LOCUS       NZ_CP071875            23144 bp    DNA     circular CON 27-MAR-2024
DEFINITION  Paenibacillus polymyxa strain SF05 chromosome, complete genome.
ACCESSION   NZ_CP071875
VERSION     NZ_CP071875.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5459135)
  AUTHORS   Chen,B., Zhao,F. and Han,H.
  TITLE     The complete genome sequence of Paenibacillus polymyxa SF05, an
            antagonistic strain isolated from maize sheath
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5459135)
  AUTHORS   Chen,B., Zhao,F. and Han,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAR-2021) Institute of Maize and Featured Dryland
            Crops, Zhejiang Academy of Agricultural Sciences, Tangxi Village,
            Chengdong Sub-district, Dongyang, Jinhua, Zhejiang 322100, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. v3.6.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400.0x
            Sequencing Technology             :: Nanopore; Illumina PE150
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028751565.1-RS_2024_03_27
            Annotation Date                   :: 03/27/2024 02:05:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,074
            CDSs (total)                      :: 4,919
            Genes (coding)                    :: 4,764
            CDSs (with protein)               :: 4,764
            Genes (RNA)                       :: 155
            rRNAs                             :: 15, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 15, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 108
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 155
            CDSs (without protein)            :: 155
            Pseudo Genes (ambiguous residues) :: 0 of 155
            Pseudo Genes (frameshifted)       :: 76 of 155
            Pseudo Genes (incomplete)         :: 112 of 155
            Pseudo Genes (internal stop)      :: 26 of 155
            Pseudo Genes (multiple problems)  :: 50 of 155
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:54:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 620550
            Orig. end                         :: 643694
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP071875.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23144
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="2"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23144
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23144
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13144](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13144
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(1070..1498)
                     /locus_tag="J4I02_RS02830"
                     /old_locus_tag="J4I02_02810"
     CDS             complement(1070..1498)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308581.1"
                     /locus_tag="J4I02_RS02830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_02810"
                     /product="DUF3995 domain-containing protein"
                     /protein_id="WP_274483792.1"
                     /transl_table=11
                     /translation="MLELLTWAVGGILWVLSGIHLYWVFGGQKGAKAAIPSTGTDLLFE
                     PSKIGTLTVAILLALAAWFVLELGEVTQFLFFRSFHSYGAGLLSCVFILHSIGDFKWVG
                     FFKRKKGTVFAKWDTVLYSPLCFLLGTAILIIMFLRAA"
     gene            complement(1511..1666)
                     /locus_tag="J4I02_RS02835"
     CDS             complement(1511..1666)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J4I02_RS02835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_274483793.1"
                     /transl_table=11
                     /translation="MQPEKAFQRSWMLYHYYLGWYERHKQETLSDEAIQQHIHMIWTEW
                     ISNEFN"
     gene            complement(1673..1870)
                     /locus_tag="J4I02_RS02840"
     CDS             complement(1673..1870)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J4I02_RS02840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_274483794.1"
                     /transl_table=11
                     /translation="MIAASIIHAATDERIRELLTQMFGKTKRGDFLFYLRKLSLKDDSY
                     RSLLDEFEQMRMEFMKELLI"
     misc_feature    complement(2154..2171)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 24.09"
                     /tool="antismash"
     gene            2351..4264
                     /gene="thrS"
                     /locus_tag="J4I02_RS02845"
                     /old_locus_tag="J4I02_02820"
     CDS             2351..4264
                     /EC_number="6.1.1.3"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrS"
                     /gene_functions="other (smcogs) SMCOG1162: threonyl-tRNA
                     synthetase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369206.1"
                     /locus_tag="J4I02_RS02845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_02820"
                     /product="threonine--tRNA ligase"
                     /protein_id="WP_013308583.1"
                     /transl_table=11
                     /translation="MSIQVKLPDGAVREYEQGVTIADVAGSISSGLKKNAVAGKVNGKA
                     VDLNTVLDQNVDLEIITLDGADGLEIYRHSTAHLLAQALKRIYGEKNVKLGIGPVIDSG
                     FYYDIDIENPLSVDDLAKIEKEMTKIAQENLPITRRVVSREEATRIFGELEDPLKLELI
                     RDLPEEAEITIYDQGEFFDLCRGPHLPSTGRIKAFKLLSVAGAYWRGDSNNKMLQRIYG
                     TAFPKKAQLDEHLHLLEEAKKRDHRKLGKELELFMFSEEAPGMPFYLPKGMVVRTALED
                     YSRDIQRLHGYEEVRTPLMMNNRLWEQSGHYEHYKENMYFSEVDETTFALKPMNCPGHM
                     LVFKNELHSYRDLPIRIAEFGQVHRHELSGALNGMMRVRTFCQDDAHIFVTPGQIEQEI
                     TDVIKLINEMYSVFGFDFTVELSTRPDDFMGEPALWDQAEQALQNVLDHLGINYRINAG
                     DGAFYGPKIDFHILDALKRSWQCGTIQLDFQMPEKFDLTYVGEDNQKHRPVVIHRAIYG
                     SIDRFMGILTEHFTGAFPLWLAPVHAKLLPVSENYIETANEIQDALLKAGLRVEVDTRN
                     EKLGYKIREAQLEKVPYMFVIGENEKTTGTVAVRKRGEGDLGSLSIADIVEKISTEIRE
                     KQ"
     misc_feature    4269..4285
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 21.23"
                     /tool="antismash"
     misc_feature    4512..4526
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.34"
                     /tool="antismash"
     gene            4549..5232
                     /locus_tag="J4I02_RS02850"
                     /old_locus_tag="J4I02_02825"
     CDS             4549..5232
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.4"
                     /locus_tag="J4I02_RS02850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_02825"
