LOCUS       NZ_CP117709            22214 bp    DNA     linear   CON 25-MAR-2024
DEFINITION  Streptomyces sp. MMBL 11-1 chromosome, complete genome.
ACCESSION   NZ_CP117709
VERSION     NZ_CP117709.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. MMBL 11-1
  ORGANISM  Streptomyces sp. MMBL 11-1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8003288)
  AUTHORS   Choi,S.S., Park,H.S. and Lee,H.K.
  TITLE     Whole genome sequence of Streptomyces sp. MMBL 11-1 from novel
            marine Actinomycets
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8003288)
  AUTHORS   Kim,E.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-FEB-2023) MMBL, Inha university, 105, Building C, 100
            Inha-ro, Incheon, Michuhol-gu 22212, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 03-SEP-2021
            Assembly Method                   :: BLASTN v. 2.7.1+
            Assembly Name                     :: De novo
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 99.91x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028622875.1-RS_2024_03_25
            Annotation Date                   :: 03/25/2024 07:47:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,554
            CDSs (total)                      :: 7,455
            Genes (coding)                    :: 7,322
            CDSs (with protein)               :: 7,322
            Genes (RNA)                       :: 99
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 78
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 57 of 134
            Pseudo Genes (incomplete)         :: 101 of 134
            Pseudo Genes (internal stop)      :: 16 of 134
            Pseudo Genes (multiple problems)  :: 36 of 134
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:00:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 69577
            Orig. end                         :: 91791
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP117709.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from professor Eung-Soo Kim
            (In-ha university).
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22214
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22214
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22214
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12214](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12214
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    22..37
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.85"
                     /tool="antismash"
     gene            complement(142..846)
                     /locus_tag="PSQ21_RS00340"
     CDS             complement(142..846)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382269.1"
                     /locus_tag="PSQ21_RS00340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4230 domain-containing protein"
                     /protein_id="WP_274028283.1"
                     /transl_table=11
                     /translation="MTSSDVTTESAPHGDRKSDARPSRWWPKALGAAVAALALLFVGSG
                     LSLLPGLDDLFGEETHDRSGPAVLKSIQDMSAYEAASGNFQVVVDLEKDAKFVPDALRG
                     TRTLFVGAGTVGASVDLGKVTEGGVVVNEDRTAAELRLPHAVLGRPALDPDRSYAVSKQ
                     RGLLDRLGDLFSDNPGSEQAVNKLAAQHISEAAKESELTARAEKNTADMLKGLLGSLGF
                     ERVTVRYGDDQG"
     misc_feature    837..851
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.56"
                     /tool="antismash"
     gene            complement(1104..1895)
                     /locus_tag="PSQ21_RS00345"
     CDS             complement(1104..1895)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971173.1"
                     /locus_tag="PSQ21_RS00345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4389 domain-containing protein"
                     /protein_id="WP_274028285.1"
                     /transl_table=11
                     /translation="MAEGQWSPGRKETDADEFRPVLDIVEPARQRRLTVFLRLLLLIPH
                     FIVLLVLHIAAFFTVVVGWFAALALGRLPDPVFRFLTGVLGYDMRVSASDMLLIDRYPP
                     FALTPPADYPAQIEVRPTPLNRLAVLFRVFLMIPAAIVQSLAVYGWWALAFVWWLITLC
                     LGRMPRPLFEATAATLRYRMRFSAYAMMLTPAYPKGLFGDDDPAVAPGGRSRSATRPLV
                     LSSAAKWLVVLFLVLGLAGHITSSVTASTADDTSDTRLVGS"
     gene            complement(2007..2639)
                     /locus_tag="PSQ21_RS00350"
     CDS             complement(2007..2639)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382265.1"
                     /locus_tag="PSQ21_RS00350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VanZ family protein"
                     /protein_id="WP_274028286.1"
                     /transl_table=11
                     /translation="MTAEANPRTRQGTWVRVLVRGAILTVVLLGLVAFSVLLARVTLTP
                     SPASEDLVTANLRPGRSLRQYAEDYTFLAACKQAGGNLLLGVPFGLLLPFFGPRRLRMI
                     RTTLLTALAMATVELIQGALVEGRAFDIDDVILNTAGALLGYFVLGRRISRRYYTYADD
                     AGSPAPAAEKREDGPERVPRTAARTRAGDAARTETAPTKLRDRLRGR"
     gene            2739..3239
                     /locus_tag="PSQ21_RS00355"
     CDS             2739..3239
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971171.1"
                     /locus_tag="PSQ21_RS00355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_274028288.1"
                     /transl_table=11
                     /translation="MSAREKKDLLDEADRLRTEGRPGEARDLLLALTAEYPDDAEVVCR
                     TAWIHDALGLESEAVPYYERALAHPALAAEDRRGALLGLGSTYRILGRYGQAVETLRRG
                     VEEFPDDGSLRTFLAMALYNVDEHQESMRLLLELTAATSRDPYVQEYRRAIEHYAKDLD
                     ETV"
     gene            complement(3546..3806)
                     /locus_tag="PSQ21_RS00360"
     CDS             complement(3546..3806)
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956431.1"
                     /locus_tag="PSQ21_RS00360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="WP_274028290.1"
                     /transl_table=11
                     /translation="MKSRIHPVSRPVVFRDRAADVAFLTRSTADSGERVAWEDGNTYPV
                     IDVETSSASHPFYTGGSQVHDTAGRVERFRRRYGPGETSAS"
     misc_feature    4032..4047
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.81"
                     /tool="antismash"
     gene            4261..5688
                     /locus_tag="PSQ21_RS00365"
     CDS             4261..5688
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956434.1"
                     /locus_tag="PSQ21_RS00365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_274028293.1"
                     /transl_table=11
                     /translation="MPSPLFADHPAPQPPAHDAVDALIHRTRRLRGDVDAVRRDAVVFD
                     EDDPQLRWQRALCELAVQHLDNLDEHLGQLRAGLPDRSADDAPRAVEVPDDPRAGSPLS
                     RVGSAEWNLLTDESRWSEELYEIFGRPPGSTPLSLDDLPSVLLAEDQPLLTAMVTGCLV
                     DGRPMDGEFRIVRPDGRLRTLHMTGEPVLDGEGSTASMWAVLRDVSELRRGEQAVSANR
                     ASVRRAEHIERTEHRMAVELQEAVLPPWRGSLRLPTRGPGALDIAAHYLPSQASGLIGG
                     DWYDAMELPDGRTLLTVGDLTGHGIPATSAMAMMLGALRGMAVAGIEPGALMGHLNQVL
                     ETSMQPALGSALCCRFDPDTSVLSWAQAGHPAPLLFRHGSGRLLPPPDGMLLGAASNVA
                     FEQDEVRLYPGDVLVLHTDGLIRRGNRGAGPEALLALAPRFAEARTAQECVRSVVEEFG
                     GTDRLDDACVLVARIGA"
     gene            complement(5740..7227)
                     /locus_tag="PSQ21_RS00370"
     CDS             complement(5740..7227)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458453.1"
                     /locus_tag="PSQ21_RS00370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_274028295.1"
                     /transl_table=11
                     /translation="MSGEPNTRLSDLFGLAGWSKGELARMVNRQAAAMGHPQLATDTSR
                     VRRWIDMGESPRDPVPEVLAALFTERLGRVVTIEDLGFGRRGRVGKRRDSGTEHHPDAL
                     PWAPERTAAVLTEFTGMDLMLNRRGLVGAGAALAAGSTIAGPMYDWLHSDPAPAADAPR
                     ANDPLHADPAGFDRYEAAPVGSEEIEALEHSVTVFRAWDASRGGGLQRKAVVGQLNEVG
