LOCUS       NZ_CP094446            21863 bp    DNA     circular CON 31-MAR-2024
DEFINITION  Paenibacillus thiaminolyticus strain Mbale2 chromosome, complete
            genome.
ACCESSION   NZ_CP094446
VERSION     NZ_CP094446.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus thiaminolyticus
  ORGANISM  Paenibacillus thiaminolyticus
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 6487160)
  AUTHORS   Hehnly,C., Shi,A., Ssentongo,P., Zhang,L., Isaacs,A., Morton,S.U.,
            Streck,N., Erdmann-Gilmore,P., Tolstoy,I., Townsend,R.R.,
            Limbrick,D.D., Paulson,J.N., Ericson,J.E., Galperin,M.Y.,
            Schiff,S.J. and Broach,J.R.
  TITLE     Type IV Pili Are a Critical Virulence Factor in Clinical Isolates of
            Paenibacillus thiaminolyticus
  JOURNAL   mBio 13 (6), e0268822 (2022)
   PUBMED   36374038
REFERENCE   2  (bases 1 to 6487160)
  AUTHORS   Zhang,L. and Hehnly,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAR-2022) Institute for Personalized Medicine,
            Pennsylvania State University College of Medicine, 500 University
            Dr, Hershey, PA 17033, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 05-APR-2021
            Assembly Method :: Canu v. 08/2018; Pilon v. 08/2018
            Assembly Name                     :: PSU_P.thiaminolyticus_Mbale2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 40.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028554415.1-RS_2024_03_31
            Annotation Date                   :: 03/31/2024 07:15:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,889
            CDSs (total)                      :: 5,780
            Genes (coding)                    :: 5,579
            CDSs (with protein)               :: 5,579
            Genes (RNA)                       :: 109
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 201
            CDSs (without protein)            :: 201
            Pseudo Genes (ambiguous residues) :: 0 of 201
            Pseudo Genes (frameshifted)       :: 146 of 201
            Pseudo Genes (incomplete)         :: 68 of 201
            Pseudo Genes (internal stop)      :: 17 of 201
            Pseudo Genes (multiple problems)  :: 26 of 201
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:53:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2976107
            Orig. end                         :: 2997970
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP094446.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Bacteria and source DNA
            available from Schiff/Broach Lab, 500 University Drive Hershey, PA
            17033.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21863
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="9"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21863
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21863
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11863](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11863)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(279..656)
                     /locus_tag="L3476_RS13325"
                     /old_locus_tag="L3476_13320"
     CDS             complement(279..656)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679746.1"
                     /locus_tag="L3476_RS13325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13320"
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="WP_272828429.1"
                     /transl_table=11
                     /translation="MRKMKKLPDAEFDIMRVVWANEPPITTAMIMDQLGNERQWKAPTV
                     ISLMMRLVERGFLQTEKEGKERTYYPLIRKEDYLALETQHFLKQYHENSFLSFVNTLYN
                     GKRLTEKELDELLTWAKERRE"
     misc_feature    662..677
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.86"
                     /tool="antismash"
     misc_feature    695..710
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 21.31"
                     /tool="antismash"
     gene            complement(876..1259)
                     /locus_tag="L3476_RS13330"
                     /old_locus_tag="L3476_13325"
     CDS             complement(876..1259)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679745.1"
                     /locus_tag="L3476_RS13330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13325"
                     /product="hypothetical protein"
                     /protein_id="WP_272828430.1"
                     /transl_table=11
                     /translation="MKLGKKTIAGLVAVVACFSMSTAAFANTQEVDATGYGKLTGTLSG
                     KNYTTKVSQNRDNAYLTVGGTIQDINGNTLVRQQEIRSSRGATILSGSWNSLPSKAYAI
                     YGVHGVQGGNTYGAQAVYTYTHV"
     misc_feature    1446..1455
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.48"
                     /tool="antismash"
     gene            1582..2160
                     /locus_tag="L3476_RS13335"
                     /old_locus_tag="L3476_13330"
     CDS             1582..2160
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679744.1"
                     /locus_tag="L3476_RS13335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13330"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_272828431.1"
                     /transl_table=11
                     /translation="MEQWLSFLQRKFQHLDRSSQELTYQSYREFIYRDIYFLLQNHQLT
                     EDVIQESFLKVIASSPTSKNAANMKAWLKKIARNTAYDYLRKDKKYEYLSNLESIEEKE
                     LFSSEAETAVADQVEEQIRDEMLHEALDQLNARYRNVLFRYYVEDKSHRELARELGISE
                     QASAQLLVRARKKLRYYFCKRWVDREEKR"
     gene            2540..3970
                     /locus_tag="L3476_RS13340"
                     /old_locus_tag="L3476_13335"
     CDS             2540..3970
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (154-450). E-value:
                     7.1e-16. Score: 50.2. Matches aSDomain:
                     nrpspksdomains_L3476_RS13340_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010502431.1"
                     /locus_tag="L3476_RS13340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13335"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_272828432.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 7.1e-14, bitscore:
                     50.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTINRNDDRPIWQQLLDQAIHNITAGNWPPGQLLLPSRELAHLL
                     GVSRSTIQIVYEELFSRGYTVTSRRGGTRVSEWKQAAGPEADTVTAGPALPELPFLDAA
                     VDHLHHWLGDSGPCQVDINFSPHEPFLDERFHHIWRQSFLQAAAGIDASSWAYGDPCGY
                     LPLREQIQRYLSLERGIHVGVNQILLTSGAQHSLDLIAQSLLREGDTVTVEDPGFPAAW
                     MAMAYRGMNVVPAPVDEYGLQVDRVPPQSKLVFVTPSHQCAVGVIMSEPRRQQLLHLAA
                     SAPCWIVEDDYDSEFRYRGTPLPTLFSQLPRNTLYMMSFSKMIAPGIRLSAIVGSEEAI
                     SRLVRVHRLTYRHLPMMEQLTLAHFIARGHFMRHMRRVRNVYRRRHEAMTKAIMASGLG
                     GRFKLSGVETGSHMLLEAGDTYDEQAATRSALEQGIRVYPLSSYCLASNRKGWVLGFPN
                     VDEAAIQQGISRLAGILL"
     aSDomain        3002..3889
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_L3476_RS13340_Aminotran_1_2.1"
                     /evalue="7.10E-16"
                     /label="L3476_RS13340_Aminotran_1_2.1"
                     /locus_tag="L3476_RS13340"
                     /protein_end="450"
                     /protein_start="154"
                     /score="50.2"
