LOCUS       NZ_CP071875            29839 bp    DNA     circular CON 27-MAR-2024
DEFINITION  Paenibacillus polymyxa strain SF05 chromosome, complete genome.
ACCESSION   NZ_CP071875
VERSION     NZ_CP071875.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5459135)
  AUTHORS   Chen,B., Zhao,F. and Han,H.
  TITLE     The complete genome sequence of Paenibacillus polymyxa SF05, an
            antagonistic strain isolated from maize sheath
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5459135)
  AUTHORS   Chen,B., Zhao,F. and Han,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAR-2021) Institute of Maize and Featured Dryland
            Crops, Zhejiang Academy of Agricultural Sciences, Tangxi Village,
            Chengdong Sub-district, Dongyang, Jinhua, Zhejiang 322100, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. v3.6.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400.0x
            Sequencing Technology             :: Nanopore; Illumina PE150
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028751565.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 02:05:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,074
            CDSs (total)                      :: 4,919
            Genes (coding)                    :: 4,764
            CDSs (with protein)               :: 4,764
            Genes (RNA)                       :: 155
            rRNAs                             :: 15, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 15, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 108
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 155
            CDSs (without protein)            :: 155
            Pseudo Genes (ambiguous residues) :: 0 of 155
            Pseudo Genes (frameshifted)       :: 76 of 155
            Pseudo Genes (incomplete)         :: 112 of 155
            Pseudo Genes (internal stop)      :: 26 of 155
            Pseudo Genes (multiple problems)  :: 50 of 155
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:54:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5308085
            Orig. end                         :: 5337924
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP071875.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..29839
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="18"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     cand_cluster    1..29839
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..29839
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:24839]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..24839
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     misc_feature    59..72
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.45"
                     /tool="antismash"
     gene            171..749
                     /locus_tag="J4I02_RS24645"
                     /old_locus_tag="J4I02_24350"
     CDS             171..749
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014278856.1"
                     /locus_tag="J4I02_RS24645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24350"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_274483240.1"
                     /transl_table=11
                     /translation="MEKSSDVLTKEQILIATEDTLRRFGVAKTSVTDVAKVLGVSHGTI
                     YRHFKSKAELLEGVTEKWLNEKIIAPLTEVCQNSSILGTPHLKRYIQTLVELKQYYARD
                     DEEMFEMYTRVTEQAADLIDQHIAHIVDQLADIIARGDIISDQPTQLARTLFYATARFH
                     HPAHAYEWKNPLINQEFSDVWMLLEKGIT"
     gene            780..1520
                     /locus_tag="J4I02_RS24650"
                     /old_locus_tag="J4I02_24355"
     CDS             780..1520
                     /NRPS_PKS="Domain: PKS_KR (7-120). E-value: 4.9e-13. Score:
                     41.3. Matches aSDomain:
                     nrpspksdomains_J4I02_RS24650_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426073.1"
                     /locus_tag="J4I02_RS24650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24355"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_274483242.1"
                     /sec_met_domain="adh_short (E-value: 4.2e-34, bitscore:
                     116.2, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 5.2e-39, bitscore:
                     132.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHLDGKTAIITGSSRGIGRAIAEQLADLGANVVINYASSPDKAQ
                     KVVERIIQKGGKAIALHADLGKMSDIEALFTNTIAEFGKVDILVNNAGMMITQPLAEVT
                     EADFDQQFALNVKGTFFACQQAMKYMENYGRIVNLSTSVIGQMFPAYSVYAGTKGAVEQ
                     FTRQLAKEFGNKQITINAVAPGPVNTELFQAGKTEQQIEAMKKMNAMGRLGEPEDIADV
                     IEFLVSAKSQWVTGQTIRVNGGFI"
     aSDomain        801..1139
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J4I02_RS24650_PKS_KR.1"
                     /evalue="4.90E-13"
                     /label="J4I02_RS24650_PKS_KR.1"
                     /locus_tag="J4I02_RS24650"
                     /protein_end="120"
                     /protein_start="7"
                     /score="41.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TAIITGSSRGIGRAIAEQLADLGANVVINYASSPDKAQKVVERII
                     QKGGKAIALHADLGKMSDIEALFTNTIAEFGKVDILVNNAGMMITQPLAEVTEADFDQQ
                     FALNVKGTF"
     CDS_motif       807..872
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_J4I02_RS24650_0001"
                     /evalue="3.60E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="J4I02_RS24650"
                     /protein_end="31"
                     /protein_start="9"
                     /score="16.4"
                     /tool="antismash"
                     /translation="IITGSSRGIGRAIAEQLADLGA"
     gene            1556..2092
                     /locus_tag="J4I02_RS24655"
                     /old_locus_tag="J4I02_24360"
     CDS             1556..2092
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373777.1"
                     /locus_tag="J4I02_RS24655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24360"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_250240939.1"
                     /transl_table=11
                     /translation="MMLHKGETLFRQGESGPLYHLKSGLLKIVRVHEDGSQILVNVIVP
                     DEIIPHHSLISPNPYYGTAVALVTSEVGVLSQKEWYQALEQDPTQCRAIALQLQDKLRM
                     MQQRIDQLTEVSPAEKLRKLQRWFHSYIAPATLTDVLTQEEIGQFIGLRRETINRLLRA
                     SSAPSAKDDDDNASR"
     gene            complement(2025..2546)
                     /locus_tag="J4I02_RS24660"
                     /old_locus_tag="J4I02_24365"
     CDS             complement(2025..2546)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312652.1"
                     /locus_tag="J4I02_RS24660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24365"
                     /product="DinB family protein"
                     /protein_id="WP_274483243.1"
                     /transl_table=11
                     /translation="MNTTETLQRFEETAQHYLLEVDSFSLEQLQYTPQEDQWSLGQMYL
                     HLVNSALYMHLKNIDLCLQPNGETGVKTEAGTAIFNLGGFPPIRIQVPPSPQYTPPQPT
                     SKEEIVEGLNVVIRKMREIEPTVGRSTGPSTVSHPRFGALNAGEWFSLIEMHYRHHLLQ
                     KERLKHAIAD"
     gene            complement(2614..3558)
                     /locus_tag="J4I02_RS24665"
                     /old_locus_tag="J4I02_24370"
     CDS             complement(2614..3558)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426071.1"
                     /locus_tag="J4I02_RS24665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24370"
                     /product="YafY family protein"
                     /protein_id="WP_274483244.1"
                     /transl_table=11
                     /translation="MNKTDRLLAILLELQRKDILRAEDLAAIFETSVRTIYRDIQALSE
                     SGVPIVGAPGIGYSLMEGYFLPPLSFTAEEAVALLIGTDFVEQKFDTDYGIKAQTSRRK
                     IEAILPESVRREVSRVRTTIRLLAVGEGANHSEKTCLEKLRLAVLEKRKVRFGYSKRMP
                     EADGNRQSVRVVAPYGLVLLRGSWVLIGQCELRQQLRHFRLSRMDELIVLEDRFQLPVD
                     FHLQDYKQTDDRHVTVRILARLDIADKVKEANNFYMEAIEERADGLHILFRVRQPEELL
                     QWILGWGADMVVLEPESLRERIRAEVEKMLKCY"
     gene            complement(3668..4024)
                     /locus_tag="J4I02_RS24670"
                     /old_locus_tag="J4I02_24375"
     CDS             complement(3668..4024)
                     /GO_function="GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822573.1"
                     /locus_tag="J4I02_RS24670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24375"
                     /product="nucleotide excision repair endonuclease"
                     /protein_id="WP_013312654.1"
                     /transl_table=11
                     /translation="MINITIPTPDITITKQVNPELSHIYGFTDFHLIPRDKAGIFMFYN
                     AQEELLFVGKARKLRPRIKKHFEDNVSPIKDKRNEVAIIEVCIVEDAVEREIYETYIIN
                     TQKAKYNVEKVFFK"
     misc_feature    4051..4066
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.06"
                     /tool="antismash"
     gene            complement(4244..4984)
                     /locus_tag="J4I02_RS24675"
                     /old_locus_tag="J4I02_24380"
     CDS             complement(4244..4984)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014278862.1"
                     /locus_tag="J4I02_RS24675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24380"
                     /product="YheC/YheD family protein"
                     /protein_id="WP_274483245.1"
                     /transl_table=11
                     /translation="MPSAAKDKWYKYLLLRRYASLKSYVPETKLLDRYHFSKLLSKYVH
                     VIVKPVWGSRGQGIFQVSWLGHHKYLVHYENKKVLVRGRTNTYYYIRRKIGNASYMVQR
                     RITRPTINKRPFDMRVIIQRRINSSVWVVTGKVIKVAGKGYIVSNNTRSKGTLHHFKSG
                     IRQSSIRHLSASTLESHINRVSIRSAKRLSTFFPGHRIYGLDIGIDRKGRIGIIEANLF
                     PARSHFRKLRDKTMYHRITDYKNG"
     gene            complement(5001..6113)
                     /locus_tag="J4I02_RS24680"
                     /old_locus_tag="J4I02_24385"
     CDS             complement(5001..6113)
                     /EC_number="2.6.1.37"
                     /GO_function="GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_5 (33-312). E-value: 4.3e-33.
