LOCUS       NZ_CP094483            33797 bp    DNA     linear   CON 27-MAR-2024
DEFINITION  Streptomyces murinus strain JS029 chromosome.
ACCESSION   NZ_CP094483
VERSION     NZ_CP094483.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces murinus
  ORGANISM  Streptomyces murinus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Draft genome sequence of Streptomyces sp. JS029
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8303622)
  AUTHORS   Chi,W.-J., Kim,K.-T., Park,S.-Y. and Kim,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-MAR-2022) Agricultural Life Science, Sunchon National
            University, Jungangro 255, Suncheon, Jeonnam 57922, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-MAR-2021
            Assembly Method                   :: Unicycler v. 0.3.1
            Assembly Name                     :: JS029
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 164.82x
            Sequencing Technology             :: PacBio; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028753175.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 03:30:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,582
            CDSs (total)                      :: 7,481
            Genes (coding)                    :: 7,273
            CDSs (with protein)               :: 7,273
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 215
            CDSs (without protein)            :: 208
            Pseudo Genes (ambiguous residues) :: 0 of 215
            Pseudo Genes (frameshifted)       :: 110 of 215
            Pseudo Genes (incomplete)         :: 125 of 215
            Pseudo Genes (internal stop)      :: 20 of 215
            Pseudo Genes (multiple problems)  :: 41 of 215
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:08:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 33797
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP094483.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from National Institute of
            Biological Resources.
FEATURES             Location/Qualifiers
     region          1..33797
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="other"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(Neocarzinostat or bcpB or frbD or mitE or prnB or
                     CaiA or bacilysin or orf2_PTase)"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..33797
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Neocarzinostat or bcpB or frbD or mitE
                     or prnB or CaiA or bacilysin or orf2_PTase)"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="neighbouring"
                     /product="other"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..33797
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[12423:13797](+)"
                     /cutoff="20000"
                     /detection_rule="(Neocarzinostat or bcpB or frbD or mitE or
                     prnB or CaiA or bacilysin or orf2_PTase)"
                     /neighbourhood="20000"
                     /product="other"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      12424..13797
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Neocarzinostat or bcpB or frbD or mitE or
                     prnB or CaiA or bacilysin or orf2_PTase)"
                     /neighbourhood="20000"
                     /product="other"
                     /protocluster_number="1"
     cand_cluster    1..20069
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..20069
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7507:10069](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(7508..10069)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="2"
     gene            complement(32..583)
                     /locus_tag="ME763_RS00005"
                     /old_locus_tag="ME763_00005"
     CDS             complement(32..583)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS00005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ME763_00005"
                     /product="hypothetical protein"
                     /protein_id="WP_274505971.1"
                     /transl_table=11
                     /translation="MTTTPIKAGAVDRILSSCLGSEAGRFHPVIAVRTPAASKDWDGTV
                     IAVDSAGQYVQCQTKGERGSSPDVPPTFINDRLWGTGHIVEYFDAVGQSAGKGRYLSLG
                     AGHYTTAVAKITVSYGEDPKQYPAVMAGGAFFYTASFSTGSSPAKLIAAMSTSYVHAYN
                     AAGKEIYNQKKDPQFTGTSE"
     misc_feature    complement(564..577)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            576..848
                     /locus_tag="ME763_RS00010"
                     /old_locus_tag="ME763_00010"
     CDS             576..848
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS00010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ME763_00010"
                     /product="hypothetical protein"
                     /protein_id="WP_274505972.1"
                     /transl_table=11
                     /translation="MVTLVTVTAGGAEAEGAEDGVVPVPAFEEPRLGPGDAAALVGLPP
                     LPAWAGSAALSPPKTLTAPTLNAATPAAILNGSPHLRTSEVCSSS"
     gene            complement(937..1584)
                     /locus_tag="ME763_RS00015"
                     /old_locus_tag="ME763_00015"
     CDS             complement(937..1584)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973087.1"
                     /locus_tag="ME763_RS00015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00015"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_085568343.1"
                     /transl_table=11
                     /translation="MEVNDVGPAAAVGGVSDRELWARAVNGDRDAFGRIFDRHAKTVYN
                     HLFRRTADWAEAEDLTSAVFLHAWRRRSEVALDRDSALPWLLGIAERLLSNTRRRLRRA
                     EALLRRLVSHDESVGDHADRVAGEVDDARRMSQLHRALARLPRHEREVVELCMWSGLDQ
                     QAAATALGVAVGTVKSRLHRARRRLGADLAGRPGVATSSTSKNPVTVEEVAR"
     gene            1915..3810
                     /locus_tag="ME763_RS00020"
                     /old_locus_tag="ME763_00020"
     CDS             1915..3810
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006139915.1"
                     /locus_tag="ME763_RS00020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00020"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_274505973.1"
                     /transl_table=11
                     /translation="MHERKPHRRLSRILAAGVLAAAGVAAASPAAQAVGHRTAADSRQH
                     AFEQAAADYDVPLPVLLAVAYHESAWDAHAGERSTGGGYGPMHLTDVTTGMLAAGDAGA
                     VGRADLPELASAPSLHTLQAAARLTGLPGKRLRADDAANIRGGAALLASYEKSAVGSTP
                     KDSGKWYAAIARYSGSSGQRAARAFADRVFATIESGAQETTRDGQHIELPASPSVQPAV
                     KQLSVLHLRATAATGDTECPATIDCAFLPASAANGQVSDRPANGIRIDSIVIHDTESSY
                     DAALNTFQKPGGGSAHYVIRSSDGAVTQMVPTKDISFQAGNYSTNLHSIGIEHEGYAAA
                     GGTWYTQTEYETSAELVRYLAERFGIPLDRQHIIGHDNVPGPSSALVSGMHWDPGPSWD
                     WERFMRLLHAPVGGRHGVGRVGSVVTITPGFARNQQTVRVCPSDDPTGATPECTERTQP
                     SDFVYLRTAPSATAPLFGDQAIHPDGVGSDSINDWGSTAAAGQQFVVADRQGDWTAIWY
                     SGTKVWFLNPHGCNTTPARDVTVVGAAGTSPVAVYGSSYPDANEYPAGLSPSTQAPLSF
                     YTIPVGQAYVTTAAPAPTDDYFPSTGRVVTGGKSMYTIQYNHRTALVYASDVSAR"
     gene            complement(4975..5550)
                     /locus_tag="ME763_RS00030"
                     /old_locus_tag="ME763_00030"
     CDS             complement(4975..5550)
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018565816.1"
                     /locus_tag="ME763_RS00030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00030"
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="WP_172427734.1"
                     /transl_table=11
                     /translation="MNRAVVITEALGLLDEVGLDAVSTRRLAKRLNVEQPSLYWYFRTK
                     KDLLAAMAEAAMEPHTTAPLPSPGDDWHDWFADNTRSFRRTLLTRRDGARLHAGSTPTG
                     DLARLRRKMEFLVASGVPEHDAQMAMLAAGRFTVGSVLEEQADPGPGDDADLPADMPVI
                     DHESAFEAGLALILNGLVHRTGMRGTGM"
     misc_feature    complement(5550..5570)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
     gene            5628..6878
                     /locus_tag="ME763_RS00035"
                     /old_locus_tag="ME763_00035"
     CDS             5628..6878
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018565817.1"
                     /locus_tag="ME763_RS00035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00035"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_085568340.1"
                     /transl_table=11
                     /translation="MAEGWGERPLRVLVAGGGIAGQALAFWLSRGGHRVTVVERFPALR
                     AAGAQVDLRGQGIEAVERMGLLDAVRSKLVDEAGVAFVDACGRARATVMANTSGRGRQT
                     LTSEYEIMRGDLVRILHDATRDDAEYVFGKSVDGFEQEEDKVVAHFSDGSCGEYDLLVG
                     ADGQGSRIRRAILPEGFDPYRRLGIHMAYWFVPRIASDSNIRDTYMVPGGRQIMRRSHN
                     PTETQVYFVLREGSEGASAIHRAPVERQQEFWASRFHDAGWQTERFIEGMRTSPFFYSQ
                     EIVQVRADAWSKGRVVLAGDAAHCASPYSGMGISGGLVGAHVLAGEINRHPGDLPTALA
                     NYESALRPFVNKIQGQVNPRLLRLAMPMTRRAIDAFQATTALACRLHIPDLAARLSKED
                     RGGTWRLPENPAPTTTL"
     gene            complement(7508..10069)
                     /gene="lanL"
                     /locus_tag="ME763_RS00040"
                     /old_locus_tag="ME763_00040"
     CDS             complement(7508..10069)
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019981073.1"
                     /locus_tag="ME763_RS00040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00040"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_085568339.1"
                     /sec_met_domain="Pkinase (E-value: 1e-19, bitscore: 69.6,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 7.8e-16, bitscore:
                     56.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVSIAGRGGWSDETWSYLNDPRMPAMEHGWKLHVSARPADLDTV
                     TVLVLPVLSRHVCHAKFARDPDVLRRLNSGAVSAGAVGKAITVYAPADTVAEIARELAA
                     VLRDREGPRVVSDRRVDPRAPVYYRYGPFTGDYRTGRSGRLESVMTGPDGRMFDGLAVG
                     RYRCPPWAQDPFASGSRPGDEPSAPHFGGGRYTVTAGITRSPQGNVYRAVDRVLGQPVV
                     VKQARAFVGEDESGADARHRLRNERAVLTALHGVTGVPRALDYFAHRSDEYLVMSACGD
                     RDLRREVLRDGPYRDDGTRPERALSALASRLLRILDAIHGRNVVVRDLKPDNVVLDASR
                     PGHCHVIDFGISERDGAGPGGATPGYGAPVLRTAGPAAPADDYYALGATLFFAATGMDP
                     VIVDSDHTVNRDRTLACLAWALPGPAHREIRSRISGLLSFHPAERTATADRLRTGTAGT
                     AGTTRRPVRPRIDDDLLDEIIEHTTAFCVDEASAIVDPERAARLNVPTSIDVYGGSSGL
                     GLELLHHLHRPRVRSTVTALTRWTAEQSRNLPPGFYTGRTGVELFLTQAQLTAGAAGTY
                     EDPLPGQPALPGRAPDGGPPEADLIAGAAGIGLGRLLLARLALRSGHRHSAHRHLAVAA
                     DCDRMLASGTARLTPGGTDTAGRAALREGIAHGEAGVACFLLEYGGVTGDMDAISRSEQ
                     AGAHLAAVTPDIIAAATGPGATRRYGSWCRGLAGIGTVLVRAADRLDEPGHLDLAQRSA
                     RACAALAPRMPLVTQCCGLAGVGELMVDVAEASGSEEFWETAETIALLILGRSGGTWSR
                     PVFPDTGLTGPSATWADGSAGVLAFFRRLRARGGPRLGRVV"
     gene            complement(10072..10254)
                     /locus_tag="ME763_RS00045"
                     /old_locus_tag="ME763_00045"
     CDS             complement(10072..10254)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192895.1"
                     /locus_tag="ME763_RS00045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00045"
                     /product="SflA family class IV lanthipeptide"
                     /protein_id="WP_085568338.1"
                     /transl_table=11
                     /translation="MPVAVPDLLQAGGFRDAGPLEIDDEAIVFEDDDRDDREPTACLAD
                     PWVTATTRFSCDLNS"
     misc_feature    10602..10616
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            complement(11084..12124)
                     /locus_tag="ME763_RS00050"
                     /old_locus_tag="ME763_00050"
     CDS             complement(11084..12124)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004949668.1"
                     /locus_tag="ME763_RS00050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00050"
                     /product="PAS domain-containing protein"
                     /protein_id="WP_274505974.1"
                     /transl_table=11
                     /translation="MDETERKAPSGEPAGPPGRNPFGALAELTPAAAFMRDGAGRYVWA
                     NHAYAHLYGTTRDAVIGRHLSDLDEPANAGRFLAMDQQVLTDGKSIRHALTYRRPDGTP
                     AHAAGYRFPVRWGAERCVAGIYVDVTDYVRAMDQRHRAEADLRALRDHSGLACVRLAPD
                     GRVSEAGTATAEILRVRLSDLTGLRAASLLADTPERGALLRLWDDLIAGRRRSARASAV
                     LVDGEGWQRRARIRLTTVGATAPGVTGVWAVVTHLGRRQQTQPTLTAAQIRIVALLAAG
                     RSNADIAEELRLSRQTLDYHLSRLRVLLEAPTRPAMVARAYVLGLLSPRAWPPRSPTAA
                     HPSSPV"
     misc_feature    complement(11687..11689)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12248..12265)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.09"
                     /tool="antismash"
     misc_feature    complement(12271..12288)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.94"
                     /tool="antismash"
     gene            12424..13797
                     /locus_tag="ME763_RS00055"
                     /old_locus_tag="ME763_00055"
     CDS             12424..13797
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) other:
                     bacilysin"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607917.1"
                     /locus_tag="ME763_RS00055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00055"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_085568336.1"
                     /sec_met_domain="bacilysin (E-value: 1.1e-55, bitscore:
                     187.9, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQVLYVHAKGGPPVGHALTRVAGRATVHLLALSGLPVGVAEDAA
                     RLCASVMTPSRAEHADLVELITTRAREVGADAVLTFSEYAVVAVAEACRRLGLRGAGAA
                     AALARDKRLMRATWDRHGVPQPRFRPVAGLAELERATIELSCPLLLKAAWSAGSTAHQI
                     IDGPGQARHAWHRSRQVMAESAQLGFAEMHVRGASEDFIVEEIVTGRAEEWFDGPGWGD
                     YVSVEGVVVDGDFRPVCLSGRMPTVWPFTERAGITPAAVDSGAQRRIVELARQAVDALG
                     LENCGTHTEIKLGADGRMWVIETAARFGGAMTVPQIEDVFGLDLVGMFTDQLLGRSPGW
                     PARTLTPADAEGATGSLVVLAVDGEGTPWPRRHLWDSSTVVRKAPIGAGSTLSVVRESS
                     LPDGSPVPVYDPAGGANTMAGLCLLSADRPQSVVRDFTALVAALPDILPVDAAEEARA"
     misc_feature    12865..12867
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    12868..12870
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13794..15806
                     /locus_tag="ME763_RS00060"
                     /old_locus_tag="ME763_00060"
     CDS             13794..15806
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PPDK_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004949661.1"
                     /locus_tag="ME763_RS00060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00060"
                     /product="PEP/pyruvate-binding domain-containing protein"
                     /protein_id="WP_085568335.1"
                     /sec_met_domain="PPDK_N (E-value: 2.2e-35, bitscore: 121.2,
                     seeds: 105, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFAPDEARAADAAGDRTVVGGNLSLPLFRTLSGVLAGHPYLKVV
                     VDRAEDTWHLLDTRVHPFHVDYIATRVLGMTPRQLDAELDAFNAQVYMAPDRRFLLGIL
                     SLHSDEDAEGAERPFLVLETTEADTMHGALLQEFYDYVRHRVDGRLPLLLKPANHGQEH
                     ELALVGDTRIPRILSQELFGSRTRTCLNPGVAEGRLRYFRSPQEYRAGVAGLGWADIVA
                     MAGLPDDVPRVAGFINTRPTTPLSHTNVLASGWGIPNAIVRDLDALVERHGLDGAWVRY
                     RVREDAVTLEPLSCAPALERPVWDTQRIHIGAPLIGDAPIMELHRLRLADRDSYGTKAA
                     HLGELHHVLDSRTADLTAFYARPRPPRPDLLAHLGTRLGEPEAPLERLRLTAAERVAQT
                     VRAPRGVALPFHLHHLYLTSSPALQQGIGKLKLALELDALDMIDPLSLDLQHLMRSTPM
                     PEEVARAITGAVPRLVADGRRLVVRSSSNAEDLPGFSAAGIYDSVTTVRGTEQLMDAVI
                     HVWASLLSPRSVRMRHQVGISLDDTYMGVIVQEYTPADLGGVLVTCNPTRREDFRNVYL
                     NCTAGSPERVVDGTVLPHQYLYNTVEGGGRTVAVGSSGTDLPADTRQSLAELALAGRLL
                     QSHFSTDDPDDALDIEWLMTGEGAFQLVQVRPYAR"
     gene            15803..17176
                     /locus_tag="ME763_RS00065"
                     /old_locus_tag="ME763_00065"
     CDS             15803..17176
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607919.1"
                     /locus_tag="ME763_RS00065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00065"
                     /product="MFS transporter"
                     /protein_id="WP_085568334.1"
                     /transl_table=11
                     /translation="MRRHGPAPWRRAPHEDLTPAARRVIRLNNGFQLLFNLLWWMPVFY
                     AYQRDAGLSDGQIFGIQSIYYIAFCLFEIPTGLVADRIGARNCLWAGAVVMTAANLVPV
                     FSPSYPGFLLHFLAIAAGRSLTSGAASACLYDGLRAEGADAHYLRAEGTARALGLAAKV
                     VCWPLVGPLMVLAPQAPYVLSAASAAGSLGCALALPRPAPRKASGASRASGRREAALLR
                     DTGAALRALRSSPWLALLMVQGVAVFTLSRICQVNLFQPVLLHHGIGEGSTGSVLAAMT
                     VAEAVASARPQWLGSRLSPTAWVSLLSVALAATLAGTTVGGPWTVAALLCVFAAITGFC
                     YPVQRKLINDAIPKTAPRATLLSVESIVDRGVCALAAVAAGACLAAGRLDALLWQSAAV
                     TCALIPALHLALRRVNRAARTRGAGTATGADAGSGRARTLPADEPVALPVDEGAAPRA"
     misc_feature    17340..17357
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.83"
                     /tool="antismash"
     gene            17551..19194
                     /locus_tag="ME763_RS00070"
                     /old_locus_tag="ME763_00070"
     CDS             17551..19194
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568563.1"
                     /locus_tag="ME763_RS00070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00070"
                     /product="M4 family metallopeptidase"
                     /protein_id="WP_085568333.1"
                     /transl_table=11
                     /translation="MTHGNIRRQRTTLAVATAVAATAALLSTSLTASAAARPTADSARP
                     AGAPVALSAAAHTGLIRSAQAELAGTAKALGLGSQEKLVVKDVVKDGNGTVHTRYERTY
                     AGLPVLGGDLIVHTSKSGRTQGVTRASKATLKLASLTPRIAAATAQKQALSLAQKDRSA
                     KPAVDRAPRKVVWAAGGTPVLAYETVIGGFQDDGTPNQLHVITDAATGKKLFQYQGIET
                     GVGNTQYSGKVDLTTAQSGSSYTLTDDSRGGHKTYNLDHQQDSTGTLYSQDNDTWGDGT
                     TSNAATAAADAAYGAQETWDFYKNTFERNGIKNDGVGAYSRVHYGDSYVNAFWDDSCFC
                     MTYGDGEGNNDPLTALDVAGHEMSHGVTSNTAGLEYSGESGGLNEATSDIFGTGVEFYA
                     NNSSDPGDYLIGEKIDINGDGTPLRYMDKPSKDGGSADYWSSSVGDEDVHYSSGVANHF
                     FYLLSEGSGAKTINGVDYDSPTKDGSTVTGIGRDKALQIWYKALTTYFTSTTDYADARK
                     GTLSAATDLYGADSAEHKAVEAAWTGVDVH"
     gene            complement(19774..20367)
                     /locus_tag="ME763_RS00075"
                     /old_locus_tag="ME763_00075"
     CDS             complement(19774..20367)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007261956.1"
                     /locus_tag="ME763_RS00075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00075"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_085568332.1"
                     /transl_table=11
                     /translation="MAEGSYHHGNLRAALLERAEEVLAESGAVGLSLRGLARDLGVSHA
                     APTRHFRDRQAVLDALVTDGFTDLNRRMEAAAGGPGPVEGRLAALGRAYVGFATERPAL
                     LELMFTAKHEVEPDAEIRVLGHRSLEIAAEVIAEAQRTGAVRSGDAVRLAQVAFSTVHG
                     LAVLAVGDLLDDTPVGEATDLALEILLTGLRGTP"
     misc_feature    20383..20399
