LOCUS       NZ_CP094483            21137 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces murinus strain JS029 chromosome.
ACCESSION   NZ_CP094483
VERSION     NZ_CP094483.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces murinus
  ORGANISM  Streptomyces murinus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Draft genome sequence of Streptomyces sp. JS029
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAR-2022) Agricultural Life Science, Sunchon National
            University, Jungangro 255, Suncheon, Jeonnam 57922, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-MAR-2021
            Assembly Method                   :: Unicycler v. 0.3.1
            Assembly Name                     :: JS029
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 164.82x
            Sequencing Technology             :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028753175.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 03:30:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,582
            CDSs (total)                      :: 7,481
            Genes (coding)                    :: 7,273
            CDSs (with protein)               :: 7,273
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 215
            CDSs (without protein)            :: 208
            Pseudo Genes (ambiguous residues) :: 0 of 215
            Pseudo Genes (frameshifted)       :: 110 of 215
            Pseudo Genes (incomplete)         :: 125 of 215
            Pseudo Genes (internal stop)      :: 20 of 215
            Pseudo Genes (multiple problems)  :: 41 of 215
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:08:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2731964
            Orig. end                         :: 2753101
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP094483.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from National Institute of
            Biological Resources.
FEATURES             Location/Qualifiers
     region          1..21137
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="18"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21137
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21137
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11137](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11137)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            1803..2348
                     /locus_tag="ME763_RS11660"
                     /old_locus_tag="ME763_11645"
     CDS             1803..2348
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024854.4"
                     /locus_tag="ME763_RS11660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11645"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_274506204.1"
                     /transl_table=11
                     /translation="MTGVDPALDVIERQTAVLMRNFELLHRRTDVHDRLDRAQYLLLRT
                     LSDGGPMTITTLACTLGLDPSTAGRQVSALTAAGLVERTADPADRRRWVVTPTADGLRE
                     MRVVRDRRTESHAELLGDWDPEDLRTLGTMLDRYNRAVAARYLLTPPTEAATEASTGTV
                     ARARTADPAETPAITSPA"
     gene            complement(2504..2989)
                     /locus_tag="ME763_RS11665"
                     /old_locus_tag="ME763_11650"
     CDS             complement(2504..2989)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024212.4"
                     /locus_tag="ME763_RS11665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11650"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_085566495.1"
                     /transl_table=11
                     /translation="MDRRVDPMEPEMDPEGRAALDGLYTALSALAYTMTGNRAHSRLRR
                     EAGVSVDRASLAVLRVLAASPEPLRMGELAAALMVNAPHVTREVRRLEDGGLVATTREP
                     GDQRARRARATGEGREAVARAEATGKRWLGEALGEFSPEELETAAAVINRIVAGFRP"
     misc_feature    complement(3078..3095)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 18.9"
                     /tool="antismash"
     misc_feature    complement(3083..3099)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.81"
                     /tool="antismash"
     misc_feature    3087..3103
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.39"
                     /tool="antismash"
     misc_feature    complement(3102..3115)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.54"
                     /tool="antismash"
     gene            3133..4377
                     /locus_tag="ME763_RS11670"
                     /old_locus_tag="ME763_11655"
     CDS             3133..4377
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044351.1"
                     /locus_tag="ME763_RS11670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11655"
                     /product="cytochrome P450"
                     /protein_id="WP_085566494.1"
                     /sec_met_domain="p450 (E-value: 6.7e-22, bitscore: 76.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPETPTAPPVPAPAPAAPPAYSTHRAPGCPFDPPPERHRLLTEGP
                     LARISLWDGNTAWLVTRHADQVALLRDERISADNRLPNFPSVSAGSQATRAHNRTFISM
                     DEPEHNEQRRRFTADFTVKRINELRPRIEAIVTELLDAMEQAGPPADLVRDFALPLPSL
                     VICELLGVPYTDHAFFQRVSAVMIDTRSTPEVALAASQELVDYLGDLVAAKEKDPGDDL
                     LSRMAVQYLRTGISTRDECAKQARLLLVAGHETTANMIALGVCALLQHPEQLAAVRDGE
                     PRRVVNAVEELLRYLTIVHLGRRRVAVADVAVGGQVIRAGEGVVFATDLANRDPEVFED
                     PDRLDIDRAARRHIAFGTGPHQCLGQNLARMELQVAYPALLRRFPGLRLERPLTQIPFR
                     EDMAVYGVYELPVAW"
     misc_feature    4416..4429
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.39"
                     /tool="antismash"
     misc_feature    complement(4440..4453)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.39"
                     /tool="antismash"
     gene            4536..4946
                     /locus_tag="ME763_RS11675"
                     /old_locus_tag="ME763_11660"
     CDS             4536..4946
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019061090.1"
                     /locus_tag="ME763_RS11675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11660"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_085568736.1"
                     /transl_table=11
                     /translation="MKRLRARLRAESGQHATGLTATQLAVLAEVVREGPVTAARLAALE
                     HVTPQAIAQSLAVLKAAGLVHGAPDPRDGRRKLISADPSAGALIERLLAGRATFLARAI
