LOCUS       NZ_CP094483            22679 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces murinus strain JS029 chromosome.
ACCESSION   NZ_CP094483
VERSION     NZ_CP094483.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces murinus
  ORGANISM  Streptomyces murinus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Draft genome sequence of Streptomyces sp. JS029
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAR-2022) Agricultural Life Science, Sunchon National
            University, Jungangro 255, Suncheon, Jeonnam 57922, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-MAR-2021
            Assembly Method                   :: Unicycler v. 0.3.1
            Assembly Name                     :: JS029
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 164.82x
            Sequencing Technology             :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028753175.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 03:30:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,582
            CDSs (total)                      :: 7,481
            Genes (coding)                    :: 7,273
            CDSs (with protein)               :: 7,273
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 215
            CDSs (without protein)            :: 208
            Pseudo Genes (ambiguous residues) :: 0 of 215
            Pseudo Genes (frameshifted)       :: 110 of 215
            Pseudo Genes (incomplete)         :: 125 of 215
            Pseudo Genes (internal stop)      :: 20 of 215
            Pseudo Genes (multiple problems)  :: 41 of 215
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:08:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 826841
            Orig. end                         :: 849520
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP094483.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from National Institute of
            Biological Resources.
FEATURES             Location/Qualifiers
     region          1..22679
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="9"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22679
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22679
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12679](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12679)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(65..79)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.0"
                     /tool="antismash"
     gene            complement(342..1256)
                     /gene="mmsB"
                     /locus_tag="ME763_RS03485"
                     /old_locus_tag="ME763_03490"
     CDS             complement(342..1256)
                     /EC_number="1.1.1.31"
                     /GO_function="GO:0008442 - 3-hydroxyisobutyrate
                     dehydrogenase activity [Evidence IEA]"
                     /GO_process="GO:0006574 - valine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mmsB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018100009.1"
                     /locus_tag="ME763_RS03485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03490"
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="WP_274506033.1"
                     /transl_table=11
                     /translation="MSGDGGARRTVAFIGLGHMGGPMAANLVEAGHRVRGHDLVPEALA
                     AAVRAGVEPAGSAAEAVADADTVLTMLPAGRHVLDLYDTLLPAARPGTLFVDCSTIDVA
                     DARTAHERAVAAGMRALDAPVSGGVVGAEAGTLTFMAGGGEAEFAGARPLLDVMGGKAV
                     HCGGPGAGQAAKICNNMILGVSMIAVSEAFVLGERLGLSHQALFDVASTASGQCWALSV
                     NCPVPGPVPTSPANRDYRPGFAAALMAKDLGLAANAVKAGGVQAELGLRAAELYAEYAE
                     RVGAAEDFSGIVRTIREQSGERA"
     gene            complement(1253..2332)
                     /locus_tag="ME763_RS03490"
                     /old_locus_tag="ME763_03495"
     CDS             complement(1253..2332)
                     /NRPS_PKS="Domain: ECH (11-199). E-value: 4.8e-33. Score:
                     106.4. Matches aSDomain:
                     nrpspksdomains_ME763_RS03490_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003952870.1"
                     /locus_tag="ME763_RS03490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03495"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_085567774.1"
                     /transl_table=11
                     /translation="MSNDTEEPVLLRTEGRAARIILNRPRALNALTHEMVTRIDAALTD
                     WEHDPAVRTVVISGAGARGLCAGGDIRAIHDDARAGDGTASAAFWRDEYHLNARTARYP
                     KPYVALMDGIVMGGGVGVSAHGGVRVVTERSRIAMPETGIGFIPDVGGTYLLSRAPGEL
                     GTHLALTGNQIGAGDALLCGLADHYVPSDALDALLADLAALPVAEALARHEQPAPKGVL
                     TEQRSWIDACCSADSVEEIVERLFAHGGTEAKEAAETLLAKSPTALKVTLAALRRARRL
                     GTLEEVLDQEYRVSCVGLRSPDLVEGVRAQIIDKDRDPHWSPATLAEVGDADVERFFAP
                     LGDRELGLAGPGGTTEAAR"
     aSDomain        complement(1736..2299)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ME763_RS03490_ECH.1"
                     /evalue="4.80E-33"
                     /label="ME763_RS03490_ECH.1"
                     /locus_tag="ME763_RS03490"
                     /protein_end="199"
                     /protein_start="11"
                     /score="106.4"
                     /tool="antismash"
                     /translation="RTEGRAARIILNRPRALNALTHEMVTRIDAALTDWEHDPAVRTVV
                     ISGAGARGLCAGGDIRAIHDDARAGDGTASAAFWRDEYHLNARTARYPKPYVALMDGIV
                     MGGGVGVSAHGGVRVVTERSRIAMPETGIGFIPDVGGTYLLSRAPGELGTHLALTGNQI
                     GAGDALLCGLADHYVPSDALDALLA"
     gene            complement(2329..3477)
                     /locus_tag="ME763_RS03495"
                     /old_locus_tag="ME763_03500"
     CDS             complement(2329..3477)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003952871.1"
                     /locus_tag="ME763_RS03495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03500"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_085567773.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.6e-26, bitscore:
                     91.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.8e-26, bitscore:
                     90.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.4e-47, bitscore:
                     160.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTLLTEDQRALVETTLDFAQDHLAPHALDWDRDRHFPVDVLRK
                     AAGLGLGGVYVREQHGGSALGRADGVLVFEALASGCPAIAGYLSIHNMVAWMIDHYGDD
                     AQRERRLPRLCAMDDLASYCLTEPGAGSDAAALTTRAVPDGDHYVLTGVKQFISGAGAA
