LOCUS       NZ_CP117710            23141 bp    DNA     linear   CON 25-MAR-2024
DEFINITION  Streptomyces sp. MMBL 11-1 plasmid unnamed1, complete sequence.
ACCESSION   NZ_CP117710
VERSION     NZ_CP117710.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MMBL 11-1
  ORGANISM  Streptomyces sp. MMBL 11-1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 398978)
  AUTHORS   Choi,S.S., Park,H.S. and Lee,H.K.
  TITLE     Whole genome sequence of Streptomyces sp. MMBL 11-1 from novel
            marine Actinomycets
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 398978)
  AUTHORS   Kim,E.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-FEB-2023) MMBL, Inha university, 105, Building C, 100
            Inha-ro, Incheon, Michuhol-gu 22212, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 03-SEP-2021
            Assembly Method                   :: BLASTN v. 2.7.1+
            Assembly Name                     :: De novo
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 99.91x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028622875.1-RS_2024_03_25
            Annotation Date                   :: 03/25/2024 07:47:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,554
            CDSs (total)                      :: 7,455
            Genes (coding)                    :: 7,322
            CDSs (with protein)               :: 7,322
            Genes (RNA)                       :: 99
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 78
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 57 of 134
            Pseudo Genes (incomplete)         :: 101 of 134
            Pseudo Genes (internal stop)      :: 16 of 134
            Pseudo Genes (multiple problems)  :: 36 of 134
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:00:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 143550
            Orig. end                         :: 166691
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP117710.1.
            Bacteria and source DNA available from professor Eung-Soo Kim
            (In-ha university).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23141
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..23141
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23141
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13141](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13141
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            78..572
                     /locus_tag="PSQ21_RS36035"
     CDS             78..572
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PSQ21_RS36035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_274036427.1"
                     /transl_table=11
                     /translation="MKDLSRACALRHDRAVFHGVLPLLRTPAVEALDRQRPIGILIDNS
                     GPWASSFADLQFTLNTLRGWLPPGSAIALTHTTDDATTLPRQHAQARGHRAAADLAAAS
                     SCSSRPLTRTQIRSLIEPWPLTEHGLLPTSAFLAQPSSSGPSARRKCGSYAAISLHAEA
                     T"
     gene            569..1435
                     /locus_tag="PSQ21_RS36040"
     CDS             569..1435
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF016550.4"
                     /locus_tag="PSQ21_RS36040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_274036428.1"
                     /transl_table=11
                     /translation="MTARISSEPDRELQPQPLRFLGPERDAVFFGTAQSPRVYEWMLGG
                     CENYEADRDLAHALLEVADWVKTSAQLNRDFQVRSYTWCREQGVRQYLELGCGYPHHPV
                     LYDVLGRQCRVVYVDRDPGVLAHARTDLDQDHDTTVVGADVLAMDELLNSDALRQAIDP
                     SQPVAVFLGDVLPWCPDDSAVDRAMAALRSWMPPGSFLVLTHFTDEFTPGQAAAVAATY
                     AAHGVQVRPRSREQIAALFGDFVHQGPGLCATGQWHRGSPQARRPPEGSAAFAGIAMKP
                     TAQGRNA"
     gene            1432..2136
                     /locus_tag="PSQ21_RS36045"
     CDS             1432..2136
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF016550.4"
                     /locus_tag="PSQ21_RS36045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_274036429.1"
                     /transl_table=11
                     /translation="MTPPDTTWDSDREAEYLAQEEYDQFLDLGCGIPYFFAIRDGKRSY
                     DEVEHVHEAVARFQPHAPVLYVGISPVAIGQLRACMDNDDNCTYVHGDIRHVATLLASP
                     QVTEHLDLTRPVAVLAHDVLSWMTLIEARETARGLRHGPPPGSALSITHPTDDLGLPMS
                     KLTPPCEEADVVYQPRPREHVEALLGGWPLLPPGLVPTGAWSPRHAGTEAPGDRSGAFA
                     AIAVKPASRPTC"
     gene            2153..3043
                     /locus_tag="PSQ21_RS36050"
     CDS             2153..3043
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF016550.4"
                     /locus_tag="PSQ21_RS36050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_274036430.1"
                     /transl_table=11
                     /translation="MSSMSLVPPRSPAPVNQPPHVSRVADYFTGGMDNLRADRELADRL
                     RVAAPWLPQSVRAHRAHTTHVVRHLASEGFHQYLDLGCGLPYAEQGDEALHPYDAARSI
                     LVDVHGAQADVRTVYVDNYGPAYGHANTILAEERGTLAVNADARNVAGLLALPSVTSKL
                     NLNRPVAVLAHDLLPWMGDHDAVDLLNDLRRLLPPGSALSLTHTASDLPPGPESEGKDC
                     IRMMSALYAEAGIDFHPRSAGHLRALLNRWSVQEPGVVRTELWGSGYGRFAQRPLTGAA
                     DFTGAYAAVALTTAP"
     gene            3064..3303
                     /locus_tag="PSQ21_RS36055"
     CDS             3064..3303
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019884676.1"
                     /locus_tag="PSQ21_RS36055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5999 family protein"
                     /protein_id="WP_274036431.1"
                     /transl_table=11
                     /translation="MSTNSTTPTSATACCRHMPLCPPADAPDREAARLTAHHPEQGWSL
                     LCNGVLLFEDTGELLPDGQIVNPHRSPVTTAAGR"
     gene            3452..4297
                     /locus_tag="PSQ21_RS36060"
     CDS             3452..4297
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF016550.4"
                     /locus_tag="PSQ21_RS36060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_274036432.1"
                     /transl_table=11
                     /translation="MSRTPDGPARPPRMPSESPVDDVARSQGRAQTARLYNHLLGGKTN