                     TQVVRPEERDDLEKAVELLERLAGAEIHPHIP"
     gene            4969..5568
                     /locus_tag="ME763_RS11680"
                     /old_locus_tag="ME763_11665"
     CDS             4969..5568
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173702.1"
                     /locus_tag="ME763_RS11680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11665"
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="WP_085566493.1"
                     /transl_table=11
                     /translation="MTSPAALPVIDPARTALLAMDLQGGILPLVPDPDALVERVKGAIA
                     DVRAAGGAIGYVRVAFTEDDWAAIPETNKSFSPLAAAKRNHHEDPDTQVDARIAPEAGD
                     IVVRKVRIGAASTTDLYERLRERGIDTLILSGISTSGVVLSTLTDAADRDYRVIVLSDG
                     VADRDQEVHRVLLEKVFPMRSYVIDIAELRELLGVA"
     gene            complement(<5827..6591)
                     /locus_tag="ME763_RS11685"
                     /old_locus_tag="ME763_11670"
                     /pseudo=""
     CDS             complement(<5827..6591)
                     /NRPS_PKS="Domain: Abhydrolase_1 (59-151). E-value:
                     8.7e-10. Score: 30.5. Matches aSDomain:
                     nrpspksdomains_ME763_RS11685_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF023568.4"
                     /locus_tag="ME763_RS11685"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11670"
                     /product="alpha/beta fold hydrolase"
                     /pseudo=""
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.8e-09, bitscore:
                     37.3, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 6.3e-07, bitscore: 28.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSTTPTSYRGQQAWRDLQRFLPERLRLTDGTAPEEEFWDRRGHR
                     VHLDRYPNPEARAKVVLHHGVGTDGRQMSLVLGAPLARLGFETVALDNLGYGLTQVRAG
                     TTPSYDDGVDLVVDFLAHERVRDDRPIVLYGLSAGGMLTYHVAAKAPRGTLAGIVGMTF
                     LDRRLQQVRDETAHDRIATRLGGPMTGPLARTPTAKLKCPMSLASGMSALANDPGAMKV
                     SLKDRTSAANRVSIRFLDRCMNYAPAVEPEDFD"
     aSDomain        complement(6139..6414)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ME763_RS11685_Abhydrolase_1.1"
                     /evalue="8.70E-10"
                     /label="ME763_RS11685_Abhydrolase_1.1"
                     /locus_tag="ME763_RS11685"
                     /protein_end="151"
                     /protein_start="59"
                     /score="30.5"
                     /tool="antismash"
                     /translation="VVLHHGVGTDGRQMSLVLGAPLARLGFETVALDNLGYGLTQVRAG
                     TTPSYDDGVDLVVDFLAHERVRDDRPIVLYGLSAGGMLTYHVAAKAP"
     CDS_motif       complement(6148..6210)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ME763_RS11685_0001"
                     /evalue="5.30E-05"
                     /label="NRPS-te1"
                     /locus_tag="ME763_RS11685"
                     /protein_end="148"
                     /protein_start="127"
                     /score="15.8"
                     /tool="antismash"
                     /translation="DRPIVLYGLSAGGMLTYHVAA"
     gene            complement(6588..6830)
                     /locus_tag="ME763_RS11690"
                     /old_locus_tag="ME763_11675"
     CDS             complement(6588..6830)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS11690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ME763_11675"
                     /product="hypothetical protein"
                     /protein_id="WP_107437167.1"
                     /transl_table=11
                     /translation="MDHLAWLLTDALAEAVPGTARQAAEVLLTFTRGLEDDPRDAEAAR
                     RDLGTGVQMITRGALGRPSAPARPTSRPQPEGTPS"
     misc_feature    6782..6796
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.46"
                     /tool="antismash"
     gene            complement(7068..7295)
                     /locus_tag="ME763_RS11695"
                     /old_locus_tag="ME763_11680"
     CDS             complement(7068..7295)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123531.1"
                     /locus_tag="ME763_RS11695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11680"
                     /product="hypothetical protein"
                     /protein_id="WP_085566491.1"
                     /transl_table=11
                     /translation="MHIDWSALARVAAVSLGVTVAVVVVFTLGVLGLSRAADRRTGPAT
                     TLARAQAGLCFLACAVVVGYGIYLIVPQLH"
     gene            complement(7312..8466)
                     /locus_tag="ME763_RS11700"
                     /old_locus_tag="ME763_11685"
     CDS             complement(7312..8466)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058926.1"
                     /locus_tag="ME763_RS11700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11685"
                     /product="inorganic phosphate transporter"
                     /protein_id="WP_085566490.1"
                     /transl_table=11
                     /translation="MDHITLLVAVVIVTALAFDFTNGFHDTANAMATSIATGALRPRIA
                     VLISGVLNIAGAFLSTEVARTISGGIVDDALVTPAMIFAGLVGAILWNLATWLAGLPSS
                     SSHALFGGLIGAVWVGAGSKGVHFEQVLDKVLLPAVVSPVVAGVAACAATYLAYLLSAR
                     ARQDRVTKGFRLGQIASASLVSLAHGTNDAQKTMGVITLTLISAGALGHDAGPPVWVIG
                     SAGLAIGLGTYLGGWRIIRTMGKGLTEIQSPQGFAAETASTAVILTSAHLGFALSTTQV
                     ASGSILGAGLGRRLAEVRWGVAGRMALAWLITLPFAALVGGLAASVVKHGGNIGTVVVA
                     LVALALALGVVVISRRNPVHADNVNDHHEVTLRSQTPTDIGSAV"
     gene            8608..9006
                     /locus_tag="ME763_RS11705"
                     /old_locus_tag="ME763_11690"
     CDS             8608..9006
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009718027.1"
                     /locus_tag="ME763_RS11705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11690"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_172427631.1"
                     /transl_table=11
                     /translation="MSLEDLRRLRRVRDRMDREYAEPLDMSELARGALMSPGHFQRSFR
                     KAFGETPYSYLMTRRIERAKALLRRGDLTVTEVCLAVGCTSLGSFSSRFTELVGRTPSA
                     YRAASHEPAAVIPSCVARTFTRPRRRPC"
     misc_feature    complement(9066..9079)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.25"
                     /tool="antismash"
     gene            9069..9485