                     QVYVVMARTGEPGPRGISAFLVDKDDPGISFGPNERKMGWHAQPTRQVVLDGVRIPADR
                     LLGRAGEGFRIAMNGLNGGRLGIAACSLGGARSALDRSLAHLADREAFGARLLDAQALR
                     FRLADMATELTAARALVQQAARALDAGDPQAPYLCAMAKRFATDTGYSVADRALQLHGG
                     YGYLAEYGIEKIVRDLRVHQILEGTNEIMRVIVARGLTEALG"
     gene            complement(3485..5008)
                     /locus_tag="ME763_RS03500"
                     /old_locus_tag="ME763_03505"
     CDS             complement(3485..5008)
                     /EC_number="1.2.1.-"
                     /GO_function="GO:0018478 - malonate-semialdehyde
                     dehydrogenase (acetylating) activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963374.1"
                     /locus_tag="ME763_RS03500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03505"
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="WP_085567772.1"
                     /sec_met_domain="Aldedh (E-value: 6.5e-136, bitscore:
                     452.2, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRPQAPSAVRELTHFVDGEHFLGTSGAHGEVYDPNTGEVQALVP
                     LADRGETTAAITSAAEAQRAWAEWNPQRRARVLLRFLQLAEQEKDALARLLSAEHGKTV
                     ADAHGDLQRGLDVVEFAAGIPHLLKGEFSDNAGTGIDVHSLRAPLGVIAGITPFNFPAM
                     IPLWQAAPALACGNAFVLKPSERNPSVPLRLAELFLEAGLPPGVLNVVNGARDAVDTLL
                     EDPRVAALGFVGSTPIAAHVYATAAAHGKRAQCFGGAKNHLIVMPDADLDQTVDALIGA
                     GYGSAGERCMAISVAVPVGAATADALVARLTERIAALRIGRSDDPEADFGPLVAPEALR
                     RVREYVDLGVQEGAELIVDGRDFVLPGHEKGFFAGASLFDRVTPDMRIYQEEIFGPVLS
                     VVRAADYEEALRLPSEHRYGNGVAIFTRDGDTARDFTRRVNTGMVGVNVPIPVPVAHHT
                     FGGWKRSGFGDLGQHGPDAIRFCTRTKTVTSRWPAGRREGASFTIPTMG"
     regulatory      complement(5262..5390)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(5264..5281)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 18.77"
                     /tool="antismash"
     gene            complement(5469..6314)
                     /locus_tag="ME763_RS03505"
                     /old_locus_tag="ME763_03510"
     CDS             complement(5469..6314)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018548572.1"
                     /locus_tag="ME763_RS03505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03510"
                     /product="ECF transporter S component"
                     /protein_id="WP_085567771.1"
                     /transl_table=11
                     /translation="MSGRAGAGGPAIRLTGRAAVVMALAALLGLVAFFWPFVVAPGTFG
                     SSYAPPLIFGVLLVLVLCVVLSEIAEGGIDSKALAMLGVLSAVDAALRPLGAGTAGIET
                     VFFVLVLAGRVYGPGFGFVLGCTSLFASALITGGVGPWMPYQMFGCAFVGMLAGFLPRA
                     SGRREVLMLAVYGSLSGYLFGFLLNLSFWPFSLDPNSSIAYLPGLPFTEQWHRYVAFDL
                     ATSLGWDTGRAVTNFVCVLLAGPAVLTTFRRAARRARFRAPVRFAEPRKRPARGADGVA
                     "
     gene            complement(6311..7951)
                     /locus_tag="ME763_RS03510"
                     /old_locus_tag="ME763_03515"
     CDS             complement(6311..7951)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173864.1"
                     /locus_tag="ME763_RS03510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03515"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_085567770.1"
                     /transl_table=11
                     /translation="MITFDQVTVHYDDMPEPALRDVALTVDEGELCLVTGHTGVGKSTL
                     LGAVNGLVPHFTGGTLYGRVTVDGRDTAHHPPRELADVVGVVGQDPIDGFVTDTVEEEL
                     AYAMEQLAIPPATMRKRVEETLDLLGLADLRHRALHTLSGGQQQRVAIGSVLTAHPRVL
                     VLDEPTSALDPTAAEEVLAAVTRLVHDLGVTVLMAEHRLERVVQYADRVIHLPGDGRAR
                     IGPPAEILRTATIAPPIVELGRAAGWSPLPLSIRDARRAAAPLRARLAERTPAPVRPPV
                     PGGGGNRLLAARGVTVAYRDLAAVRAVDLDLHAGEVVALMGRNGSGKSSLLWALQGSGP
                     RRAGSVRVHGEHGVKDPHTVSAAEARRLVGLVPQTPADLLYLESVGQELAQADAESAAG
                     VTARELLDRLAPGIEDATHPRDLSEGQKLALVLAVQLAAAPRVVLLDEPTRGLDYRAKT
                     ALTAIVDALAAEGRAVVISTHDVEFAARAADRVVVMAEGDIVADGPTTEVIVSSPTFAP
                     QTAKILAPLPFLTVDQVARALADTDEARS"
     gene            complement(7948..9108)
                     /locus_tag="ME763_RS03515"
                     /old_locus_tag="ME763_03520"
     CDS             complement(7948..9108)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173863.1"
                     /locus_tag="ME763_RS03515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03520"
                     /product="CbiQ family ECF transporter T component"
                     /protein_id="WP_085567769.1"
                     /transl_table=11
                     /translation="MTAVSRTAVEAPAAAAAPDRGGRRLPRTLHPMAWWVWALALATAV
                     SRTDNPLLLLLVLAVLGYVVTARRTEAPWARGFVYYLYLALSVVAIRVVFRAVFATGIT
                     PHDHFLFSLPHLPTPDWYAGIQIGGPVSLEALLSSATDGLRLACMLACVGAANTLANPK
                     RALRVLPGALYELGVAVTVAISVAPQLVQSVQRVARARRLRAGRAKGVKALRAIAVPVL
                     EDALERSLRLAAAMDSRGYGRAGSATRRSRRITGALMLLGMCGLCAGAYGLLDATAPTL
                     LGLPAMTCGAALCVAGLRLGGRRVTRTAYRPDPWRLPEWCVAGSGVLSAVLLFSDLGYD
                     PAQLNPTYYPLTWPGLPLVPTAAVLLAGTAGFLAPPPGPVPRATAP"
     gene            complement(9105..10004)
                     /locus_tag="ME763_RS03520"
                     /old_locus_tag="ME763_03525"
     CDS             complement(9105..10004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018100021.1"
                     /locus_tag="ME763_RS03520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03525"
                     /product="hypothetical protein"
                     /protein_id="WP_085567768.1"
                     /transl_table=11
                     /translation="MRAVARPIRALAALGLGAAAVVQTGTPAAADPQPMGRCTTSSGVV
                     LAVDLSHWGGPILRSCGTTPTTGYELLNQGGWSTTGTGHDGPAFICRIGYSGYQHGRQY
                     PTPAQDDCVLTPPASAYWSYWHADPGATDWTYSQLGAMLYKPEPGSVDLWEFGGTNIQG
                     TEGRPKVTPDQLRAHNTAPQGDAGKPASTRKAPELPPGVNTGPAPEKQPAPSALPSTKP
                     KPSRSASPSPSPSTTTSAPAAPPPPPSPSTGTRVVDAAPAAEARHDAGSIVPVAAGAGL
                     VVLIGGAAYAAHRRRRSE"
     gene            complement(10001..12679)
                     /locus_tag="ME763_RS03525"
                     /old_locus_tag="ME763_03530"
     CDS             complement(10001..12679)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173861.1"
                     /locus_tag="ME763_RS03525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03530"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_085568876.1"
