccgaggccga ggagaccatc gagacctcgc tggccacccc
     1381 gcgcgaggcc ggtctgctcg gtacggacgt cgggctgccg atgctgatgc tctcccggca
     1441 ctcgctggac cgcgcgggcc tgccggtcga gtgggtgcgg tcggtgtacc gcggcgaccg
     1501 gtacaagttc gtggcccgtc tgaagcgccc gatggactag agcctgtccg gaggcgttcg
     1561 ttccttcgcc gaatcgatac acacagcttg agacggggtc ttccactggc tggatagcgt
     1621 cacctagatt gcctgcgcat tacacaggtg atcagcgagg ggacggagcc gcagcatgcc
     1681 agaaacgccc gaagtaggac caccggtggt gacaccgctg cgcgtggtca tcggcatttg
     1741 tctcgtcgcg cccttcgtgg cgatgctgtg ggtcggctcc tacgcgaaga cggacccgac
     1801 gttcatcggc atcccgttct tctactggta ccagatggtc tgggtgctga tctccaccgc
     1861 cctcaccatg atcgcgtaca agctctggca gcacgaccag cgctcccgtc gtgacgcgca
     1921 ggggggtgcc gcgaagtgaa gaccggagtc aacggcgtcg cactgggcgt cttcatcttc
     1981 ttcttcctgg ccgtcacggt cctcggcttc ctcgccgcgc gctggcgccg ggccgagaac
     2041 gagcacacgc tggacgaatg ggggctgggc ggccgctcgt tcggcacctg gatcacgtgg
     2101 ttcctgctcg gcggcgacct gtacacggcc tacaccttcg tggccgtacc ggcggcgatc
     2161 tacgcggcgg gcgcgtccgg cttcttcgcg gtgccgtaca cgatcctggt ctacccgctg
     2221 atcttcacct tcctgccgcg gctgtggtcg gtctcgcacc ggcacggcta cgtcaccacc
     2281 tccgacttcg tgcgcgggcg gttcggctcg aagggcctgt cgctcgcggt cgcggtgacc
     2341 ggcatcctgg cgacgatgcc gtacatcgcg ctccagctcg tcggcatcca ggcggtgctg
     2401 gacgtgatgg gcgtcggcgg cggtgacaac accaacgggt tcgtgaagga cctgccgctg
     2461 ctgatcgcgt tcgcggtgct ggcggcgtac acgtactcct cgggtctgcg ggcgcccgcg
     2521 ctgatcgcgt tcgtcaagga cggtctgatc tacctcgtca tcctggtggc gatcatctac
     2581 atcccgatca agctgggcgg gttcgacgac atcttcgcca aggcggccca cgcgttcagc
     2641 caggtcaacc cggcaaccgg caagccgcgc ggggcgctcg cgccggcgcc cgccgggcag
     2701 tggacgtacg ccacgctggc gctcggttcc gcgctcgcgc tgttcatgta cccgcactcg
     2761 atcaccgcga cgctctcctc caagagccgt aacgtgatcc ggcgcaacac cacgatcctg
     2821 ccgctgtact ccctgatgct gggcctgctg gcgctgctgg gcttcatggc gatcgcggcc
     2881 ggggtgaagg tcaccaacgg gcagctggcg atcccgcagc tgttcgagga catgttcccg
     2941 gactggttca ccggtgtggc gttcgcggcg atcggcatcg gcgcgctggt gccggcggcg
     3001 atcatgtcga tcgcggcggc gaacctgttc acgcgcaaca tctacaagga cttcatcaag
     3061 ccggacgcca caccgaagca ggaggcgcag gtctccaagt tcgtgtcgct gctggtgaag
     3121 gtcggcgcgc tgatcttcgt actgggcatg gacaagacgg tcgccatcaa cttccagctg
     3181 ctgggcggca tctggatcct ccagaccttc ccggccctgg tcggcggtct gttcacccgc
     3241 tggttccacc gctgggcgct gctcgcgggc tgggcggtcg gcatggtcta cggcaccctc
     3301 gccgcgtacg gtgtcgcctc tccggcccag aagcacttcg gcggctccgc cgacgacatc
     3361 ccgggcatcg gccagatcgg ctacatcggc atgacggcct tcgtcctcaa cgtcctcgtc
     3421 acggtcgtcc tgaccgtcgt cctgaaggcc gtgaaggccc ccgagggcgt cgacgagacc
     3481 cgtcccgagg actacacggc ggacgccggc gacccgggcg tggcggtcga actgccgcct
     3541 gccacggcgg gcagcgcgca ctagcgagac gcccggggga cccgggcgac cagggacggg
     3601 ccggcggcgc caagggcgtc ggcggcccgt ttcgcatacc ccccgtagac acaaggtgac
     3661 acaacatctg ggggtggcat gacgacccgg cactagatgt atgctcatgg tcgctgtcgt
     3721 cgcaggggaa tccggtgcga atccggaact gtcccgcaac ggtgtacttg tgcgtatccg