                     /locus_tag="ME763_RS11710"
                     /old_locus_tag="ME763_11695"
     CDS             9069..9485
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674926.1"
                     /locus_tag="ME763_RS11710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11695"
                     /product="VOC family protein"
                     /protein_id="WP_037660218.1"
                     /transl_table=11
                     /translation="MNVRLAQCFIAVDDHDKALAFYRDILGLEVRNDVGFEGMRWVTVG
                     SPHQPDVEIVLEPPGANPDASPADRQAMAELLAKGMLRGVILATDDCDALWERLRESGA
                     DVLQEPTDQPWGVRDCAFRDPAGNLLRCFQRPAA"
     gene            complement(9509..9841)
                     /locus_tag="ME763_RS11715"
                     /old_locus_tag="ME763_11700"
     CDS             complement(9509..9841)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674925.1"
                     /locus_tag="ME763_RS11715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11700"
                     /product="DUF952 domain-containing protein"
                     /protein_id="WP_085566488.1"
                     /transl_table=11
                     /translation="MPKPSRIVHITERSLWEAARERGTYEVSTRGRTLDRVGFIHFSTR
                     EQLPSVAAFVYGGYDGPDELVVLVVDPALLDAPLTYEPVKPGGEEFPHLYGPLPVNAVV
                     DVEPWG"
     gene            complement(10001..11137)
                     /locus_tag="ME763_RS11720"
                     /old_locus_tag="ME763_11705"
     CDS             complement(10001..11137)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674923.1"
                     /locus_tag="ME763_RS11720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11705"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_085566487.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5.4e-59, bitscore:
                     198.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAESMTETEQRPSGVPYPGTPEGRRGTGDPGPAPHDGQEAPELLE
                     RSRALVDPAMRAAVESLPGSMRRIARYHFGWEHVDGSPAAGHAGKAIRPALVLAAAAAL
                     GGPAARAAAVPAAAAVELVHNFTLLHDDVMDRDPTRRHRPTAWTVFGDADAILAGDALQ
                     ALALRLLVEDPHPAAALAAARLADCVMELCAGQHTDTDLEHRAPDEVTLDEVLAMAEAK
                     TGALLGCACALGALYAGAGPEEVAALDGFGRQAGLAFQLIDDVIGIWGEPLRTGKPAGA
                     DLAARKKSLPVVAALVSGTPAAAELAALYGKPYITGDSEGIARTALAVERAGGRDWAQT
                     EAADRMARAMQELARAIPDPEAAGGLLALAEFVTRRSS"
     misc_feature    11191..11206
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     misc_feature    11191..11207
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.91"
                     /tool="antismash"
     gene            complement(11250..12656)
                     /locus_tag="ME763_RS11725"
                     /old_locus_tag="ME763_11710"
     CDS             complement(11250..12656)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="ME763_RS11725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11710"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_085566486.1"
                     /transl_table=11
                     /translation="MSVGEELRTDQGKPQQSLGTAAARNLATTTKSVPQMQEISSRWLL
                     RTLPWVDVQGGTYRVNRRLTYAVGDGRITFVKTGGQVEVIPAELGELPALRSYEDEEVL
                     AELARRCRQRDFAPGEVIADFGNRNDGVHLLAHGRVEKIGTGPYGDDSVLGVLADGSYF
                     GDQALVDPDAIWEYTVRADTASTVLILSRQDFEQIAERSQSLRDHLAQLRSIPEQRTNK
                     YGEKAVDLAAGHSGEADIPHTFVDYEARPREYELSIAQTVLRVHSRVADLYNQPMNQTE
                     QQLRLTVEALKERQEHELINNPEFGLLSNCEYDQRIQPHDGAPSPDDMDELLSRRRGTK
                     LFLAHPRAIAAFGRELNKRGLVPETIDMGGNRIPTWRGVPLFPCGKIPISEARTTSIIA
                     MRTGEDEQGVIGLRQSGLPDEIEPSLSVRFMGINEQAIIKYLVTAYYSAAVLVPDALGV
                     LENVEIGRWR"
     misc_feature    complement(12794..12809)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.5"
                     /tool="antismash"
     misc_feature    complement(12846..12858)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            12860..13783
                     /locus_tag="ME763_RS11730"
                     /old_locus_tag="ME763_11715"
     CDS             12860..13783
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674918.1"
                     /locus_tag="ME763_RS11730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11715"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_085568735.1"
                     /sec_met_domain="PALP (E-value: 4.8e-19, bitscore: 67.6,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSDPLAPRLPSPLRELRDERFDRRGIRLVLKRDDLIHPELIGN
                     KWRKLVPNIAAADGRPLVTFGGAYSNHLRATAAAGRLLGLATTGVVRGQELADRPLNPS
                     LARCAADGMRLRFVDRSTYRRKAEPETLAAILHAAGAEEAYVVPEGGSNAAAVRGCTAL
                     GAELRGHADAVAVACGTGGTLAGLAAGLAKGQRALGVPVLRGGFLTADVEALQERAFGG
                     RTGDWSLDDRFHFGGYARTTPELDAFAEDFEQRHGLPVERLYVAKLLYGLVALAEEGAF
                     PRGTTLAAVVTGRPFPEPQRPGALAT"
     gene            complement(13817..15412)
                     /locus_tag="ME763_RS11735"
                     /old_locus_tag="ME763_11720"
     CDS             complement(13817..15412)
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072182.1"
                     /locus_tag="ME763_RS11735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11720"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_085566485.1"
                     /transl_table=11
                     /translation="MDVMPLLLLVAGSAAVAGIARRTPVPAPLLLVAVGLVVSYAPGVP
                     DYTLEPDVVLPLVLPPLLYKEGTESSYLDLRAQMRPVGLLSVGYVLFATFVVGWAAYLV
                     VPGLPLPAALVLGAVVAPTDAVAAAAIARRVGLPSRITTILQGESLLNDATAITAYKVA
                     LAAAVGAGSTWAGGIEEFLRAAVGGVLVGLVLMVPIHWLRTRLTEALLQNTLSLLIPFV
                     AYGVAEQLHASGVLAVVVVAVYLGHRAWEVDFATRLQEEAVWKMVAFVLESAVFALIGL
                     QLPPILKGLAAYHGADAAWYAIAVFLVVVAARFVWTFPATFLPRVLSRRIREREEDPTW
                     RAPVVVSWAAMRGVVSLAIAFSIPETIRGGAPFPQRNLILFLTFTTVIGTLVVQGLTLA
                     PLIRLMKFPGRDRQAETLAEANAQAQASLAAERRLEELLADERNALPPPLADRLHDVLE
                     RRRNAVWERLGQANPVTGESVDDTYRRLSRAMISAEREVFVRLRDHRYIDDEMLRALLR
                     HLDLEEAAAYREAA"
     gene            15474..15734
                     /locus_tag="ME763_RS11740"
                     /old_locus_tag="ME763_11725"
     CDS             15474..15734
