LOCUS       NZ_CP094483            21293 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces murinus strain JS029 chromosome.
ACCESSION   NZ_CP094483
VERSION     NZ_CP094483.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces murinus
  ORGANISM  Streptomyces murinus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Draft genome sequence of Streptomyces sp. JS029
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAR-2022) Agricultural Life Science, Sunchon National
            University, Jungangro 255, Suncheon, Jeonnam 57922, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-MAR-2021
            Assembly Method                   :: Unicycler v. 0.3.1
            Assembly Name                     :: JS029
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 164.82x
            Sequencing Technology             :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028753175.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 03:30:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,582
            CDSs (total)                      :: 7,481
            Genes (coding)                    :: 7,273
            CDSs (with protein)               :: 7,273
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 215
            CDSs (without protein)            :: 208
            Pseudo Genes (ambiguous residues) :: 0 of 215
            Pseudo Genes (frameshifted)       :: 110 of 215
            Pseudo Genes (incomplete)         :: 125 of 215
            Pseudo Genes (internal stop)      :: 20 of 215
            Pseudo Genes (multiple problems)  :: 41 of 215
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:08:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 85002
            Orig. end                         :: 106295
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP094483.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from National Institute of
            Biological Resources.
FEATURES             Location/Qualifiers
     region          1..21293
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21293
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21293
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11293](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11293)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            1128..1802
                     /locus_tag="ME763_RS00430"
                     /old_locus_tag="ME763_00425"
     CDS             1128..1802
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020132972.1"
                     /locus_tag="ME763_RS00430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00425"
                     /product="response regulator transcription factor"
                     /protein_id="WP_085568277.1"
                     /transl_table=11
                     /translation="MRVLLVEDEEDLRYVIEAGLRGAGYAVDAVGDWPDADVLLDLAPY
                     SCVVLDRMVPSGDTLDALRERRRRGWTTPVLCLTALNEVPDRVDGFHAGADDYLAKPFA
                     MVELVVRVGSLVRRAPERTPVRLRHGDVEMDEARREVRRAGILLSLTPKEYAVLRLLLL
                     HPEEVVTRSTLIEHCWDEMADPVSNVVDAVVAGLRRKLGPPAPIRTVRGHGFRFSGSAD
                     PV"
     gene            1799..2287
                     /locus_tag="ME763_RS37935"
     CDS             1799..2287
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS37935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_337999684.1"
                     /transl_table=11
                     /translation="MTGDHEGPRPAESRPRRAPRRGLLTRLLPRRSARTAGERRTPSPA
                     RRRLGRLQWRLTLAYTLITLAGVGALSWLVVRTDARSWQSAEYEDLHRRAAVAVSLIYY
                     TDAGIQLDGLYDDEATSAGAQVIVLQAHGGGGCGGSSPRMAPAWMSRRTRSTGSRTGR"
     gene            2239..3219
                     /locus_tag="ME763_RS00435"
                     /old_locus_tag="ME763_00430"
     CDS             2239..3219
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024970.4"
                     /locus_tag="ME763_RS00435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00430"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_337999685.1"
                     /transl_table=11
                     /translation="MDVEADAVDRIAHRAMTHDGTVSTRARTGAGDPVFLLALPYYQDQ
                     SQKTAGAVVVVGDPGRGRAEHRRLVVAVLSGSGLLVLLSAATGYVLSGRSMRPAWEALD
                     AQERLLADAAHELRTPVAVMRGSVDIADTDPGGLHSHLPRLRRATDRMTDVVDNILTRG
                     RLQATDTFRPVPLRLDQLVEQVCEELPVSRHTVTTFLDASVTTADPALVRIAVRNLLAN
                     ALRHGRTPGDPQDRAEVDVMVRGTAVTVADRGAGVDPEELPGLLERFRSEGGGTGIGLS
                     LVREVAAAHGGEVTVRRRPGGGSAFVLTLGPLQRPAGHRRAPRPS"
     gene            3281..4141
                     /locus_tag="ME763_RS00440"
                     /old_locus_tag="ME763_00435"
     CDS             3281..4141
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020132970.1"
                     /locus_tag="ME763_RS00440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00435"
                     /product="endo alpha-1,4 polygalactosaminidase"
                     /protein_id="WP_085568276.1"
                     /transl_table=11
                     /translation="MSKHSAVPFFRRRSTVVAGAVGVAAALGTGLTLSDVFADTPAAKA
                     APKVVLPAADATFDYQIGGPYTPAKGVTAVSRDRSAKPAKGLYNVCYVNAFQSQPESLS
                     WWTKNHPDLVLRGKGKRPVIDEDWDEALLDTSTADKRSRLATVVGAWIDGCAKSGFQAV
                     EPDNLDSYERSGGRLTKADNAAFAKLLAGRAHAAGLAVGQKNTADMLSDRTKIGFDFAV
                     AEECGQYNECGAYAKAYANRVFVIEYKDSGFDRACADFGPKLGIVRRDLDVSVRGSANY
                     TFRTC"
     gene            complement(4229..6217)
                     /locus_tag="ME763_RS00445"
                     /old_locus_tag="ME763_00440"
     CDS             complement(4229..6217)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088127.1"
                     /locus_tag="ME763_RS00445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00440"
                     /product="glycoside hydrolase"
                     /protein_id="WP_085568275.1"
                     /transl_table=11
                     /translation="MKARKIRKTRKKVVALSGALAVLGVVGTATAFGDGTGDRQRVEVH
                     GGRVTVPVAGGHTTVDTASLAVRAQADDGRGWQLSAPAADGLGPAGKVSVRGSEATWRY
                     PSTGFTVTAAARDGRLAVSVRSDRDATLNWPVTGADPATREMQIPRGEGLSVPVADRWW
                     NSSKAGLAGSEAGLSDGLTMPFWGTSLAGRHGSSYIAESDIGSTLTFASTGGRLRTEAR
                     HTFSAREDTGDYKITFALTDGSPVAAARDYRAWLLDHGGITTLRAKIAANPAVGKLVGA
                     FHAYTWGQARTTEGVRRLRDLGIDRMWLGYDADGSPMDAKAVALAERSGYLVGPYDSWA
                     NAQDPDSADTPVSKWPSPVWPDACVRDADGKPVTGFGGRGCYVSSEALRRAEPSKHYLA
                     DRTREMTANGADSYFLDVDAAGELFTDRSPAHPMTQAQDRRNRLERMAGLSGDRKLVLG
                     SESAGSWANGVVSFSHGSGTPVTDGLWALERDRATWGGYAPAGAPGVYFKPVHLPDDIA
                     KAMYDPRYRVPLYQTVLHDSVISTERWELSWSKLPDQSRTRALLAMLYNVPLNLVLDQS
                     ELDRHGKQIAALQRYFEPLHKAAATLPMTDFRRLTPDSLVQRTTFGDGTLTVTANFSTA
                     AHDGLPGGCVDAVIKGGKARHMCPPGL"
     gene            complement(6236..7681)
                     /locus_tag="ME763_RS00450"
                     /old_locus_tag="ME763_00445"
     CDS             complement(6236..7681)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010064041.1"
                     /locus_tag="ME763_RS00450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00445"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_085568274.1"
                     /transl_table=11
                     /translation="MRGLPWRRAGRRGGGWPRRRLRTRLTLAASAAVAVVVLGVCAAAF
                     LVIRQQLLHQLDLHLTQSARLAAQQYRQEPPGVVQGECRYLAAPACTQLVPACAVDDPA
                     GPYLLPVTGATRQVAAGTRGPFYSELRLAGHRARMLTTPLGAGRALQVAVRADTVDQGV
                     RQAAGLLGAVGAAGVVLAGVLGFWVSRTGLAPVARLTATAERIAATRDARHRIELPPKR
                     ADGDDEITRLAAAFNTMLGELEKSVTAQRRLVADASHELRTPLTALRANADLLARSDRL
                     TAAQRERAAGGLGRQLREVTVLVNDLIELAREEEPDPLVEDVRLASVVAHAVDAARDHW
                     PDVPFRLRIAHDTQTVTVAGVPARLSRLLSSLLDNAAKFSPPGRPVEVTLARTTGGTVL
                     EIRDHGPGIAAEDLPYVFDRFYRARTARALPGSGLGLAMARQIARAHHADLTAGQAPGG
                     GALFRLRIPDSAASDGLSQVSYP"
     gene            complement(7678..8388)
                     /locus_tag="ME763_RS00455"
                     /old_locus_tag="ME763_00450"
     CDS             complement(7678..8388)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889552.1"
                     /locus_tag="ME763_RS00455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00450"
                     /product="response regulator transcription factor"
                     /protein_id="WP_085568273.1"