     3781 cgcacaggaa tcagtccgag gacctgccgg cagcgcaccc ggcccaccgg ttcgggtgct
     3841 ctgagacgtc cgggcctcgc ggagtgggcc ggtggacgcg acgccctgtg cgctcgtgac
     3901 tgcccctgcc ctccgccagg ccccgtgccg agcgagggag agccccacgt gaccatcgcg
     3961 ccagccgaac cggcttcagc ccagggcctg gagaacgacg gtcccggtac cgcgctgctg
     4021 cggaccctga ccgagctgac cggggacctc cccgacgccg atccgggccg ggtcgccgcc
     4081 gccgcgctgc gcggccgctc cgcccacgcc gacgagacgg agctgcgcga gctcgcgacc
     4141 gaggccgcgg ccggactgat ctccgaggac cccgcgtact cccggctcgc cgcccggctg
     4201 ctgaccatct ccatccgcgc cgaggccgcc tcgcagggcg tgacgtcctt caccgagtcg
     4261 gtcgccgtcg gacaccgcga ggggctcatc gccgaccgga cggccgagtt cacccggatc
     4321 cacgccgccc ggctcgacga cctgatcgac cgcgccgccg acgaccgctt cggctacttc
     4381 ggtctgcgca ccctgcacag ccgctatctg ctgcgccacc cgatcacccg tcaggtcatc
     4441 gagacacccc agcacttcat gctgcgggtc gccgccggcc tcgccgagga cgagtcggcc
     4501 cgctcggtgg acgaggtcgc cgcgctctac cgcctgatga gccggctcga ctacctgccc
     4561 tcctccccca ccctgttcaa ctccggcacc cggcaccccc agatgtcgtc ctgctacctc
     4621 ctcgactccc cgctggacga gctggactcc atctacgacc gctaccacca ggtcgcgcgg
     4681 ctctccaagc acgccggcgg catcggtctg tcgtactccc gtatccgcgc ccgcggttcg
     4741 ctgatccggg gcaccaacgg gcactccaac ggcatcgtgc cgttcctgaa gacgctggac
     4801 gcctcggtgg ccgcggtgaa ccagggcggc cggcgcaagg gtgcggccgc ggtgtacctg
     4861 gagacctggc actccgacct ggaggagttc ctggagctgc gggacaacac cggtgaggac
     4921 gcccgccgta cgcacaatct gaacctcgcg cactgggtgc cggacgagtt catgcgccgg
     4981 gtcaacgccg acgggcagtg gtcgctgttc tccccggcgg acgtgcccga gctggtggac
     5041 ctgtacggcg cggagttcga cgccgcctac cgcgaggcgg agcgcaaggg tctcgcgaag
     5101 aagaccatgc cggcccgtga gctgtacggc cgcatgatgc gcaccctcgc gcagaccggc
     5161 cagggctgga tgacgttcaa ggacgccgcc aaccgcaccg ccaaccagac cgccgagccg
     5221 ggccaggtca tccactcctc caacctctgc acggagatcc tggaggtcac caacgacggc
     5281 gagacggcgg tctgcaacct gggctccgtc aacctcggtg ccttcgtggt cgacggggac
     5341 atcgactggg cgcgcctgga cgagaccgtg cgcacggccg tcaccttcct cgaccgcgtc
     5401 gtggacatca acttctaccc gaccgagcag gcgggccgct ccaacgccaa gtggcgcccg
     5461 gtgggcctcg gcgcgatggg tctccaggac gtcttcttcc agctgcggct gcccttcgac
     5521 tcccccgagg cgaaggcgct gtccacccgg atcgccgagc ggatcatgct cgccgcgtac
     5581 gaggcctcgg ccgacctcgc cgagcgcagc ggcccgttgc cggcctggga gcagacccgt
     5641 accgcgcgcg gggtgctgca ccccgaccac tacggcgtcg aggagacctg gcccgagcgc
     5701 tgggcggcgc tgcgcacccg gatcgcgaag gtcggcctgc gcaactcgct gctgctggcg
     5761 atcgcgccga cggccactat cgcctccatc gcgggcgtct acgagtgcat cgagccgcag
     5821 gtgtccaacc tgttcaagcg cgagacgctg tccggtgagt tcctccaggt caactcgtac
     5881 ctggtgcggg acctgaagaa cctgggcgtg tgggacgcgc gcacccggga ggcgctgcgc
     5941 gaggccaatg gctcggtgca gggcttcgcg tggatccccg aggaggtgcg ggcgctgtac
     6001 cgcacggcgt gggagatccc gcagcgcggt ctgatcgaca tggcggcggc gcgcaccccg
     6061 ttcctcgacc aggcgcagtc cctgaacctg ttcatggaga cgccgacgat cggcaagctc
     6121 tcctcgatgt acgcgtacgc ctggaagtcc gggctgaaga cgacgtacta cctgcgctcg
     6181 cgcccggcga cccgcatcgc ccgtgccgcc caggcgcaga agaccatccc cgtccagcag