                     YQVDREAAASLREACPDLSLTVAAGQTYARAVAGHLTGLGVWQFLDLGTGIPLRPYLHE
                     TIESLADDARTLYVDNDPMAEAYGQSFLTGNGFHFLEADVRDPGGLLAAVRRHGGIDLE
                     RPVALFIHGLLDFLADEEEPHGIVQALLDGLAPDSYLSVTHHAADLTPDRAAVLVRAYQ
                     EHGIRFQPRTRDQVERFLSGLDAGTGLTTAHRWAPGPGRAPIPGGDDLVPLYAGVGRLP
                     "
     gene            4666..5640
                     /locus_tag="PSQ21_RS36065"
     CDS             4666..5640
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PSQ21_RS36065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_274036433.1"
                     /transl_table=11
                     /translation="MSQNPLLTPREAESVTLLARGLSVQEIDQELGIVTSSRLIAFAKA
                     KAIVSTQRALVYVSLAREWIPRPPAVLPPAQLSPVEELVWAGLRLDVLDGQLPGALSQL
                     AGTTKVQVTTTLKALVKQQQLNHCGLIRHAYAIGLLSGREGTDVPPLPSRLAPPPQALT
                     VPWQRCPAPPQSGLTGGSARRSGPPETGDAVGTGTATEAVVSVAQAVRTGEDFDVVRVS
                     PEVCGQLLAGLPPGERGPVVCRVESATALLFLPPAVLPDGWRARHGRLWARGATVQLPP
                     DNRPSADGSYWAVPRRAPLWSPDRLEDLLNNLPGPLPAQPGAV"
     gene            5865..6842
                     /locus_tag="PSQ21_RS36070"
     CDS             5865..6842
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PSQ21_RS36070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_274036434.1"
                     /transl_table=11
                     /translation="MTPDIQLTARQREIAERLVTGWMPDRNESASGRTIDQIQASLGVL
                     TVRAACFRLLTLGLVPAPAPAGALDLDPVTRTAWEALRFDLLDVDLIPTVATGLSHSDD
                     PRASAHAVDSALNQVAQRFTTTRHGLIRLGLAHHVLFADQNVKPPAHQFAAPTPPGTGT
                     WDATPAQRRVLALRASGRDVAACAAADGTTIDAVTGRLNAAKRMAGGVRTPRALIHRAL
                     CDGVLQRPAPQRETDPSPQKQAVWRHFVLDEPEPALASRTATHTGLSMNIVDRWTRSLR
                     TRYRDDCAVVYEGWRYGVLDAGTPTDQTCCAVTGLTTAHTGGVR"
     gene            6839..7690
                     /locus_tag="PSQ21_RS36075"
     CDS             6839..7690
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.3"
                     /locus_tag="PSQ21_RS36075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Scr1 family TA system antitoxin-like
                     transcriptional regulator"
                     /protein_id="WP_274036436.1"
                     /transl_table=11
                     /translation="MTLSSPGTRVVGACLRDARERRMMLPEESADALGIDVPALLAIEE
                     GHRRIKPDALDTLTDLYRYPGTQALRRLLAQHLDHAGVVRDQEPDHAARLAACVDSASG
                     VRWQSTVVLPGPLQTPAYAQAVGAVPVTRPGAPRQPASSAVYLVDERVIQRSSDDAALM
                     AEQLEHLLRLLDSGTDIRVLPATCPVPQPAGHLVELHLPKGPVWARPGPDRVDYCATHG
                     FADAITNTLSGTDPGFSWEALSRAAAAHRALAPSPRRALSPSGNPPTPADRPATSSARR
                     AP"
     gene            7687..8586
                     /locus_tag="PSQ21_RS36080"
     CDS             7687..8586
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012610.4"
                     /locus_tag="PSQ21_RS36080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_274036437.1"
                     /transl_table=11
                     /translation="MTAHGTSRAQVADQAAMRDVHDRITGGYYVPGSKLTLRELSASTG
                     HDFSALRGALDHLTTTGLVTSRGRIADPRPDYRAERARALLSGMIERGAWPADTVLPAR
                     LVLGRLLLTEPAHLTQALGALADDGVLRMEPKGPPRVLPAPAGSPARAPWPPGETDVLD
                     ALPSNTLPGAAHDADSLHLVAHAVRERYKDGVCLPSEAMTMQEGRQAETVHRLVTQAFA
                     HTSGQATTQSPTVRSTAAQVMACHALPRNGPLYERLYRITVLATTLAHLADALAKPGPR
                     HVPTSAPRAWPIHAPEGP"
     gene            8762..9604
                     /locus_tag="PSQ21_RS36085"
     CDS             8762..9604
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PSQ21_RS36085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_274036438.1"
                     /transl_table=11
                     /translation="MKTHIVHQAGSRFDELAQRIETLVAKAAPLVEEVTQLRLPDALVI
                     RTMTWRKRRRVMSRHARQVLRAEAYELRPPLSSIRAAKGDMRAARAAMRTHWMGMGAET
                     VDLRGRAEILLLPQALREAGRLHDDDSLLQVFAHELTHVAQWKYAGEDAWRRALTLFPA
                     ERGITDRDYSFLFEGHAYWTDAQVTAKILGAPVPIAEISPHSTLRYRAMAEAPEAEAAV
                     RHIRTARDSVSAAISAHGLDLINDALRDPKLVPLRSETSTPEAWSARLTDKRAEQSRR"
     misc_feature    9875..9891
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 23.28"
                     /tool="antismash"
     misc_feature    9921..9935
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            10001..13141
                     /locus_tag="PSQ21_RS36090"
     CDS             10001..13141
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="PSQ21_RS36090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_274036439.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 5.5e-149,
                     bitscore: 491.7, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 3.3e-08,
                     bitscore: 28.8, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRPPSYQAQRPILVRAPLHADLSIPQLPDLREDGHAAAAARRTW
                     LEEVWADDRFAEAVRHASPSLGSTIDTLAGARTADDPAVRQAVRALAGYALRAVHRPTP
                     FGLFAGIAEGSFGEAARADWGTGHTVVASAGAQWMADIVDRLAQDPEVRTRVSVVASNG
                     ARVSGSRLVVPWRRRRKGEDDSAVRYTTLRHTEVVRALLALTASPLPYREAVGKAAAES
                     GCDAGQTAAVLDQLIEQHAVLTMLTPPTTVTDQLGHLRTVLRDAGVHPSAAKGLAGALQ
                     DIGGVLEQHNRPGCRVEEARELRTRLRKRMLPWSPVSDQLDLDVRLDADVTLPRAVAWE
                     AERAAGLVARLSAEPDGTAAWTRYRRRIADRYGPGVLVPVADLLDPATGLGLPEDFHGT
                     PRAPAPGLSHRDAVLMAHAQQAAAEHRELVLDEVLINELTRDHPVATGPATLELKTSIH
                     AASKQDLDAGRFTLLIDRVSRGWGHFSGGRFARLLHHRSPAMPGGLLATLMDRPTATRG
                     AVPAQLAYPGLQRSHPVVTTTPRLGPDLITLSEPSAPADITAPPIALDDLAVLLDPAAD
                     RLHLVRISTRRIIEAFTPHPLQWEFLTPTVGRFLDELTRGQAARVTDTFGVLSTWDWGA
                     ARLLPHQPRVRAGRTILSPATWDLSHAQLPNTNTSGRHWDDAFRALRERWAIPDRVHVQ
                     WFDQRRTLNLTDATHRTLLREELTRDRPAGRAQLIEAEPAEAYGWCGGRPHEIVTLLAS
                     RTQAPEPAAVRTAPVARRSDVGMPGASAYLRVRLHTGHPQIHPLLTEHVPDLMADLDGP
                     AWWAARDDDYPGRAELTIRMPSPETAAPALGVVGRWAEVLTRTGVLSSLAVLPYRPRPG