                     /transl_table=11
                     /translation="MNSAGERVCAARILVVDDEPEVRYAVEDGLAVEGYDVRGAQDGPG
                     ALSAVAAWEPDAVVLDVMLPGLDGLAVCRRLRNLGDRTPVLVLTALGSVRERVDGLDAG
                     ADDYLVKPFALDELVARVRALLRRSAPAGPAAGTELSFADLVVDPVTRTGRRGARAVEF
                     SRTEFSLLELLLRHPGQVLPRSVILDRVWGRDFGPESNSLAVYVGYLRRKLEAGGEPRL
                     VHTVHGVGYRLDLP"
     misc_feature    8379..8397
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.34"
                     /tool="antismash"
     misc_feature    complement(8380..8398)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.16"
                     /tool="antismash"
     misc_feature    9075..9090
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.44"
                     /tool="antismash"
     gene            complement(9110..9985)
                     /locus_tag="ME763_RS00460"
                     /old_locus_tag="ME763_00455"
     CDS             complement(9110..9985)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004945512.1"
                     /locus_tag="ME763_RS00460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00455"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_085568272.1"
                     /transl_table=11
                     /translation="MTTETTPALSATIPAPATPYQEDIARYWNNEARPVNLRLGDVDGL
                     YHHHYGIGAVDHAALGDPEHREYEKKLIAELHRLESAQAELLLDHLGAITSDDTLVDAG
                     CGRGGSMVMAHRRFGCRVQGVTLSETQAEFGNGRARDLRIQDHVRSHVCNMLDTPFAKG
                     SVAASWNNESTMYVDLHDLFAEHSRILEVGGRYVTITGCWNPRYGQPSKWVSQINAHFE
                     CNIHSRREYLRAMADNRLVPQTIIDLTPDTLPYWELRATSSLVTGIEEAFIESYRDGSF
                     QYVLIAADRA"
     misc_feature    9987..10000
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.32"
                     /tool="antismash"
     misc_feature    9987..10001
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.02"
                     /tool="antismash"
     gene            complement(10001..11293)
                     /locus_tag="ME763_RS00465"
                     /old_locus_tag="ME763_00460"
     CDS             complement(10001..11293)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004945508.1"
                     /locus_tag="ME763_RS00465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00460"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_085568271.1"
                     /sec_met_domain="T1TS (E-value: 4.4e-69, bitscore: 232.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAPGPLGPTAPAPQQPTPSIRPAVSASTEPVTPPAPAPALAADP
                     GLGRILGGPTGLGTSSLSLARALKPPASDPHMAVAPAPAPEPDQVPPASSVSTSSVSSS
                     EGPVVPGLYHHPVPEPDPARVEEVSRRIKRWAEDEVQLYPEEWEGQFDGFSVGRYMVAC
                     HPDAPGIDHLMLATRLMVAENALDDCYCEDHGGSPIGLGGRILLAHTTLDHLHTTPEYA
                     PAWEESLGSDAPRRAYRSAMDYFVRAATPSQADRYRHDMARLHMGYLAEAAWAQTEYVP
                     EVWEYLAMRQFNNFRPCPTITDTVGGYELPADLHALPKMQRAIALAGNAATIVNDLYSY
                     TKELDSPGLHLNLPVVIARRDQLCERDAYLKAVEVHNQLMHAFEAAAAEVAAECPLPSV
                     LRFLKGVATWVDGNHDWHRTNTYRYSLPDFW"
     gene            complement(11464..12879)
                     /locus_tag="ME763_RS00470"
                     /old_locus_tag="ME763_00465"
     CDS             complement(11464..12879)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267883.1"
                     /locus_tag="ME763_RS00470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00465"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_085568270.1"
                     /transl_table=11
                     /translation="MTVDSSPEPRTVSAAPQQSLSTAAARNLATTTKSAPQMQEITSRW
                     LLRMLPWVETKGGAYRVNRRLRHTLGDGRIEFVQEGAAVRVIPRELGELALLRGFEDLD
                     ALTALADRCTQRDFAAGEVLVERGTPADRIHMIAHGRVSQTGHGQYGAEVALAVLADGE
                     HFGEEALLDGDSRHAYTATAQTSGTLLTLSRADFAAVHDSAPSLRTHIERFSSTTRKRQ
                     NKYGEAEIAMSAGHVGEAELPHTFVDYELNPREYELSVAQTILRVHTRVADLYNGPMNQ
                     TEEQLRLTVEALRERQEHELINNPEFGLLHNADFKQRIQPHSGPPTPDDMDELLTRRRG
                     TKFFLAHPRTIAAIGRGFTACGLYPDHVDVGGQTVPAWRGVPILPCNKIPISEEQTSSI
                     IAMRTGEENQGVIGLWQTGLMEEHEPGLSVRFMGINEQAVTSYLVSMYYSAAVLVPDAL
                     GVLENVHIARRRD"
     misc_feature    12838..12852
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.6"
                     /tool="antismash"
     misc_feature    complement(13045..13058)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.87"
                     /tool="antismash"
     misc_feature    complement(13047..13062)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.06"
                     /tool="antismash"
     misc_feature    complement(13048..13061)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.54"
                     /tool="antismash"
     misc_feature    complement(13051..13060)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.77"
                     /tool="antismash"
     misc_feature    13055..13073
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.92"
                     /tool="antismash"
     gene            complement(13235..13755)
                     /locus_tag="ME763_RS00475"
                     /old_locus_tag="ME763_00470"
                     /pseudo=""
     CDS             complement(13235..13755)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669381.1"
                     /locus_tag="ME763_RS00475"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00470"
                     /product="DinB family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNGHVSESIPSGEVGTLLRVLDGQRRHVLGILDGLDPKDLRRPVL
                     PSGWHCLGMVQHLTLDVERFWFRAVVAGDETVVRGLTSGDAAWRVAPDTPAADVLERYR
                     RGAERADAVITTTPTDAPPAWWPRDLFGEPHLHTLRDVLLHVITETACQPATSTRPVNS
                     STAAAGWSSP"
     gene            14244..14501
                     /locus_tag="ME763_RS00480"
                     /old_locus_tag="ME763_00475"
     CDS             14244..14501
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS00480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ME763_00475"
                     /product="hypothetical protein"
                     /protein_id="WP_085568268.1"
                     /transl_table=11
                     /translation="MHQGAAGQRTWYTTRSTTVCTKVRRGTETYRRVIHQERWCVMLDD
                     VGGKRSRDRVWYQVSRNTYTDTQVRRSGSKVTIEPERDGC"
     gene            complement(14701..15321)
                     /locus_tag="ME763_RS00485"
                     /old_locus_tag="ME763_00480"
     CDS             complement(14701..15321)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192046.1"
                     /locus_tag="ME763_RS00485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00480"
                     /product="hypothetical protein"
                     /protein_id="WP_085568938.1"
                     /transl_table=11
                     /translation="MAVHEHSHRHPGLRLSFRNDRTGTALAVSAGIDTHTRQARALASL
                     RILTGFVFLWAFLDKTFGLGYATASGKAWIDGVSPTKGFLGSVAVGPLRSTFHAWAGAG
                     WADWLFMLGMLGIGAAVTAGVALRPAAVAGTAMMALMWAAEWPPARHLADGSPSMSTNP
                     FADYHLIYAVALIAVAAVGAGTTWGLGRWWAGLPVVRDHAWLR"
     misc_feature    15552..15568
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.6"
                     /tool="antismash"
     gene            15699..16637
                     /locus_tag="ME763_RS00490"
                     /old_locus_tag="ME763_00485"
     CDS             15699..16637
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006379332.1"
                     /locus_tag="ME763_RS00490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00485"
                     /product="L,D-transpeptidase"
                     /protein_id="WP_085568937.1"
                     /transl_table=11
                     /translation="MGASACGGGSGNGSNTVGGDAKAPGKSAPSASASPTKPAGPPMLL
                     DTITPQSGTTVGVAMPISVVFTDPVAAKARATVEKHMKVSTSTPVAGAWHWFGDKRADW
                     RPKTFWPSGTKVKIDADMEGVSNGAGRYGVHDYTHTFTIGDDVRADVSVTGHTMKVTRD
                     GKLVRTLSINAGSPQYPTWNGIMAVIDKQEKVHMTSCSVGISCDKGSPNYYDLTLPWDV
                     HLTQSGTYVHYSTGDPTPGGGSARGSHGCVHLSLSDAKWFYGQVKQGDPVTITGSSRAK
                     ADPDNGYADFNLDWTQWLAGSASGEGTTSAL"
     gene            complement(16823..18505)
                     /locus_tag="ME763_RS00495"
                     /old_locus_tag="ME763_00490"
     CDS             complement(16823..18505)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (52-452). E-value: 6.1e-73.
