LOCUS       NZ_CP094483            22163 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces murinus strain JS029 chromosome.
ACCESSION   NZ_CP094483
VERSION     NZ_CP094483.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces murinus
  ORGANISM  Streptomyces murinus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Draft genome sequence of Streptomyces sp. JS029
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAR-2022) Agricultural Life Science, Sunchon National
            University, Jungangro 255, Suncheon, Jeonnam 57922, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-MAR-2021
            Assembly Method                   :: Unicycler v. 0.3.1
            Assembly Name                     :: JS029
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 164.82x
            Sequencing Technology             :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028753175.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 03:30:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,582
            CDSs (total)                      :: 7,481
            Genes (coding)                    :: 7,273
            CDSs (with protein)               :: 7,273
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 215
            CDSs (without protein)            :: 208
            Pseudo Genes (ambiguous residues) :: 0 of 215
            Pseudo Genes (frameshifted)       :: 110 of 215
            Pseudo Genes (incomplete)         :: 125 of 215
            Pseudo Genes (internal stop)      :: 20 of 215
            Pseudo Genes (multiple problems)  :: 41 of 215
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:08:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1754719
            Orig. end                         :: 1776882
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP094483.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from National Institute of
            Biological Resources.
FEATURES             Location/Qualifiers
     region          1..22163
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="13"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22163
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22163
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12163](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12163)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            553..1806
                     /locus_tag="ME763_RS07425"
                     /old_locus_tag="ME763_07420"
     CDS             553..1806
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006381321.1"
                     /locus_tag="ME763_RS07425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07420"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_085567141.1"
                     /transl_table=11
                     /translation="MSLLPELRYPSVPELVACARALAASEPGLCALRQVGRSRAGRPLH
                     LLSVGHAQRSVLVVAGAHANEPTGGSTLRVLAQRVLAERELRTGTSWHFLLCADPDGAA
                     LHVTPAPRSLLDYHLGFYRPTGAEQPEWSPSVLPPDRLPPETRTLTGVIDELRPYLQVT
                     LHGTDLGGSWVQLTRNVPGLAEPFAKSAAQLHIPVETGASDAAGWPASGPGVHVMPGPG
                     TDAAYPSMPDDARHSTWYHAHRYGGLTAVVEVPMWASDLVDDPAPHPAPAAAMRRLARR
                     LLRDSLEVERVLAEALPRLDGADGPLLRAARWALELIPGLAEDWTHTVPAASTMAYVGS
                     VDAFGRRLPLRAAAMLLRVLRESGDRAAPDLERLVATWSDAFARRFRARWVPLDHQVEH
                     QSRTVLLAAQQAREQACQ"
     gene            complement(1900..2307)
                     /locus_tag="ME763_RS07430"
                     /old_locus_tag="ME763_07425"
     CDS             complement(1900..2307)
                     /GO_function="GO:0004867 - serine-type endopeptidase
                     inhibitor activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071457.1"
                     /locus_tag="ME763_RS07430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07425"
                     /product="SSI family serine proteinase inhibitor"
                     /protein_id="WP_085567140.1"
                     /transl_table=11
                     /translation="MTYFTRATAAAGVLLAAAGLLAAGPAQAAPHLHGNRLHLAITRSG
                     ARADSGRSALLRCLPPHGHPYAAEACAELTAARGDIDRIPARKVFCPRIYSPVTATARG
                     RWNGRTVDFRRTYTNSCELRARTGSVFDLGD"
     misc_feature    complement(2307..2323)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            complement(2398..2958)
                     /locus_tag="ME763_RS07435"
                     /old_locus_tag="ME763_07430"
     CDS             complement(2398..2958)
                     /GO_function="GO:0051219 - phosphoprotein binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385491.1"
                     /locus_tag="ME763_RS07435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07430"
                     /product="DUF1707 and FHA domain-containing protein"
                     /protein_id="WP_037655461.1"
                     /transl_table=11
                     /translation="MTSSFEFPTAPAPASARLSDTEREAALEVLRDGAAKGRLSHETFV
                     RRMELALAARHADELAVLVADLPRDNRFSRAIFGTVEAVSGFTVRLRRAWQAERLPKLL
                     LPGPAHTRLRIGRDPGNGLRLTHETVSRVHAELSRQGGLWILRDLGSTNGTTVNGRRVV
                     GAVAVREGDQVAFGRVAYRLSLS"
     gene            3161..4906
                     /gene="treZ"
                     /locus_tag="ME763_RS07440"
                     /old_locus_tag="ME763_07435"
     CDS             3161..4906
                     /EC_number="3.2.1.141"
                     /GO_function="GO:0033942 -
                     4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675705.1"
                     /locus_tag="ME763_RS07440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07435"
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="WP_085567139.1"
                     /sec_met_domain="Alpha-amylase (E-value: 5e-11, bitscore:
                     41.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFEVWAPQADRVTLQCEGATRALTRDPERAGWWKGEATAADGAR
                     YGFALDDGPVLPDPRSRRQPDGPDGLSAVVDQERYRWRVPWPGRELPGAVLYELHVGTF
                     TPEGTLDAAAARLGHLVELGITHVELMPVCPFPGRHGWGYDGVSPWAVHEPYGGPEALK
                     RFVDRAHELGLGVVLDVVHNHLGPSGNHLPSFGPYFTDTHTTPWGAAVNLDAPGSDEVR
                     AFLVGGALAWLRDFRLDGLRLDAVHALYDTRATHFLEELSAAVDRLAAEVGRPLFLIAE
                     TDLNNPRFITPRTENGLGLHAQWNDDFHHALHTALTGESQGYYADFARDPFAALAKTLT
                     GGYFHDGTYSGFRERHHGRPLDRALVAGHRLLGYSQTHDQIGNRAQGDRLSAHLSPGLL
                     ACAATLVLTAPFTPMLFMGEEWAAGTPWQYFADHTDPALAQAVRSGRRREFAAHGWAEE
                     DVPDPGDPATRERSCLDWSEPERVAHARVLDWYRRLIALRRDQPDLTDPDLADTKVAYD