     6241 gtcgccgacc ccgacgccgt cgcctgctcc ctggaaaacc ccgagtcctg cgaggcctgc
     6301 cagtaattcc cacccgccac ccgaccacca cccctggagg acggcgcttc gcgccgacag
     6361 caatgacccg taaccagaac ctgctcgacc cgggcttcga actgaccctg cgtcccatgc
     6421 gctacccgga cttctacgag cgctaccggg acgccatcaa gaacacctgg accgtggagg
     6481 aggtcgacct ccactcggac gtcgccgacc tcgcgaagct cagcccggcc gagcagcatc
     6541 tgatcggccg cctggtcgcg ttcttcgcga cgggtgactc gatcgtcgcc aacaacctgg
     6601 tgctgacgct gtacaagcac atcaactccc ccgaggcgcg gctctacctg agccgtcagc
     6661 tgttcgagga ggcggtgcac gtccagttct atctgacgct gctggacact tatctgcccg
     6721 acccggagga ccgcgcggcg gcgttcgcgg ccgtcgagaa catcccctcg atccgcgaga
     6781 aggccgagtt ctgcttcaag tggatcgact cggtggacaa gatcgaccgg ctggagacgc
     6841 agtcggagcg ccgccgcttc ctgctgaacc tgatctgctt cgccgcgtgc atcgagggcc
     6901 tgttcttcta cggcgccttc gcgtacgtct actggttccg cagccggggt ctgctgcacg
     6961 gcctggccac cggcaccaac tgggtgttcc gcgacgagac gatgcacatg tccttcgcct
     7021 tcgacgtggt cgacaccgtc cgcaaggagg agccggagct gttcgacgac cagctccagc
     7081 aggaggtcac cgacatgctg cgggaggccg tcgaggccga gttgcagttc gcgcgcgacc
     7141 tgtgcggtga cggcctcccg ggcatgaaca ccgactccat gcggcagtac ctggagtgcg
     7201 tggccgacca gcgtctgacc cggctgggct tcgcgccggt ctacggctcg gagaacccct
     7261 tctccttcat ggagctccag ggtgttcagg agctgaccaa cttcttcgag cgccgcccgt
     7321 cggcgtacca ggtggcggtg gagggcaccg tcgacctgga cgaggacttc tgagcctcct
     7381 tctccccatg ggcctcctgg gccttcctga tctgccggtc gatgcgccgc tcgcgcagga
     7441 tgccgagcac ggagggaagg accaggagga cgaggatccc gagggtcgcg gtcattccga
     7501 tcaggccttg gatctggttt ccggtcatgc cactactgtc ctgccggaca ctgctgaccg
     7561 ggagtggcag gactgccggg caccctcgaa ttactgccag ccctgaggca cactgggggc
     7621 atgctcaaga acgtggccgc tgtgctgctg aacggagtgc accccttcga gctgggcgtc
     7681 gtctgcgagg tgttcggcat cgaccgcagc gacgagggac taccggtgta cgacttcgcc
     7741 gtggtctcgg ccgaggggcc ggacctcggc acccactgcg ggttcaccgt gtccacgccg
     7801 cacggcctgg agcggctgga agcggccgat ctgatcgccg taccggccgg tgagagctat
     7861 gcggaccggg actatccgcc cgagctgctc gcggcgctgc gccgggccgt ggagcggggc
     7921 gcccgggtgc tcagcgtctg ctcgggggtg ttcgtgctgg ccgccgcggg gctgctggac
     7981 gggcgccggt gcgcggtgca ctggcaccat gccgagcagc tggcccggcg ctatccgcgg
     8041 ctcgccgtcg agcaggacgt gctctatgtg gacgaggacc cggtgatcac ctccgcgggc
     8101 accgcggccg gcatcgacgc ctgtctgcat ctggtgcgca aggagcaggg ccccgaggtc
     8161 gccaacaaga tcgcccgccg gatggtggtg cccccgcacc gggacggcgg ccaggcccag
     8221 tacatcgaac ggccgctgcc caaggccccg tgcgacaccg tcggcgaggt gctggtgtgg
     8281 atggaggagc acctcgatct ggaggtgacc gtcgaacagc tcgccgcccg cgcccatatg
     8341 gcgccgcgca ccttcgcccg gcgcttccag caggagacgg ggaccacgcc gtaccgctgg
     8401 atcctgcgtc aacgggtgct gcgcgcccag gagttgctgg agggcagtga cgagacggtg
     8461 gacgcgatcg ccgcgcgcac cgggttcggt acggcggccg cgctgcgcca ccagttcgtg
     8521 cgggcgctcg gtaccacccc gaacgcctac cggcgcgcgt tccggggccc gcaggccgcc
     8581 tgaacacgcg ccggtagcgg cacgcccctc ccggcgtcac ccgggctgtc tcaccagggc
     8641 agcggccgca gccgcagatt gtccgggcgc aacgtgatgc ccacgcgcac ggagtcgtcg
     8701 ctgtcgtcgg ccggttcgaa gcggtacttc gccgtgatcg ccgcggtgat caggctcagc