                     /tool="antismash"
                     /translation="WAYGDPCGYLPLREQIQRYLSLERGIHVGVNQILLTSGAQHSLDL
                     IAQSLLREGDTVTVEDPGFPAAWMAMAYRGMNVVPAPVDEYGLQVDRVPPQSKLVFVTP
                     SHQCAVGVIMSEPRRQQLLHLAASAPCWIVEDDYDSEFRYRGTPLPTLFSQLPRNTLYM
                     MSFSKMIAPGIRLSAIVGSEEAISRLVRVHRLTYRHLPMMEQLTLAHFIARGHFMRHMR
                     RVRNVYRRRHEAMTKAIMASGLGGRFKLSGVETGSHMLLEAGDTYDEQAATRSALEQGI
                     RVYPLSSYCLASNRK"
     gene            complement(4021..4764)
                     /locus_tag="L3476_RS13345"
                     /old_locus_tag="L3476_13340"
     CDS             complement(4021..4764)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009675145.1"
                     /locus_tag="L3476_RS13345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13340"
                     /product="YggS family pyridoxal phosphate-dependent enzyme"
                     /protein_id="WP_272828433.1"
                     /transl_table=11
                     /translation="MSAIIEDNLKAVRRRMELACLASGRQKEEVKLLLATKTVPLDKLQ
                     SAIRAGETLLGENKAQELRGKYADMQQYKQVEWHFIGHLQTNKVKDVVKYVTMIHSVDR
                     FKLGHALHNQLRKENKTMDILVQINTSYEESKFGARPEEALELVEQLSQFDTLNIKGLM
                     TIGKLNATSAETRHCFRLLKQIQTQIIAKNIPGVEMDVLSMGMSGDFEVAIEEGATIVR
                     IGTGIFGERYLPDSYYWNEKAGSHD"
     gene            complement(4909..5124)
                     /locus_tag="L3476_RS13350"
                     /old_locus_tag="L3476_13345"
     CDS             complement(4909..5124)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="L3476_RS13350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="L3476_13345"
                     /product="hypothetical protein"
                     /protein_id="WP_272828434.1"
                     /transl_table=11
                     /translation="MNIRLRSKKTIEATAVEVIEDESTERMLTLITCDDSGKARVLTRG
                     RFVGKKPIQEATKEMKEAFQLEMSNL"
     gene            complement(5090..5506)
                     /locus_tag="L3476_RS13355"
                     /old_locus_tag="L3476_13350"
     CDS             complement(5090..5506)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016119.4"
                     /locus_tag="L3476_RS13355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13350"
                     /product="class A sortase"
                     /protein_id="WP_272828435.1"
                     /transl_table=11
                     /translation="MGLDKVAAAGEEKRDNSHVRKQEPTFHFEEVAELDFETILMANLH
                     KDEIHVIGGISIPSVDMNLPIGEGVAPYTLALTAGTMKPGQVMGEGNYALAGHHMNRKD
                     LLFSPLLQVQTGTAAYLTDMQYIYEYQIEEQKND"
     gene            complement(5496..5639)
                     /locus_tag="L3476_RS13360"
                     /old_locus_tag="L3476_13355"
     CDS             complement(5496..5639)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="L3476_RS13360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="L3476_13355"
                     /product="hypothetical protein"
                     /protein_id="WP_272828436.1"
                     /transl_table=11
                     /translation="MATKKRTAARIIYNAVCAAVLLAGIVMLLHEPIQGWFVSRGDELI
                     GA"
     gene            5904..6710
                     /locus_tag="L3476_RS13365"
                     /old_locus_tag="L3476_13360"
     CDS             5904..6710
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679741.1"
                     /locus_tag="L3476_RS13365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13360"
                     /product="DUF817 domain-containing protein"
                     /protein_id="WP_272828437.1"
                     /transl_table=11
                     /translation="MAFKLTSFVEFGWQQALSCLFPAIIFAALALTRVIDIPYIPAYDF
                     MLLICLAVQIIMIRSRLETMDELKVICVFHLIGLVLEIYKVHMGSWAYPLDGWTKVFGV
                     PLYSGFMYASVASYLCQAWRRLQVKLHRYPKPWCTVPLGAAVYLNFMTHHYIYDLRWVL
                     TILLFAVFFRTYVEYTVLGVTRRMPLVLSFGLIGFFIWVAENIGTFLGAWRYPHQANGW
                     NLVQLGKFSPWFLLVIVSFMIVAQLKHVKEGRSHRSQSIEQPLQMP"
     gene            6809..7285
                     /locus_tag="L3476_RS13370"
                     /old_locus_tag="L3476_13365"
     CDS             6809..7285
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679740.1"
                     /locus_tag="L3476_RS13370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13365"
                     /product="DUF2975 domain-containing protein"
                     /protein_id="WP_272828438.1"
                     /transl_table=11
                     /translation="MLRRNTAFLKLAIAMIGITALILSIFWLPGFVTSRAAEYPDYISL
                     KYPVLVVVYTTSIPFYIALYQSYKLLQYIERKHAFSDLAVASFKRIKQCAVAIAIIYAI
                     GGAFLGFQSVLLTSIALIGAVIIFAAFTVAIFAAVLQELLTHALAIKSENDLTV"
     gene            7295..7510
                     /locus_tag="L3476_RS13375"
                     /old_locus_tag="L3476_13370"
     CDS             7295..7510
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679739.1"
                     /locus_tag="L3476_RS13375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13370"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_087441664.1"
                     /transl_table=11
                     /translation="MAIIINIDVMLAKRKMSVTELSEKVGITMANLSILKNGKAKAVRF
                     STLEKICEVLDCQPGDILEYVQEDPS"
     misc_feature    7304..7318
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 20.1"
                     /tool="antismash"
     gene            complement(7598..8920)
                     /locus_tag="L3476_RS13380"
                     /old_locus_tag="L3476_13375"
     CDS             complement(7598..8920)
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003213381.1"
                     /locus_tag="L3476_RS13380"
                     /note="This protein belongs to a clade of FMN-dependent
                     monooxygenases, within a broader family of flavin-dependent
                     oxidoreductases, the luciferase-like monooxygenase (LMM)
                     family, some of whose members use coenzyme F420 rather than
                     FMN.; This protein belongs to a clade of FMN-dependent
                     monooxygenases, within a broader family of flavin-dependent
                     oxidoreductases, the luciferase-like monooxygenase (LMM)
                     family, some of whose members use coenzyme F420 rather than
                     FMN; Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /old_locus_tag="L3476_13375"
                     /product="NtaA/DmoA family FMN-dependent monooxygenase"
                     /protein_id="WP_272828439.1"
                     /transl_table=11
                     /translation="MTAHRQLCIGFTLSATWMKGHGWRRSDSGVEKMGSIDYYIEVAKM
                     AEEAKLDFLFRADYLYMSPQMLGDSANFGSPDPTMMFAAIARETERIGLVTTVSTTFNP
                     PYIVARQLQSLHWLSNGRAGWNIVTSIEGAENFGDSSMPSPQERYARAREFTDVVRKLW
                     ASFPHEAIVIDRESGKFSDPDQVSPIHHSGEFFSVKGPLTLPAHPSGSIPLFQAGASDT
                     GRYFAASIADAIFAAMPDLESGVELRHDLRRRAEAHGRDPDAIKVLPGLYFFLGETREE
                     AHALYQAAHAHLSVERRQASLQSVLGLDVSGLALDHRVTADMMPDPNQPVRSRTHAGLL