                     GMLAYRHPDHLQRRLWGVAANLAVLAGWMSHDVGLEPTAQKYFVIAAHAAREGGDRPRA
                     GEALSRAARQMVHLGRPDDALDLMKLAKSGSGDETLPRTQAMLRTIEAWAQASMGHGQA
                     MRRTLGEAEELFVSDKSDVPPPSWMQMFDEADMHGMQALAFRTLAEHDQGAAVIAQRHA
                     KQALELRDTERQRSKIFDYISLASACFIANDPEQADRYARLALVSMGETSSHRTWDRLR
                     EMYRLTGQFAGHAGIQDLREQIELSMPPSQKAKGMRI"
     gene            7459..8595
                     /locus_tag="PSQ21_RS00375"
     CDS             7459..8595
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060711.1"
                     /locus_tag="PSQ21_RS00375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_274028296.1"
                     /sec_met_domain="APH (E-value: 8.7e-17, bitscore: 60.5,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTASSSVSAPPRPLRPMGAGGGPYLAPHAGAPVQGPGRARRAPG
                     PGAGPLSGRIDLSGPQGAQVRMAIASVQRICPEFNPVQVLRRSGRSVLIVGTTGRATAV
                     AKCLLDHSPAWTERFRHEIAAYRAFVRHRPPVRAPRLIAADPENCTLVIERMPGRVAAL
                     TRHPAEAPPRADIRAALGAIARVNAWRPPPGLFEAPLDYASRIARYHELGLFTDRDLGD
                     LQKLLHGLAHAGGRQGMGQFCHGDALLSNILLSPTGPVLVDWEHAGWYLPGYDLATLWT
                     VLGDAPVARRQISQLAQARGPAARDAFLVNLMLVLTREIRNYETAVQRAMREAPAAGAG
                     ADRPGALSSGEEQRLLLRRLHDDCAMARRAVRAAVGTR"
     misc_feature    7780..7782
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            9163..9837
                     /locus_tag="PSQ21_RS00380"
     CDS             9163..9837
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971163.1"
                     /locus_tag="PSQ21_RS00380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="WP_274028297.1"
                     /transl_table=11
                     /translation="MPRISTLRITRSHKIATAVLVAAGSVTAIAATGAPSEAQATATRP
                     SVSVEPVAAAGIPTAKDAAAKKAAQETAAKEAAAKKALAARKATAEKDAEEARSEKQAA
                     NRSTERKAPAPKKFANNLDGWIRESLDIMKKKNIPGSYEGLHRNIMRESSGNPNAVNDW
                     DINARNGIPSKGLLQVIQPTFDAYHVKGTPKNLTDPVANITAAANYAADRYGSIDNVDS
                     AY"
     misc_feature    complement(9885..9899)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.2"
                     /tool="antismash"
     gene            10001..12214
                     /locus_tag="PSQ21_RS00385"
     CDS             10001..12214
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956438.1"
                     /locus_tag="PSQ21_RS00385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="germacradienol/geosmin synthase"
                     /protein_id="WP_274028299.1"
                     /sec_met_domain="T1TS (E-value: 1e-83, bitscore: 280.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQPFSLPDFYVPYPARLNPHVEAARTHTRAWARSMGMLEGSGIW
                     EEKDLEAHDYALLCAYTHPDCSAEALSLVTDWYVWVFFFDDHFLELFKRTPDREGGKRY
                     LDRLPSFMPMERGAPTPTPSNPVEAGLADLWARTVPSMSDAWRARFAEATENLLNESLW
                     ELANIHEGRIANPVEYIEMRRKVGGAPWSAGLVEYAAAAEVPASVADARPLRVLRDAFS
                     DGVHLRNDLFSYQREVEDEGENSNGVLVMEKFLGCSTQEAADAVNDLLTSRLQQFENTA
                     LTELGPLCAEKGLDPAQTAAVLAYVKGLQDWQSGGHEWHMRSSRYMNGGGAGEAVAGFG
                     MSAASIRFTLRSETARARSQSHVPYQHVGPSLLPDFDLPFGTTLSPHLEGARVRLVDWA
                     RRMGILEAQPGVPGSHIWDEERLIAIDLPLCAAGLDPDATPDELDLSSGWLAWGTYGDD
                     WFPVVHGRTRDLAGARLANERLSLFMPLDGEGTPEPVNALERSLGDLWRRTAGPMDPGG
                     RRTFRTAIESMTASWLWELANQAQNRIPDPVDYVEMRRATFGSDLTMSLCRLGHGRKVP
                     DEVYRSGPMRSLENAAADYACLMNDLFSYQKEIEYEGEVHNGVLVVQNFFGVDYPTGVA
                     IVHDLMNSRLRQFLHVAEVELPVLYDDFALDAEAREILAGYVRELEHWIAGILIWHRGC
                     RRYREEDLRRGHGTPWHISGPTGLGTSAAQVTRLMAQLAGSPA"
     gene            complement(12283..12840)
                     /locus_tag="PSQ21_RS00390"
     CDS             complement(12283..12840)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956439.1"
                     /locus_tag="PSQ21_RS00390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_274028300.1"
                     /transl_table=11
                     /translation="MHAPQTDGRLRKGERRKEELIEATLQVVAREGVAGVSHRAVAREA
                     GLPATAAAYHFTSIDDLLVAALTRCMEQDAHRMLRLADEADGGPEGITALAELLAKVVE
                     GPGRLLAEYELYLLAARRPELRGPTRHWLEAIAAYGRRYTDDPVRVRALKGVIDGLLLQ
                     GLLTDTPPTAAEFEAVLRHVLL"
     gene            complement(12898..14157)
                     /locus_tag="PSQ21_RS00395"
     CDS             complement(12898..14157)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458464.1"
                     /locus_tag="PSQ21_RS00395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_274028302.1"
                     /transl_table=11
                     /translation="MANPYGVLFRTPGSRAFTAAGFVARMPLSMAGIGIIAMVSQMRGD
                     YGLAGAVSATFTLSMALCGPRISRAVDRRGQSRVLPPVAGLSVMALGALLLCARYEAPD
                     WTLFGCAAVAGAMPNMAAMVRARWTHALKGSDRLHSAYSLESVVDELTFVVGPALSVAL
                     CTALFPEAGPLVAGVLLVLGVLMFVPQKRTEPPVVRPADGDPRGGSAIRGGALRLLALT
                     LVAGGAIVGTIDVVSVSFAEQQGSPAGAGVVLSVYAAGSAVAGLVFGALRLTTPLPRLL
                     VLGTAGTALTTLPLLLVGDLVTLTAAVFLPGLFFAPTMIVVMGLVERTVPPAALTEGMT
                     WAITGLSVGVASGAAVSGAIVDRFGPGGGFVVAVAAGAAALLTALCARRPLERSLRKRA
                     DRDAEEPAEGQTEAPGRSAH"
     misc_feature    14235..14248
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.02"
                     /tool="antismash"
     misc_feature    14244..14260
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.52"
                     /tool="antismash"
     misc_feature    14248..14257
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.86"
                     /tool="antismash"
     misc_feature    14250..14263
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.46"
                     /tool="antismash"
     gene            complement(14375..14875)
                     /locus_tag="PSQ21_RS00400"
     CDS             complement(14375..14875)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550733.1"
                     /locus_tag="PSQ21_RS00400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_003971159.1"
                     /transl_table=11
                     /translation="MSFLRRRSAATPAGPDFDVLAMDPGDWPGNLGAGLLPAPDGSCQG
                     VFLRYDLYGGRGPAMIIGNLPEGSPARETEEGQVPFEVAQLLLALENDEPIEVVSSEDV
                     PVMQGDNLLIVRRVKLSESRIACVQFDRSDGVLVTIASWDRPITDDLYTLLKPLPAELF
                     QQG"
     misc_feature    14878..14888
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.79"
                     /tool="antismash"
     gene            complement(15376..16374)
                     /locus_tag="PSQ21_RS00405"
     CDS             complement(15376..16374)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1015: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971138.1"
                     /locus_tag="PSQ21_RS00405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_274028305.1"
                     /transl_table=11
                     /translation="MLTEAVFRTDALQRSDRFAGWQQCVNNVIAPMEITSPYADDFWAD
                     HRLLRVEDTLLWPVRLQASRYRRTPRLIRQSDPGLLHMTLVRPGSGALYVEQGGLRSTA
                     ETHDLYVLDMSRPCDVRTADEPIVGVGVDLPRSLLPLPASVPLDDVLGRRLSGRHGFGA
                     LLTQFVTHLVDPADVYGPADAARLHRVLLDLAAGLLAGGLDREAALSPEARTRNLVLTI
                     RSFIGRNFHDPKLTPAAVAAAHHISTRHLHRLFQQEGTTVAALIRSRRLERARRDLADP
                     HLLDTPVQTIAARCGFGVPAHFSRVFRADQGMSPSDYRHTRLRGRTEPVVR"
     gene            16636..17931
                     /gene="paaK"
                     /locus_tag="PSQ21_RS00410"
     CDS             16636..17931
                     /EC_number="6.2.1.30"
                     /GO_function="GO:0047475 - phenylacetate-CoA ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (82-332). E-value: 2.4e-23.
