LOCUS       NZ_CP117876            20243 bp    DNA     circular CON 26-MAR-2024
DEFINITION  Paenibacillus sp. KACC 21273 chromosome, complete genome.
ACCESSION   NZ_CP117876
VERSION     NZ_CP117876.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus sp. KACC 21273
  ORGANISM  Paenibacillus sp. KACC 21273
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5354372)
  AUTHORS   Kim,S., Heo,J. and Kwon,S.-W.
  TITLE     Genome sequence of Paenibacillus sp. KACC 21273
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5354372)
  AUTHORS   Kim,S., Heo,J. and Kwon,S.-W.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2023) Agricultural Microbiology Division, National
            Institute of Agricultural Sciences, Rural Development
            Administration, 166, Nongsaengmyeong-ro, Iseo-myeon, Wanju-gun,
            Jeollabuk-do 55365, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HiFiasm v. 0.16.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 186.1x
            Sequencing Technology             :: PacBio Sequel; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028736095.1-RS_2024_03_26
            Annotation Date                   :: 03/26/2024 01:21:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,697
            CDSs (total)                      :: 4,591
            Genes (coding)                    :: 4,576
            CDSs (with protein)               :: 4,576
            Genes (RNA)                       :: 106
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 15
            CDSs (without protein)            :: 15
            Pseudo Genes (ambiguous residues) :: 0 of 15
            Pseudo Genes (frameshifted)       :: 3 of 15
            Pseudo Genes (incomplete)         :: 11 of 15
            Pseudo Genes (internal stop)      :: 1 of 15
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:56:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4287255
            Orig. end                         :: 4307498
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP117876.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Korean Agricultural Culture
            Collection (KACC).
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20243
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="proteusin"
                     /region_number="8"
                     /rules="(PoyD or TIGR03793)"
                     /tool="antismash"
     cand_cluster    1..20243
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PoyD or TIGR03793)"
                     /kind="single"
                     /product="proteusin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20243
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10243](+)"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10243
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
     gene            302..1504
                     /locus_tag="PQ460_RS18840"
                     /old_locus_tag="PQ460_18840"
     CDS             302..1504
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018976178.1"
                     /locus_tag="PQ460_RS18840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQ460_18840"
                     /product="acyltransferase"
                     /protein_id="WP_274170750.1"
                     /transl_table=11
                     /translation="MSRERINEWALLRGFAFLAVVMQHSIGEYIYRSGSIQADSIMLGM
                     LYHFTRFGTLTFVFLAGAILFYQYGDGRKYRSVIFRRIGDIYIPFVVWTIIYWIVMQWI
                     FNAPLLRADSLQDIVQQLFAPTNGYHLWFVIMIFQFYLLFPLFRWLGKQFQTRLLENRS
                     PHEQKRHIVIMLIVIGIIYGWLMWLCYYAMPTWNVQGIWKIILDHRTSEFIFYFFYFVL
                     GGICGSAIQRWRAMIIKILPWTAVSFLIMYIWLGYDLLRFDPVAINLNVSTYLKPTTFL
                     AVVSHMLLMYGLALYLVERKSVMVRFLQWCGRYSFGGYLSHALILMGVSYFTRQITAPG
                     LNLVLTILTFMIVAPTAIALTSGLSRLPGGQWLTGSAGKKGNHSIRTHASRPQSTLPQD
                     S"
     gene            complement(1652..3388)
                     /locus_tag="PQ460_RS18845"
                     /old_locus_tag="PQ460_18845"
     CDS             complement(1652..3388)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF025854.4"
                     /locus_tag="PQ460_RS18845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQ460_18845"
                     /product="ATP-binding protein"
                     /protein_id="WP_273615148.1"
                     /transl_table=11
                     /translation="MKQRKSLVPKPFPVTVYILAVMTVVLIIVNTTYYVTTRKALISVQ
                     EQNMRAITDQIRSSIKLSQSGEAFVEDLIGENLRMAAQAAQSKIGSDMNEVTNQQLAEV
                     SKEVGVDRITLLAPSGNNIVPIRSSDPNELSVKEEWRADWLKAVQELLARKTPTVDIGQ
                     KLPDYWGAPMISKVDNANSAGEKWGYYYDGKTNYVINVYTNDKSVREFQEKTGVEAIIR
                     EILNGERSRQTLGIAIFNPPIFLDQANQFNSHGVIWYSDNETLYNDYSYKSATDKTNIK
                     QVNKSGNTISITDEFDNVPVLKTFIPVELTYPAIITVVSDLTEVQQTLNEQLIRLTLTI
                     SACSIAIIALVLGLITILNRRTEAAAQSVQNVYLENIDALFNSIKEQRHDFNNHVNTIQ
                     LLVKMKKYDDLSTYTAELVGESIAMNQIININLPALSALIQAKTTQAYDRRIKFEYDIS
                     NLKSVQFGTVKSTELVKIVSNLIDNAFDAVSETDKPDKMVKVTGRVRGEQLTFTVGNNG
                     NPIPEKLKQQIFEAGFSTKPLNRKNSGLGLAIVQKILSKHRGIIRVESDEEWTEFSVRL
                     PL"
     gene            complement(3689..3991)
                     /locus_tag="PQ460_RS18850"
                     /old_locus_tag="PQ460_18850"
     CDS             complement(3689..3991)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811510.1"
                     /locus_tag="PQ460_RS18850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQ460_18850"
                     /product="hypothetical protein"
                     /protein_id="WP_274170751.1"
                     /transl_table=11
                     /translation="MKWYTFGQMIASIRVGQKASTMDGARIIMRTTKGIIWFNGREQGQ