                     IWGEGPVMTAAENVLAADTACTVHQHAHVTGEDPRVLAALNVLAITAGLTGSHRAGLTW
                     IVAQPKPAATQPLARALDQATRARVHTQPLVDSLSVLPGGRRLVNQLWPQRDTALLAYA
                     TQLSESDRCRDTVLHELVRAHLRLALHSSADRATAWRLARSAALGHLATAQEMECDQ"
     aSDomain        10472..10747
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_PSQ21_RS36090_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.40E-09"
                     /identifier="RREFam001.1"
                     /label="PSQ21_RS36090"
                     /locus_tag="PSQ21_RS36090"
                     /protein_end="249"
                     /protein_start="157"
                     /score="28.8"
                     /tool="antismash"
                     /translation="VVASNGARVSGSRLVVPWRRRRKGEDDSAVRYTTLRHTEVVRALL
                     ALTASPLPYREAVGKAAAESGCDAGQTAAVLDQLIEQHAVLTMLTPP"
     gene            13153..13809
                     /locus_tag="PSQ21_RS36095"
     CDS             13153..13809
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019765090.1"
                     /locus_tag="PSQ21_RS36095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_274036440.1"
                     /transl_table=11
                     /translation="MKGPGRSAAPVGEPILVNVAAADALSRAGLVAQLRPHPEVCVLDE
                     GDSTEAAVLVLVADTVDENVRVLVLRTSRTTTMRTLLVVTSIDEQHLVSAVESGVTGIV
                     RRADASPEHLIQAIRSVARRDGHLPGDLLGQLLTTVGTVQKTLLGPRGLYFAGLNDRER
                     NVLRLLADGHDTSDVAESLGCSQRTVKKILTDLMHRLNLRNRTQAVAYALRNDLI"
     gene            13920..16319
                     /locus_tag="PSQ21_RS36100"
     CDS             13920..16319
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016724.4"
                     /locus_tag="PSQ21_RS36100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_274036441.1"
                     /transl_table=11
                     /translation="MTERPSANVVSSQMAAHAGPPAPSASRPLWPHQRDAVNDAVGELK
                     VADRATVVMACGTGKTRVAAETALRLAGARSGGFLYTAPNLELLSQTLAEWRTTFGHEP
                     WGRIIAVCSDKDLDGKQAAELHAGRAAVTTQPAELAALAPKTGRFTILSTYHSLGVVGA
                     AQRHHEMPMIDLLAIADEAHRTAGAVHKPWTAFHDDTRIRAARRLNLTATPRIVAGGDQ
                     VISMSDERVYGRTCHTLPFGRAIELGLLANYRVVVPVIATDQLREAARVLRGRSDFFRI
                     GKTAMSPDALATQIAVLRAARTYGVQRMITFHNRVTHARWFATTLPLTADLLPPGERPE
                     HVKAGHVHGGQTLAERRAVLKGLRSDGDEFCVVCNARVLGEGIDLEVDGIAFIDPRKSV
                     IDTAQAVGRALRLGRRGAAKTATILIPVHLREGQDPETALESSQFGPVWEVVRALASHD
                     EVLAGNLKDLRRRIGIYGNLRDPARRSELPEWLDVTGVPVPAGFAEAITVHLVRSSTTP
                     WEEFLGACSAFYAEHNHLDVPPQYTTPGGLPLHEKLHHQRQRYRRGVLDPRRKEELEKF
                     GIVWEVLDSKRQRFRDELIRFRREHGHLRIPKGFRTGGDNPMNLGSAVGTVRARYAAGK
                     LSTEEIDFYESLGMIWRVTEADRAQFLEDLRQYKDQHGHLDIPVKCVLPGAPPRKLGQQ
                     VSILRSQFVRGELPPEMMTALKEIGFIENVYEFRYQRYLDALILFKEENGHVRLPPGYR
                     TPPPGDLALYEWLQNRKSDYTKGKLPPERIRDLVDLGCEWHKGGMA"
     misc_feature    16125..16127
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16316..18496
                     /locus_tag="PSQ21_RS36105"
     CDS             16316..18496
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PSQ21_RS36105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_274036443.1"
                     /transl_table=11
                     /translation="MNPNGRIPANRGVGLPGPYSATTTGRSGALSAVTGPGATAANTIN
                     DGVFQGPVVLAGTVTGGIHHHAAPPLKVAACQLPRLAPYFTNRCTELAALEAARATGTQ
                     MVVLSGIAGVGKSALAAQWLHTQQDTADAQLHADLTPPLAAGSLPEAVLAPWLRALGVE
                     RASGRGAELVGLWRSLTAQREVHVLIDGARDAEQVRPLLPSGTRSFALVTSRRLLWELS
                     ADGALLLPLGPLAPRDAVTLLCAAAGVPEAAVAEERAAAAAAWAASCAHLPLPLVLTGA
                     RLRSRPARPFAPPRAGVASPQPQEHALVAITTALDASYAELEAEAQRLYRTLGALPAPT
                     VDADLAAAVCELPVATAGWLLEILAEERLLDPGPGDGSAARYRMNAALRDHAWSKAKAE
                     PDAAEQREAALRRLCMWTLDLLRHAQKLLTPAQATLLTPRQLPDSPFTDGDMALAWLDD
                     QEENLLPVVAAAAAERWDELTYQLVDAWWPYFLLRHPFDLWLPAHELGVAAARRAGNAP
                     VLRQLLASWAIGISASGHPADAIPLHEELLHAARGAGDVRDEGQALLGLGGCHLDAGHP
                     APARLHLREAIVRWESCGYTRGIGLAEITLGQVCLADENPAAATVHLLSAYGRLTEIQE
                     HFEAGRALALLGHARSTGGNSAEGISDLERALDLVAMSALWRARTLEWLGDAHQHRGDE
                     ATARTCWRSAADAFATIRRDDAVRLWAKATGR"
     misc_feature    17477..17479
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18493..20739
                     /locus_tag="PSQ21_RS36110"
     CDS             18493..20739
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018520065.1"
                     /locus_tag="PSQ21_RS36110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_274036445.1"
                     /transl_table=11
                     /translation="MTPAAGSGSHTETRNTVTGDATVYGAVIQAGSITGGMHIHPGSPA
                     LPIPRQLPPVPATFTDRQESVDALGDWIREHSAYVRAIAVHGTAGIGKTTLAARLLDGL
                     RDQFPAGQLYADLRGARRPGHASSLTDVLGYLLRSLYTGRLPSGLDERGALWRSVTAGC
                     TQPLAVLLDNVVLAEQVRALMPGGRGHLVVVTSREPLSDLVRDGVLLHQLAPLAPPAAL
                     QYLARLAGQERIDVNPAAARRITELSAGLPLALGLVGGELAAHPNRDLGAMANVLEHAH
                     HRTRTTSHPPSTTGIAVTSSLHLAYASLPPASARLYRNLGPLNFTPDIDTALTAALADL
                     TPQTAAHQLQTLHESGLLTVRSESDPVRGTVYTLHDEARAHARGRTEDVATDGEREERA
                     RRVLDYLLHNLTAAERELTPEHRRLARTYLYPPPGPAPFTDAAGATAWLHAYAEHFLPA
                     VRAAAAAGLHATTWQLTHALWCWLRLSHDYAAWSESHALAADAARADGNALAQCEILGT
                     WGIGLRNEHRYDTAIEKFTAVLDLARDGGDQRGAAQALHEIGATHLAVGRRDLAGRFLS
                     EARQLREGLLNAAEDPAEQRAHRRSVALTDICLGELAIALGQGEVAVARLTGARDSLLD
                     IPDPLDAARACAYLGRAHALTRDYDAAQDQGRRAVHECTGLGTYRWTARSTEMLGRTVL
                     EAGRHAEARILLQQARGLFAPISPADTERVDVLLHHLDSTRPPERCPLREKHES"
     gene            20854..22827
                     /locus_tag="PSQ21_RS36115"
     CDS             20854..22827
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PSQ21_RS36115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_274036446.1"
                     /transl_table=11