                     Score: 106.6. Matches aSDomain:
                     nrpspksdomains_J4I02_RS24680_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014278863.1"
                     /locus_tag="J4I02_RS24680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24385"
                     /product="2-aminoethylphosphonate aminotransferase"
                     /protein_id="WP_274483246.1"
                     /sec_met_domain="Aminotran_5 (E-value: 1.4e-28, bitscore:
                     98.1, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.6e-06, bitscore:
                     23.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSSVKKNILLTPGPATTTESVKWSQVVPDICPREAEFGQIMEYI
                     STELTRLVANPDHYATVLFGGSGTAAVESIISSVPNHDAVIIVSNGAYGKRMCEIAKVY
                     GVDYLEFKSPPDSAIDLAELERYIQSSEHTVSHLAVVHHETTTGLLNKVKDIGELCKRY
                     QIDMIVDAMSSFAAIPIQLKEMNIAYLAASSNKNLQGMAGVSFVIARKSKLENLKDQKP
                     RSFYLNLYAQYNYFVEHGQMRFTPPVQTLYALRQAIEELKQEGVDKRYERYATSWKTLI
                     NGLTRLGLTYIIPEEHHSKIITSILEPHCAGYDFQSMHDYFYSKGIMIYPGKLEKLNTF
                     RIANIGDITYKEMELFLELLESYLSSIKCG"
     aSDomain        complement(5178..6014)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J4I02_RS24680_Aminotran_5.1"
                     /evalue="4.30E-33"
                     /label="J4I02_RS24680_Aminotran_5.1"
                     /locus_tag="J4I02_RS24680"
                     /protein_end="312"
                     /protein_start="33"
                     /score="106.6"
                     /tool="antismash"
                     /translation="REAEFGQIMEYISTELTRLVANPDHYATVLFGGSGTAAVESIISS
                     VPNHDAVIIVSNGAYGKRMCEIAKVYGVDYLEFKSPPDSAIDLAELERYIQSSEHTVSH
                     LAVVHHETTTGLLNKVKDIGELCKRYQIDMIVDAMSSFAAIPIQLKEMNIAYLAASSNK
                     NLQGMAGVSFVIARKSKLENLKDQKPRSFYLNLYAQYNYFVEHGQMRFTPPVQTLYALR
                     QAIEELKQEGVDKRYERYATSWKTLINGLTRLGLTYIIPEEHHSKIITSILEPHCAG"
     gene            complement(6110..7270)
                     /gene="aepY"
                     /locus_tag="J4I02_RS24685"
                     /old_locus_tag="J4I02_24390"
     CDS             complement(6110..7270)
                     /EC_number="4.1.1.82"
                     /GO_function="GO:0033980 - phosphonopyruvate decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aepY"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312657.1"
                     /locus_tag="J4I02_RS24685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24390"
                     /product="phosphonopyruvate decarboxylase"
                     /protein_id="WP_274483247.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.5e-08, bitscore:
                     32.6, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.3e-16, bitscore:
                     57.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTKLLGEELKKLGFTFFSGVPCSFLKSLINYAINECDYVAAANE
                     GDAVAIASGAYIGGKKAVVLMQNSGLTNAISPLTSLNYPFHIPLLGFVSLRGEPGIPDE
                     PQHELMGRITTQMLDVMGVEWQYLSKNLEEAKTQLIQADEQIARHRSFFFVVKKGTFDK
                     KLLQKLETSIHLNQIRQHGHAGHQMPTRYDALSAINSMKDDDTIQLATTGKTGRELYEI
                     EDAANNLYMVGSMGCIGSLGLGLALSQPSKDIVVIDGDGSLLMRMGSLATNGYYHPANM
                     VHILLDNNAHESTGGQSTVSHNVDFIDIAASCGYTKSIYVHSLEELKACLQEWKVDKGL
                     TFLYLKISKHSKDQLARPHMKPHEVKERLQRFIHNSPLKGKGVGGS"
     gene            complement(7270..8169)
                     /gene="aepX"
                     /locus_tag="J4I02_RS24690"
                     /old_locus_tag="J4I02_24395"
     CDS             complement(7270..8169)
                     /EC_number="5.4.2.9"
                     /GO_function="GO:0050188 - phosphoenolpyruvate mutase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019634 - organic phosphonate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="aepX"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) phosphonates-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014278865.1"
                     /locus_tag="J4I02_RS24690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24395"
                     /product="phosphoenolpyruvate mutase"
                     /protein_id="WP_274483248.1"
                     /sec_met_domain="phosphonates-like (E-value: 2.9e-137,
                     bitscore: 454.4, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 2.1e-131, bitscore:
                     435.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1e-67, bitscore:
                     226.3, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTKQLRELINSRKLEFIMEAHNGLSAKIVEETGFKGIWASGLS
                     ISAAMGVRDSNEASWTQVLDVLEFMSDATSIPILLDGDTGYGNFNNARRLVRKLEQRHI
                     AGVCIEDKRFPKTNSFINGQGQTLADIEEFSGKIKAMKDTQTDEDFTVVARVEAFIAGK
                     GLKAALQRAEAYRKAGADSIFIHSKRSDAAEIEAFMKEWAGRLPVVIVPTKYYTTPTVR
                     FQEMGISLVIWANHNLRASIQAMKQLSDRIYRDESLVHIEKSVATLEEVFRLQGVEELQ
                     AAERKYLPSSEPDSGEHV"
     gene            complement(8211..8939)
                     /locus_tag="J4I02_RS24695"
                     /old_locus_tag="J4I02_24400"
     CDS             complement(8211..8939)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014278866.1"
                     /locus_tag="J4I02_RS24695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24400"
                     /product="YheC/YheD family protein"
                     /protein_id="WP_274483249.1"
                     /transl_table=11
                     /translation="MPIGKMKKHKEMLQHPVLRPHLPETHWFTDSRTSRMLNTYSSVFI
                     KPNFGSGGSGIIRVKRLKKGYEVRRGSSRRIVGSRFVLKAIKSYQKSRHMYLVQKGLRL
                     AKYHGSIFDTRIYLQKPGRKWVISGAAARVAAPHKYVTNYLKGGHAVSLHRALFSLFKH
                     NRTKADAYYHRISKLSVIIAKTVNKRHPVRELGVDIAIDKKGRIWIIEANSHPGHMLFT
                     QLPDPTMIKTIMRNKRLIRK"
     misc_feature    complement(8982..8995)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.88"
                     /tool="antismash"
     gene            complement(9241..9585)
                     /locus_tag="J4I02_RS24700"
                     /old_locus_tag="J4I02_24405"
     CDS             complement(9241..9585)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J4I02_RS24700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="J4I02_24405"
                     /product="hypothetical protein"
                     /protein_id="WP_274483250.1"
                     /transl_table=11
                     /translation="MKTKKTVWIPAIIAVTVAALLVIYYYYTPSVSGGGLGLRPPGGEV
                     SNVPGHMGGRPGEKGGGGNGELFKTLGTISVFLGAATWGSCLDTGKKCGKNDEACPGGA
                     IIRQAAAIWP"
     gene            9852..10475
                     /locus_tag="J4I02_RS24705"
                     /old_locus_tag="J4I02_24410"
     CDS             9852..10475
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426070.1"
                     /locus_tag="J4I02_RS24705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24410"
                     /product="acetate uptake transporter"
                     /protein_id="WP_274483251.1"
                     /transl_table=11
                     /translation="MQNESHANVKIITADPSAIGLFGLAIVTLVASSQKLGLTEGLSFI
                     IPWAIFLGAFAQLFACIQDAKHNNTFGMTAFGAYAFFWLAVASSWMIKMGVFGSELASA
                     VDGKQLGFAFAGYLIFTLFMTIGAMETHKVLFFIFVLIDFLFLGLSFDAFGVAPEVFHT
                     IAAYAEMGIGLLSLYGTGAAVLNAHFGRTFLPVGRPFGIFKPRP"
     gene            <10700..10936
                     /locus_tag="J4I02_RS24710"
                     /old_locus_tag="J4I02_24415"
                     /pseudo=""
     CDS             <10700..10936
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010899996.1"
                     /locus_tag="J4I02_RS24710"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24415"
                     /product="(2Fe-2S)-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="DEGAVIRVNGKRAGAYRDPQGALHLVDTTCTHMGCEVEWNEAERT
                     WDCPCHGSRFSYQGEVIEGPAKKSLGKVENSSE"
     gene            11078..11287
                     /locus_tag="J4I02_RS24715"
                     /old_locus_tag="J4I02_24420"
     CDS             11078..11287
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822559.1"
                     /locus_tag="J4I02_RS24715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24420"
                     /product="hypothetical protein"
                     /protein_id="WP_274483252.1"
                     /transl_table=11
                     /translation="MVYGLHETLEVHELSAFKTVCLTKSKTIQALISDPTLKAILQQDV
                     DLSTRQLQELGTLLDQAISQEVKS"
     gene            11284..11583
                     /locus_tag="J4I02_RS24720"
                     /old_locus_tag="J4I02_24425"
     CDS             11284..11583
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226009.1"
                     /locus_tag="J4I02_RS24720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24425"
                     /product="spore coat protein"
                     /protein_id="WP_274483253.1"
                     /transl_table=11
                     /translation="MNTLLEHLTGLNTLTDQVIAADFLNAAKSGVRNYAMAVTEAGTPE
                     IKAILTKQLDEAIDTHEQISTYMIERGWYHPWNVKEQLSMDLQNINTALQAPVL"
     gene            complement(11731..12717)