     8761 tgggccatgg agaagtggtc gctggggcac ttgcggttgc cgacgctgaa ggggctcatg
     8821 gcgtacttcg gcacctcctt ggcccgctcc ggaagccagc ggtccgggtc gaagtcgagg
     8881 tggcggtcgt acgagcgggc gtcgcgctga atggcgtacg ggctgtagat gatgtcggcc
     8941 ccggccggaa tgcgatactc ccccagcgcg gtgtcggtga tcgcccggcg cgtcagaatc
     9001 catacggcgg ggcgcagccg gatggcctca aggatcacat tgttggtgtg cctgagggag
     9061 cggacgtgct cgaatccaac cggctgacca ccggtcacgg attcaacctc ggcacgtacc
     9121 ttctcggcat gctccgggtg ttccgccagc gcctggagca accacatgat cgtggacgcg
     9181 atcgtttcgg cgccgggggt gattatcgcg acgacctggt cgtggatctc ctgttccccg
     9241 atgggctccc cattgtcgtc cttcgcttcc agcaatgccg tcagcaaatc gtccggcttt
     9301 tgaccagatg ccctccgctc ggcgacgatc tcgtccacga gcagatgcaa atcggccaat
     9361 gcgcgattga attcgcgatt ggccggaaac ggcagcttgt acaggggccc cagcggcacc
     9421 accatcctgc ggtacatacc gcggaagacg gtggcgaggt cggtgctcag ccgctcggcg
     9481 cgctcgtcca tgaagtcgcc gcgcagcagg cagcgggcgg ccatgcgcac cgccacccgg
     9541 aaggactccg aggtgcagtc gatgggggtg ccggggcgcc agcgctcggt cagcgcgtgc
     9601 gcctcctcct ccatgatcgg gccgtagttg ggtatggcgt ccatccggaa cgcgggctgc
     9661 atggtgcgcc gctgacggcg gtgcaggggg ccgttggcgg tggccacgcc ctccttgccg
     9721 agcaggccct ccagcgactc ccacaccggg ccgtcgatct tgaagtcggg gctgagggcg
     9781 agcgcgcccg tcagttccgg ggtggtgacg gcgtacacgg tcttggggcc gagccggagg
     9841 cgcacgatgt cgccgtgggc gcgcagcgag gacatgaagt ccagcgggtc gcgcaccagt
     9901 tggaggccgt gtccgaagac cgggacggcg ccgccggcca ggggtggttc acgcagctcc
     9961 gccgggtcga cggaggtctc gggctgcacg gactctacgg tcatttctca cctgccgctt
    10021 cgttggtgac gtacgggggc gtggagcggt cggcccaact gtccaccatg taacggccgg
    10081 actcgtggtg gaaccagtag accgagctga accagttgcg catattgccg acgcaggtac
    10141 ggacggcggt gctcaattcc tttccgcgga ccgtgccgtc ggccagtgca tccgcgaacc
    10201 tgagtacttc gcgttcggct gcgaggaatt catcgatgca ggtctcgacg cgccgcctga
    10261 tattgtcgac cgccgcttcg agcgtcagcc cctcataggt gatgagactg attccgagat
    10321 tgtggacctc atcgcccgct atttccttcg ggagcgagca cagatcgttg taccaggcgg
    10381 cgaattcctg actgagcaat gcggcccgcc gataggaggg gtttcgcctt atggcgtcgg
    10441 ggagttcgca tccggcactg ggttcgagca ggtccgtcca gatccagtgc gcgaaggtga
    10501 gccggcgcag ggcgagatac tcgtcgacgc cgggcacata tccctgggtg cgattgcgga
    10561 attcacggtc gtacgcctcg atgaccgtgt ggaaatgccg ggcgaagcgc tggttccagg
    10621 tgctcggcag gaagccgtag agccgcagca cgctgtcggc gaacccggcg accagcgggt
    10681 ccgggtggtg cagatggtgc ctgggtgcgt cgagtgccgc gtgcagccgg tggcgcagcc
    10741 gccgccagtc gcccgtgcgc gcgtgcacga tgtcgcggtc gtgccggtcg tcccagacga
    10801 agaaccaggc gctgtagtcc gctatggcct ggagcacctc gtcgcgggcg tccgtgtagt
    10861 agcccgccat gaggtcggtg tagcgcagat cgtcggcgaa ctcccgcacc ttgtcttccg
    10921 gcatcagccg cttttccagc agccacagcc gggtcttctc ctggagccgc ggccaatacg
    10981 gatgcagtcg ccggggaaag ccggactcga tcaccgggag tgccagtgag ggtggcacca
    11041 cgaccgccgt cgtcgtccct gtggtgctgc gtgggaaagc ttgcacagaa caaacccctc
    11101 tcagccgccg gatacgcacc cgctcgggtg gggccggtac gtctcgttgc ctatcccgca
    11161 cttcccattc agcaccacaa ctgaccgccg tgggaacgga tttgcgcccc tcactacccc