                     YVQIKDYLFSDLWHMYEDEEGLISSSEREQYEQHEYEMIENQYVEWWTERKQSLK"
     gene            complement(4003..4461)
                     /locus_tag="PQ460_RS18855"
                     /old_locus_tag="PQ460_18855"
     CDS             complement(4003..4461)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811511.1"
                     /locus_tag="PQ460_RS18855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQ460_18855"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_274170752.1"
                     /transl_table=11
                     /translation="MGTKLPLSPLVKLLDMNEHREGGWYKEMWKASFEIPKDILPEQYS
                     GPRFSATSIYFILHGDEISDWHVVHSDELWLIHSGSPLELTLGGKGDQPIEGKKMILGM
                     DIEAGQTPQVLIPAGEWQMARPLGNDPVFVSCVVAPGFHYDDFKLIER"
     gene            complement(4502..4945)
                     /locus_tag="PQ460_RS18860"
                     /old_locus_tag="PQ460_18860"
     CDS             complement(4502..4945)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811512.1"
                     /locus_tag="PQ460_RS18860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQ460_18860"
                     /product="OsmC family protein"
                     /protein_id="WP_273615146.1"
                     /transl_table=11
                     /translation="MKHQFVLDANWQGGRNSEGTIESGNLKTAISIPQPMGGPGIGTNP
                     DEMLLGAAATCYIITLAAMLERSNITVARLTMKSEGIVDVTNNIFTYEQLIHRPEIVLS
                     AESADQVEKATVLAHKAEQSCMISRAIAGNVTITTQPLISIAD"
     gene            complement(5103..5972)
                     /locus_tag="PQ460_RS18865"
                     /old_locus_tag="PQ460_18865"
     CDS             complement(5103..5972)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811513.1"
                     /locus_tag="PQ460_RS18865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQ460_18865"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_274170753.1"
                     /transl_table=11
                     /translation="MTTVIGMTWKELMRKKVVLMTLIMTVLFIIVFSFIARILGKTSGI
                     EPSQQLVAQFMTGASILTLGFFFGSFILAFLIIFSSFSSISGEAEVSMMQSMLTRPIQR
                     WKWYLGRWLGYTLFGIAYALVLYIAIVVIANIYATVPQSLVVHIQSFLLFALTVPLLVT
                     VTLLGATFFSALGNGVFMTMLYGAGWLGGMVEKLSSSAELKPEMARSLYNITGMISLVM
                     PADAIQRKMLAVILNVDQLAGMFNIDEQMRAGMGVGQVPSATFIFYAGIYTVIFFFWGM
                     RRFYKKDF"
     gene            complement(5972..6943)
                     /locus_tag="PQ460_RS18870"
                     /old_locus_tag="PQ460_18870"
     CDS             complement(5972..6943)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019911207.1"
                     /locus_tag="PQ460_RS18870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQ460_18870"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_337993941.1"
                     /transl_table=11
                     /translation="MAIDIQQLTKEYDNGRGCRNVTISVGEGEAFGFLGPNGAGKSTLV
                     KMLVGLTAPTSGSATLFGDPIGSLEAKRHIGYLPELYRYQEWLTGEEVVRLHSRLCGMD
                     QSTIKPRIKQLLDQVGIGKRGTDRVKHYSKGMQQRLGMACALVNDPPILFLDEPSSALD
                     PIGRLEVRELLKNLKNEGKTIFLNSHLLEEVESLCERIALLNNGQILRHGQVSQVLYTQ
                     TKWRFKVGGFTPEILPWLSETSGISIERYATPTILSATATLPVGQETVWLEATIDNEEQ
                     IGWLNTLIVNQGMTLYNVEPVKEKLEEWFMDAVSGLSHRGEQ"
     gene            complement(6949..8097)
                     /locus_tag="PQ460_RS18875"
                     /old_locus_tag="PQ460_18875"
     CDS             complement(6949..8097)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PQ460_RS18875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PQ460_18875"
                     /product="hypothetical protein"
                     /protein_id="WP_274170755.1"
                     /transl_table=11
                     /translation="MSKFPQDPNNIQPTEPVDSSNATDEAWAKLKSQLVNETPHSNWEK
                     WANEPHLFQIDDPSSQPQQSQRSVITMKKSNEEQSYTSSTETEPTVKRRRKMSFTRKRW
                     TTGIAACVVAGAVIATPFGNNAMAALLDQFRVQTLTAVDSQQLSDMFDQYRGDAEFDEQ
                     ENRFGIFSSTYGNIEGDFSPSKAAELLNYTLVKEAAQDNKETVNVQSSRTRTLIMNIDE
                     VNKAIQSLGGKELLPQSLNNTPISIHFPESIYYTMFKGENVASLTQTKVPTVQFDASVS
                     TDEVFKAIADLPFLPQSLKDELQSDKVINGSLPLPVESGGKTERLTIAGEPVLISFYKV
                     NDDGITYSATWLHNGELFTFDGGSAYTTYESFTKEIEKLIQS"
     gene            complement(8123..8629)
                     /locus_tag="PQ460_RS18880"
                     /old_locus_tag="PQ460_18880"
     CDS             complement(8123..8629)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811516.1"
                     /locus_tag="PQ460_RS18880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQ460_18880"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_273615142.1"
                     /transl_table=11
                     /translation="MDIPEPEQFQQIFYEHYPIVKRKLHALLRDEAIADDLAQEVFLRL
                     YRNPPDDPQAIGAWLHRVLTRIAYDYMDKKARERRLQNKQEQYYDLQHSPPSGEDIVIQ
                     QMEQEEVQEWLEQLPQRDRQALLMKYSGYSYAEIAEELQLKQPIVGTLLHRATNKLRKK
                     MLRST"
     misc_feature    8813..8829
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 24.79"
                     /tool="antismash"
     gene            8913..9935
                     /locus_tag="PQ460_RS18885"
                     /old_locus_tag="PQ460_18885"
     CDS             8913..9935
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PQ460_RS18885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PQ460_18885"
                     /product="hypothetical protein"
                     /protein_id="WP_274170756.1"
                     /transl_table=11
                     /translation="MLWLKPFELQLDAVFEEAKQKVAHFPKPLHELGLAYLAKFDIRQK
                     HSTKNYVCYLLPFWIAETIQAHTAKAVSHPSSATVSSLHLQSLPELSHRMGVANIFCML