                     Score: 237.7. Matches aSDomain:
                     nrpspksdomains_ME763_RS00495_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192637.1"
                     /locus_tag="ME763_RS00495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00490"
                     /product="class I adenylate-forming enzyme family protein"
                     /protein_id="WP_085568267.1"
                     /sec_met_domain="AMP-binding (E-value: 2.9e-76, bitscore:
                     255.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVAPATLPAARGGHLAWTSRAGVPFPDLVPRARRLAWVSEGLCP
                     DADLYTLFTARVRAHPDRAALVDDAGTLTYAALGAEVRRVAALFAGSGLAAGDVVALRL
                     PDGRDAVAAELAVYALGAVALPLPPSGDDRDTRALLARSRARAAVLASAEQIRALTDLP
                     HLVTRYVPGPDRTGALGLHPPRPRAPEPWRPGPVDPYGPARILVSSGSETEPKMVAYSH
                     HALAGGRARYVRALHPDPAVPARHLVLVPLASSFGSLGTPVTLAVLGGTLIVPSRFDPA
                     GALRLIAEHRPTHLFAVPTMLRRIADLPARPGEDTSSLRAVVSSGAALPPAVAEACRRR
                     FGRPVVTVYGSSDGVNCHTAGESRPTGDSVGTPDPKVARIRITGPDGGPLPTGQSGQIE
                     ALGPMTPLCYVNSPELNARYRTPDGWVRTGDLGRLDEHGRLHVLGRLKRIVVRGGLNIS
                     LAEVEHELGGHPSVAEAVCVPVPDPDLGERLCACVRPAPGTPAPTPADLTEHLLSRGLG
                     RRKHPELLLLVDEMPLGPTGKVCYRTLTAWAARQERNRSLGPR"
     aSDomain        complement(17150..18349)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ME763_RS00495_AMP-binding.1"
                     /evalue="6.10E-73"
                     /label="ME763_RS00495_AMP-binding.1"
                     /locus_tag="ME763_RS00495"
                     /protein_end="452"
                     /protein_start="52"
                     /score="237.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FTARVRAHPDRAALVDDAGTLTYAALGAEVRRVAALFAGSGLAAG
                     DVVALRLPDGRDAVAAELAVYALGAVALPLPPSGDDRDTRALLARSRARAAVLASAEQI
                     RALTDLPHLVTRYVPGPDRTGALGLHPPRPRAPEPWRPGPVDPYGPARILVSSGSETEP
                     KMVAYSHHALAGGRARYVRALHPDPAVPARHLVLVPLASSFGSLGTPVTLAVLGGTLIV
                     PSRFDPAGALRLIAEHRPTHLFAVPTMLRRIADLPARPGEDTSSLRAVVSSGAALPPAV
                     AEACRRRFGRPVVTVYGSSDGVNCHTAGESRPTGDSVGTPDPKVARIRITGPDGGPLPT
                     GQSGQIEALGPMTPLCYVNSPELNARYRTPDGWVRTGDLGRLDEHGRLHVLGRLKRIVV
                     R"
     gene            complement(18502..20280)
                     /locus_tag="ME763_RS00500"
                     /old_locus_tag="ME763_00495"
     CDS             complement(18502..20280)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1189: L-carnitine dehydratase/bile acid-inducible"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006140156.1"
                     /locus_tag="ME763_RS00500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00495"
                     /product="CoA transferase"
                     /protein_id="WP_085568266.1"
                     /transl_table=11
                     /translation="MSPRTVVRPVVAGAVADRLLRHTAPGVPQVRPTLDWAGPVGMELP
                     DERAVQAACGLMHIHGRATGGPAPLAVDYASVVAGVLAAQGATAAGIGRARGLDLREVR
                     TSVAQGALLAVGQYLAAATAREADGPPATAGPEPCAGGLATLETADGAHVELETLDPSA
                     WREFWARLGVPSALAGRGWLPFQQRFATAVCPLPEELRAAARRRTLPDLRAAAYDTGVS
                     LLTLGADPDPAVHPEPWRLTPAPAVHPEHRLPAPAVTPVPRRRTSGPAHPAPDMPAPRS
                     GGAPPLPLAGLRVVESTRRVQGPLAGHVLGMLGAEVIRIEPPGGDPMRWLPPLARDTSA
                     RFTALNAGKRVVEADLTTARGRETVRALAAEADAFVHNWAPGKAARLGLDAADLLSDRP
                     ALVYAWASGFGDTLGDRPPLGTDYLAQVHSGLAAAVRPADEPPAPSLMTLTDVLGGLVC
                     AQGVLAALAHRARTGRGGRVDSSLVSAAALIPRPAHRVRWTAPDRPVRTADGHLYLGPK
                     ARANPEAVHRLLGRAEESALTTDEWTHRLAEAGLTATPVHTDLAALADDPAFKAAVAPP
                     DPLIGHARPHAPWEFA"
     misc_feature    complement(20224..20226)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(20277..21086)
                     /locus_tag="ME763_RS00505"
                     /old_locus_tag="ME763_00500"
     CDS             complement(20277..21086)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019979831.1"
                     /locus_tag="ME763_RS00505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00500"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_085568265.1"
                     /transl_table=11
                     /translation="MAPPAPARVVFGNGTAHSRDQHRCLEAAYDPVTLPRLAAAGVGPG
                     WHCLEIGAGGGSIARWLARRVAPGGSVLATDRDPRDLVPGPQLKVAALDVARDPLPEAA
                     YDLIVARLVLQHVPTRAAVLPRLVRALRPGGLLQIDEIDASYEPPLLTPDAAAEELYLR
                     FLRAKSAAMRAAGGDPHWGRAVPGALRAAGLTGIDVHLHIGVRHAQDPGLGLQSNHTRN
                     LRDRLVEQGMTDEELDRVRQLMRDPGFRAASSVFYSVQGRRPGGEGG"
ORIGIN
        1 atctgttctc ggcgacggac ctgccggagt tcctgaccgt acggcaggat ggccgggaga
       61 ccgccgaggc caccgcggcc gggctggacc gggccggccg cgactatatg agcgggctgg
      121 gccggctgcg caggctgacg ccgttcgcca gggatctggc agccggggag cgcaggtcac
      181 gggtgctgct cggcgatctg acggcggagt accaggcggc ggcgatcacc ccctactggg
      241 agcggatcga tctgctggtg gcggcggaac accggtaccg ggcacggcag ttggccaccg
      301 ggggcctgga cgaggtactg accacactgc gcccggacat ccgatgggag cggcccgtgc
      361 tgaccctgcc gatgtcaccc tgtctgaccg aggtcgacct gggcgggcgc ggcctgctgc
      421 ttcagccggc cgtcttcgcg gccggacggc tggtgatcgc cggtttcgag gccccgcagg