                     /sec_met_domain="T2TS (E-value: 5e-13, bitscore: 47.1,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFLTITITPATADGTGGCTATKGALVAVDFGPFGGSVEEGCDLT
                     PTTGYDLLHDAGFSTAGTQHDGPAFICRIGYGSFNSGTQYPTSDKESCVLTPPATAYWS
                     YWIASPGQSDWTYSPYGAMDRKLKDGDVDAWVYGGTDVQGSTGKPTFTPDDVRGGGPSG
                     PGPGEPTGALGKIDTKAAATWLTGQLTDGERIVDDGATTPDYSLTADTAFALAAANGKS
                     ATLDKVTDYLAAHTADFAYPNGTGQAPDATAVARLALLAETTGRDPRAFGGRDLLAALT
                     AHVCAAGPESGEATPGCTAKGDFRASSYAEGQALAVLALLRAGVTPPAATVDRLTQLQC
                     KDGSFTSILIRPGEYCDPDPATTGLIALVLHRAGGHEDAVTAARTYLGGAQRADGAFPG
                     YTGSTTGSVNATAYAAQALAALGDTTRTAAAVGWLSRQQLDGGGFGFEEGATDPAVYAT
                     SPAVLAGTGTSLVTLTTKATEPTSPPTSPSGTPTAPAPGAGPDLKKGVAYLTKAANLKQ
                     GQYYGDGTGSGRADFGLTIDGAYALAATGLDNARLRGIVDFLDHRGKDGAGRTVDDWTN
                     VGTSYAAAGSIGKTALLAEAVGRDPRHFTGHDLIAALDQAVCAKASTGADRSCAAAGAY
                     TYAPSVFAQSLAVMAQLRAGDSTSAQRPIAYLESLQESSGAWPSLIPSTKDSDVDSTAI
                     AAMALDLAGGAKADRAVDKALSWLASRQLADGGFPGTAGDSVNSAALAVQGLSLDAPKY
                     AEQLAKARKFLASQQNGDGGFVVAKGSDDRRSDLRASTQAVGGATGISFGTLQRSLTGT
                     SPQPTPSPSGSAPDIVTTGDTAGTAGTGSTGGAGASGGGGILAATGVQAGALAAIAVLL
                     MLAGWRTVVVARRRTGTGGGR"
     regulatory      complement(12888..13018)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     regulatory      13082..13211
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            13316..14728
                     /locus_tag="ME763_RS03530"
                     /old_locus_tag="ME763_03535"
     CDS             13316..14728
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018100023.1"
                     /locus_tag="ME763_RS03530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03535"
                     /product="hypothetical protein"
                     /protein_id="WP_085567767.1"
                     /transl_table=11
                     /translation="MIRPLSLRRPALVAAAALGAFTLATLPAAATSSPAQITTSKTNGV
                     AYLKSLQAADGSYAGSGLSNEWAFSALASAGTAAVDVTPGGDTSKNARTVYRNLLSTAA
                     WPSASPVVTDYERAVLNAYAAGIDPARVSASRDLIADIYGYWQTSENGYFGPSANFNGT
                     VFAALALNGARTQSGQARIPAALRDSVVARIRANQHNDGGWNYGKAEGDSSQLAATSDI
                     DMTGAAMAALCTSGVPNTDSGIVRAKAFLKSKLVANSGAFNAMFGVNSDSNGWAVSGLN
                     ACGINAQTGDFLTPAGKTPVDFLIAQQFNPGGGFRYQPGDTSPTAYSSIDALRAVAGGG
                     FTAAPPAPTTPGAPQWVGQGSFTSGTATKLALSVDDGAGNLKVCSVALTPTGGTTTLGA
                     VLDAAKSAATPSGCVTDLTPATGSGTVTTLNGKANSGSSTWKVSIDGSTFATATRATAI
                     GVGDTIAVRWGA"
     gene            15713..16633
                     /locus_tag="ME763_RS03535"
                     /old_locus_tag="ME763_03540"
     CDS             15713..16633
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173859.1"
                     /locus_tag="ME763_RS03535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03540"
                     /product="cobalamin-binding protein"
                     /protein_id="WP_085567766.1"
                     /transl_table=11
                     /translation="MRIVSLLPAATDIVAALGLSAGLVGRTHECDWPPREVAEVPVVTG
                     AELDQAVLTSREISDAVGGSAHSGSSLYTLDTEALAALRPDVVLTQDLCAVCAVSYERV
                     SRAVRLLDGDTRVLSLEPRTLDDVLDCLVTVGELLDVRERALRLRAELRARLDRLRDSV
                     AGLDRPRVAAIEWLDPLWPAGHWVPEQITAAGGEPLLAVPGEHTEPVSWSAVRAARPDV
                     LLVLPCGFPPERTLREAELLTTLPGWPELPAVRSGRVWVLDGPSYYNRPGPRVVRGAEV
                     LAHVLHGVRAGKPVAPAEARPFPGR"
     gene            complement(16647..17135)
                     /locus_tag="ME763_RS03540"
                     /old_locus_tag="ME763_03545"
     CDS             complement(16647..17135)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018515170.1"
                     /locus_tag="ME763_RS03540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03545"
                     /product="DUF4430 domain-containing protein"
                     /protein_id="WP_085567765.1"
                     /transl_table=11
                     /translation="MHGTFARRTLITATALGLALAAAPATAHAQSAPGTNAPVRVTLTV
                     QGPDGILFKGKIRTRGHDVSTATGGTHTCDGTNGGANPSAVPTPTAALDDAAHRRHFTW
                     DGAWYASFDDYSVDTIKNVSGGASAYWNISVNGTPTPVGGCQFKLNAGDAVAFTWTAF"
     regulatory      complement(17297..17437)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(17414..17429)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.91"
                     /tool="antismash"
     gene            complement(17488..17841)
                     /locus_tag="ME763_RS03545"
                     /old_locus_tag="ME763_03550"
     CDS             complement(17488..17841)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192305.1"
                     /locus_tag="ME763_RS03545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03550"
                     /product="hypothetical protein"
                     /protein_id="WP_085567764.1"
                     /transl_table=11
                     /translation="MAGSVPCRVVVCRDCCCGSPKVTGVDHAAQTARLEAEVPLRISDC
                     LDVCDQANVIVVQPSATGRAAGGRPVWLGLVNDPEATEDIITWVRSGGPGVAPLPEILG
                     LYAFTPPGRTANP"
     misc_feature    17868..17883
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.08"
                     /tool="antismash"
     misc_feature    complement(17870..17883)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.89"
                     /tool="antismash"
     misc_feature    17870..17884
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.28"
                     /tool="antismash"
     gene            complement(17884..18717)
                     /locus_tag="ME763_RS03550"
                     /old_locus_tag="ME763_03555"
     CDS             complement(17884..18717)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003947391.1"
                     /locus_tag="ME763_RS03550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03555"
                     /product="sterol desaturase family protein"
                     /protein_id="WP_085567763.1"
                     /transl_table=11
                     /translation="MIPTVVYAIPAFVLLVVVEALSYRFLPDDDERGYELRDTVTSMSM
                     GAGSQVIAVPWKVATIVVYAAAYTAVPWHLSPSSGWTWLLLFFGDDLAYYAYHRAHHRV
                     RVLWASHVVHHSSLRYNLSTALRQTWTPMTGLPFWLPLALLGVPPWMILVEQAVSLVYQ
                     FFLHTERVDKLWRPVEWFFNTPSHHRVHHGSNQVYLDRNYGGILIIWDRLFRTFEPEGE
                     RVVYGLTKNIDSYNLVRVAFHEYAAAWRDVRAAVRWRDRAGYVFGPPGWSPRVGR"