                     /product="response regulator transcription factor"
                     /protein_id="WP_274483795.1"
                     /transl_table=11
                     /translation="MYKILIIESDEKLCNELVKSLTENNLAVEFTHSGQESLLRFSRGI
                     YMLIVLDVKLNDIDGFEVLQKIRNASCVPVLMLSAKKDVVENICSLKLGADDYMTRPFE
                     RNEFVARIQSLIRRHTVLNNVSALEKKLVFNSLEIDPNKRVVVIDGRNVELQAKQFDIL
                     FYLAQNCNRIYTKKQIYEEVWKREYMYDDNNIMSHISKIRKRIQKSSASIQNIKGVGYR
                     FVEGE"
     gene            5312..6010
                     /locus_tag="J4I02_RS02855"
                     /old_locus_tag="J4I02_02830"
     CDS             5312..6010
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728879.1"
                     /locus_tag="J4I02_RS02855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_02830"
                     /product="response regulator transcription factor"
                     /protein_id="WP_274485520.1"
                     /transl_table=11
                     /translation="MNHTILIIDDDKDLCKLLKKCVGMENINAVICHNGNDGLKSLLHT
                     DFQLIVLDIMMPEIDGFDTLAKIREISPVPVLMLTSKVENSDKVHGLRIGADDYMTKPF
                     DVEEFIARVLSLIRRYTMLNSSPAESLKKLTFQGLTIELETFIVLVNEKEVELPVKEFE
                     ILCYLAENQGKVLTKQQIYERVWQERYAYDDANIMGYISRLRKKIELDTNNPAYIQTIK
                     GMGYRFNRGV"
     gene            6013..6930
                     /locus_tag="J4I02_RS02860"
                     /old_locus_tag="J4I02_02835"
     CDS             6013..6930
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="J4I02_RS02860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_02835"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_274483796.1"
                     /transl_table=11
                     /translation="MELMLILVTSIVCAIAVWMSVKLRRIRRKLNEVYEILTDIAAGDK
                     DRKILAAPNDITSSICYKINEIVYDLHAQIIEFKRAEELNKQLMTSLSHDVRTPLTTLI
                     GYLDAVNKGIVVGDEREEFIEIARLKSHALKEYVDKLFEWSKLRSDEETFVVHNVELTE
                     MTRTILQDWLPVFESIPMKYDITIPEQQIMIQMDKNTYFRIINNLIQNVVDHSGASCIS
                     IHIAVQGTNVAIMVEDNGKGVLKQDLPFIFSRLYKMDGVRFHQGSGLGLSIVQQLVKKF
                     KGTITVQSEPNLKTEFRICLPLVK"
     gene            7068..7991
                     /locus_tag="J4I02_RS02865"
                     /old_locus_tag="J4I02_02840"
     CDS             7068..7991
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /locus_tag="J4I02_RS02865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_02840"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_274483797.1"
                     /transl_table=11
                     /translation="MNEYIIETVNLTKQFGEQKSVANLNIHVKKGRIYGLLGRNGAGKT
                     TTMKMLLNLTQPTTGEVRIFGKDIQTDGKKILPRIGSLIESPGFYPNLTGTENLKLFAD
                     LRGISSRNAVENTLEVVGLAFRDKKLYSQYSLGMKQRLAIALAVMHDPELLILDEPSNG
                     LDPIGIAEIREYIRNLCTQRGKTILISSHILSEISLLADDIGIIDHGVLLEEESLKELE
                     QKNNKYVHFIVSDASQAARLLERRFNTHNFHVENDRSIRLYETSLPISTITRFFIENGI
                     DLFEAHTCEDTLEDYFKRVTGGVGIA"
     gene            7984..8763
                     /locus_tag="J4I02_RS02870"
                     /old_locus_tag="J4I02_02845"
     CDS             7984..8763
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.4"
                     /locus_tag="J4I02_RS02870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_02845"
                     /product="ABC transporter permease"
                     /protein_id="WP_274483798.1"
                     /transl_table=11
                     /translation="MLRLVKCELTKLKRKKFVMFVILGAFLFPFLFTMLALKGSLGNVR
                     VFDKLFVGIIGYGQIWMLPLVLGIVATILFFMERDYDTLKNLRTIPISTLRIVTSKLIV
                     LFIFGFIFSTASAGSSIIGGLLLGGINDVLYKFEVGAITGLLLTAGTLPIVIAIVFFNR
                     SYIISIIIVLFYDVFNFALILGGFQSRIPIIKLLYGIFPSPIINRWHWNVFVSPSLYYY
                     SELAPFMLPLSQVVITIAIMAILSYIAIVQIYRKREV"
     gene            8768..9541
                     /locus_tag="J4I02_RS02875"
                     /old_locus_tag="J4I02_02850"
     CDS             8768..9541
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024091.4"
                     /locus_tag="J4I02_RS02875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_02850"
                     /product="ABC transporter permease"
                     /protein_id="WP_274483799.1"
                     /transl_table=11
                     /translation="MNMCVLVKTEIIKLKRYSIIWIGIAAMLLLVLLSRYMVTASNGTV
                     STFESFSNLVIWNNFSLFFPATITLMSGYIITRERVNDTLKNILTVPVSFRSLLIGKLI
                     TVGLIAIFLGVVSFGLTLFIFLLSHCSGLAAKVLVQSFFQMIGINVCVYLAVLPIIILT
                     SHSANGFLAGVGFAFFYGLVGAFATGHDLTSVYPIAAGLGIINYQGEGGSSPLCYLTLI
                     AICLISIVLIAVMGKRSKTPAPLTDKFGNKSLRKH"
     gene            9706..9897
                     /locus_tag="J4I02_RS02880"
                     /old_locus_tag="J4I02_02855"
     CDS             9706..9897
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="J4I02_RS02880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_02855"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_274483800.1"
                     /sec_met_domain="mature_ha (E-value: 7.4e-05, bitscore:
                     20.6, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNELRNPVSRGEFMHPAGNVMEELGEAELQNFAAGGGIPNHSGG
                     AICTLTHECAGTHWYSCC"
     CDS_motif       9706..9813
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MKNELRNPVSRGEFMHPAGNVMEELGEAELQNFAAG"
                     /locus_tag="J4I02_RS02880_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9814..9897
                     /prepeptide="core"
                     /locus_tag="J4I02_RS02880_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.70"
                     /molecular_weight="2686.0"
                     /monoisotopic_mass="2684.1"
                     /core_sequence="GGIPNHSGGAICTLTHECAGTHWYSCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKNELRNPVSRGEFMHPAGNVMEELGEAELQNFAAG"
                     /leader_location="[9705:9813](+)"
                     /alternative_weights="2704.0"
     misc_feature    9953..9966
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.42"
                     /tool="antismash"
     misc_feature    complement(9994..10008)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.62"
                     /tool="antismash"
     gene            10001..13144
                     /locus_tag="J4I02_RS02885"
                     /old_locus_tag="J4I02_02860"
     CDS             10001..13144