                     /locus_tag="J4I02_RS24725"
                     /old_locus_tag="J4I02_24430"
     CDS             complement(11731..12717)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007433115.1"
                     /locus_tag="J4I02_RS24725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24430"
                     /product="aldo/keto reductase"
                     /protein_id="WP_274483254.1"
                     /transl_table=11
                     /translation="MKKKQLGNSDLQVSALGLGCMGMSEYYGELNDQESINTLHRALEL
                     GINFWDTADVYGVGKNEKLISQVLRSRRDEVILATKFSIMRGEDGGFLGVSGRPEYVKE
                     ACDRSLQRLGVDVIDLYYQHRVDPNVPIEETVGAMSDLVQAGKVRYLGLSEASPALIRR
                     AHKVHPITALQTEYSLWSREAEDEVIPTCRELGIEFVAYSPLGRGFLSGQIQKFDDFAE
                     DDFRRTVPRFQPENFQKNLDLVKHIKDLAAQKGVKPSQLALAWLLAQEGIVPIPGTKRV
                     TYLEENAGAVDVVLSAEEMETINAIIPKGMAAGLRYPAERMPNWQAE"
     misc_feature    12829..12844
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.57"
                     /tool="antismash"
     gene            12984..13679
                     /locus_tag="J4I02_RS24730"
                     /old_locus_tag="J4I02_24435"
     CDS             12984..13679
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312664.1"
                     /locus_tag="J4I02_RS24730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24435"
                     /product="response regulator transcription factor"
                     /protein_id="WP_274483255.1"
                     /transl_table=11
                     /translation="MFKILLIEDDETLFHEMKDRLTQWNYDVYGIQDFNKVIQEFTTIK
                     PDLVVIDIQLPKFDGFHWCRMIRSHSNVPILFLSSRDHPTDMVMSMQLGADDFIQKPFH
                     FDVLIAKLQATLRRVYNYNTEPVSLKTWRGATVDYEKNVVANEAGSIELTKNEIFILKL
                     LIEQKNKIVAREELIKSLWDDERFVSDNTLTVNLNRLRKKLDELDLSRFIETKVGQGYM
                     ATEEAPTND"
     gene            13672..14676
                     /locus_tag="J4I02_RS24735"
                     /old_locus_tag="J4I02_24440"
     CDS             13672..14676
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373799.1"
                     /locus_tag="J4I02_RS24735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24440"
                     /product="sensor histidine kinase"
                     /protein_id="WP_274483256.1"
                     /transl_table=11
                     /translation="MIKKYLIERRSWILLFVCQQFLILFIAYVDAAIPLMPILYIVFLS
                     MMIFLVFLIIRYLKETKFYTTLEEWESPLELTGIGEPESPFEQIIEQKITDQTEQLQQV
                     ISQNQLTLEHEKDELLSWIHEVKTPLTTMHLMIERLDDKPLKAQLTYEWLRIHLLLDQQ
                     LHHKRISFIENDLYIEQVNLKSLVFNEIKALQSWCIQKGIGFDIQLVHMEVLSDAKWLA
                     FIIRQLLTNAIKYSDASDIIIHSYEQRDRIQLEVQDFGRGIDPKDIPRIFEKGFTSTTQ
                     HSDHTSTGMGLYLTKKAAQSLLIHIDVHSKPNVGTTFTLIFPKRNDFVSMVSM"
     gene            14779..15540
                     /locus_tag="J4I02_RS24740"
                     /old_locus_tag="J4I02_24445"
     CDS             14779..15540
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390916.1"
                     /locus_tag="J4I02_RS24740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24445"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_274483257.1"
                     /transl_table=11
                     /translation="MNILEAHKIHKSYGNKLNMQEVLKGIDILIEEGEFVSIMGASGSG
                     KTTLLNVLSSIDKVSQGSIKINDIEMTKMKEKQLAEFRKKHLGFIFQEYNLLDTLTVKE
                     NILLPLSITKTPKKEANQKFQEVATELGIYELKDKYPNEISGGQKQRTSAARAFIHEPS
                     IIFADEPTGALDSKSASDLLNKLGQLNQKRKATIIMVTHDPVAASHCSRVIFIKDGQLY
                     TQLHKGEQERQSFFQDIMKTQGVLGGVQYEH"
     gene            15530..17470
                     /locus_tag="J4I02_RS24745"
                     /old_locus_tag="J4I02_24450"
     CDS             15530..17470
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1243: ABC
                     transporter, permease component"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426059.1"
                     /locus_tag="J4I02_RS24745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24450"
                     /product="ABC transporter permease"
                     /protein_id="WP_274483258.1"
                     /transl_table=11
                     /translation="MNINLLILKNLKKNLKNYYLYVFALIFSVALYFAFVTLQYDPSMD
                     EVKGSVKGAASIRAASILLVAIVCIFLMYANNIFIKRRSKEIGLFQLIGMTKSKIFRIL
                     SAENLILYFSSLFIGIGVGFSFSKLVIMILFKTTGVEAIATLYFSNQALTQTLIVFVVI
                     YLLIMLMNYSFIKRQSILSLFRVTSTTEGKIKKISIFEMIIGIIGISLIALGYYVSSKL
                     FGGDFTSINELFMAMVFILGTVIIGTLLFYKGSIRFISNIIRKSKGGYLNINEVLSLSS
                     IMFRMKSNALLLTIITTVSALAIGLLSLSYIAYYSADQAAEDNVPSHFAMTNVPDAEKF
                     KALLHEHDIKYREKKIEVIQVSVKTAQIMETPMEQLNDGTDSMTLPVVSDQSVEGTDVN
                     PGQTVLTGYNDMLQKFMSLKDFGPLDLKGKTEVIPQRYVGLKKDYVIPYYFTVGGVPTV
                     IVDETIFERLKKDVNPKIQKKSSLYIGIDMLNEAQIEEADRLFAAANFNDQQSSRLEMS
                     SNQKRSMGVIMFVVGFLGLTFLITSGCILYFKQMDESEDEKANYTVLRKLGFTQSDLLR
                     GIKIKQLFNFGIPLVIGLSHSYFAVQSGWFLFGTEIWRPMIIVMVLYTALYSIFGILSI
                     LYYKKVIKSAL"
     gene            17626..18054
                     /locus_tag="J4I02_RS24750"
                     /old_locus_tag="J4I02_24455"
     CDS             17626..18054
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373802.1"
                     /locus_tag="J4I02_RS24750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24455"
                     /product="hypothetical protein"
                     /protein_id="WP_274483259.1"
                     /transl_table=11
                     /translation="MANIILGSFIGAAIFMGIVFFLIGWPEFKKSPKLTKKAKKDIAYI
                     MSTLLTLVVFMVIVCWNIRASGDLMLAGPLTPQMKFHWGQKVLMLGLLEGLWAVITLKW
                     LLPIFFDPLDLSKKQILVLVSGIVFSVVSGIYAMLEAS"
     gene            complement(18061..19035)
                     /locus_tag="J4I02_RS24755"
                     /old_locus_tag="J4I02_24460"
     CDS             complement(18061..19035)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426058.1"
                     /locus_tag="J4I02_RS24755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24460"
                     /product="aldo/keto reductase family protein"
                     /protein_id="WP_274483260.1"
                     /transl_table=11
                     /translation="MKYRNVGNSGLKISEIGLGSWLTYGTAAEQEVAHTCIAKAFELGI
                     NFFDTANAYNRGEGEKAMGAALKSYRRDSYVLSTKVYFPMDSGPNDRGLSRKHIMEQCE
                     ASLKRLGTDYIDMYFCHRYDPDTPLEETLRALDDLQAQGKILYAAVSEWSAAQLMDAHG
                     IGKRLNLRPLIANQPIYNMFERYIEHEVLPVSGKVGIGQIVFSPLAQGILTGKYKPGQP
                     LPTGSRGADASVNNVISSYMNDTVLNCVQELDKLAKDLGVTLSQLALAWILREPGISAA
                     LIGATKPAQIEENVKAVDVTLQPETCVEIERILKQAEGFEPLR"
     misc_feature    19066..19082
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.99"
                     /tool="antismash"
     misc_feature    19073..19088
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.71"
                     /tool="antismash"
     gene            complement(19197..20159)
                     /locus_tag="J4I02_RS24760"
                     /old_locus_tag="J4I02_24465"
     CDS             complement(19197..20159)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019689021.1"
                     /locus_tag="J4I02_RS24760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24465"
                     /product="radical SAM protein"
                     /protein_id="WP_274483261.1"
                     /sec_met_domain="PF04055 (E-value: 1.9e-16, bitscore: 59.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.7e-06, bitscore: 26.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 9.7e-07, bitscore: 26.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIENKYKALELEKPGIYELEGLEVGVTSNCNFKCDYCCAYQRND
                     GQCISSKEVIDIIDDIPTLKRVRLSGGEVTLKYEDCLDIVAHCSNKGIATQLNTNASLL
                     SPERIEKLRDAGLSNIHISFNFTEADKYAAYYHVHPRMYEKIVQNIRLCTEAKLETVLE
                     TLLFAETQNNMPAISEMVYELGVRIHEIQNSIVMDHTNWNAISTKEALVRSVHDLIAHK
                     KDDTVLYFTCMDRFAEALGFREQPGVYFSNCVDGKKQLHLHGNGDILICELCHPVVIGN
                     IYNGTSLKDIYKNKPKQLQEFLDKLPCPAYDALFPVGSK"
     gene            complement(20368..21582)
                     /locus_tag="J4I02_RS24765"
                     /old_locus_tag="J4I02_24470"
     CDS             complement(20368..21582)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426056.1"
                     /locus_tag="J4I02_RS24765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24470"
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="WP_274483262.1"
                     /transl_table=11
                     /translation="MFIGENLTNLRIMHGYSRKQLSEMLGVTEQAVWQYENAYTSPKMQ
                     IVNELKRIFNVKSKYFYTKDMLARNMTPANVNVMNIAYRSKVLNVISKTQAEAKHVEYL
                     DAFINYITARVSLPTLKIISLRDEVIEYLNHSDDDRSTQIDKVAHLARKRLGLAQDTND
                     DLMFLVEKSGVFAFEKAMGDEIDAYSLWTQNDRPYIILGNMKRSAVRRNFDVAHELGHL
                     LLHYRLEFANLDRKEHKIIENEANMFAGAFLLPEDEFTLDMKNVVHITNPDNYLDLKKK
                     WKTSLQVLGYRAAHLGNLKPKDHRNFYAALHRKGYLKIEPLDELITIQKPTKIKTIIDL