                     /translation="MHHHVGRLIANRYRITEPASPGDDAAGFLATDERQATEVTVLVRP
                     YALPEVLIPDDSHRYGPRTDRAPWEAAKITDIVRVVTQLPEHKHVGVLRDAAADGDLVW
                     LVQERIAPGEPLSRTLTRGPADPHRAAEIAHDLLRGLRHLHRRGWHHGNITPQTVWLDD
                     YGNAILTGLDQAVLDDLVCGIPRSMPQPPAPPPAVTGPGFRTPPQPAATAPPVAVRPGA
                     IGGIAGGVRADAFRGTGAGPRAAVARPRPHTEAAPPEPATPAARPPLTPLEAGRAQQLR
                     MITVGYVVERWAPEQALLLSDATPVIPPVGPSTDLWALGALLFRAVTGGPPYPELHDTA
                     ELLDMVRSEPPAYAEDTGALRPLIEQLLCSDPLKRPSTEELLRWIASIARDAPEPTTVA
                     PAREPAPPPGTSLVLRFRGHLVRRSRKAMPPSRPVRRRARHRRPDSRLRIPPRTVCLIT
                     LTAATALTFSVYTSTRAPGPNHAPADDRHLPPQPSAPGPSPDTQPVVRDPAGFSIATAP
                     GAHRHATPRTVEYRHNGITITVVPGHDTLHPSESPLDYQRRQPELAAVRADPESTASGL
                     RLTTIGQGGTIAEGTYRFSPDVGPPTYLRNRVNVLGGKLHVLLVSGPVARHEQIDAAYL
                     QAAESYEPTLLEQQPARRAAPS"
     misc_feature    22898..22912
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.41"
                     /tool="antismash"
ORIGIN
        1 ccgccttccc cgcccgtcgt ccatgcaccg gcgtcccgga cgccacattc gtccatgttg
       61 cgtctcccgt gtctccggtg aaggacctca gccgcgcgtg cgccctgcgg cacgaccgcg
      121 ccgtcttcca cggggtgctg ccacttctgc gtacgcccgc ggtggaagcc ctggaccggc
      181 agcggccgat cgggatcctt atcgacaatt ccggtccctg ggcgagcagc ttcgccgacc
      241 tccagttcac cctgaacacg ctgcgcggct ggctgccgcc cggcagcgcg atcgccctga
      301 cccacaccac ggacgacgcc accaccctcc cccgtcagca cgcccaggcc cgtggacacc
      361 gtgccgcagc cgatctcgcg gcggcatcca gctgttcatc gaggcctctg actcgcaccc
      421 agatccgcag cctcatcgaa ccctggccac tgaccgagca cggtctgctg cccaccagcg
      481 cgttcctcgc ccagccttcc tcctctggcc cgtccgcccg ccgcaagtgc ggctcctacg
      541 ccgccatctc cctccacgcg gaggcgacat gacagcccgc atctcctccg agcccgaccg
      601 ggagctccag ccccagccgt tgagattcct gggccccgaa cgtgacgccg tgttcttcgg
      661 caccgcgcag tccccgcggg tgtacgagtg gatgctcggc ggctgcgaga actacgaggc
      721 cgaccgggac ctggcccatg cgctgctgga agtggccgac tgggtcaaga cctccgcgca
      781 gctcaaccgg gacttccagg tccggtccta cacctggtgc cgtgagcagg gggtgcggca
      841 gtacctggag ctgggatgcg gctatcccca ccaccccgtc ctctacgacg tcctcggccg
      901 gcagtgccgg gtcgtctacg tcgaccgtga cccgggcgtc ctcgctcacg cccggactga
      961 cctcgaccag gaccacgaca ccaccgtcgt cggcgcggac gtcctggcga tggacgagct
     1021 gttgaatagt gacgccctgc ggcaggcgat cgacccttcc cagccggtgg cggtgttcct
     1081 cggcgacgtg ctgccctggt gccccgacga ctcggccgtc gaccgggcga tggcggccct
     1141 ccgttcgtgg atgccgcccg gcagcttcct ggttctcacc cacttcaccg acgagttcac
     1201 gcccggccag gccgcggccg tggccgccac ctacgccgcc cacggtgtgc aggtgcgccc
     1261 ccgttcgcgg gagcagatcg ccgccctgtt cggtgacttc gtccaccagg ggccgggcct
     1321 gtgcgcgacc gggcagtggc accgcggcag cccccaggcc cgccgtccgc ctgagggctc
     1381 cgccgccttc gccgggatcg ccatgaagcc gacggcccag gggaggaacg cttgacgccg
     1441 cccgacacca cgtgggactc cgaccgggag gccgagtacc tcgcgcagga ggagtacgac
     1501 cagttcctgg acctcgggtg cggcattccg tacttcttcg cgatacggga cgggaagcgc
     1561 tcgtacgacg aggtggagca tgtccacgag gccgtcgccc gcttccagcc gcacgccccg
     1621 gtcctctacg tcggcatctc ccccgtcgcg atcggccagc tgcgtgcctg catggacaac
     1681 gacgacaact gcacctacgt ccacggcgat atccggcacg ttgcgaccct gctggcctcc
     1741 ccgcaggtca cggaacacct ggacctgacc cggccggtag cggtgctggc ccacgacgtc
     1801 ctgtcctgga tgaccctcat cgaagccagg gagaccgccc gcgggctcag gcacgggccg
     1861 ccgccgggca gcgcactgtc gatcacgcac ccgaccgacg acctgggcct gccgatgtcg
     1921 aagctcacgc ccccgtgcga agaagcagac gtcgtctacc agccgcgtcc ccgggagcac
     1981 gtcgaagcgc tgctcggcgg ctggcccctg ctgccgcccg gtctggtgcc cacaggggcc
     2041 tggtcaccgc gccacgcggg gaccgaagcg ccgggggacc gctccggcgc gttcgccgcg
     2101 atcgccgtca aacctgccag ccgacccacc tgctgaagga acaccacctc agatgtccag
     2161 catgtcgctc gtcccgcccc gctctcccgc cccagtaaac cagccgcctc atgtctcgcg
     2221 cgttgccgac tacttcaccg gcggaatgga caacttgcgt gccgaccggg agcttgccga
     2281 ccggttgcgc gtggcggctc cgtggcttcc gcagtcggtg cgggcccacc gcgcgcacac
     2341 cactcacgtg gtgcggcacc tggcgagcga gggctttcac cagtacctcg acctcgggtg
     2401 cggcctgcca tacgccgagc agggagacga ggccctccac ccgtacgacg cggcccgctc
     2461 gatcctcgtc gacgtgcacg gcgcccaggc cgacgtccgc acggtgtacg tcgacaacta
     2521 cggaccggcc tacggccacg ccaacacgat cctggccgag gagcgcggaa ccctcgccgt
     2581 gaacgccgac gctcgcaacg tcgccggcct gctggcgctc ccctccgtga cctcgaagct
     2641 caacctgaac cggcccgtcg cggtcctggc gcacgacctg ctgccctgga tgggcgacca
     2701 cgacgcggtc gacctcctca acgacctgcg ccgactcctc ccgcccggca gcgcgctgtc
     2761 cctcacccac accgcgagcg acctgcctcc cggccccgag agcgagggca aggactgcat
     2821 ccggatgatg tcggccctct acgccgaggc gggcatcgac ttccaccccc ggtcggccgg
     2881 gcacctgcgg gccctgctga accggtggtc cgtacaggag cccggtgtcg tacgcaccga
     2941 gctgtggggc tccggatacg gccggttcgc tcagcggccc ctcacgggcg ccgccgactt
     3001 caccggcgcc tacgccgccg tcgccctgac caccgcaccc tgacgccgaa aagggccacc
     3061 ctcatgtcca ccaactccac gaccccgacc tccgctacag cgtgctgccg gcacatgccg
     3121 ctctgcccgc ccgccgacgc accggaccgc gaggccgcgc ggctgaccgc gcaccatcct
     3181 gagcagggat ggagccttct ctgcaacggc gttctgctct tcgaggacac cggagaactg
     3241 ctgcccgacg gacagatcgt gaaccctcac cgcagcccgg tcacgacggc ggccggccga
     3301 tgacggcggc ccaccgcctt ggcgcagccc tcccgggaca ctcggctggt acgggatcag
     3361 gacgctgcga gcgtccgcgt acgaggtgcg gcgagggggc gctcccgcgt gcccgtggag
     3421 cagccggtcg acttcagcgg gaggaccggc gatgagcagg acgcccgacg gcccggcgcg
     3481 accgcctcgg atgccctccg agtcaccggt cgatgacgtc gcccgcagtc agggtcgggc
     3541 acagaccgcc cggctgtaca accatctgct gggcggcaag acgaactacc aggtggaccg
     3601 ggaggcggct gcgtcgctgc gggaggcctg ccccgacctc tccttgaccg tggcggccgg
     3661 ccagacctac gcccgggccg tcgccggtca cctcaccgga ctgggagtgt ggcagttcct
     3721 cgacctcggt accgggatcc ccctacggcc ctacctccac gagaccatcg aaagtctcgc
     3781 cgacgacgcc aggaccctgt atgtcgacaa cgaccccatg gctgaggcgt acgggcagag
     3841 ctttctgacc gggaacggct tccacttcct ggaggccgac gtgcgagacc ccgggggctt
     3901 gctcgcggca gtgcggcgtc acggcgggat cgacctggaa cgcccggtgg cgttgttcat