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 21.07"
                     /tool="antismash"
     gene            20469..21260
                     /locus_tag="ME763_RS00080"
                     /old_locus_tag="ME763_00080"
     CDS             20469..21260
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (9-186). E-value: 3.9e-11. Score:
                     35.1. Matches aSDomain:
                     nrpspksdomains_ME763_RS00080_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007261957.1"
                     /locus_tag="ME763_RS00080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00080"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_197697421.1"
                     /sec_met_domain="adh_short (E-value: 5.6e-34, bitscore:
                     116.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTMSYQGTTAVITGASSGLGEEFARQWAERGADVVLVARRLDRL
                     ETLAAELEKWHSVSATPIAMDLAEPGAGVALREELAARGRSVQTLINNAGFGSHGAFAE
                     QDPEQIARMIRLNVGAVTELTRAFLPQLAADGRGALVNVASTAAYQPTPAMAVYGATKA
                     FVLSLTEALAHESRDSALRVLAVSPGPVATEFFDVVGSRKAIVGRMATAADVVAATRSA
                     LEGRRTPSSVIAGLGNRISATAARLAPRRIALAAAGRALGA"
     aSDomain        20496..21026
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ME763_RS00080_PKS_KR.1"
                     /evalue="3.90E-11"
                     /label="ME763_RS00080_PKS_KR.1"
                     /locus_tag="ME763_RS00080"
                     /protein_end="186"
                     /protein_start="9"
                     /score="35.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TAVITGASSGLGEEFARQWAERGADVVLVARRLDRLETLAAELEK
                     WHSVSATPIAMDLAEPGAGVALREELAARGRSVQTLINNAGFGSHGAFAEQDPEQIARM
                     IRLNVGAVTELTRAFLPQLAADGRGALVNVASTAAYQPTPAMAVYGATKAFVLSLTEAL
                     AHESRDSALRVLAV"
     CDS_motif       20502..20591
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ME763_RS00080_0001"
                     /evalue="6.20E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="ME763_RS00080"
                     /protein_end="41"
                     /protein_start="11"
                     /score="18.9"
                     /tool="antismash"
                     /translation="VITGASSGLGEEFARQWAERGADVVLVARR"
     gene            21531..22142
                     /locus_tag="ME763_RS00085"
                     /old_locus_tag="ME763_00085"
     CDS             21531..22142
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Methyltransf_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025217.4"
                     /locus_tag="ME763_RS00085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00085"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_085568331.1"
                     /sec_met_domain="Methyltransf_3 (E-value: 4.4e-12,
                     bitscore: 44.4, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSTLVNRFRPVAVAAIAAVRRPLEVADPFAGVQAATRRHRRAHH
                     CGAFAYGEGSLPAAIVAAVGARRIVEVGTALGYTALAMAHAAPGARVETIEMDPDHVRL
                     AREQISAHRMDDRIDVLPGTAEAVLKTLESGSYDVAFFDGFTPTDEVVRELHRVLRIGG
                     TLIAGNLILGPDRAVTSHLGDTSRWRTHSFGETALCVRLA"
     gene            complement(22259..22426)
                     /locus_tag="ME763_RS00090"
                     /old_locus_tag="ME763_00090"
     CDS             complement(22259..22426)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103121.1"
                     /locus_tag="ME763_RS00090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00090"
                     /product="hypothetical protein"
                     /protein_id="WP_164932666.1"
                     /transl_table=11
                     /translation="MLGIVAAVLFFVSFLVNAAEISTNHTFSSVNIMLLGLTALALHVA
                     GIGSGWSRRR"
     gene            complement(22479..22802)
                     /locus_tag="ME763_RS00095"
                     /old_locus_tag="ME763_00095"
     CDS             complement(22479..22802)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524367.1"
                     /locus_tag="ME763_RS00095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00095"
                     /product="hypothetical protein"
                     /protein_id="WP_085568330.1"
                     /transl_table=11
                     /translation="MAPKIERIEFLRAVRQLRRVRSFYAAGVLLWAGSTVWSGRQTPGS
                     REMWVSVLLLAVFTALLVTAGLSLRRLAVPATGRPAHHAAPHRTTGSRHAHTQTHAHAH
                     AHA"
     misc_feature    complement(23011..23023)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            23017..23553
                     /locus_tag="ME763_RS00100"
                     /old_locus_tag="ME763_00100"
     CDS             23017..23553
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005307354.1"
                     /locus_tag="ME763_RS00100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00100"
                     /product="hypothetical protein"
                     /protein_id="WP_085568329.1"
                     /transl_table=11
                     /translation="MPPSLASWPASGFRRPPLRERWRRALNDHTVPAQRSLMAAWLGFG
                     CTFGAARLITHGIRGGWLPWGNISAGRTHLHHYNFGIATLAGIGLVAVRGDEAYVGHPG
                     IGALYGAGSALIADEFALLLDLKDVYWARQGRISVDVSLGILSALGLYLTAVPFWHEVT
                     KVTRDHLQGRPADAA"
     gene            complement(23633..24076)
                     /locus_tag="ME763_RS00105"
                     /old_locus_tag="ME763_00105"
     CDS             complement(23633..24076)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010470687.1"
                     /locus_tag="ME763_RS00105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00105"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_085568328.1"
                     /transl_table=11
                     /translation="MSPRECSITDTLSLVGERWALLIVRELSHGVRRFGGIAANTGAPR
                     DILTTRLRKLEATGIVRRELYSAHPPRYEYHLTEAGAELNDVLLTLMAWGDRHLNAEDP
                     PMRFQHACGHRFEAAVVCAHCGGPAREQLHSPSGRGVITEPTG"
     misc_feature    complement(24139..24153)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            24270..24986
                     /locus_tag="ME763_RS00110"
                     /old_locus_tag="ME763_00110"
     CDS             24270..24986
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324837.1"
                     /locus_tag="ME763_RS00110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00110"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_085568327.1"
                     /transl_table=11
                     /translation="MERAGEVGGTFCHLPSGGIGLTPLSPARADALAARLAGLGYSLPY
                     VSADRDTAAAFAKAWQRYAGVEAAVRVRLCLYRLREPTPLRPVPAGRGRPVGEHSGDRD
                     QLMDWCQEFAADVEEDVTIDAGTWAGTRFARKRYTFWESPDGVPVSMARVNPMPAGVTQ
                     VDPVYTPARFRGRGYAGAVTVEVSRAALAAGAESVVLFTNAANATSNALYQRLGYVRVT
                     DWAVYDFTQPRPRPQP"
     gene            complement(25136..25798)
                     /locus_tag="ME763_RS00115"
                     /old_locus_tag="ME763_00115"
     CDS             complement(25136..25798)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072682.1"
                     /locus_tag="ME763_RS00115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00115"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_085568326.1"
                     /transl_table=11
                     /translation="MGTEIYFSNNHRDLCVQQGTGAGFQFEFSCSRCWDTWRSPFEPFR
                     AGQMAGWLSRGVNAAWSVIGGSTGQSVTNAADGLAGANFGSQRDAAFTRAIERAQGHFN
                     RCPRCTSYVCARCWNQGQGLCLTCSPDTAAEAQAAQQRGLNDMVAQRAYDVGQQQGTGY
                     DVTTPRQLVCPNCRTETRGGAFCHGCGHHLAQPVSCSACQQSLPHDAAFCPSCGARR"
     misc_feature    complement(26022..26037)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.12"
                     /tool="antismash"
     gene            26060..26860
                     /locus_tag="ME763_RS00120"
                     /old_locus_tag="ME763_00120"
     CDS             26060..26860
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS00120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ME763_00120"
                     /product="hypothetical protein"
                     /protein_id="WP_085568325.1"
                     /transl_table=11
                     /translation="MASPRSLNTATAWLVRLLSALTLVAGGVVFFSGTAEAATICGNVS
                     VPPGYVITSESLTASCTGGYLTETIQPPSNGLAVCLNGPIPSGYAVTSIYTTNNCGPYQ
                     TGRINTVTNGMRICGNSNDSLPNGYVITSEGPDSTCSQWYGETVNVASNGIAVCGNSPI
                     PANYVITSSYQNAACGIYLGARLNTASDGMTFCGNSPIPTNYVITANFQISSCGQYLGG
                     RLNVAYNGIIACADSPTPPGYWVSANGIQSSACSPYQAERLNNS"
     misc_feature    26111..26113
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(27085..27558)
                     /locus_tag="ME763_RS00125"
                     /old_locus_tag="ME763_00125"
     CDS             complement(27085..27558)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010356686.1"
                     /locus_tag="ME763_RS00125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00125"
                     /product="hypothetical protein"
                     /protein_id="WP_274505975.1"
                     /transl_table=11
                     /translation="METSMVRPEPLTVLPACVWSDTERDVIRLGHISRAMEGKWHVVSG
                     GDTVLLLRSWTGHAIYRAEFGPVDASEGGGWRIVRAEAERDPDRYRDFGADFDAVMLEL
                     VLRTYALSEPAAELRTRMVSLVADGTGRTNAPSPLVQMSLLGMRTDPRSADRP"
     gene            complement(27671..27799)
                     /locus_tag="ME763_RS00130"
     CDS             complement(27671..27799)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS00130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_274505976.1"