     gene            complement(18714..19436)
                     /locus_tag="ME763_RS03555"
                     /old_locus_tag="ME763_03560"
     CDS             complement(18714..19436)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019349.4"
                     /locus_tag="ME763_RS03555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03560"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_085568875.1"
                     /transl_table=11
                     /translation="MTEGHIRREAVSDQLFALLRDRILGGALPAGSALTAERELAAEFG
                     VNRHAVREAVKRLQQARLVEVSHGGRTQVLDWRRTAGLELAVGIAAADSGPTVQDIARD
                     ALEMRACIGADAARLCALRCSARAAAEIAAAVEAHAQAGPDLTDLDETYIAWWRLIVEG
                     SGNIAYLLAFNSLVDGLIPVADVPADLGAGEILDVEAHRRLAGHITAREAGAAELLARE
                     LLTRSVPAAPRARKGARR"
     misc_feature    19428..19442
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     misc_feature    complement(19478..19492)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.69"
                     /tool="antismash"
     gene            19662..19871
                     /locus_tag="ME763_RS03560"
                     /old_locus_tag="ME763_03565"
     CDS             19662..19871
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670436.1"
                     /locus_tag="ME763_RS03560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03565"
                     /product="ferredoxin"
                     /protein_id="WP_046420515.1"
                     /transl_table=11
                     /translation="MQTVVDLTRCQGYAQCVFLAPDVFRLHGEEGLLYAPAVPDDQVER
                     VRQAAAACPVQAILLGEEVSGGAR"
     gene            19861..21216
                     /locus_tag="ME763_RS03565"
                     /old_locus_tag="ME763_03570"
     CDS             19861..21216
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670437.1"
                     /locus_tag="ME763_RS03565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03570"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_085567762.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.4e-44, bitscore:
                     151.3, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDDLTGGRIVVVGASLAGLRAAEALREQGFTGSLTVVGDEPHPP
                     YDRPPLSKQVLLGVAPADSTGLPMRRDPKAEWVLGVRATGLDTLGKRVLLDNGESLPYD
                     RVLIATGTRARPWPNPAEAALDGVFTVRTREDAAGLAAALDAGPRRVLVIGGGFTGSEI
                     ASACRERGLEVTVTERGPAPLVGALGGTLSKLAAAMQRNHGVDLRTGVTVTRLLGEKTF
                     TGVELSDGNQVDADVCVVALGAVRNVEWLADSGLAAGPRGLACDAGCRAFTMYGIVTDD
                     VFVAGDVSRFPHPLFGYQLLSLEHWGNAVTQAEVAAHNMVNPGPLRRPHLALPTFWSTQ
                     FGLNIKSVGVPTYSDHVVIAQGSLEARRLAMVYGYRGRVTAAVTVDMAKSLDYYQHLIE
                     TGAPFPPPPGAADRALAAEIPIPSDVPDPSVLSHGPTVALTGYLPDRRLTVV"
     gene            21242..22423
                     /locus_tag="ME763_RS03570"
                     /old_locus_tag="ME763_03575"
     CDS             21242..22423
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018560902.1"
                     /locus_tag="ME763_RS03570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_03575"
                     /product="cytochrome P450"
                     /protein_id="WP_085567761.1"
                     /sec_met_domain="p450 (E-value: 3e-29, bitscore: 100.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDPGTLLARITDYASRPDPYPLYAELREAGTVVPQADGSLLIGGY
                     HEVAALLHDPRMSADPRTRGLETAKPPFLRLDDPEHHRLRTLAMRPFGPPHTPHRVDGM
                     RTEIENITKELLAPFESGGQVDVVDDFAYPLPVTVICRLLGVPHEDEPLFRAWSDTLVA
                     SADVRPDASSAPRDEAERARQEMGGYLVGLAEQRRDDPRDDLLSAFVSEPDPELRLSQE
                     ELAQTAVLLLIAGHETTVNLITNGVLTLLRHPEELDRLRREPELMPRAVEELLRFEPPV
                     HMRERIPLADFDVAGTTLPRGSSVFLALAAGNRDPRRFTDPDRFDPARADNEHLGFGSG
                     IHLCYGAPLARLEAQSALTALLPRLGTAELVEDPPPYRQNAMLRGPRHLTLRF"
     misc_feature    22641..22656
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.64"
                     /tool="antismash"
ORIGIN
        1 ggccagctcg cagccgccgc cgagggcgta cccggagacc gcggcgacgg tcggggtgcg
       61 cagctgtccg agccggtccc aggcggtgaa ccagtcggcg aggtacatgt ccatgtaccc
      121 ccgcgggctc atctccttga tgtcggcgcc cgcggcgaac gccttcgcgg agccggtgat
      181 cacgacgcag ccgcactccg gatcccggtc cagggcctcg gacgcggcca cgacctcgtt
      241 catgacctgg aggttcagcg cgttgagggc cttggggcgg tcgagggtga gcagggcggt
      301 acggcccttg cgctcgaccc ggatcgtctc gtactcggtg ctcatgcgcg ctctccgctc
      361 tgttccctga tggtgcgtac gatgcccgag aagtcctcgg cggcgccgac gcgttcggca
      421 tattcggcgt acaactcggc tgccctgagc ccgagttcgg cctgtacacc gcccgccttg
      481 accgcgttgg cggcgaggcc cagatccttg gccatgagcg cggcggcgaa gccgggccgg
      541 tagtcccggt tggcggggct cgtcgggacc gggcccggga ccgggcagtt gacgctgagc
      601 gcccagcact gtccggacgc cgtggacgcg acgtcgaaca gggcctggtg ggacagtccc
      661 agtcgctcgc cgaggacgaa cgcctcgctc acggcgatca tggagacgcc gaggatcatg
      721 ttgttgcaga tcttcgccgc ctgcccggca ccggggccgc cgcagtgcac ggccttgccg
      781 cccatgacgt ccaacagggg gcgggcgccc gcgaattcgg cctccccgcc gccggccatg
      841 aaggtcagcg tgccggcctc ggcgccgacc actccgccgg agacgggtgc gtccagcgcc
      901 cgcatcccgg cggcgacggc gcgttcatgg gcggtgcggg cgtcggcgac gtcgatggtg
      961 gagcagtcga cgaagagggt gccgggccgg gcggccggga gcagggtgtc gtagaggtcc
     1021 aggacatggc ggcccgcggg gagcatggtg agcaccgtgt ccgcgtcggc caccgcctcg
     1081 gccgcggatc cggcgggctc cacccccgcc cgcacggcgg ccgccagcgc ctcgggcacc
     1141 aggtcgtgtc cgcgtacccg gtgcccggcc tcgaccaggt tggcggccat cggaccaccc
     1201 atgtgcccga gcccgatgaa ggcgacggtg cggcgcgccc cgccgtcccc gctcaccgcg
     1261 ccgcctccgt cgtgccgccg ggtcccgcga gcccgagttc gcggtcgccg agcggggcga
     1321 agaagcgctc cacgtcggcg tcgccgacct cggccagggt cgccggtgac cagtgcgggt
     1381 cccggtcctt gtcgatgatc tgggcgcgga cgccctccac caggtcgggg ctccgcagcc
     1441 cgacgcacga gacgcggtac tcctggtcga ggacctcctc cagggtcccg agccggcggg
     1501 cgcggcggag ggcggcgagg gtgaccttga gcgcggtggg cgacttggcg agcagggtct
     1561 cggccgcctc cttggcctcc gtgccgccgt gcgcgaacag ccgctcgacg atctcctcga
     1621 cggagtcggc ggagcagcag gcgtcgatcc agctccgctg ctcggtcaac acccccttcg
     1681 gtgcgggctg ttcgtgccgt gccagggcct cggccacggg cagcgcggcg aggtcggcca
     1741 gcagggcgtc cagggcgtcg gagggcacgt agtggtcggc gagcccgcac agcagggcgt
     1801 caccggcgcc gatctggttt cccgtcaggg cgagatgcgt acccagctca ccgggtgcgc
     1861 gggagagaag gtaggtgccg ccgacgtccg ggatgaagcc gatcccggtc tccggcatcg
     1921 cgatccgcga gcgctcggtg acgacgcgga ccccgccgtg cgcggagacg ccgaccccgc