                     Score: 74.3. Matches aSDomain:
                     nrpspksdomains_PSQ21_RS00410_AMP-binding.1"
                     /codon_start=1
                     /gene="paaK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458485.1"
                     /locus_tag="PSQ21_RS00410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phenylacetate--CoA ligase PaaK"
                     /protein_id="WP_274028306.1"
                     /sec_met_domain="AMP-binding (E-value: 5.1e-26, bitscore:
                     89.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAMLDATERLGRGELEALQLERLRSTLRHAYDAVPFYRSAFDSA
                     GLRPDDCRTLADLARFPFTVKADLRDNYPFGMFAVPEHEVRRIHASSGTTGRPTVVGYT
                     ERDLDTWADVVARSIRAAGGRPGHKVHVAYGYGLFTGGLGAHYGAERLGCTVIPASGGM
                     TARQVRLIQDFRPEIIMITPSYMLTLLDEFERQGVDPRSTSLKVGIFGAEPWTEGMRRE
                     IEDRFAIDAVDIYGLSEVMGPGVAQECVETKDGLHIWEDHFYPEVVDPLTGEVLPDGEE
                     GELVFTSLTKEAMPVIRYRTRDLTRLLPGTARTFRRMEKVTGRSDDMVILRGVNLFPTQ
                     IEEIVLRTPAVAPHFQLRLTRQGRLDALTVRAEARTDATAADREKAALAIAAAVKDGVG
                     VSVGVEIVDPESLERSVGKIRRIVDLRASGTE"
     misc_feature    complement(16658..16672)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.02"
                     /tool="antismash"
     aSDomain        16882..17631
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PSQ21_RS00410_AMP-binding.1"
                     /evalue="2.40E-23"
                     /label="PSQ21_RS00410_AMP-binding.1"
                     /locus_tag="PSQ21_RS00410"
                     /protein_end="332"
                     /protein_start="82"
                     /score="74.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="HEVRRIHASSGTTGRPTVVGYTERDLDTWADVVARSIRAAGGRPG
                     HKVHVAYGYGLFTGGLGAHYGAERLGCTVIPASGGMTARQVRLIQDFRPEIIMITPSYM
                     LTLLDEFERQGVDPRSTSLKVGIFGAEPWTEGMRREIEDRFAIDAVDIYGLSEVMGPGV
                     AQECVETKDGLHIWEDHFYPEVVDPLTGEVLPDGEEGELVFTSLTKEAMPVIRYRTRDL
                     TRLLPGTARTFRRMEKVTGRSDDMVILR"
     CDS_motif       17599..17661
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PSQ21_RS00410_0001"
                     /evalue="4.60E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="PSQ21_RS00410"
                     /protein_end="342"
                     /protein_start="321"
                     /score="13.0"
                     /tool="antismash"
                     /translation="TGRSDDMVILRGVNLFPTQIE"
     gene            complement(18106..19605)
                     /locus_tag="PSQ21_RS00415"
     CDS             complement(18106..19605)
                     /NRPS_PKS="Domain: AMP-binding (13-406). E-value: 3.3e-94.
                     Score: 307.7. Matches aSDomain:
                     nrpspksdomains_PSQ21_RS00415_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606702.1"
                     /locus_tag="PSQ21_RS00415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA synthetase"
                     /protein_id="WP_274028307.1"
                     /sec_met_domain="AMP-binding (E-value: 3.7e-97, bitscore:
                     324.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGVRSSTVDGVLTRSARRTPGATAVRYAGRAWTYRSLDAAVSTA
                     AAVLTEEHALAPGDRVAAYAHNSDAYLIGFLACARAGLVHVPVNQNLTGDDLAYLLDQS
                     GSSLVLTDPDLAGRLPAGPPVRALRDAPGSLLDALETERAFTPRRPPASDDLVQLLYTS
                     GTTALPKGAMMTHGALVHEYVSAITALGLAANDRPVHSLPLYHSAQMHVFLLPYLAVGA
                     ENTILDAPDAATVFDLVEAGLADSLFAPPTVWIGLANHPEFATRDLAGLRKAFYGASVM
                     PVPVLERLREHLPHLAFFNCFGQSEIGPLATVLGPDEHEGRMESCGRPVLFVEARVVDE
                     KGEEVADGTPGEVVYRSPQLCSGYWDKPEETAEAFRDGWFHSGDLAVRDAEGYLTVVDR
                     VKDVINSGGVLVASRQVEDALYTHPAVAETAVIGLPDDRWIEAVTAVVVLRGEAGESEL
                     IAHAREKLTAFKAPKRVVFVESLPRNASGKILKRQLRDELA"
     aSDomain        complement(18388..19566)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PSQ21_RS00415_AMP-binding.1"
                     /evalue="3.30E-94"
                     /label="PSQ21_RS00415_AMP-binding.1"
                     /locus_tag="PSQ21_RS00415"
                     /protein_end="406"
                     /protein_start="13"
                     /score="307.7"
                     /specificity="substrate consensus: Leu"
                     /tool="antismash"
                     /translation="TRSARRTPGATAVRYAGRAWTYRSLDAAVSTAAAVLTEEHALAPG
                     DRVAAYAHNSDAYLIGFLACARAGLVHVPVNQNLTGDDLAYLLDQSGSSLVLTDPDLAG
                     RLPAGPPVRALRDAPGSLLDALETERAFTPRRPPASDDLVQLLYTSGTTALPKGAMMTH
                     GALVHEYVSAITALGLAANDRPVHSLPLYHSAQMHVFLLPYLAVGAENTILDAPDAATV
                     FDLVEAGLADSLFAPPTVWIGLANHPEFATRDLAGLRKAFYGASVMPVPVLERLREHLP
                     HLAFFNCFGQSEIGPLATVLGPDEHEGRMESCGRPVLFVEARVVDEKGEEVADGTPGEV
                     VYRSPQLCSGYWDKPEETAEAFRDGWFHSGDLAVRDAEGYLTVVDRVKDVINS"
     CDS_motif       complement(18481..18567)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PSQ21_RS00415_0002"
                     /evalue="1.10E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="PSQ21_RS00415"
                     /protein_end="375"
                     /protein_start="346"
                     /score="24.1"
                     /tool="antismash"
                     /translation="DGTPGEVVYRSPQLCSGYWDKPEETAEAF"
     CDS_motif       complement(19078..19131)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PSQ21_RS00415_0001"
                     /evalue="2.70E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="PSQ21_RS00415"
                     /protein_end="176"
                     /protein_start="158"
                     /score="20.0"
                     /tool="antismash"
                     /translation="LLYTSGTTALPKGAMMTH"
     gene            19759..22173
                     /locus_tag="PSQ21_RS00420"
     CDS             19759..22173