                     VSKKGLVNIHQMVENDWKTEVSFFYRMTGIVPDFFNKYLAASLDFGLQNVTDISKRFSD
                     VAKQV"
     gene            complement(21621..22364)
                     /locus_tag="J4I02_RS24770"
                     /old_locus_tag="J4I02_24475"
     CDS             complement(21621..22364)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822541.1"
                     /locus_tag="J4I02_RS24770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24475"
                     /product="DUF5986 family protein"
                     /protein_id="WP_274483263.1"
                     /transl_table=11
                     /translation="MDKFKFNSEHNKMIVDAIVDGYRDYIEHRKDRKAKMKISSAFAWT
                     KGNFIESKIAEECVDYGFTYKKSKAGLTWDYLQFIHGDSKILFLIKNAAYFNEKCFSQA
                     KLPSNYGGKGPRRTYLHELSKINKDLLFSPTQQSSKIRGVPEQLSFLILESQVKDELES
                     FKSSYNEFHILTYALDEAYQISEIMHYLPNPEDNIAYLIEDLSSLISGADLTEEDREVV
                     APEMSEDIMDPAAFDIGILEEEQHN"
     misc_feature    complement(22462..22480)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.86"
                     /tool="antismash"
     gene            22720..23196
                     /locus_tag="J4I02_RS24775"
                     /old_locus_tag="J4I02_24480"
     CDS             22720..23196
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014278884.1"
                     /locus_tag="J4I02_RS24775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24480"
                     /product="DsrE/DsrF/DrsH-like family protein"
                     /protein_id="WP_274483264.1"
                     /transl_table=11
                     /translation="MDKRMNLLMFSGDYDKAMAGLILANTARELDVDVTMFFAFWGLSL
                     VRDPEKMTLEDKTIYEKLMDLMTPKGPESMPLSHMNFSGLGKLMLTEMLEDNEAPKLIH
                     FLKGARKKNVKFYACKLSVEIMGFKPEEFIPELEIIEAKTYLKDALESDMQLFI"
     gene            23331..24839
                     /locus_tag="J4I02_RS24780"
                     /old_locus_tag="J4I02_24485"
     CDS             23331..24839
                     /NRPS_PKS="Domain: Aminotran_5 (44-455). E-value: 1.5e-48.
                     Score: 157.5. Matches aSDomain:
                     nrpspksdomains_J4I02_RS24780_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019689023.1"
                     /locus_tag="J4I02_RS24780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24485"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_274483266.1"
                     /sec_met_domain="Aminotran_5 (E-value: 1.9e-45, bitscore:
                     153.6, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLMARIGSSNCRYQPSNEAYFQRYRESTIGYHQTFESPYGQKKLI
                     YADWAASGRLYGPIESKIAHELGPFVANTHTESNLTGTLMTQAYEEAKQIIKSHVHANE
                     HDIILFAGSGMTGAVNKLQRLLGLKIHEKLKHHYPIAEKERPVIFVTHMEHHSNHISWA
                     ETIGDVVCLPLGPDGIVDPTQLERLLLQFRHRPIKIGAFTACSNVTGFEPPIYQLSRKM
                     HEHGGVCFVDFSASAPYAAINMHPAEPLERLDAIVFSPHKFLGGPGTSGVLIMDSRLCL
                     NCAPDQPGGGTVSWTNPWGGYEYKNNTEAREDGGTPAFLQATRTALCIRLKEQMGQKRL
                     LERKKELTSLLLKSLSTIPGLHILGGSSQERMGIVSFVVSHIHYNLIVKLLNDRFGIQV
                     RGGCSCAGPYGHYLLGIDPQTSKQMTDLIHAGDLSRKPGWVRLSLHPMMTNQEVSYIAS
                     SIRAIVENIMTWQKDYTYQPESNEWRAMHEHNKIDISKWFNFSD"
     aSDomain        23463..24695
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_J4I02_RS24780_Aminotran_5.1"
                     /evalue="1.50E-48"
                     /label="J4I02_RS24780_Aminotran_5.1"
                     /locus_tag="J4I02_RS24780"
                     /protein_end="455"
                     /protein_start="44"
                     /score="157.5"
                     /tool="antismash"
                     /translation="IYADWAASGRLYGPIESKIAHELGPFVANTHTESNLTGTLMTQAY
                     EEAKQIIKSHVHANEHDIILFAGSGMTGAVNKLQRLLGLKIHEKLKHHYPIAEKERPVI
                     FVTHMEHHSNHISWAETIGDVVCLPLGPDGIVDPTQLERLLLQFRHRPIKIGAFTACSN
                     VTGFEPPIYQLSRKMHEHGGVCFVDFSASAPYAAINMHPAEPLERLDAIVFSPHKFLGG
                     PGTSGVLIMDSRLCLNCAPDQPGGGTVSWTNPWGGYEYKNNTEAREDGGTPAFLQATRT
                     ALCIRLKEQMGQKRLLERKKELTSLLLKSLSTIPGLHILGGSSQERMGIVSFVVSHIHY
                     NLIVKLLNDRFGIQVRGGCSCAGPYGHYLLGIDPQTSKQMTDLIHAGDLSRKPGWVRLS
                     LHPMMTNQEVSY"
     gene            24922..25431
                     /locus_tag="J4I02_RS24785"
                     /old_locus_tag="J4I02_24490"
     CDS             24922..25431
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373808.1"
                     /locus_tag="J4I02_RS24785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24490"
                     /product="DUF1036 domain-containing protein"
                     /protein_id="WP_274483267.1"
                     /transl_table=11
                     /translation="MGLNFRNSTNAAIFVVFAYPDFSCTPVNYSKAGWYQVNPGQTIQV
                     WSGFPGGNTFFYYAEDDFGREWRGSYFTQVPENAFNWCWDTGCTTCRSVGLRRIAVSPF
                     VFDYTINFVTSSSQRKPASSTLRMTLPSKATQEKPILRRVPAKPKRLKQGKPQLQKRIT
                     HKKRTK"
     gene            complement(25536..26588)
                     /locus_tag="J4I02_RS24790"
                     /old_locus_tag="J4I02_24495"
     CDS             complement(25536..26588)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312675.1"
                     /locus_tag="J4I02_RS24790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24495"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_274483268.1"
                     /transl_table=11
                     /translation="MEIGISTFVETTPDPQTGEVISHAQRIREVVEEIVLADQVGLDVY
                     GVGEHHRKDYAASAPAVILAAAAAQTQRIRLTSAVTVLSSDDPVRVFQDFATLDGISNG
                     RAEIMAGRGSFIESFPLFGYDLDNYDELFDEKLELLLKIRESEKVTWKGGHRPAINNLG
                     VYPRPVQNPLPVWIGSGGNQESVVRAGLLGLPLVLAIIGGSPVQFAPLVELYKKAARHA
                     GHDASLLPVASHSHGFIAETTELAADKFFPSTQQSMNVLGRERGWGPYTRSSFDAARSL
                     EGALYVGDSDTVAQKIIHLRKQVGITRFLLHVPVGTMPHDDVMRAIELLGTEVAPRVRE
                     EISKWESESK"
     gene            26840..27595
                     /locus_tag="J4I02_RS24795"
                     /old_locus_tag="J4I02_24500"
     CDS             26840..27595
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822536.1"
                     /locus_tag="J4I02_RS24795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24500"
                     /product="AIM24 family protein"
                     /protein_id="WP_274483269.1"
                     /transl_table=11
                     /translation="MAFVINNLKDNSNVAITDQLGGFTVLEYITDLSCTSVAAAQDNYY
                     MSKSNMRRKQLMIEINNSEIMMKAGAMQYTVGSMEMTTGVKGVGGLMRNLVSGAVTGTS
                     AIKPHYKGTGTIMLEPTYQYIWLIDVDNDDIAIEDGLFLACDTTLDISVVARSNLSSAA
                     LGGEGLFNLSARGKGVLALQAPIPSEEAVVIELQNDVLKVDGNFALMWSNTLQFTVEKS
                     GKTKMGSAASGEGLVNVYRGTGTVWLAPL"
     gene            complement(27638..27979)
                     /locus_tag="J4I02_RS24800"
                     /old_locus_tag="J4I02_24505"
     CDS             complement(27638..27979)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822535.1"
                     /locus_tag="J4I02_RS24800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24505"
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="WP_274483270.1"
                     /transl_table=11
                     /translation="MSSLPNCPECNSEYTYEDRSLFICPECAHEWSTDSEAVSSEDVKV
                     VKDANGNILLDGDSVTVIKDLKVKGSSSVLKIGTKVKNIRLVDGDHDIDCKIDGFGAMK
                     LKSEFVKKN"
     misc_feature    28083..28096
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.09"
                     /tool="antismash"
     gene            complement(28235..29101)
                     /locus_tag="J4I02_RS24805"
                     /old_locus_tag="J4I02_24510"
     CDS             complement(28235..29101)
                     /EC_number="1.6.5.2"
                     /GO_function="GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426051.1"
                     /locus_tag="J4I02_RS24805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_24510"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_274483271.1"
                     /transl_table=11
                     /translation="MKIALTGATGQLGSIVVDTLLTSVSTNDLIVSVRNPEKAENLRSR
                     GVDIRHGDFDKPETLDQAFAGVDRLLIISADGDNDTRIRQHKAAVDAAVRAGVGFIAYT
                     SAANAADSTLFLAPVHRITEEFIRESGIPYSFLRNNWYLENEAGTIQSVLAGAPWLTSA
                     GSGKVGWATRADYAQAAANVLSSEGHENTIYELSGKPITQEEFAAVLAEVLGKDVPVQQ
                     VDDATYAEVMLGAGVPEGAIPIVVGIQQAIREGALDVVSNDFEKLLKRPLTPLSQGIRE
                     LIKQTQA"
ORIGIN
        1 cctccaccat tgatcctgtc atcgaatcgc tattgtagat ttctgttcac ttctttggat
       61 tcttcaaaaa aaagagtatc aaatgacaaa aacgaatatt tgtcatttga tactctttat
      121 gttatcctga cttcaaggag gtgactcaca cggcatttga ccgtgtccct atggaaaaat
      181 cctcagatgt gctaaccaag gaacagattc tcattgctac tgaagacaca cttaggcgtt
      241 ttggtgtagc caaaacctcc gtaaccgatg ttgccaaagt attgggagta agccatggca
      301 ccatttaccg acactttaaa agtaaagccg agcttcttga aggcgtgacc gaaaaatggc
      361 tgaatgaaaa gattatcgcc ccgttaacgg aggtctgtca gaattcatct atactgggaa
      421 cgccacattt aaaacgatat atacagacct tggttgaact caaacagtat tatgcccgcg