                     RRYITAYQPTVAEVLARPEVTGSAHWVAVGTVEDVLNDIMERFEAGAIDGFIALPGGSE
                     QSMELFFEKLMPQLVERGLFRREYTGSTLKDHLGMQHLSLE"
     misc_feature    complement(8954..8968)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.86"
                     /tool="antismash"
     misc_feature    8957..8972
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.08"
                     /tool="antismash"
     misc_feature    complement(8960..8975)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 26.07"
                     /tool="antismash"
     misc_feature    8963..8978
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 23.56"
                     /tool="antismash"
     misc_feature    8965..8979
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.06"
                     /tool="antismash"
     gene            complement(9097..9909)
                     /locus_tag="L3476_RS13385"
                     /old_locus_tag="L3476_13380"
     CDS             complement(9097..9909)
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017250795.1"
                     /locus_tag="L3476_RS13385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13380"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_272828440.1"
                     /transl_table=11
                     /translation="MVDVERLAGVFANDPYNIEDVYRLVIQPKSILREFRTVRHGFLFA
                     VRGQARICVNGTVYDLHPGILFHAAPGMQLESRVIGQSELEYYSVFYRLDMSGEDNRDH
                     ECNTHFKLEPGANPRVIELLTMLHQNAQTLGGIGKLRVKELFLSILHQVLVGHKHRMTS
                     HVPSKRVIEEATEYMKRHYMNPLTLEEMAELHAMSPKSFSYFFHKYTGVRPIDYLINYR
                     MERASELLKADIFPIRDIAVSVGYANPLYFSRAFKKKFGMSPSAYADQ"
     gene            complement(10001..11863)
                     /gene="shc"
                     /locus_tag="L3476_RS13390"
                     /old_locus_tag="L3476_13385"
     CDS             complement(10001..11863)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010281982.1"
                     /locus_tag="L3476_RS13390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13385"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_272828770.1"
                     /sec_met_domain="T2TS (E-value: 6.3e-104, bitscore: 346.8,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDTVTGIGWIIETLRKEQSPDGAWAYPFDTGISTDAYMIILLRT
                     LEIDDEELVEGLCRRILSKQQQNGAWKLFYDEGEGNVTSTVEAYYGLLFSGLYRKEDER
                     LRAAKKFILAHGGLSEVSMFTKIMLALTGQFQWPSFTPLPIEMILLPLNFPINFYSFSV
                     FGRANLTPIMILADQKFSMKTVYAPDLSDLKWSREDEEQWGRSKEWRSLLSCIQDGVNR
                     LIGIPRELRRLALERARTYMLDHLEQDGTFYSYYSSTFLMIFALLSLGYKKTDPIITKA
                     VEGIRAMKCEINGLPHMQYTTANVWNTSLIGYTLQAAGVSHEDPMVTKANKYLLSRQHY
                     RFGDWVVHNPSGMPGGWGFSDVNTMNPDVDDTTASLRSISTIASQHPTTWARGISWLLP
                     MQNDNGGWPAFEKNTDSKVLEVLPLEKGRFLLLDPPCADLTGRTLEFLGNYTNLPASHS
                     VIRNAVHWLLKDQRKDGSWYGRWGICYIYGTWGAVTGLKAVGVAKNHPSMQKAAAWLRS
                     IQNADGGWGESCRSDIQMTYVPLKTSTLTDTAWALDALIAIADRPTTAIQKGITFLLDS
                     LEKEDWTTDYPKGQGMGGAFYIHYHSYRYIFPLLALAHYRRKFE"
     gene            11959..13080
                     /locus_tag="L3476_RS13395"
                     /old_locus_tag="L3476_13390"
     CDS             11959..13080
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007087169.1"
                     /locus_tag="L3476_RS13395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13390"
                     /product="DUF2515 domain-containing protein"
                     /protein_id="WP_272828771.1"
                     /transl_table=11
                     /translation="MRKRHKTPLETIREELKKRKKHSPATLNELTLSEKKLLNKIKGIT
                     QDHNLNNLTRTKAYLEFYLRHPEIHWAFLGHMVSRNGGWNMTDLKGEFLATLLAKEERE
                     SFFHFLERGNWLIFQDAYPQFLLYDESLRQNRPMFYLLPHLNVSIFMETVWNYFWRVRD
                     TYILCIALVINEQSYLEQRVIQNPHYQKEVLHKIEFHLQNWLSFNQILFPSEGENVKGQ
                     TLHQFQSLHERILLGKRLYAILFKNKDFHRQALDWATRQPHTGSRKDYWPHLFNDVNEG
                     TPGITYPLRFKSCRLRKGARRIYSPKLEYAWKNVSQPEAEPGDWFQHISVVDYLEDDQE
                     MTDGEIKNDYCNTLERLEIAALAKKTIHFLEQR"
     gene            13001..13453
                     /locus_tag="L3476_RS13400"
                     /old_locus_tag="L3476_13395"
     CDS             13001..13453
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004436593.1"
                     /locus_tag="L3476_RS13400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13395"
                     /product="CBO0543 family protein"
                     /protein_id="WP_240927684.1"
                     /transl_table=11
                     /translation="MTTATHWSGSKLPRSPKKRFTFWNKDSLACAVLGSLLGTYLDLYF
                     VGKGLYHFPYRLLPEIFSIHIVFTLIGLPILTMIFLYCISQANRWGRVGIIICVSLLMP
                     IFEKIAERLGVFVHSDKWMHLYSFFGYLLFFTIISGVYFWLRKKSG"
     gene            13603..14460
                     /locus_tag="L3476_RS13405"
                     /old_locus_tag="L3476_13400"
     CDS             13603..14460
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007131902.1"
                     /locus_tag="L3476_RS13405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13400"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_240927683.1"
                     /transl_table=11
                     /translation="MILRLLLFVLAMLSVLSGCAQNQAQQKPGSNPYSSSAPQPPQILQ
                     NSVRSSTPDLADGPEGNLREPHALSLADLRAKYPSTFILHGPGTKREIALSFDDAPDDN
                     FTPKVLDVLKSEGVKATFFVVGNRIEKHPDIVKRIVEEGHILGNHSYNHANLPKLSDAE
                     FRDQIMKTDQLIREHTGYTPNIVRPPYGNISENQIKWLASQKKKVTNWNVDSLDWKGLD
                     AEEVKTNVLAHVSPGAIILQHSAGGTGQDLSGTVLALPDIIRTLKNDGVKLVTIPELLD
                     LNVK"
     tRNA            complement(14569..14650)
                     /anticodon=(pos:complement(2990722..2990724),aa:Leu,
                     seq:caa)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="L3476_RS13410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="L3476_13405"
                     /product="tRNA-Leu"
     gene            complement(14569..14650)
                     /locus_tag="L3476_RS13410"
                     /old_locus_tag="L3476_13405"
     tRNA            complement(14665..14741)
                     /anticodon=(pos:complement(2990812..2990814),aa:Arg,
                     seq:acg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="L3476_RS13415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="L3476_13410"
                     /product="tRNA-Arg"
     gene            complement(14665..14741)
                     /locus_tag="L3476_RS13415"
                     /old_locus_tag="L3476_13410"
     tRNA            complement(14749..14823)
                     /anticodon=(pos:complement(2990896..2990898),aa:Gly,
                     seq:gcc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="L3476_RS13420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="L3476_13415"
                     /product="tRNA-Gly"
     gene            complement(14749..14823)
                     /locus_tag="L3476_RS13420"
                     /old_locus_tag="L3476_13415"
     gene            complement(15058..16077)
                     /locus_tag="L3476_RS13425"