     1981 cgcccatcac gatgccgtcc atgagggcga catagggctt ggggtagcgg gcggtgcggg
     2041 cgttgaggtg gtactcgtcc cgccagaacg cggccgaggc ggtgccgtcg cccgcccggg
     2101 cgtcgtcgtg gatggcgcgg atgtcgccgc ccgcgcacag tccgcgcgct ccagcgccgc
     2161 tgatgacgac ggtccgcacg gccggatcgt gctcccagtc ggtcagcgcc gcgtcgatgc
     2221 gggtgaccat ctcatgggtg agggcgttga gggccctggg ccggttgagg atgatccggg
     2281 cggcccggcc ttcggtacgc aggaggacgg gttcctcggt gtcgttgctc atccgagggc
     2341 ctccgtcagg ccgcgggcca cgatgacgcg catgatctcg ttggttcctt ccaggatctg
     2401 gtggacgcga aggtcgcgga cgatcttctc aatgccgtac tcggcgaggt agccgtatcc
     2461 gccgtgcagt tgcagggcgc ggtcggcgac cgagtacccg gtgtcggtgg cgaaccgctt
     2521 cgccatggcg cacagatacg gtgcctgcgg gtccccggcg tccagggcgc gggccgcctg
     2581 ctggaccagg gcgcgggcgg cggtcagctc ggtcgccatg tcggcgaggc ggaagcgcag
     2641 ggcctgggcg tcgaggaggc gggcgccgaa cgcctcccgg tcggcgaggt gggcgaggct
     2701 gcggtccagg gcgctgcggg cgccgccgag ggagcaggcg gcgatgccga gacggccgcc
     2761 gttcaggccg ttcatcgcga tccggaaacc ctcgcccgca cggccgagga gccggtcggc
     2821 ggggatccgg acgccgtcca ggacgacctg gcgggtgggc tgggcgtgcc agcccatctt
     2881 gcgttcgttc gggccgaagg agatgccggg gtcgtccttg tcgaccagga aggcggagat
     2941 gccgcggggg ccgggttcgc cggtgcgggc catcaccacg tacacctggg cggcgcccgc
     3001 gccggagatg aactgcttga cgccggtgag cacgtagtgg tcgccgtcgg gtacggcacg
     3061 ggtggtgagg gcggccgcgt cggagccggc gccgggttcg gtcaggcagt agctcgcgag
     3121 gtcgtccatc gcgcacagcc ggggcagccg gcgctcgcgc tgggcgtcgt cgccgtagtg
     3181 gtcgatcatc caggcgacca tgttgtggat ggacagatag ccggcgatgg cggggcagcc
     3241 ggaggccagg gcctcgaaga cgagcacgcc gtcggcccgg ccgagggcgg atccgccgtg
     3301 ctgttcgcgg acgtagacgc cgccgaggcc gagccccgcg gccttgcgca ggacgtcgac
     3361 ggggaagtgc cggtcgcggt cccagtccag ggcgtgcggg gcgaggtggt cctgggcgaa
     3421 gtcgagggtg gtctcgacga gggctcgctg gtcctcggtg agcagggtgg tggtcatacg
     3481 gcgctcagcc catcgtgggg atcgtgaagg aggcgccctc gcggcggccg gcgggccagc
     3541 gggaggtgac ggtcttggtg cgggtgcaga agcggatcgc gtccgggccg tgctggccga
     3601 ggtcgccgaa gccggagcgc ttccagccgc cgaaggtgtg gtgggcgacg ggcaccggga
     3661 tgggcacgtt cacgccgacc atcccggtgt tcacccggcg ggtgaagtcg cgggcggtgt
     3721 ccccgtcgcg ggtgaagatc gcgacgccgt tgccgtagcg gtgctcgctg ggcaggcgca
     3781 gggcctcctc gtagtcggcg gcgcgcacga ccgagaggac cgggccgaag atctcctcct
     3841 ggtagatccg catgtccggg gtgacccggt cgaagaggga ggctccggcg aagaagccct
     3901 tctcatggcc ggggagcacg aagtcccgtc cgtccacgat gagttcggcg ccctcctgga
     3961 ccccgaggtc gacgtactcg cggaccctgc gcagggcctc gggggcgacc agcgggccga
     4021 agtcggcctc ggggtcgtcg ctgcggccga tccgcagggc ggcgatgcgt tcggtgagcc
     4081 gggcgacgag ggcgtccgcg gtggccgcgc cgaccggcac ggcgaccgag atggccatgc
     4141 agcgctcacc ggccgagccg tatccggcgc cgatcagcgc gtccaccgtc tggtccagat
     4201 cggcgtccgg catcacgatg aggtggttct tggcgccgcc gaagcactgg gcgcgcttgc
     4261 cgtgggctgc ggcggtggcg tagacgtgcg cggcgatcgg ggtggagccg acgaagccga
     4321 gggcggcgac gcgcgggtcc tccaggaggg tgtcgacggc gtcccgggcg ccgttgacga
     4381 cattgagcac gcccggcggc aggcccgcct caaggaagag ttcggcgagc cgcagcggca
     4441 ccgacgggtt gcgctcggag ggcttgagga caaaggcgtt gccgcaggcc agggcgggtg
     4501 cggcctgcca gagcgggatc atggcgggga agttgaacgg ggtgatgccc gcgatgacgc
     4561 cgaggggtgc gcgcagggag tgcacatcga tgccggtgcc ggcgttgtcg ctgaactcgc
     4621 ccttgagcag gtgcgggatg cccgcggcga actccacgac gtccaggccg cgctggaggt
     4681 cgccgtgggc gtcggcgacg gtcttgccgt gctcggccga cagcagccgg gccagcgcgt
     4741 ccttctcctg ctcggcgagc tggaggaagc gcagcaggac gcgggcgcgg cgctgcgggt
     4801 tccactcggc ccaggcgcgc tgtgcctcgg cggcggaggt gatcgccgcc gtggtctcgc
     4861 cccggtcggc gagcggcacc agggcctgga cctcgccggt gttggggtcg tacacctcgc
     4921 cgtgggcccc ggaggtgccc aggaagtgct caccgtcgac gaagtgggtc aactcgcgta
     4981 cggcggaggg tgcttgggga cggatcatgg ctgcctgctc tcgtcaggtg ggggtgatcc
     5041 gggatggcgc gcggcagcgg cacacggccg gatgcgcgag ggcgcgtgcg ggcgtaccgg
     5101 ggcggcgcga aagacgcggt ggcgggacga gccctcagac cggtacggcg ggattgccgc
     5161 gcggggacgg cccgcgtcgg ttcgcgccgg gatcatgggt gcgcaggggt gccatgcgtg
     5221 tcggctccat cctcgtggac aacacggaac atcccgcggc cggtatcctg actcccggat
     5281 cagcgcgcgc cgtccgcctt cccgacatcc agctcgtcag tggcgtcctg ctcgacggcg
     5341 tactccccgg tcacagtggc gggaccgcgc cggattcgca ccggcttccc tgcaccgcgg
     5401 gccttctccc ccgaatatat agttggacgt cctagtaaat ccagtgtccc cggggattcg
     5461 gtgcgtcttc acgccacgcc gtccgcgccc cgcgcgggcc gcttccgggg ctctgcgaag
     5521 cgcaccggtg cccggaagcg ggcgcggcgg gcggcgcgcc ggaaggtggt cagcaccgcg
     5581 ggaccggcca gcagcacgca cacgaagttg gtgacggccc ggccggtgtc ccagcccagc
     5641 gaggtggcga ggtcgaaggc gacgtagcgg tgccactgct cggtgaaggg caggcccggc
     5701 agataggcga tcgagctgtt cgggtccagg gagaacggcc agaaggagag gttgagcagg
     5761 aagccgaaga ggtagccgga cagcgagccg tagacggcga gcatcagcac ctcgcggcgg
     5821 ccgctcgccc ggggcaggaa tccggcgagc atgccgacga acgcgcagcc gaacatctgg
     5881 tacggcatcc agggccccac tcccccggtg atcagcgccg aggcgaacag cgaggtgcag
     5941 ccgaggacga agccgaagcc cgggccgtac acccggccgg ccaggaccaa gacgaagaag
     6001 accgtctcga tgcccgccgt accggccccg agggggcgca gggcggcgtc gacggcggag
     6061 agcacgccga gcatggcgag cgccttggag tcgatgccgc cctcggcgat ctccgagagc
     6121 accacgcaca gcaccagcac cagcagcacg ccgaagatca gtgggggcgc gtaggaggag
     6181 ccgaacgtgc cgggtgcgac cacgaacggc cagaagaacg cgacgagtcc gaggagggcg
     6241 gcgagcgcca tgaccactgc ggcccggccg gtcagccgga tggcgggtcc cccggccccc
     6301 gcgcgtccgc tcatgagcgc gcctcgtccg tgtccgcgag cgcgcgtgcg acctgatcca
     6361 ccgtcaggaa gggcagtggc gcgaggatct tggccgtctg cggggcgaac gtcggggagg
     6421 agacgatgac ttcggtggtg gggccgtcgg cgacgatgtc cccctcggcc atgacgacga
     6481 cccggtcggc ggcgcgggcg gcgaactcga cgtcatgggt ggagatgacg accgcacggc
     6541 cctcggccgc cagcgcgtcc acgatggcgg tcagtgccgt cttggcccgg tagtccaggc
     6601 cccgggtcgg ctcgtccagc agcacgaccc ggggcgcggc ggccagttgg acggcgagga
     6661 cgagggcgag cttctgcccc tccgacagat cgcgggggtg cgtggcgtcc tcgatgccgg
     6721 gcgcgagccg gtcgagcagt tcgcgcgccg tcaccccggc cgccgactcg gcgtccgcct
     6781 gggcgagttc ctgtccgacg ctctccaggt agagcaggtc ggcgggcgtc tgcgggacca
     6841 gtccgacgag tcggcgggcc tcggcggcgg acaccgtgtg cgggtccttc acgccgtgtt
     6901 cgccgtgcac ccggacgctt ccggcccggc ggggtccaga accctggagg gcccacagca
     6961 gggaggactt gccggagccg ttgcggccca tcagcgcgac gacctcgccc gcgtgcagat
     7021 cgaggtccac ggcgcgtacg gcggcgaggt cccggtaggc gaccgtgacc ccgcgtgcgg
     7081 ccagcagccg gttcccgccg ccgcctggaa ccggcggccg tacgggggcc ggggtccgct