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="J4I02_RS02885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_02860"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_274483801.1"
                     /sec_met_domain="DUF4135 (E-value: 1.3e-100, bitscore:
                     335.4, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.5e-57, bitscore:
                     193.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKYSYITEREYQNAGNKMYNSNIYEYWEKIMGKGIVSDFEKN
                     YDLNLNTILSSDEYEVHDLTSWADIVALQKLYFNKHFINTNFSLDFDGKEVLFFNFYIP
                     FIKIGLFKLNEKVKGLIEQCVETDFYVNLLEQLNKISVGTLIFEMHLSKKNNELYGRNA
                     REEYLDYNNRVLSDQDYVTELMNIYPCLFRMIYEAIMNQVDNYSLVLSRLKKDHNLIVQ
                     DFCRGNEFKHITAFNSSMSDSHQKGKTVIILTLDNDVKIVYKPRNLKIDIAYHEFLMFV
                     SSSAKHTMKDYKIADCGEYGWEEFVSHTSCSDNEALNRYYYRFGILIFTHFILGSNDLH
                     KENIIAAGEHPVIIDAETLLDNKKEIPKDSARGIINNILRESVLYSGLLPQRHFIRKGG
                     GIDLSAAKGKENVEYPVAIPRIAAKGTSDMHFVYEHPKTKFTQNLPTINGDGYSISGFV
                     DQVISGFRDVCMFVLQNKQETLEKVNLFANLKVRHLVQDTQRYYLLLHTSYHPDFLQDA
                     KDRHLLLGTLFSNWKIIHNSCEITKMEIADMLNMDVPYFYIYTDKRSLFGNDDKEIKDY
                     FPKTSMECLNEKIANLSDADLEEQLRYIRISLTNLNDIEIVKEQNNFTTINFKPGELKD
                     KTLWLKAVLKIADELLEKCVLNEDKSDVNWIGISAVGKDDDTTWDIRPLNTYLYDGLTG
                     IAIFLNALNKLNPCHDYSVICNALKNALFSYTDEICDRSTGLDEEASGAFSGEGSLLYT
                     YEILYSITGEEAYLNYAKKHVAVVSEAIIGDTGFDICFGNAGAILALLNLYKLTNDQKY
                     IEEASKAGYVLLENQQQGERGVSWLGEGSENALAGFSHGISGIALALSKLGYETNNEDF
                     TGSALSGLQFENSLYDLEYQNWKDERVFFGEKSSDQKVYMTAWCHGAAGILLGRSKMYP
                     YCSSEQKQGILQDMKLAVNTTVASGLSHNDCLCHGNLGNTEILREYNKLFPDNTVEELI
                     HASRYWIVRKICNGESIFSREYLFGHKTPGFMTGLAGMGYSLLRDLDESLPCVLALDI"
     gene            13200..15323
                     /locus_tag="J4I02_RS02890"
                     /old_locus_tag="J4I02_02865"
     CDS             13200..15323
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="J4I02_RS02890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_02865"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_274483802.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.5e-26, bitscore:
                     90.9, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKRQVPLVRQLGTTDCGPACLAMLFRYYGHKVSIVDVKASIHIG
                     RNGMTLSMMKKIAEKHGLSFHAFRDYYDENNFIQHLPAIVCLKTNHYVVISKRTKKGYV
                     MLDPIEGKKKMSFSDIQEHCHTVLLCLKPKEGIKYASKAPKLEIHINKKKFIMAIFLTI
                     LTQALILIPPLVIQYIVNQIEADKDENMIIIINCTLVLGFIYFVLNWSKKRVVLLLQNE
                     IYKKTVTQMIKKLFKIDLSFFENHSSGDLASRFNSVSDIYGFFSGMLILTFIDLLTAVF
                     CGAVMLYQSFILFFLIAVITLVQLNITYVLNLKLKQKIQNYYADKSRLDGILVEILNNV
                     SQIRSMHFESILSSNVHKKYDDCLDLLKQKIQLSDLMESILTAINIVTPIIIYAIGGFL
                     IKNDQLTLGALIAFVTFSTYFINPFRTLSLVLPQISNLKETIIRLKEFLNYKTDEQTGE
                     ITIEHFESLELKNVAYAYTDGGENDIIDINIIIEKGEKIAIVGASGSGKTTITKLLLNV
                     FSRYSGEIILNDNNIKQIERESIDKLFGAVTQIPMAINNTIRNNIDMFGNLTDDQIYEL
                     LNLVELKNDVMGFPLKLNTFIGENGQNLSGGQKQRIAIARALASNPEIIILDEATSNLD
                     PLTEKKIFENLKNIEITQITVTHRLNAIQDSDRIYVVSNGEIIEHGTHDQLIKCRGNYY
                     ENILYNDRGLMSI"
     gene            15478..15603
                     /locus_tag="J4I02_RS02895"
     CDS             15478..15603
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="J4I02_RS02895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_274483803.1"
                     /transl_table=11
                     /translation="MNINLLPNELFLTCKRGEGDLGSLSIADIVEKISTEIREKQ"
     gene            complement(15762..16562)
                     /locus_tag="J4I02_RS02900"
                     /old_locus_tag="J4I02_02870"
     CDS             complement(15762..16562)
                     /GO_process="GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016819513.1"
                     /locus_tag="J4I02_RS02900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_02870"
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="WP_274483804.1"
                     /transl_table=11
                     /translation="MNEPDWKHLSAVPLPLQEFQLQLDQNSVDAKQLEEWRKIPVLYQL
                     ALEELKNKIKLIQTEWKLLDGFSPIEHIKTRIKEPHSIVEKVRRKGHEVTLDNILREIH
                     DIAGMRVVCAFVKDIYRLMDHLHTREDIRILEVKDYIAHPKPNGYQSLHVIVEIPLILF
                     EGTRWIKVEIQLRTLAMDFWASMEHILYYKFDKKVPEHVVNGLAEAARATYELDQKMLK
                     LRGEILSLSEEQDAEESPAKPSEESSMKTLSLPADHATSRPQTC"
     misc_feature    16618..16636
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 24.37"
                     /tool="antismash"
     misc_feature    complement(16622..16640)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 25.29"
                     /tool="antismash"
     misc_feature    16760..16773
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.6"
                     /tool="antismash"
     misc_feature    complement(16763..16779)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 26.67"
                     /tool="antismash"
     gene            16838..17299
                     /locus_tag="J4I02_RS02905"
                     /old_locus_tag="J4I02_02875"
     CDS             16838..17299
                     /EC_number="4.4.1.21"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005547758.1"
                     /locus_tag="J4I02_RS02905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_02875"
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="WP_029515967.1"
                     /transl_table=11
                     /translation="MAKVESFQLDHTIVKAPYVRAAGVEHDEKGSTVQKYDLRFLQPNE
                     DALPTAAVHTLEHLLATYLRDEIKGIIDISPMGCRTGFYLILWNEHEPEEIALALEKTL
                     KRILETTEVPAVTALECGNYKDHSLFSAQEYVKIVLEAGISRDPFERVL"
     gene            17305..18075
                     /locus_tag="J4I02_RS02910"
                     /old_locus_tag="J4I02_02880"
     CDS             17305..18075
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686029.1"
                     /locus_tag="J4I02_RS02910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_02880"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_250273228.1"
                     /transl_table=11
                     /translation="MISIDLSHQTAVVTGGKSGIGKGIVELFIQSGAKVISADISYEEP
                     YRVVNPQLVETQLDISKPDDIERWCDLLISEAGVPDILVNCAGTSTMDYVIDSELADWE
                     KVFSINSTGLYVTSKRFAKEMVAARKSGRIIQMASQAGKNGYRAMGGYCASKHAVLGLT