                     /old_locus_tag="L3476_13420"
     CDS             complement(15058..16077)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679446.1"
                     /locus_tag="L3476_RS13425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13420"
                     /product="asparaginase"
                     /protein_id="WP_143799043.1"
                     /transl_table=11
                     /translation="MVDLGKVLVEEYRGNWLECAYTGHMVGVNEQGEPLFSVGDENYVS
                     FMRSSSKPVQALPALMAGVPEHYGLSDEEIVLMTASHRAQQFHVEALESFMRKTGISES
                     QFVCKPTYPLNGAARDELIAHGKPARSIYHNCSGKHLGVLALCKMKGWPTENYAEQNHP
                     VQQQVLSLMSALSDVPVEQIRLGTDGCGFPVYALPIRNIATLYLRLACPDLIPDEAIRA
                     AVIRLTTLMNRYPFYVSGTQLICPTLLQDDNIVAKGGAKGIYCFGLRKERMGIAFKVMD
                     GSEDQWPLIAAHILKEIEYSNVETIERLRQLSPPETKNDNGRVVGMREAKFELKWVKK"
     gene            complement(16119..18101)
                     /locus_tag="L3476_RS13430"
                     /old_locus_tag="L3476_13425"
     CDS             complement(16119..18101)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679445.1"
                     /locus_tag="L3476_RS13430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13425"
                     /product="alpha-amylase family protein"
                     /protein_id="WP_272828441.1"
                     /transl_table=11
                     /translation="MRYRQVHLDFHTSEHISDIGRNFSKKNFQEMLQLGHVDSITVFAK
                     CHHGWAYFPSATNEIHPGLDFDLLGAQIEAAHEIGVKVPIYISVGFDEKLAWEKPQWLM
                     RDEADRMNWVDSFMKPGYHQFCLNTPYLELVIKQVQEVVRKYDGDGIFLDIVGERTCYC
                     TTCLKQMQADGLDPHNKEDVIANGRRIYANYTTRIREAIDAIKPGLPVFHNAGHIHQGR
                     RDLMGMNSHLELESLPTGGWGYDHFPLSARYAQPTGFHFLGMTGKFHTFWGEFGGYKHP
                     NALRYETALSLANGARCSIGDQLHPGGQMDRATYELIGKAYAEVEAKEAWCVNAVNHAD
                     VALLTVEAAGVQQESGAMYSGKVDMGAVRMLLEGKILFDIVDMESDWSGYKVLILPDSI
                     VMKDTILPKVEAFLAAGGKVLASGRSGLNVELTRQMLPLGFTDSGLNPFRPDYFRPLCD
                     GMANLGEAAYVMYGEGRRIELTDGIELGRREDPYFNRQAFRFCSHQHAPSSEQDGGPGM
                     VESAQGIYIAWNVFEDYATKGSLILKEMVLFALRRLLGEQITLKTTLPAQGVTTLQHQA
                     AERRYINHLLYASPVKRGERVEIIEDMIPLQQVEVQLQLPVTGVKRVYLAPQMTEIGFK
                     ASGGDVQFTVPHLECHQMVVVEYNE"
     gene            18218..19090
                     /locus_tag="L3476_RS13435"
                     /old_locus_tag="L3476_13430"
     CDS             18218..19090
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679444.1"
                     /locus_tag="L3476_RS13435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13430"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_272828442.1"
                     /transl_table=11
                     /translation="MKLLSEVQPHIRAAHMYNYRGAPEEQRRRGYSYAFHLFTEGHGHM
                     IVNEQVYPVASGSLFFVRPGEGHYFVPAPGETMDACNIYCDLWCLPQPKQPTFAYQWDD
                     YDPRCLTEQMPCPELDALPTSMSLRPYPHLIELIKQTLAAFNRSGKYTAQAVSACFYSW
                     ILQWHEAGSLTETADYRITRILEQMEACPEQRFSVDYWCSECGLEKSQFYRLFKQETGM
                     SPKAYALQARMKKAAVLLMESRQSITDIALMLGYDSIHYFSNQFSSVYGVSPSSYRMGK
                     EYQKLDRWS"
     gene            complement(19124..20131)
                     /locus_tag="L3476_RS13440"
                     /old_locus_tag="L3476_13435"
     CDS             complement(19124..20131)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019421537.1"
                     /locus_tag="L3476_RS13440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3476_13435"
                     /product="phosphotransferase"
                     /protein_id="WP_272828443.1"
                     /sec_met_domain="APH (E-value: 1.1e-16, bitscore: 59.9,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARRISTARLRPFVRRYGLHLRHIQPCHSLYRRNAAFRAITDEGV
                     YVIKPFYRRKNTNLTTKQQIVSVTAYIHKLKAKHYPHLPHWLVTASGRYWVYQSGRPYY
                     MIEWVEGGNLQQGYHYEQLGRALATLHTICQADLPPMSPYTSRQISFFQDQDRLFRRRL
                     TMMRKRKGTAAWFREHGNQCIRLAEEAWRSIQRPVTQQVLRDEIRFPALIHGDVTFPNV
                     IMHSNGIYLIDWDQVRMDSTYYEIAKTLLNTTNFNPLLMGALLQGYELVRPLAAAERTL
                     IGSLFRLPVEAWAAARSAVNGQFQRLSRLLQNTWGERLAAIQWLDEWGRQSGQP"
     tRNA            complement(20259..20334)
                     /anticodon=(pos:complement(2996406..2996408),aa:Lys,
                     seq:ttt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="L3476_RS13445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="L3476_13440"
                     /product="tRNA-Lys"
     gene            complement(20259..20334)
                     /locus_tag="L3476_RS13445"
                     /old_locus_tag="L3476_13440"
     tRNA            complement(20338..20412)
                     /anticodon=(pos:complement(2996484..2996486),aa:Glu,
                     seq:ttc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="L3476_RS13450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="L3476_13445"
                     /product="tRNA-Glu"
     gene            complement(20338..20412)
                     /locus_tag="L3476_RS13450"
                     /old_locus_tag="L3476_13445"
     tRNA            complement(20430..20506)
                     /anticodon=(pos:complement(2996577..2996579),aa:Asp,
                     seq:gtc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="L3476_RS13455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="L3476_13450"
                     /product="tRNA-Asp"
     gene            complement(20430..20506)
                     /locus_tag="L3476_RS13455"
                     /old_locus_tag="L3476_13450"
     tRNA            complement(20565..20638)
                     /anticodon=(pos:complement(2996709..2996711),aa:Met,
                     seq:cat)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="L3476_RS13460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="L3476_13455"
                     /product="tRNA-Met"
     gene            complement(20565..20638)
                     /locus_tag="L3476_RS13460"
                     /old_locus_tag="L3476_13455"
     tRNA            complement(20645..20720)
                     /anticodon=(pos:complement(2996792..2996794),aa:Val,
                     seq:gac)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="L3476_RS13465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="L3476_13460"
                     /product="tRNA-Val"
     gene            complement(20645..20720)
                     /locus_tag="L3476_RS13465"
                     /old_locus_tag="L3476_13460"
     tRNA            complement(20733..20807)
                     /anticodon=(pos:complement(2996879..2996881),aa:Glu,
                     seq:ttc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="L3476_RS13470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="L3476_13465"
                     /product="tRNA-Glu"
     gene            complement(20733..20807)
                     /locus_tag="L3476_RS13470"
                     /old_locus_tag="L3476_13465"
     tRNA            complement(20812..20903)
                     /anticodon=(pos:complement(2996973..2996975),aa:Ser,