                     HFFIQDDLMDTPNLSTDQLHDLIPLSQLFWNEFVSICGENLGNDSSFWQYYKQFLAEWA
                     SAVYNEADADYLFEQPQQIASKVSPLKISLIAMLLQLDCMYMLPDLLQQLDQALIVLQM
                     NDDLSDWQEDMIERNYNCLLAFIRYEAVEHHQALFSDKVTAVQVQQAIYDQEVIRRYAQ
                     YAQSSFTSDPSLFVSDSLIAFRNYLIEQLHEAATSIHEARNTLLQGSLLYFIQKDLTSS
                     "
     gene            10001..10243
                     /locus_tag="PQ460_RS18890"
                     /old_locus_tag="PQ460_18890"
     CDS             10001..10243
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proteusin: TIGR03793"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811518.1"
                     /locus_tag="PQ460_RS18890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQ460_18890"
                     /product="NHLP leader peptide family RiPP precursor"
                     /protein_id="WP_204825378.1"
                     /sec_met_domain="TIGR03793 (E-value: 9.4e-17, bitscore:
                     58.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSQAIFQAQVIQKAWEDPSFMEMLKTDPKSALKDVLGISFPEHV
                     QLKTVEEKSDEFYLVIPPKPSSMMADAKVKVDAGW"
     gene            complement(10339..12234)
                     /locus_tag="PQ460_RS18895"
                     /old_locus_tag="PQ460_18895"
     CDS             complement(10339..12234)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019635990.1"
                     /locus_tag="PQ460_RS18895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQ460_18895"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_274170757.1"
                     /transl_table=11
                     /translation="MKILSKALIGVLIAVIVVVLALSLFSTQSEKRTGHSINYWQIKWQ
                     SQNTLTSKPWDSDQDSPWISSEIMKDGKPVNSSSAWIRIPLPELSWNTAGVLIPELNGK
                     HIIVYLDQDKIFESKRSYAYEQNQLLLPLTKQDSYKLLYIWVESAREQISLKQGIMVGD
                     YQDMLISYVSSDLIDVVLGSACIFISLVMVICSVFLRRDQLRMWLSLAAIILSLGILVV
                     TYSPFLFTFYPTYYKLYSVLLDLSLFILLPALLYFFECVFGSGYKGIITKMKKIQYAYS
                     FICVMAMIFNILTNERYFAVYYFISVKTLGILLILQLLILMVVAVTYAFRKNKDAILFA
                     SGFSIFALISGGELTWFYIQAGSYSVTLWKWGVMIFVISLISVMARRFAQNHQQMVLYS
                     SRLELFNNELQRSEKMDIISELAASVAHEVRNPLQVTRGFLQLLQMNTDDKGREHLKIA
                     LEELDRASAIITDFLTFAKPEFDKVNTLNLAQEFQHIEGIMRPLATLAGGTITMNIPEN
                     IDIRGNSSKFKQALINIVKNSIEALPEEGKIHIWAEQNDKEIEIHIQDNGSGMTEEELK
                     RLGEPYFSNKTKGTGPGLMVTFRIIEALGGVLEFKSKKNVGTEAVIHLPAADPQV"
     misc_feature    complement(12484..12497)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.64"
                     /tool="antismash"
     gene            12574..12831
                     /locus_tag="PQ460_RS18900"
                     /old_locus_tag="PQ460_18900"
     CDS             12574..12831
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PQ460_RS18900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PQ460_18900"
                     /product="hypothetical protein"
                     /protein_id="WP_273615139.1"
                     /transl_table=11
                     /translation="MTDDKHYDDVFWKTRNTILNDEDSQTNTEEELPEDAKKAVILPEK
                     MDNPLFGQLADEEDAGPHPSADPEDPESDAAHISNDKQEE"
     gene            complement(12927..13595)
                     /locus_tag="PQ460_RS18905"
                     /old_locus_tag="PQ460_18905"
     CDS             complement(12927..13595)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009589560.1"
                     /locus_tag="PQ460_RS18905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQ460_18905"
                     /product="ribonuclease H family protein"
                     /protein_id="WP_274170758.1"
                     /transl_table=11
                     /translation="MAKSKYYVVWEGHHPGIYTSWADCQQHTNGYKDAKYKSYETLAEA
                     EKVYAEGWKKHWGQGKSNSSSNSTSGNSYSKRTSSSATISKDLIDYDSISVDVGTRGNP
                     GPVEYQGVDTQTGKVIFTCGPIAKGTNNLGEFLAIVHALAYLHRQGSSKTIYSDSANAL
                     KWVKQKKAVSTLVRDESTAEIWNLVDRAEQWLRTHKYDNKILKWETKSWGEIKADYGRK
                     "
     gene            complement(13676..14905)
                     /locus_tag="PQ460_RS18910"
                     /old_locus_tag="PQ460_18910"
     CDS             complement(13676..14905)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015890927.1"
                     /locus_tag="PQ460_RS18910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQ460_18910"
                     /product="MFS transporter"
                     /protein_id="WP_274172970.1"
                     /transl_table=11
                     /translation="MENFSWKRNLVVLWLGVFFCSTAYSISIPFLPIFLKADLGVTSNL
                     EIWSGIAFGITFLASALISPFWGSLSDKYGRKPMLIRSGFSLAALYLINYFVTDPYLFL
                     VVRIFQGLLAGFVPASIALVGTNTPENKTGYALGVMATSGATGTIIGPLIGGVVSYYFG
                     NRNTFLFSAAIVLIAALIATFWAKEHNFNRSAKRSHVRDDLKQAAGNPIFVALLILAGI
                     STFSIMILEPLITIYVQSLGVSNNNASLSSGIVFSAVGVATLIMAPRWGKVGGKIGYGK
                     ILFIGLLGSGIGNLLQFFFTNIWGFGILRFAYGLFYAAVLPSINALIVKVTPSDFRGRA
                     FGLNQSASQIATMAGPIIGGLLGHWIDIRWVFVINGVMLLICALFVKRRSWEIPVLENS
                     SESIGKVPHS"
     gene            15131..15616
                     /locus_tag="PQ460_RS18915"
                     /old_locus_tag="PQ460_18915"
     CDS             15131..15616
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PQ460_RS18915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PQ460_18915"
                     /product="hypothetical protein"
                     /protein_id="WP_273615137.1"
                     /transl_table=11
                     /translation="MNKPFDDNRDAAAQEYNRYRTTEPVTSDVEDELRTIPENDLDIIN
                     PTMRDEEGIQPITSEDVAVREANAELEDEHDVSPYSIDLDVAETPIDTGNDLNSDPLTD