      481 aacagccggt gctcatctat ccgataccgg gcgaccggcg gctgctcatg gacgaccagg
      541 tcagcgcgcc gcccgcgctg acgaacctgc tgggccggac ccgggccgcc gcgctctgca
      601 ccctggccgc gcgcggcccc ctgagcacca ccgaactggc caccgccctc ggcatctccc
      661 cggccaccgc cagccaacac gccagcatcc tggccgactc cggcctcacc accaaggagc
      721 ggcagggcgg gacggtggtg caccacctca cgctgttggg cgaggtgctg ttgaagggtg
      781 gggtggcggg tgcggcgaag ggggtgtcgc ggttgttgat gggtggggag gggtgagttc
      841 ggggggtacg ggagggcttc gcttgtgatc gcggaggcgg gcagggggtt gtccggttcg
      901 gtgcccgggt aggcggtggt gctgacaccg gccgttcggg cgtcgaaggc cggcttcgac
      961 gcagcgggcc cggtggagga tcgaggttcc cggctcggtc acccgggcgc cgtcggattt
     1021 tcttcaggtg tctactatgt cgtcctcgcc gacgccccac ccccctccgg cgaaccggcg
     1081 cgcccctccc ccctgcgccg ccctagcccc aaggacgagt cagaaccatg cgtgtgctcc
     1141 tggtcgagga cgaagaagat cttcggtatg tcatcgaggc agggctgcgg ggtgccgggt
     1201 acgccgtgga cgctgtcgga gactggccgg acgcggatgt tctgctcgac ctcgcgccgt
     1261 acagctgtgt ggtcctggat cgcatggtgc cgtccgggga cacgctggac gcgctccggg
     1321 agcggaggcg tcgggggtgg acgacgccgg tgctgtgtct gacggcgctg aacgaggtac
     1381 cggaccgggt cgacggcttt cacgcggggg cggacgacta cttggcgaag ccgttcgcga
     1441 tggtggagct ggtggtgcgg gtgggcagtc tggtccgccg ggcaccggag cggacgcccg
     1501 tgcggcttcg ccatggcgac gtcgagatgg acgaggcccg tcgcgaggtg cgcagggccg
     1561 ggatcctgct gtccctgacg cccaaggagt acgcggtgct gcgcctgctg ctcctgcacc
     1621 ccgaggaggt cgtcacccgc tcgacgctga tcgagcactg ctgggacgag atggccgacc
     1681 ccgtctcgaa cgtggtggac gcggtcgtgg cggggctgcg gcgcaagctc ggaccgcccg
     1741 cgccgatccg gaccgtgcgc gggcacgggt tccggttctc cggcagcgcg gatccggtgt
     1801 gacgggcgac cacgaagggc cgcggccggc ggagagccgt ccgcgccggg cgccacggcg
     1861 cggactcctg acccggctcc tcccccggcg aagcgcccgt accgccggag agcggcgcac
     1921 cccgtccccg gctcgccgcc gtctcggccg gctccagtgg cggctgacac tggcgtacac
     1981 gctcatcacg ctggccgggg tgggcgcgct gtcgtggctg gtggtccgta cggacgcgcg
     2041 gtcctggcag tccgccgagt acgaggacct gcaccggcgg gcggcggtgg ccgtgtcgct
     2101 gatctactac accgacgcgg ggatccagct ggacggcctg tacgacgacg aggcgaccag
     2161 cgcgggcgcg caggtgatcg tgctccaggc gcacgggggg ggcggctgcg gcggctcttc
     2221 acctcgcatg gccccggcat ggatgtcgag gcggacgcgg tcgaccggat cgcgcaccgg
     2281 gcgatgaccc acgacggcac ggtgagcacc cgggcccgga ccggcgcggg cgatcccgtg
     2341 ttcctgctgg cgctgccgta ctaccaggac cagtcgcaga agacggccgg cgcggtggtg
     2401 gtggtcggcg atccggggag agggcgggcc gagcaccggc gtctggtggt ggcggtgctg
     2461 tccggctcgg gcctgttggt gctgctgtcg gcggcgaccg gatacgtgct gtccgggcgg
     2521 agcatgcggc ccgcctggga ggcgctggac gcgcaggagc ggctgctcgc ggacgcggcg
     2581 cacgagctgc gtaccccggt ggcggtgatg cgcggctcgg tggacatcgc ggacaccgat
     2641 ccgggaggcc tgcactcaca tctgccgcgg ctgcggcggg ccacggaccg gatgacggac
     2701 gtggtcgaca acatcctcac ccgcggacgg ctccaggcga cggacacctt ccggccggtg
     2761 ccgctgcgcc tcgaccagct ggtcgagcag gtctgcgagg aactgccggt ctcccggcac
     2821 acggtgacga cctttctgga cgcgtcggtg acgacggcgg atccggcgct ggtgcggatc
     2881 gcggtacgca atctgctggc caacgccctg cggcacgggc ggacgccggg agatccacag
     2941 gaccgcgccg aggtggacgt catggtgcgc ggtacggcgg tgacggtggc ggaccggggc
     3001 gccggggtgg acccggagga gctgcccggt ctgctggagc ggttccgctc cgagggcggt
     3061 ggcacgggca tcgggctgtc gctggtgcgg gaggtcgccg ccgcgcacgg cggggaggtg
     3121 acggtccggc gcaggccggg cggcggttcg gccttcgtgc tgacgctggg gccgctccag
     3181 cggccggccg ggcaccgccg ggctccgcgt ccctcatgaa atcctcatgg tcggcggctc
     3241 aggatgtgcg ggtcagtacg aactttgcac aggagtccgt gtgtcgaagc actccgctgt
     3301 acctttcttc cgccgcagaa gcaccgtcgt cgccggtgcg gtcggggtcg ccgccgctct
     3361 cgggacgggg ctgacgctgt ccgacgtctt cgcggacacc ccggccgcga aggcggcgcc
     3421 gaaggtggtg ctccccgcgg ccgacgccac gttcgactat cagatcggcg gcccgtacac
     3481 cccggccaag ggcgtcaccg ccgtgtcccg cgaccggtcc gccaagcccg ccaagggcct
     3541 ctacaacgtg tgctacgtga acgcgttcca gtcccagccc gagtcgctga gctggtggac
     3601 gaagaaccat cccgatctgg tcctgcgggg caagggcaag cgtccggtga tcgacgagga
     3661 ctgggacgag gcgctgttgg acacgtccac ggccgacaag cgctcccgtc tcgccacggt
     3721 cgtcggagcg tggatcgacg gctgtgccaa gagcgggttc caggccgtcg agccggacaa
     3781 cctcgactcc tacgagcgtt ccggcggccg gctgacgaag gcggacaacg cggccttcgc
     3841 gaagctgctg gccggccgcg cccacgccgc cggtctcgcc gtcgggcaga agaacacggc
     3901 cgacatgctc tcggaccgca cgaagatcgg cttcgacttc gccgtcgccg aggagtgcgg
     3961 gcagtacaac gagtgcggcg cgtacgccaa ggcgtacgcg aaccgtgtct tcgtgatcga
     4021 gtacaaggac agcggcttcg accgcgcctg cgcggacttc ggcccgaagc tcggcatcgt
     4081 ccggcgcgac ctggacgtct cggtccgcgg ctccgcgaac tacaccttcc gcacctgctg
     4141 accggccccg gtccgccagc cctccaagct gccgagccac aacggtccgc cggacccgtg
     4201 cggtcacagg cccggcggac cccggcgctc acagacccgg cggacacatg tgccgggcct
     4261 tgccgccctt gatcaccgcg tcgacgcatc cgccgggcag gccgtcgtgc gccgcggtgg
     4321 agaagttggc ggtcacggtc agggtgccgt cgccgaaggt cgtccgctgc accaggctgt
     4381 ccggcgtcag acggcggaag tcggtcatcg gcagggtggc cgcggccttg tgcagcggct
     4441 cgaagtaccg ttgcagcgcg gcgatctgct tgccgtgccg gtccagttcg gactggtcga
     4501 gcaccaggtt gagcggcacg ttgtacagca tcgccagcag cgcgcgggtg cggctctggt
     4561 ccggcagctt cgaccaggac agctcccagc gctcggtgct gatcaccgag tcgtgcagca