                     seq:gga)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="L3476_RS13475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="L3476_13470"
                     /product="tRNA-Ser"
     gene            complement(20812..20903)
                     /locus_tag="L3476_RS13475"
                     /old_locus_tag="L3476_13470"
     tRNA            complement(20907..20982)
                     /anticodon=(pos:complement(2997054..2997056),aa:Asn,
                     seq:gtt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="L3476_RS13480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="L3476_13475"
                     /product="tRNA-Asn"
     gene            complement(20907..20982)
                     /locus_tag="L3476_RS13480"
                     /old_locus_tag="L3476_13475"
     rRNA            complement(21032..21148)
                     /db_xref="RFAM:RF00001"
                     /gene="rrf"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="L3476_RS13485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="L3476_13480"
                     /product="5S ribosomal RNA"
     gene            complement(21032..21148)
                     /gene="rrf"
                     /locus_tag="L3476_RS13485"
                     /old_locus_tag="L3476_13480"
ORIGIN
        1 atagctgatg accccgccgc tgcggacacg gcttggcggg cggagccgcc gtccgacatc
       61 ttcagcgcag gcagcagcgt atcgagacga atcgccgaga catgcggatg aagccggaac
      121 ggaataatga atccgagtat gatgaccagc catccataat aacgtccttt tgccgtaaat
      181 gtcttcgcaa gcagcggggt aatcgccata tatagaaggg caatgacgga catcgtaatc
      241 gaacattcca gcaatgcaat cagaaatccc tgcaccggct actccctccg ttccttggcc
      301 catgtcaaca attcatccaa ctctttttcc gtaagccgct tcccgttgta caaggtattc
      361 acaaagctta aaaatgagtt ttcgtgatac tgcttcagaa aatgttgcgt ttctaaggcc
      421 agataatctt ctttgcgtat aagcggataa tacgtgcgtt ccttcccttc cttttccgtc
      481 tgcaaaaacc cccgttcgac caaacgcatc atcagggaaa tgacggttgg agccttccat
      541 tggcgttcat tcccgagttg atccataatc atggcggtcg taatcggcgg ttcattcgcc
      601 cacactaccc tcataatgtc aaattccgca tcaggcagct tcttcatctt tctcatccca
      661 ttttactcct ttttgacaat tgtcttacat aaagttttac acttgtcaaa aataaatgtc
      721 aataggtttt gcgaatattt tttacaattg cctaatatgt atttcccgtt ataaaaaaga
      781 agatgtttat accaagcaaa caaagtctag gcagacttca tccgcattgg tataaacatt
      841 cttctacgca gccattaccc tgctatcact tcagcttaca catgtgtgta agtgtataca
      901 gcctgagcgc cataggtgtt tcctccctgc acgccatgca ccccataaat agcataagct
      961 ttggaaggca acgagttcca ggagcccgat aaaatagtcg ctcctctaga actgcgaatt
     1021 tcctgctgcc ggacaagtgt attgccgtta atgtcttgaa tcgtccctcc gactgtcagg
     1081 tacgcattgt cacgattttg agagaccttt gttgtatagt ttttacccga taacgtaccg
     1141 gtcagtttcc cataacctgt tgcatccact tcttgagtgt ttgcaaacgc cgccgtagac
     1201 atggagaagc aagctacaac agcgaccaat ccagcaattg tctttttacc cagtttcata
     1261 gaaaaccctc ccactttgtt tttgaacatt accatgacct tgacttcaaa acttcctgca
     1321 gaactttaca ttgcatcaga cgttgcgggg gacacacacc tcctgcccgt tagatgatag
     1381 atgtaaagtc atgatgaagg tttctctata tagtagacgg attaatctac caaaatatga
     1441 cgaaatgatt ttttaatgta taaactagga aggattatga tgaatttcat agatcaatct
     1501 tcctttttag tatatattag tatatataga aaaaaagggc gagtcagaaa catatgcttg
     1561 ccagttcgtg gagggggcat tatggaacag tggttgtctt ttttacagcg taagttccaa
     1621 cacctggacc gctcatctca agaattgact taccaatcct accgggaatt catctaccgt
     1681 gacatttatt tcttactgca aaatcatcag ctgacggaag acgttatcca agaatccttc
     1741 ttgaaagtga ttgcctcatc gcctacatcg aaaaatgcgg ccaatatgaa ggcgtggctc
     1801 aaaaaaatcg cgcgcaatac agcctatgat tatttaagga aagacaaaaa gtatgaatat
     1861 ttatccaacc tggagagcat agaggaaaag gaactgttct cttccgaagc cgagacggcc
     1921 gtagccgatc aagtggagga acaaattcgc gatgaaatgc ttcatgaagc tcttgaccag
     1981 cttaatgcga gatatcgcaa tgtgctgttt cgctactatg tggaagataa gtcacatcga
     2041 gagctggccc gggaattagg gatcagcgag caagcttctg cgcaattatt ggttagggcg
     2101 cgcaaaaaat tgcgttacta cttttgcaaa agatgggttg atcgcgaaga aaaaagataa
     2161 tgtcttatgc gggagaggag acggcggcag cctcccggcg caagtaagca cacagccgct
     2221 ccccggttcc atcccgagaa gcggccgcag ctcctaaaaa acgcgaattc cctgctctcc
     2281 tccgtcaaag tgagaggaaa acagccaatc tctttttcgt tataatgaat gttcatgtct
     2341 actcccactc caatcggtca taccgctacc aaacgctccc ctgtatgcgg atactcccat
     2401 tctttcacgc taatatcttg ttcaacgcta ttcgttatgc tagtatcaac cattggaatg
     2461 gacgaacatg tccaatacat atctttttga ccaatccata ctagtttcgc aacccgtgtc
     2521 tgagccggag gtgaacggaa tgttgacgat taatcgcaat gatgatcggc ccatatggca
     2581 gcaactgctt gatcaggcga tccacaatat aacggcgggc aattggccgc cgggacaatt
     2641 gctgcttccg tcgcgggaac tcgcacattt gcttggcgtc tcgcgttcca ccatccagat
     2701 cgtgtacgag gagctgttca gccggggtta caccgtcacc tcccggcgcg gaggaacccg
     2761 cgtaagcgag tggaagcaag ctgccggccc ggaagctgat acggtaacgg cagggccagc
     2821 gctgcctgag cttccttttc tggatgcggc ggttgatcat ctgcaccact ggctgggaga
     2881 cagcggtccg tgccaggtgg atatcaattt tagcccccac gagccttttt tggacgagcg
     2941 ctttcatcac atatggcgcc agtcgttctt acaggcggct gccggcatcg atgcaagcag
     3001 ttgggcatac ggcgatccgt gcggctacct ccccttgcgg gaacagatac agcgctactt
     3061 gtcgctggaa cgggggattc acgtgggggt gaatcagatt ctgctgacct cgggcgccca
     3121 gcacagcctt gaccttatcg cgcaatcgct cttgcgtgaa ggagacacgg tcacggtcga
     3181 ggatcctggc ttccccgccg cctggatggc gatggcatac cggggaatga atgtcgttcc
     3241 cgctcccgtt gacgaatacg gcttgcaggt ggaccgcgtc ccgccgcaat ccaagctcgt
     3301 cttcgtgacg ccttcgcacc agtgcgcggt tggcgtcatt atgtcggagc cgcgcaggca
     3361 gcagctgctg cacctggccg cttcggctcc atgctggatt gtggaggatg attacgacag
     3421 cgaattccgt tatcgcggaa ctccgctgcc gacgctgttc agccagttgc cccgcaacac
     3481 cttgtatatg atgagctttt ccaaaatgat tgcccctggc attcggctct ccgccattgt
     3541 cggatcggaa gaagcgatca gccgtctggt ccgggttcat cgattgactt accggcatct
     3601 gccgatgatg gagcaactga cgcttgctca tttcatcgcc cgcggccatt ttatgcgcca
     3661 tatgagaaga gtccgcaatg tataccggcg cagacacgaa gcgatgacca aagcgataat
     3721 ggcaagcggc ttgggcggcc gattcaagct ctccggtgtc gagaccggct cgcatatgct
     3781 gctggaagcc ggggacacat atgatgagca agccgcgacc agaagtgcac tggaacaagg
     3841 cattcgcgtc tatcccctta gctcatattg cttggcaagc aaccgcaaag gatgggtgct
     3901 cggcttcccg aacgtagacg aagcggccat tcagcagggc attagccggc ttgcgggcat
     3961 actgctctag tatcgtcccg caagtcctcc ggctgtggcg ccaactatag gaagcatcgc
     4021 ttaatcatgc gaacccgctt tttcgttcca gtaataacta tccggcaaat agcgctcacc
     4081 gaatattccc gtccctatcc gaacgatcgt ggctccttct tcaatggcga cctcgaaatc
     4141 accggacatt cccatagaga gcacgtccat ctccacaccc gggatattct tggcgataat
     4201 ctgggtctgg atctgcttca atagccgaaa gcaatgccgg gtctcggcgc tcgtggcatt
     4261 cagcttgccg atggtcataa gcccctttat attcagcgtg tcgaattggg aaagctgttc
     4321 caccagttcc agcgcctctt ccggccgcgc gccaaatttg ctttcctcgt aggaggtatt
     4381 aatttgaacg agaatatcca tggttttatt ctctttccgc aattgattat gcagagcatg
     4441 acccaatttg aaccgatcga cggagtggat catcgtgaca tatttgacga cgtccttcac
     4501 tttattcgtc tggagatgtc cgataaaatg ccattccacc tgcttgtact gctgcatatc
     4561 cgcatatttg ccgcgaagtt cctgggcttt gttctccccc aataacgtct ctcccgcccg
     4621 gatcgcgctc tgcaatttgt caagcggcac ggtcttggta gccagcagca gcttgacctc
     4681 ttccttctgc cgcccggagg ccagacaagc caattccatt cgacggcgca ccgccttcag