                     /transl_table=11
                     /translation="MHATSVAPADSAVPAGTRQHSRHPRFHPPHGLARHAGDVIAP"
     gene            27794..28282
                     /locus_tag="ME763_RS00135"
                     /old_locus_tag="ME763_00130"
     CDS             27794..28282
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012381053.1"
                     /locus_tag="ME763_RS00135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00130"
                     /product="DUF5990 family protein"
                     /protein_id="WP_085568323.1"
                     /transl_table=11
                     /translation="MHLHIEAHTLPGRNCGPGSGFPGISGIEVAVQRKDRPAELLDPQP
                     GDAPTATWTLPCTFTADGELRGPYVQNRLGGRFVYLSWLGRRPGEEVSRMFRRAKLMLD
                     EVAPRVLDEARLSGVLVARLALTDAQGGPLCGRVPLPAVVWSAGEPSDAFPGRAGRRP"
     gene            28591..29004
                     /locus_tag="ME763_RS00140"
                     /old_locus_tag="ME763_00135"
     CDS             28591..29004
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS00140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ME763_00135"
                     /product="hypothetical protein"
                     /protein_id="WP_085568322.1"
                     /transl_table=11
                     /translation="MQFRTKLAVVATAGLLASGLAFAGEAQAATGSPSANVSPKCSNSY
                     GALRAYYLSGYSGPCEEFWATWHDTSGITFSNGVTVTGGQVWSAENDSWRNANMYSGAW
                     GQGNLHIQYAGTSSNNLKGLGLLNSLSWTPDWN"
     gene            29193..29801
                     /locus_tag="ME763_RS00145"
                     /old_locus_tag="ME763_00140"
     CDS             29193..29801
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ME763_RS00145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ME763_00140"
                     /product="hypothetical protein"
                     /protein_id="WP_143657454.1"
                     /transl_table=11
                     /translation="MIPKPHRLGRVTGPLLLAAVLMGAATACDGPPTARPHPGAGHPTV
                     SAADMPLPARVPVTSVGASPTAWQLPMDAYQYTPAQSAEIQGAVYSLANSCMRDLGYST
                     DLPTRLRPGPDHNAFRYGPVTDAQAAQGYRWMLRKAAPNGAGALNPTSEEYGALLGKSR
                     QGRNRRPVPTGGCLGSARGALDSRGGRVAPPRRDPRHRR"
     gene            30171..30842
                     /locus_tag="ME763_RS00150"
                     /old_locus_tag="ME763_00145"
     CDS             30171..30842
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057321.1"
                     /locus_tag="ME763_RS00150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00145"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_085563736.1"
                     /transl_table=11
                     /translation="MISRLPLDQQLESLRSVLSRNHVLTEVLARTAALGLPGWYVTAGC
                     LFQTVWNVVTEKPPTSGIQDYDVFYFDDSDLSWEAEDAVIQAGREVFADLPAEVEIRNE
                     ARVHLWYEDKFGVPCPPYDSAEAAIDNFAATTCCLGVRVEMDGRWRVYAPHGLSDVFNL
                     VLRPNPVFAPRFVYETKAARWQEEWPELTVLEWPSTEITVTSDLGRVRDRIPGDRLNNH
                     R"
     gene            complement(30875..31669)
                     /gene="istB"
                     /locus_tag="ME763_RS00155"
                     /old_locus_tag="ME763_00150"
     CDS             complement(30875..31669)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="istB"
                     /gene_functions="other (smcogs) SMCOG1151: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477162.1"
                     /locus_tag="ME763_RS00155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00150"
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="WP_085563737.1"
                     /transl_table=11
                     /translation="MSLPRQRGLTEQAATTAVDQACRMLRLPTIRSQFPDLAETASREQ
                     MSYLGFLAELLLAECDDRARRRSERRIKAAGFPRDKSLRKFDFDANPNIDAAMIHTLAK
                     CEWIKKGLPLCLIGDSGTGKSHLLIALGTEAAMAGFRVKYVLATKLVNELVEAADEKQL
                     TKTIARYGRVDLLCIDELGYMELDRRGAELLFQVLTEREEKNSVAIASNESFGGWTKTF
                     TDPRLCAAIVDRLTFGGNIIETGTDSYRLATTRARAEQQSLG"
     gene            complement(31681..33306)
                     /gene="istA"
                     /locus_tag="ME763_RS00160"
                     /old_locus_tag="ME763_00155"
     CDS             complement(31681..33306)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="istA"
                     /gene_functions="other (smcogs) SMCOG1213: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123889.1"
                     /locus_tag="ME763_RS00160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ME763_00155"
                     /product="IS21 family transposase"
                     /protein_id="WP_085563899.1"
                     /transl_table=11
                     /translation="MPKSKVDLYAAIRRDARTGMSTRALMRKYGVGYETVQRALISALP
                     EPRKKMRPRATRLDPYKPVIDAILKADLTAPRKQRHTVKRIYDRLLDEHNAVGISYQMV
                     RGYVAGRREEIRLQAGKGVVDAFVPQTHRPGAEAEVDFGDVAVKLAGELVTCYLFAFRM
                     SYSGKAVHRIFASAGQEAFFEGHVHALNVLGGAPTGKVRYDNLRAAVAQVLGLSRRRVE
                     AERWTAFRSHYGIDALYCQPGLRGAHEKGGVEGQIGWFRRNHLVPVPEVDTLAELNEMI
                     DRWDQEDDARRIRSRPHTIGEYFAVEQPLLAPLPEEPFETGRLSTPRVDRYGQICVRMN
                     RYSVPVRLIGRTVRVMLHASELVVYDGREEVARHERLIARDGSRLDLDHYLEALIRKPG
                     ALPGATALDQARAAGRFTPIHDAWWEAAVKAHGERDGTRALIEVLLLSRHLPHEHLVTG
                     LAAALKTGALTADAVALEARKAADADTRPDEPQQSTTAVGQTRTLPLPATVRAHLPLDK
                     RPLPSVAHYDQLLRLRRTDRPTPS"
ORIGIN
        1 gggcaccagc gggggcagtc gcagggccgg tctactcgga ggtgccggtg aactgagggt
       61 ccttcttctg gttgtagatc tccttgccgg ccgcgttgta ggcatggacg tacgaagtcg
      121 acatcgcggc gatcaacttg gcgggggacg acccggtgga gaaggacgcc gtgtagaaga
      181 acgcgccacc tgccatgacc gccgggtact gcttcgggtc ctcgccatag ctgacggtga
      241 tcttggctac ggcggttgtg taatgtccgg cgccgagtga gaggtaccgc cccttcccgg
      301 ccgactggcc gacggcgtcg aagtactcca cgatgtggcc ggtgccccac agacggtcgt
      361 tgatgaacgt cggcgggacg tccgggctgc tgccccgctc gcccttggtc tggcactgca
      421 cgtactgccc ggccgagtcg acggcgatga ccgtgccgtc ccagtccttg gaggcggcag
      481 gggtacggac ggcgatcacc gggtggaatc tcccggcctc cgatcccagg caggaggaca
      541 ggatcctgtc gacggcgccc gccttgatcg gggtcgtggt cacgctggtg acggtaactg
      601 cgggcggcgc agaggccgaa ggcgccgagg acggcgtcgt acccgtcccg gcgttcgagg
      661 agccccggct cggaccaggt gacgcagcgg cgctcgtcgg acttccacca ctgccggcct
      721 gggccggctc ggcggccctc tccccaccga agacgctcac cgccccgacg ctcaacgccg
      781 cgacaccggc ggcgatactc aacggcagtc cccacctgcg caccagcgaa gtctgctcgt
      841 cctcttgatc gatcttcatc atcaggtcct ctcgggtccg ccggtgattc ggcagagcac
      901 gctcgggggg aggcgcgggc ataccttgcg tgtcattcat cgcgcgacct cctccacggt
      961 gacgggattc ttcgaagtgg acgacgtcgc aacgcccggc ctgccggcga gatcggcccc
     1021 cagcctgcgc cgtgctcggt gcagtcggga cttcacggtt cccaccgcca ctcccagcgc
     1081 cgtcgcggcc gcctgctgat ccaggcccga ccacatgcac agctcgacca cctcgcgttc
     1141 gtggcgcggg agccgggcca gcgcccgatg gagctgcgac atccggcgcg cgtcgtcgac
     1201 ctcgccggcg acacggtccg cgtggtcacc caccgactcg tcatgtgaga cgagccgccg
     1261 cagcaacgcc tcggcccgcc gtagccgccg cctggtgttc gacagcaggc gctccgcgat
     1321 gcccagcagc cacggcaggg ccgaatcgcg gtccagcgcg acctccgacc gccgccgcca
     1381 ggcatgaagg aacaccgccg aggtgagatc ctcggcctcc gcccagtcgg ccgtccgccg
     1441 gaacaggtgg ttgtagaccg tcttcgcatg acggtcgaag atccggccga aggcgtcgcg
     1501 atcgccgttg accgcccgcg cccacaactc ccggtcggat acccctccga cagctgcggc
     1561 cggaccgacg tcgttcactt ccatgccctg tatgtgtccg gcacccgacc gaaggttccc
     1621 gctgaacctg ctcctttttc acccgtcccg tcggtgccac ggccgggcgg cagggagcgc
     1681 tgggtccggg tgccgctcgg tagcagccgc aggcgccgcg cgaccgggcc ccctccaagg
     1741 cgaaggccct cacagatcac gccgcgaagc gggaacctag cgcgcttgat caccatcact
     1801 tcatgtacag atcaccttat gagcagtcag gttccaggcc gcgtagcggc cttggaaggc
     1861 tgcggcggtg gtttccaggt ccggaatcga cgtagaaaag tcaggtactt acacgtgcat
     1921 gagcgcaagc cgcaccggcg gctgtcaagg attctcgcgg caggagtgct ggctgccgcg
     1981 ggagtcgcgg ccgcctcccc ggccgcccag gcggtaggac atcggacggc ggccgacagc
     2041 cgtcagcacg cctttgagca ggccgcggcg gactacgacg tcccgctccc cgtcctcctc
     2101 gccgtcgcct atcacgagtc cgcctgggat gcccatgccg gtgaacgcag taccggcggc
     2161 ggctacgggc ccatgcacct gaccgacgtg acgaccggga tgctggccgc gggcgacgcg
     2221 ggtgcggtcg gccgtgccga cctccccgaa ctggcctccg ctccgtccct gcacaccctc
     2281 caggccgccg cccggctgac agggctgccc gggaagcgac tgcgcgcgga cgacgccgcc
     2341 aacatccgtg ggggtgccgc cctcctcgcc tcctacgaga agagcgcggt cggcagtacg
     2401 ccgaaggact cgggcaagtg gtacgccgcc attgcccgtt acagcggttc ctccgggcag
     2461 cgggcggcgc gagccttcgc cgaccgggtg ttcgccacca tcgagagcgg cgcgcaggag
     2521 accacccggg acgggcagca catcgaactg cccgcctccc cgagcgtcca gccggccgtc
     2581 aagcaactgt ccgtgctgca tctgagagcg acggccgcga caggcgacac cgagtgcccc
     2641 gccaccatcg actgcgcctt cctgccggcc tcggcggcca acgggcaggt gtccgaccgc
     2701 cccgccaacg ggatcaggat cgactccatc gtcattcatg acacggagtc gtcgtacgac
     2761 gccgccctga acaccttcca gaagccgggc ggcgggtcgg cgcactacgt catacgctcc
     2821 tccgacggcg ccgtgaccca gatggtgccc accaaggaca tctccttcca ggcgggcaac
     2881 tactcgacca acctgcactc gataggaatc gagcacgagg gatacgccgc cgcgggcggc
     2941 acctggtaca cgcagaccga gtacgagacc agcgcggaac tcgtccggta cctggccgag
     3001 cgcttcggca ttccgctgga ccggcagcac atcatcgggc atgacaacgt gcccgggccc
     3061 agctcggccc tcgtctccgg catgcactgg gacccgggcc cgtcctggga ctgggagcgc
     3121 ttcatgcggc tgctgcacgc cccggtgggc ggccggcacg gcgtgggccg cgtgggctcc
     3181 gtggtcacca tcacccctgg gttcgcccgc aaccagcaga ccgtacgggt ctgtccgtcc
     3241 gacgacccca ccggcgccac ccccgagtgc accgagcgga cccagccctc cgacttcgtc