                     LEDVTMDDEFPDIPDADLLDGETPVDPAAVPLEDQDAHGTDILNGSTGEDEPDRYGR"
     gene            15641..15850
                     /locus_tag="PQ460_RS18920"
                     /old_locus_tag="PQ460_18920"
     CDS             15641..15850
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006208682.1"
                     /locus_tag="PQ460_RS18920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQ460_18920"
                     /product="hypothetical protein"
                     /protein_id="WP_273615136.1"
                     /transl_table=11
                     /translation="MSTHDKDQDKEKKNLVTERDNDDEFGLFKEDSFPDSAPDEIQKRV
                     IDNELPHDNELPRHEEDKDKPEIE"
     gene            complement(15915..17987)
                     /locus_tag="PQ460_RS18925"
                     /old_locus_tag="PQ460_18925"
     CDS             complement(15915..17987)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006208679.1"
                     /locus_tag="PQ460_RS18925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQ460_18925"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_274170759.1"
                     /transl_table=11
                     /translation="MLHSLTAIDNYRNLGYLSADNPYLWLHYLVSAEERIVNLERVTTL
                     QELSNANPVLDYVERTLRILDQLRVSYWQKEMIEEVLIWSETAKGGTMRERIRWQEQGI
                     NLFVHNEGSAELYMHASADPQQERTQLVTTLIRTHGLIGQCLRGEVPFAENFPLTDQVS
                     HGILSPEEMKTTLLILNRCIIEAVSSELWQQVQDDVLALIQPIVYQEHPVGWTTEDRIL
                     RLRAASIHKGENTVESLHQLNAQINVEQSFALLDHQTFWYVEAALQDFSFEEFAKIFTL
                     ISHIVPKDVRHISFERLMNTMYYDYKGIKKVNVYKKRMIEKVLAECSWDQLSTGTWGQD
                     SPHLSYECVQEPHIADTVFFNFVFSPAAEKLIEFCIEAEKSPLYEKAVLLLFDLFGLRR
                     DAYDRFHNEESYLEMMNQTVDYKRILLRYIVGETIIDIGPGGGVMLDLIEEEWSSDKRA
                     IGIDISENVIEALQRKKQLEGRSWEVMKGDALALREIVEPGSVDSVLFSSILHELYSYV
                     PFNGHKFNLETVAAALSSAYDVLSKGGRIIIRDGIMTEPTGQKRRIQFLQDDGLSALER
                     YAQDFVGRSIDYEVTGEQEVIMPVNDAMEFLYTYTWGEEAYVHEVQEQFGYMTPSQYRT
                     FIEQTLGAQAHIVHLESFLQAGYTEALQPKVNITDEWGESVPLPDSTCIIVIEKT"
     gene            complement(18097..19356)
                     /locus_tag="PQ460_RS18930"
                     /old_locus_tag="PQ460_18930"
     CDS             complement(18097..19356)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015254.4"
                     /locus_tag="PQ460_RS18930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQ460_18930"
                     /product="pectin acetylesterase-family hydrolase"
                     /protein_id="WP_274170760.1"
                     /transl_table=11
                     /translation="MVTERQKGESYTAQNKSIHRTGRVSGKRGIEMVLTTIEWLIIVAV
                     VVVVILFVIKRPTRVVSFAESPLYKWNRVDLSGIVVAGDGSPYYLLTKRGKSKNVVVYF
                     SGGGISWDRNTASKPFGLRTLLHNRELGYYFANIPFYKTDLLGGMLDNHREDNPFYDWT
                     IVYIPYATGDFHIGNNKVKYKGKGKIHFTAHYSGRPNTLKGLDWLFDHITEPDKLFIAG
                     ASAGGFGSAFWAPHIAEHYPNAQIYHYADGSYLSSHQWHHIIDEVWQSKFEQHFGYPIE
                     EDIIAAAFRYNAQKLPANTILLQSNTLYDKVLPSYEAVLNQQTIGLVSGDDVMTQSWSQ
                     GMLDSAGQLDQELDNYYYFVTDYGVGTKKRSTPHTLSPSRVFYTAEESGVKLSRWLGDI
                     INKDKLYSVGKEFVESPMGK"
     misc_feature    complement(20192..20201)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 16.6"
                     /tool="antismash"
ORIGIN
        1 taccgattat ctggtgaaca gcaaaaaatg gatggcaaat acgaaatatg taagtagtgt
       61 ggaatttggt acagaaatat ttggtggtga tggtcaaatt aatttttcga aatggaatgt
      121 agcggtacaa taacattcga ttaccatata cttcaaagac cttccttttc tttcaaggaa
      181 gttctttttt tagtcgacat ctgttgataa taaaacaaat ataattcatc ttctattaac
      241 aattgtctga tatactgctt tactagtgta aagaatggtt atggatgatt gaggtgaata
      301 tatgtctaga gaacggatca atgaatgggc attgctacgt gggtttgcct ttttggcggt
      361 cgtgatgcaa cattcgattg gtgaatatat ttatcgaagt ggcagtatac aagctgattc
      421 gataatgtta ggtatgcttt atcattttac acgatttggt acgttaacgt ttgtcttttt
      481 agccggagct attttatttt atcaatatgg agatggacgc aaataccgtt cggttatctt
      541 tagacggatt ggcgatatct atattccttt tgttgtatgg acaatcattt attggatcgt
      601 catgcagtgg atatttaacg cgccattgct tcgagcagat agtttgcaag atattgtaca
      661 gcaattattc gcacctacca atggatatca tctctggttt gtaattatga tttttcaatt
      721 ttatctgtta ttcccgcttt tccgctggct cggtaagcaa tttcaaacac gattattgga
      781 aaatcgctca ccacacgagc aaaagcgaca tatcgttatt atgttaatcg tcatcggaat
      841 catctatggc tggttaatgt ggttatgcta ttatgctatg cctacgtgga atgtacaggg
      901 gatctggaaa attattttag atcatcgtac tagcgaattt atcttttact ttttttattt
      961 tgtactgggt ggaatctgtg gttctgcaat tcaacgttgg agagcgatga tcatcaaaat
     1021 actgccctgg acggctgtat cgtttttgat tatgtatatc tggttaggtt atgatctgtt
     1081 acgctttgat cctgtagcta ttaatctaaa tgtatcgaca tatctcaagc cgactacctt
     1141 tttggcggtc gtgagtcata tgttgttgat gtacggatta gctttatacc ttgtagaacg
     1201 aaaaagtgta atggttcgct ttcttcagtg gtgtggacgc tactcctttg gtggttatct
     1261 atctcatgcc ctaatattga tgggcgtgtc ttactttacc cgccagatca cagctcctgg
     1321 actgaatctt gtgctcacaa tccttacctt tatgattgta gctcctacag ctatcgcact
     1381 aacgagcgga ctctctcgct taccgggagg acaatggtta accggatcag caggcaaaaa
     1441 agggaatcat tcgatacgga ctcatgcttc cagaccacaa tccacattgc ctcaagattc
     1501 ttaaaataaa taaaaccgct atgttctctt gtgacagaga atgtagcggt tttatttgtg
     1561 ctgttatcag cttatctcca tatgttacga acatatagag tatgattata aagattcact
     1621 tgatccatgt cttgcatggc atactttaga attaaagtgg taaacgaaca gagaactctg
     1681 tccattcttc atcactttca acccgaatga taccccgatg tttggacaaa attttctgta
     1741 ctattgccag acctaatcct gaatttttgc ggttaagcgg cttggtactg aatcctgctt
     1801 cgaaaatttg ttgttttaat ttttcgggaa tcggattgcc attatttcca actgtgaagg
     1861 ttaactgttc tccgcgaaca cgtccggtca ctttgaccat tttatccggt ttgtcggttt