     3961 ccatggcctt ctcgacttcc tcgccgacga ggaagaaccg cacggcatcg tccaagctct
     4021 gctggacgga cttgcgccgg actcctatct cagcgtgacg caccacgcag ccgacctcac
     4081 ccccgaccgg gcggccgtcc tcgtgcgcgc ctaccaggag cacggaatcc gtttccagcc
     4141 gagaacccgg gaccaggtgg agcggttcct cagcgggctc gacgcaggta ccggtctgac
     4201 gacggcccac cgctgggctc ccggcccggg ccgcgccccg atcccgggtg gcgacgacct
     4261 ggtgcccctg tacgccgggg tggggcgcct cccctagccc tccgccccgt cgaggaacgc
     4321 tccgcagcgc ccagctggcc agcccgcgca caccctcacc ctcaactcga ccgttatgca
     4381 ccaaataggg aatgatatgg atcgctttgc tgctccggcg aacctggctc ctccagcggc
     4441 cgcgcccgcc gagccgcagt gccgcgacgt ccccgtgccc ctgcgctcgc gccatgtccc
     4501 cttcattgtg gagcgagcgc tgtcggcggt ggtcgcgacc cggtacgtgt gcgacctccg
     4561 gcgcgtgtcc gaggccgacc cctcccacat cagggacctt tgccgcggtg gcggtgtccc
     4621 ggaccgggcc gacagggaac gctgtgccgt ctccgggagg tcggagtgag ccagaacccc
     4681 ttgctcactc cgcgggaagc ggagagcgtc acgctgctgg cccgtgggct gagcgtccag
     4741 gagatcgacc aggaactcgg catcgtgacc tcgtcacgtc tgatcgcctt cgccaaggcc
     4801 aaggcgatcg tctccaccca gcgcgccctg gtctatgtca gcctcgcccg ggaatggatc
     4861 ccgcgcccgc ccgccgtact gccgcccgcc cagctgagcc ccgtggagga actggtctgg
     4921 gccgggctgc gtctcgacgt cctggacggc caactccccg gtgccctctc ccagctcgcg
     4981 ggcacgacca aggtccaggt caccaccacg ctgaaggcac tggtgaagca gcagcagctg
     5041 aatcactgcg gcctcatccg ccatgcgtac gcgatcggcc tgttgtccgg acgtgagggc
     5101 accgacgtac caccgctgcc ctcccggctc gcgcccccgc cccaggccct gaccgtgccc
     5161 tggcaacggt gcccggcccc gccgcagagc ggcctcaccg gaggcagtgc ccggcggtca
     5221 ggcccgcccg aaaccggcga cgccgtcgga accgggacag ccacggaagc ggtcgtgtcc
     5281 gtcgcgcagg cggtgcggac cggggaggac ttcgacgtgg tccgggtcag cccagaggtg
     5341 tgcggccaac tcctcgcggg cctcccgccc ggggagcggg ggccggtggt ctgccgcgtg
     5401 gagtccgcca ccgcgcttct tttcctcccc ccggccgtgc tgcctgatgg gtggcgtgcc
     5461 cggcacggcc gactgtgggc ccggggtgcc acggtgcaac tgccgccgga caaccgcccg
     5521 tccgccgacg gctcctactg ggcggttccc cgccgagcgc cgctgtggag cccggaccgc
     5581 ctggaggacc tcctcaacaa cctgccgggc cctctcccag cacagccggg agcggtgtga
     5641 ccctccccaa agaaccgaac gggccgacgg cagcttccgc cgctgccccc acgccgaccc
     5701 acgatcggac gtccgccatg gacctcacac cggccccgcc gggccacccg ccgcaccctc
     5761 ccaccgtccc ggcttcgccg cctgccgccg cgccgtcacc ggtgccggga tgccgcgcga
     5821 gatcactgcg ggagcgggat ccggtgtcgg ggatccagca caggatgacg cctgacatcc
     5881 agctcaccgc gcggcagcgg gagatagccg aacgcctggt cacggggtgg atgccggacc
     5941 ggaacgagag cgcctccggc cggacgatcg accagatcca ggcgagcctg ggcgtgctca
     6001 ccgtacgcgc ggcgtgcttc cgcctcctga cgctcggcct ggtccccgcg cccgcccccg
     6061 ccggcgccct ggatctggac ccagtcaccc gcacggcgtg ggaggccctg cgcttcgacc
     6121 tcctggacgt cgacctgata ccgaccgtgg ccaccgggct cagccacagc gacgatccgc
     6181 gggcgtccgc gcatgccgtg gacagtgccc tcaaccaggt ggcacagcga ttcacgacca
     6241 cccgccacgg gctcatacgc cttggcctcg cccaccacgt gctcttcgct gaccagaacg
     6301 tgaagccacc ggcgcaccag ttcgcggctc ccacaccacc gggcacggga acctgggacg
     6361 ccacgcccgc tcaacggcgg gtgctggcac tgcgcgcctc gggccgggac gtggccgcct
     6421 gcgccgctgc tgacggaacg acgatcgacg ccgtcaccgg ccgcctcaac gccgccaagc
     6481 ggatggcggg aggggtgcga accccccggg cgctcatcca ccgcgcgctc tgcgacggcg
     6541 tgctccagcg acccgccccc cagcgggaga cggacccctc accccagaaa caggccgtgt
     6601 ggcggcactt cgtcctcgac gaaccggagc ccgccctcgc ctcccggacc gccacgcaca
     6661 ccggcctgag catgaacatc gtcgaccggt ggacgcgcag cctgcggacc cggtaccggg
     6721 acgactgcgc tgtcgtctac gaaggctggc ggtacggcgt cctcgacgcg ggcacgccca
     6781 ccgaccagac ctgctgcgcc gtcaccggac tgacgacggc gcacaccggg ggtgtccggt
     6841 gacactgtcg agcccgggaa cccgtgtcgt cggcgcgtgt ctgcgcgacg cgcgcgagcg
     6901 gcgcatgatg ctgcccgaag agagcgccga cgccctcggc atcgacgtcc cggcactgct
     6961 cgcgatcgaa gagggccacc gccgcatcaa gcccgacgcc ctggacaccc tcaccgacct
     7021 ctaccggtac cccggaacac aggctctgcg ccgactgctg gcgcagcatc tcgaccacgc
     7081 gggcgtcgta cgggaccagg agcccgacca cgccgcgcgg ctcgcggcgt gcgtggacag
     7141 cgccagtggc gtccggtggc agtcgaccgt ggtcctgccc ggcccgttgc agacccccgc
     7201 ctacgcacag gctgtcggcg cggtgcccgt cacccggccc ggcgctcccc ggcaaccggc
     7261 cagctcggcg gtgtacctgg tggacgagcg ggtcatccag cgcagcagcg acgacgctgc
     7321 cctcatggcg gagcagctgg agcaccttct gcgcctgctg gacagcggca cggacatccg
     7381 cgtcctgccc gccacctgcc ccgtcccgca gcccgccggc cacctcgtcg aactccacct
     7441 gcccaaaggg ccggtctggg cccgcccggg ccccgaccgg gtcgactact gcgcgaccca
     7501 cgggttcgcg gacgccatca ccaacacgct gtcgggcacc gacccgggct tctcctggga
     7561 ggccctctcc cgcgcggccg ccgcccaccg cgcgctcgcc ccctccccgc gaagggctct
     7621 atccccctcc ggcaacccgc ccacgcccgc agaccgcccg gccacctcct ccgcccggag
     7681 ggcaccatga ccgcccacgg cacctcccgc gcgcaggtcg ccgatcaggc tgcgatgcgt
     7741 gacgtccacg accggatcac cggcggctac tacgtgcccg ggtccaagct caccctgcgt
     7801 gaactctccg cctccaccgg acacgacttc tccgctctgc ggggggccct ggaccacctg
     7861 accactaccg ggctggtcac cagccgaggg cggatagccg acccccggcc cgactaccgc
     7921 gcggaacggg ccagggcact cctgtccggg atgatcgaac ggggtgcgtg gccggccgac
     7981 accgtgctgc ccgcccgcct cgtcctcggc cggctcctgc tgaccgagcc ggcccacctc
     8041 acccaggccc tcggcgcact ggccgatgac ggcgtcctgc gcatggagcc caagggcccg
     8101 ccgcgcgtac tcccggcccc cgccggttcc cccgcccggg ccccgtggcc gcccggcgag
     8161 acggacgtgc tggacgccct gcccagcaac acgttgcccg gagccgccca cgacgcggac
     8221 tccctccacc tcgtcgcgca cgcggtccgc gaacggtaca aggacggcgt ctgcctcccc
     8281 tcggaggcaa tgaccatgca ggagggccgt caggccgaaa ccgtgcaccg cctcgtgacg
     8341 caggctttcg cgcacacctc aggccaggca accacacagt ccccgactgt gcggtccacc
     8401 gccgcccagg tgatggcctg tcacgccctg ccccggaacg ggcctctcta cgagcggctc
     8461 taccgcatca ccgtgctcgc gaccaccctc gcgcacctcg ccgacgccct tgcgaaacct
     8521 ggcccacgtc acgttcccac ctccgcgccc cgtgcctggc ccattcacgc cccggagggc
     8581 ccatgagacc tctgctccgg gctccgccat cagcgcggcc gcggccggcc gacgcccaga
     8641 gccgcaacgg gatacaagcg gccggccttc gcattgaacc cgtcccgtac accgctccgc
     8701 cgaggcccct gtgcccggca ccggcatacc gacaacacat cgagaatcag gaagacatca