                     KVMAIELARQNILVNAVCPGIVETPMKHRERIEGGVIRGMTAQEIYEEDCSQVPLGRTA
                     EVEDVANVVLFLASPLSAYMTGQAINVTGGMTMH"
     gene            18105..18986
                     /locus_tag="J4I02_RS02915"
                     /old_locus_tag="J4I02_02885"
     CDS             18105..18986
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369211.1"
                     /locus_tag="J4I02_RS02915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_02885"
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_274483806.1"
                     /transl_table=11
                     /translation="MRKSFVLLLGISLLLVAAGCGNKSSDSNGSSAASGSETQKVVIGS
                     MGSDAQIWKHIAQSQAAKDAKLDIEVKEINGGIETNNATKEGEVDVNAFQSWAYLVSYN
                     KESKADLKAIATTYLEPMGIYSQKFKSINEVTDGALVALADNPANTARGLKLLEASGLI
                     KLKADFNDALGTVNDITSNPKNLKFELIDDKTGPRVIQDVGLVLIGNTIALEGGLNVLK
                     DSLFHEEISQATKNNINVLVTSSDKANDKGLQKLADLYHNEDTQKYIKDEFGGTKVEVK
                     EPVSYLEEQTTK"
     gene            complement(19027..19866)
                     /locus_tag="J4I02_RS02920"
                     /old_locus_tag="J4I02_02890"
     CDS             complement(19027..19866)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686031.1"
                     /locus_tag="J4I02_RS02920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_02890"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_274483808.1"
                     /transl_table=11
                     /translation="MIEYLPRSKQHTELYLTQFGIEECIPSHFFGPAIRDHYLLHYILD
                     GEGTFEVSGFSYRLQKGQWFLICPQVITYYQADVVNPWSYCWFGFDGALAETLLKQAGL
                     TMTRPILNFEGDHLIHQYLQRMNESSECPKARETRLTGLLCLMLSELIEFGPVTPPEQK
                     ESRAEIYVEKVKDFIEMNYAQKITIEHIANFIGLNRSYLCSLFKQQVNTSIQDYLVRYR
                     INKACEMMGNAELSIGDISRSVGYNDPLLFSKIFKKVKGLSPKHYRIETHTQTQVDY"
     gene            20105..22288
                     /locus_tag="J4I02_RS02925"
                     /old_locus_tag="J4I02_02895"
     CDS             20105..22288
                     /EC_number="3.2.1.22"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017428015.1"
                     /locus_tag="J4I02_RS02925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="J4I02_02895"
                     /product="alpha-galactosidase"
                     /protein_id="WP_274483810.1"
                     /transl_table=11
                     /translation="MGIIVQEQTGLFHLQSSGMSYIIQIVDGFPVHVYWGDRLKHREPM
                     ADLLLHTPATAGLDRLPQEYPQYGSGDFRNPAYQVELEDGTRITELKYIGYRITKGKPS
                     LTGLPAVYTENEDEADTLELELQDDFSGLKVVLLYTVFTDRNVIARSARLSNAGAKNLR
                     LLRALSASVDFSGKSDLEFMYLSGAWAREGNITRKSILQGETRIDSKRGMSSHQLNPFA
                     ALVTRGTTESYGEVFGFSLVYSGGFEAGAEIDSFGSTRFSIGVNSFDFSWLLSPGESFQ
                     TPEAVMVYSGQGLGEMSRTYHRLYRTRLCRGKYRDEERPILVNNWEATYFDFNADKLVS
                     IAKEGAELGIELFVLDDGWFGKRDSDNSSLGDWYEDRRKLPDGLADVANRINRLGLKFG
                     LWFEPEMISPDSELYREHPDWCLHVPGRRRSEARWQLVLDYTRKEVRDYIYDSLAAIFS
                     SAPVSYVKWDMNRCLTEIGSAALPPERQSETAHRYVLGLYELLERVTTEFPHILFESCS
                     SGGGRFDPGMLYYMPQVWTSDNTDAVERLKIQYGTSLVYPVSATGAHVSAVPNHQVGRI
                     TPLDFRGDVAMSGNFGYELDLTKFTDEEKETVKRQIAVYKQIRGLVQKGDLYRLKSPFE
                     DNESAWMFVSEDQEDAIVYYFQVMAVPNAPWRALRLDGLNPELEYEVKSGNSGQKSIHG
                     GDRLMKLGLPLLYRQKDYESGWFRLRALRSNKA"
ORIGIN
        1 ccttaactca aatcggttat gtggtgggat tgctatttat cgtaccgctc agcgacatta
       61 tcgaaaatcg acggcttatg gtcgtatcgc tcatcattac agtctgtgca ttggttgttg
      121 ccgcttttgc taccaatgcc ccgttgttcc tgaccgcatc cttgttcatt ggaattggat
      181 ctgtggtagc tcaaatactg gtgccgtacg ccacctattt agcatccgaa gagcagcgcg
      241 gccgcgttgt tgggaatgtc atgagcggac tcttgctggg cattatgttc gcacggccag
      301 tagcaagctt tatcaccagc atctgggggt ggcaagccgt atttattttg tcagccattg
      361 tcttgacgct gttgacgatt ctgctctcgc gagcccttcc agaacgcaag cctgtgccta
      421 cggtatctta cagtaaattg attttctcgt tgggtactct tttaaaacaa acgcctgcat
      481 tgcgtcgccg tgccctctat caagcctgtc tatttggtgc attcagccta ttttggactg
      541 ttgttccttt acgattggcg gatgatttcg gaatgtctca acaaggaatt gcattgtttg
      601 ctttagtagg cgtaggtggc gcagtagctg ctccgattgc cgggagattg gctgataaag
      661 gctggagtaa agttttaacc gggttagcta tgatcattgc cgccttgtct tttttgctca
      721 tctatctttt tcaaagtcat tcgacggttg cactcgtact tctctttatt tcagcgatta
      781 cactggatat ggctgtatcg ggaaatcttg tacttggaca gcgtgtgatc tactccttgg
      841 gaagtgaggc gagagggcgt ttgaacggat tattcatgtc tatttttttc ataggcggag
      901 cgattggatc atcattaggg ggttggtcgt atgcgttagg aggttggaat ttcagtgctc
      961 tgattggagt cgtcctgcca gtgctggcct tgctgtactt tttcactgag aaagaaacga
     1021 gtggagacgt gcgaaagaaa caaaccacct gatagaggtc agcctgaagc taggccgcac
     1081 gcaaaaacat aatgattaaa atggctgttc ccaagagaaa acaaaggggc gagtagagca
     1141 cagtgtccca ctttgcaaaa acagttcctt tctttctctt gaaaaaccct acccatttga
     1201 aatcccctat agaatgtaaa ataaatacgc acgacaacaa gcctgcaccg taggaatgaa
     1261 aagacctgaa aaataggaat tgtgtaactt cacctagttc tagtacgaac caagcggcta
     1321 aagctagtaa aatggcaacg gtcaatgtcc ctattttgga gggctcaaag agcaaatccg
     1381 ttcccgtgct tgggattgct gccttagcgc ctttttgtcc gccaaacacc caatatagat
     1441 gtatgccgct tagtacccat agaattccgc caactgccca tgtaagtaac tccaacatgt
     1501 ggcatcctcc ttaattgaat tcattcgaaa tccactctgt ccaaatcatg tggatatgct
     1561 gttgaatggc ttcgtcactt aatgtctctt gcttgtgacg ctcataccag cctaagtagt
     1621 aatgatacaa catccatgat ctctgaaagg ctttctctgg ctgcattccc ttctatatta
     1681 aaagctcttt cataaactcc attctcatct gttcaaattc atcgagcaag gaacggtaac
     1741 tatcatcctt caatgacagc ttgcgcagat aaaacagaaa atctcctcgt ttcgtcttcc
     1801 cgaacatctg ggttaacaac tctctgatcc gctcatctgt ggcagcatgg atgatggacg
     1861 ctgcaatcac ctgttgtgtc gtctgttcct tccatgtctt ttttagagct gcgtaaatat
     1921 ggatacataa acgcccactt gaaatacctg cgaatttgat ctataatgct gtagcatata
     1981 gtgatattca aggcattgac caaagacatg atttccttga agggccgttc agagagaaaa
     2041 gacgaggctg agagcttttc cggcaaccgc atgtgaagtt acccctttgt agccgtgacg
     2101 ttgaacatgt agctgtgcaa tctggcagta acatcagtaa gcgcctaccg ctttatcccc
     2161 gttaacggat accaatggag ggtcacgcat gtcgtgcatg ggcatgttcc gatgaacata
     2221 aatgtacgca caggagcggg ccgaactagg gtggaaccac gagctgaacg cactcgtccc
     2281 ttgagggaga gaggcgtttt tttgcgttca attttgatat agaacacaat ttgaaatgga
     2341 ggctttaatc gtgagtattc aagtgaaatt gccggatgga gccgtacgcg agtacgagca
     2401 gggcgtaacg atcgccgacg tggcgggttc gatcagctcc gggctaaaaa agaacgccgt