     1921 cgctcacagc atcaaaagcg ttatcaatta gattactaac aatcttaacc agttctgtcg
     1981 atttcactgt cccaaattga accgatttga gattactgat atcatattcg aacttgattc
     2041 gacggtcata cgcttgtgtg gttttggctt gaatcaatgc agacaatgca ggcagattga
     2101 tattgataat ctgattcatc gcaatcgatt cccctaccag ctcagcggta tacgtcgata
     2161 agtcgtcata ttttttcatt ttgaccaata attgaatcgt attcacatga ttgttgaaat
     2221 catgacgttg ttctttgatc gagttaaaga gtgcgtctat attttccaaa tagacatttt
     2281 gcacactttg cgctgctgct tcggtgcgac gattcagaat agtgatcaat cccaatacca
     2341 acgcaataat agcgattgaa caagcagaaa tcgtcagtgt taatcggatc agttgttcat
     2401 tgagtgtctg ctgaacttct gtcaaatccg atacgaccgt tataatagca ggatacgtta
     2461 actctaccgg tataaatgtt ttgagcacag ggacattatc aaattcatct gtaatagata
     2521 tggtattccc tgatttatta acttgcttaa tatttgtttt gtcggtagca ctcttataag
     2581 agtaatcgtt atataatgtc tcattatcag agtaccagat cacaccatgc gaattgaatt
     2641 gattcgcttg atcgagaaag ataggcggat taaaaatagc aattcctaat gtctgacgac
     2701 tacgctcacc attcaggatt tcacgaataa tcgcttctac gcctgttttt tcttgaaatt
     2761 ctcgtacaga cttatcattc gtatagacat ttatcacata attcgttttg ccatcgtagt
     2821 aataacccca cttttcacca gcagagttag cattatctac tttggagatc ataggcgctc
     2881 cccaataatc aggtagcttc tgtccaatat cgacagtagg cgttttgcga gcaagcaatt
     2941 cttgaaccgc tttgagccaa tctgctcgcc attcttcttt caccgataat tcattagggt
     3001 ctgaagaacg tataggaaca atattattac ctgaaggagc taacagtgta atccgatcta
     3061 cacctacttc tttgctcact tcagcaagtt gttgattggt aacttcattc atgtctgacc
     3121 caatcttaga ctgtgcagct tgagctgcca ttctcaggtt ctcgcctatc aagtcctcta
     3181 caaaagcttc tccactttga gataatttga tagatgatct aatctgatca gtgattgcac
     3241 gcatattttg ttcttggacc gaaatcaatg cttttcgtgt tgttacataa taggtagtat
     3301 tcacaataat caacacaact gtcataacag ccaaaatata tacagtcacc ggaaaaggtt
     3361 tgggtaccag gctcttacgt tgtttcattt taggaaatta acccccatct atatcagccg
     3421 cacttgctcc atgcctttta gccgtattaa aaatctaaat gcccgaatat cgacaaaatt
     3481 cgattctttt tttagtatca taccatgaac cgcataggac tacaccttat ttccataaaa
     3541 tcggactatt aatttatgga aaagatacct ttatttattg taacgtagcg gactgaataa
     3601 atctataaat aaaggtcctg tcagcactgt aaatgctatt caggaccttt ttttggataa
     3661 catagactat acaatttata gaaatagctt actttaagga ctgtttacgt tcagtccacc
     3721 attccacata ttgattttcg atcatttcgt attcatgctg ttcatactgc tcacgctcgg
     3781 aagaagagat caatccttct tcatcttcgt acatatgcca taagtctgaa aataaataat
     3841 ctttgatttg gacgtattgt ccttgctctc taccattgaa ccaaatgatg cctttggttg
     3901 tacgcatgat aatacgtgct ccatccatag tactggcttt ttgacccaca cgaatactag
     3961 cgatcatttg tccaaacgta taccatttca tctcatttgg tcctagcgtt caatcaattt
     4021 gaaatcatcg taatggaatc ccggcgccac cacacatgat acaaatacag gatcattccc
     4081 aagtggtcta gccatttgcc attctcctgc tggaatcaat acttgtggtg tctgtccagc
     4141 ttcgatatcc atacccaaaa tcattttttt gccttctatc ggttgatcgc ctttaccacc
     4201 tagcgttaat tctagcgggc taccggaatg aatcaaccac aattcatcag agtgaacaac
     4261 atgccaatct gagatttcat caccatgcag tataaaatag attgatgttg ctgaaaaacg
     4321 cggtcctgaa tattgttctg gtaaaatatc ttttggaatt tcaaaagaag ctttccacat
     4381 ttctttatac caaccgcctt cgcggtgttc attcatatct agcaatttaa ctaacggtga
     4441 taaaggtaat ttggttccca tgtatcatga ccttctttcc tcagagtttg gagtatttta
     4501 cttagtcagc aatactaatt aacggttggg tcgtgatcgt cacattacca gcaatcgcac
     4561 gtgagatcat acaagactgc tctgctttgt gtgcaagtac agttgctttt tcaacttgat
     4621 cggctgattc ggcacttaat acaatttcag gtcgatgaat caattgttcg tacgtaaaaa
     4681 tattattggt cacatctaca ataccttcag acttcattgt cagacgtgca acagtaatat
     4741 tggaacgttc aagcatcgct gcaagtgtaa taatataaca agttgcggct gcccctaaca
     4801 acatctcatc aggattagta cctatacctg gtccgcccat aggttgcgga atcgagatcg
     4861 ctgttttgag attgcctgat tcgatcgttc cttcgctatt acgtccaccc tgccaattag
     4921 catccaatac aaattggtgt ttcataatac attcatctcc ttgctctact tacacatttc
     4981 atcttgaaca ttttaccata ttctatggtt agtatcattt ccaaaataaa aacgttctta
     5041 ctaaacgcgt aattgcgtat agaagaacgc tctgtaagca atagaatctt ctgtcatatc
     5101 gtttaaaaat cttttttata aaagcgacgc attccccaga agaagaaaat aactgtataa
     5161 ataccagcat aaaaaataaa tgtagcagat ggtacttgac caactcccat accggcacgc
     5221 atttgctcat caatattaaa catccctgct aattgatcta catttagtat aaccgctaac
     5281 attttacgct ggattgcatc ggctggcatc actaatgaaa tcatgcctgt aatattatac
     5341 agagaacgag ccatttctgg cttcaattca gcactactgg ataatttctc taccatacca
     5401 cctaaccaac ctgctccata taacatggtc ataaatacac catttcccaa tgccgaaaaa
     5461 aaggtggctc ccagtaaagt cacagtaacc agtagaggta cggtaagtgc aaataataaa
     5521 aacgattgta tatgtacaac aagactttgc ggtacagtcg catagatgtt cgcaataaca
     5581 acaatcgcaa tatacaaaac taaagcataa gcgataccaa ataacgtata tcctagccaa
     5641 cgtcctagat accatttcca acgctgaatc ggacgggtta acatcgattg catcatactc
     5701 acttcagctt ctccagatat ggaagaaaac gagctgaaaa taattaaaaa agctaaaata
     5761 aaactgccaa aaaagaaacc taatgtcaaa atagaagctc ctgtcataaa ctgggctact
     5821 aactgctgac ttggttctat accagatgtt tttccaagaa ttcgagcaat aaatgaaaaa
     5881 acgataataa ataatacggt cataatcagt gtcattaaaa ccactttttt acgcattaat
     5941 tctttccagg tcatgccaat cactgttgtc attattgctc ccccctgtga cttagcccgg
     6001 atacggcatc cataaaccat tcttctaatt tttctttgac cggttctaca ttgtataagg
     6061 tcatcccttg attcacgatt aatgtgttca accaaccaat ctgctcttca ttatctatcg
     6121 ttgcttctaa ccagacagtc tcttgtccta caggcagtgt ggccgttgca gataatatcg
     6181 ttggtgtagc atatcgctct atcgaaatac cgctagtctc gcttaaccac ggtagaatct
     6241 caggtgtgaa tccacccact ttgaatctcc atttggtctg ggtgtataag acctgactga
     6301 cttgtccatg acgcaaaatc tgtccattat tcagtagcgc tatgcgttca catagacttt
     6361 ctacttcttc taacaaatga gaatttaaaa agatcgtttt accttcattt tttaaatttt
     6421 taagcagttc acgtacttct aagcgaccga ttggatctaa agctgaagaa ggttcatcga