     4621 ccgtctggta cagcggcacc cggtacctcg ggtcgtacat cgccttggcg atgtcgtccg
     4681 gcaggtggac gggcttgaag tagaccccgg gcgcgcccgc gggcgcgtaa ccgccccagg
     4741 tggcccggtc ccgctccagc gcccacagtc cgtcggtgac gggcgtgccg gagccgtggc
     4801 tgaaggacac caccccgttc gcccaggaac cggcgctctc cgaaccgagg accagcttcc
     4861 ggtcgccgga cagccctgcc atgcgctcca gccggttgcg gcggtcctgc gcctgggtca
     4921 tcgggtgcgc cggggaccgg tcggtgaaca gttcgccggc cgcgtccacg tcgaggaagt
     4981 agctgtcggc gccgttggcg gtcatctccc gggtccggtc ggcgagatag tgcttcgacg
     5041 gctcggcgcg ccggagcgcc tcggagctga cgtagcagcc gcgcccgccg aaaccggtga
     5101 ccggcttgcc gtccgcgtcc cgtacgcagg cgtccggcca caccggggac ggccacttcg
     5161 agaccggggt gtcggccgag tccgggtcct gggcgttggc ccaggagtcg tacggtccca
     5221 cgaggtagcc ggagcgttcg gcgagggcga cggccttggc gtccatgggc gagccgtcgg
     5281 cgtcgtagcc gagccacatc cggtcgatgc cgaggtcccg cagccggcgc acgccctcgg
     5341 tggtgcgtgc ctggccccag gtgtaggcgt ggaaggcgcc caccagcttg cccaccgcgg
     5401 ggttcgcggc gatcttcgcg cgcagggtgg tgatgccgcc gtggtcgagc agccaggcgc
     5461 ggtagtcgcg ggcggcggcc accggggagc cgtcggtgag cgcgaaggtg atcttgtagt
     5521 cgccggtgtc ctcacgcgcc gagaacgtgt gccgcgcctc ggtgcgcagc cggccgccgg
     5581 tggaggcgaa cgtcagtgtg ctgccgatgt cggactcggc gatgtagctc gacccgtgcc
     5641 gtccggcgag gctggtgccc cagaacggca tggtcaggcc gtcggagagg cccgcctcgc
     5701 tgccggcgag cccggccttc gacgagttcc accagcggtc ggcgaccggc accgacaggc
     5761 cctcgccgcg cggtatctgc atctcccggg tggccgggtc ggcgccggtc accggccagt
     5821 tcagcgtggc gtcgcggtcg gagcgcaccg acaccgcgag gcgtccgtca cgggcggccg
     5881 cggtcacggt gaaacccgtc gacggatagc gccaggtggc ctcgctcccg cgcaccgaca
     5941 ccttccctgc ggggcccagg ccgtcggccg ccggcgccga gagctgccag ccgcggccgt
     6001 cgtcggcctg tgcgcgcacg gccagggacg cggtgtccac cgtcgtgtgt ccgccggcga
     6061 cgggcacggt cacccggcct ccgtgcacct cgacgcgctg ccggtcaccg gtgccgtcgc
     6121 cgaacgcggt ggccgtgccg accacgccga gcaccgcgag ggcgccgctc agcgcgacga
     6181 ccttcttcct ggtcttcctg atcttcctcg ccttcatggt ccgtcactgt ggtgctcagg
     6241 gataagagac ttgtgagagg ccgtcggacg cggcggagtc cggtatccgc agccggaaga
     6301 gcgcgccgcc gccgggcgcc tgacccgcgg tgaggtcggc gtggtgggcg cgggcgatct
     6361 ggcgggccat ggcgagaccg agcccggagc cgggcagggc gcgggccgtg cgggcccggt
     6421 agaagcggtc gaagacgtag ggcaggtcct cggcggcgat gccgggcccg tggtcgcgga
     6481 tctccaggac cgtgccgccc gtcgtacggg ccagggtgac ctcgacgggg cggccgggcg
     6541 gactgaactt ggccgcgttg tcgagcaggc tcgacagcag ccgggacagc cgcgccggta
     6601 cgcccgccac cgtcacggtc tgcgtgtcgt gggcgatccg cagccggaag ggaacgtccg
     6661 gccagtggtc gcgggccgcg tcgaccgcgt gggcgacgac cgaggccagt cggacgtcct
     6721 ccaccagcgg gtccggctcc tcctcgcggg ccagttcgat caggtcgttg acgaggacgg
     6781 tgacctcgcg cagctggcgg ccgagcccgc cggccgcccg ttcgcgctgt gccgcggtca
     6841 gccggtcgga gcgggcgagc aggtcggcgt tggcgcgcag cgcggtgagc ggggtgcgca
     6901 gttcgtggga ggcgtcggcg accagccggc gctgggcggt cacggacttc tccagttctc
     6961 cgagcatggt gttgaaggcg gcggcgagcc gggtgatctc gtcgtcgccg tccgcccgct
     7021 tcgggggcag ctcgatgcgg tggcgggcgt cgcgggtggc ggcgatgcgt tccgcggtcg
     7081 cggtcagccg ggcgaccggg gcgaggccgg tccgggagac ccagaagccg agcaccccgg
     7141 ccaggacgac accggccgcg ccgacggcac cgagcagtcc ggcggcctgc cgtacccctt
     7201 ggtcgacggt gtcggcgcgc accgcgacct ggagggcgcg gcccgccccg aggggagtgg
     7261 tcagcatccg ggcgcggtgg ccggcgaggc ggagttcgct gtagaagggg ccgcgggtac
     7321 cggcggccac ctggcgggtg gcaccggtga cgggcagcag ataggggccc gccggatcgt
     7381 ccacggcgca ggcgggcacc agttgggtgc aggccggggc ggcaaggtac cggcattccc
     7441 cctggacgac gcccggcggt tcctgccggt actgctgggc ggccagccgc gcggactggg
     7501 tcagatgcag gtccagctgg tgcagcagtt gctgccggat cacgaggaac gcggcggcgc
     7561 agacccccag cacgacgacg gcgacggcgg ccgaggcggc gagggtcagc cgggtgcgca
     7621 gccggcggcg cggccacccg ccgcccctcc gtccggcccg gcgccagggc aggcccctca
     7681 tggcaggtcc agccggtagc cgacgccgtg cacggtgtgc accagccggg gttcgccgcc
     7741 ggcctccagc ttgcgccgca ggtaaccgac gtacacggcg agcgagttgg actccggtcc
     7801 gaagtcgcgg ccccacaccc ggtccaggat cacgcttctc ggcagcacct ggccggggtg
     7861 ccgcagcagc agctccagca gggagaactc ggtacggctg aactcgacgg cgcgggcgcc
     7921 gcgccgcccg gtgcgggtga ccgggtccac gacgaggtcg gcgaacgaca gctccgtccc
     7981 ggccgcgggc ccggcgggtg cggagcggcg cagcaaggcc cgtacacgtg ccacgagttc
     8041 gtccagggcg aagggtttga ccaggtagtc gtcggcgccc gcgtcgaggc cgtcgacccg
     8101 ttcgcgtacc gagccgaggg cggtgaggac caggacgggg gtgcggtcgc ccaggttccg
     8161 cagccgtcgg cagaccgcga gcccgtcgag gcccggcagc atcacgtcga ggaccacggc
     8221 gtcgggttcc cacgcggcca cggcggacag cgcgccgggc ccgtcctgcg ccccgcggac
     8281 gtcgtagccc tccaccgcga ggccgtcctc gacggcgtac cgcacctcgg gctcgtcgtc
     8341 gacgaccagg atcctcgccg cgcacacccg ctcaccagca ctgttcatac ggccagcttg
     8401 ccaaacacgg cccgaaaggc ggcgcggggg ccgctgccct acccgacggg tgccaggggt
     8461 tcgtctcgta gcactgcccg agcagtgccg tgataccggg atcgacgggc agcacttgcg
     8521 tggcctacgt gggtgctcag cggtagtcct cggggggccc tgcatccagg cgttgatctt
     8581 gtcccgggtt ccggtgagct ggtcctggtg cttcttcagg ttcccgaagg aggtgtcgtc
     8641 gcccagttcg ccccacagtt tcgcgagccg ggcgagaggc tccttgaagt ggcccgggcc
     8701 ctgggggtcc gctctcatcg ccttgtcgag accggtgagt tcatcgtgca ggcggcccag
     8761 gaaatacgcg cagttcccgg gggtcgtaca gccgtcgttg tacgtggcct gcagtccggc