     2461 agcaggtaaa gtgaacggga aggctgtaga tctgaacacc gttttggatc agaacgttga
     2521 ccttgaaatc attacgctgg acggtgcaga cggtctggaa atttatcgcc acagtacagc
     2581 tcatttgctc gctcaggcgc tcaaacgcat ttacggtgag aaaaacgtga agctgggtat
     2641 cggtccggtc atcgacagcg gcttctacta tgacattgat atcgaaaacc cattgtccgt
     2701 tgacgacttg gccaagatcg agaaggaaat gacgaagatc gcacaggaaa atctgccgat
     2761 tacacgtcgt gtggtcagcc gcgaggaagc cactcgtatt tttggtgaat tggaagatcc
     2821 actgaagctg gaactgattc gtgatttgcc ggaagaagcg gaaattacta tttacgatca
     2881 aggcgaattt tttgacctgt gtcgtggccc gcacttgcca tctactggcc gcatcaaagc
     2941 ttttaaactg ttgagtgtag cgggcgcata ctggagaggc gattccaaca acaagatgct
     3001 gcaacgtatc tacggaacag cattccctaa aaaagcacaa ctggatgagc acctgcattt
     3061 gctggaagaa gcgaaaaaac gcgaccatcg caagttgggt aaagagctgg aactgttcat
     3121 gttctccgaa gaagcaccgg gcatgccgtt ctacctgcct aaaggtatgg ttgtccgcac
     3181 tgcattggaa gattactccc gtgacattca acgtctgcat ggctatgagg aagtacgtac
     3241 cccgctgatg atgaacaacc gtctgtggga acaatcggga cactatgagc attacaagga
     3301 aaacatgtac ttctccgaag tggatgaaac tacatttgct ctgaaaccga tgaactgccc
     3361 agggcatatg cttgtgttta aaaatgagct tcattcttat cgcgatctgc caattcgtat
     3421 agccgaattt ggacaagtgc atcgccatga gctgtccggc gcgttgaacg gtatgatgcg
     3481 tgttcgtaca ttctgtcagg atgatgcgca tattttcgtc acaccaggtc agattgaaca
     3541 agagattaca gacgtaatta agctgattaa cgaaatgtat agtgtgtttg gctttgactt
     3601 cacagtggaa ttgtccacac gtccagatga ctttatgggc gagccagcgc tgtgggatca
     3661 agcggaacaa gctctgcaaa acgtgctaga tcacttgggc atcaactacc gtattaatgc
     3721 gggggatgga gcattttacg gtccgaaaat tgacttccac attcttgatg cgctcaaacg
     3781 cagctggcag tgcggaacga tccaattgga cttccaaatg cctgaaaaat tcgacctcac
     3841 ttatgtgggc gaggacaacc agaagcaccg tccagtcgtt attcaccgtg ctatctatgg
     3901 ttcgattgac cgcttcatgg gcatcctgac tgagcatttt accggtgcat tcccattgtg
     3961 gttggctcct gttcatgcga agctgttgcc agtatccgag aactatatcg agactgctaa
     4021 tgagatacag gatgcgttgc tgaaagcagg tctgcgcgtc gaagtggata ctcgcaatga
     4081 gaagcttggt tataaaatcc gcgaggcgca attggagaag gttccatata tgttcgttat
     4141 cggggaaaat gaaaaaacaa ccggtactgt agcggttcgt aaacgcggcg aaggcgatct
     4201 gggatcactc agcattgcgg acatcgtaga gaaaatcagc acagaaattc gcgagaagca
     4261 gtaatatttg attaagaaat gagcaaaaaa gccatcaaaa ccatgatgaa cgtggttttg
     4321 atggctcttt ttttgtacat tacagaatgc ataggtttta gcgaagctga gccaagcaga
     4381 agctctgtta cacttggttt gagaatccgt catatgtata tgaattgtgt actgattgta
     4441 ttgcaattat gtattataat ggaatacata gaatcaaaat gacttattta caattttatg
     4501 tttttcgtat gtgacactca tttttaaggg agtaggtgaa ttcgacaaat gtataaaatt
     4561 cttattattg aaagtgatga gaagttgtgt aatgagctag ttaaatcttt aactgaaaat
     4621 aatctagctg tggaattcac acattcggga caagaaagtt tattaagatt ttctagaggt
     4681 atatatatgt taattgtgtt ggacgttaag ctaaatgata tagacggatt tgaggtatta
     4741 caaaaaataa gaaatgctag ttgcgtacct gttttgatgt taagtgctaa aaaagatgtg
     4801 gttgaaaata tctgttcatt aaagctaggg gccgatgatt atatgaccag gccctttgaa
     4861 agaaatgaat tcgttgcacg gatccaatct ttaattagac gtcataccgt gctaaacaat
     4921 gtatccgcgc ttgaaaaaaa attagtcttt aattcgctag aaatagatcc taataaacga
     4981 gttgttgtta tagatgggag aaatgttgaa ttgcaagcca agcaatttga tattttattc
     5041 tatttggccc aaaattgtaa tcgtatttac actaaaaaac aaatatatga agaagtatgg
     5101 aaaagagaat acatgtacga tgataataat atcatgtctc atattagtaa aattcgcaaa
     5161 cgaattcaaa agagttcagc gagtatacaa aatattaaag gagtaggtta ccgttttgtt
     5221 gaaggtgaat aacaacgaat cacatgtctg ttaataactg ctgtacacaa caataaggag
     5281 tgagtgaatg atgggggatc aggttggaga aatgaatcat acaatcctaa ttattgatga
     5341 tgataaggat ctgtgtaaac tgctgaaaaa atgtgttggc atggaaaaca taaacgctgt
     5401 aatctgccat aacggcaatg atggactgaa atcactccta catacagatt ttcaattgat
     5461 tgtgcttgac atcatgatgc cagaaataga cgggtttgat acacttgcaa aaattagaga
     5521 gatcagcccg gttcccgtgc tcatgttgac ttctaaagtg gaaaatagcg ataaagtgca
     5581 tggactgcga ataggcgctg acgattatat gaccaagcct tttgatgtgg aggaatttat
     5641 cgcccgagtc ctgtcattga ttcgcaggta tactatgctt aattcttctc ccgcagagag
     5701 cttaaagaag ctgacttttc aaggacttac tattgaatta gagaccttca tcgtattggt
     5761 gaatgaaaaa gaggtagaac ttccggtcaa agagtttgag attttgtgct atcttgctga
     5821 gaaccaaggg aaagtcctta cgaagcagca gatttatgaa cgggtatggc aagaacgata
     5881 cgcatatgat gatgccaata ttatgggata tatcagcagg ttgaggaaga aaattgaatt
     5941 ggacaccaat aatccagcct atattcagac cataaaaggt atgggctatc ggttcaatcg
     6001 tggagtgtag aaatggaatt aatgttgatt cttgtcacaa gtatagtatg tgccattgcc
     6061 gtgtggatgt ctgtcaaact tcgtcgtata aggagaaaat taaatgaagt ctacgaaata
     6121 ttgactgata ttgcagcggg ggacaaagac cgtaaaattc tcgctgcacc aaatgatatc
     6181 acttcctcaa tctgttataa aattaatgag attgtatatg atcttcatgc tcagatcatt
     6241 gaatttaaac gggcagaaga gctgaacaag caattgatga ccagtctgtc ccatgacgtt
     6301 cgcacaccct taacgacgct tattggttac ttggatgcag tgaataaagg gatcgttgta
     6361 ggggatgaaa gggaagagtt catcgaaata gcacgtctga aatcacatgc tttgaaagag
     6421 tacgtagata aactttttga atggtccaag cttcgctcgg atgaagaaac cttcgtggtg
     6481 cataacgtgg aactaacaga aatgacccga actattttgc aagattggtt acctgtattt
     6541 gaaagtattc ctatgaaata tgacattacc attccggaac aacagattat gattcaaatg
     6601 gataagaaca cttatttccg catcataaac aatttgattc aaaatgtagt agatcatagc
     6661 ggagccagtt gtatttcaat tcatattgct gtacaaggca caaatgtagc tatcatggtt
     6721 gaagataatg gtaaaggagt tttaaaacag gatttgccgt ttatattttc tcggctgtac
     6781 aaaatggatg gggtacgatt ccatcaaggt agtgggttgg ggctttctat cgtacaacaa
     6841 ctcgtaaaaa agttcaaggg aacaattacc gttcaaagtg aaccgaatct aaaaaccgag
     6901 tttagaatct gtcttccttt ggtaaagtaa atgaatgctc gtttcccaaa aggtccttac
     6961 ttgtgtaggg acttttcatt ttaaattcta ggttagtttt atgtttaaat ggggcgtgga
     7021 atattaaaat cattgtataa ccttcaacat ttaaaggaga gaaatccatg aacgagtata
     7081 ttattgaaac ggttaattta accaaacaat ttggagaaca gaaaagcgtg gccaatctca
     7141 atatccatgt gaaaaagggg aggatttatg gattattggg ccggaatggc gctggaaaaa
     7201 cgacaacgat gaagatgctg cttaatctta cacagcctac aactggtgag gttcgcatct
     7261 tcggtaaaga tattcagact gacggaaaaa aaatacttcc tcgcattggc agcttgattg
     7321 aatcgccggg cttttatccc aatttgacgg ggacggaaaa cctgaagctt tttgcggatc
     7381 tgcgggggat ttcaagccgt aatgctgttg aaaacacgct ggaagtggtg gggcttgcat
     7441 ttcgggataa aaaattatac tcgcaatatt cccttggcat gaagcaacgt ctggctatcg
     7501 cgttagcggt catgcacgat cctgagctac tgatactgga tgagccaagc aatggacttg
     7561 atcccatcgg tattgctgag atccgtgaat atatacggaa tctatgtaca caaagaggga