    11221 atggtgccga gattcctccc ctgcgtgact gattaatgat caccagcacc acagaaacga
    11281 ccatttgtgc gacgcactga tgagcgaaga agggcaagaa gaagggcgcc gggccgggag
    11341 tggtcccggc ccggcgccca acggcccgac agagcctagt cgttggcgac cacggggtag
    11401 cgcggctcgt tctcgcccat ctgtcgcagc gcgtccttgc ggtcacgctt ggacagccgg
    11461 tcgatgtaga ggtagccgta gaggtggtcg gtctcgtgct gcaaacaccg tgcgaagtat
    11521 ccggtgccgc ggaccttgat cgggttgccc tgctcgtcct ggccggtcac ctcggcgtag
    11581 tcgggacgcg ccagctcggc gtaggccccg ggcaccgaca gacagccctc gttgttgtcg
    11641 tcgagccggc gccgctcggc gggcaggtcg accagcttcg ggttgcacac cgcgcccacg
    11701 tgccggacgc cctcgtcgtc ctggcagtcg tagacgaaga ccttcagatc gacgccgatc
    11761 tggttggcgg ccaggcccac gccctcggcg gtgcgctggc tggtgaacat gtcggcgacc
    11821 agctgccgca gttcctcgcc gaactcggtg acgtccctgc actccttgtg cagcaccgga
    11881 ttgccgacga ccgtgatcgg ccgcgaggtg ccgctctccc gccaggcctt ctcgcgctcc
    11941 tcgcagtcct ccgtgtccac gacatagccc tcgtcgtcga cggggagcac gcccgcgtgc
    12001 tgctgatcgg tgtcctgctg cgccatgacc gacgtacgcc ttcctgcaag cctggaaaat
    12061 tctgcgtgta cagcctaaag gggccggtca cccgctgctc agcaaacctc ttccagatcc
    12121 cgccagtccc tcgaatccgg gctgtcggcg acccatccgt ccagcagccc gcgcaccagc
    12181 gaaggcggcg cggccacccc gcactcccgc tccggcaccc acagctgccc gtccgtgcgg
    12241 tggcccaggg ggcccgggtg gcccggttcg ctgtggtcgt gggggtccag gtgctccccc
    12301 tcgccctcgt cggacggcat ccgggactcg ctgcacatcc ggcacagcag ccgtaccgag
    12361 gacgaccagt cctccgcggc gaacccggcg tccgcggcca gctgctccag cgcgtcgcgg
    12421 tccgcctcgg tggccgcctc caggaggacc acccaggtgg gcaccggcga gggcgcccac
    12481 agctcgatct cgtcgaagac ggggtaactg tgcccggcgg acgtggtgcg ctccccgtgc
    12541 gggacaccgt cgtgcagcac gacctcgccc cagcgccgcc ccgaggaggg cagcgggatg
    12601 gacagcacct cgatccgcgc ggggtccagc cggcggcccc agaccacctc ggcctcgccc
    12661 tccggtgaga gccgtacggc cgcgctgccc agctccatgc cgagcggttc cccggcggcg
    12721 gtcgcgcccc cgggcacctt gaggccgtac gcctgccagg cgcggcgggc cagcggccag
    12781 tcctggaggg cggtcgcggc gatgcccacg ttccaccagt cgggggcgcc ggtctcgcgg
    12841 tcgaggaggg cgacggcgcg cagtccggcg gcgcgggcct gctcccagtc gtgccggaac
    12901 ttgtgcagca gcgcgaggtt gaaccaggac tccgacagcc agggttccag gtcggcggcg
    12961 cgggtcagca gttcgcccgc gtcctcgtac cggccgtcgc cgatgagcgt gaacgcgcgg
    13021 tcggtggcct gccgccagga ggcggagggc cggtgccgtc ccttgccgaa gatcctcacg
    13081 attcccgcct gccagttcca gttccgcaca gtgggctggc ttgtgccccc aggcgccctc
    13141 tccctcgcat ccaaccacgt gcggtgggaa cggcgctcat tacccatggg ttacccaggt
    13201 gcgggcggga tcagacagtg ccgtacgtct cgcccgagcc ggggcgaagc cgggcggacg
    13261 cgacggaggg tgcggggcgc gggcggcgcg cggcctcagt tgtcctgggc cgtggaggtg
    13321 atgtcgtggt cgggcgcggg ctgtcccgag cggatcaggt ccagtcgtcc catgaccttg
    13381 gcgcgcaggt cggcgggcac gtcgtcatgg ccgcagcacc gcttgaccag cttcttcacg
    13441 gcctcttcca ggccgtactt ctccaggcac ggcgagcact cctcgaagtg gtgccggaac
    13501 ttgtcgcgat cgacgtccgg catctcgctg tcgaggaact cgtacagatg gtccaggacc
    13561 tcaccgcagt ccgtctcgtg cggctctccg cagctcatga gcccgagcct ttcgcttcgt
    13621 ccgactcccc ggcgcccgcc gggaccagcc cgcgctcacg ggcgtagtcc tccagcatgc