     8821 gaacgcgtcg cggaccttct ccacgtcctg tggcggttcc gtcgcgttcg cgggggccga
     8881 ctcctcggtc ggggtggccg gggccgtcgt acggatgtcg tgggagggcg gtgatctgtc
     8941 gcgggcggat gcgttgatca tgccgtccac gacactcctg cggtcgcgcc ggttgcaccg
     9001 cccggcctcc gtggcagggt gcgacgccgt gagcagtgcg gtcagggcgg ggcccggagg
     9061 tggcgggcgg gtccctgacc gctttgtcgg ctgcggagtc gaccggggct caggcgcggt
     9121 cggcggcgat caggacgtac tggaaggagc cgtcccggta ggactcgatg aaggcctcct
     9181 cgatgccggt gaccagtgag gaggtggccc gcagctccca gtagggcagg gtgtcggggg
     9241 tcaggtcgat gatcgtctgg ggcacgagcc ggttgtcggc catggcgcgc aggtactcac
     9301 ggcgggagtg gatgttgcac tcgaagtggg cgttgatctg ggagacccac ttggacggct
     9361 ggccgtaacg cgggttccag cagccggtga tcgtcacata ccggccgccc acctccagga
     9421 tgcgggagtg ctccgcgaac agatcgtgca ggtcgacgta catcgtggac tcgttgttcc
     9481 acgaggcggc gacactgccc ttcgcgaagg gggtgtccag catgttgcag acgtgggagc
     9541 ggacatggtc ctggatacgg aggtcccgcg cgcgcccgtt gccgaactcg gcctgcgtct
     9601 cggacagggt gacgccctgc acccggcagc cgaaccggcg gtgggccatc accatcgagc
     9661 cgccgcgccc gcagccggcg tccacgaggg tgtcgtcgct cgtgatggca ccgaggtggt
     9721 ccagaagcag ctccgcctgg gcggactcca gccggtgcag ctcggcgatg agcttcttct
     9781 cgtactcgcg gtgctccggg tcgccgagcg cggcgtggtc gacggcgccg atgccgtagt
     9841 ggtggtggta aaggccgtcc acgtcaccga ggcgcaggtt caccggcctc gcctcgttgt
     9901 tccagtaccg ggcgatgtcc tcctggtagg gggtcgccgg ggccgggatc gtcgcggaga
     9961 gcgcgggggt cgtttccgtg gtcacaggaa tatccgttcg ttaccagaag tcgggcaggc
    10021 tgtagcgata ggtgttggtg cggtgccagt cgtggttgcc gtcgacccag gtggccacgc
    10081 ccttgaggaa gcgcagcacg ctgggcaggg ggcactccgc cgcgacctcg gccgcggcgg
    10141 cctcgaaggc gtgcatgagc tggttgtgga cctcgacggc cttcaagtag gcgtcgcgtt
    10201 cgcagagttg atcgcgccgc gcgatcacca ccggcaggtt cagatgcagg ccggggctgt
    10261 cgagttcctt ggtgtaggag tagaggtcgt tgacgatggt ggccgcgttg ccggcgaggg
    10321 cgatggcccg ctgcatcttc ggcagggcgt gcagatcggc gggcagttcg tagccgccga
    10381 cggtgtcggt gatggtcggg caggggcgga agttgttgaa ctggcgcatc gccaggtact
    10441 cccacacctc gggcacgtac tcggtctgcg cccaggcggc ctcggccagg tagcccatgt
    10501 gcagccgggc catgtcgtgc cggtagcggt cggcctggga gggtgtggcg gcgcggacga
    10561 agtagtccat cgcgctgcgg tacgcccgcc gcggggcgtc ggagccgagc gactcctccc
    10621 acgccggggc gtactccggt gtggtgtgga ggtggtcgag cgtggtgtgc gcgaggagga
    10681 tgcggccgcc gaggccgatg ggcgagccgc cgtggtcctc gcagtagcag tcgtcgaggg
    10741 cgttctccgc gaccatcagc cgggtggcga gcatcagatg gtcgatgccg ggggcgtcgg
    10801 gatggcaggc gaccatgtag cgcccgacgg agaagccgtc gaactggccc tcccactcct
    10861 cggggtagag ctggacctcg tcctcggccc agcgcttgat ccggcggctc acctcctcga
    10921 cacgggcggg gtcgggctcc gggacggggt ggtggtagag gccggggacg accgggcctt
    10981 cggaggagga gacggaggaa gtggagacgg aggaggcagg gggtacctgg tcgggctccg
    11041 gtgccggagc cggtgccacc gccatgtgcg ggtccgaggc cggcggtttg agggcgcggg
    11101 ccagggagag tgaggacgtg cccaggccgg tcggtccgcc gaggatccgc cccaggccgg
    11161 ggtcggcggc gagggcgggg gcgggggcgg gcggcgtgac cggttccgtg gaggcggaga
    11221 cggccggccg gatcgagggc gtgggctgct gcggtgcggg ggcggttggt ccgaggggcc
    11281 cgggagcggg catctgcgac tccttgctgc ggcggcggag ggcgaactcg tgctgcgtgg
    11341 ggcggagtcg gcggcctcct ccgcgaaacg gttcctctgg tcccgcccgg ttccgcccgg
    11401 ttccgcccgg ttccgcccgc gggcgatgta cgcgtcaatc ccacctacgg gctacctacg
    11461 cgttcagtcc cgcctgcgag cgatgtgcac gttctccagc acgccgagcg cgtcggggac
    11521 gaggactgcg gcggagtagt acatgctgac gaggtaggag gtgaccgcct gctcgttgat
    11581 gcccatgaag cgcaccgaca ggcccggctc gtgctcctcc atcaggcccg tctgccacag
    11641 gccgatgact ccctggttct cctcgcccgt gcgcatcgcg atgatggagc tggtctgctc
    11701 ctcgctgatc gggatcttgt tgcagggcag gatcgggacc ccgcgccagg ccgggaccgt
    11761 ctggccgccg acgtcgacat ggtccgggta gagaccgcag gcggtgaacc cgcggccgat
    11821 cgcggcgatc gtcctcgggt gggcgaggaa gaacttggtg ccgcgacggc gggtgagcag
    11881 ttcgtccatg tcgtccgggg tcggcggccc ggagtgcggc tggatgcgct gcttgaagtc
    11941 ggcgttgtgc agcaacccga actcggggtt gttgatgagc tcgtgctcct ggcgctcccg
    12001 caacgcctcg accgtgagcc ggagttgctc ctcggtctgg ttcatcggcc cgttgtagag
    12061 gtcggcgaca cgggtgtgga cgcgcaggat ggtctgcgcg acggagagct cgtactcgcg
    12121 cgggttcagc tcgtagtcga cgaaggtgtg cggcagttcg gcctcgccga cgtgaccggc
    12181 cgacatggcg atctcggcct cgccgtactt gttctgccgt ttgcgggtgg tggagctgaa
    12241 ccgctcgatg tgggtccgca ggctcggcgc cgagtcgtgt acggcggcga agtcggcccg
    12301 ggagagggtg aggagggtgc cggaggtctg ggcggtggcc gtgtaggcgt ggcgggagtc
    12361 gccgtccagg agggcttcct cgccgaagtg ctcgccgtcc gcgaggaccg cgagggcgac
    12421 ttccgcgccg tactggccgt ggccggtctg gctgacccgg ccgtgggcga tcatatggat
    12481 gcggtcggcg ggcgtgccgc gttcgacgag gacctcgccg gcggcgaagt cgcgctgggt
    12541 gcagcggtcg gcgagggcgg tgagggcgtc gaggtcctcg aagccccgca gcagggccag
    12601 ttcaccgagt tcgcggggga tcacccggac cgcggcaccc tcttggacga actcgatgcg
    12661 tccgtcgccc agggtgtggc gcagccgccg gttgacccgg taggcgccgc ccttggtctc
    12721 gacccagggg agcatccgca gcaaccagcg ggaggtgatc tcctgcatct gcggggcgga
    12781 cttggtggtg gtggcgaggt tgcgggcggc ggcggtgctc agggactgct gcggtgcggc
    12841 cgatacggtc cggggctccg ggctgctgtc gacggtcatc ggggtgggcc tctccttgcg
    12901 tgacagggcg gtcgacgcgc acgggggcgc cgaccgcgaa agggaggaat ggggaaaggg