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019761833.1"
                     /locus_tag="PSQ21_RS00420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acylase"
                     /protein_id="WP_274028308.1"
                     /transl_table=11
                     /translation="MTLRKRLRLFGVAGLALFTVTASLPPAAASGAQPSRHPSGGGLSA
                     VIRYTEYGIPHIVAKDYAELGFGTGWAQAADQVCTLADGFLTVRGERSRFFGPDAATDH
                     SLSSAATNLSSDLYFRGVRDSGTVEKLLKEPAPAGPSRDVKETMRGFAAGYNAWIAQNR
                     ITDPACRGASWVRPVTALDVAARGYALAVLGGQGRGIDGITAARPPTAAPPAAGVTPEE
                     AATAAERLLSTQNADMGSNAVAFDGSTTVNGRGLLLGNPHYPWQGGRRFWQAQQTIPGE
                     LNVSGASLLGSTTISIGHNADVAWSHTVATGVTLNLHQLTLDPADPTAYLVDGKRERMT
                     RRTVSVPVKGAADVTRTQWWTRYGPVVTSMGPTLPLPWTASTAYALNDPNATNMRMADT
                     GLGFGKARSTGDVERALHRSQGMPWVNTIAADRAGHSFFAQSQVLPRITDELAERCSTP
                     LGRATYPASGLAVLDGSRADCALGSDPDAVRPGIFGPGRMPVLKNQPYVENSNDSAWLT
                     NAERPLTGYERVFGTIATPRSLRTRGAVEDVASMADRGRLRVADLQRQQLANRAPAGDL
                     AASEAAKWCAALPGGTAVGSDGTRVDVSAACRVLRRWDRSVDSDSRGALLFDRFWRKAS
                     AAPAAELWRTPFDPADPVRTPRDLNTAAPVLGRALADAVAELRAAGIALDAPLGEHQFV
                     VRNGKRLPIGGGTESLGVWNKTEPRWDAAGGGYTEVSSGSSYIQAVGWDDSRCPVARTL
                     LTYSQSENPKSPHYSDQTRLYAGERWVTSRFCERDIARSPDLRVVRVRERR"
     misc_feature    19765..19767
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 ggtgtccgaa aaggccttgc acttggacta gaccataccg atggacgcgt tcacgtcaag
       61 agcggtacgc ggcgggaggc ctgcccgtcc gacgcgcacg gacggccccg cgcatccggc
      121 gcgtccaccc gggtgacgcg atcacccctg gtcgtccccg tagcggaccg tgacgcgctc
      181 gaagccgagg gagccgagga gacccttcag catgtcggcg gtgttcttct ccgcccgagc
      241 ggtcagttcg ctctccttcg ccgcttcgga gatgtgctgg gcggcgagct tgttgaccgc
      301 ctgctcactg ccggggttgt cggagaacag atcgcccagc cggtcgagga gaccgcgctg
      361 tttggacacc gcgtaggaac ggtcgggatc gagggccggc ctgcccagca ccgcgtgcgg
      421 cagccgcagt tcggcggcgg tgcggtcctc gttcaccacg acgccgccct cggtgacctt
      481 gcccaggtcg acggaggcac cgaccgtgcc cgccccgacg aacagggtgc gggtgccgcg
      541 cagggcgtcg gggacgaact tcgcgtcctt ctccagatcg acgacgacct ggaagttgcc
      601 cgaggcggcc tcgtacgcgc tcatgtcctg gatcgacttg agcaccgcgg ggcccgaacg
      661 gtcgtgggtc tcctcgccga agaggtcgtc gagtcccggc agcaggctga gcccgctgcc
      721 gacgaacagc agggccagtg cggccacggc cgcgccgagg gccttcggcc accaccggga
      781 ggggcgggcg tcgctttttc ggtcgccgtg cggcgcggac tctgtggtta cgtcgctgga
      841 cgtcatgttc tgcgtgtggc ccgcgccggg tgctttcagt ccaccacccc ctcatcctga
      901 acgaactccc gcacaaaatg ggcctgttcc ggtacgaccg ggcagacgcg agggcgcttc
      961 cccggttgcc gggtccgctc ggagcagcgc ggccgccacc cgcacgcgat cgctctcccc
     1021 cgtcggagag gaccaccgga tcgaagcccg ctcagccggg accaggtctc cctcgttggc
     1081 aggggacagc cacgagcccc gcttcaggaa ccgacgagac gcgtgtcgga ggtgtcatcg
     1141 gccgtcgagg cggtcacgga cgaggtgatg tgccccgcca ggcccagcac gaggaacagc
     1201 accacgagcc atttcgcggc gctgctcagg accagcgggc gggtggcgga gcgcgaccgc
     1261 ccgcccgggg ccacggccgg gtcgtcgtcg ccgaacaggc ccttggggta ggcgggggtg
     1321 agcatcatgg cgtacgcgga gaaccgcatc cggtagcgca gcgtggccgc cgtcgcctcg
     1381 aacagcggcc ggggcatccg gccgagacac agcgtgatca gccaccagac gaaggccagc
     1441 gcccaccacc cgtacacggc gaggctctgc acgatcgccg ccgggatcat caggaagaca
     1501 cggaacagca ccgcgaggcg gttgagcggg gtgggccgca cctcgatctg cgccggatag
     1561 tccgccggcg gggtcagggc gaagggaggg tagcggtcga tgagcagcat gtcgctcgcc
     1621 gagacgcgca tgtcgtagcc gaggacgccg gtcaggaagc ggaagacggg gtcgggcagc
     1681 cgtcccagcg ccagggccgc gaaccagccc acgacgacgg tgaagaacgc cgcgatgtgc
     1741 aggacgagca gcacgatgaa gtgcgggatg agcagcagca gccgcaggaa gacggtcagc
     1801 cgccgctggc gtgccggttc cacgatgtcc aggacgggcc ggaactcgtc cgcgtccgtc
     1861 tccttgcggc ccgggctcca ctggccttcg gccatgtcgc tcctcctcgg caggggatcc
     1921 gtacggcatc cgcgcgcagg acgtgtcccc accgtgcgac cgctccgggc agcccgcaaa
     1981 cggcccggcc cgaacgggtg cccgggtcag cgcccgcgga ggcggtcgcg cagcttcgtg
     2041 ggggcggtct ccgtacgggc ggcgtcgccg gcccgggtgc gggcggccgt cctcggcacg
     2101 cgctcgggcc cgtcctcacg cttctccgcc gccggggcgg gcgaacccgc gtcgtcggcg
     2161 taggtgtagt agcggcggct gatccggcgg ccgagcacga agtaccccag cagtgcgccc
     2221 gccgtgttga ggatgacgtc gtcgatgtcg aaggcgcgcc cctcgaccag ggccccctgg
     2281 atcagctcga cggtggccat ggcgagggct gtcagcagcg tcgtccggat catgcgcagg
     2341 cggcgaggcc cgaagaacgg cagcaggagt ccgaacggca cgccgagcag caggttcccg
     2401 ccggcctgtt tgcaggcggc gaggaaggtg tagtcctcgg cgtactggcg cagcgagcgg
     2461 ccggggcgga gattcgcggt gacgaggtcc tcggaggccg gtgagggcgt gagcgtcacc
     2521 ctggccagca ggacggagaa ggccaccagc cccagcagca ccaccgtcag gatcgcgcca
     2581 cgcaccagca cacgtaccca tgtcccctgg cgtgtacggg gattcgcctc tgcggtcatg
     2641 gccgacgggt gcccccgccc gcccggaaca cacgcccgga ccgccccgtg gggcgaaggt
     2701 tcacccggcc gcccccgttc gcctgcgacg atgtgcgcat gagcgcacga gagaagaagg
     2761 acctgctgga cgaggccgac cggttgcgta cggaaggccg gcccggggag gcgcgcgacc
     2821 tgctcctcgc cctgaccgcc gagtatcccg acgacgcgga ggtggtctgc cggacggcgt
     2881 ggatccatga cgcgctgggg ctggagtcgg aggcggtgcc ctactacgag cgcgcactgg
     2941 cgcatccggc gctggccgcg gaggaccggc gcggggcgct cctggggctg ggcagtacgt
     3001 accggatcct cggccggtac gggcaggcgg tggagacgct gcgccggggc gtcgaggagt
     3061 tcccggacga cggctcgctc cggacgttcc tggccatggc cctgtacaac gtcgacgagc
     3121 accaggagtc gatgcgcctg ttgctggagt tgactgccgc gacaagccgg gacccgtacg
     3181 tccaggagta ccggcgggcg atcgagcact acgcgaagga cctcgacgag accgtgtgac
     3241 ccgggcgggc gccgaggcgg cccgctacga gcgggcaagg ggaagccccg gccggatcgg
     3301 gggaatccgg ccggggcggt ctgcgtgcgg gtgggaaggg cgatcgcctc tcggcggacg
     3361 gctccatggg cttcgggagt gcgttcattc cccctgggcc acaggaaagt cccggggcac
     3421 cgccccctcg ttcccgcata tagatgaacg ataaaccatc ctgggccgca cccggaaatc
     3481 cacccccgca catgtgaccc acggcacgga attccgggct tcccccctgg tcggggcccc