                     GRARWLAFRRGDVRVAVNLGKEAAAIPLGSRPALVLAAWEPVEPPGPDGMLQLPGESCV
                     VLSQP"
     gene            complement(4931..5863)
                     /locus_tag="ME763_RS07445"
                     /old_locus_tag="ME763_07440"
     CDS             complement(4931..5863)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133694.1"
                     /locus_tag="ME763_RS07445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07440"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_085567138.1"
                     /sec_met_domain="APH (E-value: 1.6e-15, bitscore: 56.4,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAPTPTADTVRQLVRSLLKEGPEGDGPDVRPVREGHAYTWWVG
                     TRQVLRLAPDREASTRRRRELRLRALVRPHVPVAVPVSVAHADWAPGLACTLDTVVPGG
                     TAEEHEVSAAGEADLAGLLTGLRAVPVRQAESLGVPRAAPRSLEALRRMAVHAAEQLAA
                     ADEFDAAPMYQLTPAGAAQLAAQPGVAVLTHHGLTGEHVVVSADGRVRGILDWTEVALG
                     DPAEDIAGLAVAVGSPAAVRAATLAGYGARPCLRGLWLARCDTVLRLADRLDGRTCGDP
                     TLLRTQLRRAWEPILLERVTDFKTAGEEP"
     gene            complement(5938..7065)
                     /locus_tag="ME763_RS07450"
                     /old_locus_tag="ME763_07445"
     CDS             complement(5938..7065)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009191280.1"
                     /locus_tag="ME763_RS07450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07445"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_085567137.1"
                     /transl_table=11
                     /translation="MTGTTTTPFSAADHKARMERAARAAADAGLAGLLVAPGPDMVWLT
                     GYTPTAVTERLTLLVLAPGQDPVLVVPTLEAPDAEHSVAGEALTLRDWTDGKDPYAVTA
                     ELLDGRGRYGISDNTWGMHVLGLQRTLPDSSYAALTDALPMLRAVKDAAEVQLLAAAGA
                     AADAAFEEIRKVTFAGRRESDLGRDLAALLRRFGHSQVDFTIVGSGPNGANPHHEVGDR
                     VIQRGDMVVLDFGGLKDGYGSDTTRTVHVGEPTEEERRVHDIVREAQEAGYQAVRPGVA
                     CQEVDRAARKVITDAGYGEYFIHRTGHGIGVTTHEPPYMIEGEELPLVPGMCFSVEPGI
                     YLPGRFGVRIEDIVTVTEDGGRRLNNTGREMVTVD"
     gene            complement(7322..7843)
                     /locus_tag="ME763_RS07455"
                     /old_locus_tag="ME763_07450"
     CDS             complement(7322..7843)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657043.1"
                     /locus_tag="ME763_RS07455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07450"
                     /product="PDZ domain-containing protein"
                     /protein_id="WP_085567136.1"
                     /transl_table=11
                     /translation="MEHTALRPRPLPGRGPRVGGGPAHHPHAANRRRRRLRTLLLGACA
                     GTLLVLSGVGIGAVGATVLGGAGETAPQPRATAAPARDSGPRATLGVEAVDYGSPGALV
                     VGVHTPGPGYRAGLARGDVLLQFGGARVDTAADLARAVARARPGSEVLLTVRHSGGGFQ
                     QLTVVPGVVT"
     misc_feature    7987..8005
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.67"
                     /tool="antismash"
     gene            complement(7998..9869)
                     /gene="phsA"
                     /locus_tag="ME763_RS07460"
                     /old_locus_tag="ME763_07455"
     CDS             complement(7998..9869)
                     /EC_number="1.10.3.4"
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0050149 - o-aminophenol oxidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="phsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675701.1"
                     /locus_tag="ME763_RS07460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07455"
                     /product="O-aminophenol oxidase PhsA"
                     /protein_id="WP_085568809.1"
                     /transl_table=11
                     /translation="MEKAVERITGATGEKKRAPGELRPYVAPLTVPPVLRPTSADVRQE
                     TEIALRPTWVRLHPQLPPTLMWGYDGHVPGPTIEVRRGRRIRIAWTNRIPKDAEYPVTA
                     VAVPVRAPGAAPATTEPGRGGAEPDKDVAALPAWTVTHLHGAQTGGGNDGWADNAVGSG
                     DAQLSEYPNDHQATQWWYHDHAMNITRWNVMSGLYGTYLVRDDEEDALHLPSGEREIPL
                     LLADRNLDTDEDGRLNGRLLHKTVVVQQSDPETGKPVTIPFSGPYTTVNGRIWPYAEVD
                     SAWYRFRLVNASNARIFDLVLIDEDGDPVPGIVHQIGSDGGLLPRPVPVDFGAELPTLT
                     AAPAERFDLLVDFRRLAGRTLRLVNKGPDQPAGVPDPAGDVRCPAVMEFRVRKAAEHDT
                     FELPEVLSGSFRRLTHDLPHGHRLVVLTPPATKGAGGHPEIWEMTEVTDTDGPVLPADG
                     VIRLTGPDGTTKTYRRIARTFNDGLGFTIGEGSYEQWSFLNLAPIVHPMHIHLADFQLL
                     GRDVYDVSGFDPVVGGTRSPIRHDAGTAIPLAPNEQGHKDVFRVPGGQLLRVMGRFDGA
                     YGRFMYHCHLLEHEDMGMMRPFVVMPAEAMKFDHGATHDGGHGGHMG"
     misc_feature    complement(9868..9881)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.28"
                     /tool="antismash"
     gene            complement(10001..12163)
                     /gene="cyc2"
                     /locus_tag="ME763_RS07465"
                     /old_locus_tag="ME763_07460"
     CDS             complement(10001..12163)
                     /EC_number="4.1.99.16"
                     /EC_number="4.2.3.22"
                     /EC_number="4.2.3.75"
                     /codon_start=1
                     /gene="cyc2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034221.1"
                     /locus_tag="ME763_RS07465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07460"
                     /product="germacradienol/geosmin synthase Cyc2"
                     /protein_id="WP_085567135.1"
                     /sec_met_domain="T1TS (E-value: 1.1e-81, bitscore: 274.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFELPHFYMPFPARLNPHLDEARSHSTAWAREMGMLEGSGIW
                     DQADLDAHDYGLLCAYTHPDCDGAALSLITDWYVWVFFFDDHFLDMFKRTQDRAAGKAH
                     LDRLPLFMPIDPATPVPEPENPVEAGLKDLWARTVPAMSVDWRRRFSVATEHLLNESMW
                     ELSNINEGRIANPVEYIEMRRKVGGAPWSAGLVEYATAEVPASVAETRPLRVLMETFAD
                     AVHLRNDLFSYQREVEDEGENSNGVLVLETFFGCTTQQAADTVNDILTSRLHQFEHTAL
                     TEVPAIALEHRLTPAETGAIAAYAKGLQDWQSGGHEWHLRSSRYMNKGARNDSPWMLPS
                     GPGTSAARIGALLASAAHERLRAYSHVPHQKVGPSILPEFHMPFALELSPHLDATRRNL
                     RAWCDQVGILQEGVWDEDKLRAYDLALCSAGLDPDATPEALDLSAQWLAFGTYGDDYYP
                     LVYGHRRDLAAARLTTARLSACMPVDGEPPLVPGNAMERSLIDLWARTTAAMSTGQRRT
                     LKAAVDTMTESWVWELSNQLQNRIPDPVDYLEMRRATFGSDLTLSLCRMGRGPAVPPEV
                     YRSGPVRSLENAAIDYACLLNDIFSYQKEIEYEGEIHNAVLVVQNFFGVDYPTALGVVH
                     DLTTQRMRQFEHVAAHELPVLYEDFGLSPQARAAVDGYVDDLRNWLAGILNWHRSVDRY
                     KDAWLSRRAHGFLPDRPPVRPLLTPG"