    13681 cgcgcagttg acggcggccg cggtgcagcc gggacatcac cgtaccgatg ggtgtcccca
    13741 tgatgtccgc gatctccttg taggcaaacc cctccacatc cgcgagatac acggcgatgc
    13801 ggaactcctc ggggatcgcc tggagcgctt ccttcacatc cgagtcgggc agatggtcga
    13861 gcgcctgcga ctcggcggag cgcagccccg tcgacatgtg cgactcggct cgggcgagct
    13921 gccagtcctc gatctcctcc gcggcggaac gctggggctc acgctgcttc ttgcggtacg
    13981 agttgatgaa ggtgttggtg aggatccggt acagccacgc cttgaggttg gtgccctcgc
    14041 ggaactggtg gaaggaggcg taggccttgg cgtacgtctc ctgtacgagg tcctcggcgt
    14101 cggccgggtt gcgcgtcatg cgcagggcgg ccgagtacat ctggtcgagg aactcgagcg
    14161 cgtcccgctc gaagcgcgcg ctgcgctccg cggtcgactc ggcggacgcc tccgcgctcg
    14221 tgccccggcc ctcgggctct tccgcctggc cgttgtcggt ccccgcgtcg gtccctgtga
    14281 ccggacccac ctcctcaaga tcccgggcag gaccgagagt ggtcccactc gattcggagg
    14341 atagaacacg acccgtaccc gccgcccctc gaattgaggc ggtcttgggc gcgcgcagca
    14401 ccgtccagtc cagctcagcg ccggtctgac gggccgggca gatggtcgaa cccatgcggc
    14461 ggacttccct tccgacgacg tcggtgccga ggcctcagca ctcctgtgcg tcacaacagc
    14521 gctgcggcgc gcagcattcc cgggggtcac gcgagtgacg cggtccactc cacgacggcg
    14581 tcggtgatga tctccagggc ccgttcctgg ccgatcccgg cgcgtttggg ggtcgcgaag
    14641 ccgtggtcgc cgtagggcac ctcgatcatc cggaagtcac cctcggggaa ctcggcgggc
    14701 ccgccgaagg ggtcgttgcc gccctgtacg acgagggtgg gcacaccggt gccgagcagt
    14761 tcgtccgcac gggacttctc gggcctgccc ggcgggtgca gcgggaagct cagggcgagg
    14821 acggcgcggg cgcccagttc gcgggcggta cggcaggcga cgcgggcgcc ggcgctgcgg
    14881 ccgccggaga tcaccggcag ctccatgccg gccagcgcgg gccagatccc gcgccatccg
    14941 gtgtccagcg ccttcggggc gggcgccacc ttcttgcccg cgacccgcca gggctgttcg
    15001 acgagggcca cgctcacccc gtgcccgggc aggaccccgg cgatcgccac gaggtcacgc
    15061 gcctcgatcc cgccgcccgc gccatggctc agcgcgagga cggcccgggg ctcggcggcc
    15121 cggtgccagg tgatgcgggc ggttccggcg tcggtctcga caatctcgat cacgctagaa
    15181 gagtgtgccc tcttcggggg cctccagctc cttcagcagc tccgggccgt tgttgcggac
    15241 gttgctgacg gcggtggcga ccgggtaggc gcgcatcagg ccgggcgggg gcggggcgag
    15301 caggttccgc agttcctcgg ggtcggtgcg ggaggggtcg agccaggcgt cccagcggtc
    15361 cggggtgagc atcagcggca tccgggggtg gatgtcggcg agcgagcgcg gtccgtcggc
    15421 gggggccacg gccagcgggg tccgctcggc ctccgtggtg atcaccgagc aggtgaccca
    15481 ccaggcctgg gggtggtcct cgggcagcgt ccggtcccgc cagaactcgt acaggccggc
    15541 catcgcgaac acggaaccgt cggcgggcag cacgaagtac ggctgcttgc ggggccgctt
    15601 cttgcgcccc tcgacctcca gctcgcgctc ctgcttcccg gtcacccact cgtagtagcc
    15661 gtcggcgggc acgacgcaac ggcgggcggc gaaggcacgg cgaaaggacg gcttctcgtg
    15721 cacggtctcc gcgcgggcgt tgatcatccg ggcgccgccc tcggggctct tcgaccagga
    15781 cggcaccagt ccccacctga gcgtgcgcag ctggcgaacc ggacgcgggg agtccgcgtc
    15841 tttcaaggga cggtcgagca cgacgtggac ctctttggtg ggggccacgt tgtagtccgg
    15901 ctccagggtc tcctcgggtt cccacctctc gatcccgaag gttttggcga ggtcctcggg
    15961 cccacgactg gctgcatacc gtccgcacat acgtgccaca ctgccagact ccgcccgcca
    16021 ccagggagcc actcggacac atgaacagcc tcgccgccct cgcgccgtcc ggcctctggg
    16081 accggctcac cggtatccag cccgaccccg atctgtgggt ggtgctcgcc accctcgccg