     3541 ttcggtcagc tcgcggacgt ctcaccgggg ccgtagcggc ggcggaaccg ttcgacgcga
     3601 cccgccgtgt cgtgcacctg gctgccgccg gtgtagaacg ggtggctcgc cgacgaggtc
     3661 tccacgtcga tcacggggta ggtattgccg tcctcccacg ccacgcgctc gcccgagtcg
     3721 gcggtggagc gggtcaggaa ggcgacatcg gccgcgcggt cacggaagac cacgggacgg
     3781 gacacggggt ggatgcggga cttcatcgat gcgttccttc ctcaccgcgg acagcggtga
     3841 cgtacggggg gggacgggcc ccttccggac ggtcagcggg cctcgcggac cagaacgcgc
     3901 cggccgtcgg cggagtcgga cgtgcggagc tccagccggt tcgcttgcgt tctggtgggg
     3961 taacgcgggc cgcccgcccg gcattccctg cccaccgccc cctcggaagc gtcgcggcca
     4021 actcgcccca gacgtacgcc tgttcggatc gtctccgcat ccgaaagccg ctggcatatg
     4081 ccagaagcaa ggacccgtcg agtgttgcca aagcccttac ggaccgccgc ggcctgtgcg
     4141 acagtcgtag cggtccaccc tccagaaccg ggtggagtct ttcgttcgca tcaggccgga
     4201 cccgggagcc gacatgatcg aaacgagagg ccctgggccg cgcctgtatc ggagtacgag
     4261 atgccgtccc ccctcttcgc ggaccacccc gcaccacagc ctcccgcgca tgacgccgtc
     4321 gacgccctga tccaccggac gcgccggctg cgcggggacg tggacgccgt gcggcgggac
     4381 gccgtcgtgt tcgacgagga cgacccccag ctgcgctggc agcgcgccct gtgcgagctt
     4441 gccgtgcagc acctggacaa cctcgacgaa cacctgggcc agctccgcgc gggcctgccg
     4501 gaccggagtg ccgacgacgc cccccgggcg gtggaggtcc ccgacgaccc gagggccggt
     4561 tctccgctca gccgggtggg cagcgccgag tggaacctcc tcaccgacga gtcccgctgg
     4621 tccgaggagc tgtacgagat cttcggcagg ccgcccggct ccacccctct ctccctggac
     4681 gacctgcctt ccgtgctgct cgccgaggac cagccgctgc tgaccgccat ggtgacgggc
     4741 tgcctcgtcg acggccggcc gatggacggc gagttccgca tcgtgcgccc cgacggccgt
     4801 ctgcgcacgc tgcacatgac gggcgagccc gtcctggacg gggagggcag caccgcctcc
     4861 atgtgggcgg tcctgcggga cgtcagcgag ctgcggcgcg gcgagcaggc cgtgagcgcg
     4921 aaccgcgcgt cggtgcggcg cgcggagcac atcgaacgga ccgaacaccg catggccgtg
     4981 gagctccagg aggccgtcct gcccccgtgg cgcggatctc tgcggctccc gacgcgggga
     5041 cccggcgccc tggacatcgc cgcgcactac ctcccttccc aggcgagcgg cctcatcggc
     5101 ggcgactggt acgacgcgat ggaactgccg gacgggcgca ccctcctcac cgtcggcgac
     5161 ctcaccgggc acggcatccc cgccacctcg gccatggcga tgatgctggg cgcgctgcgt
     5221 ggcatggccg tcgccggcat cgagccgggc gcgctgatgg ggcacctcaa ccaggtactc
     5281 gagacgtcga tgcagcccgc gctgggcagc gccctgtgct gccgcttcga ccccgacacc
     5341 tccgttctgt cctgggcgca ggccggacac cccgcgccgc tgctcttccg ccacggttcg
     5401 ggacggctcc tgcccccgcc ggacgggatg ctgctcggcg ccgcgtccaa cgtcgccttc
     5461 gagcaggacg aggtacggct gtaccccggt gacgtgctcg ttctgcacac cgacggcctg
     5521 atccgacgcg gcaaccgggg tgcgggcccg gaggcgctgc tcgccctcgc tcctcggttc
     5581 gcagaggccc gtacggcaca ggagtgcgtg cggagcgtcg tcgaggagtt cggcgggacc
     5641 gatcgcctgg acgacgcgtg cgtgctggtc gcccgaatcg gggcatgagg aagcgcggac
     5701 gtgtcggggc gtgagtgagc gcggagtggc gctgccgggt cagatccgca tgcccttggc
     5761 cttctggctc ggcggcatcg agagctcgat ctgctcgcgc agatcctgga tccccgcgtg
     5821 tccggcgaac tgaccggtga gccggtacat ttcgcggagc cggtcccagg tgcggtgcga
     5881 ggaggtctcc cccatcgaca ccagagcgag ccgtgcgtac cggtcggcct gttcggggtc
     5941 gttggcgatg aagcaggccg aggccagcga gatgtagtcg aagatcttcg accgctggcg
     6001 ttcggtgtcc ctcaactcca gcgcctgctt ggcatggcgc tgggcgatga ccgcggcccc
     6061 ctggtcgtgc tcggccagcg tacggaaggc gagcgcctgc atcccgtgca tatctgcctc
     6121 gtcgaacatc tgcatccaac tgggcggcgg cacgtcgctc ttgtccgaga cgaagagctc
     6181 ctcggcctcg ccgagggtgc gccgcatggc ctgcccgtgg cccatcgacg cctgtgccca
     6241 ggcctcgatg gtgcgcagca tcgcctgggt gcggggcagg gtctcgtcgc cggagccgga
     6301 cttggcgagc ttcatcaggt cgagcgcgtc gtcggggcgg cccaggtgca ccatctggcg
     6361 tgccgcccgg gagagcgcct ctccggcgcg cggccggtcg ccgccctcgc gggccgcgtg
     6421 ggccgcgatg acgaagtact tctgagcggt gggttcgagg ccgacgtcgt gggacatcca
     6481 gcccgccagg acggcgaggt tggcggcgac gccccacagg cggcgctgga gatggtcggg
     6541 gtggcggtag gcgagcatgc cgcccacctc gttgagctgg cccacgaccg ccttgcgctg
     6601 gagtccgccg ccccgggacg cgtcccaggc gcggaacacc gtgaccgaat gctccagggc
     6661 ctcgatctcc tcggagccga ccggtgccgc ctcgtaccgg tcgaaaccgg cgggatcggc
     6721 gtgcagggga tcgttggcgc gtggagcgtc ggccgccgga gcggggtcgc tgtgcagcca
     6781 gtcgtacatg gggccggcga tggtggagcc ggcggcgagc gcggcgcccg cacccaccaa
     6841 gccgcgtcgg ttgagcatga ggtccattcc cgtgaattcg gtgaggaccg ctgccgtccg
     6901 ttcgggcgcc cacggcagtg cgtcgggatg gtgttccgtc ccggagtcac gccgcttccc
     6961 cacacgcccg cgtcggccga acccgaggtc ctcgatggtc acgacacggc cgagccgctc
     7021 ggtgaacaga gccgccagca cttcgggcac gggatctcgg ggggattccc ccatgtcgat
     7081 ccagcgcctg acgcgcgagg tgtcggtggc cagctgcggg tggcccatgg ccgccgcctg
     7141 ccggttcacc attctcgcga gttcgccctt ggaccagccg gccaggccga acaggtcaga
     7201 aaggcgggtg ttgggttctc cggacacgtc aagcccccag gttctcggct gacttgacac
     7261 taaccccctg tcagatgcgc tgtgactatt cgccagggtt cgccagggtc cgccagatgg
     7321 tctgccaccc gcactccggt gtcaggtagg aaagcgccac cccgcccggc agccctaggt
     7381 actccccagg gtgccgaacg gccgtcggcc gggttggcgc acgtaccttg tcggcgcacg
     7441 aagggatctg tctcgcccat gtacacagca tcgtcctccg tgtccgcccc gccccgtccg
     7501 ctccgcccga tgggcgcggg cggcgggccc tatctcgctc ctcacgccgg cgcaccggtg
     7561 cagggtccgg gccgggcccg acgggccccg gggccgggcg ccggaccgct cagcggaagg
     7621 atcgacctgt ccgggcccca gggggcgcag gtgcggatgg ccatcgcctc cgtgcagcgc
     7681 atctgccccg agttcaaccc ggtccaggtg ctgcgccgca gcggccgttc ggtcctgatc
     7741 gtcggaacga ccgggcgggc caccgccgtc gcgaagtgtt tactggatca ctcaccggcg
     7801 tggaccgagc ggttccggca cgaaatagcg gcataccgcg cgttcgtccg gcaccgcccc
     7861 ccggttcggg cgccccggct gatcgcggcg gacccggaga actgcacgct ggtgatcgag
     7921 cggatgcccg gccgggtcgc cgctctcacc cggcacccgg cggaggcgcc gccgcgggcc
     7981 gacatccggg ccgcgctcgg agcgatcgcc cgggtgaacg cctggcggcc gccgcccgga
     8041 ctgttcgagg cgccgctcga ctacgcgtcg cggatcgcgc gctaccacga gctcggtctg
     8101 ttcaccgacc gtgacctcgg tgacctgcag aagctgctgc acggtctggc gcatgcgggc