      481 acgacgagga aatgttcgag atgtatacga gggtcaccga gcaagccgct gatttaatcg
      541 accagcatat cgcccacatt gtggatcagc tcgctgatat cattgcacgt ggggacatca
      601 tatcagatca gccaacccaa ctggcgcgta cccttttcta tgccacagcc cgttttcatc
      661 accccgctca tgcttacgaa tggaagaatc ctttgattaa tcaggagttt tcggatgtgt
      721 ggatgctttt agaaaaagga atcacttaaa atagatatgg aaggaaggtc caaacacata
      781 tgaagcattt ggacggaaaa acagcaatta tcaccgggtc ctctagagga attggacgtg
      841 ccattgccga gcaactggct gatctgggcg ctaatgtagt catcaattat gccagcagtc
      901 cggacaaagc tcaaaaagtc gtggagagga ttattcaaaa aggcggcaaa gccatagcac
      961 ttcacgctga tctgggcaaa atgagtgata ttgaagcatt atttacaaat acgattgctg
     1021 aattcggtaa agtggatatt ctggttaaca acgctgggat gatgatcacc caacctttgg
     1081 ctgaggtaac cgaagctgat tttgaccaac aattcgcact gaatgtaaag ggcactttct
     1141 ttgcctgtca gcaagccatg aaatatatgg agaactacgg aagaatcgtg aacctgtcca
     1201 catccgtgat cggacaaatg ttcccggcat atagcgtata cgcaggtacc aagggcgcag
     1261 tggagcaatt tacccgtcag ctagccaagg agttcggaaa caagcaaatt acgattaacg
     1321 ctgtggctcc cggtcctgtg aacaccgagc tcttccaagc aggaaaaacc gagcagcaaa
     1381 tcgaagccat gaaaaaaatg aatgctatgg gtcggctcgg cgaaccggaa gatatcgctg
     1441 atgtgattga gttcctggtc agtgccaaat cacagtgggt taccggacag acgatccgcg
     1501 tcaatggcgg gttcatctaa aagctggaat acatggaatg gaggctgtta cgttcatgat
     1561 gttacacaaa ggcgagacct tatttcgaca aggagaatcc ggccccttat atcacttaaa
     1621 gagcggcttg ttaaaaattg tccgcgtcca tgaagacggc tcgcaaattt tagttaatgt
     1681 gattgtgccc gatgaaatca tcccgcacca ctccctgatc agccccaatc cttattatgg
     1741 tacggcagtg gcattggtaa cctctgaggt tggggttttg tcgcaaaaag aatggtacca
     1801 ggcgctggag caagacccaa ctcaatgtcg ggctatcgct ttgcagctac aggacaagtt
     1861 gcgcatgatg cagcaacgaa ttgaccagct caccgaggtg tcacctgccg agaagcttcg
     1921 gaagcttcaa cgctggttcc actcctacat cgcacccgcc acgttaacgg acgtgctgac
     1981 gcaggaggag atcggtcagt ttatcgggct acgccgggag acgattaatc ggctattgcg
     2041 tgcttcaagc gctccttctg caaaagatga tgacgataat gcatctcgat gagcgaaaac
     2101 cactctccag cattcaacgc gccgaatctg ggatgagaaa cagtagacgg ccctgttgat
     2161 ctcccaacgg tcggctcaat ctctctcatt ttacggatta caacatttaa accctctaca
     2221 atttcttctt tgctcgtcgg ttgtggagga gtatactgcg gagatggtgg aacttggata
     2281 cgtatgggcg gaaatcctcc tagattaaaa atggccgtac ccgcctccgt tttaactcct
     2341 gtctccccat taggctgtag acaaagatca atgttcttaa gatgcatata cagagcagag
     2401 ttcaccaaat gaagatacat ttgtccaagc gaccattggt cctcctgcgg tgtgtactgc
     2461 aattgctcca agctaaagct gtccacttca agaagatagt gttgtgccgt ttcttcaaaa
     2521 cgctgcaatg tttcggttgt attcatatat tagtaactgc ccctctctat taatgtagct
     2581 ttactataca aaaatgctac tgacagcatt atgtcagtag catttcaaca ttttttccac
     2641 ttccgcacgt atccgctccc ggagcgactc aggctccagc acaaccatat ccgctcccca
     2701 tccaagtatc cattgcagta attcctccgg ctgtctgacg cggaagagta tatgcagtcc
     2761 atctgcacgc tcctctatgg cctccatata aaagttgttc gcttccttca ccttatctgc
     2821 gatatccaaa cgtgctagta tgcgaacagt tacatgacgg tcatcggttt gcttgtaatc
     2881 ctgcaaatga aaatcgacag gcaactgaaa cctgtcctcc agcacgataa gctcgtccat
     2941 acgtgacaga cgaaaatggc gaagctgctg ccgcaattcg cattgcccaa ttaacaccca
     3001 agaaccacgg agcagtacaa gaccataagg ggcgaccaca cggacacttt gacgattccc
     3061 gtcagcctct ggcattcttt tggagtagcc aaaccgtacc tttcgttttt ccaatacagc
     3121 gagacgtagc ttttccaaac aggttttctc gctatggttt gccccttcac ctaccgcgag
     3181 caatctgatg gtcgtacgca cccgggaaac ttccctgcgg acgctctccg gtaaaatggc
     3241 ttcaatcttc ctgcgggagg tttgcgcctt gatgccgtag tctgtatcaa atttttgttc
     3301 gacaaaatcc gttccgatta gcaacgccac agcctcttct gcggtaaagc tcaagggggg
     3361 caggaagtac ccctccatca aggaatatcc aatgcccggt gctcctacaa tcggtacgcc
     3421 cgattcactt agagcctgaa tatcccgata gatggtcctc acactcgttt cgaatatggc
     3481 tgccaaatcc tcagctcgta aaatatcctt acgctgcaac tctagcaaaa tcgctagcaa
     3541 acgatctgtt ttgttcatac cacggcccct ctctggaagg atctaaaatg cagaaataca
     3601 aaaaagcaat aagggcagta cagtcactgc gacttattgc tccttttttc acacagaagt
     3661 tacttcatta cttaaaaaat actttttcga cgttatattt agccttttgt gtattgatga
     3721 tgtaggtttc atagatttct cgctctactg catcttccac aatacaaacc tcaataatcg
     3781 ctacttcatt tcgcttgtcc ttgatcggcg atacgttatc ttcaaaatgc tttttgattc
     3841 ttggtcttag ctttcttgct ttaccaacga acagcaattc ctcctgcgca ttgtagaaca
     3901 taaagatacc tgccttatcc ctagggatca ggtgaaagtc ggtaaatccg taaatatggc
     3961 tgagctcagg gttaacctgt ttggtaatcg tgatatccgg agttggaatc gttatattaa
     4021 tcactatgtc acttcctcat tctatatagg tgtaaatatt atcacaaatc ctgcggtaac
     4081 accatttaag atcgtcaaag ggaaggacga acgatgacaa ataactcagg cagataccga
     4141 tggacattaa aaaagatgac cctgatgaat acacagagcc acctcttatt gtctatagct
     4201 tctttcgtaa tctgttcacg agagaaggta ccgtcatttg gtatcaaccg tttttgtaat
     4261 ccgtaatgcg gtgatacatc gttttatccc tcagcttacg gaaatgggac cttgccggaa
     4321 aaagattagc ttcaataatc ccaatacgtc cttttcggtc tattccaatg tccagtccat
     4381 atatacggtg ccccgggaaa aaagtgctta atctcttcgc ggaacggatg gaaacacgat
     4441 taatatggga ctctaatgta ctggcagaca ggtgtcgaat ggaagattgt cgaatgccgg
     4501 atttaaaatg gtgtagtgtt cccttactcc gtgtattgtt ggaaacaata tagcctttgc
     4561 ctgcaacttt gataaccttg cctgtgacta cccatacaga tgagttaatt ctccgttgaa
     4621 tgatgactct catatcaaaa gggcgtttgt tgatggtcgg acgggtaatt ctgcgttgaa
     4681 ccatataact ggcgttcccg atttttcttc taatataata atacgtattg gttctgcccc
     4741 gtactaaaac ttttttattc tcgtaatgta caaggtactt atggtgtcct agccaggaga
     4801 cctggaaaat cccctgtcca cgactccccc acaccggttt cacgataaca tgcacgtact
     4861 tggagagcag tttcgaaaaa tgatacctgt ccaggagctt cgtttcggga acgtaagact
     4921 tcagagacgc ataccttctc aataacaaat atttgtacca cttatctttt gctgctgatg
     4981 gcatgaggac tccacctttc tcatccgcat tttatgctac tgagatagct ttcaagcaac
     5041 tctaaaaaca actccatttc cttatacgta atatcaccta tattggcaat ccggaacgta
     5101 tttagtttct caagtttacc gggatagatc ataatacctt tgctgtaaaa ataatcatgc
     5161 atagattgaa aatcataacc tgcacaatga ggttcaagaa tggaagtaat gattttggag
     5221 tgatgctcct cgggaatgat ataggttaga cctaagcggg ttaacccgtt aattaaagtt
     5281 ttccaggatg tcgcgtacct ttcgtacctt ttatccaccc cctcttgctt taattcctca
     5341 atcgcttgcc taagcgcata taaggtttgg actggggggg taaaccgcat ctgtccatgt
     5401 tccacaaaat agttgtattg agcatacaaa ttcaaataaa agcttcttgg cttctggtct
     5461 ttcaaatttt ccaatttgct ctttcttgca atcacaaacg aaaccccggc cattccctgt
     5521 aagtttttgt tagagcttgc ggccaggtag gcaatgttca tctccttcaa ctgaattgga
     5581 atggctgcaa atgagctcat ggcatccacg atcatgtcga tttgatacct tttgcacaat
     5641 tctccgatat ccttcacctt gttaagcagg ccagttgtcg tctcgtgatg aacgacggcc
     5701 agatgggaga ctgtgtgttc agaagattgg atgtaccttt ctaattcagc caaatcaata
     5761 gcactatcgg gaggactttt gaattcaaga taatccactc cataaacctt cgctatctca
     5821 cacatccgtt ttccataggc cccattgctg acaatgatca ccgcatcgtg attcggcacc
     5881 gaactgatga tagactccac cgccgcagta cccgacccgc caaacaatac ggtcgcataa
     5941 tgatccgggt ttgcgaccag tcgggtaagc tctgtagaaa tatactccat gatttgacca
     6001 aactcggctt cacgaggaca aatatccgga accacctgtg accatttcac actttctgta
     6061 gtcgttgccg gaccaggggt aagcaaaatg tttttcttga cggaagaact catgaaccgc
     6121 ccactccctt gcccttcaaa ggactgttat gaataaatcg ctgcagacgt tcctttactt
     6181 catgaggctt catatgtgga cgagcaagct gatccttgga atgcttggat attttcaggt
     6241 acaaaaacgt aagtccttta tccactttcc attcttgtaa acaagccttc agttcctcga
     6301 gactgtgaac ataaatcgac ttcgtatacc cgcaggaagc ggcaatgtct atgaaatcga
     6361 cattatggga taccgtactc tgaccacctg ttgattcatg agcgttatta tcgagcagaa
     6421 tatgaaccat attagctgga tgataatacc cattggttgc cagactcccc atacgcatca
     6481 acagagatcc gtctccgtca atcacgacga tatctttgct tggttggctc aaagccaaac
     6541 caagtcccaa ggaaccgatg catcccatag agcctaccat gtacaggttg ttagctgcat
     6601 cttcaatttc atacagctca cgtccggtct taccagttgt tgcgagctgt atggtatcgt
     6661 cgtctttcat ggagttaatc gcagataatg catcataccg tgtaggcatt tgatggcccg
     6721 catgaccatg ctgtcggatc tgatttaaat gaatggaggt ttccagtttt tgcaatagct
     6781 ttttgtcaaa cgtccctttc ttcacgacaa aaaagaacga gcgatgccgg gcaatttgct
     6841 catcagcctg gatcagctga gttttggcct cttctaaatt cttggagaga tactgccatt
     6901 ccacacccat cacatccagc atttgcgttg ttatccggcc catcagttca tgctggggtt
     6961 cgtcaggtat ccccggttct ccgcgcaggc tgacaaatcc aagcagcgga atatgaaaag
     7021 ggtaattaag agaggtcagt ggcgaaatag cgttggtcag ccctgaattt tgcataagga
     7081 ctaccgcctt cttcccccct atataagctc cagatgcaat ggcaactgca tccccttcgt
     7141 tagccgctgc aacataatcg cattcgttta tcgcataatt gatcaaactt ttcaagaaag
     7201 agcatggcac gccgctgaaa aaggtaaaac ctaatttttt cagctcttct cctaacaatt
     7261 tcgtgtccat tatacgtgct cacccgaatc cggttctgac gatgggaggt attttcgttc
     7321 cgcagcttgc agctcctcta ccccttgaag ccggaatact tcttcgaggg ttgcgacgct
     7381 cttttcgata tggacaaggc tttcatcccg ataaattcgg tcagataatt gtttcatggc
     7441 ttggatggat gctctcaaat tatggtttgc ccaaatcaca aggctgatcc ccatctcctg
     7501 aaacctgacg gttggggttg tatagtattt ggtaggtacg atcactactg gcaatcttcc
     7561 ggcccattcc ttcatgaacg cttcaatctc ggcggcatcc gatcttttgc tgtgtataaa
     7621 tatggaatcc gcacctgcct tccgatacgc ctccgcccgt tgcagcgccg ctttaagccc
     7681 tttcccggca ataaatgcct ctactctggc caccaccgta aaatcctcgt ccgtttgcgt
     7741 atctttcatt gctttaattt tcccggaaaa ctcctcgata tcagccaagg tctgtccttg