     7621 agacgatttt aatctctagc catattttat ctgaaatttc tttactggca gatgatattg
     7681 gaattattga tcacggtgtg cttttggaag aagaaagttt gaaagaatta gaacagaaaa
     7741 ataataaata tgtccacttt attgtctctg atgcatcaca agcggctcgt ttgctggaaa
     7801 ggagatttaa tacacataat tttcatgtgg agaatgatcg aagtatccgc ctgtacgaaa
     7861 catcattgcc gatttcgacc attacccgtt tttttataga aaatggaata gatttgttcg
     7921 aggcacatac ctgtgaggat acacttgaag attactttaa aagagtcacc ggaggtgtgg
     7981 gtattgctta gattggtgaa gtgtgaactc acaaagttaa aacggaaaaa gtttgtgatg
     8041 tttgttattt tgggagcctt cttatttccg tttcttttta ctatgctggc attaaagggc
     8101 agtcttggta acgtgagagt gtttgacaaa ttatttgttg ggattatagg ttacggacaa
     8161 atttggatgc ttccccttgt tttgggcatc gtggcgacaa tactattttt tatggaaagg
     8221 gactatgata ccttgaaaaa tctaaggacg attcccataa gcactcttcg aattgttacc
     8281 tctaaactta ttgtattgtt tatctttgga tttatttttt ctactgcatc tgcaggctcc
     8341 tcaatcattg gtggattgct tttaggtgga attaatgatg tactttataa gtttgaagtg
     8401 ggggcaataa caggattgtt attaacagcg ggaacacttc caatcgtcat tgccattgtt
     8461 ttttttaatc gttcttatat tatttcgatt atcattgtgt tattttatga tgtttttaat
     8521 tttgctttga tattaggggg gttccagtct agaattccca ttataaagtt gctatacggt
     8581 atattccctt ctccaattat taatcgttgg cattggaatg tattcgtatc gccatcgctg
     8641 tattattact ctgaacttgc acctttcatg ttgcccttgt ctcaggtcgt aatcaccatt
     8701 gcgatcatgg ctattttgtc ctatatcgcc atagttcaga tttataggaa acgggaggtg
     8761 tgaacaaatg aacatgtgcg tattggtgaa aacagaaatc atcaaattaa agcgctactc
     8821 tatcatttgg atcgggattg cagctatgct gttgctcgtt ttattgtcac gttatatggt
     8881 gactgcctct aacggaacag tatctacttt tgagagcttt tcaaatttgg tcatctggaa
     8941 taatttcagc ttgttttttc ctgccacaat aacattaatg tcaggttata ttattactag
     9001 ggaacgggtg aatgatacat taaaaaatat tttgactgtc cctgtatctt tccgtagcct
     9061 gctgattgga aaattgatta cagtaggtct gatcgcgatt tttcttggag ttgttagctt
     9121 tggacttaca ttgtttatat ttctattgag ccattgttcg ggattagctg ccaaagtgct
     9181 ggttcaatct ttttttcaaa tgataggtat aaacgtatgt gtatatttag cggtcttgcc
     9241 tataattata ttgacaagtc atagtgcaaa cggatttttg gcgggagtcg gctttgcgtt
     9301 tttctatggc cttgtagggg cttttgctac tggacatgac cttactagtg tgtatccgat
     9361 tgcagcaggg ctaggtataa taaactatca aggagaaggg ggttcttcgc ctctttgtta
     9421 tttaactttg atcgccattt gccttatttc tattgttcta atcgcagtaa tggggaaaag
     9481 aagtaagaca cctgcaccgt tgacagacaa gtttggcaat aaatcattaa gaaagcatta
     9541 agcagtttaa ctaaggactc tccttctgga gagtctattt tattttcaag gttaaggcaa
     9601 ggttggtatg ataagatgtt ttctgttgga agggttagtg gattttgata ggaaagtagc
     9661 aatccgaatc cgcctcaata aaatttatgt aaaggagaat gagctatgaa aaatgaattg
     9721 agaaatccag ttagtagagg agaatttatg cacccggcag gtaatgttat ggaggaactt
     9781 ggtgaagcag aattgcaaaa ctttgcagca ggtggaggaa ttccaaatca ttctggtgga
     9841 gcgatttgta cgcttacaca cgaatgtgcg ggaactcact ggtactcctg ttgctaaatg
     9901 tagctgacaa ctaaaaggac ataaagattt ggaattttat taattctatc tattgaggcg
     9961 gatccagatt gttactttag aaaaaaagag gtgtttgcag atggagaact taaaatactc
    10021 ttatataact gaaagagagt accagaatgc agggaataaa atgtataatt ctaatatata
    10081 tgaatattgg gaaaaaataa tgggaaaagg aattgttagt gattttgaaa aaaactatga
    10141 cttgaactta aatacaattc tatcgtctga tgagtatgaa gttcatgatc ttacttcatg
    10201 ggctgatatc gttgctttgc aaaaactgta tttcaataaa cattttataa atactaactt
    10261 ttcattggac tttgatggga aagaagtttt attctttaac ttttatatcc cgtttattaa
    10321 aatcgggttg tttaaattaa atgagaaggt aaagggttta atagaacaat gtgtggaaac
    10381 cgatttctac gtcaatttgc ttgaacaatt aaataaaatt tccgtcggca ccttgatttt
    10441 tgaaatgcat ttatcaaaaa aaaataatga actatacgga agaaatgcac gagaagaata
    10501 tttggattat aacaacagag ttttgagtga tcaagattat gttacagagt taatgaatat
    10561 atatccatgt ttgtttagga tgatttatga ggccataatg aatcaagtgg acaattattc
    10621 tcttgtgcta agtagattaa aaaaagatca caacttaatt gtgcaggatt tttgcagagg
    10681 gaatgagttt aaacatatta cagcttttaa ttcaagcatg tctgactcgc accaaaaagg
    10741 aaaaacagtc attatattaa ctctcgataa tgatgtgaaa atcgtttata agccccgtaa
    10801 cttgaagata gatatagcgt atcatgaatt tttgatgttt gtatcctcgt ctgccaagca
    10861 taccatgaaa gattacaaaa tagcggattg tggtgaatat ggctgggaag aatttgttag
    10921 ccatacgtcg tgtagtgata acgaggcgtt aaaccgatat tattatcggt ttgggatatt
    10981 gattttcact catttcatct taggctcaaa tgatttacat aaggaaaata ttatagctgc
    11041 aggagaacat cctgttatta ttgatgccga gactcttttg gataataaaa aagagattcc
    11101 gaaggattcc gcacgaggga taattaacaa tatactgcga gaatctgttc tgtactcagg
    11161 cttattacca caacggcatt tcatacgtaa aggaggggga attgatctta gtgcggcaaa
    11221 aggaaaagaa aatgtagaat accctgtcgc aataccaaga attgcagcta aggggacaag
    11281 tgatatgcac ttcgtttatg aacatcctaa aacaaaattc actcagaatc ttcctacaat
    11341 taatggtgat ggttattcta tttcaggctt tgtcgatcag gtcatttctg gatttaggga
    11401 tgtatgtatg ttcgtcttgc aaaacaaaca agagacatta gagaaagtaa acctgtttgc
    11461 taatctaaaa gtcagacatc ttgtacaaga cacgcaaaga tactatttat tgttacatac
    11521 ctcttatcat cccgattttc ttcaagatgc taaggatcgc catctgctac tgggcacatt
    11581 gtttagtaac tggaagatta tccacaactc atgtgaaatt acaaaaatgg aaatagcgga
    11641 tatgctaaat atggacgtac cctattttta tatatataca gataaaaggt ccttgtttgg
    11701 gaatgacgac aaagaaatta aggattattt ccccaaaacg agtatggaat gtttaaatga
    11761 aaagatagca aacttgagtg acgccgattt agaggaacaa ctcagataca ttcgaataag
    11821 cttaacaaac ctaaatgata tagagatagt caaagagcaa aataatttta cgacgataaa
    11881 ttttaagcct ggtgaactaa aagataaaac gctatggtta aaagccgttt tgaaaattgc
    11941 ggatgaactt cttgagaaat gtgtgctgaa tgaagataag agtgatgtca attggattgg
    12001 tatttcagcg gttggtaaag acgacgatac gacttgggat attcgtcctt taaataccta
    12061 tttgtatgac ggcttaacag gcattgctat ttttttaaat gctctaaata agttgaatcc
    12121 ttgtcatgat tacagtgtaa tctgtaatgc attaaaaaac gcattgtttt cgtacacgga
    12181 tgagatttgc gatcggagca cgggattaga cgaggaagca agcggtgcct tttccggaga
    12241 aggatcattg ttgtatactt atgagatttt atattcaata acaggtgaag aggcatattt
    12301 aaactatgct aaaaaacacg ttgctgtagt gagtgaggcc attataggag atacgggatt
    12361 tgatatttgt tttggtaatg ccggagcaat cctggcattg ttgaatctat acaagttaac
    12421 gaatgatcaa aaatatattg aagaggcaag taaagccggg tatgttttac ttgaaaacca
    12481 gcaacaaggt gaacggggtg tgagctggtt aggagaggga agtgagaacg ccttagctgg
    12541 tttttcacac ggcatttccg gtattgcgct tgctttgagc aagctagggt acgaaacgaa
    12601 taatgaagat tttactggat cggcgttatc tggactacaa tttgaaaatt cactttatga
    12661 tctggagtat caaaactgga aggatgaaag agttttcttt ggagaaaaga gctctgacca
    12721 gaaagtttat atgacagcgt ggtgtcatgg agcggccggg atacttctgg gaagaagtaa