     6481 gaaataaaat aggtggatca ttgactaatg cgcaagccat ccctagacgt tgttgcatcc
     6541 ctttagaata atgtttgact ctgtctgttc cacgcttacc gatacctact tgatctaaca
     6601 attgcttgat tcgcggctta attgtactct gatccattcc acacagacga ctatgcaacc
     6661 gaacgacttc ttcaccggtt aaccattctt ggtaacgata tagctcgggt aaataaccga
     6721 tatgtcgctt ggcttctaaa gaaccaatag gatcaccaaa taatgtagca cttcctgaag
     6781 tgggggctgt taatccaact aacattttga ctagtgtact tttccctgcg ccattgggac
     6841 cgaggaagcc aaaggcttcc ccttctccca cactaatcgt tacattgcga caaccacgac
     6901 cattatcata ttcttttgtt aactgctgaa tatcgatcgc cattgtactc atgattgaat
     6961 caacttctcg atttcttttg taaatgattc gtatgtggta taggcactcc caccatcaaa
     7021 tgtaaacaat tctccattgt gaagccatgt tgcactataa gttattccat catcattaac
     7081 tttatagaat gagatcaaaa caggttctcc tgcgatagtc agacgttccg ttttacctcc
     7141 tgattcaaca ggtaatggca gtgaaccgtt aataacttta tcactttgca attcgtcttt
     7201 aagcgattgt ggcaagaatg gcagatcagc aatcgcttta aatacttcat ctgtcgaaac
     7261 agaagcatca aattggactg ttggaacttt agtttgagtc aaagatgcta cattttcacc
     7321 tttaaacatc gtgtaataaa tgctttccgg gaaatgtata cttatcggag tattgttaag
     7381 ggattgaggt aacaattctt ttccgcctag actttggatc gctttgttaa cctcatctat
     7441 attcataatt aatgtccttg ttcttgaact ttgtacattt accgtttctt tattatcttg
     7501 ggcagcttct ttaactaatg tgtaatttaa taactctgct gctttggaag gactaaagtc
     7561 tccttctata ttgccatacg tcgaactaaa tattccaaat cgattttctt gttcatcaaa
     7621 ttcagcgtca cctctgtatt gatcgaacat gtcagacaat tgctgactat ctacagctgt
     7681 taatgtctgt acacgaaatt gatccaataa ggcagccatc gcattattgc caaatggagt
     7741 agcgattact gctccagcga ctacacacgc agcaatacct gttgtccatc ttttgcgagt
     7801 gaaactcatt ttacgacgac gcttaacggt tggttctgtt tctgttgatg aagtatatga
     7861 ttgttcttca ttagattttt tcatagtaat tacactcctt tgagattgtt gtggttgaga
     7921 tgatggatca tcgatttgaa ataaatgcgg ttcattagcc catttttccc agttagaatg
     7981 tggcgtttca ttaacaagct ggctttttaa ttttgcccat gcttcatctg tggcattgga
     8041 tgaatctact ggctctgtag gctggatgtt attagggtct tgtggaaact tgctcacgtc
     8101 tattcctcct tttgctcttt atttacgtag aacgtagcat ctttttacgt aatttattgg
     8161 ttgcccgatg tagtaatgta ccgacaatag gttgctttaa ttgaagttct tcagcgatct
     8221 ctgcgtaact gtaacccgag tatttcatga gtaaagcttg cctatcccgt tgaggtaatt
     8281 gttccagcca ttcttgtacc tcttcttgtt ccatttgctg tatcacgata tcctcacccg
     8341 aaggtggaga gtgttgaaga tcatagtatt gttcttgttt attttgcagt cggcgttctc
     8401 ttgccttttt atccatataa tcataagcaa tccgggtcag aactctgtgt agccaagccc
     8461 ctatcgcttg cggatcatcg ggtggattgc gatatagacg gagaaagact tcctgtgcca
     8521 gatcatcggc tatagcttcg tcacgtaaca atgcatgaag tttacgtttg acgattggat
     8581 aatgttcata aaatatctgt tgaaattgtt ccggttccgg aatgtccatg ttttcatgct
     8641 cctttccgct gcagctataa gaaagacgag cggtattcac tttttgtatc tattccctag
     8701 taatttattt tttatcttta tgaatatgtc tatctactca ggctatatgt atgattttcg
     8761 acaatatcat acatgtatta ttgataattt tgttagtcaa cgtgtataaa gttcgatata
     8821 atagcacatg aacatccaat atattcaaat gatgtcgtat actacctgta aaaagttctt
     8881 tgcttatata agaatttgag gagtggaagc taatgctttg gttaaaacca tttgaacttc
     8941 aattagatgc tgtctttgag gaagcgaagc aaaaagtagc ccattttcca aagccactac
     9001 atgaattagg attagcctat ctagccaaat ttgatatccg gcaaaaacat agcaccaaaa
     9061 attatgtctg ttatttgtta cctttctgga tagccgaaac gattcaagct catacggcta
     9121 aagcagtcag tcatccctct tcagctactg tttcttccct tcatctgcaa tcgttacctg
     9181 aattatcgca tcgtatgggt gttgctaata ttttttgtat gcttcatttt tttattcaag
     9241 atgatcttat ggatacacct aatttatcaa cagatcaatt acatgatctg atcccgctta
     9301 gtcagttgtt ctggaatgaa tttgtaagta tctgtggaga aaatctaggt aacgactctt
     9361 cgttctggca atactataag cagtttttag ccgagtgggc aagcgctgta tacaatgaag
     9421 ccgatgccga ttatttgttt gaacaaccac aacaaattgc aagtaaagtg agtccattga
     9481 agatttcttt aattgcgatg ttgcttcaat tggactgtat gtatatgtta cctgatctat
     9541 tacaacaatt ggatcaagct ttgattgtat tacaaatgaa tgatgatctt agcgattggc
     9601 aagaagatat gatcgaacgc aattacaatt gcttgctcgc ttttattcgc tatgaggcag
     9661 tcgagcatca tcaagcttta ttttcagata aagttactgc ggtacaagtg cagcaagcga
     9721 tctatgatca agaagttatt cgtcggtatg ctcagtatgc acaatcttct tttaccagtg
     9781 atccttcatt atttgtatcc gactctttaa ttgcatttcg gaattattta attgagcaat
     9841 tgcatgaagc agccacctct atccatgaag ctcgaaatac ccttttacag ggaagcttac
     9901 tatactttat tcaaaaagac cttacatctt catagatttt tagaattaga catgatacac
     9961 tgaataggta attataacca tttaagggag gaagattaat atgtccagcc aagctatttt
    10021 tcaagcacaa gttattcaaa aggcgtggga agaccctagt tttatggaga tgttaaaaac
    10081 cgatccaaaa tcagcattga aagatgtctt gggtatttct tttccagaac atgtgcagct
    10141 caaaacagtt gaagaaaaaa gcgatgagtt ctatctggta attcctccaa agccttcatc
    10201 tatgatggct gacgctaaag tgaaagttga cgctggttgg taatattccc cttgtattgt
    10261 taatatggtt ttctatactt atacatgtca tacaatcgta cacaaaaaaa ctgttacaac
    10321 cttctggcag cgaacccctt agacttgcgg gtccgctgct ggaagatgaa taacagcttc
    10381 tgtgcctaca ttctttttac ttttaaattc taatactccc ccgagtgctt ctataatgcg
    10441 aaaagtcacc atcagccccg ggcctgttcc tttggtttta ttcgaaaagt atggttctcc
    10501 taatcgtttt aactcttctt ctgtcatacc acttccgtta tcttgaatat gaatttcaat
    10561 ttctttgtca ttttgttctg cccagatatg aattttacct tcttcaggta aagcttctat
    10621 actattcttc acaatattaa tcaaagcttg cttgaacttg gaagaattgc cccggatatc
    10681 gatattttca gggatattca tagtgatcgt tcctcctgcc aatgtagcaa gtggtcgcat
    10741 aatcccttcg atatgttgga attcttgtgc taaattaagt gtattaactt tatcaaattc
    10801 aggcttggca aatgttaaaa agtctgtaat gatcgctgat gcgcggtcga gttcttctaa
    10861 ggcaatcttg agatgctctc gtcctttatc atctgtattc atttgtaaca attgcaaaaa
    10921 tccacgtgtc acttgtaacg gattgcgtac ttcatgagct acagaagcgg caagttcgct
    10981 gataatgtcc attttttctg agcgctgaag ttcattgtta aataattcta agcgactgga
    11041 gtagagcacc atctgttgat gattttgagc aaatcgtctt gccatcacag atattagtga