     7801 accgttaatg aaagaattcg ttttggggaa ccgtttatct tcgatgcata ccccagcaat
     7861 atgacgctgc tccagtttcc tcaccagccg ccttgcatta ttgaagttgc cgtaccccgt
     7921 atctccgtcc agcaaaatcg ggatggaggt agcatcactc atgaattcca aaacatccaa
     7981 aacctgcgtc caagaagctt cattgctgtc cctgactccc attgctgcag agatggataa
     8041 cccgctggcc catattccct taaaccccgt ctcctccaca attttggctg acagaccatt
     8101 atgagcttcc atgataaact ccagttttcg ggaattaatc aactctctta gctgctttgt
     8161 ttttttcatt gaaactttct ccttctcccc taaaaatagc gtgcaaggat ctacttccga
     8221 ataagcctct tgtttctcat gatcgttttg atcatcgtag gatcgggaag ctgggtaaac
     8281 agcatatgtc cggggtgtga attggcctcg ataatccaaa tacggccttt tttatctatg
     8341 gcaatatcga cccccaattc gcgaaccgga tgccgtttat taaccgtttt ggcaatgatg
     8401 acggatagct tagagattct atgataatag gcatctgctt tcgtacggtt gtgcttaaaa
     8461 aggctgaaaa gagctcgatg caaagatact gcatgccctc ctttaagata attggtaaca
     8521 tacttatgag gtgccgcgac acgggcggcc gctccggaaa tcacccattt tctccctggt
     8581 ttctgtaagt atatcctggt gtcaaaaatc gacccgtgat acttagctaa ccgaagtcct
     8641 ttctgtacta agtacatgtg tctggatttc tggtatgact taattgcttt taaaacaaaa
     8701 cgagatccaa cgatccttcg acttgagccc ctacgaacct catatccttt tttcaatctc
     8761 ttgacccgga tgatcccgct gccaccactt ccgaaattgg gttttatgaa gaccgatgaa
     8821 taggtattca gcatccgcga ggtccttgaa tccgtaaacc aatgggtttc aggtaaatgc
     8881 ggacgcaaaa cgggatgttg caacatttct ttatgctttt tcatttttcc aataggcact
     8941 tgtcatccct cttatctttt tgggtttctg cgcatacagt atgcatatgc atccagatcc
     9001 ccttctgcgt gggccgctac ctctgctaga aaccaagttt atgttacaaa aaggcatgtc
     9061 ccagctgtta taaataccac cccccctagg agacaccctt ttggacagac tcggggttcg
     9121 gaccaaagaa aataggctgt cgccaaataa caaaagatcc gctaccgaat aggtggcgga
     9181 tcttttgttt ccagcaagca ctggtgacat agtctactct cgtgccaggt gatatatgac
     9241 tcatggccaa atagctgctg cttgcctaat tatcgctccc ccgggacaag cttcgtcgtt
     9301 tttcccgcac ttctttccag tatccagaca agaaccccaa gtcgcagccc caaggaacac
     9361 ggagatagta cccaaagtct tgaataattc cccgttgcct ccacctcctt tttcaccggg
     9421 gcgtccgccc atgtgccctg gcacattgct tacctctcct cccggcggtc gcaggccaag
     9481 tccgcccccg gaaaccgaag gcgtgtagta atagtagatt acgagcagag ctgctaccgt
     9541 aactgcgatg attgccggaa tccaaacggt ctttttcgtt ttcattagtt atgcatcctc
     9601 tccgggaaaa ttgccttgat tgtacccggt caagctgaaa acaggattaa agctagctga
     9661 aagtattcct tttacctcag tcagtatcga gggtggtcgt aataacgtta atacaggcga
     9721 ccgtaacaga taggaaatct atgaattccc tactatgcga gtacgtcggt ttccgttaca
     9781 atatgtcagt gtgattctgg catcggcaga ttgacgcgta cttgaacatt attggaggct
     9841 tctatttttt catgcaaaat gaatctcatg ctaacgtaaa aatcataacg gccgatccga
     9901 gtgcgatcgg cctatttggc ttggcaattg taacacttgt tgcttcatcc caaaagcttg
     9961 gtctcaccga aggcttaagc tttattatcc cttgggctat atttctcggt gcttttgcac
    10021 agctgtttgc ctgcattcag gatgcaaagc ataacaacac cttcggcatg acggcatttg
    10081 gtgcttacgc cttcttctgg ttggccgtag ccagtagctg gatgattaaa atgggcgtat
    10141 tcggctcaga gctggcatct gctgtagatg gcaaacagct cggcttcgcc tttgcgggct
    10201 atctcatctt tacgctcttc atgactattg gagcgatgga gacgcataag gttttattct
    10261 ttatttttgt gttgattgat tttctattcc tcggtcttag cttcgatgca tttggcgttg
    10321 ccccagaggt gttccatacc atcgccgctt atgctgaaat gggcattggt ctgctctcac
    10381 tgtatggcac aggagctgcc gttctgaatg ctcattttgg ccgtacattc ctgcccgtcg
    10441 ggcgtccttt cggcattttc aagccacgtc cttagctgta tatgtaaacc cacaaagcgc
    10501 ctttcgcgcc gatccgcgtt aaggacggct ttgtgggtta tatggctgga gctattcggt
    10561 acccagtgca gaaacttgaa atttagtgaa tataaaagcc tacaatgata acaatataca
    10621 taagttgtaa tcaaaggggt gtttgtaaaa atgacacaag acgagtctcg caccacattt
    10681 ccgcaatttc ccgaagcatg acgaaggggc ggtcattcgg gtaaacggca aaagagcggg
    10741 cgcataccga gacccacaag gagcattaca cctagtggac acaacatgca cccatatggg
    10801 ttgcgaagtc gagtggaatg aagcggaaag aacatgggat tgcccttgtc atggctcacg
    10861 cttttcatat caaggcgaag tcattgaagg accggccaaa aaatcgcttg gcaaggttga
    10921 aaatagctct gaataaacat agttacgctg ggacaacata tctttgagaa ccataaaaga
    10981 aaggtgatcc tatgatggtc gataccagac aagacaattg catcaaagtt gtgcttaaac
    11041 cttaactata tattggaata ttggaggtaa acgtcatatg gtgtatggcc tgcacgaaac
    11101 ccttgaagtc catgaactgt cagcgttcaa aacagtatgt cttaccaagt ccaaaacaat
    11161 acaagcattg atctctgatc cgactctcaa agctatatta cagcaggatg ttgacttatc
    11221 gacccgccaa ttacaagaac tcggcaccct cttagatcaa gccatttcac aggaggttaa
    11281 gtcatgaata cactattgga gcatttgacc ggactgaata ccttaacgga ccaagtcatt
    11341 gcagccgatt ttctgaacgc agccaaaagc ggtgtgagaa attacgctat ggccgtaaca
    11401 gaagcgggaa ctccagaaat taaggcaatt cttacaaagc aactggatga agccattgat
    11461 acgcatgagc aaatttccac gtacatgatt gaacgcggct ggtatcaccc ttggaacgta
    11521 aaagagcagc tttcgatgga tctgcaaaat atcaatactg cattgcaagc tcccgttttg
    11581 taaaaagaaa actttggccg tttttttgct cgttggacgt ctctttggca ttataaaaag
    11641 tacgttcttg cttatctatg aaacccgcaa agccgtcttt cacgcccatc cgcgtgaaag
    11701 acggcttttg gttttatcac agtatcttca ttattcagct tgccaattcg gcatccgctc
    11761 tgcaggataa cgaaggcctg ctgccattcc tttggggatg attgcgttaa tagtctccat
    11821 ttcttctgcg gacaaaacca catcaactgc tcctgcattt tcctctagat acgtaacccg
    11881 cttggttcct ggaatcggta caattccctc ttgcgcaagc agccatgcca acgccagttg
    11941 agaaggtttg accccttttt gagcagcgag atccttaata tgcttcacga gatccagatt
    12001 tttttggaaa ttctcaggct gaaagcgtgg cacggtacga cgaaaatcat cttctgcaaa
    12061 atcatcaaac ttctgaattt gcccgctcaa aaagccgcgt cccagtggac tgtaggccac
    12121 aaactcgatg cccagctccc tacacgtcgg tataacttca tcttccgctt cccggctcca
    12181 taaggagtat tccgtttgca gagctgtaat cgggtgtacc ttgtgagcgc gtcgaatgag
    12241 tgcaggagaa gcttcggaca gccccaaata gcggactttt cctgcctgaa ccaaatcact
    12301 catcgcgcca accgtttcct cgataggtac attcggatcg acacggtgct ggtagtacaa
    12361 atcaatcaca tctactccca gtctttgcag gctgcggtca catgcctctt ttacatattc
    12421 aggacggccg ctgacaccca ggaatccccc atcttcccca cgcataatgg aaaatttagt
    12481 agccaatatg acttcgtcac ggcggctccg caaaacttgg ctaatcagtt tttcattttt
    12541 ccccacaccg tagacatcgg ccgtatccca gaagttgatc cctagctcca gcgcacgatg
    12601 aagcgtattg atcgactcct gatcattcaa ctcaccgtaa tattcggaca tacccatgca
    12661 gcctagaccc agtgcagata cttgaaggtc actgttaccc agttgtttct ttttcaattt
    12721 caatcactcc ttaattgtta gaatagtcat cgcatttcct aattactacg tcacattccg
    12781 tatgttacta cttaaagtta acttgaagtc aagcattgtc tggtttgaaa ggagaattat
    12841 tatgtatgaa cagaagcgct tcagttgctt ctggacggca ggggaattca tttacaaagc
    12901 tgtagcaaat acacaatttt tgctatacac tttataaaag aggagcttgc aaactcctaa
    12961 aaaagtaaaa agtggtgaaa tcgttgttca aaatcttact aattgaagat gatgaaactt
    13021 tgttccatga aatgaaagat cggttaactc aatggaacta tgatgtgtac ggcatccagg
    13081 actttaataa agtcattcag gaattcacaa cgataaaacc tgatctagtc gtgatagata
    13141 ttcaattgcc aaaatttgat gggtttcatt ggtgtcgaat gattcgatcc cactctaacg
    13201 tccccatcct cttcttatcg tcacgggatc atcctacgga tatggtgatg tcgatgcagc
    13261 ttggagcgga tgattttatc caaaaaccgt ttcattttga tgtactcatt gcaaaattac
    13321 aggcgacact ccgccgcgta tataattaca atacagaacc cgtctcccta aaaacatggc
    13381 gtggagcgac ggtcgattat gaaaaaaatg tagttgccaa tgaggctggc tccatcgaat
    13441 taaccaagaa cgagattttt attttgaagc tgttgattga acaaaaaaat aaaattgtcg
    13501 cacgagagga attaattaaa agcctctggg atgatgaacg ttttgtcagc gacaataccc
    13561 tgaccgtcaa cttgaaccgc ctgcgtaaaa agctagacga gctggatttg agccgtttca
    13621 ttgaaacgaa agtcgggcaa ggctacatgg ctacagaaga ggcacctacc aatgattaaa
    13681 aaatatctta tagagaggcg gagctggatt ctactgtttg tgtgtcagca attcctgatc
    13741 ctgttcatcg cttatgtgga tgcagcaatt ccattaatgc cgatccttta tatcgtcttc
    13801 ttatcgatga tgattttctt ggttttttta atcattcgtt atctcaagga aaccaaattc
    13861 tataccacat tagaagaatg ggagagccct ctagaactaa cgggtatagg cgaaccggag
    13921 agtccgtttg agcaaatcat tgaacaaaaa atcactgacc agaccgaaca gttacaacag
    13981 gtcatctcgc aaaatcaatt gacacttgaa catgaaaaag atgaactatt atcctggatt
    14041 catgaggtaa aaacaccttt gaccaccatg catttgatga ttgagcggtt ggacgataag
    14101 cccctaaaag ctcagttaac ctatgaatgg ctacgaattc acttactgct ggatcagcag
    14161 ctccatcaca aacgtatatc ttttattgaa aatgatctgt atatcgagca agtgaattta
    14221 aaatctctgg tttttaatga aatcaaagca ttacagtcat ggtgcatcca aaaagggatc
    14281 ggttttgaca tccaattggt gcacatggaa gtactgagtg atgccaaatg gctggccttt
    14341 atcatcagac agctcttaac caatgccatc aaatatagcg atgccagtga tattatcatt
    14401 cacagctatg aacaaaggga tcgaatacaa cttgaggtcc aagactttgg acgcggtatt
    14461 gatccgaagg atataccccg tattttcgag aaaggtttta cctccacaac ccaacattct
    14521 gatcatactt caacgggcat ggggttatat ttaacgaaaa aggcagccca gtccttgctc
    14581 atacatatag atgtgcactc caaaccgaat gtgggtacaa ccttcacttt aattttcccc
    14641 aaacgaaatg atttcgtgag tatggtaagc atgtgacaga gatgtcacat gcttttatgt
    14701 attgttcgcc caatcaaagg aaaaacatcg attctatttt tataataagg ctacaagaac
    14761 aataaggagt gcatcgaagt gaatatttta gaagcccata aaatccataa aagctacggt
    14821 aataagttaa atatgcagga ggttttgaag ggaatagata tccttattga agaaggggaa
    14881 tttgtcagta ttatgggcgc ctccggttca ggtaaaacca cactgctgaa tgttctttcc
    14941 tctattgata aagtgagcca aggttccatt aaaatcaatg atatcgaaat gacgaaaatg
    15001 aaagaaaagc aactagctga atttcgcaaa aagcatttag gctttatttt tcaagagtat
    15061 aatctgctgg atacgctaac cgtgaaggag aacattctct taccgttatc catcaccaaa
    15121 acgcctaaaa aagaagccaa ccaaaaattt caggaagtag ctacagaact gggaatttat