     4741 gttgtcttcg attatagcgc tcacgttctc ccctcctgct tgctttcctt acaggcaaaa
     4801 attccatatt ttcagcttaa gcaaatttgg atgggttgaa cacgtccaaa gttggcattc
     4861 ttcgaggtcc ataatcgtta gccgccgatt cactcgcacc cctaatggct ataaattgct
     4921 catttccagc tgaaaggctt ccttcatttc cttcgtcgcc tcttgaatcg gcttcttgcc
     4981 gacaaatcgg cctctcgtca acacccgcgc cttgccgctg tcatcacagg tgatcaaggt
     5041 caacattcgt tccgtgctct catcctcaat gacttcgact gcggttgctt caatcgtttt
     5101 tttgctcctc aatctgatat tcatagatat actgcatatc ggttaaataa gctgccgtgc
     5161 ccgtttggac ttgcagcagc gggctgaaca gcagatcttt gcggttcata tgatgaccgg
     5221 ccagcgcata attgccttct cccataacct ggccgggctt catcgttccc gccgtgagcg
     5281 ctaacgtata cggggccacg ccttctccta tgggcaaatt catatcaacg ctcgggatgc
     5341 taatcccgcc gatcacgtga atctcatctt tgtgcaaatt cgccattaag atggtctcga
     5401 aatccagttc cgccacctct tcaaagtgaa aagtgggttc ttgcttgcgg acgtggctgt
     5461 tgtcccgctt ctcctcgcct gccgcagcca ccttgtcaag ccccaatgag ctcgtcccct
     5521 ctggagacga accagccctg gataggctcg tgaagcagca tgacaatacc ggccaagaga
     5581 acggcggcac agacggcatt atagattatc cttgcggcgg ttctcttctt tgtggccatt
     5641 cacgatcctc ccgagcgtgt ttctttccgc ttttattata agggacttct tcaagtagcg
     5701 acacctgaaa actagacaaa atctggacac atacaactta aacaataaat atttattgat
     5761 aaacgataaa tttttattga cgaagaggat gcgcacgatt atgataatac ctgtcgagcc
     5821 gcattggcgg ctcattcaag gtgccgttgc ggaggagcaa ctgtccttcc gtcagacgga
     5881 ttccaatgca ggaggaacct atcatggctt tcaagcttac atcatttgtc gagttcggct
     5941 ggcagcaggc gctgtcctgc ctgttcccgg ccattatttt tgcggcgctt gcactcacgc
     6001 gggtgataga catcccgtac attcccgctt acgacttcat gctccttatc tgtctcgcgg
     6061 ttcaaatcat catgatccgc tccaggctgg aaacgatgga cgagttaaag gtcatttgcg
     6121 tattccatct gatcgggctc gtgcttgaaa tttacaaagt tcacatggga tcatgggctt
     6181 atccgctcga cggatggacc aaagtgttcg gcgtgccgct ctatagcgga tttatgtatg
     6241 cgagcgtcgc cagttactta tgccaggcgt ggcgccggct gcaagtgaag cttcaccggt
     6301 atccgaagcc gtggtgtacc gtgccgctcg gggcggcggt ttacctcaat ttcatgaccc
     6361 accattacat ctacgatttg cgctgggtgt tgaccattct gctgttcgcc gtcttcttcc
     6421 ggacgtatgt cgagtatacg gtgctgggcg tgacgcggcg gatgccgctc gtgctgtcgt
     6481 ttgggttgat cggtttcttt atttgggtag cggaaaatat cgggacgttc ctgggcgctt
     6541 ggcgctatcc gcatcaggcc aacggttgga atctcgttca gttggggaaa ttcagcccat
     6601 ggttcttgct ggtcatcgta tcgttcatga tcgtggccca gttgaagcat gtgaaggaag
     6661 gccgctccca ccgatcccag agcatagaac agccgcttca gatgccataa agacataaag
     6721 agatgtttac taagacacat gacaaacata ttgataaacg ataaatgcag tgatatgcta
     6781 ttgccattca ttttatgcga ggtgctgtat gctgcgaaga aataccgcct ttcttaaact
     6841 ggctatcgcc atgattggga ttacggcttt gattttgtct atattctggc tgcccggatt
     6901 cgtgaccagc cgtgcagcgg agtatccgga ttacatctct ttgaaatatc cggtgctcgt
     6961 cgttgtatat acgacatcga taccttttta cattgctctt tatcaatctt acaagctgct
     7021 ccaatatatc gaacgaaaac atgctttttc cgatctcgct gtagcatcgt ttaagcgcat
     7081 caaacagtgc gccgttgcaa tcgcgatcat ctatgctata ggcggcgcat tccttggctt
     7141 ccagagcgtc ctgctcactt ccatcgcact cataggagca gtcatcattt ttgccgcttt
     7201 cacggtagcg atttttgcgg cagtgcttca agaactgcta acccacgcac ttgccatcaa
     7261 atcagaaaat gatttgacag tctgaggtgt tcatatggcg attatcatca atatcgatgt
     7321 tatgttggca aaacgaaaaa tgagcgtcac cgagctatcg gagaaggtcg gcattacgat
     7381 ggcgaatctg tccatcctga aaaatggcaa agcgaaagcg gtccgctttt ccaccttgga
     7441 gaaaatatgc gaagtgctgg actgtcagcc aggtgatata ttggagtatg tacaagagga
     7501 tccgtcctga acgagaacca gccccgcgct ttcatcaagc cggggcattt ttcattcttc
     7561 cctattgacc cgcacctgct tggcaatcgg cttcgggtca ttccaatgac agatgttgca
     7621 tgcctaaatg gtcctttaga gtcgagcctg tatattctct tctgaacaaa cctcgttcca
     7681 ccaactgcgg catcagcttt tcaaaaaata gctccatcga ttgttccgaa ccgcccggaa
     7741 gcgcgatgaa gccgtcgatt gcgcctgctt caaaccgctc cataatatcg ttcagcacat
     7801 cctcgaccgt tccaaccgca acccagtgag cggacccggt cacctccggc cttgccaaca
     7861 cttctgctac tgtaggctga taggcagtaa tatatcggcg caacagccca gcatgcgttc
     7921 ggctgcggac gggctgattc ggatcgggca tcatatcggc agttacgcgg tgatccagag
     7981 ccaagccgct tacatcaagg cccagcacag attggagcga tgcctgtctg cgctcaacac
     8041 tcaaatgcgc gtgcgcagct tgatataagg catgcgcttc ctcgcgggtc tcgcccaaga
     8101 aaaaatacag tccgggcaga actttgatgg catccggatc gcgtccatgc gcctcggctc
     8161 ttcttcttag atcatgtcgc aactccaccc ccgattccag atccggcatc gccgcaaaaa
     8221 tggcatccgc tatggaagct gcaaaatagc gtcccgtatc cgatgcgcct gcttgaaata
     8281 aaggaatcga gcccgatgga tgggcgggca aagtaagcgg tcccttgaca ctgaaaaact
     8341 cgcctgaatg atggatcggg gacacctgat ccggatccga gaatttgccc gactcgcggt
     8401 caatcacgat ggcttcatgg gggaaacttg cccaaagctt gcgtacaaca tccgtaaact
     8461 cccttgctct cgcatatctt tcttgcgggg aaggcataga cgaatcaccg aaattttccg
     8521 ctccttcaat cgaagtgaca atattccagc cggcacgtcc gttgctaagc cagtgcagcg
     8581 actgaagctg cctcgcgaca atatacggcg gattgaacgt ggtggacacc gtagtaacga
     8641 ggccgatccg ttccgtctcg cgagcgatcg ccgcaaacat catcgtaggg tcgggactgc
     8701 caaaattagc ggaatcgccc agcatctgcg ggctcatata aagataatca gccctgaaca
     8761 gaaaatcgag cttggcctcc tccgccatct tggccacttc gatgtaataa tcaatcgacc
     8821 ccattttctc cacgccgcta tccgaacgcc gccaaccgtg tcctttcatc caggttgccg
     8881 acaaagtaaa tccgatacat aattgccgat gtgcagtcac ttctaccaac ctctcctgtt
     8941 cgataatata gttatcaaca ataatgattc tcattatcag ttaatagtgt agcaaggagc
     9001 ccagcaaaag caaatacaca aatcccaaat gcggcatgaa caattatcta atccggagct
     9061 gaaacacatc catcttcact catagatagg aatattttat tgatctgcgt atgcagaggg
     9121 agacatgccg aatttctttt taaacgctcg gctgaaatat aacgggttgg cgtagccgac
     9181 actgacagca atatcacgga taggaaaaat gtccgcttta agcaattcac tcgctctttc
     9241 catacgataa ttgatgagat agtcgattgg gcgaaccccc gtatatttat gaaaaaagta
     9301 ggagaagctt ttagggctca tagcatgcag ctccgccatc tcttccaatg tcagcgggtt
     9361 catataatgt cttttcatgt attccgtcgc ttcctctatc actcttttac ttggaacgtg
     9421 gctggtcatc cgatgcttgt ggcccaccag cacttgatgc aggatactta aaaataattc
     9481 cttcacgcga agtttcccaa tccctccaag tgtttgagca ttctgatgaa gcatagtcag
     9541 taattcgatc actctcgggt tggctccagg ctccagcttg aaatgagtat tacattcatg
     9601 atcgcggttg tcttccccgc tcatgtccag gcgataaaaa acagaataat attccaactc
     9661 ggattgaccg atcactctcg attccaactg catgcctgga gccgcatgaa ataggattcc
     9721 tggatgtaaa tcgtagaccg ttccattcac acagattcta gcttgtccgc gaactgcaaa
     9781 aagaaatcca tgcctaacgg ttcgaaattc acgcaaaata ctttttggct ggatgaccaa
     9841 acgatagaca tcttctatat tatagggatc attggcaaat accccggcta acctctccac
     9901 atctaccatg atatcgcacc ttccagtggt gtagctgttc tttgacggtc tacaggttcc
     9961 cccgaagagc atcctcctca gggcgggacg gcatagttcg ttattcaaac ttccttcggt
    10021 aatgcgctaa tgcaagtaga ggaaagatat accggtaact atgataatgg atataaaacg
    10081 ctcctcccat cccttggcct ttgggatagt ccgtcgtcca atcctctttc tcaagggaat
    10141 ccagcaaaaa ggtgatacct ttttggatag ccgtcgtcgg ccggtctgca atggctatca
    10201 aggcatccaa cgcccaagcc gtatccgtca gcgtgctcgt ctttaacggg acgtaggtca
    10261 tttgaatatc actacggcac gattcgcccc atccgccgtc cgcattctga atactcctca
    10321 gccatgcggc cgccttttgc atgcttggat ggtttttcgc tacgcccacc gctttcaaac
    10381 cggtaacagc gccccatgta ccgtaaatat aacaaatccc ccagcgcccg taccatgaac