    12781 aatgtatcct tattgttcct cagaacagaa acaggggata ctgcaggata tgaaactggc
    12841 tgtgaatact accgtagcct ctggtcttag ccataatgat tgtttatgcc atgggaatct
    12901 gggaaatact gaaattttac gagaatataa taaattattt cctgataata cagttgaaga
    12961 attaatccat gcaagtaggt attggattgt taggaaaata tgcaacggag agagtatttt
    13021 tagtagagag tatctatttg gacataaaac accgggattt atgacgggat tagctggtat
    13081 ggggtattct ttgcttaggg atttagatga atccctgcca tgtgtgttag ctttggatat
    13141 ataacaatcg aaatctgtta cgtattttag tgaacctttg atgaaagaag gtataggtat
    13201 tgcgtaagag acaagttcct ttagttcgcc agctcggtac tacggattgt ggaccggcct
    13261 gtttagctat gctttttcga tattacggac ataaagttag tattgttgat gtaaaagctt
    13321 ctattcatat aggacgaaat ggtatgacgt taagtatgat gaagaaaatc gccgaaaagc
    13381 atggattatc tttccatgct tttcgggatt actacgatga aaataatttc attcaacatc
    13441 tgccggctat agtatgctta aaaaccaatc attatgtcgt tatttctaaa agaacaaaaa
    13501 aaggctatgt catgctggat ccgattgaag ggaaaaaaaa gatgagtttc tctgatatcc
    13561 aagaacattg tcataccgtc cttttatgtt taaaacctaa agagggaata aaatatgcta
    13621 gcaaggcacc aaaattagaa atacatatta ataaaaagaa atttataatg gccatatttc
    13681 ttaccatatt gacacaagcc ctgattttaa ttccgcctct ggtgatccaa tatattgtga
    13741 atcagatcga agcggataaa gatgaaaaca tgataattat catcaattgc actttggttt
    13801 taggttttat atattttgta ttaaactggt cgaaaaaaag agttgtttta ttgttgcaaa
    13861 atgaaatata taaaaaaaca gttacacaga tgatcaagaa attatttaaa attgatttat
    13921 ctttttttga aaatcattcc tcaggcgatt tggctagtcg cttcaatagt gtaagtgaca
    13981 tttatggttt tttctcagga atgttaatcc taacattcat tgatttatta acagcagtct
    14041 tctgcggggc tgtgatgttg tatcaatcat ttattttatt ttttttgatt gcagtaatta
    14101 cgctagtcca actgaatatt acgtatgttc tcaatttaaa attaaaacaa aagatccaaa
    14161 attattatgc ggataaaagt cgtttagatg gcattttggt cgaaatatta aacaatgttt
    14221 cacaaataag aagtatgcat tttgagagta ttctcagcag caatgttcat aagaagtatg
    14281 atgactgttt agacttatta aagcaaaaaa tacagttgtc tgatctcatg gaatctattc
    14341 ttactgctat caatatagtc actcctatta ttatatatgc gatcggtggc tttttaatta
    14401 aaaatgatca gcttactcta ggagccctta ttgcatttgt gaccttttca acttatttca
    14461 taaacccatt cagaacactt tcgttggtcc tacctcaaat tagcaattta aaagaaacga
    14521 ttatacgatt aaaggagttt ttgaactata aaacggatga acagactggt gaaataacga
    14581 ttgaacattt tgaaagcttg gagctaaaaa atgtagcata cgcttataca gatggtgggg
    14641 aaaatgatat tattgacatt aatataatta ttgaaaaggg agaaaaaatt gcaattgttg
    14701 gagcttcagg aagtgggaaa acaacgatta ccaaattact actaaacgta ttttcacgct
    14761 attctggaga aattattctc aatgataata acattaagca aatagaacga gaatccattg
    14821 ataagttatt tggtgctgtt acacaaatac ctatggctat caataacact ataagaaata
    14881 atattgatat gttcggaaac ttaaccgatg accaaattta tgaattactc aatctggttg
    14941 aactaaaaaa cgatgtaatg ggttttccat taaagttaaa tacttttatt ggtgaaaatg
    15001 gtcagaactt atctggtggt caaaagcaaa gaattgctat agcgcgtgct ctggcttcca
    15061 atccagagat cataattctc gacgaagcta caagtaatct ggacccgtta acagaaaaaa
    15121 agatttttga aaatttgaaa aacattgaaa ttactcagat aacggtaact catagattaa
    15181 atgctattca agattcagat cgaatctatg ttgtgtctaa tggcgagatt atcgaacatg
    15241 gaacccatga tcaattaatt aaatgtagag ggaattacta cgaaaatatt ttgtataatg
    15301 atcgaggcct aatgagtata tagttaaacc gtctccacta cgtcagctta agtagcgata
    15361 accgctgttt tttcgttgag aaagcaagat gggtgtcaga acaattgatg agtgcgatgc
    15421 gatgatttat taagaacagc ctcacgtgct gattagtaaa gcggttggaa ggtacccgtg
    15481 aacatcaatt tattgcctaa tgaactgttt cttacatgca aacgcggcga aggcgatctg
    15541 ggatcactca gcattgcgga catcgtagag aaaatcagca cagaaattcg cgagaagcag
    15601 taatatttga ttaagaaatg agcaaaaaag ccatcaaaac catgatgaac gtggttttga
    15661 tggctcttta tttataccca atacataaga atccagcgta agactgaacc aacgtttttg
    15721 cagcctcaac tgaatgctta agttatcttg tacacaaata cttagcaggt ttgtggccgt
    15781 gaagtggcgt gatctgcagg gagggagagt gtcttcatgg acgactcttc ggatggtttc
    15841 gccggggatt cttccgcatc ctgttcctcg ctaagcgata aaatttcgcc gcgcaacttc
    15901 agcattttct gatccagctc gtaagttgca cgtgcagctt cggccaatcc attaacgaca
    15961 tgttcaggca ctttcttatc gaacttatag tacaaaatat gctccatact ggcccagaaa
    16021 tccatagcca atgtgcgcaa ttgaatttca accttgatcc agcgtgtgcc ctcaaacagg
    16081 atcagtggaa tttccacaat gacatgtagg ctctgatagc cgttgggctt aggatgggct
    16141 atatagtcct tgacctccag aatacgaatg tcttcccgtg tgtgaagatg atccatcaga
    16201 cgataaatat ctttcacaaa agcgcatacc acgcgcattc ccgcgatatc atgaatttca
    16261 cgcaatatat tgtccaaggt gacttcatgc cctttgcgcc gaaccttttc cacgatgctg
    16321 tggggctctt tgatccgggt tttaatatgc tcaatcgggc taaaaccgtc taacagcttc
    16381 cattccgtct ggatcagctt aattttattc tttaattcct ccagagccag ctgataaagg
    16441 acgggaatct ttctccactc ctctagttgc ttggcgtcga cactgttttg atccagctgt
    16501 agctgaaatt cctgcaaggg taatgggaca gcactcaggt gcttccaatc cggttcattc
    16561 acagagcatt ctcctaaatg aggctatgat gtcctcgatc tttttcgtaa aaatgcatta
    16621 tcgtatacat tgtacactat gtcaaaacct acaggcaaag gagagacaat caaagaaaaa
    16681 aagaaatacg acaagaatta tggtggtaaa accgagtaat ccgatgtata attacaaaaa
    16741 tgctgatttg gagcatttaa ttctttaaaa aaattacaaa tgaagagtat ccatcattag
    16801 attaaaaata taaattacag aaaagaggaa aagaaaaatg gcaaaagtag aaagttttca
    16861 attagatcac acgattgtaa aggctcctta tgtaagagca gcgggagtag agcatgacga
    16921 aaaaggaagc acagtacaaa agtatgactt gagattttta caacccaatg aagatgcact
    16981 tccgacagca gctgtacata cgctggagca cttattagcc acgtatctga gagatgaaat
    17041 caaaggaatt attgatatct ctcctatggg atgcagaacg gggttctact tgattttatg
    17101 gaatgaacat gagcctgagg aaattgcact tgctttggaa aaaaccttga aaagaattct
    17161 ggaaacgaca gaggttccgg ctgttactgc tttggaatgc gggaactaca aggaccactc
    17221 tcttttttcc gcgcaggaat atgtgaagat tgtattggaa gctggtatta gccgcgatcc
    17281 tttcgaaaga gtactttaaa atctatgatt tcgattgacc tatctcatca gacagcggta
    17341 gtgacaggcg gcaagtcagg cataggcaag ggaattgtag agcttttcat tcaaagcgga
    17401 gctaaagtta tttctgctga tatctcttat gaagagccgt atagagtggt caatccacag
    17461 ttggttgaaa ctcaattgga catatccaaa ccggatgata tcgaaagatg gtgcgatcta
    17521 ctaatcagcg aggcgggagt tcctgatata ttggtgaact gcgcgggtac ttctacgatg
    17581 gattatgtca ttgatagtga gttagctgat tgggagaaag tattttcgat caattcaacc
    17641 ggattatatg taacgtccaa acgttttgcc aaagaaatgg tggcagctcg taaatcagga
    17701 cgaattattc aaatggcttc gcaggctgga aaaaatggat atcgggccat gggcggatat
    17761 tgtgcttcca aacatgcggt tcttggcttg accaaggtga tggctattga gcttgcccgg
    17821 caaaatattt tggtaaatgc ggtctgcccc ggcattgtag aaaccccgat gaagcatcgc
    17881 gaacggattg aagggggcgt cattcgcgga atgaccgctc aagaaatata cgaagaagat
    17941 tgttcacagg tacctttggg gagaacggcc gaggtggagg atgtcgccaa tgtggtgctg