    15181 gagctcaagg acaaataccc caatgaaatc tcgggtggac agaaacagcg tacatctgcg
    15241 gctagagcgt ttattcatga gcccagtatt atttttgccg acgaacctac gggtgcactg
    15301 gattccaaat cggcttccga tttattaaac aagctgggcc agttgaacca aaaacgcaag
    15361 gcgaccatta ttatggtcac gcatgatcct gtcgcagcca gccattgcag tcgggttatt
    15421 tttattaagg atgggcaatt gtatacgcag cttcacaaag gcgagcagga aagacaaagc
    15481 ttcttccagg atatcatgaa aacccaaggg gtcttaggcg gggtccaata tgaacattaa
    15541 tctgctcatt ctaaaaaatt tgaaaaaaaa cctgaaaaat tattaccttt atgtttttgc
    15601 cctcattttc agtgttgcac tctatttcgc ttttgtcaca ctacagtacg atccctccat
    15661 ggacgaagtg aaggggtctg ttaaaggtgc agcttccata cgggcagctt ccattttact
    15721 ggtcgctatt gtctgcattt ttcttatgta tgccaataat atttttataa aaagacgaag
    15781 caaagagatt ggcctatttc aattgatcgg aatgactaaa agtaaaattt ttcgcatttt
    15841 aagtgctgaa aacctaattt tatactttag ttccctcttc attgggattg gggttggatt
    15901 ctccttttcc aaattagtga ttatgatttt atttaagacg acgggcgtcg aagccattgc
    15961 cactctatat ttctctaacc aagcactgac tcaaacactc atcgtttttg ttgtcatcta
    16021 cctgctgatc atgctcatga attattcttt tatcaaaaga caaagtattt tgtctttgtt
    16081 cagagtgacc tcaaccaccg aagggaaaat caagaaaata tcgatctttg agatgatcat
    16141 cgggatcatt ggcatctctc tcatcgcttt aggttactat gtttcctcca aattatttgg
    16201 tggagacttt acatccataa atgaattgtt tatggctatg gtgtttattt tgggcactgt
    16261 catcatcgga acactacttt tttataaagg atctatccgc tttatttcca atatcatcag
    16321 aaagagtaaa ggcggctatt tgaacattaa tgaggtgcta tctctctcat ccattatgtt
    16381 ccgcatgaaa tccaatgctt tgttgttgac tattattaca acagtatcgg cacttgccat
    16441 cggtttactt tccttaagct atatcgccta ttattctgcg gatcaagcag ctgaggacaa
    16501 tgtaccttcc cattttgcca tgacgaatgt accggatgcg gagaaattca aagcgttact
    16561 tcatgagcat gatataaagt atcgtgaaaa gaaaattgaa gtgattcaag tcagtgtgaa
    16621 gacagcacaa attatggaga ctcctatgga acaattaaat gatggtacgg attccatgac
    16681 actgcctgtc gtaagcgacc aatctgtgga gggtacggat gtaaatccag gccaaacggt
    16741 tttaacgggc tataatgata tgttacagaa attcatgtcc ttgaaagact ttggaccctt
    16801 ggatttgaag gggaaaacag aagtcatacc tcaacgatat gtgggtctaa aaaaggatta
    16861 tgtcattccc tactatttta cagtcggggg agtacccact gtcattgtag acgaaaccat
    16921 ctttgagcgg ttaaagaaag atgtaaatcc aaagatccaa aagaagtcat ccttgtatat
    16981 tggaattgat atgcttaatg aagcacagat tgaagaagcc gatcgcctct ttgcagctgc
    17041 gaattttaat gatcaacaat catcacgcct tgaaatgagt agcaatcaga agcggagcat
    17101 gggagtgatc atgtttgtag ttggattttt aggactcacc tttctcatta catcaggctg
    17161 tattctttat tttaagcaaa tggatgagag cgaagatgaa aaagccaatt acaccgtgtt
    17221 aagaaagtta gggttcacac agagcgacct gcttagaggc attaaaataa aacaactctt
    17281 taactttggc attcctttag taattggcct atcacacagc tatttcgccg tccaatccgg
    17341 ctggttcttg tttggaaccg aaatttggag gcctatgatt atcgttatgg tgctgtatac
    17401 cgccttatat tccattttcg ggatactatc catcctgtat tataaaaagg tcattaaatc
    17461 agcattgtaa tcggcaaaaa gcaaaaaaaa gccccaggca aaagtgctgg ggcttttcca
    17521 aatatttgag cattttcgtt tctacatgta caataaaata actatcatcg taaccccaaa
    17581 gggggagagc ctattttatt attaatcatc aatggcatta gcatcgtggc caatatcata
    17641 ctcggttcct ttataggcgc agctattttt atgggaatcg tttttttcct gattggctgg
    17701 cctgagttta aaaaatcgcc gaagcttacg aaaaaggcaa aaaaagatat cgcctatatt
    17761 atgtccacat tgttaaccct tgttgtattc atggttatcg tttgctggaa tatccgcgcc
    17821 tcaggtgatt tgatgctagc tggtccgcta acaccacaaa tgaagtttca ctggggacaa
    17881 aaggtgttga tgctagggtt actggagggc ttatgggctg tcatcaccct aaaatggctg
    17941 ttacccatct tttttgatcc gctggatctc agtaagaagc aaatccttgt tttagtaagc
    18001 gggattgtat ttagtgtagt ttcaggtatt tatgccatgc ttgaagcaag ttaaaaaaac
    18061 ttaacgcaaa ggttcaaaac cctctgcttg cttcagaatt cgctcaattt ccacgcatgt
    18121 ctccggttgc agcgtcacat cgactgcttt tacattttcc tcaatttgtg ccggtttagt
    18181 agccccaata agtgcagcgc tgatacccgg ttctctcaaa atccaggcaa gcgcgagctg
    18241 tgacagagtg acacccaaat ccttcgccag cttatccagc tcctggacac agtttagaac
    18301 ggtatcgttc atgtaactgc tgataacatt attgaccgag gcatcagccc cacggctacc
    18361 tgttggtaaa ggttgtccag gcttgtattt acccgtgagg ataccttggg ccagaggcga
    18421 aaatacaatt tggccgatac ctaccttccc ggatacggga agtacctcat gttcgatata
    18481 acgttcgaac atattataga tcggctgatt agcaatcaat ggccgcaaat tcagcctttt
    18541 tccaatccca tgggcatcca tgagctgggc agcactccat tcgctgacag cagcgtacag
    18601 aatcttaccc tgagcctgaa ggtcatcgag cgctcgcagc gtctcttcca aaggagtgtc
    18661 tggatcataa cgatgacaga agtacatgtc gatataatcc gtacccaggc gcttcagact
    18721 cgcttcacat tgctccataa tgtgcttgcg tgacagtccc ctgtcattgg gaccggaatc
    18781 catagggaag tacaccttag tagataatac atagctatct cttcgataag acttcaaggc
    18841 agctcccata gccttttcgc cttctccccg gttatacgcg ttcgcagtat caaagaaatt
    18901 aatcccgagt tcaaaggctt tggcaataca ggtatgagct acttcctgct cggcggctgt
    18961 accgtacgtc aaccagctcc ccaagccgat ttcactaatt ttaagaccac tgttgcctac
    19021 atttctatat ttcatatcta ctccttcttt cataagaaga tcatattttt atattttaac
    19081 atgtaaaccc tttcattaaa atcattgata aagattcatg gagttacatg aaggatttcc
    19141 accaccctga ctgttagggt ggtagatgct tatagcctca caatctcaaa tcatatctac
    19201 ttgcttccta caggaaaaag cgcatcatat gcaggacaag gcagtttgtc gagaaactcc
    19261 tgaagctgct tcggtttatt tttgtaaata tcctttaagg atgttccatt ataaatattg
    19321 ccgataacca caggatggca tagctcacag atgaggatgt ccccgttccc atgcagatgg
    19381 agctgctttt taccatcaac acaattggaa aaataaacac ccggctgctc cctgaagccc
    19441 agtgcttctg caaaacgatc catgcaggtg aaatacaaca cagtatcgtc ctttttatgc
    19501 gcaatcaggt catgaacgga acgaacgagc gcttccttgg tagaaatagc gttccagttg
    19561 gtatgatcca tcacgatgct gttttggatt tcatggatgc gcacaccgag ttcatatacc
    19621 atttcactaa tagctggcat gttgttctgc gtctccgcaa acagcaacgt ctccagcacc
    19681 gtttccagct tggcttcggt acataaccgg atattttgaa cgattttctc atacatgcga
    19741 ggatgaacat gataataagc tgcatattta tcggcttccg tgaagttgaa agagatatga
    19801 atgttcgaaa gtcctgcatc acgcagtttc tcaattcgtt ccggactgag caagctggca
    19861 ttagtattga gctgggtagc gattcccttg tttgaacagt gagccacgat gtccagacaa
    19921 tcctcatact tcaaggtcac ttctcccccg gacagtcgca cacgttttaa cgttggaatg
    19981 tcatcaataa tatcaatgac ctctttgctg ctaatgcatt gcccgtcgtt ccgctgatat
    20041 gcgcagcagt aatcacactt gaagttgcaa ttggaggtaa ccccgacctc cagtccctct
    20101 agctcgtaga tgcccggctt ttccagttca agtgctttat atttgttctc tatactcact
    20161 ttctcatgat cctcccgatc tcaggcttgt gtcttgaatt cccttgagat tatacagaat
    20221 aggacggttt gtagatatga cattggtaac ggtgaaaatg gagttccgaa aatttgaatt
    20281 aaaacaaaaa gaaacctgca tctaaaaaga taggtttctc gacagtctta aagccttaaa
    20341 tatatgtttt aaaatgctgt gctatagtta cacttgctta gctacatcag agaaacgctt
    20401 ggatatatcc gtgacatttt gcaggccgaa atcaagactt gctgccaaat atttattaaa
    20461 aaagtcagga acaattccgg tcatacggta aaagaaggat acttcagttt tccaatcatt
    20521 ctcaaccatt tgatggatgt tcacgaggcc ctttttagaa acaaggtcga taattgtttt
    20581 gatttttgtt ggtttctgaa ttgtaattaa ttcatcgagt ggttcaattt tcaaataacc
    20641 ttttcgatgt aaagctgcat agaagttccg atgatctttt ggtttaagat ttcccaaatg
    20701 ggccgccctg tatcccaaca cttgcagcga agtcttccat ttctttttca aatccaagta
    20761 attatctgga tttgtgatat gaaccacatt tttcatatca agtgtaaatt cgtcttcagg
    20821 taataagaat gctcccgcaa acatatttgc ttcattttca ataattttgt gttcttttcg
    20881 atctaaattg gcaaattcaa ggcgataatg aagcaataga tgtcccagtt catgtgctac
    20941 atcaaagttt ctccgaacgg ctgatcgttt catattccct aatatgatat aaggccggtc
    21001 gttttgagtc cagagactat aagcatcaat ctcgtcgccc attgccttct caaaggcgaa
    21061 tactccactt ttttcaacta gaaacataag atcgtcgttt gtatcttgcg ctagtcccag
    21121 tctttttcgt gccaaatgag caactttatc aatttgagtg gatctatcgt catctgaatg
    21181 gtttagatat tcgataactt catcccttaa gctgataatt ttgagggtag ggaggctaac
    21241 tctggctgtg atatagttaa taaaagcatc taaatattca acatgcttcg cttccgcctg
    21301 cgtcttcgag ataacattca aaacttttga acgataagcg atgttcatta cgtttacgtt
    21361 ggcaggtgtc atattccgtg caagcatgtc tttagtatag aagtatttac ttttcacgtt
    21421 aaaaatccgc tttaactcat tcacgatttg cattttagga gatgtatacg cattctcgta
    21481 ctgccagact gcttgttctg taacacctaa catttcggag agctgttttc ttgaatatcc
    21541 atgcatgatc cgtagattgg tcaaattttc acctatgaac atgctgctcc ctccttattg
    21601 gactaacccg tcttgtttgt ctagttgtgt tgctcttctt ccaggatccc aatatcgaaa
    21661 gctgctgggt ccataatatc ttcactcatc tctggcgcga ctacttcgcg gtcttcctcc
    21721 gttaaatcag ctccagaaat aagacttgag aggtcttcta tcaggtaagc aatattatcc
    21781 tcaggattag gcaaataatg cattatttca gatatctgat atgcctcatc aagtgcatat
    21841 gtgagtatat ggaactcatt gtaggatgat ttaaagcttt cgagttcatc ttttacctga
    21901 ctctctaaaa ttagaaaaga aagttgttca ggtacccccc ttatcttcga ggattgctga
    21961 gtaggagaaa acaataaatc tttgttaatt tttgaaagtt catgaagata ggtacgacgc
    22021 ggacctttcc ctccgtaatt actaggtagc tttgcctgtg aaaaacattt ttcattgaaa
    22081 taggccgcgt tcttaataag aaaaagaatt ttagagtctc catggataaa ttggagatag
    22141 tcccacgtta atccagcttt cgatttttta tatgtaaaac cataatcaac gcattcttct
    22201 gcgatcttac tttcgataaa gttacccttg gtccaggcaa aagctgaact gatcttcatt
    22261 tttgcttttc gatctttacg atgctcaata taatcgcgat atccatctac gatagcatca
    22321 acaatcattt tgttgtgttc ggaattaaat ttgaatttat ccatatccat cgctccgatt
    22381 cataggtatg aagaatacct atattttaat cgaaattcgg acttaaggaa atgatttttt
    22441 ttgttttttt taaagttgga ctgtatattg aataaaatct ttatagtcat ttaggtttta