    10441 cgtccttccg ctgatctttt aacagccaat gaacagcatt ccggataacc gaatggctcg
    10501 cgggaaggtt agtatagttc cccaaaaatt caagcgttct cccggtcaaa tccgcacaag
    10561 ggggatccag cagcagaaac cggccctttt caagcggaag aacttctaat accttggaat
    10621 ccgtattttt ttcaaaagct ggccacccgc cattatcgtt ctgcatcggc aaaagccagc
    10681 tgatgcccct tgcccaggtt gttggatgct gtgacgcaat tgtggatatg gaccttaacg
    10741 aggccgtcgt gtcatccaca tccggattca tcgtattcac atcggaaaaa ccccagccgc
    10801 ccggcatgcc gctgggattg tgcacaaccc agtcgccgaa gcggtaatgc tggcggctca
    10861 gcaaatactt gttggccttc gtcaccattg gatcttcatg cgagactccc gctgcctgaa
    10921 gcgtataacc tattaacgag gtattccaca cattggccgt ggtgtattgc atatgaggga
    10981 ggccattaat ttcgcatttc attgcccgaa tcccctcgac ggccttcgta ataatcggat
    11041 cggttttttt atagcctaag gacagcaggg caaaaatcat caaaaaggta ctgctgtaat
    11101 aactataaaa ggttccgtcc tgctccaaat ggtccagcat ataggttcgg gcacgctcaa
    11161 gcgctaagcg gcgcagttcc ctcgggatgc cgatcaatct gttgactccg tcctgaatac
    11221 aggagagcag cgagcgccat tcctttgagc gaccccattg ttcctcatcc tcccttgacc
    11281 atttcaaatc agacaggtcg ggggcatata ctgttttcat cgaaaacttt tgatcagcca
    11341 gtatcataat cggagtcagg ttcgctctcc cgaaaacaga gaaagaatag aaattgatag
    11401 ggaagttgag cgggagcaga atcatttcaa tgggcagagg ggtgaaggac ggccattgaa
    11461 attgcccggt cagtgccagc atgattttcg taaacatgct tacttccgat aaaccgccgt
    11521 gagcgagaat aaactttttg gcggcgcgaa gacgctcgtc ttctttacgg tacaatccgg
    11581 aaaaaagcag tccgtaatag gcttctacag tggaggttac attaccttct ccttcatcat
    11641 aaaaaagctt ccatgctcca ttttgctgct gtttacttaa aattctgcgg caaagccctt
    11701 cgactaattc ctcatcatca atctctaaag tccgtaataa aataatcata taggcatcgg
    11761 tagaaatacc cgtatcaaac ggataagccc atgccccatc gggagattgc tctttgcgaa
    11821 gtgtctcaat aatccaccct atccctgtga cggtatcaat catccccaca ctccttcctc
    11881 ccgcaaaagc tctttaagct atacatattc ggctctgtta tcgagaattc ataagggagg
    11941 gaagctgcca tctttttaat aagaaaacgc cacaaaacgc cgcttgaaac gattcgcgag
    12001 gaattaaaga aaagaaagaa acactcccct gccaccttga atgagctaac tcttagcgag
    12061 aaaaaactat taaataaaat caaaggcatt acacaagacc acaacctaaa taatctgacg
    12121 agaacaaaag cctatctcga gttttatctc cggcatcctg agatccactg ggcattttta
    12181 ggccatatgg tatcgcggaa tggcggctgg aatatgaccg atctcaaggg agaatttcta
    12241 gccacactcc ttgcaaaaga ggagcgggaa tccttttttc attttttaga acgcggcaac
    12301 tggctgattt tccaggatgc atacccgcaa tttttgcttt acgatgagag tttacggcaa
    12361 aatagaccca tgttttatct gctgcctcat ttaaatgttt ctatttttat ggaaacggtt
    12421 tggaattatt tttggagagt ccgagatacg tatattcttt gtatagcgtt agtcatcaat
    12481 gaacagagct atttggaaca aagggtcatc caaaaccccc attatcaaaa agaagtatta
    12541 cacaagatcg aatttcacct tcagaactgg ctatccttta atcaaattct gtttccttcg
    12601 gaaggcgaga acgtaaaggg gcagaccctt caccaatttc agtcactcca tgagcgaatt
    12661 ttacttggaa aaaggctgta tgcgattttg tttaaaaata aggattttca taggcaggct
    12721 ctggattggg cgacacgtca gccgcatacc ggatcgagga aagactactg gccgcattta
    12781 tttaatgatg taaatgaagg cacaccggga attacctatc ccttacggtt taaatcgtgc
    12841 cggcttcgca aaggagcaag gagaatttac agccccaagc tggaatatgc ctggaaaaat
    12901 gtcagccagc cggaagcgga accgggggat tggtttcaac atataagcgt ggtggattat
    12961 ttggaggatg accaagaaat gacggacgga gagattaaga atgactactg caacacattg
    13021 gagcggctcg aaattgccgc gctcgccaaa aaaacgattc actttttgga acaaagatag
    13081 tttagcatgt gcagtactgg gatcgttgct tggtacgtat ttagatctct attttgtcgg
    13141 aaaagggctg tatcattttc cttaccggct gctaccggag atcttttcga ttcatatcgt
    13201 cttcacttta atcgggttgc ctatattgac gatgattttt ctgtactgca tctcccaagc
    13261 aaatcgttgg ggaagggtag ggattatcat ctgtgtcagc ctgctgatgc cgatttttga
    13321 aaaaatagcg gagcgattag gggtgtttgt ccattccgat aaatggatgc atttatacag
    13381 cttcttcggt tatttactgt ttttcacgat aatttcaggg gtttattttt ggctgagaaa
    13441 aaaaagtggt taaaaacaaa acttgaacct ccatagtttc cctcacgatt ttgagccgca
    13501 gggctcattc tcccccttct acgtagactg gagaagccac gaataattta ttcacattgt
    13561 gtaattctat aagtacacga tttccaaaga aatggaggaa agatgatctt gcgtttattg
    13621 ttattcgttc tagcaatgct tagtgtgctg tcgggatgtg ctcagaatca agcgcaacaa
    13681 aagcccggca gcaatcctta cagctccagc gctccccaac caccgcaaat tttgcaaaat
    13741 tccgttagat cttcaacacc agatcttgca gatggacctg agggaaattt gcgtgagccg
    13801 catgcccttt ccttggcgga tttgcgggcg aagtacccat caacgtttat actgcacggt
    13861 cccggtacga aacgggaaat tgccctttca tttgatgatg cgccagatga caactttaca
    13921 ccgaaggtgt tggatgtact caaaagcgaa ggcgtgaaag caactttttt cgtagttgga
    13981 aacagaatcg agaagcatcc cgacatcgtg aaacggatcg tcgaggaagg ccatatcctt
    14041 ggtaatcatt cttacaacca tgcaaatttg cctaaattaa gcgatgcaga atttcgcgat
    14101 caaattatga aaacggatca attgattcgc gagcataccg gatatacccc caatatcgtc
    14161 cggccgcctt atggtaatat cagcgagaat caaatcaagt ggttggcaag ccagaagaaa
    14221 aaggtcacca actggaacgt cgattccctc gattggaaag gattggatgc agaagaagtg
    14281 aagacaaatg tccttgctca tgtatcccca ggggcaatta ttttgcaaca ttctgccggg
    14341 ggaacaggcc aagatttatc cggaacggtt ttggctttgc cggacatcat tcgtacactg
    14401 aaaaacgatg gggtgaagtt ggtgaccatc cccgaattgc tggatctgaa cgtcaaataa
    14461 aaggcttacc gaagaggata cgtcatgaac aatgaacata tcgtgtcttc ttaaaaaata
    14521 aaaagtcctt taggattttt taaccccaaa ggacctcatc gcttttgctg gtgccggtga
    14581 gaggactcga acctccacgg tttccctcac gattttgagt cgcgcgcgtc tgccattccg
    14641 ccacaccggc ctataaagtt aatctggcgc gccctgagag attcgaactc ccgacctttt
    14701 gattcgtagt caaacgctct atccggctga gctaagggcg cattcttctg gagcggacaa
    14761 cgggattcga acccgcgacc ctcgccttgg caaggcgata ctctaccact gagctatgtc
    14821 cgcgcatggg caagtccagc ctgtccatcg tcattccctc gcttgccgcg agagcatgct
    14881 tcaagaagga catttattaa tataacagac cacctagcga aaatcaattc ttttttgatg
    14941 aaaagtgatg ttttttcctt agctttctct tcttcaatat gagagcaaga atggaaaaaa
    15001 ccgccttgtc ttcagggtaa cccttcggac aagacggtat atacttatac tttcttctta
    15061 tttcttaacc cacttcaatt cgaacttcgc ttcccgcatg ccgacgaccc ggccattgtc
    15121 attcttcgtc tctggcggac tgagctgccg cagacgctcg atcgtctcca cgttcgaata
    15181 ttcaatctcc ttcaaaatat gggctgcgat gagcggccat tgatcctcgg agccgtccat
    15241 cactttgaag gcgatcccca tgcgctcttt ccgcaagccg aagcagtaga ttcctttggc
    15301 gccgcctttg gcgacgatgt tgtcgtcctg cagaagcgtc ggacagatca actgcgtgcc
    15361 ggatacgtag aacgggtacc ggttcattag cgtcgtcaag cggatgacag ccgctcggat
    15421 cgcctcatcc ggaatcagat ccggacaagc aagccgcaag tacagcgtag cgatattgcg
    15481 gatcggcagc gcatagaccg ggaagccgca tccgtccgtc cctaaccgga tctgctcgac
    15541 aggcacatcc gagagcgcgg acatcagaga cagcacctgc tgctgcaccg ggtggttctg
    15601 ctcggcatag ttctcggtcg gccagccttt cattttgcag agcgccagca ccccgagatg
    15661 cttgcccgag caattgtgat agatggagcg tgcaggcttg ccatgggcga tcagctcgtc
    15721 gcgggccgct ccgttcagcg gatacgtcgg cttgcatacg aactgcgact ccgagattcc
    15781 ggtcttgcgc atgaacgatt ccagcgcttc tacatggaat tgctgtgccc ggtgcgatgc
    15841 cgtcatgagc acgatctcct cgtcgctcaa tccataatgc tccggcactc cggccatgag
    15901 cgcgggcaac gcctgaaccg gtttcgatga tgaacgcatg aagctgacat agttctcatc
    15961 ccctaccgag aaaagcggct ctccctgctc attcacaccg accatatggc cggtgtacgc
    16021 gcattccaac caattgccac gatactcttc tactaacact ttacccaagt ctaccacgtt
    16081 ggttcctcct cgcaaactcc gggatgactg tcctgctgct actcattata ctctacgacg