    16141 ccgccctggt ggtcgtcgta ccgcatccgc tgtggcgggt gtcgcgcaac gcgatcacca
    16201 tcgcgcacga gggcggccac gggctgatcg ccctgctcac cggccggcag ctcaccggta
    16261 tccggctgca ctccgacacc agcgggctca cggtgagccg gggcaagccg tacgggctcg
    16321 gcatgatcct caccgccgcc gcgggctaca tcgcgccctc gctgctcggc ctcggcggcg
    16381 cggccctgct cgccgcgggc cgcatcacgc tgctgctgtg ggcggcaacg gccctgctcg
    16441 cggtgatgct ggtgatgatc cgcaacgcgt acggcgtgct caccgtggtg ctcgcgggcg
    16501 gggcgttcct cctggtgtcg tggctcgcgg ggccgcaggt gcaggcggcg ttcgcgtacg
    16561 ccgtggtgtg gttcctgctg ttcgggggcg tacgaccgcc gttcgagctg cagagcaagc
    16621 ggcgccgggg cgaggccggc gactcggacg cggaccagct gtcccggctg acgcatgtcc
    16681 cggcggccct gtggctgttc ctgttccacg ccgtgtccct gtgctcgctg atcggcggcg
    16741 ggcgctggct gctggaggtc tgaggacacc cggccaccgg ggtccacagg ccgttcgtcc
    16801 cggacggcgg ggcggttgcc ggaaggttgc ggccccgccc tccttataaa gtgggcccat
    16861 ggccccgaac accgccccct ccgccctctg gcccgctccg cacgcgagcg gcgccgtcga
    16921 cgccaccgtc catgtgccgg ggtccaagtc ggtcaccaac cgcgccctgg tgctggccgc
    16981 cctcgcctcc gagcccggct ggctgcgccg cccgctgcgc tcccgggaca ccctgctgat
    17041 ggcggaggcc cttcgggcca tgggcgtgga gatcgaggag acggtgtcgt ccagctcctc
    17101 cgtcgcgggg ggccccgacg gcaccggcga ggcctggcgg gtgctgccga ccggcctgca
    17161 cggcccggcc acggtggatg tcggcaacgc gggcaccgtg atgcgtttcc tgccgccggt
    17221 ggccacgctg gccgacggcc ccatccggtt cgacggcgac ccgcggtcgt acgagcgtcc
    17281 gctgcacggt gtgatcgacg cgctgcgccg gctcggcgcg cggatcgacg acgacggccg
    17341 gggcgcgctg ccgctgaccg tgcacggcgg cggggcgctg gacggcggcc cggtgtcgat
    17401 cgacgcgtcg tcctcctcgc agttcgtctc cgcgctgctg ctctccggcc cccgcttcaa
    17461 ccagggcgtc gaggtccggc acaccggcac cagcctgccc tcgatgccgc acatccggat
    17521 gacggtggac atgctgcgcg cggtcggcgc ccaggtggac accccggagt cgggcggcga
    17581 gccgaacgta tggcgggtga cgccgggcgc gctgctcggc cgggacctga cgatcgagcc
    17641 ggacctgtcc aacgcgcagc cgttcctggc ggcggccctg gtgaccggcg gcaaggtcct
    17701 gatcccggac tggccggagc gcaccaccca gccgggtgac cggctgcggg agatcttcac
    17761 cgagatgggc ggcacctgcg aactcaccga gttcgggctg gtgttcaccg gttccggcgc
    17821 gatccacggc atcgatgtcg acctgagcga cgtcggcgag ctgaccccgg gcatcgcggc
    17881 cgtcgccgcg ctcgccgact ccccttcgac gctgcgcggg gtggcccatc tgcggctgca
    17941 cgagacggac cggctggccg cgctcaccaa ggagatcaac gagctcggcg gtgacgtcac
    18001 ggagacggcc gacggtctgc acatccgccc gcgcgctctg cacggcggca ccttccacac
    18061 ctacgaggac caccgcatgg ccaccgccgg cgcgatcatc ggcctggcgg tcgagggcgt
    18121 acgcatcgag aacatcggga cgacggccaa gaccctgccg gacttccccg agctgtggac
    18181 cgggatgctc gggcagtagg gacacacgcc atgcgccgct acggcaagca caccgacgag
    18241 gacgacatcc gctcccgccc caaccgcaag ggcaaccggc cgcggacgaa catccggccc
    18301 aagcacgagg acgcggccga ggggctggtc ctgaccgtgg accgggggcg gctgacctgc
    18361 ctggtggagg accgggtggt gatggcgatg aaggcgcggg agctgggccg caaggcggcg
    18421 gtggtcgggg accgggtgat gctggtcggc gatctgtccg gcatgaagga cacgctcgcg
    18481 cggatcgtcc ggatccagga gcggtcctcg gtgctgcggc gcacggcgga cgacgacgat
    18541 ccctacgagc gcgtggtggt cgccaacgcc gaccagctgg cgatcgtcac ggccctcgcc