    11101 aatcacaaaa atcattacgc cccatttcca gagggttaca ctataacttc cagcttggat
    11161 ataaaaccat gttaattctc ccccgctgat caaagcgaaa atagaaaagc cggaagcgaa
    11221 taagattgca tctttgtttt tgcgaaaagc atacgttacc gctacgacca tcaaaatcaa
    11281 taattgaaga atcagcagaa tacctaatgt tttgacagaa ataaagtagt agactgcaaa
    11341 gtatcgttca tttgttaaaa tgttaaaaat cattgccatt acgcagataa acgaataggc
    11401 gtattggatt tttttcattt tagtaatgat gcctttgtaa ccactaccaa acacacattc
    11461 aaaaaagtaa agcaatgcag gcaataagat aaataagctt aaatcgagta aaactgaata
    11521 caatttgtaa taagtcggat aaaaagtaaa caaaaatggc gagtaagtta ccactaatat
    11581 gccaagagaa agaataatgg ctgctagact aagccacatt cttaattgat ctcgtcgtaa
    11641 aaatacagaa cagatcacca tgaccagaga gataaaaata caagcactac ccagtaccac
    11701 atcaatcaga tccgagctaa cataagaaat caacatatct tgataatcgc caaccataat
    11761 gccttgcttc agactaatct gttcgcgcgc cgattctacc cagatataca gcaacttgta
    11821 agaatcttgt ttggttagtg gtaataacaa ttgattttgt tcatatgcat aactacgttt
    11881 cgattcaaaa atcttatctt gatccaaata cacaataata tgcttaccat ttagttccgg
    11941 aatcagtaca ccggctgtat tccacgataa ttcaggcaaa gggatacgaa tccatgctga
    12001 tgaactattc accggtttgc catctttcat aatttcagat gaaatccagg ggctatcttg
    12061 atcactatcc catggtttgg atgttaacgt attttgcgat tgccatttaa tttgccagta
    12121 attaatagaa tgacctgttc gtttttcact ttgagttgaa aataaagata acgccaagac
    12181 gaccactata actgcgatta aaaccccgat taaggctttg gacagaatct tcatttcagc
    12241 acctcattat aaataaacta tgtaatacat attcgtttgg aaaatatacc cacctttatc
    12301 tattatactt gctctcttac ttcagagata ctattaattt tacaatgata caccatctac
    12361 aaaacatttc aaaatgcttg ctctatcgac tgattttgca tattattcta tattacttca
    12421 cgtctattta catcatgctt cagttgttga tataggatac aaatgacgaa taaataatga
    12481 acttttattt ataaaataat accgataccg tttggtcagc gacagactag ggtaagcact
    12541 attgatatac ggacgtattg gagggattta ctaatgacag acgacaaaca ttacgatgac
    12601 gtattttgga agacacgcaa cacgatttta aatgatgaag attcccaaac aaataccgaa
    12661 gaagaactgc ctgaagatgc taaaaaggct gtgattttac cggaaaagat ggataatcct
    12721 ttgtttggac agcttgctga tgaagaagat gcaggtccac atccaagtgc tgatccagaa
    12781 gatcctgaat cagatgcagc tcatatcagc aatgataagc aagaagaata atataggcta
    12841 acccctatca ttcatacaaa aagatacctg ttttcgcaca tattgtgaaa acaggtatct
    12901 ttttgatgtt ttttattatt ctaatcctat ttgcgtccat aatcggcttt gatctcaccc
    12961 cagctttttg tttcccattt caaaatctta ttatcatact tatgtgtacg tagccattgt
    13021 tctgcacgat ctaccaaatt ccaaatctcg gcggtagatt catcacgaac cagtgtagag
    13081 actgcctttt tttgttttac ccatttcagc gcattagcag aatcactata gattgttttg
    13141 ctactgcctt gacgatgcag ataagcaagc gcgtgaacaa tcgctagaaa ttcccctaga
    13201 ttatttgttc ctttggcaat cgggccacaa gtgaaaatga ctttacctgt ctgtgtatcc
    13261 actccctgat attctacagg ccccggatta ccgcgtgtgc ctacgtctac tgatatacta
    13321 tcgtagtcta ttagatcttt agaaatggtg gctgaagacg aagtacgctt actataacta
    13381 ttaccgctag ttgaattgct agaagaatta cttttgcctt gtccccagtg ctttttccag
    13441 ccttctgcat atactttttc agcttcagca agcgtttcat atgatttata tttagcatct
    13501 ttgtatccat tggtatgttg ctgacaatct gcccaagagg tatagattcc tggatgatgt
    13561 ccttcccata ctacataata ttttgacttt gccatacaga cctccatatt gtattccatc
    13621 attactattg gtttagattg tagtgttctt ttgctctgtg tgagcttaat tgtatttatg
    13681 aatgaggtac tttaccaatc gattcagagg aattctccag tacaggaatt tcccagctgc
    13741 gtcgcttcac aaaaagcgcg cagatcaata acataacccc attgatcaca aacacccagc
    13801 gaatatcaat ccagtgtccg agcagaccac cgataatcgg ccctgccatc gtagcgatct
    13861 gggaagccga ttgattcaat ccaaaagctc taccgcgaaa atcagacggt gtgactttga
    13921 caattaaagc attgatcgat ggtaatactg ccgcataaaa taatccatac gcaaatcgca
    13981 atataccaaa tccccagata ttcgtaaaga aaaattgtaa cagatttccg ataccgcttc
    14041 ctaataagcc gataaataag attttaccgt atcctatttt accacctact ttaccccagc
    14101 gtggagccat aattaaagta gctacaccga cagcggagaa cacaattcct gaacttaatg
    14161 aagcattatt gttcgatact cccaaacttt gtacatagat cgtaatcagc ggttccaaaa
    14221 tcataattga aaatgtactg atgcccgcca gtatcaatag cgctacaaat ataggattac
    14281 ctgcggcttg cttgagatca tcacgaacat gagaacgctt agctgaacga ttaaaattat
    14341 gttcttttgc ccagaaggta gcgataagag ctgcgatcaa tacaattgct gctgaaaata
    14401 aaaatgtatt gcgattacca aaataataac tcacaactcc gccaatcagc gggcctataa
    14461 tcgtacctgt tgcgcctgag gttgccatga ctcccagtgc ataaccagtt ttattttccg
    14521 gtgtgttggt gccgacaaga gcaatcgatg ctggtacaaa ccctgcaagc aatccttgaa
    14581 aaatacgcac caccaaaaat aaataaggat ctgtcacaaa ataattaatc aagtatagag
    14641 ccgctagact aaagcctgaa cgaatcagca tcggtttccg tccgtattta tccgataatg
    14701 atccccagaa tggtgaaatt aaagcactcg ccaaaaaagt aatcccaaac gcaatccctg
    14761 accatatctc taaattgctt gttacgccca gatcggcttt tagaaaaata ggtagaaatg
    14821 gaatagagat agagtacgct gtactacaaa aaaagactcc taaccacagt acaactaaat
    14881 tccgtttcca tgaaaagttc tcgatagcta ccacttatgc ctgcacgtcc tttccatcac
    14941 accacttaaa tatcttacat tctactcttg tttaacccat tctccaaatt cattatcttt
    15001 tataaggaat gaataacaat ttataagaga gcgattgcaa tattataaat tcgggtaaag
    15061 tacatgtaag ccaaatcaat acgtgaaatc aaaatagata tatttataac gttaagggag
    15121 atgaatgata atgaacaaac catttgatga taatagagat gctgcggcgc aggaatacaa
    15181 tagataccgg acgactgaac ctgtcacttc ggatgtagaa gatgaattgc gtacgattcc
    15241 tgaaaacgat ttagatatta ttaatcctac gatgcgtgat gaagaaggta ttcaaccgat
    15301 tacaagtgaa gatgtggctg tacgtgaagc taatgcagaa cttgaagatg agcatgacgt
    15361 gtctccatac agtattgatc tagatgtagc tgagacaccg attgatacag gaaacgactt
    15421 gaatagcgat ccacttacag atttggaaga tgttacgatg gatgatgagt tcccagacat
    15481 tccagatgct gatctgttag atggagagac tcctgtcgat ccagcggctg ttcctttaga
    15541 agatcaagat gcacatggaa cggatatctt aaacggatca acaggcgaag acgaaccaga
    15601 ccgttacgga cgttaagata gtaacaagga ggaatctacg atgagtactc atgataaaga