     gene            12297..13079
                     /locus_tag="ME763_RS07470"
                     /old_locus_tag="ME763_07465"
     CDS             12297..13079
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (19-148). E-value:
                     1.3e-21. Score: 69.2. Matches aSDomain:
                     nrpspksdomains_ME763_RS07470_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983604.1"
                     /locus_tag="ME763_RS07470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07465"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_085567134.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6e-18, bitscore:
                     65.0, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.2e-17, bitscore: 63.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSFVLPHEVHGDGAHRVFAVHGWFADRSAYAAVLPDLDRTSFTY
                     VPVDLRGYGEAADAPGPYTTAQAAVDLVALADRLGWARFSVIGHSMGGAVAQRLLALAP
                     ERLRRIVGVSPVPAAGMPLSGEQGALFMDAAHKAGNRRAIIDFTTGGRRPAAWLDRMVW
                     TSFQRSDAKAFRAWLDSWAGEDFHAEVTGSEVPALAVAGELDPALSPDLMRQTWLSWYR
                     HGDLVALPGAGHYAMDETPLELIRVVEDFLRADGSDRA"
     aSDomain        12354..12740
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ME763_RS07470_Abhydrolase_1.1"
                     /evalue="1.30E-21"
                     /label="ME763_RS07470_Abhydrolase_1.1"
                     /locus_tag="ME763_RS07470"
                     /protein_end="148"
                     /protein_start="19"
                     /score="69.2"
                     /tool="antismash"
                     /translation="AVHGWFADRSAYAAVLPDLDRTSFTYVPVDLRGYGEAADAPGPYT
                     TAQAAVDLVALADRLGWARFSVIGHSMGGAVAQRLLALAPERLRRIVGVSPVPAAGMPL
                     SGEQGALFMDAAHKAGNRRAIIDFT"
     CDS_motif       12552..12587
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ME763_RS07470_0001"
                     /evalue="4.00E-04"
                     /label="NRPS-te1"
                     /locus_tag="ME763_RS07470"
                     /protein_end="97"
                     /protein_start="85"
                     /score="13.0"
                     /tool="antismash"
                     /translation="VIGHSMGGAVAQ"
     gene            13076..14338
                     /locus_tag="ME763_RS07475"
                     /old_locus_tag="ME763_07470"
     CDS             13076..14338
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983605.1"
                     /locus_tag="ME763_RS07475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07470"
                     /product="cytochrome P450"
                     /protein_id="WP_085567133.1"
                     /sec_met_domain="p450 (E-value: 6.3e-17, bitscore: 60.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTGTTAPVPDVFDPRRYACGVPYDAYRVLRDAHPVAWQEEPEVL
                     GWPAGPGFWAVTRHADVVRVLKDSAGYSSHLGATQIRDPDPEDLPFVRRMMLNQDPPRH
                     GRLRRLVSRAFTPGRIERFAALARERARTLLATARERAGRGDGTVDLVTAVTDEYALLN
                     LTDLLGVPDGDRRLLLHWTRRVIGYQDPDEAAPPVLDGSGKPLNPRSPAMLRDMFGYAH
                     ELAAHKRRHPADDIMTTLATDPELTGPELEMFFFLLTVAGNDTVRSAAPGGLQALAEHP
                     RSYDLLRTGKAELAPAVDELLRWHPPVLTFRRTAAQDTELAGRRIPAGDKVVVFHASAN
                     RDERAFADPGRLDLARSPNPHVSFGDGPHVCLGAHFARLQLRLLYAEVARALPELRPAG
                     PAERLVSNFINGLKSLPVQVG"
     gene            complement(14310..15506)
                     /locus_tag="ME763_RS07480"
                     /old_locus_tag="ME763_07475"
     CDS             complement(14310..15506)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523405.1"
                     /locus_tag="ME763_RS07480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07475"
                     /product="damage-control phosphatase ARMT1 family protein"
                     /protein_id="WP_107437323.1"
                     /transl_table=11
                     /translation="MPETPFASVILGNEPGSFPHGVLAERHPAIIRQVRDAFPYGPGQH
                     RALDELLKSCAEGTVAPLPADAPDRAAWHAWGLAEYAGQSWFDVPWLWSESYFYRRLLE
                     AVGYFTPGPWRGIDPFRPVKRAELDAPETDRELAALDDLRDLPEPERGRALLHGSLWGN
                     RADLGFRLSAEGAEAREPAPALVADDSERLWSLLPPGGGADLVLVADNAGRELVPDLLL
                     IAHLLAGGRIARAVLQVKPYPYYVSDAIMADVLDGLERLRTAPGAAGELGRLLRSAMAD
                     GRLTVRAHPFFCAPLPYERMPPDLRAEFAAAGLTLFKGDLNYRRLVGDRRRPPTTSFAA
                     ATAYFPGPVAALRTLKSEVITGLTAATEARLVAAEGQRWRTDGTHALIQVNRPVREGT"
     gene            complement(15529..16173)
                     /locus_tag="ME763_RS07485"
                     /old_locus_tag="ME763_07480"
     CDS             complement(15529..16173)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675696.1"
                     /locus_tag="ME763_RS07485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07480"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_037655450.1"
                     /transl_table=11
                     /translation="MARQLRAEQTRATIITAAADLFDQHGYESTSLSDIVAHAKVTKGA
                     LYFHFAAKEDLAHAILELENRAARRLVADLDGRGYSSLEGLMRTTFGIARLAVDDPVPR
                     AGLRLATADVTVRPPLRHPYTEWLEFAARKFTGAVREADVHGDLDVSAAAHSLVCFFFG
                     TRVAGRFEPVGRLPRRVAEMWHLMIRGLVPVHRRPRYVTLATQLEREIRTA"
     misc_feature    complement(16159..16161)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16483..17133)
                     /locus_tag="ME763_RS07490"
                     /old_locus_tag="ME763_07485"
     CDS             complement(16483..17133)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675693.1"
                     /locus_tag="ME763_RS07490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07485"
                     /product="Tat pathway signal sequence domain protein"
                     /protein_id="WP_085567131.1"
                     /transl_table=11
                     /translation="MRTRTLIALAATASATVLALVSAGPASAAGTVLTTGSAGGTAVAV
                     GDTLTAPLASGTSATFYSSSTGTSGVKCGTSQFTAKVTANPTAPGTATESLTGQTFSGC
                     TSNVTGVLGVSGVTIDNLPYTAAAASAGTLTVTPPSGSVIQSTVKLSTLLGSVTCVYQG
                     PSLAGKTANADNSITFTNQQFTKTSGSSLCFSTAYFSAKYAPVTDGGASVYVN"
     misc_feature    17676..17691
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.09"
                     /tool="antismash"
     gene            17872..18567
                     /locus_tag="ME763_RS07495"
                     /old_locus_tag="ME763_07490"
     CDS             17872..18567
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996942.1"
                     /locus_tag="ME763_RS07495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07490"