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571357.1"
                     /locus_tag="ME763_RS11740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11725"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_085566484.1"
                     /transl_table=11
                     /translation="MKQCTHADALPRPEPEPRSATCPECLADGTHPVQLRLCLTCGHVG
                     CCDSSPGRHATGHHEQTGHPVMRTFEPGEDWRWCFVDHVLV"
     misc_feature    complement(15787..15797)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    complement(15912..15925)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.16"
                     /tool="antismash"
     gene            16056..16472
                     /locus_tag="ME763_RS11745"
                     /old_locus_tag="ME763_11730"
     CDS             16056..16472
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="ME763_RS11745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11730"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_009190566.1"
                     /transl_table=11
                     /translation="MSQIAGEPAANQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLD
                     EIEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGHAPSRDTFAWT
                     VLSALAGKVSSAVDEDKTVSISLYKQRGAGPGPA"
     gene            16493..17596
                     /locus_tag="ME763_RS11750"
                     /old_locus_tag="ME763_11735"
     CDS             16493..17596
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136656.1"
                     /locus_tag="ME763_RS11750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11735"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_172427630.1"
                     /transl_table=11
                     /translation="MRDEERGTRELPTGDGGAPWSSAAETSGENPRDGSRRMADGIDGI
                     PEQARPHPEDHSAGPGGAGAGPDTSPEARGGAAPAGRAGARARGRATGGTMSEHERYAD
                     DGALSAEAAPHDPHDRSGARAMFVELRGLDTGSTEYAELRNQLVRMHLPLVEHLARRFR
                     NRGEPLDDLTQVATIGLIKSVDRFDPERGVEFSTYATPTVVGEIKRHFRDKGWAVRVPR
                     RLQELRLALTTATAELSQLHGRSPTVHELAEKLAISEEEVLEGLESANAYSTLSLDVPD
                     TDDESPAVADTLGAEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQIAQE
                     VGISQMHVSRLLARTLAQLREKLLVEE"
     gene            complement(17606..18049)
                     /locus_tag="ME763_RS11755"
                     /old_locus_tag="ME763_11740"
     CDS             complement(17606..18049)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006134763.1"
                     /locus_tag="ME763_RS11755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11740"
                     /product="hypothetical protein"
                     /protein_id="WP_085568734.1"
                     /transl_table=11
                     /translation="MSSEQTSVPDTAEADGTRPRRLTYAAMLAGLEGVALFVGGLWVLV
                     LGIAGAPDDRQQAVTLGITLAVLALLPLLAARGLLLRRGWSRGPAVITQLMALPVGLNM
                     LKSGGLAVPVGIVLAVVAVTALVLLVNRETTQALNIKGPGRAE"
     gene            18196..19164
                     /locus_tag="ME763_RS11760"
                     /old_locus_tag="ME763_11745"
     CDS             18196..19164
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006134762.1"
                     /locus_tag="ME763_RS11760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11745"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_085566483.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARRRDVLIHALASEMKLEAVTTEYRGHARD
                     LGRQAAESDDIDMVVALGGDGTVNEVVNGLLHAGPDLDRLPGLAVVPGGSTNVFARALG
                     LPNDPVEATGALLDALREKRERVVGLGLAAGTPGTEDEGVPARWFTFNAGLGFDAGVVG
                     RVEQQRELGKKSTHALYVRQVIRQFLGEANRRHGLITLERPGEDPIEDLVVAIVSNTSP
                     WTYLGNRPMYTSPKASFDTGIDVLGLSRLSTAAVARYGTQLLTSSPERGPHGRHAFPLH
                     DLDRFTLHSKAPLPLQMDGDHLGLRRSVTFTGVRRALRVIV"
     misc_feature    complement(19254..19263)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    complement(19426..19441)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    19429..19440
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            19485..19742
                     /locus_tag="ME763_RS11765"
                     /old_locus_tag="ME763_11750"
     CDS             19485..19742
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="ME763_RS11765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_11750"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_003992873.1"
                     /transl_table=11
                     /translation="MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVIEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQASA"
     misc_feature    complement(19961..19976)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.6"
                     /tool="antismash"
ORIGIN
        1 aagtaggccc ggcgggccgt ctccaccgtg tcgcgggtgc tggtggggag tatgaagtag
       61 gccaccgcga tgccgatcgc cgcgccgagg gcggtttcct ccaggcggag cagcaggagg
      121 ccggcggaga actcgtgcag gacgctgtag agctgggaca ccatgatggt gacgaagaag
      181 atcatgcagg cgtagctgac gttcaccaga tagaagccca gggacatgct ggtcacgatc
      241 accaccagca cccacgccgt gtgcccggcg gtgagatgcg cgaggccgat gcccgcgccc
      301 aggccgacga gggtgccgac cacccggttg accgccttga tggaggtctc ggagcgggtc
      361 gcggtaccgg cgaaggcgat gaacgcggcc agcaccgccc agtagtagcg ggcctgcgac
      421 agctcccggc ccgcgaggat cgcgaggctg ccggcgaccg cgacctggat cgcctgccgg
      481 gtcgtcagcg tcagccggct cagcgggttc cagtggctgc cgcgcgccgc gacgtccgag
      541 gccaccgccg cggaaccggg cagattgccc tgggccaggg tgacgacggg gtcgtacgcc
      601 tcgtcggtga tgtcgtcgta cggcggcggg gcggtggcgg tgcccgccag ggtgacgtac
      661 tcgacggccg cggccgccag atggtgggcg ggccagcggc cggtgcccgg tgccgccgta
      721 cccgtacggg gttccagcag ggggcgggcc acgtactcca ccgcgccgta ctcccggcgg
      781 cccagatggc cggcgatacg ggcggccgcg gggagcagtt ccccgccgtc ctcggccagc
      841 gtctcggccg ccgcggccag cgcgtcgatc gcgagatgcg cctccagcag ccggcgccgc
      901 agcgcgggtc cggaccagcc cgcgggcagc gcgccgggct ccgccgacca gccctcgatc
      961 atcaacgcgg cctcggacag gcgcagttgg cgggcgtgca gccggcggcg cagccgggcg
     1021 tggcggcgtg ggtcggccgc cagcagttcg gcactggcgc gggccaccgc acgggcccgc
     1081 gcgccgaacg cctcgcgcac ccggcgcagg gtgcggcgcg gattggtgcg cagcacggtc
     1141 agcgacagca gcagcaccca gcccgtcgcg acaccgaccg ccgacagcag ggcgggcagc