     3301 tatctgcgca ccgcgcccag cgccaccgcg ccgctcttcg gcgaccaggc catccatccg
     3361 gacggcgtcg gcagcgacag catcaacgac tggggcagca ccgcggcggc cggacagcag
     3421 ttcgtcgtcg ccgaccggca gggcgactgg acggccatct ggtacagcgg cacgaaggtc
     3481 tggttcctca acccgcacgg ctgcaacacc acgcccgccc gtgatgtgac ggtggtgggc
     3541 gccgccggta cctcaccggt ggcggtgtac ggatcgagct acccggacgc gaacgaatac
     3601 cccgccggac tctccccctc cacccaggcc ccgctgtcct tctacaccat ccccgtcggc
     3661 caggcctacg tcaccaccgc cgcacccgcc cccaccgacg actacttccc ctccaccggc
     3721 cgggtcgtca ccggagggaa gagcatgtac accatccagt acaaccaccg cacagcactg
     3781 gtctacgcct ccgacgtcag cgcacggtaa gcatcgggcg gcaacccgcc gcggcggtcc
     3841 ggggacggag tgcccggacc gccgtagcgc gcggatcagg tgagccggac ggtcggcggg
     3901 gcggcccgcg ccgaagtggg cgatgagggt gggccgtccg gcctcgcggc ccgggtcgag
     3961 cgcggaacac agggcaagca gttcggtccg cgtgcggtcc gggccgactt gcgcctcgcg
     4021 ctccgggatc gcatcgaggc cggcgcccct atgtacgagg atccggatgt acgaggatcc
     4081 ggcgatctcc agccggatcc tgtccgtgca tcggcagggc ttccggcacc tcctcgatga
     4141 gccgcggtcg gcgacacgtg gacggcgtcg tcgccgcggt cggcgggaag aacctggggc
     4201 gcccgtccac gccggacgag gtccaggccg tcgcctccgc cccctcgccg caatgcctcg
     4261 gcgcgcccgt ggccgcggtc ctgacaccgg ccgggcggga ccgggccgga acacggtggc
     4321 gtgttccggc ccgtgccggg tcgggcgcta cccccatgcc cggtggcaga ggcccacgat
     4381 cttggaggac acgattccgc ccgcccggcc gcacaggaca cgcatctgtc cggaacgaac
     4441 ccgcggcgcc ttcgccgccc gccggggcgg cgaaggccgg gaccgcgccc gcggctgaac
     4501 gaagtgccgg gaggggcggg cgggccggac acggtgtgtc ggtcgtcgcg agggcgtggt
     4561 gctggtgtgc gacccgcccg cgggcgcctc ggtacggcgt accggggcgg ccccggcccg
     4621 gtcatgcccg ggcctgccgt gagaccggtc gggcccgatc cgcaccagcg cggaatcctg
     4681 ccgcggaggc acccgcgaac cggtcggcag cggagcaggg cgggcggaga cggccggacc
     4741 gcgtacgccc tgcggacgac cgtccgccga cgggatgccg ggcgccaccg tggtgcagcc
     4801 cgtgacaccc agcaggacca ggaccacaat gatcagcggg cgaaatgaca ccggcccaca
     4861 gtgcgccacc gcgagcgtcg gcgggccgta acacgaagca actcacccca aggaacgacc
     4921 ggtcgagctg gattgaccac gtagggcacc tgatccgagg gaccagtcaa ctccctacat
     4981 cccggttccc cgcatcccgg tgcggtgcac gaggccgttc aggatgaggg cgaggcccgc
     5041 ctcgaacgcc gactcatgat cgatcaccgg catgtcggcc ggcagatccg cgtcgtcacc
     5101 ggggccgggg tctgcctgct cctccaggac gctgccgacg gtgaaacggc cggcggccag
     5161 catggccatc tgtgcgtcgt gctcgggcac gccggaggcg acgaggaact ccattttgcg
     5221 gcggagtcgg gcgagatcgc cggtgggggt gctgcccgcg tgcagccgtg cgccgtcccg
     5281 gcgcgtcagc agggtgcgcc ggaagctgcg cgtgttgtcc gcgaaccagt cgtgccagtc
     5341 gtcgccgggt gacggcaggg gcgcggtcgt atggggttcc atcgccgctt ccgccatggc
     5401 ggcgaggagg tccttcttgg tgcggaagta ccagtagagc gacggctgct ccacgttcag
     5461 tcgcttcgcc agccgtctcg tgctcacggc gtccagcccg acctcgtcga gcaggccgag
     5521 ggcctcggtg atgacgactg cgcggttcat cttggtcacc ttgacaatct atcgctgata
     5581 gatgactctg aacaggaatc tttcactgat agatttgagg ggacggcatg gcggagggat
     5641 ggggcgagcg gcccctgcgg gttctcgtcg ccggtggggg aatcgccggg caggccctgg
     5701 ctttctggct cagccggggc ggccaccggg tgaccgttgt cgaacgcttt ccggcgctgc
     5761 gggccgccgg ggcccaggtc gatctgcgcg ggcagggcat cgaggccgtg gagcgcatgg
     5821 ggcttctcga cgccgtccgg agcaagctcg tggacgaggc gggcgtcgcc ttcgtcgacg
     5881 cctgcggcag ggccagggcg acggtcatgg ccaacacctc ggggcggggc cggcagaccc
     5941 tcacttccga gtacgagatc atgcgcgggg acctggtgcg catcctgcac gatgcgacga
     6001 gggacgatgc cgagtacgtc ttcggcaaga gcgtggacgg cttcgaacag gaggaggaca
     6061 aggtcgtcgc acacttctcc gacggctcct gcggcgagta cgacctcctg gtcggcgccg
     6121 acgggcaggg ctcccgcatc cggcgggcga tcctcccgga gggcttcgac ccgtaccggc
     6181 gcctcggcat ccacatggcc tactggttcg tcccgcgcat cgcctccgac agcaacatcc
     6241 gggacaccta catggtcccg ggcggccgcc agatcatgcg ccgcagccac aacccgaccg
     6301 agacacaggt gtacttcgtc ctacgggaag gatccgaggg tgcctcggcg atccaccgcg
     6361 cgcccgtcga gcgccagcag gagttctggg cgagcaggtt ccacgacgcc ggatggcaga
     6421 ccgaacgctt catcgagggc atgaggacca gcccgttctt ctactcccag gagatcgtcc
     6481 aggtccgcgc cgacgcctgg tccaagggcc gcgtggtcct ggccggtgac gccgcccact
     6541 gcgcctcccc ctacagcggc atgggcatct ccggcggcct ggtcggcgcc cacgtcctgg
     6601 ccggcgagat caaccgccac cccggcgacc taccgaccgc cctggcgaac tacgagagcg
     6661 cgctgcggcc cttcgtcaac aagatccagg gtcaggtcaa cccgcgcctg ctgcgcctgg
     6721 ccatgccgat gacccggcgt gccatcgatg ccttccaggc caccaccgca ctggcctgcc
     6781 gcctgcacat ccccgacctc gccgcgcgcc tttcgaagga ggatcgcgga ggcacctggc
     6841 ggctccccga gaacccggcc ccgaccacca cactctgaag gcgaccgagc ggttcgtacg
     6901 gagggccgtc gcaagtgccc ttgaccgggc ggcccgttcc ccgcaccacg agggggcgcc
     6961 ccctgcgtcc ccgcacctgc gggggtggcc atgccgtcgg gtacgtcctc ggcaggtaga
     7021 accacggcgc ggtaagtgcg gtgcgcctcg gctgctgtcc gaccggctca ccgaccgcct
     7081 ggtggtgacc ggcgaggctt ggtccgccga ccgtggtgcc cggaccggcg atgggaggaa
     7141 gagcccctcg gccggagagt gcgcggcggt gcgggccgcc atggctccgc cgtgaagtcg
     7201 tcgggggcgt ggtgatctcg gcgaagccga gccacgcttc gctccacggc gccagccttg
     7261 ttgtcgcgtg agcgggcccc atgggcgcgg tgcgccgcgg attccggacc ggcgtgtccg
     7321 cacgcctcac gccctggtgg atcccccccc aactccccca ccccacacac cgcacacgcg
     7381 cagcgcgtgt caggcaccgt gcgcggctcc gccgagcgcc gccgtcctcc gcacgaagtc
     7441 gccgtacgcg aaagccgtac cagcggcggg gcgaccgcaa cgctggtggc ggtggcggtg
     7501 gcggtggtca gacgactcgg ccgagccgtg ggccgccccg ggcgcgcagg cgtctgaaga
     7561 aggccaggac gcccgcggag ccgtcggccc aggtggcact cggcccggtg agcccggtgt
     7621 ccgggaacac gggccgggac caggtgccgc cgctgcggcc caggatgagc agggcgatgg
     7681 tctcggccgt ctcccagaac tcctcggacc cggacgcctc cgcgacatcc accatcagct
     7741 cgcccacccc ggccagcccg cagcactgcg tgacgagcgg catcctcggt gccagtgcgg
     7801 cgcaggcgcg cgcggaccgt tgggccaggt cgaggtgtcc gggttcgtcg aggcggtcgg
     7861 cggcccggac gagtacggtc ccgatgccgg ccaggccccg gcaccacgag ccgtagcggc
     7921 gtgtcgcccc tggcccggtg gccgccgcga tgatgtccgg tgtcacggca gccaggtggg
     7981 cgccggcctg ctcggagcgg ctgatcgcgt ccatgtcccc ggtcacgccc ccgtattcga
     8041 ggaggaagca ggccacgccc gcctcgccgt gggcgatgcc ttcgcgcagc gcggcgcggc
     8101 cggccgtgtc cgtgccgccc ggggtcagcc gggcggtgcc cgaggccagc atccggtcgc
     8161 agtcggcggc gacggcgagg tgccggtgtg cggagtgccg gtgaccggat cggagggcga
     8221 ggcgggccag caggagtcgg ccgaggccga tcccggcggc gcccgcgatc aggtccgcct
     8281 cgggcggtcc accgtccggt gcgcggcccg gcagggcggg ttgcccgggc agcgggtctt
     8341 cgtacgtccc cgccgctcct gctgtcaact gggcctgggt caggaagagt tcgacgccag
     8401 tgcgcccggt gtagaagccg ggtgggaggt tcctcgactg ttccgcggtc caccgcgtca
     8461 gcgcggtgac ggtcgagcgc acgcggggcc ggtgcaggtg gtggaggagt tccagtccga
     8521 gtcccgagct gccgccgtag acgtcgatcg aggtggggac gttcagtcgg gcggcccgtt
     8581 ccgggtcaac gatcgcgctc gcctcatcga cgcagaacgc ggtcgtgtgc tcgatgatct
     8641 cgtccagcag gtcgtcgtcg atccggggcc gtacgggccg gcgtgtggtc ccggccgtac
     8701 cggccgtgcc ggtgcgcagg cggtcggcgg tggcggtccg ttcggccggg tggaagctca
     8761 ggaggccgga tatccgtgac cggatctccc ggtgggcggg cccgggcagt gcccatgcca
     8821 ggcaggccag ggtacggtcc cggttgaccg tgtggtcgct gtcgacgatc accgggtcca
     8881 tgccggtggc ggcgaagaag agggtggcgc cgagggcgta gtagtcgtcg gcgggggcgg
     8941 ccgggccggc cgtccgcaga accggcgcgc cgtacccggg ggtcgccccg cccggaccgg
     9001 cgccgtcccg ctcgctgatc ccgaagtcga tcacgtggca gtggccgggg cgggaggcgt
     9061 cgagcacgac gttgtcgggc ttgagatcgc gcacgaccac gtttcggccg tggatcgcgt
     9121 ccaagatgcg aaggagccgg gaggccaggg cggacagggc gcgctccggc cgggtgccgt
     9181 cgtcgcgata cgggccgtcg cgcaggacct cccggcgcag gtcccggtcg ccgcaggcgc
     9241 tcatcaccag gtactcgtcc gaccggtgag cgaagtagtc cagcgcgcgg ggcacgcccg
     9301 tgacgccgtg gagggcggtg aggaccgcgc gttcgttgcg cagccggtgg cgggcgtctg
     9361 cgccggactc gtcctcgccc acgaaggccc tcgcctgttt gaccaccacc ggctgcccga
     9421 ggacgcggtc gaccgcgcgg tagacattgc cctgcggcga tcgcgtgatg ccggcggtga
     9481 ccgtgtagcg gccgccgccg aagtggggtg cggacggttc gtcgccgggt cgggaaccgc
     9541 tcgcgaaggg gtcctgggcc cagggcgggc accggtagcg gccgacggcc aggccgtcga
     9601 acatccggcc gtccgggccg gtcatgacgg attcgagccg tccgctccgg ccggtccggt
     9661 agtcgccggt gaaggggccg tagcggtagt agaccggtgc cctcggatcg acccgccggt
     9721 cgctgacgac gcgcgggccc tcccggtcgc gcagtacggc ggcgagttcc cgggcgatct
     9781 cggccaccgt gtcggccggg gcgtagacgg tgatggcctt gccgacggct ccggcgctca
     9841 ccgccccgga gttgaggcgg cgcaggacgt ccggatcgcg ggcgaacttg gcatggcaga
     9901 cgtgccggga cagcaccggc agtacgagca cggtcacggt gtcgaggtcg gcgggacgcg
     9961 ccgagacatg cagtttccag ccgtgttcca tcgccggcat ccgtggatcg ttcaggtacg
    10021 accacgtctc gtcggaccag ccgccgcggc cggcgatgga gacggccacc gctacgagtt
    10081 caggtcacac gagaagcggg tggtggcggt cacccagggg tcggcgaggc atgccgtggg
    10141 ctcgcggtcg tcacggtcgt cgtcctcgaa cacgatcgcc tcgtcgtcga tctccagcgg
    10201 acccgcgtcg cggaatccgc cggcttgaag aagatccggc acggctacgg gcatgtgacg
    10261 cctccatggt gtgtcgtgcg ctgagggacg gacatcggcc gacgcgggac gctggacccg
    10321 ccgggccgag gactgctgca caaaggtaag gaggggtacg cccgctgaca agaggtcaga
    10381 tcacccagcg gggccgcttg acctgccgtc atcgggacgg acgcagcgat gcggaagggg
    10441 aaggagggac tccctcttcg cgcggcggcg cgcccgggcc gtggtcccgc cgcgcgtgtc
    10501 gtttcacggg gcggggagcc gcccgcccgc tccgccgtcg ccggagcggg gacgacatgg
    10561 ccgccgaccg tacgccgtct ccgtcaagta ccggccgggc gggtcgcgtt cggccaggag
    10621 cgccgagcac ggaatgcgtg cgtccgccgg gcgcggtgtt cattgcggaa cctccggtcg
    10681 gcgccgtgcg gcccccgggg acgtgtccgg cgttcttcgt cccgggccat gccgccgatc
    10741 cggagccggt cgcggtgatc acctccgacg ccgcccaccc ggtacggacc ggttcgcccg
    10801 cccaggccgg gggtctgcag accggtgacc ggatactcgc cgtggacgga aacctcgttc
    10861 cggacgcccg ggtcgcggtc gcggccatcc ggtcccgaca gcccggaccc accgtcgtcc