                     /product="DUF6230 family protein"
                     /protein_id="WP_085567130.1"
                     /transl_table=11
                     /translation="MASSPDLSSTGNTPENPESGSPSEAPSGTAAPAAGRRGRVRARRA
                     AVMAVPATLVAAGLAVLTAQGALGVQFSISGMPFTVAASQLDGTGFEQFGGLDNMADGS
                     PNAGDTGGQVLIVTSAIKKATLTKLCQSVDLGGTNLLITAGGGDTKVSASDLTTDSTEM
                     SGDASFNHIEIGNDASTLTEANAKGPIGVFSQQADSVHIDNLRQTNYATTAGVFKLPGL
                     KLRFSDSGC"
     gene            18573..19013
                     /locus_tag="ME763_RS07500"
                     /old_locus_tag="ME763_07495"
     CDS             18573..19013
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675691.1"
                     /locus_tag="ME763_RS07500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07495"
                     /product="DUF6114 domain-containing protein"
                     /protein_id="WP_274506102.1"
                     /transl_table=11
                     /translation="MEESPRPVPRRSFRAWRARRPFWGGLLLALGGGEILLTEKASLKV
                     VMHIGMQGLAGYLLPVLMALLGLLVLFNPTQRLFYSILGVLASLGTWVTSNLGGFFIGL
                     LLGVVGSCLAFGWLPDQEPRVSRRKRRRRARALAEEAGTSAV"
     gene            19112..19567
                     /locus_tag="ME763_RS07505"
                     /old_locus_tag="ME763_07500"
     CDS             19112..19567
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675687.1"
                     /locus_tag="ME763_RS07505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07500"
                     /product="TerB family tellurite resistance protein"
                     /protein_id="WP_085567128.1"
                     /transl_table=11
                     /translation="MALWDRVKESASQMQNQLVAKKNDLKSGAFRDASMAMCALVAAAD
                     GTVDPSERQRVAQLIATNEVLQNFPADDLRRRFEDNLNKLTTDFAFGKVSVLQEIAKAK
                     KKPAEARAVIQIGIVIGGADGDFDKTEQSVVREACFTLELPPHEFDL"
     misc_feature    complement(19144..19158)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.24"
                     /tool="antismash"
     gene            complement(19630..20172)
                     /locus_tag="ME763_RS07510"
                     /old_locus_tag="ME763_07505"
     CDS             complement(19630..20172)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS07510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ME763_07505"
                     /product="hypothetical protein"
                     /protein_id="WP_161217589.1"
                     /transl_table=11
                     /translation="MMKRRALSAALAAGTATLAMVMSTGAAQAEDIPGFVNKVTVGSGT
                     RTVYTGHTELDQSTLSGCLSNAWIQGHATWTLGNVTKTSIVVKSIQVFYRAGVTSYVGE
                     QYLLRGNNSSVWSKVASGDVPGDTRDRSETYAINKTVPLDGKSTITFWSYFSLGRTGGP
                     ADCGGQSTFTYKLQPVS"
     misc_feature    complement(20212..20221)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    20287..20301
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.65"
                     /tool="antismash"
     gene            20339..21430
                     /locus_tag="ME763_RS07515"
                     /old_locus_tag="ME763_07510"
     CDS             20339..21430
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1015: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF025878.4"
                     /locus_tag="ME763_RS07515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_07510"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_172427675.1"
                     /transl_table=11
                     /translation="MAHGDFGTRHLKAAERLAAADELFGRGLLPMRLLNRAGDTFEASV
                     RHVDLAPLTVVKFSATPAAVLRTPRLIRRGDPEMLSLIVPVDAGLTVGQVGRETVVRAD
                     EMALYDSSQPFRIQVTAESAVPGVTTVVSLHAPRALLGLPPGGLDPLLARPLPAGRGAL
                     FGRTLHQILSDVIEDGTGHRPVDLARLGHVALDLVTALVAHHLEAEALVPESVQHRTLL
                     LRVDSFIRQRLHDVTLSPATVAAAHHISVSHLHRLFEPRRTTVAASIRRQRLERARRDL
                     ADPALRDMPVHRIADRWGFRGHSTFTRAFRAAFGTSPQDYRNSALAAAADERRWDGACR
                     EASWSCQENSRSSMPRDSRPPWE"
     gene            complement(21473..21724)
                     /locus_tag="ME763_RS07520"
                     /old_locus_tag="ME763_07515"
     CDS             complement(21473..21724)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS07520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ME763_07515"
                     /product="hypothetical protein"
                     /protein_id="WP_143657415.1"
                     /transl_table=11
                     /translation="MAEVGGARLTDGPVPPGLADPVPAAGPVGVGEAGLDALVTRYGVV
                     AVLAGPDRGGAYLARSLLSDPKRIRGRLDEAPTSEAKR"
     misc_feature    21945..21961
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.59"
                     /tool="antismash"
ORIGIN
        1 ccgaagggct ggtcgtcgcc gagaccctcg cggggctgcg gcccgcgccg gtcgactaca
       61 cggccgtacc ccgggtgacg tactcctcgc cgcagaccgc cgccgtcggg ctcacggagg
      121 cgcaggcgcg ggcgctgggg cacgagcccg ccgtgcgcgc catgccgctc accgcgctgg
      181 cgaagggaat ggtgcacggc cggggcggca tggtgaaggt ggtcgccgag gccagtggcg
      241 ggcgggtgct cggggtgcat ctggtcggcc cgcaggtctc ggaactgatc gccgaggccc
      301 agctgatcgt cggctgggac gccgaacccg ccgatgtggc ccggcatgtg cacccgcatc
      361 ccacgctctc ggaggcgatg ggcgaggtgt tcctgacgct cgcgggacgg gggctgcacc
      421 agcggtgagc accgtgaatg cggtggcacc ggctccggtt ggcacatgcc gagggggcat
      481 ccggccggac gcttgacagc caccgcgcac cgtgcgggac tgggagggcg aagcagggcg
      541 gacgaatcgg gggtgagtct cctgccggag ctgcgctatc ccagcgttcc cgaactggtg
      601 gcctgcgcac gggcgttggc cgcttcggag cccgggctgt gcgcgctgcg gcaggtgggc
      661 cgctcacgcg cgggacgccc cctgcatctg ctgtcggtgg ggcacgcaca gcggtcggtg
      721 ctggtggtgg cgggcgccca cgccaacgaa ccgaccggcg gctccacttt gcgggttctg
      781 gcacaacgag tcctggccga acgcgagttg cgcaccggca cctcctggca cttcctgctg
      841 tgcgcggacc cggacggcgc cgccctccat gtcaccccgg ccccacgcag cctgctcgac
      901 taccacctcg gcttctaccg gcccaccggc gccgagcagc cggagtggtc gccctccgtg
      961 ctgcccccgg accggctgcc gcccgagacc cggaccctga ccggggtgat cgacgagctg
     1021 cgcccctacc tccaggtgac cctgcacggc accgatctgg gcggcagctg ggtgcagttg
     1081 acccggaacg tgccgggcct cgcggagccg ttcgccaagt cggcggcgca gctgcacatc
     1141 ccggtggaga cgggcgcctc ggacgccgcg ggctggccgg cgtccgggcc cggggtgcat
     1201 gtgatgccgg ggcccgggac ggacgcggcc tacccgagca tgccggacga cgcccggcac
     1261 agcacctggt accacgcgca tcgctatggg ggtctgaccg ccgtggtgga ggtgccgatg
     1321 tgggccagtg acctggtgga cgacccggcg ccgcacccgg caccggccgc ggcgatgcgg