     1201 atggacagct tcgcgccgag gaacgcggcg aagaagtagc ccatccagat catgaagccg
     1261 tagaagaaga aggccatgcc gaagcggcgt acgaagaccg ccacgaacat cacggcgacg
     1321 aagacgcaca gcatcagatc cgtacggccg gccaccgcga cgcccgcgag catcccgatg
     1381 ccgatggccg gcgggaagaa gacggcggtg cgcaccttcg gccagacacc ggtgccggac
     1441 agggccatcg agcccatcat cgccatgacg gtgccgagca gcatcgcgat cagggtgccc
     1501 tgggggcccg cgtgggtcgc ggtggcgtac aggtactcga tgcccagcgt ggtggccatc
     1561 gccagcgcgg ccgacagggc catgcgcagc cggttcagcc cggggtccga gccgaccacc
     1621 ctgtcccgta ttccgcgcag cgcggccact cctcggtcca cccgtgtcca ctccccccag
     1681 tgatccggaa ccctcaggtc cggacccttg caatcccggt acgataccgg taactatcgg
     1741 tatcataccg ataaccgctg atgcgatact ggtatcagtc gatggtgaga cggcggtaca
     1801 ggatgaccgg agtggacccg gcgctcgatg tgatcgagcg gcagacggcc gtgctgatgc
     1861 gcaacttcga gctgctgcac cggcgtaccg atgtccacga ccgtctcgac cgggcgcagt
     1921 atctgctgct gcgcaccctc agcgacggcg gcccgatgac catcaccacc ctcgcctgca
     1981 ccctcggcct cgacccctcc accgcgggcc ggcaggtctc cgcgctcacc gccgccggcc
     2041 tggtcgagcg caccgccgac cccgccgacc ggcgccgctg ggtggtcacg cccaccgcgg
     2101 acgggctgcg cgagatgcgg gtcgtacggg accggcgcac cgagagccac gccgaactgc
     2161 tgggcgactg ggacccggag gatctgcgga cgctgggcac catgctggac cggtacaacc
     2221 gggcggtcgc cgcgcgctac ctcctcacac cgccaacgga ggcagccacg gaggcctcca
     2281 cagggacggt ggcccgcgcg agaacggcgg atcccgccga gaccccggcc atcacgtcgc
     2341 ccgcctgacc caccaaaacc ccggccacca cgtcgaccga ctgacccacc aaaaccccgg
     2401 ccaccgcttc atccagccgt cccgccgagg ccccggccac cgcttcgccc ggctgacccg
     2461 agcctctgac ggcacccctg aggggcgccc ctgacggcac ccctcacggc cggaaccccg
     2521 ccacgatccg gttgatcacc gccgccgccg tctccagctc ctccggcgag aactccccca
     2581 gcgcctcacc gagccaccgc ttccccgtgg cctcggcgcg cgcgaccgcc tcccggccct
     2641 ccccggtggc ccgcgcccgg cgcgcccgtt ggtcccccgg ctcccgggtg gtggcgacca
     2701 ggccgccgtc ctcaagccgg cgcacctcgc gggtgacatg cggggcgttc accatcaggg
     2761 ccgcggcgag ctcgcccatc cgcaggggtt ccggcgacgc cgcgagcacc cgcagcaccg
     2821 cgagggacgc ccggtccacc gagactccgg cctcccggcg cagcctgctg tgcgcgcggt
     2881 tgccggtcat ggtgtacgcg agcgccgaga gcgcggtgta gaggccgtcc agggccgccc
     2941 gcccctcggg gtccatctcg ggttccatgg ggtccacccg tcggtccatc caccgatcat
     3001 gtcgtacggt cccggccccc gtcgcccctg gctgaaactt gccccctaca cctattccgc
     3061 ctcccccacc cgccggagta acatgaaagt aacttactta cttttgttaa gtaaccgagg
     3121 aggtccacga caatgcccga gacccccacc gcgccgccgg tcccggcccc ggccccggcc
     3181 gcgccccccg cctactccac ccaccgcgcc cccggctgcc ccttcgaccc cccgcccgag
     3241 cgccaccggc tgctcaccga gggcccgctg gcccgtatct ccctgtggga cggcaacacc
     3301 gcctggctgg tgacccggca cgccgaccag gtcgcgctgc tgcgggacga gcggatcagc
     3361 gcggacaacc ggctgccgaa cttcccgagc gtgagcgccg gaagccaggc cacccgcgcc
     3421 cacaaccgca cgttcatctc gatggacgag ccggagcaca acgagcaacg gcggcgtttc
     3481 accgccgact tcaccgtcaa gcggatcaac gagctgcggc cccggatcga ggcgatcgtc
     3541 accgagctgc tggacgcgat ggagcaggcc ggaccgccgg ccgacctggt gcgggacttc
     3601 gcgctgccgc tgccctcgct ggtgatctgc gaactgctcg gtgtccccta caccgaccac
     3661 gccttcttcc agcgggtcag cgcggtgatg atcgacaccc gcagcacccc cgaggtcgcg
     3721 ctcgccgcct cccaggaact ggtggactac ctcggcgacc tggtggccgc caaggagaag
     3781 gaccccggcg acgatctgct cagccggatg gccgtccagt acctgcgcac cgggatcagc
     3841 acccgtgacg aatgcgccaa gcaggcccgg ctgctgctgg tggccgggca cgagacgacg
     3901 gccaacatga tcgcgctcgg cgtctgcgcg ctgctccagc accccgagca gctcgcggcc
     3961 gtgcgcgacg gcgagccgcg ccgggtggtc aacgccgtcg aggagctgct gcgctacctg
     4021 accatcgtgc atctggggcg gcgccgggtc gcggtcgcgg acgtggcggt cggcgggcag
     4081 gtgatccgcg cgggcgaggg cgtcgtcttc gccaccgatc tcgccaaccg cgaccccgag
     4141 gtcttcgagg accccgaccg gctggacatc gaccgggccg cccgccggca catcgccttc
     4201 ggcaccggcc cccaccagtg cctcggccag aacctcgccc ggatggaact ccaggtcgcc
     4261 taccccgcgt tgctgcgccg gttcccgggc ctgcgcctgg agcggccgct gacacagatc
     4321 ccgttccggg aggacatggc cgtctacggg gtgtacgagc tgcccgtggc ctggtgagcg
     4381 cgcggacgct cccctgacag gagacctggc ccaagatttc atcaagtaac ttggcaaagt
     4441 tacttgatga aatctacggt gagggcgtga ccaccggctc cactcccgct cccccgacgc
     4501 ccccctccga caccgcgcag cggctcaacc aggcgatgaa gcgcctgcgg gcgcggctgc
     4561 gcgcggagtc ggggcagcac gcgaccgggc tgaccgccac ccaactcgcc gtcctggccg
     4621 aggtggtgcg cgagggcccg gtcacggcgg cgcggctcgc cgcgctggag cacgtcacgc
     4681 cccaggccat cgcccagagt ctcgcggtgc tgaaggccgc cgggctggtg cacggcgcgc
     4741 ccgacccgcg ggacggccgc cgcaagctga tcagcgccga cccctcggcc ggcgcgctga
     4801 tcgagcggct gctcgcgggg cgcgcgacgt tcctggcccg ggcgatcacg caggtcgtgc
     4861 ggccggagga gcgcgacgac ctggaaaagg ccgtcgagct gctggagcgt cttgccgggg
     4921 ccgagatcca cccgcacatc ccatgagatc cgcgaggaga accacccaat gaccagcccc
     4981 gccgccctgc ccgtcatcga ccccgcgcgc accgccctgc tggcgatgga cctccagggc
     5041 gggatcctgc cgctcgtccc ggacccggac gccctggtcg agcgggtcaa gggtgccatc
     5101 gccgacgtcc gcgccgccgg tggcgccatc ggctatgtcc gggtcgcctt caccgaggac
     5161 gactgggccg cgatcccgga gaccaacaag tccttcagcc cgctggccgc ggccaagcgc
     5221 aaccaccacg aggacccgga cacccaggtc gacgcgcgga tcgcgcccga ggccggcgac
     5281 atcgtcgtac gcaaggtccg catcggcgcg gcctccacga ccgatctgta cgagcggctg
     5341 cgcgagcgcg gcatcgacac gctgatcctc tccggcatca gcaccagcgg tgtcgtgctg
     5401 tccacgctga ccgacgccgc cgaccgcgac taccgggtca tcgtgctgtc cgacggtgtc
     5461 gccgaccggg accaggaggt ccaccgggtg ctgctggaga aggtgttccc gatgcggtcg
     5521 tacgtcatcg acatcgcgga gctgcgcgaa ctgctgggcg tcgcctgatc gttcgtacga
     5581 cggtcccggc ccgcgcccgt gcctgcgcct gcgctcaagt gggcgctcag gcggcgcact
     5641 tcgtgacgaa gtccgcgatg gcgtcccgca tctgccgcag gccgggctcc tccagggggt
     5701 agtgccccgc gttgtcgagc atgaggtgtc gaccgggacc tttgtgatcc gggacaggac
     5761 cggcacgctg aggtggtgcg gggtccagcg gtcctcggcg ggctgggtca gcaggacggg
     5821 gcaggcgtcg aagtcctcgg gttcgaccgc gggggcgtag ttcatgcagc ggtccaggaa
     5881 gcggatgctg acccggttcg cggccgaggt gcggtccttg agggacacct tcatcgcgcc
     5941 ggggtcgttg gcgagcgccg acatcccgct cgccaggctc atcgggcact tcagcttggc
     6001 ggtcggggtc ctggccagcg gtcccgtcat cgggccgccg aggcgggtgg cgatccggtc
     6061 gtgcgcggtc tcgtcgcgga cctgctggag gcgccggtcg aggaaggtca tgccgacgat
     6121 gccggccagg gtgccgcgcg gcgccttggc ggccacgtgg tacgtgagca tgccgcccgc