     8161 ggcagacagg gcatggggca gttctgccac ggggacgccc tgctctcgaa catcctgctg
     8221 tcgccgaccg gtccggtgct cgtcgactgg gagcacgcgg gctggtatct cccggggtac
     8281 gacctggcga cgctgtggac ggtgctgggc gacgccccgg tggcacgacg tcagatcagc
     8341 cagctggccc aggccagggg gccggccgcg cgggacgcgt tcctggtgaa tctgatgctg
     8401 gtgctgaccc gtgagatccg caattacgag acggcggtcc agcgcgccat gcgcgaggcg
     8461 cccgcggcgg gggcgggggc cgaccggccc ggcgctctct cctcgggcga ggagcagcgg
     8521 ctgctgctgc ggaggctgca cgacgactgc gccatggcgc ggcgggccgt gcgggccgcg
     8581 gtcggcacac gctgagacgg gaggaggacg cgggcgaaca gcccgcccgc cgagaaacca
     8641 cagtgatgag accactgtga agaagaagcg cgctgcggga ccggtgccga cacaccgggc
     8701 ccgcagcgcg cttctgtgcg tcgcgaggcc tgcccaccgc ctcccggccg agccgacgcc
     8761 ggcccttccg tgccgaagtc gccgatgctc cgtacggcgg ccatgaggcc ccttccgagc
     8821 cgcgcctcct cgtgaccggg cgttgaccct gtgctgcccc ggggcccccg cgagtgaggc
     8881 ccgccacgag acccacatca cctacggcct ccggtagtag gcccgagccc tcccgtgcgg
     8941 cgtaacgaac cgcccaaatg gctcataaat tggcatctca cgatgaagag tagtaaaggc
     9001 ggtcattgct tcctatgtcg gtgcgcgcta accatggatt ccggcgagca ccgagtacga
     9061 gccgacgtcg atcacccatc ggcgatcgcg gcccggacgc ccggttcccg ccgacgcggc
     9121 gcgaaggccg cgaagcccgt cccccatagg aagagctcac gcatgccccg catctccacc
     9181 ctgcgcatca cccgctcgca caagatcgcc accgccgtgc tcgtcgcggc cggttccgtc
     9241 accgccatag ccgccaccgg cgccccgagc gaagcgcagg ccacggcgac ccggccctcc
     9301 gtctccgtgg agccggtcgc cgccgcgggc atccccacgg cgaaggacgc ggcggccaag
     9361 aaggccgccc aggagaccgc cgccaaggaa gccgcggcga agaaggccct ggccgcccgc
     9421 aaggcgaccg cggagaagga cgccgaagag gcgcgctccg agaagcaggc cgccaaccgc
     9481 tccaccgagc gcaaggcccc cgcgcccaag aagttcgcga acaacctcga cggctggatc
     9541 cgcgagtcgc tcgacatcat gaagaagaag aacatccccg gctcctacga ggggctgcac
     9601 cgcaacatca tgcgcgagtc cagcggcaac ccgaacgccg tcaacgactg ggacatcaac
     9661 gcgcgtaacg gcatcccctc caagggtctc ctccaggtga tccagcccac cttcgacgcg
     9721 taccacgtca agggcacccc gaagaacctc accgacccgg tcgccaacat caccgccgcc
     9781 gccaactacg ccgcggaccg gtacggttcg atcgacaacg tcgactccgc ctactgagcg
     9841 accgacttcc gaacgaccgg cttccgagca cgcaccaacg ccgcgattat gtgactaatc
     9901 gccgtcgtgc gtgctccgta tggccgaagg gtagtgctgc gcggacacca ccggtccgcg
     9961 cgtttccccg cgcggaggct tctggaaagg cctgacgcac atggcacagc ccttctcact
    10021 gccggacttc tatgttccgt atccggcgcg gctcaaccct catgtggagg cggcccgcac
    10081 gcacacccgg gcgtgggccc gctccatggg gatgctggag ggatccggca tctgggagga
    10141 gaaggacctg gaggcgcacg actacgccct tctgtgcgcc tacacgcacc ctgactgctc
    10201 ggccgaggcg ctctccctgg tcaccgactg gtacgtgtgg gtcttcttct tcgacgacca
    10261 cttcctggaa ctgttcaagc gcacgcccga ccgggagggc ggcaagcggt atctggaccg
    10321 cctgccctcc ttcatgccga tggagcgcgg cgccccgacg cccacgcctt cgaaccccgt
    10381 cgaggcgggg ctcgccgatc tgtgggcgcg cacggtccct tcgatgtcgg acgcctggcg
    10441 ggcccggttc gcggaggcga cggagaatct cctcaacgag tccctgtggg agctcgccaa
    10501 catccacgag ggccgcatcg cgaaccccgt cgagtacatc gagatgcgcc gcaaggtagg
    10561 cggcgcgccc tggtccgccg gtctggtgga gtacgcggcg gccgccgagg tgcccgcgtc
    10621 ggtcgccgac gcccgcccgc tgcgggtgct gcgggacgcg ttctccgacg gcgtgcatct
    10681 gcgcaacgac ctcttctcct accagcgtga ggtggaggac gagggggaga acagcaacgg
    10741 cgtgctggtg atggagaagt tcctcggctg ctccacgcag gaggccgccg acgcggtcaa
    10801 cgacctgctg acctcacggc tccagcagtt cgagaacacc gccctgaccg aactcggccc
    10861 gctctgcgcc gagaagggcc tcgacccggc gcagaccgcc gccgtgctgg cgtacgtcaa
    10921 ggggctccag gactggcagt ccggcggcca cgaatggcat atgcgctcca gtcgctacat
    10981 gaacggcggc ggcgcgggcg aggccgtcgc cggcttcggc atgtccgccg cctccatcag
    11041 gttcacgctc cgttcggaga ccgcgcgggc ccggagccag agccatgtgc cgtaccagca
    11101 cgtgggcccc tcgctgctgc cggacttcga cctgccgttc gggacgacgc tgagcccgca
    11161 tctggagggg gcccgggtcc ggctcgtcga ctgggcgcgg cggatgggca tcctggaggc
    11221 ccagccgggc gtaccgggtt cgcacatctg ggacgaggag cggctcatcg cgatcgacct
    11281 gccgctgtgt gcggcggggc tggatccgga cgcgaccccg gacgaactgg acctgtcctc
    11341 ggggtggctg gcctggggga cgtacgggga cgactggttc ccggtcgtgc acgggcggac
    11401 ccgggacctg gcgggggcgc ggctggccaa cgagcggctg tcgctgttca tgccgctgga
    11461 cggcgaggga acgccggagc cggtgaacgc cctggagcgg agtctgggcg acctgtggcg
    11521 caggacggcc ggtccgatgg atcctggcgg tcggcgcacc ttccggaccg cgatcgagtc
    11581 gatgaccgcg agctggctgt gggagctggc gaaccaggcg cagaaccgta tccccgaccc
    11641 ggtggactac gtggagatgc ggcgggccac gttcggttcg gacctgacga tgagcctgtg
    11701 ccggctcggg cacggcagga aggtcccgga cgaggtctac cgcagcggtc cgatgcgttc
    11761 cctggagaac gcggcggcgg actacgcgtg cctgatgaac gacctgttct cgtaccagaa
    11821 ggagatcgag tacgagggcg aggtgcacaa cggcgtcctg gtcgtgcaga acttcttcgg
    11881 cgtcgactat ccgacgggcg tggcgatcgt gcacgacctg atgaactcgc ggctgcggca
    11941 gttcctgcat gtcgccgagg tcgaactccc ggtgctgtac gacgacttcg ccctggacgc
    12001 cgaggcgcgg gagattctgg cgggctatgt gcgggagctg gagcactgga tcgcggggat
    12061 cttgatctgg caccggggct gccgccgcta ccgcgaggag gacctgcggc gcggtcacgg
    12121 cacgccctgg cacatcagcg gtcccacggg gctcggtacg tcggccgcgc aggtgaccag
    12181 gctgatggcc caactggcgg gcagcccggc gtagttcgtg aggtctcggc ccgccgtccg
    12241 gaggaacgca cggcgggccg ggaccgatgg cggaaccggc cgtcagagaa gtacgtgccg
    12301 gagcacggct tcgaactccg ccgccgtcgg cggggtgtcg gtcagcagcc cctggagcag
    12361 caggccgtcg atcacgccct tgagcgcccg cacccggacc gggtcgtcgg tgtagcggcg
    12421 gccgtacgcg gcgatggcct ccagccagtg ccgggtggga ccgcgcaact ccgggcggcg
    12481 ggccgcgagc aggtacaact cgtactccgc gagcagccgt ccggggccct cgacgacctt
    12541 cgccagcagc tccgccaacg cggtgatgcc ctcggggccg ccgtccgcct catcggccag
    12601 ccggagcatg cggtgcgcgt cctgctccat acagcgggtg agcgcggcga cgagcaggtc
    12661 gtcgatgctg gtgaagtggt aggcggcggc ggtggcgggc aggcccgcct cgcgcgcgac
    12721 cgcccggtga ctgacgccgg cgaccccttc ccgggcgacc acctgcagcg tggcctcgat
    12781 gagttcctcc ttccgtcgct cgcctttgcg caggcgtccg tcggtctgcg gtgcgtgcac