    10921 tcaccctggg gcgcggcagc gggcgcctct gcctgtccgt ccggctgggc accggcctcc
    10981 ctcgctctgt tcccccgctg acagcgcgga tttcgcgtcg gcggcccgag tggcgcatgc
    11041 ggaaccggcg tacgccttca ggccgggcac ctcgcgcggg cggtcacacc gggctggagg
    11101 ggtgggccgc cgtgggtgag cggggtggcc aggcgcgggg ggataggagg ccgaggacgt
    11161 aggcgcgggc gaccatcgcc gggcgggtcg gcgcttcgag gaggacgcgg agccggctca
    11221 gatggtagtc cagggtctgc cgggacagcc gcagttcctc ggcgatgtcc gcgttgctgc
    11281 ggcccgccgc gagcagggcg acgatgcgta tctgggcggc ggtcagggtg ggctgggtct
    11341 gctggcgtcg acccaggtgg gtgacgacgg cccagacgcc ggtgacgccc ggcgccgtcg
    11401 cgccgacggt ggtcagccgg atgcgggccc ggcgctgcca gccttccccg tcgacgagta
    11461 ccgccgaggc gcgggcgctc ctgcgccggc cggcgatcag gtcgtcccag agtcgtagca
    11521 gggcgccgcg ttcgggtgtg tcggcgagaa gggaggcggc ccgcagcccg gtcagatcgg
    11581 agaggcggac gcgcaggatc tcggccgtgg cggtgccggc ctcgctcact cttccgtccg
    11641 gggcgaggcg gacgcaggcc agcccgctgt ggtcgcgcag tgcgcgtaag tcggcctcgg
    11701 cccggtgccg ttggtccatc gcccggacgt agtcggtgac gtcgacgtag atgcccgcga
    11761 cgcagcgttc ggcgccccag cggacgggaa accggtagcc cgccgcatgg gcgggagttc
    11821 cgtccgggcg gcggtaggtg agggcgtgcc gtatggactt gccgtcggtc aggacctgtt
    11881 ggtccatggc gaggaagcgg ccggcgttgg cgggttcgtc caggtcggac agatggcggc
    11941 cgatcaccgc gtcgcgtgtc gtcccgtaca ggtgggcgta ggcgtggttg gcccacacat
    12001 agcggccggc gccgtcgcgc atgaacgcgg cggccggggt gagttcggcg agggctccga
    12061 aggggttccg gccgggcggg ccggccggtt cgcccgaagg tgccttgcgt tccgtctcgt
    12121 ccacgggccc actccttcaa taccgcacga catgacgttg ggtgacgtct cgtgcgtaag
    12181 ccgtagcacc ccgggaacac gggagaaccg ggcgctctca ggctctgcac cggctgggtg
    12241 ctagcgcatc acaaaacctt cacatgacat caaccgcccg acgggatagg gcatttgcct
    12301 gaatggttcg cgtggtgcgg ccgccgggag gtgagctggg actggttcgc ttgaaggggg
    12361 agaaccggcg ggcgtgagtg ctcccgacat caagtgcccc gacatcgaag gagatgggtc
    12421 tacgtgagcc aggtgctgta cgtgcatgcc aagggcgggc ccccggtggg tcatgctctg
    12481 acacgggtgg ccgggcgggc cacggtgcac ctgctggcgc tgagcgggct gcccgtgggg
    12541 gtggccgagg acgcggcgcg gctgtgcgcc tctgtgatga cgccttcccg ggcggagcac
    12601 gcggacctcg tcgagctgat caccacccgc gcccgcgagg tgggggcgga cgccgtcctc
    12661 accttctcgg agtacgcggt ggtcgcggtg gccgaggcgt gccggcggct cggtctgagg
    12721 ggtgccgggg cggccgccgc tctcgcccgc gacaagcggc tgatgcgggc cacgtgggac
    12781 cgtcacggtg ttccacagcc ccgcttccgc cccgtcgcgg ggctcgccga gctggagcgg
    12841 gcgaccatcg aattgtcatg ccccttatta ctcaaggccg cgtggagcgc ggggtcgacc
    12901 gcgcaccaga tcatcgacgg gcccggacag gcgcggcacg cctggcaccg ttcgcgtcag
    12961 gtcatggcgg agtcggcaca actcggcttc gccgagatgc atgtgcgggg cgcgtcagag
    13021 gacttcatcg tcgaggagat cgtcaccgga cgggccgagg agtggttcga cggccccggc
    13081 tggggtgact acgtgagcgt cgagggcgtc gtcgtcgacg gcgatttccg gccggtgtgt
    13141 ctgagcgggc gcatgccgac ggtgtggccg ttcaccgagc gcgccggtat cactccggcc
    13201 gccgtcgaca gcggggccca gcgcaggatc gtggagctgg cccggcaggc cgtggacgcg
    13261 ctggggctgg agaactgcgg cacccacacg gagatcaagc tgggcgcgga cggccgtatg
    13321 tgggtcatcg agacggccgc ccggttcggg ggcgcgatga ccgtgccgca gatcgaggac
    13381 gtcttcggcc tcgacctggt cggcatgttc accgatcagc tgctcggccg ctcgcccggc
    13441 tggcccgcgc ggacgctgac gcccgcggac gccgagggcg cgacgggctc gctggtggtg
    13501 ctcgcggtcg acggcgaggg cacgccgtgg ccgcggcggc atctgtggga ctcctcgacg
    13561 gtggtccgca aggcgccgat cggtgccggc agcacgctgt ccgtggtccg ggagagttcc
    13621 ctccccgacg gctcgccggt ccccgtatac gaccccgcgg gcggcgccaa caccatggcg
    13681 gggctgtgtc tgctgtcggc cgaccggccg cagtccgtcg tacgcgactt caccgccctg
    13741 gtggccgcgc tgccggacat cctgccggtg gacgccgccg aggaggcacg cgcatgacgt
    13801 tcgcaccgga cgaggcccgt gccgccgatg cggcgggcga ccgtaccgtg gtcggcggca
    13861 atctgtcgct gccgctgttc cgcacgctgt ccggcgtgct cgccggacac ccgtatctga
    13921 aggtcgtggt ggaccgggcc gaggacacct ggcatctgct cgacacccgg gtgcacccct
    13981 tccacgtcga ctacatcgcc acgcgcgtcc tcggcatgac accgcgtcaa ctcgacgcgg
    14041 agctggacgc gttcaacgcc caggtgtaca tggcgcccga ccgccgcttc ctgctgggaa
    14101 tcctctcctt gcacagcgac gaggacgccg aaggcgccga acggcccttc ctcgtcctgg
    14161 agacgacgga ggcggacacc atgcacggtg ccctgctcca ggagttctac gactacgtcc
    14221 gccatcgcgt ggacgggcgc ctcccgttgc tgctgaaacc ggccaaccac ggccaggagc
    14281 atgagctggc cctggtcggc gacacccgta tcccgcgcat cctgagccag gagttgttcg
    14341 gcagccgcac ccggacctgc ctcaacccgg gcgtggcgga gggacgtctg cggtatttcc
    14401 gtagtccgca ggagtaccgc gcaggggtcg cgggcctcgg ctgggcggac atcgtcgcca
    14461 tggcgggcct gcccgacgac gtgccccggg tggccggatt catcaacacc cgccccacca
    14521 caccgctttc gcacaccaac gtgctggcct cgggctgggg tatcccgaac gcgatcgtcc
    14581 gcgacctgga cgccctggtg gagcggcacg gcctggacgg cgcctgggtc cgctaccggg
    14641 tgcgggagga cgccgtcacc ctcgaaccgc tgtcctgcgc cccggcgttg gagcggccgg
    14701 tctgggacac ccagcgcatc catatcggcg cgccgctcat cggggacgcg ccgatcatgg
    14761 aactgcaccg gctgcggctc gccgaccgcg acagctacgg caccaaggcc gcccacctcg
    14821 gcgaactgca ccatgtgctg gacagccgca ccgcggacct gacggccttc tacgcccgcc
    14881 cgcgcccgcc gcggccggat ctgctcgccc atctcggcac ccggctcggt gagcccgaag
    14941 cgcccctgga acggctccgg ttgacggccg ccgaacgcgt ggcccaaacg gtccgggcgc
    15001 cgcggggcgt ggcgctgccg ttccatctgc accatctcta tctgacctcg tcgccggcgc
    15061 tccaacaggg catcggcaag ctgaagttgg cgctcgaact cgacgcgctc gacatgatcg
    15121 acccgctctc gctggatctc cagcacctga tgcggagcac accgatgccc gaggaggtgg
    15181 cgcgagccat caccggagcc gtaccgcggc tggtggccga cggtcgccgc ctggtggtgc
    15241 gttcctcctc caacgccgag gatctgccag gtttctcggc agcgggcatc tacgactcgg
    15301 tgacgacggt acgcggcacg gagcagctga tggacgccgt catccatgtg tgggcgtcgc
    15361 tgctgtcgcc gcgcagcgta cggatgcggc accaggtcgg catctcgctg gacgacacct
    15421 acatgggggt gatcgtccag gagtacacgc cggccgatct cgggggcgtg ctggtcacct
    15481 gcaacccgac gcgccgggag gacttccgga acgtgtacct caactgcacg gccggttcgc
    15541 ccgagcgcgt ggtggacggc acggtcctgc cccaccagta cctgtacaac acggtcgagg
    15601 gcggtggccg tacggtcgcc gtcggatcct cgggcaccga cctgccggcg gacacgaggc
    15661 aatcgctggc cgaactggcc ctggcggggc gcctgttgca gtcccacttc agcacggacg
    15721 acccggacga cgccctggac atcgagtggc tgatgaccgg cgagggggcg ttccagctgg
    15781 tccaggtccg cccgtacgcc cgatgaggcg ccatgggccc gcgccgtggc gccgcgctcc
    15841 gcacgaggac ctgaccccgg cggcccgccg ggtgatccgc ctcaacaacg ggttccagct
    15901 gctgttcaat ctgctgtggt ggatgcccgt cttctacgcc taccagcgtg acgcgggcct
    15961 gtccgacggc cagatcttcg gcatccagag catctactac atcgccttct gcctcttcga
    16021 gatcccgacc ggactcgtcg ccgaccgcat cggcgcgcgc aactgcctgt gggcgggcgc
    16081 ggtggtcatg acggcggcga acctggtgcc ggtgttctcc ccctcctacc cgggcttcct
    16141 cctccacttc ctggccatcg ccgcggggcg ctccctgacg tcgggcgcgg ccagcgcctg
    16201 cctctacgac gggctgcgcg cggaaggggc ggacgcgcac tacctccgcg cggagggtac
    16261 ggcgcgggcc ctggggctcg cggcgaaggt cgtctgctgg ccgctcgtcg ggccgctgat
    16321 ggtgctggcg ccgcaggctc cgtacgtact gagcgcggcg agcgcggcgg gctcgctcgg
    16381 ctgcgccctc gccctgccac ggccggctcc gcgcaaggcg agcggggcga gccgcgcctc
    16441 cgggcggcgc gaggcggcgc tgctgcgcga caccggcgcc gcgctgcggg cccttcggtc
    16501 gtcgccgtgg ctcgccctgc tcatggtgca gggcgtggcc gtcttcacgc tgtcgcggat
    16561 ctgccaggtc aacctcttcc agccggtgct gctgcaccat ggcatcggcg agggcagcac
    16621 cggcagtgtg ctcgcggcga tgacggtcgc cgaggcggtc gcctccgcgc ggccccagtg
    16681 gctgggttcc cggctgtcgc ccacggcctg ggtgtccctg ctgagtgtcg cgctcgcggc
    16741 cacgctggcg ggcaccaccg tcggcggccc gtggacggtg gccgctctgc tctgcgtgtt
    16801 cgccgcgatc accggcttct gctatccggt gcagcgcaaa ctcatcaacg acgcgatccc
    16861 gaagaccgct ccgcgtgcca ccctgctgtc ggtggagagc atcgtggacc gcggggtgtg
    16921 cgccctggcc gcggtggccg cgggcgcctg tctggcggcg ggccggctcg acgccctgct
    16981 ctggcagtcg gccgccgtca cctgcgcgct gatcccggcc cttcatctgg cgctgcgccg
    17041 cgtgaaccgg gcggcgcgga cgcgcggggc gggtacggca accggcgcgg acgcgggctc
    17101 cgggcgggcg cggacgctcc cggccgacga gcccgtcgca ctgcccgtcg acgagggggc
    17161 cgccccgagg gcctgaaccg gggctcgggg cgggccggga gcacaccggg taccggctgg
    17221 gcggcccgcc ccgtccaccg tgcgcgcgcg atgtccgcgt cttcgcggga attcgcgcgg
    17281 cgtacacatg cggaacaggc tgtgcgtcgc ctgtgaagga ggcgtggggt tgttgtcgct
    17341 tgtgacccac gtgtatagcg caagcggtcg ttgctggggt tttctctgca tgtcactgcc
    17401 aaccccccat gtgatgaagg gaattgaaag accgtagagc cttgctctgc attggcatgc
    17461 ccctgccact ccggggtgtg tccttcatgt ggctcacacc ggccggcccc acaccgaccg
    17521 gaaaatcccc ccacggaaag agaagcctgc atgacccacg gcaacatacg tcgccagcgc
    17581 acgaccctcg cggtggccac cgccgtcgcc gctacggccg ccctgctgag cacctcgctc
    17641 accgcctcgg ccgccgcccg gcccaccgcc gactccgcac gcccggccgg tgcgcccgtc
    17701 gccctgtcgg ccgccgccca caccggtctc atccgcagcg cgcaggccga gctcgccggg
    17761 accgccaagg ccctcggcct gggcagccag gagaagctgg tcgtcaagga cgtcgtcaag
    17821 gacggcaacg gcaccgtcca cacccggtac gagcgcacct acgccggcct cccggtgctc
    17881 ggcggcgacc tgatcgtgca cacctcgaag tccggcagga cgcagggcgt gaccagagcg
    17941 tcgaaggcca cgctgaagct cgcctcgctc accccgcgga tcgccgcggc caccgcgcag
    18001 aagcaggccc tgagcctggc gcagaaggac cgttcggcga agcccgccgt cgaccgggct
    18061 ccgcgcaagg tcgtctgggc ggcgggcggc acgcccgtcc tcgcctacga gaccgtgatc
    18121 ggcggcttcc aggacgacgg cacgccgaac cagctgcacg tcatcaccga cgcggccacc
    18181 ggcaagaagc tcttccagta ccagggcatc gagaccggcg tcggcaacac ccagtacagc
    18241 ggcaaggtcg acctgacgac ggcgcagtcg ggctcgtcgt acaccctcac cgacgactcc
    18301 cgcggcggcc acaagacgta caacctggac caccagcagg acagcaccgg cacgttgtac
    18361 tcccaggaca acgacacctg gggcgacgga accacgtcga acgccgcgac cgccgcggcc
    18421 gatgccgcct acggcgcgca ggagacgtgg gacttctaca agaacacctt cgagcgcaac
    18481 ggcatcaaga acgacggtgt gggcgcctac tcccgtgtcc actacggcga ctcgtacgtg