     6181 gctgagcccg tacaggacga tcgggcggtc gtcgcggaca cgctcgtggg cgaggaagtc
     6241 cacgaccaga tcgaccccgt cgtcgtacga cggtgtcgtg cccgccctga cctgggtgag
     6301 gccgtagccg aggttgtcga gggcgacggt ctcgaagccg agccgcgcga gcggggcgcc
     6361 gaggacgagg gacatctggc ggccgtcggt gcccacgccg tggtgcagca cgaccttggc
     6421 gcgcgcctcg gggttcgggt accggtcgag gtggacgcgg tgtccgcgcc ggtcccagaa
     6481 ctcctcctcg ggagcggtcc cgtcggtcag gcgcagccgc tcgggcagaa agcgctggag
     6541 gtcgcgccat gcctgctggc cgcggtagga ggtgggggtg gtggagctca tgagggggtg
     6601 ccttccggct ggggcctgct ggtgggtcgg gcgggggctg aggggcggcc cagtgcccct
     6661 cgggtgatca tctgcacgcc ggtgccgagg tcccggcggg cggcctcggc atcgcgcggg
     6721 tcgtcctcca ggccccgggt gaaggtgagc agcacctcgg ccgcctgccg ggcggtgccg
     6781 gggacggctt cggccagggc gtcggtgagc agccacgcga ggtggtccat gcaggcgccg
     6841 accggctcgg ggtgtgggcg gaggccgcgg ccagcagctc gtaggcgtgc gtggggctgt
     6901 cctgccggag ccggatggac acctccagct tcacggtgag cacatcgagc accttctcct
     6961 cggccgtacc cgcctccgca acggcccgct cggccgccgc ggcggcccgt tccaggccgg
     7021 tgcggacgat cgtggcgaac acctcgtcct gggcggacgg aaccctgtca gtgcagctgg
     7081 ggcacgatca ggtagatgcc gtagcccacc accacggcgc aggccaggaa gcacagtccc
     7141 gcctgggcgc gggccagggt ggtggcgggg cccgtgcggc ggtcggcggc gcgggagagg
     7201 ccgaggacgc cgagggtgaa gacgacgacc acggcgacgg tgacgccgag gctgaccgcg
     7261 gcgacccggg cgagggcgga ccagtcgatg tgcatggcgg actcccggga ttcagacggc
     7321 cgagccgatg tcggtggggg tctgggagcg gagggtgacc tcgtggtggt cgttgacgtt
     7381 gtcggcgtgc accgggttgc ggcgggagat gacgacgacg cccagggcga gcgccagcgc
     7441 caccagggcg acgacgaccg tgccgatgtt gccgccgtgt ttgaccacgc tcgccgcgag
     7501 gccgccgacc agcgcggcga acggcagggt gatcagccag gccagcgcca tccgcccggc
     7561 cacaccccag cggacctccg cgagccggcg gccgaggccc gcgccgagga tgctgccgga
     7621 ggcgacctgg gtggtggaca gggcgaagcc gaggtgggcg gaggtgagga tcaccgcggt
     7681 ggaggccgtc tcggcggcga agccctgcgg cgactggatc tccgtcaggc ccttgcccat
     7741 ggtgcggatg atccgccagc cgcccagata ggtgccgagg ccgatcgcga gaccggcgga
     7801 gccgatcacc cagaccggcg gcccggcgtc atgaccgagc gcgcccgcgg agatcagggt
     7861 cagcgtgatc acgcccatgg tcttctgcgc gtcgttggtg ccgtgcgcga gggagaccag
     7921 ggaagcggag gcgatctggc cgagccggaa gcccttggtc acccggtcct ggcgggcgcg
     7981 ggcggagagc agataggcga gataggtggc ggcacaggcg gccaccccgg ccaccaccgg
     8041 ggagacgacg gcgggcagca gcaccttgtc gagcacctgc tcgaagtgca cgcccttgga
     8101 ccccgcgccg acccagaccg cgccgatcag cccgccgaac agggcgtgcg aggaactgga
     8161 gggcagcccg gcgagccagg tcgccaggtt ccacaggatc gccccgacca gcccggcgaa
     8221 gatcatcgcg ggggtgacca gggcgtcgtc cacgatgccc ccggagatcg tccgggccac
     8281 ctcggtggac aggaacgcgc ccgcgatatt gagaacaccg ctgatcagga ccgcgattct
     8341 gggccggagc gcgccggtgg cgatggaggt ggccatcgcg ttcgcggtgt catggaaccc
     8401 gttcgtgaag tcgaacgcca gcgccgtcac gatgacgacc gccacgagca acgtgatgtg
     8461 gtccatgact ccagccaacc aagacccggc cgattccgcg cgaactggga gcgaaagccc
     8521 gggagtgccc aggaggagac ggggtgggca gggcggcccg tgatgatccc gggtccggtg
     8581 tcggtgggct gtgccaagct ggtgggcgtg agtctggagg atctgcggcg gctgcggcgg
     8641 gtacgggacc ggatggaccg ggagtacgcc gagccgctcg acatgagcga gctggcgcgc
     8701 ggcgccctga tgtccccggg ccatttccag cgcagcttcc gcaaggcgtt cggggagacg
     8761 ccgtacagct atctcatgac ccgccgtatc gagcgggcca aggcgctgct gcgccggggc
     8821 gacctcacgg tcaccgaggt gtgcctggcc gtggggtgta cgtccctggg gtccttcagc
     8881 tcccgtttca ccgaactggt cggccggacc ccgagcgcct atcgtgccgc ctcgcacgag
     8941 ccggccgcgg tgatcccctc ctgcgtggcc cgcaccttca cccggccccg ccgccgcccc
     9001 tgctgagctc cccgggccgt ccccggaagc cgcgcgcgcc ggcctcccga ccggcttagc
     9061 gtgaacgcat gaacgtacga ctcgcacagt gcttcatcgc cgtggacgac catgacaagg
     9121 cccttgcctt ctaccgcgac atcctcggtc ttgaggtccg caacgacgtg ggcttcgagg
     9181 ggatgcgatg ggtgaccgtc gggtcgccgc accagccgga cgtggagatc gtgctggagc
     9241 cgccgggcgc caacccggac gcctcccccg ccgaccggca ggcgatggcc gaactgctcg
     9301 ccaagggcat gctgcgcggg gtcatcctgg ccaccgacga ctgcgacgcg ctgtgggagc
     9361 ggctgcgcga gtccggcgcc gacgtcctcc aggagccgac cgaccagccg tggggcgtcc
     9421 gcgactgcgc cttccgcgac ccggcgggca atctgctgcg ctgcttccag cgcccggcag
     9481 cctgaactcc cctggcgcac gcggtacttc acccccaggg ttccacgtcc accacggcgt
     9541 tcaccggcaa cggtccgtag aggtgcggga attcctcgcc gcccggcttc accggctcgt
     9601 acgtcagagg cgcgtcgagc aacgccggat ccaccaccag gaccaccagt tcgtccgggc
     9661 cgtcgtaccc gccgtacacg aacgcggcga cggacgggag ctgctcgcgg gtggagaagt
     9721 ggatgaagcc cacccggtcg agggtgcggc cccgggtcga cacctcgtag gtgccgcgct
     9781 cgcgggccgc ctcccacagg gagcgctcgg tgatgtggac gatgcgggac ggtttcggca
     9841 tggcttcacg gtagacggcg ggccccgtgg actgtgggga tccacgggac ccggccgacc
     9901 ggagcccccg gggcaccgtg cggggtcagg agccgcacgg gcccggggac tccgggtcct
     9961 cggggccgcc ggacggaccg gcggcgcgga ccgcggcgct tcagctgctg cgccgggtca
    10021 cgaactcggc gagggcgagc agcccgcccg ccgcctcggg gtccgggatc gcccgggcca
    10081 gttcctgcat cgcgcgggcc atccggtcgg ccgcctccgt ctgcgcccag tcccggccgc
    10141 cggcccgctc cacggccagc gcggtccgcg ctatgccctc gctgtccccg gtgatgtacg
    10201 gctttccgta cagcgcggcg agttcggccg ccgccggggt gccggagacg agtgccgcca
    10261 ccaccggcag ggacttcttg cgggccgcga gatcggcacc ggccggcttg ccggtccgca
    10321 gcggctctcc ccatatgccg atgacgtcgt cgatcagctg gaaggcgagc cccgcctgac
    10381 ggccgaagcc gtccagcgcg gccacctcct cgggccccgc gcccgcgtac agcgcgccga
    10441 gggcgcaggc gcagcccagc agcgcccctg tcttcgcctc ggccatggcg agcacctcgt
    10501 ccagcgtgac ctcatccggg gcgcggtgct ccaggtcggt gtccgtgtgc tggccggcgc
    10561 acagctccat cacgcagtcc gcgagccggg cggcggccag ggccgcggcc gggtgcgggt
    10621 cctcgaccag cagacgcagc gcgagcgcct ggagcgcgtc cccggcgagg atcgcgtcgg
    10681 catccccgaa cacggtccag gccgtgggcc ggtgcctgcg ggtggggtcc cggtccatca
    10741 catcgtcgtg cagcagggtg aagttgtgga ccagctccac cgccgccgcg gccggtacgg
    10801 cggccgcccg ggccgccggg ccgccgagcg cggcggccgc ggcgagcacc agggccggcc
    10861 ggatcgcctt gcccgcatgg cccgcggccg ggctgccgtc cacgtgctcc cagccgaagt
    10921 ggtagcgcgc gatccggcgc atggaaccgg gcagcgactc gacggcggcg cgcatcgccg
    10981 ggtcgaccag ggcccggctc cgctccagca gctccggcgc ctcctgcccg tcgtgcgggg
    11041 cggggcccgg gtcaccggtc ccccgccgtc cctccggtgt gccggggtac ggcacaccgg
    11101 agggacgttg ttcggtctcc gtcatggact cggccatgtc tccccctcgc caggtccgcg