     1381 cggctggccc ggcggctgct gcgggactcg ctggaggtgg agcgggtgct ggcggaggcg
     1441 ctgccccggc tcgacggcgc cgacgggccg ctgctgcggg ccgcgcgctg ggcgctggag
     1501 ctgatcccgg gcctggccga ggactggacc cacaccgtgc cggccgcctc cacgatggcg
     1561 tacgtcggca gcgtggacgc gttcggacgg cggctgccgc tgcgggcggc cgcgatgctg
     1621 ctgcgggtgc tgcgggagag cggcgaccgg gcggcgccgg acctcgaacg gctcgtggcc
     1681 acctggtccg acgccttcgc ccggcgcttc cgggcccgct gggtgcccct ggaccaccag
     1741 gtggagcacc agtcgcgcac ggtgctgctg gcggcccagc aggcccggga gcaggcgtgt
     1801 caatagggcc accggtcggt gcggcgtggc ctcgcgccgc cggcggatgc ggcggagcct
     1861 ggcgccgccg gccggtgcgg cggagccgcg cgccgccggt cagtcgccga ggtcgaagac
     1921 cgagcccgtg cgcgcccgca gttcgcagga attggtgtac gtccgccgga agtcgaccgt
     1981 ccggccgttc cagcggccgc gcgcggtggc ggtgaccggg gagtagatcc gcgggcagaa
     2041 caccttgcgg gccgggatgc ggtcgatgtc gccgcgggcg gcggtcagtt cggcgcaggc
     2101 ctcggccgcg tacggatggc cgtggggcgg caggcagcgc agcagggcgc tgcggccgct
     2161 gtcggcccgg gcgcccgagc gggtgatcgc gaggtgcagc cggttgccgt gcagatgggg
     2221 tgccgcctgg gcggggcccg cggcgaggag accggcggcg gccaggagca cgccggcggc
     2281 cgctgtcgct ctggtgaagt acgtcatgcc cgttgcatcg gcaggacgtc cggcgttccg
     2341 cagtgcgggt cacccgttcg aacgaccgag gcgccgcggc cgcgcgctca gctcagctca
     2401 gctcagcgac agccggtacg ccacccgccc gaacgccacc tggtcgccct cgcggaccgc
     2461 gaccgcgccg accacccggc ggccgttgac ggtggtcccg ttggtggagc cgagatccct
     2521 gaggatccac agcccgccct gcctgctgag ttcggcgtgc acccgggaga ccgtctcgtg
     2581 cgtcagccgc agcccgttgc ccggatcgcg gcctatccgc agccgggtgt gggccggtcc
     2641 cggcagcagc agcttgggca gccgctcggc ctgccaggcg cggcgcagtc gtaccgtgaa
     2701 accggagacg gcctcgacgg tgccgaagat cgcgcgggag aagcggttgt cgcggggcag
     2761 gtcggcgacg agtacggcga gttcgtcggc gtgccgcgcg gcgagcgcca gttccatgcg
     2821 acgcacgaac gtctcgtgcg acagccggcc cttggccgcg ccgtcccgca gcacctccag
     2881 cgccgcttcc cgctccgtgt cggacagccg cgcggacgcc ggggccgggg cggtggggaa
     2941 ctcgaaggac gacgtcacgc ctgtgattgt cggtcagtgg gcggcgggtg tccagaaagc
     3001 gggtgatccg cgcccgcccg ccggtacttc cgcgcggccc gccgggaaac atcgcacgac
     3061 acctggaggg aaagggcccg atcgaagggg agatcggcgg tgggggcggg cacgatggga
     3121 gcgcgggaca tcacggtgaa cagacgaagg ggaaccgtcc gtgcagttcg aggtgtgggc
     3181 accgcaggca gaccgggtga cgctccagtg cgagggcgcc acgcgggcgt tgacgcgcga
     3241 tccggagcgc gcgggctggt ggaaggggga ggcgacggcg gctgacggcg cccggtacgg
     3301 attcgcgctg gacgacggtc cggtgctgcc cgacccgcgt tcgcgccggc agccggacgg
     3361 tcccgacggg ctcagcgcgg tcgtggacca ggagcggtac cggtggcggg tgccgtggcc
     3421 ggggcgggag ttgccgggcg cggtgctcta cgagctgcat gtgggcacgt tcacccccga
     3481 gggcaccctg gacgcggcgg cggcccggct cggtcatctg gtggaactgg gcatcaccca
     3541 cgtggagttg atgccggtat gcccgttccc cgggcggcac ggctgggggt acgacggggt
     3601 gtcgccgtgg gcggtgcacg agccgtacgg cggccccgag gcgctgaagc ggttcgtgga
     3661 ccgggcgcac gagctgggcc tcggagtcgt actggacgtc gtgcacaacc acttggggcc
     3721 ctccggcaac catctcccgt ccttcgggcc ctacttcacc gacacgcaca ccacgccatg
     3781 gggcgcggcg gtgaacctgg acgcgcccgg ttcggacgag gtgcgcgcct tcctcgtcgg
     3841 cggcgcgctc gcctggctgc gggacttccg gctggacggg ctgcgccttg acgcggtgca
     3901 cgcgctgtac gacacccggg ccacccattt cctggaggag ctgtcggcgg ccgtcgaccg
     3961 gctcgcggcg gaggtgggcc ggccgctgtt cctgatcgcc gagaccgacc tcaacaaccc
     4021 gcgcttcatc accccgcgca cggagaacgg gctcgggctg cacgcgcagt ggaacgacga
     4081 cttccaccac gccctgcaca ccgcgctgac cggcgagtcc cagggctact acgcggactt
     4141 cgcgcgcgat cccttcgccg cgctggccaa gacgctcacc ggcggctact tccacgacgg
     4201 cacgtactcc ggtttccggg agcggcacca cgggcggccg ctggaccgcg cgctggtcgc
     4261 cgggcaccgg ctgctcggct actcccagac ccatgaccag atcggcaacc gcgcccaggg
     4321 cgaccggctt tcggcgcacc tctcccccgg tctgctggcc tgcgcggcga cgctggtgct
     4381 gaccgcgccg ttcaccccga tgctgttcat gggcgaggag tgggcggccg gcacaccttg
     4441 gcagtacttc gccgaccaca cggaccccgc tctcgcccag gcggtacgaa gcgggcggcg
     4501 ccgggagttc gcggcgcacg gctgggccga ggaggacgta cccgacccgg gggacccggc
     4561 gacccgggag cgctcctgcc tggactggtc ggagcccgaa cgcgtcgcgc acgcacgggt
     4621 gctggactgg taccggcggc tgatcgcgct gcgccgcgac cagccggacc tcaccgaccc
     4681 ggatctcgcc gacacgaagg tggcctacga cgggcgggcc cgctggctgg ccttccggcg
     4741 gggcgacgta cgggtcgcgg tgaacctggg caaggaagcg gccgccatcc cgctgggctc
     4801 ccgcccggcc ctggtcctcg ccgcgtggga gccggtcgaa cccccgggcc cggacggcat
     4861 gctccagctg cccggggagt cgtgcgtggt gctcagccag ccctgagcag tcctgagggg
     4921 gagaagcccg ttacggctcc tcccccgccg tcttgaagtc cgtcacccgc tccagcagga
     4981 tcggctccca cgcccggcgc agctgggtgc gcagcagggt cgggtcgcca caggtccggc
     5041 cgtcgaggcg gtccgcgagg cgcagcaccg tgtcgcagcg cgccagccac aggccgcgca
     5101 ggcaggggcg ggcgccgtac ccggcgaggg tggcggcgcg gacggcggcc ggggagccga
     5161 cggcgacggc gagccccgcg atgtcctcgg cgggatcgcc gagcgccacc tcggtccagt
     5221 cgaggatgcc gcgcacccgc ccgtcggcgc tgaccaccac gtgttcgccg gtgagcccgt
     5281 ggtgggtgag cacggcgaca ccgggttgcg cggcgagctg ggcggccccg gccggggtga
     5341 gctggtacat cggcgctgcg tcgaactcgt cggcggcggc gagctgttcg gccgcgtgca
     5401 ccgccatccg gcgcagcgcc tccagggagc gcggggcggc gcgcggcaca ccgagcgact
     5461 cggcctgccg taccggcacc gcgcgcaacc cggtgagcag accggcgaga tcggcctcgc
     5521 cggccgccga gacctcgtgc tcctcggcgg tgccgccggg caccacggtg tccagggtgc
     5581 aggcgaggcc gggcgcccag tcggcgtgcg cgacgctgac cggcaccgcg accgggacgt
     5641 gcgggcggac cagggcacgc agccgcagtt cccggcggcg gcgggtggac gcctcccggt
     5701 cgggggcgag gcgcagcacc tggcgggtgc cgacccacca ggtgtacgca tgcccctccc
     5761 gtacgggccg gacgtcgggt ccgtcgccct cggggccttc cttgagcagc gaacggacca
     5821 gctggcggac ggtgtccgcg gtgggggtcg gtgcctgggt catggatcgc gcgttgccgt
     5881 tccgggtgtc gtcggaggtg gtcgccccgg gcccgccccg ggcccgggtc cgtgccgtca
     5941 gtccactgtc accatctcgc gtccggtgtt gttgaggcgg cggccgccgt cctcggtcac
     6001 cgtcacgatg tcctcgatgc gcaccccgaa ccggccgggc agatagatgc cgggctccac
     6061 cgagaagcac atcccgggca ccagcggcag ctcctcgccc tcgatcatgt acggcggctc
     6121 gtgcgtggtg acgccgatgc cgtgcccggt gcggtggatg aagtactcgc cgtacccggc
     6181 gtcggtgatc accttgcggg ccgcccggtc gacctcctgg caggccacgc cgggccgtac
     6241 cgcctggtag ccggcctcct gggcctcgcg cacgatgtca tggacccggc gctcctcctc
     6301 ggtgggctcg ccgacgtgca cggtgcgcgt ggtgtcggag ccgtaaccgt ccttcaggcc
     6361 gccgaagtcg aggacgacca tgtcgccgcg ctggatgacg cggtcgccga cctcgtggtg
     6421 cgggttggcg ccgttggggc cggagccgac gatggtgaag tcgacctggg agtggccgaa
     6481 gcggcgcagc agcgcggcga ggtcccggcc gaggtcggac tcgcggcgcc cggcgaaggt
     6541 caccttgcgg atctcctcga acgcggcgtc ggccgcggct ccggcggccg cgagcagctg