     8761 ggtgaagacc cacatcgtgc accaggcggg cagcaggttc gacgaactgg cccagcgcat
     8821 cgaaacgctg gtggcgaagg cagccccgtt ggtagaggaa gtgacccagc ttcgcttgcc
     8881 cgacgccctg gtgatccgga ccatgacgtg gcgcaagagg cgccgggtaa tgagccgcca
     8941 cgcccggcag gtgttgcgcg cggaggccta cgaactccgc cccccgctca gcagcatccg
     9001 cgccgcgaag ggggacatga gggccgcccg ggcagcaatg cgaacgcatt ggatgggaat
     9061 gggcgccgag accgtcgacc tccgcggccg ggccgagatt ctgctgttgc cccaggccct
     9121 gcgggaagcc ggacgcctgc acgacgacga ctcgctcctt caggtcttcg ctcatgagct
     9181 gacgcacgtc gcccagtgga agtacgccgg ggaagatgcg tggcgccgcg cgctcacgct
     9241 gtttcccgcc gagcggggca tcacggaccg cgactactcc ttccttttcg aagggcatgc
     9301 ctactggacc gatgcgcagg tgaccgccaa gatcctgggc gccccggttc cgatcgccga
     9361 gatcagcccc cactccacgc tccgctaccg agccatggcc gaggcccccg aagccgaagc
     9421 ggccgtacgg catatcagga cggcccgcga cagcgtgtcc gccgccatca gcgcgcacgg
     9481 cctcgacctc atcaacgacg cgttgcgcga cccgaaactg gtgccgctca ggtccgagac
     9541 cagcaccccg gaggcctggt cagcgcgcct caccgacaag cgggccgagc agtcgcgacg
     9601 gtgaacgaga aacgccgagg cccgccgtgc cgacgactgg cgcaggcggg cgcaggcgcc
     9661 cttggagccg cagcctcagc acccccacag tccttcttcc aggagacccc tgtgtccaga
     9721 cgccgccccg ctgtcgaccg cccagcctca atcgaccccg aggcacctca cgcccggcac
     9781 cgtcgaccgg ccacattgct acccgcgtcc ccgccccagt caccgggacc acgctgggcg
     9841 gcgttcacga ccgccgtacg cgcgcatcgc cccgttgcac acgacttgga cgtccgcgag
     9901 ggcgaagtgc cgttcacggg cgacggcctc ggccacttct tttcccaccc ctgacacccc
     9961 accgatccgc ccgactcggc cgtcgacgcg aaggaccacg atgccccgac ctccctccta
    10021 ccaggcccaa cgccccatcc tggtgcgcgc gccgctccac gccgacctgt ccatcccgca
    10081 gctcccggac ctccgagagg acgggcacgc ggcggcggcc gcgcgccgca cctggctgga
    10141 ggaggtgtgg gcggacgacc ggttcgccga ggccgtacgg cacgcctccc cgagtctggg
    10201 cagcacgatc gacacactcg ccggtgcccg cactgcggat gaccccgccg tacggcaggc
    10261 agtgcgggcg ctggccggat acgcactgcg ggccgtgcac cggcccaccc cgttcgggct
    10321 gttcgccgga atcgcggaag gctcattcgg tgaagcggcg cgggccgact ggggcaccgg
    10381 gcacaccgtg gtcgcctcgg caggagcgca gtggatggcc gacatcgtcg accggctcgc
    10441 ccaggacccc gaggtgcgca cccgggtgag cgtcgtcgcg agcaacggcg cccgggtgag
    10501 cggaagccgg ctggtggtgc cctggcggcg gcgccgcaag ggcgaggacg actccgcggt
    10561 gcgttacacg accttgcgcc acacggaggt ggtccgcgcg ctcctcgctc tgaccgcgtc
    10621 cccgctcccc taccgggaag ccgtgggcaa ggccgccgcc gagagcggct gcgatgccgg
    10681 gcagacggcg gcggtgctgg atcagctcat cgaacagcac gccgtgctca ccatgctgac
    10741 gccgccgacc accgtgaccg accagctcgg ccatctgcgg accgtgctgc gggacgccgg
    10801 agtacacccg tcggcggcga agggcttggc cggggcgctg caggacatcg gcggggtgct
    10861 ggagcagcac aatcggcctg ggtgccgagt cgaggaggcc cgggaactgc gcacacggct
    10921 ccggaagcga atgcttccct ggagtccggt gtcggaccaa ctggacctcg atgtacgtct
    10981 ggacgccgac gtcaccctgc cccgtgcggt ggcgtgggag gcggagaggg ctgcggggct
    11041 ggtggcccgg ctgtccgccg agcccgacgg gacggccgcg tggacccgct accgtcgccg
    11101 gatcgccgac cggtacgggc ccggcgtcct tgttcccgtc gccgacctcc tcgacccggc
    11161 gacgggcctg ggcctcccgg aggacttcca cggcaccccg cgcgcacccg caccggggct
    11221 ctcgcaccgc gacgccgtcc tgatggccca tgcccaacag gccgccgccg agcaccgcga
    11281 actcgtcctg gacgaggtgc tcatcaacga actcacccgc gaccacccgg tggccacggg
    11341 gccggcgacg ctggagctga agacgtcgat ccacgccgcc agcaagcaag acctggacgc
    11401 gggccgcttc accctgctca tcgaccgcgt cagccgaggg tggggccact tctctggagg
    11461 ccggttcgcg cgactgctcc accaccgctc ccccgcgatg ccgggcggtc tgctcgccac
    11521 gctcatggac cgtcccaccg ccacccgcgg cgcggtaccc gcccagctgg cctaccccgg
    11581 gctgcagcgc agccaccccg tcgtcaccac gaccccccgc ctgggccccg acctgatcac
    11641 tctgtccgaa ccgtcggctc cagcggacat caccgccccg ccgatcgccc tcgacgatct
    11701 cgccgtcctc ctcgacccgg ccgccgaccg gctgcacctg gtccgcatct ccacccgccg
    11761 gatcatcgaa gccttcacgc cgcacccact gcaatgggag ttcctcaccc ccaccgtcgg
    11821 ccggttcctc gacgaactca cccgcggcca ggccgcccgg gtcaccgaca ccttcggcgt
    11881 gctgtcgaca tgggactggg gagcggcccg gctcctgccc caccagcccc gtgtccgggc
    11941 cggacgcacc atcctcagcc ccgccacctg ggacctgagc cacgcccaac tccccaacac
    12001 gaacacctcc gggcggcatt gggacgatgc gttccgcgcg ctccgggaac gctgggcgat
    12061 cccggaccgg gtccacgtcc agtggttcga ccagcgccgc accctgaacc tgaccgacgc
    12121 cacccaccgg accctgctcc gcgaggaact gaccagggac cggcccgccg ggcgggccca
    12181 gctcatcgag gccgaacctg cggaagcgta cgggtggtgc ggcggccgcc cgcacgagat
    12241 cgtcacgctg ctggcctccc gcacccaggc gcccgagccc gccgccgtgc gcaccgcgcc
    12301 cgtcgcccgg cgcagcgacg tggggatgcc cggcgcctcc gcgtacctgc gggtgcgcct
    12361 gcacaccggc cacccgcaaa tccacccgct gctgaccgag catgttcccg acctcatggc
    12421 ggacctggac ggacccgcgt ggtgggctgc ccgcgacgac gactaccccg gccgcgccga
    12481 gctgacgatc cgcatgccca gcccggagac ggccgccccg gccctgggcg tcgtcggacg
    12541 atgggccgag gtcctgaccc ggaccggggt gctgtccagc ctcgccgtcc tgccctaccg
    12601 cccccggccc gggatctggg gcgagggccc cgtgatgacc gccgccgaga atgtcctcgc
    12661 cgcggacacc gcgtgcaccg ttcaccagca cgcccacgtc accggtgagg acccccgcgt
    12721 cctcgcagcc ctgaacgtcc tcgccatcac cgccggcctc accggcagcc accgggccgg
    12781 tctcacgtgg atcgtcgccc agccgaagcc agccgcgaca cagccactgg cccgggccct
    12841 agaccaagcc acccgggcac gggttcatac ccagccgctc gtcgacagcc tctcggtcct
    12901 gcccggcggg cggaggctgg tcaaccagtt gtggccccag cgcgacacag cgctcctcgc
    12961 ctacgccacc cagctgtcgg aatccgaccg ctgccgggac acggtgctgc acgaactggt
    13021 gcgtgcccac cttcgtctgg ccctgcacag ctccgccgac cgggcaactg cctggcgcct
    13081 ggcccgctcc gccgccctcg gccatctcgc caccgcgcag gaaatggaat gcgaccagtg
    13141 aaggaatcag cgatgaaggg ccccggccgc tcggccgcac cggtcggcga acccatcctc
    13201 gtcaacgtcg cggcagccga cgcgctctcc cgggcaggac tcgtcgcgca gctgcgcccg
    13261 caccccgagg tatgcgtcct ggacgaggga gacagcaccg aagccgcggt gctggtcctc
    13321 gtcgcggaca ccgtcgacga gaacgtacgc gtcctggtac tccgcacgag ccggaccacc
    13381 acgatgcgca cgctgctcgt cgtcacctcg atcgacgaac aacacctggt cagcgcagtt
    13441 gaaagcggag tcaccggaat tgtccgccga gccgacgcct cccccgagca cctcatccag
    13501 gccatccgct ccgtcgcccg acgagacggt catctgcccg gcgacctgct cggacagctc