    15661 tcaggataaa gaaaagaaaa acttggtgac tgaacgcgat aatgatgatg aatttggatt
    15721 gttcaaagaa gattcttttc ccgattcagc accggatgaa attcaaaaaa gagtaatcga
    15781 taatgaactt ccgcatgata atgaattacc acgtcatgaa gaagacaaag ataaacctga
    15841 aatagaatag agtctataca ccaaaaagaa ccttttcctt attgattaca ggaaaggttc
    15901 tttttgattg tatattaggt cttttcaatc acaataatac aggtgctatc tggcaaagga
    15961 acagattcgc cccactcatc tgttatgttt acttttggtt gcaatgcttc ggtataaccg
    16021 gcttgtaaaa aagattctaa atgaacaata tgtgcttgtg ctcctaaagt ctgctcgata
    16081 aaagtacgat attgagaagg tgtcatatac ccgaactgct cctgcacttc atgcacataa
    16141 gcttcttctc cccatgtgta cgtatataga aattccatcg catcatttac aggcattatc
    16201 acttcttgct ctcctgtcac ttcataatca atcgaacgac cgacaaaatc ttgagcatat
    16261 cgttccaatg cggacagacc atcatcttgc aaaaactgaa tccggcgctt ctgccctgtc
    16321 ggttcagtca taatgccatc ccgaataata atgcgtccac ctttagaaag aacatcatac
    16381 gcactggata aagccgcagc gaccgtttcc agattgaact tatgcccgtt aaatggaaca
    16441 tatgaatata actcatgtaa aatcgacgaa aataatacac tatctacact gccaggttca
    16501 acaatttctc gtaatgctag cgcatcgcct ttcattactt cccatgagcg accttctaat
    16561 tgctttttac gttgcaaagc ttcgatcaca ttttccgaaa tgtcgatacc gatcgcacgt
    16621 ttatccgacg accattcttc ttcgatcaag tctagcatca ccccgccacc tggcccgata
    16681 tctataatcg tctcgccgac tatataacgg agcaatatac gcttataatc gaccgtctga
    16741 ttcatcattt caagataact ttcttcatta tgaaaacgat cataagcatc acgccgtaat
    16801 ccaaatagat cgaataataa caaaacagct ttctcatata gcggtgactt ttctgcttcg
    16861 atacagaatt caattaattt ctctgccgct ggtgaaaaaa caaagttaaa aaagactgta
    16921 tccgcaatat gaggctcttg cacacattca taactcaaat gcggactatc ttgtccccat
    16981 gtacctgtag acaattgatc ccaagagcac tctgccaaca ctttctcaat cattcttttt
    17041 ttgtagacat ttactttttt gatgcctttg taatcgtaat acatcgtatt cattaatcgt
    17101 tcaaagctga tatggcgtac atctttagga acgatatgac taatcaaagt gaatattttg
    17161 gcaaattctt caaatgagaa atcttgtaat gccgcttcta cataccagaa cgtctgatgg
    17221 tcaagcaatg caaaagattg ctctacatta atctgtgcat tcagttggtg tagactttca
    17281 actgtatttt ctcctttatg aatactggca gcccgtaagc gcagtatccg atcttcggtt
    17341 gtccaaccta caggatgctc ttgatagaca atcggttgga tcaacgcaag cacatcatct
    17401 tgtacttgtt gccataattc tgacgagacg gcttctataa tacagcggtt cagtatcagt
    17461 aaagtcgttt tcatttcttc tggtgataaa atgccatgac tgacttgatc agttaacggg
    17521 aaattttctg caaaaggtac ttctccacgc agacattgac cgattagtcc atgtgtccga
    17581 atcaacgtag tcactaattg agtacgttct tgctgtggat cagcagaagc atgcatatac
    17641 aattctgccg agccttcatt atgtacaaat aaattaatgc cttgttcttg ccagcgtatc
    17701 cgttcacgca tcgttccgcc tttggctgtt tcagaccata tcagcacttc ttcgatcatc
    17761 tctttttgcc agtacgatac tcgcaattga tctagaatgc gtaatgtacg ttctacataa
    17821 tccagtacag gattggcatt gcttaattct tgcaaagtcg ttacacgttc taaattgaca
    17881 attcgttctt cagcggatac caaataatgt aaccaaagat atggattatc ggcagataaa
    17941 taaccaagat tacgataatt gtctatagca gttaatgaat gtagcatacg gtcacatcct
    18001 tattttctcc agagtatagg gttattgtta gtttacccgt tttgatgtgg attgataata
    18061 aaaaagcgtt gaacctgatg ttcagcgctt ttgagtttat ttgcccatag gagactctac
    18121 aaattctttt cctacagaat acagtttatc tttgttaata atatctccca accaacgact
    18181 taatttcaca ccactttctt cagcagtgta aaaaacgcgt gatggtgata acgtatgcgg
    18241 tgtacttcgt ttcttcgtac cgacaccata atcggtcaca aagtaataat aattgtctaa
    18301 ctcttgatcc agttgtccgg cagaatcaag cataccttga gaccagctct gcgtcataac
    18361 atcgtctcca ctcaccaatc caatcgtctg ctgattcagt acagcttcat aggaaggtaa
    18421 gactttatca tataacgtat tggattgtag caaaatcgta ttcgctggaa gcttctgcgc
    18481 attgtaacga aatgccgccg caataatatc ttcttcgatc ggatagccga aatgctgctc
    18541 aaatttggat tgccacactt catcaataat atgatgccac tgatgagacg ataaataaga
    18601 accatctgca taatgataga tttgggcatt cggataatgt tctgcaatat gaggagccca
    18661 gaatgctgat ccaaatccgc ctgcactagc tcctgcgata aataatttat ccggttcagt
    18721 aatatgatcg aataaccaat ctaatccttt tagcgtattc ggtctaccac tataatgagc
    18781 tgtaaaatga attttgcctt ttcctttata ctttacttta ttgttgccaa tatggaagtc
    18841 tcctgtcgca taagggatat aaacaatcgt ccaatcgtaa aaaggattat cttcacgatg
    18901 attatccagc ataccgccta acagatcggt tttgtaaaaa ggaatattgg caaaataata
    18961 acctaactcc cgattatgca ataaggtacg caatccgaat ggcttggaag cggtattgcg
    19021 atcccagcta atccctccac cggaaaaata aacgactaca tttttacttt tgccacgctt
    19081 agttagcaag taataaggtg atccgtctcc cgctactaca ataccgctta gatctacccg
    19141 attccattta tacaatggcg attcagcaaa gctgactaca cgagtaggac gcttaataac
    19201 aaatagaata acaacgacaa caaccgctac aataatcaac cattcaatgg tagtcaacac
    19261 catttcgatt cctcttttcc cgcttactct tcctgtacga tgaatacttt tgttttgcgc
    19321 ggtgtacgat tcgccttttt gcctttcagt aaccatagat caggggtatc actcacatct
    19381 ttgatctcta attgaaaaga ggtattcggt aacgatctcg tgaatcgcaa aaataaccga
    19441 ttgccatcta cagccgattg actgactttc aactcatatg atttacccaa tccgatcgct
    19501 ggatataacg taaccgtacc aatagattgt ggatcaatac gcttattata aataatcatc
    19561 acttcatcag gtgctatacg aagacccgat gaaggtaaag gaggctctgc atacatatac
    19621 ccaccaatat ggtattcata agcggtccag ctctgatatc caagcgcata ggcatgatgt
    19681 tccagttcat ctatccaacg tcttcctttg atcatactgg atttggagcc gatatctgct
    19741 tgaataccaa gaggtaattt gggatgtaat gctcggatcg gtgcagctat actttcataa
    19801 tcgcgtatat agttagaggg tagaccacgc ttcatccaat ccggccaatg tgtctgcaaa
    19861 atatgcatat caggcttgac cagatcgatc atcgccagcg catccagccc ttgccattca
    19921 cgtagctttt gagtggcttc aggatcgcgt acagctaatg accatgtagc tactttaata
    19981 tccgggcgca catctctcgc tccatgctcg ccattaataa tttcatggat taatccattg
    20041 actgcttcta cacgcatatc aacccagcgc tcataaatat aaggaatttt tgtataataa
    20101 ttagctgcgg aagaacgggt aaaattgggc atatccattc catatttgtc gagaaaagct
    20161 tgctgtgcaa gcggtccgat atctccatat actccgcgtt cgattccgtt ccattctgga
    20221 aaataaggtt ctgcaatctc aat
//