    18541 aacgcgttct gggacgacag ctgcttctgc atgacgtacg gcgacggcga gggcaacaac
    18601 gacccgctga ccgcgctgga cgtcgccggt cacgagatga gccacggtgt cacctccaac
    18661 accgcgggcc tcgagtactc gggcgagtcg ggcggtctga acgaggccac ctccgacatc
    18721 ttcggcaccg gcgtggagtt ctacgccaac aacagctcgg accccggtga ctacctcatc
    18781 ggcgagaaga tcgacatcaa cggcgacggc accccgctgc gctacatgga caagcccagc
    18841 aaggacggcg gttccgccga ctactggtcc tcgtccgtcg gcgacgagga cgtgcactac
    18901 tcgtccggtg tcgccaacca cttcttctac ctgctgtccg agggcagcgg cgcgaagacc
    18961 atcaacgggg tcgactacga ctcgccgacc aaggacggct cgaccgtcac cggtatcggc
    19021 cgggacaagg cgctccagat ctggtacaag gcgctgacga cgtacttcac gtcgaccacc
    19081 gactacgccg acgcccgcaa gggcacgctg tccgcggcga ccgacctgta cggcgccgac
    19141 agcgccgagc acaaggcggt cgaggcggcc tggaccgggg tcgacgtgca ctgagccgtc
    19201 ccgttcccgc tcgaccgacg gtggcacccg ggcctgtggc ccgggtgcca cccgcgtttg
    19261 cgccgacccg gcccggtcgg ccgtcggctg acgaacagtg aactgcccgg ggcgggaccg
    19321 gtgcggagtc ggatcgccgg cttcggcgag aatctcggcg gtctccggcc tcgcgcacca
    19381 tacgtcggcg tcacgggtca gccacgctct ggccgcgtcc ggcgtgacgg ggtccgtcac
    19441 gggtgcggca ggtgccggaa ccggccaagt gccgcggtgg cgccggtccc tcaccggggc
    19501 cgggtgttga cggtgggcgc cgatctcgcg gcgcctgcga cgggtcggcc acggccgcgg
    19561 ccggttcgtc ctcgcccggc ggcatcccat cacaggactc ttgccggtgg cccccacgcg
    19621 gctcggcggc atggggcttc ggtcgcggag cgcggcggga tcgtcgcgtg cacttcaacc
    19681 ccgtccagca ttccggcagc gcgctcaggg agtgccgcgc aggccggtca cggagtgccg
    19741 cgcagcccgc tcacggagtg cagcgcaggc cggtcacgga gtaccgcgca ggccggtcag
    19801 caggatctcc agggccaggt cggtcgcctc cccgaccggt gtgtcgtcca gcagatcacc
    19861 gacggcgagc acggccaggc catggacggt ggagaaggcg acctgggcga ggcgcaccgc
    19921 gtcgccggaa cggacggcgc cggtccgctg ggcctcggcg atcacctcgg ccgcgatctc
    19981 cagactgcgg tgcccgagca cccggatctc ggcgtccggc tccacctcgt gcttggcggt
    20041 gaacatcagc tccagcagcg ccggccgctc ggtcgcgaac ccgacgtagg cgcgccccag
    20101 cgcggccagc cggccttcga cgggtccggg gcctccggcg gccgcctcca tgcgccggtt
    20161 caggtcggtg aaaccgtcgg tcacgagcgc gtccagcaca gcctgccggt cgcggaaatg
    20221 ccgggtcggg gcggcatggc tcacaccgag gtccctggcc agcccgcgca gggacagccc
    20281 gacggcgccg ctctcggcca acacttcctc cgcccgctcc agcagagcgg cccgcaggtt
    20341 gccgtggtgg taggagccct cggccatgct tctctcccga tgttgtcagt tgactacaat
    20401 gatgtcacgt gcctacattg gcatggccgg cccaccccga acgaccgacc gaagcggagc
    20461 cgcctcccat gcccaccatg tcctatcagg ggaccaccgc cgtgatcacc ggcgccagct
    20521 ccggcctggg cgaggagttc gcccggcagt gggccgaacg cggcgccgac gtcgtactcg
    20581 tcgcccgccg cctcgaccgg ctggagaccc tcgccgccga gctggagaag tggcactccg
    20641 tctccgccac accgatcgcc atggacctcg ccgagccggg cgccggcgtc gcgctgcggg
    20701 aggaactcgc cgcgcgtggc aggtccgtcc agaccttgat caacaacgcc ggattcggca
    20761 gccacggcgc cttcgcggag caggacccgg agcagatcgc gcgcatgatc cggctcaacg
    20821 tcggggcggt caccgagctg acccgggcct tcctgccgca gctggccgcc gacggccgcg
    20881 gcgcccttgt caacgtcgcc agtacggccg cctaccagcc caccccggcc atggccgtgt
    20941 acggcgccac caaggcattc gtcctcagcc tgaccgaggc gctggcccac gagagccgcg
    21001 acagcgcgct gcgcgtgctg gcggtgtccc cgggaccggt cgccaccgag ttcttcgatg
    21061 tcgtcggcag caggaaggcg atcgtcggcc ggatggccac ggcagccgac gtggtggcgg
    21121 cgacccgtag cgccctggag ggccgccgca ccccgtccag cgtcatcgcc gggctcggca
    21181 accgcatatc ggccacggcg gcccggctcg ccccgcgccg catcgccctg gccgcggccg
    21241 gccgggccct gggggcctga ccggccgaac ggagaacggg gacggcgcgg acgacggctt
    21301 tcggcccggt tcgtgcggcc cggttcgtgc ggcgccgttc gtgcggcact ggccgtggga
    21361 tcgtcggaac gcaagagact cacacgcaag agactcaata gctcgtacga ggaggggacg
    21421 aggagacgtc cgtccacgaa ccgtcccctc cacgtgcgtc tcgcctcaca tggcaccgta
    21481 tcgaagggcc ccggcgatga accggcccac tgacgacgca ggagcagacc atgccgagca
    21541 cgctggtgaa caggttccgt ccggtggccg tcgcggcgat cgccgccgtc cgccggccac
    21601 tggaggtggc ggatccgttc gccggcgtcc aggccgcgac ccggcggcac cggcgtgccc
    21661 accactgcgg agcgttcgct tacggggagg gttcactgcc cgccgcgatc gtggcggcgg
    21721 tcggcgccag gcggatcgtg gaggtcggta cggccttggg ctacacggct ctcgcgatgg
    21781 cccacgcggc gccgggcgcg cgggtggaga ccatcgagat ggaccccgac cacgtccgtc
    21841 tggcccggga acagatcagc gcgcaccgga tggacgatcg catcgacgtc ctgccgggca
    21901 ccgccgaggc ggttctgaag acactggaga gcggctccta cgacgtggcg ttcttcgacg
    21961 ggttcacccc taccgacgag gtcgtccgcg aactccaccg agtgctgcgg atcggcggga
    22021 cgctgatcgc cggcaacctc atcctgggcc cggaccgggc ggtcacctcc catctcggcg
    22081 acacgtcccg ctggcggacc cactccttcg gcgagacggc gctgtgcgtc agactcgcct
    22141 gagccgaccc accagtgtca cgccgtccgc ccgcgggccc gcagcctgag cagcggcaag
    22201 ggtggggcgg gcggccctcc ggtcggcctc ggcggactgt ggggtttgag gcccaccgtc
    22261 accttctgcg ggaccagccg ctgccgattc ccgcgacgtg cagggccagc gcggtcagcc
    22321 ccaggagcat gatgttgacg gacgagaacg tgtgattggt gctgatctcg gccgcgttga
    22381 cgaggaacga cacgaagaac agcactgccg cgacgatgcc gagcatgaca agcccctctc
    22441 ggtaggaagt gaaacccgta tgcccggccg acgcggtctc aggcgtgggc gtgggcgtgg
    22501 gcgtgggtct gggtgtgggc gtggcgggag cctgtcgtcc tgtgcggggc ggcgtgatgt
    22561 gcgggccggc ccgtcgcggg gacggcgagc cgccgcaggg acaggcccgc ggtgacgagg
    22621 agggcggtga agacggccag caggaggacg gacacccaca tctcccggct cccgggtgtc
    22681 tgccggccgg accacaccgt ggaccccgcc cacagcagga cacccgccgc gtagaaggaa
    22741 cggacgcggc gcaactgccg tacggcccgt aggaattcga tacgttcgat cttcggtgcc
    22801 ataccgagcc gggtaccccc gatgtgtgac gggcatcagg gtcgatcagc ccccgcacac
    22861 cgacgacgac cacgggcagc ttcgtcgccg aacggtccgg ccacgtgtca tccgggcgac
    22921 acaccggcat cagcctgccc tcttggtggt aggtctgacc ggtgtccggg cgcgagcgcg
    22981 acctcccggt cactcaggcc acgatcagga gtgacaatgc ccccaagcct ggcgtcctgg
    23041 cccgcgagcg gtttccggcg ccctccgctg cgggaacgct ggcgcagggc gctgaacgat
    23101 cacacggtgc ccgcccaacg ctcgctcatg gctgcctggc tcggcttcgg ctgcaccttc
    23161 ggcgcggcac ggctgatcac tcacggcatc cggggcggct ggctgccctg gggaaacatc
    23221 tccgccggcc ggacacatct gcaccactac aacttcggca tcgccacgct cgcgggcatc
    23281 ggactggtgg cggtccgcgg cgacgaggcc tatgtcggcc accccgggat cggtgccctg
    23341 tacggtgccg gttcggcgtt gatcgccgac gagttcgccc tgcttctcga cctcaaggac
    23401 gtgtactggg cccgacaggg acgcatcagc gtggacgtct ccctgggcat cctcagcgcg
    23461 ttgggtctct atctgaccgc ggtcccgttc tggcacgagg tcaccaaggt cacccgcgac
    23521 catctccagg ggcgcccggc cgacgcggcg tgagcgccgt gaaccggcac cggcgacgcc
    23581 ggtccatccg gctcagccgg tccgcgtctc cggctcgtac cgtcagcccg gtctatccgg
    23641 tcggttcggt gatgacgccc cggccggaag gcgaatggag ctgctcacgg gccgggccgc
    23701 cgcaatgcgc gcacaccacc gccgcctcga agcggtgccc gcacgcgtgc tggaagcgca
    23761 tcggcgggtc ctcggcgttc agatgccgat caccccacgc catcaacgtc agcagcacat
    23821 cgttgagttc cgcacccgcc tcggtcaggt ggtactcgta acgcggcgga tgcgcgctgt
    23881 acaactcacg gcgcacgatg ccggtggcct ccagcttgcg cagccgggtg gtcagaatgt
    23941 cccgcggcgc acccgtgttc gccgcgatcc ccccgaagcg ccgtacacca tggctgagct
    24001 cacgcacgat gagcagggcc caccgctccc ccaccagact caaggtgtcc gttatagagc
    24061 attcccgagg cgacatgact gcgagaataa cccggagccg gaccgacgaa gacgcgcggg
    24121 ggacggaccc gggggatcat cggcgtgcgt gatccgctcc acgtccggcc tgggggaact
    24181 cgcgcgtcgt acgtccgtgt gacggcgggt cgtcccgtgc cggatccggt cttcccacca
    24241 ggccgggtgg tcggggaggg tgaggctggg tggagcgggc cggtgaggtc ggcgggacct
    24301 tctgccacct gccctccggc ggcatcgggc tcaccccgct ctcccccgcg cgggcggatg
    24361 ctctcgccgc ccggctggcc ggcctcggct attcgttgcc ctatgtcagc gcggaccgcg
    24421 acactgcggc cgcgttcgcg aaggcgtggc agcggtatgc cggggtggag gcggcggtgc
    24481 gggtgcggct gtgtctgtac cggctccggg aaccgacacc gctgcggccg gttccggcgg
    24541 ggcgcgggcg gcctgtcggc gagcacagcg gcgaccgtga ccaactgatg gactggtgcc
    24601 aggagttcgc ggccgatgtc gaagaggacg tgaccatcga cgccggcacc tgggcgggca
    24661 cgcgcttcgc ccgcaagcgg tacacgttct gggagtcgcc cgacggcgtg ccggtctcca
    24721 tggcgagggt gaacccgatg cccgccgggg tgacccaggt ggaccccgtc tataccccgg
    24781 cgcggttccg ggggcgcggg tacgcgggcg cggtgacggt ggaggtcagc cgggcggcgc
    24841 tggccgcggg cgccgagagt gtcgtcctgt tcacgaacgc ggccaacgcg acgagcaacg
    24901 ccctctacca gcgcctcgga tacgtccggg tgactgactg ggcggtgtac gacttcacac
    24961 aaccccggcc ccggccccag ccgtagccgt agccgtagcc gtagccgtaa gggtcccggg
    25021 atcgtgacct cggccctcct gtgaaggccc aggtgtgtcg agtgttcgac gccggccgct
    25081 cggccgggcc ggcgcgtgtg gtgtccccgg acgatcgcgc ccggggacac ccgggtcagc
    25141 gcctggcccc gcaggagggg cagaaggcgg cgtcgtgcgg gaggctctgc tggcacgcgg
    25201 agcagctcac gggctgggcc agatggtggc cgcagccgtg gcagaaggcg ccacctcggg
    25261 tctcggtacg gcagttggga cagaccagct ggcggggggt ggtgacgtca taccccgtcc
    25321 cctgctgctg gccgacgtcg tacgcacgct gggcgaccat gtcgttcagg ccacgctgct
    25381 gggccgcctg cgcctcggcg gcggtgtccg gcgaacaggt caggcacagt ccctgcccct
    25441 ggttccagca gcgggcgcag acgtaggagg tgcagcgcgg gcagcggttg aaatgcccct
    25501 gggcacgttc gatggcacgg gtgaaggcgg cgtcccgctg gctgccgaag ttcgctcccg
    25561 ccagcccgtc cgcggcgttg gtcacgctct ggccggtgct gccgccgatg accgaccagg
    25621 cggcgttcac accccgggac agccagcccg ccatctgccc ggcccggaac ggctcgaacg
    25681 gggaacgcca ggtgtcccag cagcgcgagc acgagaactc gaactggaaa cccgcgccgg
    25741 tgccctgctg gacgcacagg tcgcggtggt tgttgctgaa atatatctcg gtgcccatga
    25801 cggccgtctc ccccacaagt cgatcccggc gaggagtgta tagccgtcgg ccgaaagcga
    25861 tccccgcgag gggcgggccg cggtctgccg cgaggacatc ggtcgggtgg cggaggtccg
    25921 gcccggccga caccgacgac ctcggcggcg ctgctcgcga cgccgctcgc gactgctcac
    25981 ggctgaatcg tgaccgggcg acgggcgcgg ccactaatct ctcgaacagc ctttccactc
    26041 gatcggaagc gagtcgcaca tggcctctcc cagatccctc aacaccgcca ccgcatggct
    26101 ggtgcgcctg ttatccgcgc tcaccctggt cgcgggcgga gtcgtcttct tctccggtac