     6601 cacctcggcg gcgtccttga ccgcgcgcag catgggcagg gcgtcggtga gggcggcgta
     6661 cgagctgtcg ggcagggtgc gctggaggcc gaggacgtgc atgccccagg tgttgtcgct
     6721 gatgccgtag cggccgcggc cgtcgagcag ctcggcggtg acggcgtagg ggtccttgcc
     6781 gtcggtccag tcgcgcaggg tgagcgcctc gcccgccacg gagtgctcgg cgtccggggc
     6841 ctccagggtg gggacgacga ggacggggtc ctggccgggg gcgaggacca gcagggtgag
     6901 ccgctcggtg acggcggtgg gggtgtagcc ggtcagccac accatgtccg gtcccggcgc
     6961 cacgagcagc ccggcgagac cggcgtcggc cgcggcgcgc gcggcgcgct ccatgcgggc
     7021 cttgtggtcg gctgcgctga agggcgtggt cgtcgtaccg gtcatccggg cctccggggg
     7081 gttctggctg gtcgggcggg tggcagggcg cgcggaaggc gccccgggca gcatcctgcc
     7141 cgcccgcacc gggccacgcg acccgatcgg acgatcccgc gtccaccggg ccacgcgacc
     7201 cgaccggcgg atcccgcgtc cgccgggcac ggcggagatc cgcgcggggc gggtcacggg
     7261 ggtcggcagg acgtccggca cccggccatc atgacccacc ggcccccggt ttccgcggcg
     7321 ctcaggtcac cacgcccggc accaccgtca actgctggaa gccgccgccg ctgtgccgca
     7381 cggtcagcag gacctcgctg ccggggcggg cgcgggcgac ggcccgtgcc aggtcggcgg
     7441 cggtgtcgac acgggcgccg ccgaactgga gcaggacgtc cccgcgggcc aggccggccc
     7501 ggtagccggg gccgggcgtg tgcacgccca ccaccagcgc gccggggctg ccgtagtcga
     7561 cggcctccac gcccagggtg gcccgggggc cgctgtcccg cgcgggcgcc gccgtggccc
     7621 ggggctgcgg cgcggtctcc cctgccccac cgagcacggt ggcgccgacc gcgccgatgc
     7681 ccacgccgga cagcaccagc agggtgcccg cgcaggcgcc gagcagcagg gtccgcagcc
     7741 gccggcggcg ccggttcgcg gcgtgcggat ggtgggcggg cccgccgccc acccgggggc
     7801 cccggcccgg cagcggcctg ggccgcaacg cagtgtgttc catggttcgt tcgcctccgg
     7861 ccggtcatct acccggcgca ccggcccatg acgagacacg aacgagtgag actggccgga
     7921 ggccggcggc gggtagtcac tacggacgcc ccgcacaccg gccccccagc tccggtccag
     7981 ggccgctcag ggtcggctca gcccatgtgc cctccatggc cgccgtcgtg cgtcgcgccg
     8041 tggtcgaact tcatcgcctc ggccggcatc acgacgaacg ggcgcatcat gcccatgtcc
     8101 tcgtgctcca gcagatggca gtggtacatg aacctgccgt acgccccgtc gaagcggccc
     8161 atgacccgca gcaactggcc gccgggcacc cggaagacgt ccttgtggcc ctgctcgttg
     8221 ggggcgagcg gaatcgcggt gcccgcgtcg tggcggatcg ggctgcgggt gccgccgacc
     8281 accgggtcga agccggagac gtcatagacg tcccggccca gcagctggaa gtcggccagg
     8341 tggatgtgca tggggtgcac gatgggcgcg aggttgagga agctccactg ctcgtagctg
     8401 ccctcgccga tggtgaatcc gagcccgtcg ttgaaggtcc gcgcgatgcg ccggtacgtc
     8461 ttggtggtgc cgtcggggcc ggtgagccgg atgacgccgt cggccgggag caccggtccg
     8521 tcggtgtcgg tgacctcggt catctcccag atctccgggt gcccgcccgc gcccttggtg
     8581 gcgggcgggg tgagcacgac cagccggtgg ccgtgcggca ggtcgtgggt gagccggcgg
     8641 aaggagccgg acaggacctc gggcagttcg aaggtgtcgt gctcggcggc cttacggacc
     8701 cggaactcca tgaccgccgg acagcgcacg tcaccggccg ggtcgggcac gcccgccggc
     8761 tggtcagggc ccttgttgac cagccgcagg gtgcggccgg ccagccgccg gaagtccacc
     8821 agcaggtcga agcgctcggc gggcgccgcg gtcagggtgg gcagttccgc gccgaagtcc
     8881 accggcacgg gccgcggcag cagccctccg tcgctgccga tctggtgcac gatgccgggc
     8941 accggatcgc cgtcctcgtc gatcaggacc aggtcgaaga tgcgcgcgtt cgaggcgttg
     9001 accaggcgga agcggtacca ggccgagtcc acctcggcgt acggccagat gcggccgttg
     9061 accgtggtgt agggcccgct gaacgggatg gtcaccggct tgccggtctc cgggtcgctc
     9121 tgctgtacga cgaccgtctt gtgcagcagc cgcccgttga gccgcccgtc ctcgtcggtg
     9181 tcgagattgc ggtcggcgag cagcagcggg atctcccgct ccccggacgg cagatggagg
     9241 gcgtcctcct cgtcgtcgcg gacgaggtag gtgccgtaga gcccggacat cacgttccag
     9301 cgggtgatgt tcatggcgtg gtcgtggtac caccactgcg tcgcctgatg gtcgttcggg
     9361 tattcggaca gctgggcgtc gcctgagccg accgcgttgt ccgcccagcc gtcattgccg
     9421 ccgccggtct gggcaccgtg cagatgggtc accgtccagg cgggcagggc ggcgacgtcc
     9481 ttgtcgggtt cggcgccgcc gcggccgggc tcggtggtgg cgggcgcggc gccgggcgcc
     9541 cggaccggta ccgccaccgc ggtcaccggg tactcggcgt ccttggggat gcggttggtc
     9601 caggcgatac ggatacggcg gccgcgccgc acctcgatgg tcgggccggg gacatggccg
     9661 tcgtagcccc acatcagggt gggcggcagc tgcgggtgca gccgcaccca ggtcgggcgc
     9721 agggcgatct cggtctcctg ccggacgtcg gccgaggtcg gccgcagcac cggcggcacg
     9781 gtcaacggcg cgacatacgg ccgcagttcg cccggcgccc gcttcttctc ccccgtggcg
     9841 ccggtgatcc tctcgacagc cttctcgatg atctcggtca agctcgaaca ccccccgtgt
     9901 tctcgcgtgg tgtcgttccc cttgactgtg aagaccgcga agagtccgcc gaatttccct
     9961 gaatgcccta ctccgtacga gtagattccg aaacggccga tcagcccgga gtgagcagcg
    10021 gtcgcacggg cgggcggtcg ggcaggaagc catgggcgcg ccgtgacagc caggcgtcct
    10081 tgtaacggtc cacgctgcgg tgccagttga ggattcccgc gagccagttc cgcaggtcgt
    10141 cgacgtagcc gtccaccgcc gcccgggcct gcggggacag cccgaagtcc tcgtacagca
    10201 ccggcagttc atgggcggcc acatgttcga actgccgcat gcgctgggtg gtcaggtcgt
    10261 ggacgacgcc gagcgcggtc gggtagtcga cgccgaagaa gttctgcacg accaggacgg
    10321 cgttgtggat ctcgccctcg tactcgatct ccttctggta cgagaagatg tcgttgagca
    10381 ggcaggcgta gtcgatggcg gcgttctcca gggagcgcac cgggccgctg cggtagacct
    10441 ccggcgggac cgcggggccc cggcccatcc ggcacaggct cagggtgagg tcggagccga
    10501 aggtggcgcg gcgcatctcc aggtagtcga ccgggtcggg aatgcggttc tggagctggt
    10561 tggacagctc ccacacccag ctctcggtca tggtgtccac ggcggccttg agggtgcgcc
    10621 gctgcccggt gctcatcgcg gcggtggtgc gggcccacag gtcgatcagg gagcgttcca
    10681 tggcgttgcc gggcaccagc gggggctcgc cgtcgacggg catgcaggcc gacagccggg
    10741 cggtggtgag gcgggcggcg gccaggtccc tgcggtggcc gtagaccagc gggtagtagt
    10801 cgtcgccgta ggtgccgaag gcgagccact gggcgctgag gtcgagggcc tcgggggtgg
    10861 cgtcggggtc gaggccggcg gagcacaggg cgagatcgta ggcgcgcagt ttgtcctcgt
    10921 cccagacgcc ctcctggagg atgcccacct ggtcgcacca ggcgcgcaga ttgcggcggg
    10981 tggcgtcgag gtgcgggctg agctccaggg cgaacggcat gtggaactcg ggcaggatcg
    11041 aggggccgac cttctggtgg ggcacatgcg agtaggcgcg cagccgctcg tgcgcggcgg
    11101 aggcgagcag ggcgccgatc cgggcggcgg aggtgccggg gccgctgggc agcatccagg
    11161 gcgagtcgtt tcgcgcgccc ttgttcatat agcggctgga gcgcagatgc cattcgtggc
    11221 cgccgctctg ccagtcctgg agtcccttgg cgtaggcggc gatcgcgccc gtctcggccg
    11281 gggtgaggcg gtgttccagg gcgatcgcgg gcacctcggt gagcgcggtg tgctcgaact
    11341 ggtgcaggcg tgaggtgagg atgtcgttga cggtgtcggc ggcctgctgg gtggtgcagc
    11401 cgaagaaggt ctccaggacg agcacgccgt tgctgttctc gccctcgtcc tcgacctcgc
    11461 gctggtagga gaacaggtcg ttgcgcagat ggacggcgtc ggcgaaggtc tccatgagca
    11521 cccgcagcgg cctggtctcc gcgacggagg cgggcacctc ggcggtcgcg tactccacga
    11581 gcccggcgga ccagggcgcg ccgcccacct tgcggcgcat ctcgatgtac tcgacggggt
    11641 tggcgatccg tccctcgttg atgttggaca gctcccacat cgactcgttg agcagatgct
    11701 cggtggccac cgagaagcgg cggcgccagt ccaccgacat cgcgggcacc gtacgcgccc