    22501 aaacgatgtt gcctttaaat tattctcatt cttcccgcag atcatccgtc tgttgacgag
    22561 agatgggcac actaacgctg gttagttagc aacaagactt ttttaattac cacatgttta
    22621 caacttattc tctgtaattg tgatcaatat gtgaactggg catagttctc attcccaaat
    22681 ccatactgaa tatatctgtt ggtaatggag gcgggaattg tggataaaag gatgaatctg
    22741 cttatgttca gcggcgatta tgataaggca atggcaggac tgattctggc aaatacggcg
    22801 cgggaattag atgtggacgt gacgatgttt tttgcgttct ggggattatc actggttcgt
    22861 gatcccgaga agatgacgct tgaggataag acgatctacg agaaactcat ggacttgatg
    22921 actcccaaag ggcctgaatc catgccgctg tcccatatga atttcagcgg tctgggcaag
    22981 ctgatgctga cggaaatgct ggaagacaat gaggcaccga agctgattca ttttctgaaa
    23041 ggagcgcgga agaaaaacgt caaattttat gcctgcaagc tatcagtcga aattatgggt
    23101 tttaaaccgg aagaatttat acctgaactg gaaattatcg aggccaaaac gtatctaaaa
    23161 gatgcgctcg aatccgatat gcagttgttt atataggata gacttgcgcc ttatccggcc
    23221 gttggatgag gcttttattg tgactaaatg atgacactcg cctatttttt ttaacccatt
    23281 cgggcctacc tacgtaccct aaaaagacag aacgacttgg gaggcgccgt atgctcatgg
    23341 ctcgaattgg aagcagtaat tgtaggtatc agccttctaa cgaggcttat ttccaaaggt
    23401 atcgcgaaag tacaatcgga tatcaccaga cctttgaatc tccatatggg caaaaaaagc
    23461 tgatttatgc ggattgggca gccagtggtc gtctgtatgg acccatagag tcgaaaatag
    23521 ctcatgaatt aggccctttt gtggcgaata cgcatacgga gtctaatttg acaggaactc
    23581 tgatgaccca agcctatgaa gaagcgaaac aaatcattaa gagccacgtt catgccaatg
    23641 aacatgatat catcctgttc gccgggtccg gtatgacagg tgcagtgaat aagcttcagc
    23701 ggctgttagg attgaaaata catgaaaaac taaaacatca ttaccctatc gctgaaaaag
    23761 aacgtcccgt tatcttcgtt acacatatgg agcatcattc caatcatatt tcctgggcag
    23821 aaaccattgg agacgttgta tgtcttcctc tgggtcccga cgggattgtc gatccaactc
    23881 aactcgaacg actactgctt caattccggc atcgccctat caagatcggc gcttttacag
    23941 cctgttccaa tgttacgggg tttgagccgc cgatttatca gctatcccgc aaaatgcatg
    24001 agcatggtgg cgtttgtttc gttgattttt cggcaagcgc accttatgcc gcgatcaaca
    24061 tgcatcccgc agagccgctt gaaagattgg atgctattgt attttctccc cacaaatttc
    24121 ttggcggtcc cggtacaagc ggcgttttaa ttatggattc gagactgtgc cttaattgtg
    24181 ctccagatca gcccggaggg ggtacagtta gctggaccaa tccttggggt ggatacgagt
    24241 ataaaaataa tactgaagcc cgtgaggatg gagggacgcc tgcctttcta caagccactc
    24301 gaaccgcgct ctgcattcgg ctaaaagaac agatgggaca gaagcgtctg ttggagcgca
    24361 aaaaggaact gacatcatta ttactaaaga gcttgagtac cataccaggg ctacacattt
    24421 taggaggaag cagccaagaa cgaatgggaa tcgtttcttt cgttgtcagc catattcact
    24481 ataacctgat tgtaaaacta ttgaatgatc ggtttggcat ccaggtccgg ggcggctgct
    24541 cttgtgcagg cccctacgga cattatttgc tgggcatcga cccacaaaca tctaaacaaa
    24601 tgacagacct gatccatgcg ggagacttat ctcgaaaacc gggctgggtg cgtctgtcgc
    24661 tccatcccat gatgacgaat caggaagtct cctatatcgc ctcttccata cgagcaatcg
    24721 tggaaaacat catgacctgg caaaaagatt atacctatca accagaatca aacgaatggc
    24781 gagctatgca tgaacataac aaaatagaca tcagcaaatg gttcaatttc agcgattagg
    24841 agacccctgt ccgttccctt ccttcaaaac tctcatagat tattctgtag gattactata
    24901 tgaggaaaga agtgacgaca aatgggtctc aattttcgca acagtaccaa tgcggctatc
    24961 tttgtggtct ttgcctatcc ggacttcagc tgtactcctg ttaactactc taaagcaggc
    25021 tggtaccaag ttaatcccgg acagactatc caggtgtgga gcggcttccc aggaggtaat
    25081 acgttctttt attacgctga agatgatttt ggacgcgaat ggcggggttc atatttcact
    25141 caagttcctg agaatgcctt caattggtgc tgggatacag gctgtaccac ttgtagaagc
    25201 gtgggactgc ggagaatcgc agttagtccg ttcgtcttcg actatactat caactttgta
    25261 acgagcagca gtcaaagaaa acctgcatca tccacactcc gcatgacatt gccttccaaa
    25321 gcaacccagg agaaacctat cttgcgcaga gttcctgcta aacctaagag actaaaacaa
    25381 gggaagcctc aattacagaa acgcatcacg cataaaaaac gaaccaaata aagaatgatc
    25441 tgatcagctc acataaagat tattttagaa ttaagaaagg agcgacctca cccccatggc
    25501 ctgctccttt ctcttttatc tatgaggtaa cccgcttatt tactctcgga ttcccacttg
    25561 gatatctctt cacgaacccg tggcgctacc tctgttccca atagctcaat tgctctcatg
    25621 acatcatcat gcggcatcgt accgacaggc acgtgcaaca gaaaacgtgt aatgcctacc
    25681 tgtttacgca gatgaatgat tttttgggca accgtgtcgg aatcgcctac atacaacgct
    25741 ccttcaaggc tgcgtgcggc atcaaagctg gaacgagtgt aaggacccca cccacgttca
    25801 cgccccagca cattcatgct ctgctgagtg gaagggaaga acttatccgc tgccagctca
    25861 gttgtctctg cgataaaacc atgggagtgt gatgcaaccg gaagcagcga tgcatcatga
    25921 ccggcatgcc tagcggcttt tttatacagt tccaccaacg gggcaaactg tacaggactc
    25981 cccccaataa tcgccagaac caacggcaat ccgagcaaac ctgcacgaac cacagattcc
    26041 tgattgcccc cactcccaat ccatacaggc aaagggtttt gaactggacg cggatataca
    26101 cccaaattgt tgattgccgg ccgatgtccg cctttccagg taactttctc ggattctcgt
    26161 attttcaata acagctccag cttttcatcg aataactcat cgtagttatc caaatcatac
    26221 ccaaataacg ggaacgattc gataaaagaa ccccggcctg ccataatctc agctcgtcca
    26281 ttcgaaattc cgtccagtgt agcaaaatcc tgaaacacac gcaccggatc atccgatgaa
    26341 agcaccgtaa ctgcactggt taaccgaatt cgttgggtct gtgccgctgc agcagcgagg
    26401 ataacagccg gagcagatgc cgcataatct ttacgatgat gctcccctac gccgtacaca
    26461 tccagcccta cctgatctgc aagtacaatc tcctcgacca cttcacgtat tcgttgtgcg
    26521 tgactaataa cctcacccgt ttggggatcc ggcgttgttt ctacaaatgt gcttatacct
    26581 atctccactt gttctacccc ctattttcat gcctcgttct catacgactg ctttcaaagc
    26641 caatcatttt aaaaaccgat atctttatat tgaacctttt ttgcatcttt ttcaagctct
    26701 cattttctga gtctgaaaat cagccaacgg aagtgtcaag attcgccgca ggaaaagaag
    26761 tctctttgtc gaatatggta tggaataaag aagattccca tccccacacc atgaatacaa
    26821 caaggaggca cttacattta tggcttttgt tattaataat ttaaaggata acagcaatgt
    26881 tgctatcact gaccaattag gcggatttac ggtactggaa tacataacag atttgagctg
    26941 cacctcggtt gcggctgcgc aagacaatta ctatatgagc aaaagtaaca tgcgccgcaa
    27001 gcagctcatg atcgaaatca ataatagtga gattatgatg aaggcgggag ccatgcaata
    27061 tactgtgggg agcatggaaa tgactaccgg tgtaaaaggc gtgggaggct taatgcgaaa
    27121 cttggtgtcc ggtgctgtaa ccgggacaag tgccattaag ccacactata aaggcacggg
    27181 taccattatg ctggagccta cctaccaata tatttggctt attgatgtcg acaatgatga
    27241 tattgccatc gaagacggct tgtttttggc ttgtgacacg acgctggaca tatccgtcgt
    27301 tgcacgtagt aatctttcct ctgccgcact gggcggagaa gggttattta atttaagcgc
    27361 ccgcggaaaa ggagttctgg cacttcaagc tccaatccct tccgaggaag cggtcgttat
    27421 agaattgcaa aatgatgtgc tgaaggtgga tggcaacttt gcccttatgt ggtccaatac
    27481 cttacagttc accgtcgaaa aatccggtaa aaccaaaatg ggctcggctg cttccggcga
    27541 agggctggta aatgtgtaca ggggaaccgg aaccgtatgg ttagcaccat tataaacata
    27601 agaaaggaga agccctcggc ttctcctttc ttacatttta attctttttt acaaactccg
    27661 attttagctt cattgctcca aaaccatcaa ttttgcagtc aatatcgtga tcgccatcca
    27721 ccagacggat gttttttact ttggtgccga tttttaagac ggatgagctt cccttcactt
    27781 taaggtcttt aatgaccgtt acagagtcac catccagtag gatgttacca ttcgcatctt
    27841 tgacgacctt tacatcttcg ctacttacag cttctgaatc ggtagaccac tcatgagcgc
    27901 attccgggca aatgaataga ctgcgatcct cataagtgta ctctgaatta cattcaggac
    27961 aatttggtaa actagacatg gtattatgta ctccattcat tttcaaattc tactgctttg
    28021 ctaagcttcc ttgatagacc aagcttgctc caagccttcc ttggagttcc ctacaagtat
    28081 attggataaa cattcacgat tccactcatc gatgaaacta atttgagtat tgtaccgata
    28141 cgtaagcgcc ctgcctctga aaatgcccag aggtgaacat gtaactaaaa cggatgcggc
    28201 cttctaggca gcatccgttt ttacggcacg ttaattatgc ttgggtttgc ttgatcagtt
    28261 ctctaattcc ttggctaagc ggcgtaaggg ggcgtttcaa cagcttctcg aaatcgttgc
    28321 ttacgacatc caaggctccc tcacgaatcg cttgttgaat accgaccaca atagggattg
    28381 caccttccgg gactcctgca ccgagcataa cctcggcata cgtagcatca tccacctgct
    28441 gtacaggaac gtctttgccc agaacctcag caagtaccgc tgcaaactct tcttgggtaa
    28501 tcggcttgcc ggagagctcg tatattgtat tctcatgccc ttcactagac aaaacatttg
    28561 cagctgcttg cgcataatct gcgcgggtag cccaacctac tttaccggat cccgccgagg
    28621 ttagccaagg tgcccctgcg agtacggatt gaatcgtgcc tgcctcattc tccagatacc
    28681 aattattacg caagaaggag taaggaatac ctgactcgcg aatgaactcc tccgtgatgc
    28741 gatgtacggg tgcaagaaat agagtgctgt cagcggcgtt ggcagcgcta gtataggcga
    28801 tgaagcctac tccagcacgt acagcagcat caacagccgc tttatgctga cggattctag
    28861 tatcattatc tccgtctgcg gatataatca gcagtcgatc tactccagca aacgcttgat
    28921 ccagcgtctc cggtttatca aaatcaccat gacgaatatc cacgccacga gaccgtaagt
    28981 tctctgcttt ttctggattt cttacactaa caataagatc gtttgtggag acagatgtaa
    29041 gcaacgtatc taccacgatg gaacccaatt gccccgttgc tcctgttaat gcgattttca
    29101 tatgaaatcc tccattcaga ttgtatttac ttttatatag taactaaaaa tataacgcat
    29161 gtctaatcta gagtctaaag gtctgctttt cgggtaagag ttggtacaac aaactctccc
    29221 cagagaaagg aacatgtata tgaaaaaagc tatggtcatt gtaaatccct cttccggcaa
    29281 agaggaatct ctccaacatg tcagaaacgt agaagaaatt ctacgtgatc aaggatacgt
    29341 tgttacggtt aaagaaacgg caaaggaact ggacgccacc cgtttttgcg ttaatgcgtg
    29401 tgaggaagct tgtgacctag tcatttccat cggtggagat ggcacacttc acgaaaccat
    29461 caacggtttc attgatcaag accatcgccc aagactgggg gtcatccccc ttgggacagt
    29521 caatgatttt gcccgtgcct tgcaaattcc gctaagtccc gagctggcga tccgtacact
    29581 gacttctgcc cgcgtgaaaa acgtagatat gggcctctta aacggccgaa tgtttgccaa
    29641 tgttgttgcc acaggttcgc ttgctgaatc gctatcagct gtatcatcag acgataaatc
    29701 catgtttggc acatttgcct acttcaaaga aggcatgaaa gagcttatcg gccatcctgc
    29761 ccactcactt atcgtccgct atgatgacaa aacctgggaa ggaaaatctc cactcttttt
    29821 ggctacgtta accaactca
//