    26161 cgccgaggcc gccaccatat gcgggaatgt ctcggtgccg ccgggctacg tgatcacctc
    26221 ggagtcgctc accgcgagtt gtaccggcgg ctacctgacc gagaccatcc agccgccgtc
    26281 caacggcctc gccgtgtgct tgaacggccc gatcccgagc ggctacgcgg tcacctcgat
    26341 ctacaccacc aacaactgcg gcccgtacca gaccggccgg atcaacacgg tcaccaacgg
    26401 catgcggatc tgcgggaact ccaatgattc gctgccgaac ggctatgtga tcaccagtga
    26461 gggaccggac agcacgtgct cgcagtggta cggcgagacg gtcaacgtcg cgagcaacgg
    26521 catcgcggtc tgcggcaact cgccgattcc ggccaactac gtgatcacct ccagctacca
    26581 gaacgcggcc tgcggcatct acctcggcgc ccggctcaac accgcctccg acggcatgac
    26641 gttctgcggc aactcgccga tcccgaccaa ctacgtgatc accgcgaact tccagatcag
    26701 cagctgcggc cagtacctgg gcggtcgtct gaacgtggcc tacaacggca tcatcgcctg
    26761 cgccgactcc cccaccccgc ccggctactg ggtctccgcc aacggcatcc agtcctccgc
    26821 gtgcagtccc taccaggcgg agcgcctgaa caacagctga tccccggcac ctcctcccgg
    26881 tccggcctgc cgccgacgac agcggccggg cggaccggga gtgatgacat cgccggcctg
    26941 cccggtgagc ggccggcccc gaggacggtc tccggggctc gggcgcccag gacttgtccg
    27001 gtcggtcacc caaaccgctt gcggcggggg cgggcgccgg aagcgacaac cgcgcggctc
    27061 ctccggtccg aggtgtgggc agatttacgg ccgatcggcc gaccgcggat ctgtacgcat
    27121 gccgagaaga ctcatctgca ccagagggga gggagcgttg gtacggcctg tgccatcggc
    27181 gacgagggag accatgcgag tgcgcagttc cgctgcgggc tcggacaggg catacgtacg
    27241 cagcacgagt tccagcatca ccgcgtcgaa atccgctccg aaatcccggt accggtccgg
    27301 atcccgctct gcctcggccc ggacgatgcg ccacccgccg ccctcggacg catccactgg
    27361 gccgaactca gcccggtaga tcgcgtgtcc cgtccagctc ctcagcagca ggacggtgtc
    27421 gcccccggag accacatgcc atttgccctc catcgcgcga ctgatatggc caagccgtat
    27481 cacgtcccgc tcggtatcgc tccacacgca tgcgggaagg acggtcaaag gctctgggcg
    27541 caccatggac gtttccacgg gcgagatcgt agtcgcccgc tttcccggcc gcgcagggcg
    27601 aggacgcggt gccggacccg ggcacagtgg cgtgacctgc ccgaacggtt cgggccgcgg
    27661 cggaccggat tcagggggcg atgacgtcac cggcgtgccg ggcgaggccg tggggcgggt
    27721 ggaaccgggg gtgccgggag tgctgccggg tgccggccgg gacagcgctg tccgccggag
    27781 ccacactggt ggcatgcatc tgcacatcga agctcacacc ctccccggcc ggaactgcgg
    27841 tcccggctcc ggtttcccgg ggatcagcgg gatcgaggtc gcggtccagc gcaaggaccg
    27901 gcccgccgag ctgctcgatc cgcagcccgg cgacgcgccg acggcgacct ggacgctccc
    27961 ctgcacgttc accgccgacg gtgagctgcg cggtccgtac gtgcagaacc ggctcggcgg
    28021 acgcttcgtc tacctctcct ggctcggcag gcggcccggc gaggaggtct cgcggatgtt
    28081 ccggcgcgcc aagctgatgc tcgacgaggt cgcgccgcgg gtgctcgacg aggcgcggct
    28141 gagcggcgtg ctggtggccc ggctcgctct caccgacgcc cagggcggtc cgctgtgcgg
    28201 gcgggtgccg ctcccggcgg tcgtctggag cgccggcgag ccgtcggacg ccttccccgg
    28261 acgcgccggt cgtcgcccct gacgcgcgcc tcgccgtcgg ccaccgccga gcgcgaccac
    28321 ccgtaccggc cgatccgcga tcagcggccc cggtcctggc cctgggtcgg atccgggagc
    28381 ggagcggtgg gcggtccggg cccccgtcgt ctcccggtgg tgtccctccg tcgggagccc
    28441 caccgggccg gggtcgaacg ccgggcgaac gtcaagctgc cgtcatggag acgccgaccg
    28501 ggggcgccga ggatgtggtg caacggcagg ggcgagaaca ggggccggcc cggcacccgt
    28561 cgcctcctgt cggcagaagg gacagctccg atgcagttcc gcacaaagct cgccgtggtg
    28621 gcgacggccg gcctgctggc ctccgggctc gcgttcgccg gcgaggcgca ggccgccacc
    28681 gggtcgccct ccgcgaacgt gtcgccgaag tgctccaact cctacggtgc cctgcgggcc
    28741 tattacctca gcggctactc cgggccctgc gaggagttct gggcgacctg gcacgacacc
    28801 tccggcatca ccttcagcaa cggtgtcacg gtcaccggcg gtcaggtctg gagcgcggag
    28861 aacgacagct ggcgcaacgc caacatgtac tccggcgcct ggggccaggg gaacctgcac
    28921 atccagtacg ccgggacctc aagcaacaac ctcaagggcc tggggctcct caactcgctg
    28981 agctggacgc ccgattggaa ctgacaccgg cgtcctgaat cggacgcacc ggacgcacag
    29041 accggtcggc ctccgtgacc gcgagccggt cggcgtccgg tgtcgcggac cggtcggcgc
    29101 ggcgtgccac gcgagtggcc gccgtgccgg cctgccaggc ccccgccgcc tccctgccgt
    29161 atccgcatca cgatggagcc gaggtcccgc ccgtgatccc gaagccgcac cgccttggcc
    29221 gcgtcaccgg gccgctcctg ctcgcggccg tactgatggg cgccgcgacc gcctgcgacg
    29281 gcccgccgac ggctcggccc caccccggcg ccgggcaccc cacggtcagc gccgccgaca
    29341 tgcccctgcc cgcccgggtc ccggtgacgt cggtcggcgc gtccccgacc gcctggcaac
    29401 tgcccatgga cgcctaccag tacacaccgg cccagtccgc cgagatccag ggcgccgtct
    29461 actcgctggc caactcctgt atgcgcgacc tgggttactc caccgacctg cccacgcggc
    29521 tgcgcccggg ccccgaccac aacgccttcc gctacggacc ggtgacggac gcccaggcgg
    29581 cccagggtta ccgctggatg ctgcgcaagg ccgcccccaa cggcgccggc gccctgaacc
    29641 cgaccagcga ggagtacggc gcgctgctcg gcaagtcccg ccaggggcgc aacaggcgtc
    29701 ccgtccccac gggtggctgc ctcggctcgg cccgcggcgc cctggacagc cggggaggcc
    29761 gcgtcgcccc cccccgacgt gatccgcgcc atcgccgatg acagctgcgc gctgtcccag
    29821 cgcaccgccc aggttcaggc ggtcttccac gcctggtcgg cctgtatgcg gcgggccggg
    29881 taccgctatc cggacccgac cgcgcccgcc cgcgacaagt cgctcgtcgt acggcgccca
    29941 gcgggaccgg cccaataccc gcggcgggcc cacgcgaggt ggcggtggcc cgcgcggacg
    30001 tcgcctggct tcgtcggtgt agggcgagaa cggttgatgc cgagttcggg caacagatgt
    30061 tgatcaagcg ggtccggcat gttgtcgagt cccgggaacg cctcgtcggt gtgtcggtca
    30121 atcgaagttg atcgaggctg cccgtgggcg agttgtggta ggcagggctg gtgatcagcc
    30181 gactccctct tgaccaacaa cttgagtccc tgcgttcggt gctttcccgt aaccacgtgt
    30241 tgacggaagt actggcgcga actgcggcat tgggcctgcc tgggtggtat gtgacggccg
    30301 ggtgcctgtt ccagacggta tggaacgtgg tcacggagaa gcctccgacc agcggcatcc
    30361 aggactacga cgtcttctac ttcgatgaca gcgatctttc ctgggaggcg gaggacgcag
    30421 tgatccaggc cggccgggag gtctttgccg atctgcccgc agaggtcgag atcaggaacg
    30481 aggcacgggt tcacctctgg tatgaggaca agttcggtgt cccgtgtccg ccgtatgact
    30541 ccgccgaggc agcgatcgac aacttcgccg caacgacatg ctgtctggga gtacgtgtgg
    30601 agatggacgg gcggtggcgt gtctatgcgc cccatgggct gtcggacgtg ttcaaccttg
    30661 tcctccggcc gaacccggtg ttcgccccgc ggtttgtcta tgagaccaag gcggcgcggt
    30721 ggcaggagga gtggcccgag ctgaccgttc tggaatggcc gtccaccgag atcacggtga
    30781 cttcagacct cggccgcgtt cgtgaccgca tcccgggcga cagactcaac aaccatcgct
    30841 gaccacggcc aggacttccg ccgcccggtc cgcctcagcc cagggactgc tgttcggctc
    30901 gggcgcgggt ggtggcgagg cggtaggagt cggtgccggt ctcgatgatg ttgccgccga
    30961 aggtgaggcg gtcgacgatg gcagcgcaaa ggcgggggtc ggtgaaggtc ttggtccatc
    31021 cgccgaagga ctcgttggag gcgatggcga cgctgttctt ctcctcgcgt tcggtcagga
    31081 cttggaagag gagttctgcg ccgcggcggt cgagctccat gtagccgagt tcgtcgatgc
    31141 agaggagatc gacgcggccg tagcgggcga tcgtcttggt cagctgcttc tcgtcggcgg
    31201 cttcgaccag ctcgttgacc agtttcgttg ccaggacgta cttgactcgg aagccggcca
    31261 tcgcggcctc ggtgccgagt gcgatcagaa ggtgtgattt gccggtgccc gagtctccga
    31321 tgaggcagag gggcagtccc ttcttgatcc attcgcactt ggcgagggtg tggatcatgg
    31381 ctgcgtcgat gttggggttg gcgtcgaagt cgaacttgcg gagcgacttg tcgcggggga
    31441 atccggcggc cttgatgcgg cgctcggaac ggcggcgggc ccggtcgtcg cattcggcca
    31501 ggaggagctc ggcgaggaag ccgaggtagg acatctgctc gcggctcgcg gtctcggcaa
    31561 ggtcggggaa ctgggagcgg atcgtgggca gccggagcat gcggcatgcc tggtcgaccg
    31621 cggtggtggc ggcctgctcg gtgagtcctc gctgacgggg aagggacacg gcgttctcct
    31681 ctatgaaggg gtggggcggt cggttcggcg gagccgcagg agctggtcgt agtgggcgac
    31741 ggagggcagg ggccgtttgt ctagcggcag atgagccctg acagtcgcgg gcagcgggag
    31801 cgtcctggtc tggccgacgg cggttgtcga ctgctggggc tcatcgggcc tggtgtcggc
    31861 gtcggctgcc ttgcgggctt ccaaagcgac ggcatcagcg gtgagggcgc cggtcttcag
    31921 ggccgcggcg aggccggtga cgaggtgttc gtggggaagg tggcggctga gcaggaggac
    31981 ttcaatcagg gcccgggtgc cgtcgcgttc gccgtgggct ttgacggcgg cttcccacca
    32041 ggcgtcgtgg atgggggtga accggccggc ggcccgggct tggtcgaggg cggtggcgcc
    32101 gggcagggca ccgggcttgc ggatcagcgc ctccaggtag tgatcgaggt cgaggcggga
    32161 gccgtcgcgg gcgatgagcc gttcgtgccg ggcgacttcc tcgcggccgt cgtagacgac
    32221 gagctcggag gcgtggagca tgacgcggac ggtgcggccg atcagccgca cgggtaccga
    32281 gtagcggttc atccggacac agatctggcc gtagcggtcg acccgcgggg tggagagccg
    32341 gcccgtctcg aacggctcct ccggcagcgg tgccagcagc ggctgctcga cggcgaagta
    32401 ctcaccgatc gtgtgcgggc gggagcggat gcggcgggcg tcgtcctcct ggtcccaccg
    32461 gtcgatcatc tcgttgagct cggcgagcgt gtccacttcg gggacgggga ccaggtggtt
    32521 gcggcggaac cagccgatct ggccctcgac gccgcccttc tcgtgggcgc cgcgcaggcc
    32581 gggctggcag tagagggcgt cgatgccgta gtgggaccgg aaggcggtcc agcgttcggc
    32641 ttccacccgg cggcgtgaga ggcccagcac ctgggcgacg gcggctctaa ggttgtcgta
    32701 gcggaccttc ccggtcggcg ctccgcccag cacgttgaga gcgtggacgt ggccctcgaa
    32761 gaacgcctcc tgcccggccg aggcgaagat gcggtggacg gccttgcccg agtacgacat
    32821 tcggaacgcg aacaggtagc aggtcaccag ctcgccggcc agcttcaccg cgacgtcccc
    32881 gaagtcgact tcggcctcgg caccaggcct gtgggtctga gggacgaacg cgtcgaccac
    32941 acccttgcca gcctgcaggc ggatctcctc acggcggcca gcgacgtagc cgcggaccat
    33001 ctgataggag atgccgacgg cgttgtgctc gtccagcaac cggtcataga tccgcttgac
    33061 cgtgtgccgc tgtttccgcg gagcggtcag gtccgccttc aggatggcgt cgatcaccgg
    33121 cttgtaggga tccagccgcg tcgctcgcgg cctcatcttc ttccgcggct ccggcagagc
    33181 cgagatcaag gccctctgca cggtctcgta gccgacgccg tacttccgca tgagcgcgcg
    33241 cgtcgacatg ccggtcctgg cgtcacggcg gatcgccgcg tacagatcga ccttggactt
    33301 cggcagcacc ccgaccccct cgtcgtgcag agcacaacca gggtcccgaa gcaagcaccg
    33361 aggtgttctc gaaactcagc gacatcactc tcacgtggaa cgaggcgttc gcgccgctga
    33421 gcaacagacg ttcgcgaaac tcacctacaa agccacgcct gcaaacgcca ggtcgggctc
    33481 ctgtcggtct ggtactccgt cgaacggacc atgcagtccg aggcggccgc ccgccatgcc
    33541 gtcgaactcg ctcccgtccc agccgccatc gcccggaccg tacgcaacgc caccgccgtc
    33601 ctggccgccg gtggccaccc cggctgaacc gggcccgcac gctgaacaga ggacccgcgc
    33661 accacgcttc ccctccgcct gagcggccgc gagcccggtg cggacttgcc ctcccccagg
    33721 acaagcagca gttgaacccg taccggctgt tgaccgagaa tggttcgact gacttgtgcc
    33781 gtttcgacgg ctaaccg
//