    11161 ggcatcggcg gatcctgccc ggccggacgc gtaccccgag ggtgtacccg tccgggcgtt
    11221 cagggacacg gccacgacgt gcggaaacgt cacctccacc ggccgatctc gacgttctcc
    11281 agcacaccga gcgcgtcggg caccaggacg gcggccgagt agtaggccgt gaccaggtac
    11341 ttgatgatcg cctgctcgtt gatccccatg aagcggacgg acaggctcgg ctcgatctcg
    11401 tccgggagac cggactgccg cagaccgatg acgccctgtt cgtcctcgcc ggtgcgcatc
    11461 gcgatgatcg aggtggtgcg cgcctcgctg atcgggatct tgccgcaggg gaagaggggc
    11521 accccgcgcc aggtggggat gcggttgccg cccatgtcga tggtctccgg caccagaccc
    11581 cgcttgttca gctcgcggcc gaacgcggcg atcgcgcgcg ggtgggcgag gaacagcttg
    11641 gtcccgcggc ggcggctgag cagttcgtcc atgtcgtccg ggctcggggc gccgtcgtgc
    11701 ggctggatcc gctggtcgta ctcgcagttg ctgagcagac cgaactccgg gttgttgatc
    11761 agttcgtgct cctggcgctc cttcagcgcc tcgaccgtga gccgcagctg ctgctcggtc
    11821 tggttcatcg gctggttgta gaggtcggcc acccgggagt ggacgcgcag cacggtctgg
    11881 gcgatgctca gttcgtactc gcggggccgg gcctcgtagt cgacgaaggt gtgcgggatg
    11941 tcggcctcgc cggagtggcc cgcggccagg tcgaccgcct tctcgccgta cttgttggtg
    12001 cgctgctccg ggatcgagcg cagctgggcc agatggtcgc gcagggactg ggagcgctcg
    12061 gcgatctgct cgaagtcctg gcggctgagg atcagcacgg tgctggcggt gtccgcgcgg
    12121 accgtgtact cccagatggc gtccgggtcg accagcgcct ggtcgccgaa gtaggagccg
    12181 tcggcgagga cgccgaggac cgagtcgtcg ccgtaggggc cggtgccgat cttctcgacg
    12241 cggccgtggg cgagcagatg caccccgtca ttgcggttgc cgaagtcggc gatgacctcg
    12301 ccgggggcga agtcgcgctg gcggcagcgc cgggccagct cggccagtac ctcttcgtcc
    12361 tcgtacgacc gcagggccgg gagttcgccg agttcggccg ggatgacctc gacctggccc
    12421 ccggtcttga cgaaggtgat ccggccgtcg ccgacggcgt acgtcagccg gcggttgacc
    12481 cggtacgtgc cgccctggac gtccacccag gggagcgtgc gcagcagcca gcgggagctg
    12541 atctcctgca tctgcggaac ggacttggtg gtggtggcca ggttccgcgc tgccgcggtc
    12601 ccgagggact gctgcggctt gccctgatcc gtgcggagct cttcgcctac cgacatgtgg
    12661 aaatgccctc ccatgtaatg caccggtcgc aacgggccgg tctcgcatcg agcgtcccat
    12721 cacgcacggt tgccacgcca ttacccgaaa gagggggaat ggatcatcgg actagtgggc
    12781 agaaaggagg accgtgaaaa aggggccgac ctcgccgacc tcgtggatcc gcaccccgat
    12841 cccgggcgac aatgacaccg tgaccagcag cgatcccctc gccccccgcc ttccctcgcc
    12901 ccttcgggag cttcgggacg agcggttcga ccggcgcggg atccggctgg tgctcaagcg
    12961 ggacgacctg atccacccgg agctgatcgg caacaagtgg cgcaagctcg tgccgaacat
    13021 cgccgcggcg gacgggcggc cactggtcac cttcggcggg gcctactcca accatctgcg
    13081 cgccaccgcg gccgccggac gactgctcgg gctcgccacc accggtgtgg tgcgcggtca
    13141 ggagctggcc gaccggccgc tcaacccctc cctcgctagg tgcgcggcgg acgggatgcg
    13201 gctgcggttc gtcgacagat cgacctaccg gcgcaaggcc gagccggaga cgctggcggc
    13261 gatcctgcac gcggcaggcg ccgaggaggc gtacgtcgtg ccggagggcg gcagcaacgc
    13321 ggcggcggtg cgcggctgta cggcgctcgg ggcggaactg cgcgggcacg ccgatgccgt
    13381 cgcggtcgcc tgcggcaccg gcggcacgct cgcgggactc gcggccggac tggcgaaggg
    13441 gcagcgcgcg ctcggggtgc cggtcctcag gggcggcttc ctgacggccg acgtcgaggc
    13501 attgcaggaa cgtgccttcg gcggccgtac cggcgactgg tcgctggacg accgcttcca
    13561 cttcggcggc tacgcgcgga ccacccccga actcgacgcg ttcgccgagg acttcgagca
    13621 gcggcacggg ctgcccgtgg agcgtctcta tgtcgccaag ttgctctacg ggcttgtcgc
    13681 cctcgccgag gagggcgcct tcccgcgcgg cacgacactc gcggccgtcg tcaccggccg
    13741 gccgttcccc gagccccagc ggcctggagc cctggccacc tagagtcccg gcagcgccga
    13801 gccccggccc cgggggctac gccgcctccc ggtacgcggc cgcctcctcc aggtccaggt
    13861 gccgcagcag ggcgcgcagc atctcgtcgt cgatgtagcg gtggtcgcgc agccgtacga
    13921 agacctcgcg ttcggcgctg atcatggcgc gggacagccg gcgataggtg tcgtccacgg
    13981 actcgccggt gacggggttc gcctggccga ggcgctccca gacggcgttg cggcggcgct
    14041 ccaggacgtc gtggaggcgg tcggcgagcg gcggtggcag cgcgttgcgc tcgtcggcga
    14101 ggagttcctc caggcggcgt tcggcggcca gggacgcctg tgcctgggcg ttggcctcgg
    14161 ccagggtctc ggcctggcgg tcgcggccgg ggaacttcat caggcggatc agcggggcga
    14221 gggtgaggcc ctgcacgacc agggtgccga tgaccgtggt gaaggtcagg aagaggatca
    14281 ggttgcgctg cgggaagggc gcgccgcccc ggatcgtctc cgggatggag aaggcgatgg
    14341 ccagggagac cacaccccgc atcgccgccc aggagaccac gaccggcgcc cgccaggtgg
    14401 ggtcctcctc gcgctcccgg atgcgccggg acagcacgcg cggcaggaag gtcgccggga
    14461 acgtccagac gaaccgggcg gccacgacga ccaggaagac ggcgatcgcg taccaggccg
    14521 cgtcggcccc gtgataggcc gcgaggccct tgaggatggg cggcagctgg aggccgatca
    14581 gcgcgaacac ggccgactcc agcacgaagg cgaccatctt ccacacggcc tcctcctgga
    14641 gccgggtggc gaagtcgacc tcccaggcgc ggtgcccgag gtagacggcg accacgacca
    14701 ccgcgagcac tccggaggcg tgcagctgct cggcgacccc gtaggcgacg aacgggatca
    14761 gcagcgagag ggtgttctgg agcagcgcct cggtcagacg ggtgcgcagc cagtggatcg
    14821 gcaccatgag caccaggccg acgagcacgc cgccgaccgc cgcgcgcagg aactcctcga
    14881 tgccgcccgc ccaggtggag cccgcgccga cggcggcggc gagggccacc ttgtaggcgg
    14941 tgatcgcggt ggcgtcgttc agcagcgact cgccctggag gatcgtggtg atccgggacg
    15001 gcagcccgac ccggcgggcg atcgccgcgg ccgcgaccgc gtccgtcggc gccacgaccg
    15061 cgccgagcac cagcgcggcg ggcagcggca gccccggtac gacgagatag gcggcccagc
    15121 cgacgacgaa ggtcgcgaag agcacgtacc cgacggacag cagccccacc gggcgcatct
    15181 gggcccgcag gtccaggtag gagctctcgg tgccctcctt gtagagcagc gggggcagca
    15241 ccaggggcag cacgacatcg ggttcgagcg tgtagtcggg gacgccgggc gcgtacgaca
    15301 ccaccaggcc caccgcgacc agcagcagcg gcgcgggcac cggggtgcgc cgggcgatcc
    15361 cggcgaccgc ggcactgccc gcgaccagca acagcagggg catcacgtcc atgcgtctcg
    15421 cccaccctca ttttccgcgc ggtcacccgc acacccgtcg taatctggca atcatgaaac
    15481 agtgcacgca cgccgacgcg ctgccacgtc cggaacccga gccgcgctcc gcgacctgtc
    15541 cggagtgcct ggccgacggg acgcacccgg tgcagctgcg gctctgcctg acctgtggcc
    15601 atgtcggctg ctgcgactcc tcaccgggcc ggcacgccac cgggcaccat gagcagaccg
    15661 gacatccggt gatgcggacg ttcgaaccgg gcgaggactg gcggtggtgc ttcgtggacc
    15721 acgtactcgt ctgagcggta cccgggtccg atcgttgatc atcttctcgt tcgggcactg
    15781 tgtcgtgtga cactgcatgc ggcggcgcac gcacgacggt tcgggcgtct gacgtctggg
    15841 tacgtcaacc cggcgcgcgc tcttccgatt tggggccgca caccccctag acacggagcg
    15901 tatccacagc tttactgtga gtgacgccag ggggtcgggg tcccggggac ggaaacattc
    15961 ggcgcgcgat agcgtcaccg cttgaaccac ctacgcgtta gccccggggg gcgaccctcg
    16021 gcccctgtaa agcttgtacc accatggagg tgagggtgtc ccagatcgca ggcgaacccg
    16081 cggcgaacca ggatttcgtg gaggtccggc tgccggccgc gggtgcctac ctgtcggtgc