    11761 acaggtcctt caaacccgcc tcgacggggt tctccggctc gggcacgggg gtcgcgggat
    11821 cgatgggcat gaacagcggg agccggtcga ggtgggcctt gccggcggcg cggtcctggg
    11881 tccgcttgaa catgtccagg aagtggtcgt cgaagaagaa cacccatacg taccagtcgg
    11941 tgatcagcga gagggcggcg ccgtcgcagt cggggtgggt gtaggcgcac agcagcccgt
    12001 agtcgtgcgc gtccaggtcg gcctggtccc agatcccgga gccctccagc atgcccatct
    12061 cgcgcgccca cgcggtggaa tgggagcgtg cctcgtcgag gtgcggattg agccgcgcgg
    12121 gaaacggcat gtagaagtgc gggagttcga acggctgcgt catggccggg ccctacccgg
    12181 ggctccgaac acccatccca cgcgcgggac atgatcacac catcgcgtga accacccccg
    12241 gggtgtgccc cgtccgcgcc cttgccgtgc tcgggccccc gggccacggt aggcgcatga
    12301 actccttcgt gctgccccat gaggtgcacg gcgacggcgc ccaccgggtg ttcgccgtac
    12361 acggctggtt cgccgaccgc tccgcctacg cggccgtcct cccggacctg gaccgcacct
    12421 ccttcaccta tgtgccggtc gatctgcgcg gctacgggga ggccgcggac gcgccggggc
    12481 cgtacacgac ggctcaggcg gccgtggacc tggtggcgct ggccgaccgg ctcggctggg
    12541 ccaggttctc ggtgatcggg cactccatgg gcggcgcggt ggcccagcgg ctgctcgcgc
    12601 tcgcccccga gcggctgcgc cggatcgtcg gggtctcccc ggtacccgcc gcggggatgc
    12661 cgctctcggg cgagcagggc gcgctgttca tggacgcggc gcacaaggcg ggcaaccggc
    12721 gcgcgatcat cgacttcacc accggtggcc gccgtccggc cgcctggctg gaccggatgg
    12781 tgtggacgtc gttccagcgc agcgacgcga aggcgttccg ggcctggctg gactcctggg
    12841 cgggcgagga cttccacgcc gaggtgaccg gcagcgaggt gcccgcgctg gccgtggcgg
    12901 gcgaactgga cccggccctg tcgcccgacc tgatgcgtca gacctggctg tcctggtacc
    12961 ggcacggcga tctcgtcgcg ctgcccgggg ccgggcacta cgcgatggac gagacaccgc
    13021 tggagctgat ccgggtggtg gaggacttcc tgcgcgcgga cgggagcgac cgggcgtgag
    13081 caccggaacc accgctccgg tgccggacgt cttcgacccg cgccggtacg cctgcggggt
    13141 gccgtacgac gcctaccgcg tcctgcgcga cgcgcacccg gtggcctggc aggaggaacc
    13201 cgaggtgctg ggctggcccg cgggtcccgg gttctgggcc gtgacccggc acgcggacgt
    13261 cgtccgggtc ctgaaggact cggccgggta ctcctcgcac ctcggcgcga cccagatccg
    13321 ggacccggac ccggaggacc tgccgttcgt gcggcgcatg atgctcaatc aggacccgcc
    13381 ccgccacggc cggttgcggc ggctggtgag ccgggcgttc accccggggc ggatcgagcg
    13441 gttcgcggcc ctcgcccggg agcgggcgcg gaccctgctc gcgacggcac gggagcgggc
    13501 cgggcggggg gacggcacgg tcgatctggt gacggccgtc accgacgagt acgccctgct
    13561 caacctcacc gacctgctgg gcgtcccgga cggcgaccgc cggctgctgc tgcactggac
    13621 gcggcgggtg atcggctacc aggacccgga cgaggccgct cccccggttc tcgacggctc
    13681 gggcaagccg ctgaacccgc gctccccggc gatgctgcgg gacatgttcg gctacgcgca
    13741 cgaactggcc gcgcacaaac gccggcaccc cgccgacgac atcatgacga ccctcgccac
    13801 cgaccccgaa ctcaccgggc ccgagctgga gatgttcttc ttcctgctca cggtcgcggg
    13861 caacgacacc gtgcgcagcg cggccccggg cggcctgcag gccctggccg aacacccgcg
    13921 gtcgtacgat ctgctgcgca ccggcaaggc cgaactcgcc ccggccgttg atgagttgct
    13981 gcgctggcat ccgcccgtgc tgaccttccg gcgcaccgcc gcgcaggaca ccgagctggc
    14041 gggccggcgc atcccggcgg gcgacaaggt cgtggtcttc cacgcctccg ccaaccgcga
    14101 cgagcgggcc ttcgccgacc ccggccggct ggacctcgcc cgctccccca acccgcatgt
    14161 ctccttcggg gacggcccgc acgtctgcct gggcgcccac ttcgcccgcc tgcaactgcg
    14221 gctgctctac gcggaggtgg cgcgcgccct gcccgaactg cgccccgcgg gcccggccga
    14281 gcggctggtg tccaacttca tcaacgggct caagtccctt cccgtacagg tcggttgacc
    14341 tggatcagcg catgtgtgcc gtccgtgcgc cagcgctgcc cctccgccgc caccagccgc
    14401 gcctcggtgg cggcggtcag cccggtgatc acctcggact tcagagtgcg cagcgcggcc
    14461 accggaccgg ggaagtacgc ggtcgccgcc gcgaaggacg tggtgggcgg ccggcgtcga
    14521 tcccccacca gacggcggta gttgaggtcg cccttgaaaa gggtgaggcc ggcggcggcg
    14581 aactcggcac gcaggtccgg cggcatccgc tcgtacggca gcggggcgca gaagaagggg
    14641 tgggcgcgga ccgtgagccg cccgtcggcc atggcggagc ggagcagccg ccccagctca
    14701 ccggccgcgc ccggcgccgt acgcagccgt tccaggccgt cgagcacatc ggccatgatc
    14761 gcgtccgaga cgtagtacgg gtacggcttc acctggagca ccgcccgcgc gatccggccc
    14821 ccggcgagca gatgggcgat cagcagcagg tcggggacga gttcacggcc ggcgttgtcc
    14881 gcgacgagga ccaggtcggc tccgccgccg ggcggcagca gcgaccacag ccgctcgctg
    14941 tcgtcggcga ccagcgcggg tgccggctcc cgggcctcgg cgccctcggc ggacagccgg
    15001 aaccccaggt cggcgcggtt gccccagagc gagccgtgca gcagggcgcg gccccgctcg
    15061 ggctccggaa ggtcccgcag gtcgtcgagg gcggcgagtt cccggtcggt ctccggcgcg
    15121 tccagttccg cgcgcttgac gggccggaag gggtcgatgc cccgccaggg cccgggcgtg
    15181 aagtagccga cggcttcgag gagtcggcgg tagaagtagc tctcggacca cagccacggc
    15241 acatcgaacc aggactgccc ggcgtactcg gccaggcccc acgcgtgcca ggccgcgcgg
    15301 tccggggcgt cggcgggcag gggtgccacg gtcccctcgg cgcagctctt cagcagctcg
    15361 tccagcgccc ggtgctgccc ggggccgtac gggaaggcgt cccgcacctg gcggatgatc
    15421 gccgggtgcc gctcggccag cacaccgtgc gggaacgagc cgggttcgtt gccgagaatc
    15481 acggatgcga acggggtttc gggcatgtcc gtcaccgtac cgcgcgtctc aggcggttct
    15541 gatctcccgc tccagctgcg tggcgagggt gacgtagcgg gggcggcggt gcaccgggac
    15601 caggccgcgg atcatcaggt gccacatctc ggcgacccgg cgcggcaggc gtcccacggg
    15661 ttcgaagcgg ccggcgacgc gggtgccgaa gaagaagcag acgagcgagt gggcggcggc
    15721 ggagacatcc aggtcgccgt gcacatcggc ctcgcgcacg gccccggtga acttgcgggc
    15781 ggcgaactcc agccattcgg tgtaggggtg gcgcagcggc ggccgtacgg tgacgtcggc
    15841 ggtggccagg cgcagtccgg cgcgcggcac cgggtcgtcc acggcgagcc gggcgatccc
    15901 gaaggtggtg cgcatcaggc cctccaggga ggagtagccg cggccgtcga gatcggccac
    15961 cagacggcgg gccgcgcggt tctccagctc caggatcgcg tgcgccaggt cctcctttgc
    16021 ggcgaagtgg aagtagaggg cgcccttggt gaccttcgcg tgtgcgacga tgtcgctcag
    16081 actggtggac tcgtagccgt gttggtcgaa cagatcggcg gcggccgtga tgatcgtggc
    16141 ccgggtctgt tcggcgcgta actgcctcgc catgctggga cccctcctcg cgagacgaac
    16201 gaacgggaca tgcggtttgt ttttaacccc ttgcatacga taactcaccg aatgacaacg
    16261 ggagtcccca tgatcgccac gatacgaggc ggacacccgg ctcctcaacg gcgtctcacc
    16321 ggagggccga aaaagaccaa ctgccttgcg ctgtaaggca gtacggctct cccggcggga
    16381 ccgcgcacag cagggcggcg ccgccgcgat gccggagtgc accgcgtcgg cgccgcctgg
    16441 gcgctgcgtt caggacggcc cgaaacgacc gctcgggaga cgtcagttga cgtagaccga
    16501 tgccccgccg tcggtcaccg gtgcgtactt ggcactgaag tacgcggtgg agaagcagag
    16561 cgaggacccg gaggtcttgg tgaactgctg gttggtgaag gtgatgctgt tgtcggcgtt
    16621 ggccgtcttc ccggccaggc tcgggccctg gtagacacag gtgacgctgc ccagcagggt
    16681 gctcagcttg accgtggact ggatgacgga gccgctcggg ggcgtgacgg tgagggtgcc
    16741 ggcggaggct gccgccgccg tgtagggcag gttgtcgatg gtcacgccgg agacgccgag
    16801 gacaccggtg acattgctgg tgcagccgct gaaggtctgc ccggtgaggg actcggtggc
    16861 ggtgcccggc gcggtcgggt tggcggtgac cttggcggtg aactgggagg tgccgcactt
    16921 cacgccgctg gtgccggtcg agctggagta gaaggtggcc gaggtgccgc tcgccagggg