     7141 cggccagccg ggcgcgcagc ggggcggcgg cgcggcgggc gtcgcggatg gacagcggca
     7201 gcggggacca gcccgcggcc cggcccagct ccacgatcgg gggcgcgatg gtggccgtac
     7261 gcaggatctc ggcgggcggc ccgatgcggg cgcggccgtc gccgggcagg tggatgacgc
     7321 ggtccgcgta ctgcacgacc cgctccaggc ggtgctcggc catgaggacg gtgacaccga
     7381 ggtcgtggac cagccgggtg acggcggcga ggacctcctc ggccgccgtc gggtccaggg
     7441 ccgaggtggg ttcgtccagg accaggacgc gtgggtgggc ggtgagcacg gagccgatgg
     7501 cgacgcgctg ttgctgtccg ccggagagcg tgtgcagcgc gcggtgccgc agatcggcga
     7561 ggccgagcag atcgagggtc tcctcgaccc gcttgcgcat ggtcgcgggc gggatcgcca
     7621 actgctccat ggcgtaggcg agttcctcct cgacggtgtc ggtcacgaag ccgtcgatgg
     7681 ggtcctggcc caccacgccg acgacatcgg cgagttcgcg gggcggatgg tgggcggtgt
     7741 cgcgcccgtc gacggtgacc cggccgtaca gggtgccgcc ggtgaagtgc gggaccagcc
     7801 cgttgacggc gccgagcagg gtcgacttgc cgacgcccgt gtggccggtg acgaggcaga
     7861 gttcgccctc gtccaccgtg agggcgacgt cccgcagggc gggctcgggc atgtcgtcgt
     7921 agtggacggt gacctggtcg aaggtgatca cggtgcggtg gctctcggga cggggccggg
     7981 cggcggggcg agaaagccgg cggtgccggc gagcaggacg gcggcggtcg gcaccagcgg
     8041 caggccgggc caagtgaggg ggtagtaggt ggggttgagc tgggcggggt cgtagccgag
     8101 atcgctgaag agcagcacgg cggagagcac tccgctgccc gcgacgcacc actccggcag
     8161 gcgccagggg tcgggccggt aggcggtgcg ggtgacacgc cggccgccga gccgcaggcc
     8221 cgccacgcac agggcggctc cgcaggtcat cgcgggcagc ccgaggaggg tgggcgcggt
     8281 ggcgtcgagg agtccgtacg ccccggcaca cagaccgcac atgcccagca gcatcagcgc
     8341 gccggtgatc cggcgggagc ggcgggtggc gctgcccgcc cggccgtagc cgcgtgagtc
     8401 catggcggcg gccagccgca gggagcgttc cagggcgtcc tcaaggaccg ggaccgcgat
     8461 ggcgcgcagc gccttgacgc ccttggcccg gccggcccgc aaccgccgtg cgcgggcgac
     8521 gcgttggacg ctctgcacca gctggggcgc cacgctgatc gcgacggtga cggccacgcc
     8581 cagctcgtac agggcgcccg gcaggacgcg cagggcgcgc ttggggttgg cgagggtgtt
     8641 ggcggcgccg acgcaggcca gcatgcaggc gaggcggagc ccgtcggtgg cggaggacag
     8701 cagggcctcc agggagaccg ggccgccgat ctggatgccc gcgtaccagt cgggggtggg
     8761 gaggtgcggc agggagaaga ggaagtggtc gtgcggcgtg atgccggtgg cgaacacggc
     8821 ccggaagacg acgcggatcg cgaccaccga cagggcgagg tacaggtagt agacgaagcc
     8881 gcgggcccag ggcgcctcgg tgcgccgggc ggtgacgacg tagccgagga cggcgagcac
     8941 caggagcagc agcagcgggt tgtcggtacg gctgaccgcg gtggcgagcg cgagcgccca
     9001 cacccaccag gccatggggt gcagggtgcg gggcagccgg cggccgcccc ggtccggtgc
     9061 cgccgcggcg gcgggtgcct cgacggccgt acgggacacg gcggtcactc ggagcggcgg
     9121 cgccggtgtg ccgcgtaggc cgcgccgccg atcaggacga ccagaccggc gcccgcggcc
     9181 acagggacga tcgagccggc gtcgtgccgg gcctcggcgg cgggggcggc gtcgaccacc
     9241 cgggtgccgg tgctcgggga cgggggcggg ggcggggccg ccggggcgct cgtggtggtg
     9301 ctcggcgacg gcgacgggct cgcactcctg ctgggcttgg gcttcgtcga cggcaaggcg
     9361 gagggggcgg gctgcttctc cggggccggt cctgtgttca cgccgggcgg cagctcgggg
     9421 gccttgcggg tggaggcggg cttgcccgcg tcgccctgcg gcgcggtgtt gtgggcgcgc
     9481 agctggtcgg gggtgacctt cgggcggccc tcggtgccct ggatgttcgt gccgccgaac
     9541 tcccacaggt cgacgctgcc cggctcgggc ttgtagagca tcgcgccgag ctggctgtac
     9601 gtccagtcgg tggcgccggg atcggcgtgc cagtacgacc agtacgcgga ggcgggcggg
     9661 gtgagcacgc agtcgtcctg ggcgggggtc ggatactgcc ggccgtgctg gtaaccgctg
     9721 tagccgatgc ggcagatgaa ggcggggccg tcgtgcccgg tgccggtggt gctccagccg
     9781 ccctggttga gcagctcgta cccggtggtc ggggtggtgc cgcaggagcg caggatcggg
     9841 ccgccccagt ggctgaggtc gacggcgagc acgacacccg agctggtggt gcagcggccc
     9901 atcggctgcg ggtcggcggc ggccggggtg ccggtctgga cgacggcggc cgcgccgagg
     9961 ccgagggcgg ccagggcccg gatcgggcgg gccaccgccc tcatcgtccg cccccggtgc
    10021 cggtgcggcg gcgggcgacg accaccgtgc gccagccggc gagcatcagc agcacggcga
    10081 tcgcggcgag cgccccggcc tggacgccgg tggcggcgag gatgccgcca ccgccgctcg
    10141 cgccggcccc accggtgctt ccggtgcctg cggtgcctgc ggtgtctccg gtggtgacga
    10201 tgtccggggc gctgccgctg gggctcgggg tgggctgcgg ggaggtgccg gtcaggctgc
    10261 gctggagggt gccgaaggag ataccggtgg cgccgccgac ggcctgggtg gaggcgcgca
    10321 ggtcggagcg gcggtcgtcg ctgcccttgg ccaccacgaa tccgccgtcg ccgttctgct
    10381 gggaggcgag gaacttacgg gccttggcga gctgctcggc gtacttcggc gcgtccagcg
    10441 acagcccctg tacggcgaga gccgccgagt tgacggagtc gcccgcggtg ccggggaagc
    10501 cgccgtcggc cagctgccgg gaggcgagcc agctcagcgc cttgtccacg gccctgtccg
    10561 ccttggcgcc gcccgcgagg tcgagggcca tggcggcgat ggcggtggag tccacgtcgg
    10621 agtccttggt ggacgggatc aggctgggcc aggcaccgct gctctcctgg aggctctcca
    10681 ggtaggcgat cggccgctgg gccgacgtgc tgtcgcccgc gcgcaactgg gccatgacgg
    10741 cgagggactg ggcgaagacg gagggcgcgt aggtgtaggc gcccgcggcc gcgcaggagc
    10801 ggtcggcgcc ggtgctggcc ttggcgcaga cggcctggtc gagggcggcg atgaggtcgt
    10861 gtccggtgaa gtgccggggg tcgcgtccga cggcctcggc gagcagggcg gtcttgccga
    10921 tggagccggc cgccgcgtac gaggtgccga cgttcgtcca gtcgtccacc gtgcggcccg
    10981 cgccgtcctt gccccggtgg tcgaggaagt cgacgatgcc gcgcagcctg gcattgtcca
    11041 ggccggtagc ggcgagcgcg taggcgccgt cgatggtgag gccgaagtcg gcgcggccgg
    11101 agccggtgcc gtcgccgtag tactggccct gcttgaggtt ggccgccttg gtgaggtagg
    11161 cgacgccctt cttcagatcg gggcccgcgc ccggggcggg ggcggtcggg gtgccgctcg
    11221 gcgaggtcgg cggcgaggtg ggctcggtgg ccttggtggt gagggtgacg aggctggtgc
    11281 cggtgccggc gaggacggcg ggcgaggtcg cgtagacggc cgggtcggtg gcaccttcct
    11341 cgaagccgaa gccgccgccg tcgagctgct gccgggacag ccagccgacg gccgcggccg
    11401 tgcgggtggt gtcgccgagg gcggccagtg cctgggcggc gtacgcggtg gcgttgacgg
    11461 atccggtggt cgagccggtg tagccgggga aggcgccgtc cgcgcgctgg gcgccaccga
    11521 ggtaggtgcg ggccgcggtc accgcgtcct cgtggccgcc cgcccggtgc agcaccaggg
    11581 cgatcagccc ggtggtcgct ggatccgggt cgcagtactc gccgggccgg atcaggatgc
    11641 tggtgaaact gccgtccttg cactggagtt gggtgaggcg gtcgaccgtc gcggccgggg
    11701 gtgtcacccc ggcccgcagc agggcgagga ccgcgagggc ctggccctcg gcgtaggagg
    11761 aggcgcggaa gtcgcccttg gcggtgcagc cgggggtggc ctcgccggac tccgggcccg
    11821 ccgcgcacac atgggcggtg agggcggcga gcaggtcgcg gccgccgaag gcgcgcgggt
    11881 cgcggccggt agtctcggcg aggagggcga gccgggcgac ggcggtggcg tcgggggcct
    11941 ggccggtgcc gttcgggtag gcgaagtccg cggtgtgggc ggcgagatag tcggtgacct
    12001 tgtcgagcgt ggcgctcttg ccgttcgcgg cggccagcgc gaacgcggtg tcggcggtca
    12061 gcgagtagtc cggggtggtg gcgccgtcgt ccacgatcct ttcgccgtcg gtgagttggc
    12121 cggtgagcca ggtggcggcg gccttcgtgt cgatcttgcc cagggcgccg gtgggctcgc
    12181 cggggccggg cccggagggg ccgccgccgc gtacgtcgtc gggggtgaag gtgggcttgc
    12241 cggtggagcc ctggacatcg gtgccgccgt agacccaggc gtcgacgtcg ccgtccttga