    18001 tttctggcca gtccgctctc agcatatatg acaggacaag cgattaatgt tacaggtgga
    18061 atgacgatgc actaacatac tagcatgatc tgggggaaaa caacatgaga aaatcgttcg
    18121 ttttactatt agggattagt ttattattgg ttgccgcagg atgcggtaat aaaagttcag
    18181 acagcaatgg ctccagcgcc gcttccggtt cggaaacgca aaaagtagtc attggctcca
    18241 tgggctctga cgcccagatc tggaagcata ttgcccagtc ccaggccgca aaggatgcca
    18301 agctggacat tgaagtgaaa gaaattaacg gcggaatcga aacgaacaat gcgaccaaag
    18361 aaggcgaagt agacgtgaat gcattccaat cgtgggcgta cctggttagc tataacaaag
    18421 agagcaaagc tgatttgaag gcgatagcca caacctatct ggagcctatg gggatttatt
    18481 cgcaaaaatt caaaagcatt aatgaagtga ccgacggggc tctggtagct ttggcagata
    18541 acccggccaa cacggcaaga ggtttaaagt tattggaagc ctccggtttg attaagctta
    18601 aggctgactt taatgatgcc ttgggtacag tcaatgatat taccagcaat cctaaaaacc
    18661 tgaaatttga actcattgat gataaaacag gaccacgagt gattcaagat gtaggtttgg
    18721 tgctgattgg gaatacgatt gctttagaag ggggcctgaa tgtactgaaa gattccttgt
    18781 tccatgagga aatcagtcag gcaaccaaaa ataatattaa cgtcctggtt acttcatctg
    18841 ataaggcgaa tgacaaaggg ctgcaaaagt tagcggatct ctatcataac gaggatactc
    18901 aaaaatacat taaagatgaa tttggtggca ccaaagtaga ggttaaagag ccggtttctt
    18961 atttggaaga acaaactaca aaataaataa aagaggtcag ccagttgttc tggttgacct
    19021 cttttgttag tagtcgactt gagtttgagt atgggtttcg attcgataat gtttggggga
    19081 gagtcccttt acctttttaa aaattttcga gaagagtaaa gggtcgttat agccgactga
    19141 acgggaaata tcaccgattg aaagttcagc gtttcccatc atttcacatg ctttgttgat
    19201 cctatagcga accaaataat cctgaatgct tgtgttcact tgttgtttga ataacgaaca
    19261 taaataactt cgattgagtc cgataaaatt tgcaatgtgc tcaatggtaa tcttctgagc
    19321 ataattcatt tcgataaaat ccttcacttt ttccacgtaa atttccgccc ggctttcctt
    19381 ttgttcggga ggtgttaccg gaccgaattc tataagctcc gataacatta aacaaagcag
    19441 accggtcagt ctggtttccc gagctttagg gcattcactt gattcgttca ttcgctgcaa
    19501 atactgatga atcaaatggt ctccttcaaa gttgaggatt ggacgcgtca tcgttagacc
    19561 tgcttgcttg aggagtgttt ctgccagtgc cccgtcaaat ccaaaccagc aataagacca
    19621 aggattcact acatcggctt gataataagt aatgacctga gggcagatta gaaaccactg
    19681 tcctttctgc aagcgataac tgaacccact gacctcgaag gtaccttctc cgtccaaaat
    19741 ataatggagc agatagtgat ctcttatcgc aggtccaaaa aagtgactcg gtatgcattc
    19801 ctctatgcca aactgagtta gatacaattc agtatgctgt ttactacgcg gcaaatattc
    19861 tatcatgcta aatctcctta tgtaaattat caagcattat aacataaata gtgagcacca
    19921 tgccatgtac ttcatatcta aaattaatat atgatttctg tagaacctat ttctatattg
    19981 ttgaatctta tcaagcttta caccatatga acatagttga tggctgttac aaaatgcttc
    20041 ttctgagtgt ctttttggtg tggaactccg atgattatta tctatgagag gggttatttt
    20101 cccaatgggt atcattgttc aagagcaaac agggctgttt catttgcagt cgtcgggcat
    20161 gagttatatt attcagattg tggatggatt tcctgtgcat gtatactggg gagacaggtt
    20221 gaagcaccgc gaacccatgg ctgacctatt gcttcacact cccgcgacgg ctggattgga
    20281 tcggctaccg caagaatatc cgcagtatgg tagcggggac ttccgtaacc cggcatatca
    20341 agtagagctt gaggatggaa ctcgtatcac ggagttaaag tatattggct accggatcac
    20401 taagggaaag ccatcattaa ccgggcttcc ggccgtatat accgaaaatg aagacgaagc
    20461 ggatacgctg gaactggagt tacaagatga tttttcaggc cttaaagttg ttcttcttta
    20521 taccgtcttc acggatcgga atgtaatcgc tcgctcggct cgtttgagta atgcgggagc
    20581 caagaacctt cggcttctcc gtgctctaag tgccagtgtc gatttttctg gtaaaagcga
    20641 tttagagttc atgtatcttt cgggagcatg ggctcgggag ggaaatatta cccgcaaatc
    20701 gattcttcaa ggtgaaaccc gaattgatag taaaaggggc atgagcagcc atcaactcaa
    20761 cccttttgct gcattggtca ctcggggaac aacggaaagc tatggtgagg tattcggctt
    20821 tagcctcgtc tacagtgggg gctttgaggc gggagcagaa atagattcat tcggctctac
    20881 acggtttagc atcggtgtga actcctttga tttttcgtgg ttactgagcc caggtgagag
    20941 cttccaaacg ccagaagccg ttatggttta ctctggtcaa gggctgggag aaatgtcgcg
    21001 tacatatcat cgcttgtatc ggactcgtct ttgccgaggg aaatatcggg atgaagaacg
    21061 ccctattctg gtcaataact gggaagctac ctattttgac ttcaatgcag ataagctggt
    21121 atcgatagcg aaggaggggg cagagctagg catcgaactt tttgtcttag atgacggttg
    21181 gttcggaaaa cgggattccg acaattcgtc tctcggcgat tggtacgagg atcgtcggaa
    21241 gctgccagac ggactcgcgg atgtcgcgaa ccgtatcaat cgactgggcc ttaagttcgg
    21301 gctctggttt gagccagaga tgatctctcc agacagcgag ttgtaccggg agcatccaga
    21361 ttggtgcctt cacgttccag gacggcgacg cagtgaagcc agatggcagt tggtgctgga
    21421 ctatactcgc aaggaagtac gcgattacat ctacgattcg ctggctgcca ttttctccag
    21481 cgccccagtt tcttacgtga aatgggatat gaatcgctgc ctgacagaaa tcggttccgc
    21541 agctctgccg ccggagcgcc aatctgagac ggcccatcgc tatgttcttg gattgtatga
    21601 gctgctggag cgcgtcacca ccgaatttcc gcatattctt ttcgagagct gttcaagtgg
    21661 cggaggacgt tttgacccag gcatgcttta ctacatgcct caagtctgga ctagtgataa
    21721 taccgatgcg gtggaacgcc tgaagattca atatggaact agccttgtct atcctgtaag
    21781 cgccaccgga gcgcatgtgt cagcagttcc gaaccatcaa gttggacgca taacacccct
    21841 tgattttcga ggtgatgtgg ccatgtccgg aaattttgga tatgagcttg atctcacgaa
    21901 attcaccgat gaggaaaaag agacggtcaa acgccaaatc gcagtatata agcagatacg
    21961 tggcttagta cagaaaggtg acttgtatcg cctaaagagc ccgtttgaag ataacgaatc
    22021 ggcttggatg tttgtttctg aagaccaaga ggatgccatc gtctactatt tccaagtgat
    22081 ggctgttccg aacgcgcctt ggcgagccct gcgccttgac ggactaaatc cagagctcga
    22141 atatgaagtt aagtcaggaa atagcgggca aaagtctatc catggggggg atcggcttat
    22201 gaagttgggc ctccctcttc tctacagaca gaaagactat gaaagtggat ggttcaggct
    22261 tcgggcatta aggtccaaca aggcttaagg cttaaaggat cagtacaaca gtacaattgg
    22321 caaaagataa aaaacaatcg attgagttat gcatgcccct ttttgtataa aaggggcatt
    22381 ttgcgcgcag cagccgtact gatcagggag gggcaagcca tgttttttat acgaatgatg
    22441 aatgacatga aactgagaaa gaagatgacg cttacattca tttcggtagc tgttcttccc
    22501 ttgctgttat gtggcctgtt tctgacgggg aagcttcgag aggccgttat taaagacgcc
    22561 tttatgcaag tgtccaacaa tgtcgagcgg gtccgaaatc gtacagaaga attgattaaa
    22621 gtgccgctgg acatctcgta tcggctaacc aatgacaatc ggatgaaaat ggtagccagc
    22681 caaaagtatg acagctacat cgaagtcatt cacgcttacc gggagtatac aggtattcgt
    22741 gactacctcc aattgtacaa agagatatcc ggcatccgtg tctatgtccc taatcctgga
    22801 gcacttaata attgggagtt tatccagccg gacaaaagaa ccacaaccgc aggttggtac
    22861 aaggaggcca tcgcgcagaa aggattggct ggctggaatt taatcaagga tgagaggaac
    22921 gatgccgatt atctcagcct gattcgatca ttctcagtga attcaccagg aagaaaaggg
    22981 gttctagtca taaatgtgaa ccagcgccaa ttaaattcaa tcctaaatca ggaatcgttc
    23041 cctaccttga tcgtggatag ccggaatcag attgtcgcgt ccaatgaagc agagttgttt
    23101 gggaagaatc tttctgaaat tcatgccgac gaaaatatac tttt
//