    13561 ctcacaaccg tcggcaccgt acagaagacc ctgctgggcc ctcgcgggct gtacttcgca
    13621 ggcctcaacg accgcgagcg gaacgtgctt cgcctgctgg ccgacggaca cgacaccagt
    13681 gacgtcgcgg agagcctggg ctgctcccag cgcacggtca agaagatcct caccgatctc
    13741 atgcatcggc tcaacctgcg caatcgcacg caggcggtgg cgtacgcgct gcgcaacgac
    13801 ctcatctaac cggaagcgaa aggaccacac ccgatgaccg gcgactcacc gccccccacc
    13861 gccctgcatc tgatcgttga gcgtctggcc gatggcgcct cccaggaagg atccgccctg
    13921 tgacggagcg tccgtccgcc aacgtcgtga gcagccaaat ggcggctcac gccgggcccc
    13981 ctgccccgtc cgcatcgcgg ccgctgtggc cccaccagcg cgacgccgtc aacgacgccg
    14041 tcggcgaact gaaggtcgcc gaccgggcga ccgtggtgat ggcctgcggc acgggcaaga
    14101 cccgtgttgc tgctgagact gccctgcgcc tggcgggtgc gcgtagtggt ggcttcctct
    14161 acacagcccc gaacctcgag ctgctctcgc agacgctggc cgagtggcgc accaccttcg
    14221 gccacgagcc gtggggccgg atcatcgccg tctgctcgga caaggacctc gacgggaagc
    14281 aggctgctga acttcacgcc gggcgagcgg cggttaccac ccagcccgcc gagctcgccg
    14341 ccctggcacc gaagaccggg cgcttcacca tcctcagcac ctaccacagc ctcggcgtcg
    14401 tcggtgctgc gcagcgtcac cacgagatgc ccatgatcga cctgctggca atcgccgacg
    14461 aagcccaccg tacggcgggc gcggtgcaca agccctggac ggccttccac gacgacaccc
    14521 gcatccgcgc agcccggcgt ctcaacctca ccgcgacccc ccgcatcgtg gccggcggtg
    14581 accaggtgat cagcatgtcc gacgagcggg tctacggccg gacctgccac acactgcctt
    14641 tcgggagggc catcgagctc gggctgctcg ccaactaccg ggtcgtggtg cccgtcatcg
    14701 ccacggatca gctgcgcgag gcggcccgtg tcctgcgagg acgcagcgac ttcttccgca
    14761 tcggcaagac cgccatgtcc cccgacgccc tggccacgca gatcgcggtc ctgcgggccg
    14821 cccgcaccta cggcgtccag cgcatgatca ccttccacaa ccgagtgacc cacgcacgct
    14881 ggttcgccac caccctgcct ctgacggcag atctgctgcc tcccggtgag aggcccgagc
    14941 atgtgaaggc cggacacgtc cacggcggac agacgctggc cgagcgccgg gccgtcctga
    15001 agggcctgcg ctcggatgga gacgagttct gcgtcgtgtg caacgcccgc gtcctgggcg
    15061 agggcatcga cctggaggtg gacggcatcg cattcatcga tccccggaag tcggtgatcg
    15121 acacagctca ggccgtcggg cgtgcgctgc ggctcggacg ccggggagcg gcgaaaaccg
    15181 ccaccatcct tatcccggtt cacctgcggg agggacagga tcccgaaacc gctctggagt
    15241 cctcgcagtt cggaccggtc tgggaagtcg tgcgcgctct cgcctcgcac gacgaagtgc
    15301 tcgccggcaa tctcaaggac ctgcgccgcc gcatcggcat ctacggcaac ctgcgcgacc
    15361 ctgcccggcg ctccgaattg ccggagtggc tcgacgttac cggcgtgccc gtgcccgcag
    15421 ggttcgccga agccatcacc gtgcacttgg tccgttccag tacaactccc tgggaggagt
    15481 ttctcggcgc ttgctcagcc ttctacgcgg agcacaacca tctggacgtt ccccctcagt
    15541 acacaactcc cggcggtctc cctttgcacg agaagcttca tcaccagcgt cagagatacc
    15601 gcagaggagt tctcgacccg cgacgcaaag aggaactgga aaaattcgga atagtttggg
    15661 aggtcctcga cagtaagcgc cagcgcttcc gtgacgagct catcagattc cgccgggaac
    15721 acgggcacct gcgcatcccg aagggtttcc gcaccggcgg tgataatccc atgaatctcg
    15781 ggagcgccgt ggggaccgtc cgagcccggt atgcagccgg gaaactctcc accgaagaga
    15841 tcgatttcta tgaatctctt ggaatgatct ggcgggtcac cgaggccgat cgagcgcagt
    15901 ttctcgagga cctgcgccag tacaaggacc agcacggcca tctcgacatc ccggtgaagt
    15961 gcgttctccc cggtgccccg ccacgcaagc tcggccagca ggtatcaatc ctgcgatcgc
    16021 agttcgtgcg cggtgagctg cctccggaaa tgatgaccgc attgaaagaa atcggattca
    16081 tcgagaacgt ctacgaattc cgataccaga ggtatcttga cgccttaatc ctattcaagg
    16141 aggagaacgg gcacgtaagg cttccccccg gataccgtac acccccgccg ggcgatctag
    16201 ccctctatga atggttgcag aacagaaaga gcgattacac gaagggcaaa cttccaccgg
    16261 agcgcatacg cgatctcgtc gacctgggct gcgagtggca caaaggaggc atggcgtgaa
    16321 cccgaacggc agaattccag cgaaccgggg ggtggggctg cccgggccgt actccgccac
    16381 gaccaccggg cggagcggcg cgctgtccgc cgtcacaggc ccgggcgcga cggccgcgaa
    16441 cacgatcaac gatggggtgt tccaggggcc cgtcgtactg gccgggaccg tcaccggagg
    16501 aatccaccac catgctgcgc cgccactgaa agtggccgcg tgtcaactcc cacggctcgc
    16561 accgtacttc accaaccggt gcaccgagct cgctgcgctg gaagcagccc gggccaccgg
    16621 cactcagatg gtcgtgctca gtgggatcgc cggagtcggt aaaagcgcct tggccgccca
    16681 gtggctgcac acccagcagg acaccgccga tgcccagttg cacgccgacc tcactcctcc
    16741 gctcgcggcc ggctcccttc ccgaggcggt gctggcccca tggctccgcg cgctcggggt
    16801 agagcgtgcc tcgggccggg gagcggagct agtcgggctg tggcgctcgc tgacggcgca
    16861 gcgggaggta cacgtcctca tcgacggtgc ccgcgacgcc gagcaggtcc gcccgctcct
    16921 cccctcaggc acccgctctt tcgccttggt caccagccgg cggctgctgt gggagctgtc
    16981 tgccgacggc gccctgctgc tgccgctggg cccgctcgcc ccgcgggacg ccgtcaccct
    17041 gctctgcgcg gccgccggcg tccccgaggc ggccgtcgcc gaggagcgcg cggcggcggc
    17101 cgcagcctgg gcagcgtcct gcgctcacct gccactgccg ttggtcctca ccggggcccg
    17161 gttgcgctcc cgccctgctc gccccttcgc cccgccccga gccggcgtgg cctcacctca
    17221 acctcaggag catgccctcg tggccatcac cacggcgctg gacgccagtt acgccgagct
    17281 ggaggccgag gcccagcgcc tgtaccggac gctgggtgcc ctgcccgccc ccacggtgga
    17341 cgcggacctg gccgccgccg tctgcgaact gcccgtggcc accgccggat ggctcctgga
    17401 gatcctggcc gaggaacgtc ttctggaccc cggtcccggg gatggctctg cggctcgcta
    17461 tcggatgaac gcagcgttac gggaccacgc ctggtcgaaa gcgaaggccg agcccgatgc
    17521 ggccgaacag cgcgaggcgg cccttcggcg gctgtgcatg tggacgctgg atctcctgcg
    17581 gcacgcgcag aagctgctca cccctgccca ggcgaccctg ctcacccccc ggcagctgcc
    17641 ggacagtccc ttcacggacg gggatatggc cttggcctgg ctggacgatc aggaggagaa
    17701 cctcctgccg gttgtcgcgg ccgccgctgc ggagcggtgg gacgagctca cctaccagct
    17761 ggtcgacgcg tggtggccct acttcctgct ccgccacccc ttcgacctgt ggctgcccgc
    17821 acacgagctc ggggtggccg cagcccggcg agcgggcaac gcgccggtcc tgcggcagct
    17881 gctcgcctcc tgggccatcg ggatcagcgc ctccggccac cccgccgacg ccatccccct
    17941 ccacgaggaa ctgctgcacg cggcgcgggg ggcgggcgac gtgcgggacg agggacaggc
    18001 actgctcggt ctcggcgggt gccacctcga cgccggccac cccgcgccgg cccgactgca
    18061 cctgcgggag gcgatcgtcc ggtgggagtc ctgcgggtac acccgtggga tcggtctggc
    18121 ggagatcacc ctggggcagg tctgcctcgc ggacgagaac ccggctgccg ccacggtgca
    18181 tctgctgtcc gcgtacgggc ggctgaccga gatccaggag cacttcgagg cagggcgggc
    18241 gctggccctg ctcggccacg cccggagcac cggcggaaac agtgccgagg gcatcagcga
    18301 cctggagcgg gccctggacc tggtcgccat gagtgccctc tggcgggcgc ggacgctgga