    12301 gcttgcggtc catggcgccg tacgggctgt aggtccagtc gctctggccc ggggaggcga
    12361 tccagtacga ccagtacgcc gtggcgggcg gggtcaggac gcaggactcc ttgtccgacg
    12421 tcgggtactg cgtaccggag ttgaaggagc cgtagccgat gcggcagatg aaggcggggc
    12481 cgtcgtgctg ggtgccggcg gtgctgaagc cggcgtcgtg cagcaggtcg tagccggtgg
    12541 tgggggtgag gtcgcagccc tcttccaccg agccgccgaa gggcccgaag tccacggcga
    12601 cgagtgcgcc cttggtcgcg gtgcagccgc cggtgccgtc cgccgtcgcg ggtgtgatcg
    12661 tgatcgtgag gaaggtcatg caggccgcga gcagggtgca cagggccgcc gccagggccg
    12721 ccacgcgggg cgggatcgcc ctcgcccgct cgtctcttcg ctgcccggtc cccaccacgg
    12781 ccccctcggt cggccggcgg gggcacgggc gtggcagagg ggccccgggg gcacggaagg
    12841 agcccggaag ccggtcgcac cacgccgcag tccacgacgg cgtctgttgc agatgtcacg
    12901 ctccaggcag tccggctcgc ccgggacggt gccgggccta cggttgcggg tcagcgccgg
    12961 aattcgaccg gcttcccctg gaactcattg cgtatcagcc ggatttgagc acgcttcacc
    13021 gaatgcgtca agagcggtgg gagacgtggt tgtcgggtga agaacgggcg ctggcgggcg
    13081 ggttggccgt cgggtaccgt ctcggtctgc cgaatggggg aacccggtgg gagtccgggg
    13141 ctgacgcgca gcggtatggg acggcggggc cgttccgagc ccgaatgccc aggcggcgca
    13201 gcacttttgg aagccggtcc acgcgttccg gacggcggcc agcgctcgct gctccgccgg
    13261 ttcgacgggc cgtggcaccg ggccgggtcg gcgtcctcca tccaaggagc aggccatgat
    13321 ccgtccgctg tccctccgcc gccccgcgct cgtggcggcc gccgcgctcg gcgcgttcac
    13381 cctcgccacg ctgcccgccg cggccacgtc ctccccggcg cagatcacca cgtcgaagac
    13441 gaacggcgtc gcctatctca agtcccttca ggctgcggac ggttcgtacg ccgggtcggg
    13501 gctgtccaac gagtgggcgt tcagcgcgct cgcctcggcc gggaccgccg cggtggatgt
    13561 gacacccggg ggcgacacga gcaagaacgc gagaaccgtc taccggaatc tgctctcgac
    13621 cgccgcctgg ccgtccgcgt cccccgtcgt cacggactac gagcgtgccg tgctgaacgc
    13681 ctacgccgcg ggcatcgatc cggcccgggt gtccgcctcg cgggatctga tcgccgacat
    13741 ctacggctac tggcagacct cggagaacgg ctacttcggc ccgtcggcca acttcaacgg
    13801 caccgtgttc gccgcgctcg ccctgaacgg cgcgcggacg cagtccgggc aggcgcggat
    13861 accggcggcg ctgcgtgact ccgtcgtcgc ccggatccgg gccaaccagc acaacgacgg
    13921 cggctggaac tacggcaagg cggaggggga ttcgagccag ctcgccgcca ccagcgacat
    13981 cgacatgacc ggtgccgcga tggccgcgct gtgcacgtcc ggcgtgccga acaccgacag
    14041 cgggatcgtc cgggccaagg cgttcctgaa gagcaagctg gtggccaaca gcggcgcttt
    14101 caacgcgatg ttcggcgtga actccgactc caacggctgg gcggtgtccg ggctcaacgc
    14161 gtgcggcatc aatgcgcaga ccggtgactt cctcaccccg gccgggaaga ccccggtgga
    14221 cttcctgatc gcgcagcagt tcaaccccgg cggcggcttc cggtaccagc cgggtgacac
    14281 ctcgccgacc gcgtactcgt cgatcgacgc cctgcgcgcg gtggccggcg gcggcttcac
    14341 cgcggcgccg cccgcgccca cgacgccggg cgcgccgcag tgggtgggcc agggttcgtt
    14401 cacctccggt acggcgacga agctggcgct gagcgtggac gacggggcgg gcaacctgaa
    14461 ggtgtgctcc gtggcgctca cgccgaccgg cggcacgacc acgctgggcg ccgtcctcga
    14521 cgccgccaag agcgcggcca ctccgtccgg ctgtgtcacg gacctcaccc cggccaccgg
    14581 ctccggcacc gtcaccaccc tcaacggcaa ggcgaacagc ggctccagca cctggaaggt
    14641 cagcatcgac ggctcgacct tcgccaccgc cacccgcgcc acggccatcg gcgtgggcga
    14701 cacgatcgcg gtgcggtggg gggcgtgacg ggggcgtgac ggggggcggc gcctgagggg
    14761 cggtgctcta cgaggcgggc gctcgaaggg ggcgcccgcc gcagggcgtt cggcatgacg
    14821 cgctcacccc ggggagcact cagcggccga tgccggaggc gccagatcgt tcggcgcatc
    14881 gcgccggatc cgacaccggg acgcgaagtc gacgcggacc accggctacc cggcaaccac
    14941 tcggcacagg gcgcccaaca ccgggctctc gccacggagg cgcccaccag ccgatgccgg
    15001 aggcgccaga tcatccggcg catcgcgcac cggatccgac accgggacgc gaagtcgacg
    15061 cggaccaccg gctacccggc aaccactcgg cacagggcgc ccaacaccgg gctctcgcca
    15121 cggaggcgcc caccagccga tgccggaggc gccagatcat ccggcgcatc gcgcatcgga
    15181 tccgacaccg ggcgcccggg gcacgacgca cggagtcagc gcgggtcacc ggctatccgg
    15241 cactcgcccc cgccgcgcct tcctgaagga aattcgggac gcggcacccg ccgcacggca
    15301 cagggcagcg gccgctcggc gcatcagagt gcggagcggc gcggtcgccg gccggcgcat
    15361 cgggacggca cgcgcctcct accactcgcc ccgaggccca atgaacgcgg cacgcggcgg
    15421 acgaggatcg gcgtgaagca gctcgccccg ttcgccgcgc ccggtgaacg gcacggcgat
    15481 gcctccgctc ggcgtacgag gtgcgccgta aagcgtgctc acccggcacc ggaggtacag
    15541 cgcgcggcgg gccccgcccc aggcgccggc ccgctgtgcc ccgctcggcc ccactccagg
    15601 cggccccgtc ggcgctggac gtaccccctg gtcggccccc gccccgagcc acccgggccg
    15661 ccgccctcct ctcggcccca ccccaagcgc gcccccggca taggctcagc gcatgcggat
    15721 cgtctccctt cttcccgccg cgaccgatat cgtcgccgcg ctcggtctct ccgcgggcct
    15781 ggtcgggcgt acgcacgagt gcgactggcc gccccgggag gtggcggagg tgccggtggt
    15841 gaccggggcg gagctggatc aggccgtgct gaccagccgg gagatctccg atgccgtcgg
    15901 cgggtcggcg cactcggggt cgtcgttgta cacgctcgac accgaggcgc tggcggcgct
    15961 gcgacccgat gtggtgctca cccaggacct gtgcgccgtg tgcgcggtgt cgtacgagcg
    16021 ggtgagccgg gccgtacggc tgctcgacgg ggacacccgg gtgctcagcc tggagccacg
    16081 caccctggac gacgtactgg actgcctggt caccgtcggc gaactgctgg acgtgcgcga
    16141 gcgcgcgctg cgccttcggg ccgaactgcg ggcccggctg gaccggttga gggactcggt
    16201 cgccggactc gaccggcccc gggtggcggc gatcgaatgg ctcgacccgc tgtggccggc
    16261 cgggcactgg gtgccggagc agatcaccgc cgccgggggc gaacccctcc tcgccgtgcc
    16321 cggcgagcac accgagccgg tgtcctggtc ggcggtgcgc gccgcgcggc cggacgtgct
    16381 gctcgtcctg ccgtgcggct tcccgcccga acgcaccctg cgggaggccg agttgctcac
    16441 gacgctgccg ggctggccgg agctgcccgc cgtacggtcc gggcgggtct gggtgctgga
    16501 cgggccgtcg tactacaacc ggccgggacc gcgagtggtg cgtggggcgg aggtgctggc
    16561 ccatgtcctg cacggggtgc gggccgggaa gccggtcgca ccggccgagg cgcgtccgtt
    16621 ccccggccgg tgaggagcgg gccggatcag aacgcggtcc aggtgaacgc cacggcgtcc
    16681 ccggcgttca gcttgaactg gcagccgccc accggggtgg gcgtgccgtt gacggagatg
    16741 ttccagtagg cggaggcgcc gccgctgacg ttcttgatgg tgtcgacgga gtagtcgtcg
    16801 aacgacgcgt accaggcgcc gtcccaggtg aagtgccgcc ggtgggcggc gtcgtcgagg
    16861 gccgcggtgg gcgtcggcac ggcggagggg ttggcgccgc cgttggtgcc gtcgcaggtg
    16921 tgggtgccgc cggtcgcggt gctgacgtcg tgaccgcggg ttctgatctt ccccttgaag
    16981 aggatcccgt ccggcccctg gacggtgagc gtcactcgga ccggggcgtt cgtgcccggt
    17041 gcgctctggg cgtgggcggt cgccggcgcg gcggcgaggg ccaggccgag ggcggtcgcg
    17101 gtgatcaggg tgcggcgtgc gaaggtgccg tgcaagagct gagccttcct gggcgggcgg
    17161 cccgcggcct cgtcgccggg cgcgcgaggc gcacccgggc ggctccgggc acctccgctc
    17221 gcgcggaccg gtggacgggc cgggcccggt gctccgggca tggctctcgg cttcgcgctg
    17281 cggaccatga cagtgggaag cggttccagc acgtgccggg cagcccgact cgcggcccac
    17341 ggccgcacac ggttgcaggt cagcgccgga ttcccaccgg cttcccccag tcacgcactt
    17401 atgcggttgt tgtgcgaacg gtgttcattc taggggaagt tggtgaagac gggccagaac
    17461 tccggctgat tctccggccc ttgggcctca ggggttcgcc gtgcgccccg gtggggtgaa