    16141 accatttggt ggcattccaa atgaggcacg gtaaattgca catctccccc ggacgccttg
    16201 aacccgattt cggtcatttg cggagccaga tagacccgct tcacgccggt caccggcagc
    16261 tggagctgaa cctcgacctg ttgcagagga atcatatctt caatgatttc gacccgttcc
    16321 ccgcgcttca ccggggaagc atacagcaaa tgattgatat agcggcgctc tgctgcctga
    16381 tgctggagcg tcgtcacgcc ctgggcaggc agcgtcgtct tcaacgtgat ctgctccccg
    16441 agcagccggc gaagcgcgaa cagaaccatt tccttcaaaa tgagactgcc cttcgtcgca
    16501 taatcttcaa atacgttcca agcgatataa atgccttggg cggattcgac catgcctgga
    16561 ccgccatcct gttcagaact cggcgcatgc tgatgggaac agaaacggaa ggcctggcgg
    16621 ttgaagtacg gatcctctct tcttccaagc tcaatcccgt ctgtcagctc gatgcggcgc
    16681 ccttctccgt acatgacata agccgcttct ccgagattcg ccatgccatc gcagagcgga
    16741 cggaaataat ccggacggaa cggattcagt ccgctatcgg tgaagccaag gggcagcatc
    16801 tgccgcgtca gttcgacatt caggccggaa cgcccggacg ccagcacttt gccccctgca
    16861 gccaagaacg cctccacctt cggcaaaatg gtatccttca tcacgatcga gtccgggaga
    16921 atgagcacct tatagccgct ccagtcgctt tccatgtcta cgatatcgaa caagattttg
    16981 ccttccagca gcatgcggac cgcacccata tcgactttgc cggaatacat ggctccgctt
    17041 tcctgctgca cgccggcggc ctctaccgta agcagcgcga catccgcatg gttgactgcg
    17101 ttgacgcacc aggcttcctt ggcctccact tccgcgtacg ccttcccaat cagctcatac
    17161 gtcgcccggt ccatctgtcc gccagggtga agctggtctc cgatcgagca gcgggcaccg
    17221 ttcgccaagc tcagcgcagt ctcatagcgc aaggcgttcg gatgcttgta accgccgaat
    17281 tcgccccaga aggtatggaa tttcccggtc atgccgagga aatggaagcc ggttggctgc
    17341 gcgtagcggg cagacagcgg gaaatgatca tacccccagc cgccggtcgg cagcgactcc
    17401 agttcaagat gggagttcat ccccatcaga tcgcggcgcc cctgatgaat atgtcccgcg
    17461 ttatggaaga ccggcaatcc cggcttgatc gcgtcgatcg cttcccgaat gcgtgtcgtg
    17521 tagttcgcgt aaatgcggcg gccgttcgca atcacatctt ccttgttatg cggatcgagg
    17581 ccatccgcct gcatttgctt cagacaggtc gtacaatagc acgtccgctc gcctacaata
    17641 tcgaggaata tgccgtcgcc gtcatacttc cgcaccacct cctgcacctg cttaatgacc
    17701 agttcaagat agggcgtatt caagcaaaat tgatgatagc ccggcttcat gaaggagtcg
    17761 acccagttca tccggtccgc ttcatcccgc atcaaccatt gcggcttctc ccaagccagc
    17821 ttctcatcga agccgacgga tatataaatt ggcaccttga cgccgatctc gtgcgccgct
    17881 tcgatctggg cgccaagcag gtcaaaatca agccccggat ggatttcatt cgttgccgaa
    17941 gggaagtacg cccagccatg atggcacttg gcgaacacgg ttatcgagtc cacatgtccc
    18001 agctgcagca tttcttgaaa attcttttta gaaaaatttc tcccgatatc agaaatatgc
    18061 tccgacgtat ggaaatcgag gtgaacctgt ctgtagcgca taatatcctc ctatacatga
    18121 cattttcttg agatcattgt atcatttacg taggcggacg tatttaagac agcttcctgt
    18181 catttgtaca aaattccgat catgtggagg aaaaacgatg aaactgctca gtgaggtaca
    18241 gccccatatc cgtgcggccc atatgtacaa ctatcgcggg gctcccgagg agcagcggcg
    18301 cagaggctac agctatgcct tccatctctt cacggaaggc catggacata tgattgtcaa
    18361 tgaacaggtc taccccgttg ccagtggcag cctgttcttc gtccgtccgg gagagggaca
    18421 ctatttcgtt ccggccccgg gggaaacgat ggatgcctgc aatatttact gcgacttatg
    18481 gtgcctgccc cagcccaagc agccaacctt cgcttatcaa tgggacgact atgatccccg
    18541 gtgccttacg gaacagatgc cctgccccga gttggatgcg ctgcctacga gcatgtcgct
    18601 acggccttac ccgcatttga tcgagctgat caagcagacg ctggctgcgt tcaaccgttc
    18661 tggcaaatat acggcacaag cggtttccgc ctgcttttat tcctggatat tgcaatggca
    18721 tgaagcaggc agcctgaccg agacggccga ttaccggatt acccgcatat tggagcagat
    18781 ggaggcctgt ccggagcagc ggttctccgt agattactgg tgcagcgagt gcggattgga
    18841 gaagtcgcaa ttctatcggc tgttcaagca ggagaccgga atgtcgccca aagcgtacgc
    18901 gctgcaggcc cgcatgaaaa aagcggccgt cctgttgatg gaaagccgcc aatcaattac
    18961 ggacatcgcg cttatgctcg gatacgattc cattcattat ttctccaacc aattctcctc
    19021 cgtgtacgga gtcagcccct catcctaccg gatgggcaaa gaataccaga agcttgatcg
    19081 ctggtcataa cgatgctcgg gccagcttgt gcttgcaagc aagctaaggc tggcccgatt
    19141 ggcgacccca ttcatccaac cattgaatgg cggcaaggcg ttcaccccaa gtattttgca
    19201 gaagccggga tagacgctga aattggccgt tgaccgcgct gcgggcggcc gcccatgctt
    19261 ccaccggcaa gcggaacaaa gagccgatca atgtccgttc cgctgccgcc agcggacgca
    19321 ccagctcata cccctgtaac agcgctccca tcaacagcgg attgaaattc gtggtattca
    19381 aaagcgtctt tgcgatttcg tagtaggttg agtccattct gacctgatcc caatcaatta
    19441 aatatatgcc gttcgagtgc ataatgacat tcgggaaggt gacatccccg tggattaatg
    19501 ccgggaagcg gatttcatcc cggagcacct gctgcgtgac cggcctctgg atagacctcc
    19561 acgcctcctc agccaagcga atgcactgat tgccatgttc cctgaaccaa gccgcggtgc
    19621 ccttccgctt acgcatcatc gtcaatcggc gtcggaacag gcggtcctga tcttggaaaa
    19681 atgaaatctg acgggaagtg tatggagaca tggggggaag atctgcctgg catatcgtat
    19741 gaagcgtggc cagcgcccgg ccgagttgct catagtggta tccttgttgg agattgccgc
    19801 cttctaccca ctctatcatg tagtacggcc ggccagattg atacacccaa taacggccgg
    19861 atgcggtgac cagccaatgg ggcagatggg gataatgctt tgccttcagc ttatgaatat
    19921 aagccgtgac gctaacaatt tgctgcttcg ttgtcaaatt cgtgtttttt ctccggtaaa
    19981 atggcttgat gacatagacg ccttcatccg taatcgcccg aaatgccgca ttgcgtctat
    20041 acagcgaatg gcagggctga atgtgacgca agtgcagccc gtatcgccgg acaaacggtc
    20101 taagccgtgc tgtactgatt cgccttgcca agccgtcatc ctccattctt ttccctgcac
    20161 atggttacaa tgtattcgta gaatggttca cggtcacttc ttagcagccg aaaaaggaaa
    20221 aaagcctgcg catctgcgca agcttgttga atgcatactg gtgagccatg aaggactcga
    20281 accttcgaca ccctgattaa aagtcaggtg ctctaccaac tgagctaatg gctcgtatgg
    20341 tgacccgtac gggattcgaa cccgtgttac cgccgtgaaa gggcggtgtc ttaaccgctt
    20401 gaccaacggg ccccagcatt tcataataat ggcggagctg acgggattcg aacccgcgtt
    20461 ctcctgcgtg acaggcaggc atgttaggcc tctacaccac agctccatag ttgttattca
    20521 ttttccgcat cgatgcgtaa taaccgctct cgatggaaat aatattgcgg ggacaggatt
    20581 tgaacctgcg accttcgggt tatgagcccg acgagctacc gaactgctcc accccgcgat
    20641 aatatggtgg acactaacgg gttcgaaccg ctgaccccca ccctgtcaag atggtgctct
    20701 cccaactgag ctaagtgtcc atatgaatgt aatggtgacc cgtacgggat tcgaacccgt
    20761 gttaccgccg tgaaagggcg gtgtcttaac cgcttgacca acgggccacg ctggcggaga
    20821 gagagggatt tgaaccctcg agacgcttgt gacgcctaca cgatttccaa tcgtgctcct
    20881 tcggccagct cggacatctc tccgtgtggc tccccgaaca ggactcgaac ctgtgacaac
    20941 tcggttaaca gccgagtgct ctaccgactg agctatcagg gaatgtaacg tatctctcgg
    21001 acttcgccgg agaccgatat gtaaagcctc tgcttggcag cgtcctactc tcccaggacc
    21061 ctgcggtcca agtaccatcg gcgctggagg gcttaacggt cgtgttcggg atgggtacgc
    21121 gtggaacccc tccgccatcg ccaccaaaca gataaggtat tgtaccttaa aaactgaatg
    21181 cgaaagttcg tcttgcgaat catcttagtt aggataagcc ctcgaccgat tagtattggt
    21241 cagctccatg cattgctgca cttccacctc caacctatct acctcgtcgt cttcaagggg
    21301 tcttaccaat gtgggaaatc tcatcttgag gggggcttca cgcttagatg ctttcagcgc
    21361 ttatcccttc cgtacttggc tacccagcta tgcctctggc gagacaactg gtacaccagc
    21421 ggtacgtcca tcccggtcct ctcgtactaa ggacagctcc tctcaaattt cctacgcccg
    21481 cgacagatag ggaccgaact gtctcacgac gttctgaacc cagctcgcgt accgctttaa
    21541 tgggcgaaca gcccaaccct tgggacctac ttcagcccca ggatgcgatg agccgacatc
    21601 gaggtgccaa acctccccgt cgatgtggac tcttggggga gataagcctg ttatccccag
    21661 ggtagctttt atccgttgag cgatggccct tccatgcggt accaccggat cactaagccc
    21721 gactttcgtc cctgctcgac ttgtaggtct cgcagtcaag ctcccttctg cctttgcact
    21781 cttcgaatga tttccaacca ttctgaggga accttggggc gcctccgtta ctctttagga
    21841 ggcgaccgcc ccagtcaaac tgc
//