    16141 tgcggacggc cacggccggt ctggcggccc gcttggactt caccctggac gagatcgagg
    16201 atctgcgcat cgccgtggac gaggcctgcg cgatcctgtt gcagcaggcc gtgccgggct
    16261 cggtgctcag ctgtgtcttc cggctcgtcg acgactcgct ggaagtcacc gtgtcggccc
    16321 cgaccacgga cggccatgcc ccctcgcggg acaccttcgc ctggaccgtg ctgtcggccc
    16381 tcgcggggaa ggtctcgtcc gccgtcgacg aggacaagac ggtgtccatc agcctctaca
    16441 aacagcgcgg cgcgggtccc gggccggcgt gagggagaac ggggacggtc cggtgcggga
    16501 cgaagagcgc ggcacgcgtg agctgccgac cggggacggg ggtgccccct ggtcgagtgc
    16561 ggcggagacc tccggggaga acccccgcga cggttcccgg cgcatggcgg acggcatcga
    16621 cggcatcccc gagcaggcca ggccacaccc ggaggaccac tccgcagggc caggcggtgc
    16681 gggcgcaggc cccgacacct cgcccgaggc gcgcggcggg gccgctcccg ccggccgcgc
    16741 gggggcgagg gctcggggaa gggctacggg cgggacgatg agcgagcacg agcgatacgc
    16801 ggacgacggc gcgctgagcg cggaggccgc accgcacgac ccgcacgacc gcagcggggc
    16861 ccgtgccatg ttcgtcgaac tgcgcgggct cgacacgggc agcacggagt acgcggagct
    16921 gcgcaatcag ctggtccgta tgcatctgcc gctcgtggag cacctggcgc gccggttccg
    16981 caaccgcggc gagccgctgg acgacctcac ccaggtcgcc acgatcggtc tgatcaagtc
    17041 cgtggaccgg ttcgacccgg agcggggcgt ggagttctcc acgtacgcca cgccgaccgt
    17101 ggtcggcgag atcaagcggc acttccggga caagggctgg gcggtccggg tgccgcgccg
    17161 cctccaggag ctgcggctcg cgctgaccac ggcgacggcg gagctgtccc agctgcacgg
    17221 ccgctcgccg acggtgcacg aactggcgga gaagctcgcg atctccgagg aggaggtcct
    17281 ggagggcctg gagtcggcga acgcgtactc cacgctgtcc ctggacgtcc ccgacaccga
    17341 cgacgagtcc cccgcggtcg ccgacacgct cggcgcggag gacgaggcgc tggagggggt
    17401 ggagtaccgg gagtcgctca agccgctgct ggaggatctg ccgccgcggg agaagcggat
    17461 cctgctgctg cggttcttcg ggaacatgac gcagtcccag atcgcgcagg aggtcgggat
    17521 ctcccagatg cacgtctccc ggctgctggc gcgcacgctg gcgcagctgc gggagaagct
    17581 gctggtggag gagtagggcg cctgcctact cggcgcggcc cgggcccttg atgttcaggg
    17641 cctgggtcgt ctcgcggttg acgagcagca caagagccgt gacggccacg acggcgagga
    17701 cgatcccgac cgggacggcg agaccgccgg acttgagcat gttcagcccc accggcaggg
    17761 ccatcagctg ggtgatcacg gcggggcccc ggctccagcc gcggcgcagc agcaggccgc
    17821 gggcggccag gagcgggagc agggcgagca cggcgagggt gatacccagc gtcacggcct
    17881 gctgccggtc gtcgggggcg ccggcgatgc cgagcacgag gacccagagg ccgccgacga
    17941 acaacgcgac gccttccagg ccggccagca tggcggcgta cgtcagccga cgggggcggg
    18001 tgccgtcggc ttcggccgtg tccggtacgg aggtctgctc actgctcacc tcagcagggt
    18061 agccgtcggc gggagcgggc cgggggtgga cccggtcacc ggtcccgccc acgtgtgcgg
    18121 gctcaccccc tcccctctta cccgatccct acctcggcct gggcccggta ccgccgggta
    18181 ggtacgctga cgtgcatgcg tgctctcctc gtggtcaatc cggcggcaac caccaccagc
    18241 gcacgcaggc gtgatgtgct gatccacgcg ctcgccagcg agatgaagct ggaggcggtc
    18301 accaccgagt accgcggaca cgcccgggac ctgggccggc aggccgcgga gagcgacgac
    18361 atcgacatgg tcgtggccct cggcggcgac ggcaccgtca acgaggtggt caacgggctg
    18421 ctgcacgcgg gccccgatct ggaccggctg cccggcctcg ccgtcgtgcc cggtggatcc
    18481 accaacgtct tcgcccgtgc cctcgggctg cccaacgacc ccgtcgaggc caccggcgcc
    18541 ctgctggacg cgctgcgcga gaagcgggag cgcgtggtgg gcctcggtct cgccgccggc
    18601 acccccggta ccgaggacga aggggtaccg gcccgctggt tcaccttcaa cgcgggactg
    18661 ggtttcgacg cgggcgtcgt cggccgggtc gaacagcagc gcgagctggg taagaagtcg
    18721 acgcacgcgc tctacgtacg gcaggtgatc cggcagttcc tcggcgaggc caatcgccgg
    18781 cacggcctga tcactctgga gcggcccggc gaggacccga tcgaggatct tgttgtcgcc
    18841 atagtctcga acacgtcccc ttggacgtat ctcggcaatc gccctatgta cacatcacct
    18901 aaggcttcgt tcgacacggg catcgacgta ctcggtctca gccgcctgtc gacggccgcg
    18961 gttgcccggt atggcaccca gttgctcact tcgtcccccg agcgcggacc ccatggcagg
    19021 catgcgttcc cactccatga tctggaccgc ttcaccttgc attcgaaggc tcctctgcct
    19081 ctacagatgg acggtgacca cctggggctg cgcaggagcg tgacgttcac aggcgtacgc
    19141 cgcgcactgc gtgtgattgt gtgagtggaa gaggcgaaag tcctttcact cgaacgttta
    19201 ggccaggatc caccccatgg aagtacggct gtgacccagt cgacaccgag gaatcaaaaa
    19261 aaactttccg gaaggggttg tatccgccgc tgaggtttgc gagtctctac gtggcgatcg
    19321 ggacggcccc caacaccggc ctccactgat caccggaacc cctcttcata ccaaggaccc
    19381 cgccggggaa gactcggcgt tcggcccttc acttgtcgag ggattcgtga aagcgttcac
    19441 attcacaagc aacttgcacg taataccaag gagaggtagc agccatggac tggcgtcaca
    19501 acgccgtttg ccgcgaggaa gaccccgagc tcttcttccc catcggcaac accggtcccg
    19561 cgctgctgca gatcgaggaa gccaaggccg tctgccgtcg ctgcccggtg atcgagcagt
    19621 gtctgcagtg ggcgcttgag tccggccagg actccggcgt ctggggtggc ctcagcgagg
    19681 acgagcgtcg cgcgatgaag cgccgtgccg cccgcaaccg ggcccgtcag gcctccgcct
    19741 gacacaccca ccccagctga cagcctgagc ttggcggcgc gtgcatcgag cacgcatctc
    19801 ccgcccccga gcagcagcgc gcagtatccc cccgatgccg cccagcgaac agcagcgcag
    19861 caacgagcac gagcctcgga ccaatgacgg tccggggctt tttgctttcc cggagcgcgc
    19921 ctcggagcct gccccggagc gcgtcacgcc cggcgccgcc actggttcag accaacaccc
    19981 cctcccccgg gggccgttga ctacttctgc gcgcgcaccg ggatgtccag gatcaccctg
    20041 gtcccccgct ccggcgccgg gaccatgtcg aacgtgccac ccaactcgcc ctccaccagg
    20101 gtccgtacga tctggagccc caggttgccc gagcggtgcg ggtcgaagcc ctcgggcaga
    20161 ccgaccccgt cgtcctggac ggtgacgagg agccgggcct ccttcgtgct gccgccgcgc
    20221 accgccgaga cctccaccgt gccggtctcg ccctcgcgga acccgtgctc cagggcgttc
    20281 tggagcacct cggtgagcac catcgacagc ggtgtggcca cctcggcgtc gagtatcccg
    20341 aagcgcccgc tgcgccggcc ggtcaccttg cccggcgaga tctcggcgac catcgccagc
    20401 acccggtcgg cgatgtcgtc gaactccacc cgctcgtcca ggttctggga gagcgtctcg
    20461 tgcacgatgg cgatggagcc gacccggcgc accgcctcct ccagggccgc gcgcccgcgt
    20521 tcggagtcga tgcgccgggc ctggagccgc aacagggcgg ccaccgtctg gaggttgttc
    20581 ttcacccggt ggtggatctc ccggatggtc gcgtccttgg tgatcaactc gcgttcgcgg
    20641 cgccgcagtt cggtgacgtc ccggcacagc accagggccc cgatccgggt gcccttgggc
    20701 ttgagcggga tggaccggaa ctggatcacc ccgtcgggcg actcgatctc gaactcgcgc
    20761 ggcgcccagc cgctggccac cttggccagc gcctcgtcca ccgggccccg ggtgggggcg
    20821 agttcggcgg tggtgtgccc gaggtggtgt ccgaccaggt cggcggcgag gccgaggcgg
    20881 tggtaggcgg acagcgcgtt cggggaggcg tactggacga tgccgtcggc gtccagccgg
    20941 atcagtccgt cgccgacgcg cggggaggcg tccatgtcga cctgctggcc ggggaagggg
    21001 aaggacccgg ccgcgatcat ctgggcgagg tcggaggcgc tctggaggta ggtcagttcc
    21061 aggcggctcg gggtgcgcac ggtgagcagg ttggtgttgc gggcgatcac cccgaggacc
    21121 cggccctccc gtcgtac
//