    12841 ggtgcctccg ggcttcgtgg cgggtgggga cggcgggcgc gcttcggctc cggcccgtca
    12901 gtgcgcggac cttccgggag cctcggtctg cccctcggcc ggctcctcgg cgtcgcggtc
    12961 cgcacgcttc cggaggcttc gctccagcgg acgccgggcg cacagcgccg tcagcagagc
    13021 ggccgcgccc gcggcgacgg cgacgacgaa gccaccgccg ggaccgaagc ggtcgacgat
    13081 cgctcccgac accgcggccc cggacgcgac acccacgctg aggccggtga tggcccaggt
    13141 catgccctcg gtgagtgcgg cgggtggcac cgtcctctcc accagcccca tcaccacgat
    13201 catggtaggc gcgaagaaga gccccgggag gaagacggcg gcggtcagcg tgacgaggtc
    13261 cccgacgagc agcagaggga gggtcgtgag cgccgtcccg gcggtgccga ggacgagcag
    13321 ccggggcagt ggcgtcgtga gcctgagtgc cccgaagacc agaccggcga cggcggaacc
    13381 ggccgcgtag accgagagga cgacaccggc gccggcgggc gagccctgct gctcggcgaa
    13441 ggagacgctc acgacatcga tggtgccgac gatggcgccg ccggccacca gggtgagggc
    13501 cagcaggcgg agtgctccgc cacggatcgc cgagccgcct cgcgggtcgc catcggccgg
    13561 ccggaccacc gggggttcgg tgcgcttctg ggggacgaac atgaggacgc cgagcaccag
    13621 cagcactccg gcgaccagcg gcccggcctc ggggaacagg gcggtacaca gggccaccga
    13681 gagcgcgggg cccacgacga aggtgagctc gtcgacgacc gattcgagcg agtaggcgct
    13741 gtgcagccgg tccgagccct tgagcgcgtg cgtccagcgg gcacgcacca tcgccgccat
    13801 gttgggcatc gcgccggcca ccgccgcgca gccgaacagg gtccagtcgg gggcctcgta
    13861 ccgggcgcag agcagcagcg cgccgagcgc catcacgctc agaccggcga cgggcggcag
    13921 cacccggctc tggccccggc ggtcgaccgc ccgggagatc cgcggaccgc agagggccat
    13981 ggacagggtg aaggtggcgg agacggctcc ggcgaggccg tagtcaccgc gcatctggga
    14041 caccatcgcg atgatgccga tgcccgccat ggacaggggc atgcgggcga cgaacccggc
    14101 ggcggtgaaa gccctcgatc cgggcgtcct gaacaggacg ccataggggt tggccatgcg
    14161 tggacctccg gaagggcgga cgtaggcggc cgttcgcggg gaacggccgc ccgaatcgag
    14221 cggtcgctac aatttgaacg ctcgtttcgt ttttttacca tagccctccc ccggtccgcc
    14281 tcccacccag ccctatgaag aatggcccgg ccccctcccc gggcaacgga aaaggccgcc
    14341 cggacggatc cggacggcct tgcgcaggga cgtttcagcc ctgctggaac agctctgcgg
    14401 gcagcggctt gaggagggtg tacaggtcgt cggtgatcgg ccggtcccag ctggcgatgg
    14461 tcacgaggac gccgtcgctg cggtcgaact ggacgcaggc gatacggctc tcggagagct
    14521 tgacgcggcg gacgatcagc aggttgtcgc cctgcatgac ggggacgtcc tcggagctga
    14581 cgacctcgat cggctcgtcg ttctccaggg cgaggagcag ttgggccacc tcgaagggga
    14641 cctggccctc ctcggtctcg cgggcgggcg agccttccgg aagattgccg atgatcatcg
    14701 ccgggccccg gccgccgtac aggtcgtaac ggaggaagac gccctgacag ctgccgtcgg
    14761 gggcggggag cagaccggcg ccgaggttgc cgggccagtc cccggggtcc atggccagga
    14821 cgtcgaagtc cgggcccgcg ggtgttgcgg cgctacggcg gcggaggaag gacatgctgc
    14881 catgttacgt gtcccggctc acgtcgcgga gccgggcccg ggccccgcgg gaccgggccc
    14941 gtcgcgctcg ctcagccggg cgggggctcc gctccggggg tccacacggc gaggaaccga
    15001 gcccctccgc cgtagggcga gttcggtgac gcccgcctcg gtgagcttcc agccctcgcc
    15061 ctcgtggcgg cggggggccg aacggcgctg agggagccct ccggaccccc tcggtgctgg
    15121 gataccgctg cggggagacg cccggcgctg atcgtcaacg ccccgtcgcc catcgtcaag
    15181 gacagggcgg ggaaagatcc gcagactgat gggcgtcggg atgcccggtg ccacgggggt
    15241 gcgccgtgcg cccgacccaa caccaccgct ccaccgcacc ttcgtgtgcg cacgaggtgg
    15301 tgagcagggt cggttcgccg ccggcacggg ggatccggag cgcagtgccg agacaccgac
    15361 cgtgtccccg gccgctcagc gcaccaccgg ctctgtccgc ccccggagcc tggtgtgccg
    15421 gtagtcactg ggtgacatgc cctggtcggc tctgaacaca cggctgaagt gggcgggcac
    15481 gccgaagccg caccgcgcgg cgatcgtctg caccggtgtg tcgaggagat gggggtcggc
    15541 gaggtcccgg cgggcccgtt cgaggcgtcg gctccggatg agggcggcca ccgtggtgcc
    15601 ctcctgctgg aacagccggt gcaggtggcg ggtcgatatg tggtgcgcgg cggcgacggc
    15661 cgccggggtg agcttggggt cgtggaaatt gcggccgatg aaggagcgga tggtcaggac
    15721 gaggttgcgg gtacgggcct ccggcgacag ggccgcctcc cggtcgagcc caccggcgag
    15781 cagtccggcc gccagatcga gcaggacccg gtgcagccgg gccgcgtcgg cggggccgta
    15841 gacgtccgcc gggtccacca gatgggtgac gaactgggtg agcagcgcgc cgaagccgtg
    15901 ccggccggac agccgccggc ccagcacgtc gtccaggggc acgctcgccg gaaggggcaa
    15961 cagcgatcgg gggaggtcca cccccacccc cacgatcggc tcgtcggcgg tccggacgtc
    16021 acagggtctg gacatgtcga ggacatagag gtcgtgcgtt tcggccgtac tgcgcagccc
    16081 gccctgttcg acgtacaggg ccccgctgcc gggccggacc agcgtcatgt ggagcagacc
    16141 cgggtcggac tgtctgatca gccggggcgt acgccggtag cgggacgcct gcaggcggac
    16201 gggccacagc agggtgtcct caacacgcag gagccggtgg tcggcccaga agtcgtcggc
    16261 gtacgggctg gtgatctcca tgggcgcgat gacgttgttc acgcactgct gccagccggc
    16321 gaaccggtcg ctccgctgga gggcatcggt ccggaatacc gcttcggtca gcacacgccg
    16381 cccctctttc gttccgcgcg gccccgtccc gtaccgccgt gctcttcagg atcttgcatc
    16441 agcgacggcg caacaacatg cgtcgccggt ggacttggcc gcgggctgat ccgccgggaa
    16501 caccgcgcgc ctcttgccag cacccccggc cgcctgcatt actgctccca ggaagatcga
    16561 ccgaatgatc ggtcgcctcc ccttcgcggc ccgttcgtca cctgccggtc gcctgtttcg
    16621 gaaggaaggg tcctgatgac ggccatgctg gacgcgacgg aacggctcgg ccgtggcgaa
    16681 ctggaggccc tgcaactgga gcggctccgg tccacgctgc gccacgcgta cgacgccgtc
    16741 cccttctacc ggagcgcctt cgacagcgcg gggctgcggc ccgacgactg ccggacgctc
    16801 gcggacctgg cccggttccc gttcaccgtg aaggccgatc tgcgggacaa ctacccgttc
    16861 gggatgttcg ccgtgccgga acacgaggtg cgcaggatcc acgcctccag cggcacgacc
    16921 ggacgtccga cggtcgtcgg gtacaccgaa cgggacctgg acacctgggc ggacgtggtg
    16981 gcccgttcga tccgggccgc gggcgggcgg cccggccaca aggtccatgt ggcgtacgga
    17041 tacgggctgt tcaccggcgg actcggggcg cactacgggg cggagcggct cggctgcacc
    17101 gtgatccccg cgtccggggg catgaccgcg cgccaggtcc ggttgatcca ggacttccgg
    17161 cccgagatca tcatgatcac gccgtcgtac atgctgacac tgctggacga gttcgagcgg
    17221 cagggcgtcg atccgcgttc gacgtccctg aaggtcggga tcttcggcgc ggagccgtgg
    17281 accgagggga tgcgccggga gatcgaggac cggttcgcca tcgacgcggt cgacatatac
    17341 gggctctccg aggtgatggg cccgggggtc gcgcaggagt gcgtggagac aaaggacggg
    17401 ctgcacatct gggaggacca cttctacccg gaggtcgtgg acccgctcac cggtgaggtg
    17461 cttcccgacg gcgaggaggg ggagctcgtc ttcacctcgc tgaccaagga ggcgatgccg