    18361 gtggctgggt gacgcacacc agcaccgggg tgacgaggcc accgcccgca cctgttggcg
    18421 ctcggccgct gatgcgttcg ccacgatccg ccgggacgac gccgtgcgtc tgtgggcgaa
    18481 ggcgaccggc cggtgacccc ggccgccggt tccggcagcc acacggagac ccggaacacg
    18541 gtcaccggcg atgcgaccgt atacggggcg gtcatccagg ccgggagcat caccgggggc
    18601 atgcatatcc accccggctc tcccgccctg cccattcctc ggcagctccc gcccgtgccg
    18661 gccacgttca ccgaccggca ggaatccgtg gacgccctgg gcgactggat ccgggagcac
    18721 tccgcctacg tacgggccat cgccgtgcac ggcaccgcgg ggatcgggaa gaccaccctg
    18781 gccgcacggc tcctggacgg cctgcgcgac cagttccctg ccggccagct ctacgccgac
    18841 ctccgaggcg cgcgcaggcc ggggcacgcc tcctcactga ccgatgtgct cggatacctg
    18901 ctgcgctcgc tgtacacggg caggctgccg tccggcctgg atgaacgggg ggcgctgtgg
    18961 cggtcggtga cggccgggtg cacgcagccg ctcgccgtcc tcctcgacaa cgtcgtgctc
    19021 gccgagcagg tccgggccct gatgccgggg ggccggggcc acctcgtcgt cgtcacgagc
    19081 cgcgagccgc tgagtgatct ggtgcgcgac ggggtgctgc tgcaccagct cgcccccctc
    19141 gcgccgccgg ccgcgctgca gtacctggca cgtctggccg gccaggagcg tatcgacgtg
    19201 aacccggcgg cagcccgccg gatcaccgag ctgtccgccg ggctgccgct cgcgctcggg
    19261 ctcgtgggcg gcgagctcgc cgcccacccg aaccgggacc ttggagccat ggccaacgtc
    19321 ctggaacacg cccaccaccg aacacgcacc acttcacacc cgccgtccac gacaggaatc
    19381 gccgtgacct cttcgctcca cctcgcctac gccagcttgc cgcccgcgtc cgcccgtctc
    19441 taccggaacc tgggcccgct gaacttcacc cccgacatcg acacggcact caccgccgca
    19501 ctcgccgacc tgacgcctca gaccgccgcg caccagctcc agaccctcca cgaatccggg
    19561 ctgctgacgg tgaggtccga gtccgacccg gtacgcggca ccgtctacac actccacgac
    19621 gaggcccgcg cccacgcccg cggccgcacc gaggacgtgg ccaccgacgg cgagcgcgag
    19681 gagcgggccc gacgggtcct cgactatctg ctacacaacc tcaccgcggc ggagcgtgaa
    19741 ctcacccccg agcaccgtcg cctcgcgcgc acctacctct accccccgcc cgggcccgcc
    19801 ccgttcaccg acgccgccgg ggcaacagcc tggctccacg cgtacgccga acacttcctg
    19861 cccgccgtac gggctgcggc cgccgccgga ctgcacgcca caacctggca gctcacccac
    19921 gccctgtggt gctggctgcg cctgtcccac gactacgcag catggtccga gtcccacgcc
    19981 ctggccgccg acgccgcccg cgcggacgga aacgccctgg cccagtgcga gatcctcggc
    20041 acctggggca tcggcctacg caacgagcac cgctacgaca cggcgatcga gaagttcacc
    20101 gccgtcttgg atctcgcccg tgacggcggg gaccagcgtg gcgcggcgca ggccttgcac
    20161 gagatcggcg ccacgcacct ggccgtcggc cgccgtgacc tcgctggccg gttcctgtcc
    20221 gaggcacggc agctgcgcga gggcctcctg aacgccgccg aagaccccgc tgagcagcgg
    20281 gctcaccggc ggtcggtggc actgaccgac atctgcctcg gcgagctcgc catcgctctg
    20341 gggcaaggcg aagtggcagt tgcccgactc accggcgctc gcgactcgct cctcgacatc
    20401 cccgatcccc tggacgcggc ccgcgcttgc gcgtatctcg gccgggctca cgccctcacc
    20461 cgggactacg acgccgcaca ggaccagggc cgccgagctg tgcacgagtg cacaggcctg
    20521 gggacgtacc gctggactgc gcggagcacc gagatgctcg gccgcaccgt cctggaagcg
    20581 ggccgccacg cagaggcccg catcctgctc cagcaggccc gcggcctctt cgcgcccatc
    20641 agcccggcgg ataccgaacg cgtcgacgtt ctcctccacc accttgactc cacccggccc
    20701 cccgagcgct gccccctccg cgagaagcac gagtcgtgac tgccccgtgt cgtcacgcaa
    20761 ccgaaccccg ctcccgcatc aggccgacac cttcgatgtc ccgcccgcgc ggaccagcgt
    20821 ccgcccctgt cctgatctcc gagaggagct gcgatgcacc accatgttgg ccgcctgatc
    20881 gccaaccgct accggatcac cgaaccggcc tcaccgggcg acgatgcagc cggtttcctc
    20941 gccaccgacg agcggcaggc caccgaagtc accgtgctcg tccgccccta cgccctgccc
    21001 gaggtactca tacccgacga ctcccaccgg tacgggcccc gcaccgatcg ggcaccgtgg
    21061 gaagcggcga agatcaccga catcgtgcgg gtggtcaccc aactgcccga gcacaagcac
    21121 gtcggcgtac ttcgcgatgc cgccgccgac ggcgacctcg tgtggctcgt ccaggagcgc
    21181 atcgccccgg gcgaaccgct atcccgaaca ctgacccgcg gtccggccga cccgcatcgc
    21241 gctgcggaga tcgcgcacga ccttctgcgg ggcctacggc acctgcaccg gcgcggctgg
    21301 caccacggca acatcacgcc gcagaccgtc tggctcgacg actacggcaa cgccattctc
    21361 accggcctgg atcaggccgt tctcgacgac ctggtctgcg ggattccccg cagcatgcct
    21421 caaccgcccg ccccgccacc cgcagtcacc ggacccggct tccgcacgcc accgcagccc
    21481 gccgccaccg cacccccggt cgccgtacgg ccgggagcaa tcggcgggat cgcgggcggc
    21541 gtacgcgccg acgccttccg cggcaccggc gccggaccac gggcggccgt tgcccggccc
    21601 cggccgcaca ccgaagccgc accccccgaa ccggccacgc ccgcggctcg cccgccgctc
    21661 accccgctgg aggccggccg cgcgcagcag ctccgcatga tcacggtggg atacgtggtg
    21721 gagcggtggg cgcccgagca ggcgctcctc ctcagcgacg caacgcccgt cataccgccg
    21781 gtcggcccgt caaccgacct ctgggcactg ggcgccctgc tgttcagggc cgtgacggga
    21841 ggcccgccat accctgaact ccatgacaca gccgagctgc tggacatggt ccgctccgag
    21901 ccgcccgcct acgcggagga caccggtgcc ctgcggccac tgatcgaaca gctcctctgc
    21961 tccgaccccc tcaagcgccc gagtaccgag gagctgctgc gctggatcgc ctccatagcg
    22021 cgtgacgccc cagagcccac cacggtcgcc cccgcccggg aacccgctcc gccccctggg
    22081 accagcctgg ttctgcgctt ccgcgggcac ctcgtacgac ggagcagaaa agccatgccc
    22141 ccgtcacggc ctgttcgccg ccgggcccgt catcgacggc ccgactcacg tctacggatc
    22201 ccgccacgaa ccgtctgcct catcacgctc accgcggcca cggccctcac cttcagcgtc
    22261 tacaccagca cccgggcccc tggccccaac cacgcacccg ccgacgaccg gcatctcccg
    22321 ccgcaaccct cggcccccgg accgtcgcct gatacccagc cggtcgtccg tgacccggcc
    22381 ggcttcagca tcgccaccgc ccccggcgcc caccggcacg ccacaccacg cacagtcgag
    22441 taccggcaca acgggatcac catcactgtc gtgccggggc acgacacctt gcaccccagc
    22501 gaatcgccgc tcgactacca gagacggcag ccggaactcg ccgccgtccg agccgacccc
    22561 gaaagcacag cctccggact gcgcctcacc acgatcggcc aaggcggcac catcgccgaa
    22621 ggcacctacc ggttctctcc cgacgtcggt ccgccgacct acctacgcaa ccgggtcaat
    22681 gtcctcggcg gcaaactcca cgtcctcctg gtctccggac ctgtcgctcg ccacgagcag
    22741 atcgacgccg catacctcca ggcagccgag tcctatgagc ccacactcct agaacaacag
    22801 cccgcgcggc gcgcggcccc ctcctagtcc gcagaaactc gcacccggga ataaacagcg
    22861 ccgccggaga gccaaccctg gcggcgcaat tcgctattcc tgaatatgga aactcgacac
    22921 cgagaagggc aattgacaca gttccgccga ttcgattgac gagcccattt gcagacccct
    22981 aacgttgccc ggagtgtgcg aacaaggggc tacgtaaaag gcagttggca ggagcagcca
    23041 aggcgcggac catcaccccc gagggagtca cgaagctctc ccgccgggga tggtccgcct
    23101 cgatcggctg atcgtccccc cgcgccacaa cctgttcctg c
//