    12961 aggatctcgg ggacccgccc acgcagagga ccgtaatggc cggtcaggcc gtgtcttcgg
    13021 aatgctgacg cgcttacttc gaagcggtga taaaaaattg aacacggttt atcgggccga
    13081 tggatggcat tacgccaccg tcgcggaggc cggggcggga cgcggcgggc cgcacaagac
    13141 gatcaccgcg tcgcgcccgt acatgatcaa gccaaggcgc gtcgtggacc ggtcgcccgt
    13201 gttcgatttc atgccgaagg ccgggccggg atcctcaggt gaggaccagc cagcggcggc
    13261 cgtcgaggag ttcacgggcc gcgtcgaggt ggccggctgg cacgcggtct cggtgatgac
    13321 gtgcagcagg acgtcgcgca gggtgtgcag gtgtggttcg ccgaagagat cgcggggcca
    13381 ccaggcaggc ggggcgtcgg tgggggtggt ggtgatgacg gcgtcggcgc gttccgcccc
    13441 ccgccggtac cgttcgagca catcggcggc cggcgtgtcc ggggccaccc gccatgccgc
    13501 gtcgccgctc gtcaggcccc ggacgaccgt ctcgtccccg gcgacgaccg cgcggaacca
    13561 gaaccgctcc acgtccagcg tgaggtgctg gaccatcccg aggcagtgcc agccggacgg
    13621 cagcacgggg cgtcgcaggt ccttcgggtc gagcccgtcg aggatgccga ggacgtggcg
    13681 ccgctggccg tccaggaccc tgagaagagt cccgacctca ccgctcggaa tcgattcgct
    13741 cacatgtccg ttcatggtcg gacagggttc ctgaatggcc tcgcccgtgt ggggggttcg
    13801 cagatattcg ggcggctcgg tcggcctcgg ggcggtggta cccggggatc actgggtggg
    13861 gccgtcgtcg tcgccggtgc gcggcgggtt tcgggatttt ggcggtggtc cgtcatactc
    13921 ccgggggctc acaccggccg ggggcgcgag gtggtcgttc tctcccgggg tggcgaatgg
    13981 aggaggaacg tgcagcacca catacgccgg acggcgctcg tcgcggtggt cctggtcgtc
    14041 gcggccgtgc tcgggggctg ttccggccag ccgcggaagg tgtcgggact gctggacacc
    14101 acccggcggg tgccggcgac gagcaggctc gcgacccggc cgcacctggt caggcaatgc
    14161 cactccggat ccaagcaggt gcggcacacg tccgggcgcg gcagcaagaa gcgcacctgg
    14221 tacacgacca ggtcgacgac cgtgtgcacc aaggtgcggc ggggcagcgc acctggtaca
    14281 cgaccaggtc gacgaccgtg tgcaccaagg tgcggcgggg caccgagacc taccgccggg
    14341 tgatccacca ggagcgctgg tgcgtcatgc tggacgatgt gggcggcaag cgctcccggg
    14401 accgtgtctg gtaccaggtc agcaggaaca cctatacgga cacccaggtg cgcaggtccg
    14461 gcagcaaggt gacgatcgag ccggagcggg acggctgctg agtgacgcgg gcgggcgcgc
    14521 ggccgggcgc gccgggccga cgcgcggccg ggacgacgcg cggccgggcc cgccgggcag
    14581 aagtcccgac gagcccttcc cccggtgagc ccttcgcacg acgagccttt cgcccgccga
    14641 actctccgcc cgatgaactc ttcgcccggt gagccccgcc gcgcggccgc ccggccgagg
    14701 tcagcgcagc cacgcgtggt cgcggacgac cggcagtccg gcccaccagc ggcccaggcc
    14761 ccatgtggtg cccgcgccga cggccgccac ggcgatcagc gccaccgcgt agatcaggtg
    14821 gtagtcggcg aacggattcg tcgacatgct cggcgagccg tcggccagat gcctggcggg
    14881 cggccattcg gcggcccaca tcagggccat catggcggtg cccgcgaccg cggccggccg
    14941 tagtgccacg ccggccgtca cggccgcgcc gatgccgagc atgcccagca tgaacagcca
    15001 gtcggcccag ccggcaccgg cccacgcgtg aaacgtggac cgcagggggc ccacggcgac
    15061 ggagccgagg aaccccttcg tcggggacac cccgtcgatc catgccttgc cggacgccgt
    15121 ggcgtacccg aggccgaacg tcttgtcgag gaacgcccac aggaagacga acccggtcag
    15181 gatgcgcagg gacgcgagag cgcgcgcctg cctggtgtgc gtgtcgatgc ctgccgacac
    15241 ggcgagcgcg gttccggtgc ggtcgttccg gaacgacaga cgcaagcccg ggtggcggtg
    15301 ggagtgctcg tgcacggcca tgatggtggt cccctctggc atgcccaggt cctgttttcg
    15361 ttgacggctc cactttcccg gtggacaccg cccggcgccg gaggccgaag ggctccggcg
    15421 gtagggccca acgtccctgt gcgcgggcgc ggttggcgcg ccgcggcccg gggcagggat
    15481 cggcggatcg acgaggacgg cgccgggacc cgttccggtg tccggcggcc cacaggagtt
    15541 tgggacactc tttgcgcggg acacgcaact gaggtccgcc ttctccttgt ctgccaggga
    15601 gtcgggcccg tcagggccga aggtacgaga gagcggggta gtcagtggga cggcgcaagg
    15661 gcagcatagg gatcgcactg gtcacgggtg ccgtgctgat gggtgcgagc gcctgtggcg
    15721 gcggcagtgg caatggctcc aacacggtcg gcggtgacgc gaaggcgccg ggcaagtcgg
    15781 cgccgagcgc ctccgcttcg ccgacgaagc ccgcgggccc gccgatgctg ctggacacga
    15841 tcaccccgca gagcggcacc acggtgggcg tggccatgcc gatctcggtg gtcttcaccg
    15901 accccgtggc ggccaaggca cgggccacgg tggagaagca catgaaggtc agcacctcca
    15961 cgccggtggc gggcgcctgg cactggttcg gcgacaagcg cgccgactgg cggccgaaga
    16021 ccttctggcc ctccggcacg aaggtgaaga tcgacgccga catggagggc gtcagcaacg
    16081 gcgccggacg ctacggcgtg cacgactaca cgcacacctt cacgatcggc gacgacgtcc
    16141 gcgcggacgt ctcggtcacc ggccacacca tgaaggtgac ccgcgacggc aagctggtgc
    16201 gcaccctgtc catcaacgcg ggcagccccc agtacccgac gtggaacggc atcatggccg
    16261 tgatcgacaa gcaggagaag gtccatatga cctcgtgcag cgtcggtatc agctgcgaca
    16321 agggcagccc caactactac gacctcacgc tgccctggga cgtgcacctg acccagagcg
    16381 gtacgtacgt ccactactcg accggcgacc ccaccccggg cggcggcagc gcgcggggct
    16441 cgcacggctg cgtgcacctg tccctgtcgg acgccaagtg gttctacggc caggtcaagc
    16501 agggcgaccc ggtcaccatc accggctcgt cccgtgccaa ggcggatccc gacaacggct
    16561 acgcggactt caacctggac tggacccagt ggctcgcggg cagcgcctcc ggggagggca
    16621 cgacctcggc gctgtgatcc acccgctcgg tgtcccggac ggccctcgcc acggcaacgc
    16681 ggcgagggcc gtgccgcgcg tacggcggct ctgagacgtc ggatcgggta cgccccctgc
    16741 ggtccccggc gtcgcgaccg gccaccgcgc ccccgaccac cgcgccccgg accaccgagg
    16801 ccccggacca ccgaggcccc gatcaccgtg gccccaggga ccggttcctc tcctgccggg
    16861 ccgcccacgc ggtcagcgtc cggtagcaga ccttgccggt ggggccgagc ggcatctcgt
    16921 ccaccagcag caggagttcg gggtgtttgc ggcggcccag gccccgggac agcaggtgtt
    16981 cggtgagatc ggccggcgtg ggcgcggggg tgccgggggc cgggcggaca caggcgcaca
    17041 ggcgttcccc gaggtcgggg tcgggcaccg ggacgcacac cgcctcggcg acggacggat