    18601 gacccagagc cgcggccccg gctgatcgac cgctgtctgg tcgcggcgta cgacggggga
    18661 ctcgaccccc tgctggtgct gaccaagtcc gacctggcca cgccggacga actcctggag
    18721 ctgtacggcc atctggacat cccgtacgtg gtcaccagcc gcgaggagct ggagaacggg
    18781 gacgcggcgg accgggtgcg ggagttcctg gacgggcgga tcaccgcgtt cgtggggcac
    18841 tccggcgtgg gcaagacgac gctggtgaac gcgctggtgc cgcaggagcg gcggcgtacg
    18901 acgggacacg tcaacgcggt gacggggcgc ggccggcaca ccaccacctc ggcactggcg
    18961 ctgccgctgg cgggcgacgg cggctgggtg atcgacactc cgggcgtacg gtccttcggc
    19021 ctggcgcaca tcgatccgtc ccgggtcatc ctcgccttcc cggacctgga gcccggtacg
    19081 gcggactgcc cgcgcgcgtg cagccatgac gagccggact gcgcgctgga cgcgtgggtg
    19141 gcggcggggc acgcggatcc ggcgcggctg tactcgctgc ggcggctgct ggcgacgcgg
    19201 gagcgcacgg agggcgactg accttcgcgt tgtttgcccg ggccgcggtg cggcaagtgc
    19261 ataatcgcac cgggccggag atccggatca acgggaggac agcgcatggc gtggctgctg
    19321 gtcatcgtgg ccggagtgct ggagaccggc ttcgccgtgt gcctcaagct ctcccacggc
    19381 ttcacccggc tgtggccgac catcgccttc gcctccttcg cgctcggcag cttcggcctg
    19441 ctgaccctct cgctgcgcaa actcgacgtc ggccccgcgt acgccgtctg gaccggcatc
    19501 ggcgcgaccg gcacggcgat ctacggcatg atcttcctgg gcgacctggt ctccaccctg
    19561 aagatcgtct cgatcagctt cgtgatcgtg gggatcatcg gcttgcagct gtcggggtcg
    19621 agccactagt tcggcgagct gttgttccgg ccgcgccggc tgatctgcgg cggggtgcgg
    19681 cgcccgtgcc gcgtggacgg cttcgtgccg ggacggcggg ctggtcgccg cccgactcgg
    19741 gggcacgcgg gagccgttct ccggatggcc gctctggtcg cagacccgct gcgcggggcg
    19801 cgtcctgtgg gcctgcaacg cggaacacgt ggacgccccg gccgactgcg tccgcgccac
    19861 cccgcgcgag ggcggcaccg gggcgacgcg ggcgatgttc ccccggctgc cgcgccggat
    19921 gaagtcctcg gcacggtgcg cggaggtgtc ggccggtctg cgccggctgg gcgcgatgtg
    19981 cgccctctcg gctccggcgg accggtccga cgcggcccac gagcggggcg accggccgcg
    20041 gcgccacggg gcccggtact tcctaagttc cccgtactga cggcggttgg ggccggtcag
    20101 agcgccgtgc ggggtgcggc ggtccggatc aggccggcga tcccgccctc ccccggtggc
    20161 gccgtgacgc aggagagggc gaggcggacg accagttcgc aggagcgggc cagttcgacg
    20221 gtggcggcgg gggccgtgcc ggggccggac agcgcgctga cggcgcggtc gcggacgatc
    20281 cgtacgagat cgggcggcga ggggagcggc ggttccggac ggcgctgcgc cggtaccggg
    20341 gcggggcccc ggggcggtgc ggggagccgc tcgctccagc agccggtgag caacgcccgt
    20401 accagcgcgt cctgctgggc cgcggccgcc gtccactcgg cgacggcggt gagccgctcc
    20461 ccgtcgtcgc cgccgcccgc gagggcgcgc tccacaccgg cgagatagcc gtcggccgcc
    20521 cgccgcacca gcgcccgcgc gaggccgtcc ttgccgccga actcgttgta cagggtctgc
    20581 cgggacacgc ccgccgccgc ggccacctcc accatgcgca ccgcgggcca cggccggcgc
    20641 gccagcgccg cgccggcggc gtccagcaag gattcccggg cagcagccat cgtcgtctcc
    20701 ctggagtcaa cggcgttccg cccagatttg acggactttc ggatgatgtc aaggggttgc
    20761 tcgccgggag cggaaggccc tgtaccgcgt gcggacgcac ggcggtcgcg cacgccgtca
    20821 cgggcgccgc gcacggccgg ttcgacacac gtacgccccc ggtggctccc gtacccgccc
    20881 agccgatagc gtgacgtaca tgcccgacta cctcgacgac ctccgtctcg cccacgtcct
    20941 cgcggacgcg gccgacgcgg ccaccatgga ccgcttcaag gccctggacc tgaaggtgga
    21001 gacgaagccg gacatgacgc cggtgagcga agcggaca
//