    17521 gtgatccgtt accgtacccg ggacctgacg cggctgctgc cggggacggc gcggacgttc
    17581 cgccggatgg agaaggtcac cggacgcagc gacgacatgg tgatcctgcg cggggtgaac
    17641 ctctttccca ctcagatcga ggagatcgtg ctgcgtacgc ctgccgtcgc tccgcatttc
    17701 cagctgcggc tgacccggca gggccggctc gacgcgctca ccgtccgggc ggaggcgcgg
    17761 acggacgcca cggcggccga ccgggagaag gccgccctgg ccatcgcggc ggcggtgaag
    17821 gacggtgtcg gggtgtcggt gggggtcgag atcgtggacc cggagtcgct ggaacgctcg
    17881 gtgggcaaga tccggcggat cgtggatctt cgggcgtcgg gcaccgagta gcacagccgg
    17941 gagcgtgtcc ggccgttcgt gcggcggatc gtggatgcgg gtcggttgcg gcggccggtt
    18001 ccgggaagcg gtccggtcgc ggggagcggt ccggtttccg ggatgcggtc ggtcaccgga
    18061 agcggccggt tcctggaaac ggccggttcc tggaagcggc cggtctcagg ccagctcgtc
    18121 ccgcagttgc cgcttgagga tcttcccgct ggcgttgcgc gggagcgact ccacgaacac
    18181 gacgcgcttg ggcgccttga acgcggtgag cttctcgcgg gcgtgggcga tgagttcact
    18241 ctcgcccgcc tcgccgcgca ggacgacgac ggcggtgacg gcctcgatcc agcggtcgtc
    18301 gggaaggccg atgacggcgg tctcggcgac ggcggggtgg gtgtagaggg cgtcctcgac
    18361 ctggcgggag gcgacgagga cgccaccgga gttgatgacg tccttgaccc ggtcgacgac
    18421 ggtgaggtag ccctcggcgt cgcggacggc gaggtcgccg gagtggaacc agccgtcgcg
    18481 gaaggcctcc gccgtctcct cgggcttgtc ccagtagccg gagcacagtt ggggcgagcg
    18541 gtagacgacc tcgccggggg tgccgtcggc gacctcctcg cccttctcgt cgacgacccg
    18601 ggcctccacg aacaggaccg gccggccgca ggactccatc cggccctcgt gctcgtcggg
    18661 gcccagcacg gtggccaggg ggccgatctc gctctggccg aagcagttga agaaggccag
    18721 gtgcgggagg tgctcgcgca gccgctccag gacggggacg ggcatgaccg aggccccgta
    18781 gaacgccttg cgcagtccgg cgaggtcgcg ggtggcgaac tccgggtggt tggcgagacc
    18841 gatccagacg gtgggcgggg cgaacaggct gtcggccagg cccgcttcga cgaggtcgaa
    18901 gaccgtggcg gcgtccgggg cgtccaggat ggtgttctcc gcgccgaccg ccaggtaggg
    18961 cagcaggaac acatgcatct gggccgagtg gtagagcggc agggagtgca cgggccggtc
    19021 gttcgcggcg aggccgagcg cggtgatcgc gctgacgtac tcgtggacca gggccccgtg
    19081 cgtcatcatc gcgcccttgg gcagcgccgt ggtcccggag gtgtacagga gttgcaccag
    19141 gtcgtcggag gcgggcgggc gccgcggggt gaacgcccgt tccgtctcca gggcgtcgag
    19201 cagcgacccg ggcgcgtcac gcagcgcccg caccggaggc ccggcgggga gccgcccggc
    19261 gaggtccggg tcggtcagca cgagggagga gccggactgg tcgaggaggt aggccaggtc
    19321 gtcgccggtg aggttctggt tgaccggtac atggacgaga ccggcccgtg cgcaggcgag
    19381 gaagccgatc agatacgcgt cggagttgtg cgcgtaggcg gccacccggt cgccgggggc
    19441 gagagcgtgc tcctcggtga ggacggcggc ggccgtggag acggcggcgt ccagggagcg
    19501 gtaggtccag gcccggccgg cgtaccgcac ggcggtcgct ccgggggtgc gccgggcgct
    19561 gcgggtgagg acgccgtcga ccgtgctgct gcgtacacct gtcatggcgt gatcctgtgc
    19621 gtccgggccc cgaaggtcaa gaggctggat accgaccgga cggttgacag gtcccggggc
    19681 tccctggctg agtggcgcgt ggctgtccgg acggtccggt caggccgccg cgccacccgc
    19741 accgctggga ggaacacctt gaccttacgt aaacgtctga gactgttcgg ggtcgccggt
    19801 ctcgccctgt tcaccgtgac ggcgtcgctg ccgccggccg ccgcgtccgg ggctcagccg
    19861 tcgcggcacc cgtccggggg cggtctctcc gccgtcatcc ggtacacgga gtacggcatt
    19921 ccgcacatcg tggcgaagga ctacgcggag ctcgggttcg gcaccggttg ggcccaggcc
    19981 gccgaccagg tgtgcacact ggcggacggc ttcctcacgg tgcgcgggga gcggtcgagg
    20041 ttcttcggcc cggacgccgc cacggaccac tccctctcct cggcggcgac gaacctctcc
    20101 agcgacctgt acttccgggg cgtccgggac agcggcacgg tggagaagct gctcaaggag
    20161 cccgcgcccg ccggtccgag ccgggacgtc aaggagacga tgcgggggtt cgccgccggg
    20221 tacaacgcgt ggatcgcgca gaaccggatc accgacccgg cctgccgggg cgcctcctgg
    20281 gtgcgcccgg tgacggccct ggacgtggca gcgcgcggct acgcgctggc ggtgctcggc
    20341 ggccaggggc gcggcatcga cggcatcacg gcggcgcgac cgccgaccgc cgctcccccg
    20401 gcggccgggg tcacgcccga ggaggcggcg acggcggcgg agcggctgct gtcgacgcag
    20461 aacgcggaca tgggttccaa cgcggtggcc ttcgacggct ccaccacggt gaacgggcgc
    20521 gggctgctgc tcggcaaccc gcactacccg tggcagggcg gacgccggtt ctggcaggct
    20581 cagcagacga tccccggcga gctgaacgtg tcgggcgcgt ccctgctggg ctcgacgacg
    20641 atctcgatcg ggcacaacgc cgatgtggcg tggagccata cggtcgccac gggcgtcacg
    20701 ctgaatttgc atcagctcac cctcgatccg gccgacccga ccgcctatct ggtggacggg
    20761 aagcgggagc gaatgacacg gcggacggtg agtgtcccgg tgaagggggc ggccgacgtg
    20821 acccgcaccc agtggtggac ccgctacggg ccggtggtca cctcgatggg tccgacgctg
    20881 ccgctgccgt ggacggcgag cacggcgtac gcgctgaacg acccgaacgc gacgaacatg
    20941 cggatggcgg acaccggtct gggcttcggc aaggcccgct ccacgggtga cgtcgagcgt
    21001 gcgctgcacc ggtcgcaggg catgccgtgg gtgaacacga tcgcggcgga ccgggcgggg
    21061 cactcgttct tcgcccagtc gcaggtgctg ccgaggatca cggacgagct ggcggagcgc
    21121 tgctcgaccc cgctggggcg ggccacgtac cccgcttccg gtctcgcggt gctggacggt
    21181 tcgcgggcgg actgcgcgct gggcagcgac cccgacgcgg tgcggccggg gatcttcggc
    21241 cccggccgga tgccggtgct gaagaaccag ccgtacgtgg agaactccaa cgacagcgcg
    21301 tggctgacca acgcggagcg gccgctgacc gggtacgagc gggtcttcgg cacgatcgcg
    21361 acgccccggt cgctgcggac gcgcggtgcg gtcgaggacg tcgcgtcgat ggcggaccgg
    21421 ggccggctcc gggtcgcgga ccttcagcgg cagcagctcg ccaaccgtgc gccggccggg
    21481 gatctggcgg cgtccgaggc ggcgaagtgg tgtgcggcgc tgccgggcgg cacggccgtg
    21541 gggtcggacg ggacgcgggt cgacgtgtcg gcggcctgcc gggtgctgcg gcgctgggac
    21601 cggagcgtgg acagcgacag ccggggcgcg ctgctcttcg accggttctg gcggaaggcg
    21661 tcggcggcgc ccgccgccga gctgtggagg acaccgttcg atccggcgga cccggtgcgc
    21721 accccgcgcg acctgaacac tgccgcaccc gtcctgggcc gggccctggc ggacgccgtg
    21781 gcggagctgc gggcggcggg catcgcgctg gacgcgccgc tgggcgagca ccagttcgtc
    21841 gtgcggaacg gcaagcggct cccgatcggt ggcgggacgg agtcgctggg cgtctggaac
    21901 aagaccgagc cgcggtggga cgcggcggga ggcggctata cggaggtgtc gtcgggctcc
    21961 agctacatcc aggcggtcgg ctgggacgac agccgctgcc cggtggcccg gacgctgctg
    22021 acgtactccc agtcggagaa ccccaagtca cctcactaca gcgaccagac caggctgtac
    22081 gcgggggagc gctgggtgac gtcgcggttc tgcgagcggg acatcgcgcg ctcaccggat
    22141 ctgcgggtgg tgcgggtgcg cgaacggcgc tagggcgggc tcgtccgggc cggacgccct
    22201 gcgccgaggg cgat
//