    17101 ggccgcccag ttcgtgttcc acctcggcga ggctgatgtt gaggccgccg cgtacgacga
    17161 tgcgcttgag ccggcccagg acgtgcagcc tgccgtgctc gtccaagcgg cccaggtcgc
    17221 cggtgcgcac ccagccgtcg ggggtgcggt aacgggcgtt cagctcgggc gagttgacgt
    17281 agcacagggg tgtcatcggg cccagtgcct cgatctggcc gctttgtccg gtgggcagcg
    17341 ggcccccgtc ggggccggtg atccggatgc gggccacctt ggggtcgggg gtgccgacgc
    17401 tgtcgccggt gggccggctc tcccccgccg tatggcagtt gacgccgtcc gaggagccgt
    17461 agacggtcac caccgggcgg ccgaagcggc ggcggcacgc ctcggcgaca gccggtggca
    17521 gggcggcgcc gctggagacg acggcgcgca acgacgaggt gtcctcgccc ggtcgggccg
    17581 ggaggtcggc gatgcggcgc agcatggtgg gcaccgcgaa cagatgggtg ggacggtgct
    17641 cggcgatcag ccggagcgcg cccgccgggt cgaaccgcga gggcacgatc agggtgccgc
    17701 cgaggacggc gagggtgacc ggcgtgccga gggaaccgaa ggaggaggcc agcggcacga
    17761 ggacgaggtg gcgggccggc accgcggggt ccgggtgcag ggcgcggaca tagcgggccc
    17821 ggccgccggc gagggcgtga tggctgtagg cgaccatctt gggttcggtc tcggagccgg
    17881 aggacaccag gatgcgggcg ggcccgtagg ggtcgacggg ccccggccgc cagggttcgg
    17941 gggctcgggg cctgggcggg tgcaggccga gtgcgccggt gcggtccggg ccggggacgt
    18001 accgggtgac caggtgggga aggtccgtga gagcccggat ctgctcggcg gaggcgagca
    18061 cggcggcgcg ggcccgggag cgggccagca gggcgcgggt gtcgcggtcg tcgccgctcg
    18121 ggggcagggg cagggcgacc gcgccgagcg cgtacacggc gagttcggcg gccacggcgt
    18181 cgcgtccgtc gggcagccgt agcgccacca cgtccccggc ggcgaggccc gatccggcga
    18241 acagggcggc gacacggcgg acttcggcgc ccagggccgc gtaggtcagc gtcccggcgt
    18301 cgtccaccag ggcggcgcgg tcggggtgtg cgcggacccg ggcggtgaac agcgtgtaca
    18361 ggtcggcgtc cgggcacagg ccctcggaca cccaggccag gcggcgggcc cggggcacga
    18421 ggtcggggaa gggcacaccg gcgcgtgagg tccacgccag gtgtccgccc cgggccgcgg
    18481 ggagggtggc gggggcgacg gtcatgcgaa ctcccaggga gcgtgcggtc gggcgtggcc
    18541 gatgagcggg tccggtgggg cgacggccgc cttgaaggcg gggtcgtcgg ccagggcggc
    18601 caggtcggtg tggacggggg tggcggtcag gcccgcttcg gccaggcggt gcgtccactc
    18661 gtcggtggtg agggccgact cctcggcgcg gcccagcagc cggtgcaccg cctcgggatt
    18721 tgcgcgggcc tttgggccga ggtacagatg accgtccgcg gtgcgcacgg ggcggtccgg
    18781 tgccgtccag cgcacccggt gcgcggggcg cgggatcagg gcggcggcgg agaccaggct
    18841 ggagtcgacg cggccgcccc gcccggtccg tgcccggtgc gccagcgcgg ccagcacgcc
    18901 ctgggcgcac accagcccgc cgaggacgtc ggtgagggtc atcagggagg gggccggggg
    18961 ttcgtcggcc gggcgtacgg cggcggcgag tccgctgtgc acctgggcga ggtagtcggt
    19021 gccgaggggt ggccggtcgc cgagggtgtc gccgaagccg gaggcccagg cgtacaccag
    19081 ggcggggcgg tcggacagca ggtcggcggc gtccaggccg agccgggcgg ccttgccggg
    19141 ggcccagttg tgcacgaagg cgtcggcctc ggcggccagc gcgcgtaccg tctcccggcc
    19201 ccgcgcggtc gtcaggtccg cctcgacgac ccgcttgccc gcgttgaggg cggtgaaccg
    19261 ggccgaggtg tccctggcca gcgggggcag ccagcgcatc gggtcgccgc ccgggggctc
    19321 gatccggatc acctcggcgc ccagcatccc gaggacgtgt ccggcgaggg ggccctgcac
    19381 ccggcgcgtg gactccacca cccgcaggcc cgcgagcggt aggggcgggg cgcccccgga
    19441 gcgcggcgcg ggcatatcgg gagccgggtg cgcgggtccg gacgtccgcc gccggggaac
    19501 cggggtgacg gccggggcgg gcagccggtg ttcagggtgg acggccgggg cgggggtgag
    19561 ccgccagggt tcggggtgga cggccgggtc ggggtcggca ccgagggtga ggaggctgac
    19621 gccggtgtcg tacgcggcgg cccgcaggtc cggcagggta cggcggcggg cggcggcgcg
    19681 cagttcctcg ggcaacgggc acacggcggt ggcgaaccgc tgctggaagg gcagccagcc
    19741 gcgccccgcg agggcggagg gtacgccgag ccgggcccag aactcccgcc aggccgacgg
    19801 gtcgagggtc tccagctcca cgtgggcgcc gtcggccgtc tccagggtcg cgagaccgcc
    19861 cgcgcacggc tccggtcccg ccgtggcggg cgggccgtcc gcttcgcggg ccgtcgcggc
    19921 ggcgaggtac tggccgaccg ccagcaacgc cccttgcgcg accgaggtcc gcacctcgcg
    19981 caggtccagc ccgcgggccc gcccgatccc ggcggcggtg gccccttggg cggcgaggac
    20041 cccggccacc accgaggcgt agtcgacggc gagcggggcc gggccgccgg tggcccggcc
    20101 gtggatgtgc atgagcccgc aggcggcctg tacggcacgc tcgtccggca gttccatgcc
    20161 gaccggaccg gcccagtcga gcgtggggcg cacctgcggc acacccggtg cggtgtgccg
    20221 gagtaaccgg tcggcgacgg cgccggcgac caccggacgt acgacggtac gaggactcac
    20281 ccgccctccc cgccgggccg gcggccctgc accgagtaga agacgctgga ggcggcgcgg
    20341 aagccggggt cgcgcatcaa ctgccgtacc cggtccagct cttcgtcggt catgccctgc
    20401 tccaccagcc ggtcgcggag gttgcgggtg tggttcgact ggagtcccag gccggggtcc
    20461 tgggcgtggc ggacgccgat gtgcagatgg acgtcgatac cggtcagtcc cgccgcgcgc
    20521 agggccccgg gcacggcgcg tccccagtgc gggtcgccgc ccgcggcccg catcgcggcc
    20581 gacttggccc gcaggaagcg gaggtacagt tcctcggccg ccgcgtccgg ggtcagcagc
    20641 gggggctcgt aggaggcgtc gatctcgtcg atctggagca gtccgccggg ccgcagggcg
    20701 cgtacgagcc ggggcaggac ggcggcgcgg gtgggtacgt gctggagcac caggcgcgcc
    20761 acgatcaggt cgtaggccgc ctcgggcagc gggtcgcggg ccacgtcgag ggcggcgacc
    20821 ttcagctgcg ggccggggac gaggtcgcgg gggtcgcggt cggtggcgag gaccgagccg
    20881 cccggtgcga cccgccgcgc cagccagcgg gcgatgctgc cgccgcccgc gccgatctcc
    20941 aggcagtgcc agcccgggcc gaccccggcg gcggccagcc ggggcagggt caccgggtcg
    21001 taggcggcct ccagacagcg gtgctggtcg cggctgtgcg cggtgccgtt gccgaagacc
    21061 acgcgggccg gggccggcgg tgccatgcgg gggttccttt catcgagggg gtcggccggt
    21121 cacaacgcgg ccgtggggag ggtgagttga cgcaggaggc tgaaggtgcc gtccgtcagg
    21181 tccagcggcc ggtgcccgcg agcccggtgc cggtgaggcg gtgcgccagg gcggcgcggc
    21241 ggaccttgcc ggtgccggtg cggggcacat cgtcccaggt gaggacggcc ggt
//