    17521 ggcgtacagc ccgaggatct ccggcagcgg cgccacgccc ggaccgccgg accgtaccca
    17581 ggtgatgatg tcctcggtcg cctccgggtc gttgacgagc cccagccaga ccgggcggcc
    17641 accggcggcg cggccggtgg cggagggctg tacgacgatg acgttggcct ggtcgcacac
    17701 atcgaggcag tcggagatcc gcaggggtac ctccgcctcc agccgggcgg tctgtgccgc
    17761 gtggtcgacg ccggtcacct tcgggctgcc gcagcagcag tcacggcaca cgacgacacg
    17821 gcacgggacc gatccggcca ctgctacccc ccgaacttcc ggctcgactt gatcatcatc
    17881 atctcatcgg ccgacgcggg gtgaccatcc cggcggcccg aacacatacc cggcccggtc
    17941 ccgccatcgc accgccgcgc ggacgtcgcg ccaggcggcc gcgtactcgt ggaaggccac
    18001 ccgcaccagg ttgtagctgt cgatgttctt cgtcagcccg tacaccaccc gctccccctc
    18061 cggttcgaag gtgcggaaga gccggtccca gatgatgagg atgccgccgt aattgcggtc
    18121 caggtacacc tggttggagc cgtggtggac gcggtggtgc gagggcgtgt tgaagaacca
    18181 ctccaccggg cgccacagct tgtccacccg ctcggtgtgc aggaagaact ggtagacgag
    18241 gctgaccgcc tgctcgacca ggatcatcca cggcggcaca ccgagcagcg ccagcggcag
    18301 ccagaacggc agcccggtca tcggcgtcca ggtctggcgc agcgcggtgg agaggttgta
    18361 gcgcaggctg gagtggtgga ccacatggct cgcccacagc acccgtaccc ggtgatgggc
    18421 ccggtggtag gcgtagtagg ccaggtcgtc gccgaagaac agcagcagcc aggtccagcc
    18481 ggaggacggc gacagatgcc aggggacggc ggtgtacgcg gcggcgtaga ccacgatggt
    18541 cgccaccttc cacggcaccg cgatgacctg gctgcccgcg cccatggaca tgctggtgac
    18601 ggtgtcgcgc agctcgtacc cgcgctcgtc gtcgtccggc aggaagcggt acgacagcgc
    18661 ctccaccacg accagcagca cgaacgccgg gatcgcgtag accacggtgg ggatcatcgc
    18721 cgtgccccct tacgggcgcg gggcgcggcg ggcacgctgc gggtcagcag ctcacgggcc
    18781 agcagctcgg ccgcgccggc ctcgcgggcg gtgatgtgcc cggcgagccg ccgatgggcc
    18841 tcgacgtcga ggatctcgcc cgcgccgagg tcggcgggca cgtcggcgac cgggatcagt
    18901 ccgtcgacca ggctgttgaa ggccagcaga taggcgatgt tcccggagcc ctccacgatc
    18961 agccgccacc aggcgatgta ggtctcgtcc aggtcggtca gatcgggccc ggcctgggcg
    19021 tgcgcctcga cggccgcggc gatctcggcg gcggcccgcg cggagcagcg cagcgcgcac
    19081 agccgggcgg cgtccgcgcc gatgcaggcc cgcatctcca gcgcgtcgcg ggcgatgtcc
    19141 tgcacggtgg gcccgctgtc ggcggcggcg atgcccacgg cgagttccag accggcggtg
    19201 cgccgccagt ccagcacctg ggtacggccg ccatggctga cctcgaccag ccgggcctgc
    19261 tggaggcgtt tgacggcctc ccgtacggcg tgccggttca ccccgaactc ggccgccagt
    19321 tcccgctcgg cggtgagcgc gctgcccgcc ggcagcgccc cgccgagaat cctgtcccgc
    19381 aacagggcga agagctggtc ggagaccgcc tcgcgccgta tgtgtccctc agtcatggcg
    19441 atcagggtgg acgcggttcg tacagtggtc aactggttgg accagttttt ccgcgcgggc
    19501 ccgcggacat gtcggcgttc gtccggatcc gccaagcgtc gcttcgctcc gaggcgttgg
    19561 cgcgcggctc ccggccgccg tccgggtggc cgtgcgcgcg ccccggtctc gccccatgct
    19621 ggacgtgagg gggcggtacg gcggaggagg aagtggttgc gatgcagacc gttgtcgacc
    19681 tcacgcgctg ccaggggtac gcacagtgcg tgttcctcgc gccggacgtg ttcagactgc
    19741 acggcgagga agggctgctg tacgccccgg ccgtccccga cgatcaggtc gaacgggtgc
    19801 gccaggccgc cgcggcctgc ccggtgcagg ccattctcct cggggaagag gtgagcggcg
    19861 gtgcccgatg acctcacagg cggccggatc gtcgtcgtgg gcgcctcgct ggccgggctg
    19921 cgggccgcgg aggcgctgcg cgagcagggt ttcaccggct ccctgaccgt cgtcggggac
    19981 gagccccatc cgccgtacga ccgcccgccg ctgtccaagc aggtactgct gggcgtcgcg
    20041 cccgccgact ccaccgggct gccgatgcgc cgcgacccca aggcggaatg ggtgctcggt
    20101 gtaagggcca ccggcctgga cacgctgggc aagcgggtgc tgctcgacaa cggggagtcc
    20161 ctgccgtacg accgggtgct gatcgccacc gggacccgcg cccggccctg gccgaacccg
    20221 gcggaggccg cgctggacgg cgtgttcacc gtgcgcaccc gcgaggacgc ggcggggctc
    20281 gcggcggcgc tggacgcggg gccgcggcgg gtgctggtga tcggcggcgg gttcaccggc
    20341 tccgagatcg cctcggcctg ccgggagcgc ggtctggagg tcacggtcac cgagcgcggc
    20401 cccgcgcccc tggtcggcgc gctcggcggc accctgtcca agctcgcggc cgccatgcag
    20461 cgcaaccacg gcgtggacct gcgcaccggg gtgacggtga ccaggctgct cggcgagaag
    20521 accttcaccg gtgtggagct gtccgacggc aaccaggtgg acgcggatgt gtgcgtggtg
    20581 gcgctcggcg cggtgcgcaa tgtggagtgg ctcgcggact ccgggctcgc ggcgggcccg
    20641 cgcggactgg cctgtgacgc cgggtgccgg gccttcacca tgtacggcat cgtcaccgac
    20701 gacgtcttcg tggccggtga cgtctcccgc ttcccgcacc cgctcttcgg ctaccagctg
    20761 ctgtccctgg agcactgggg caacgcggtc acccaggccg aggtggccgc ccacaacatg
    20821 gtcaacccgg gaccgctgcg gcgcccgcac ctggccctgc cgacgttctg gtcgacccag
    20881 ttcgggctga acatcaagtc ggtgggggtg cccacctact ccgaccacgt ggtcatcgcg
    20941 cagggctccc tggaggcgcg gcggctcgcc atggtctacg gctaccgggg ccgggtcacc
    21001 gccgcggtca cggtcgacat ggccaagtcg ctcgactact accagcatct gatcgagacc
    21061 ggcgcgccgt tcccgccccc gccgggcgcc gccgaccggg cgctcgcggc cgagatcccg
    21121 atcccgtccg acgtaccgga cccgtcggtg ctctcgcacg gcccgacggt cgcactgacc
    21181 ggctatctgc cggaccgccg gctgacggtg gtatagcccg ccccgactcc gaggagccga
    21241 catggacccc ggcaccctgc tggccaggat caccgactac gccagccgcc ccgaccccta
    21301 tcccctgtac gcggagctgc gcgaggcagg aaccgtcgtc ccgcaggccg acggcagcct
    21361 gctgatcggc ggctatcacg aggtcgccgc gctgctgcac gatccgcgca tgagcgcgga
    21421 tccccgcacc cgcggcctgg agaccgccaa gccgccgttc ctgcgcctgg acgacccgga
    21481 gcaccaccgg ctgcgcaccc tggccatgcg gccgttcggc ccgccgcaca cgccgcaccg
    21541 ggtggacggg atgcgcaccg agatcgagaa catcaccaag gagctgctgg cgccgttcga
    21601 gtcgggtgga caggtcgatg tcgtggacga cttcgcctat ccgctgccgg tcacggtgat
    21661 ctgccggctg ctcggagtgc cgcacgagga cgaaccgctc ttccgggcct ggtcggacac
    21721 gctggtggcg tccgccgacg tacggccgga cgccagctcg gcaccgcgcg acgaggccga
    21781 acgggcccgc caggagatgg gcgggtacct ggtgggcctg gccgagcagc gccgggacga
    21841 cccgcgcgac gacctcctgt ccgcgttcgt ctccgagccc gaccccgagt tgcggctcag
    21901 ccaggaggaa ctggcccaga cggcggtgct gttgctgatc gccgggcacg agaccacggt
    21961 caacctcatc accaacgggg tgctgaccct gctgcgccat cccgaggagc tggaccggct
    22021 gcgccgcgaa cccgagctga tgccgagggc ggtggaggaa ctgctgcgct tcgaaccccc
    22081 ggtgcacatg cgcgagcgca tcccgctcgc cgacttcgat gtcgccggca ccacgctccc
    22141 gcgcggctcc tccgtgttcc tggccctggc cgcgggcaac cgcgacccgc gccgcttcac
    22201 cgatcccgac cgcttcgacc cggcccgcgc cgacaatgag cacctcggct tcggctccgg
    22261 catccacctc tgctatggcg ccccgctcgc ccggctggag gcgcagtccg cgctgacggc
    22321 gctgctgccc cggctgggca cggccgaact ggtcgaggac ccgccgccgt accggcagaa
    22381 cgcgatgctg cgggggccgc gccatctgac gctgaggttc tgacggctgt gatggcccga
    22441 acacctcccg gtggcggcgc ggggctgaga cgatcgggcc atggcagaga tcatcttgat
    22501 gtccgatccg aaggtcgccg ccgtgcccgt gcgggagtgc ggtgagcggc tggtggatgt
    22561 gcgccgtgac ggccggctgc cggtcgacgc gcgcaaggtg gacggggacg gtgcgttcgc
    22621 ccggctgcgg gagggtgtgt tcgaacggct gctcaaagca caggagtcgc tgcccgagg
//