    16981 cgcggtgagg gtgtcgccga ccgcgacggc ggtgccgccg gcgctgcccg tggtgaggac
    17041 cgtgccggcc gcggaggccg gaccggccga cacgagggcg agcacggtgg cgctggcggt
    17101 ggcggcgaga gcgatgaggg tacgcgtacg catgcgggtg cctctctgat ggggtgggga
    17161 aacgcggacg tggggggtgg gggcggtgcg cggcggtgcg gatgtcgccg ccggcgcggg
    17221 cccgtcacgc cttctcctta cgcgacggac cggcgacggc ggcgggccgg acaccggccg
    17281 gtacccgggg ggaatcggcc gggccggacg aacagggggg gtgccggtac ggacccgtgc
    17341 gggagctgtc cgtgccgtac tcgcgcgacg tgcgggaaga tcaccgtgcg ggaagatcac
    17401 cgttcgggac ggccgccgtt cgaaggggcc gatatgtgcg acggcccgcg ttcgagacga
    17461 tcgccgcgca gtggagcggg tgccgcgtaa gggccgggaa cgcggccggt gcccgcaggg
    17521 gacacggccg ctgccgctcg ggggatccgg cgccacggat ccgtggaatc tgaggaattt
    17581 gtagccccgt caaccatcgg cgtcaaccca tcggaccgtt caacacatct gtacacaggg
    17641 gaagttgagg gttcgcaggg cgcgcacgca ccgtcgacac ccttttttca catctccctt
    17701 gaccccaaaa tgtaaccggc ggtaacttcc tcgaaaggct accgccgcgt aacgagaaag
    17761 cccttgcacc cgccgggagt gcgaggaggc gtccgcggcg gccgctgtcc gcgccaggac
    17821 atcgcgccac tgaagcccaa cccgcattga tccatgccca tgggagcaga catggcctcg
    17881 tccccggacc tctcgtccac cggcaacacc cccgagaacc cggaaagcgg ttcaccgtcc
    17941 gaagcaccga gcggcaccgc ggcccccgcg gccggcagac ggggccgcgt ccgggcccgt
    18001 cgcgccgcgg tgatggcggt gcccgccacc ctcgtcgccg ccggcctcgc ggtcctcacc
    18061 gcgcagggcg cgctcggtgt gcagttctcc atctccggca tgccgttcac ggtcgccgcg
    18121 agccagctgg acggcaccgg cttcgaacag ttcggcggcc tggacaacat ggccgacggc
    18181 agccccaacg ccggtgacac cggcggccag gtgctcatcg tcacctcggc gatcaagaaa
    18241 gccaccctga ccaagctgtg ccagagcgtc gacctcggcg gcaccaacct gctgatcacc
    18301 gcgggcggcg gcgacaccaa ggtcagcgcg tccgatctga ccaccgactc caccgagatg
    18361 tcgggtgacg cctcgttcaa ccacatcgag atcggcaacg acgcgagcac gctgaccgag
    18421 gccaacgcga agggcccgat cggcgtcttc agccagcagg ccgacagcgt gcacatcgac
    18481 aatctgcggc agaccaacta cgcgaccacg gcaggggtgt tcaagctgcc gggtctcaag
    18541 ctgcgcttca gcgactcggg ttgctgagcg ccgtggagga gagtccccga ccggttcccc
    18601 ggcgctcctt ccgggcctgg cgggcccgcc ggccgttctg gggcgggctg ctgctcgccc
    18661 tgggcggcgg cgagatcctg ctgaccgaga aggcgtcact gaaggtcgtg atgcacatcg
    18721 gcatgcaggg gctcgccggc tatctgctgc cggtcctgat ggcgctgctg ggcctgctgg
    18781 tcctcttcaa ccccacccag cggctcttct actccatcct cggggtgctg gcatcgctgg
    18841 gcacctgggt cacgtccaac ctgggcggct tcttcatcgg cctgctgctc ggtgtcgtcg
    18901 gcagctgtct cgccttcggc tggctgccgg accaggagcc ccgggtgagc cgccgcaagc
    18961 gccgccgccg ggcacgggcc ctcgccgagg aggccgggac gagcgccgtg tgacgtcccg
    19021 gaactttccg gccccaccgt cagtttctac ggtgttgtag aagttgccgg tgggtgccgc
    19081 ggggcacctg ccgttgatat gaggagcgag catggccctg tgggaccgcg tcaaggaatc
    19141 cgcgtcgcag atgcagaacc agttggtggc gaagaagaac gacctgaaga gcggcgcctt
    19201 ccgggacgcg agcatggcca tgtgcgccct ggtggccgcc gcggacggca ccgtcgaccc
    19261 ctcggagcgc cagcgcgtgg cccagctcat cgccaccaat gaggtgctcc agaacttccc
    19321 ggcggacgac ctgcgccgcc gcttcgagga caatctgaac aagctcacca ccgacttcgc
    19381 cttcggcaag gtgagcgtcc tccaggagat cgccaaggcc aagaagaagc ccgccgaggc
    19441 ccgcgccgtc atccagatcg gcatcgtcat cggcggcgcc gacggcgact tcgacaagac
    19501 cgagcagtcc gtcgtccgcg aggcctgctt caccctggaa ctcccgccgc acgagttcga
    19561 cctctgaccg acgcgacggg gcgggggcgc gaccggagaa ctccggccgc gcccccgccc
    19621 acgcccccgt cagctcaccg gctgaagctt gtaggtgaag gtggactgcc caccgcagtc
    19681 ggccgggcct ccggtgcgac cgaggctgaa gtaggaccag aaggtgatcg tggacttgcc
    19741 gtccagcggc accgtcttgt tgatcgcgta cgtctcgctg cggtcgcggg tgtcgccggg
    19801 cacatcgccc gaagccacct tggaccacac cgagctgttg ttgccccgca acaggtactg
    19861 ctcgcccacg tacgaggtga cgcccgcccg gtagaacacc tggatgctct tgaccacgat
    19921 gctggtcttc gtgacgttcc cgagcgtcca ggtcgcgtgc ccctggatcc aggcgttgct
    19981 gaggcagccc gacagggtgc tctgatccag ttcggtgtgg ccggtgtaca ccgtcctcgt
    20041 accgctgccc accgtcacct tgttgacgaa gccgggaatg tcctcggcct gggccgcacc
    20101 ggtgctcatc accatggcga gagtcgcggt acccgcggcc agcgcggccg acagggctcg
    20161 tctcttcatc atccgttccc ccatgttccg tgtcgcgccc acctgcctgc gggccgcctt
    20221 cgcccacacg ctacggtcgc tcgccggggg ccgccttgac cgtgcatccc ctccccttga
    20281 cgccgcgtct catcctgcga cgcggcccac cgacggtgac actcaggagg acggcagcat
    20341 ggcgcacggc gacttcggaa cccggcacct gaaggcggcg gagcgactgg ccgcggcgga
    20401 cgagctgttc ggccggggcc tgctgccgat gcggctcctg aaccgggccg gcgacacgtt
    20461 cgaggcgtcc gtgcggcatg tggacctcgc cccgctgacg gtcgtgaagt tctcggcgac
    20521 acccgccgcc gtactgcgca ctccgcggtt gatccgccgc ggcgacccgg agatgctctc
    20581 gctcatcgtc ccggtggacg ccggcctgac cgtgggccag gtcgggcggg agaccgtcgt
    20641 ccgcgccgac gagatggcgc tgtacgacag ttcgcagccg ttccggatcc aggtgacggc
    20701 ggagtcggcc gtaccgggcg tcaccacggt cgtctccctc cacgcgcccc gcgctctgct
    20761 ggggctgccg cccggcggac tcgaccccct gctggcacgg ccgttgccgg cgggccgggg
    20821 cgcgctcttc ggccggacgc tccatcagat cctgagcgat gtgatcgagg acggcaccgg
    20881 acaccggccg gtcgacctcg cccgcctggg gcacgtcgcc ctcgatctgg tgaccgcgct
    20941 ggtcgcccat cacctggagg ccgaggccct cgtaccggag agcgtccagc accgcacgct
    21001 gctgctgcgc gtcgactcct tcatccggca gcggttgcac gacgtgacgc tgtccccggc
    21061 cacggtcgcc gccgcgcacc acatctcggt cagccatctg caccgcctgt tcgaaccccg
    21121 ccggaccacc gtggccgcct cgatccggcg gcagcgcctg gaacgcgcac gccgcgacct
    21181 cgccgacccg gcgctgcgcg acatgccggt ccatcgcatc gcggaccgct ggggcttcag
    21241 gggacactcc actttcaccc gggcgttccg cgccgcgttc gggacctcgc cgcaggacta
    21301 ccgcaacagc gccctcgcgg cggccgcgga cgagcggcgc tgggacgggg cgtgccgtga
    21361 ggcttcctgg tcctgccagg agaacagcag gtcctcgatg ccgagggact cacggccgcc
    21421 gtgggagtag ccgcccagac cggtcacccg gaccgggccg gtccctcgtc gatcagcgct
    21481 tcgcctcgga cgtcggcgcc tcgtcgaggc ggccgcggat ccgcttcggg tccgacagga
    21541 gcgaccgggc caggtacgcg ccaccgcgat cggggccggc caggaccgcc acgaccccgt
    21601 accgcgtgac caacgcgtcc agaccggcct cgccgacccc caccggtccg gccgcgggga
    21661 cggggtcggc gagaccgggt gggacgggtc cgtccgtcag gcgagccccg ccgacttcag
    21721 ccacgccttc gccacgtcca gcgggtcctt gtgctggagc tggacctggg tgtccaggtc
    21781 gagcagggtc gtggtgtcga gtttggcgga gaccgcgttc agggcggcga cgcccttctt
    21841 ggggagggcg gtcttggaga cgacgggctg gacgttctgg aagccgaaga ggttctgggg
    21901 gtcctggagg acgacgaact tctccttggc gatggtgggg tcggtgctga agatgtcggc
    21961 gacctggacg tcgttcttct tcagcgcggt ctgggtgagc gtgccgcccg cgtccagcgc
    22021 cttgaaggac ttgaagtcca ggccgtagac ggacttcagg cccaccaggc cctgctgccg
    22081 ggtctggaac tccggggagc ccccgatcac caggcccccc gcgacggcct tcagatcggc
    22141 ggcgctggac cgcgcggtga ggt
//
