LOCUS       NZ_JAQQGI010000014     22898 bp    DNA     linear   CON 12-MAY-2024
DEFINITION  Stenotrophomonas geniculata strain BLCC-B124
            NODE_14_length_104860_cov_211.687363, whole genome shotgun sequence.
ACCESSION   NZ_JAQQGI010000014
VERSION     NZ_JAQQGI010000014.1
KEYWORDS    WGS; RefSeq.
SOURCE      Stenotrophomonas geniculata
  ORGANISM  Stenotrophomonas geniculata
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas.
REFERENCE   1  (bases 1 to 104860)
  AUTHORS   Lefler,F.W., Fernando,B., Fernando,A., Berthold,D.E., Kennedy,A.,
            Indest,K.J. and Laughinghouse,H.D. IV.
  TITLE     Draft genome sequences of cyanocidal bacteria isolated from
            cyanobacterial infested fresh waters
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 104860)
  AUTHORS   Lefler,F.W., Fernando,B., Fernando,A., Berthold,D.E., Kennedy,A.,
            Indest,K.J. and Laughinghouse,H.D. IV.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-FEB-2023) IFAS, University of Florida, 3205 College
            Ave, Davie, FL 33314, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-JAN-2023
            Assembly Method                   :: SPAdes v. 3.15.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 431x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028550615.1-RS_2024_05_12
            Annotation Date                   :: 05/12/2024 16:37:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,164
            CDSs (total)                      :: 4,091
            Genes (coding)                    :: 4,068
            CDSs (with protein)               :: 4,068
            Genes (RNA)                       :: 73
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 65
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 23
            CDSs (without protein)            :: 23
            Pseudo Genes (ambiguous residues) :: 0 of 23
            Pseudo Genes (frameshifted)       :: 2 of 23
            Pseudo Genes (incomplete)         :: 19 of 23
            Pseudo Genes (internal stop)      :: 4 of 23
            Pseudo Genes (multiple problems)  :: 1 of 23
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:51:48
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7075
            Orig. end                         :: 29973
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAQQGI010000014.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22898
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22898
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22898
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12898](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12898
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(709..1032)
                     /gene="fdxA"
                     /locus_tag="PQS91_RS16875"
                     /old_locus_tag="PQS91_16870"
     CDS             complement(709..1032)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /function="Ferredoxin"
                     /gene="fdxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005994928.1"
                     /locus_tag="PQS91_RS16875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16870"
                     /product="ferredoxin FdxA"
                     /protein_id="WP_004153066.1"
                     /transl_table=11
                     /translation="MPFVVTENCIKCKHTDCVEVCPVDCFHEGPNFLVIDPDECIDCTL
                     CEPECPVNAIFPEDDVPAGQESFVALNAELAKEWPVLTVRKDPPADAGEWDGKPDKLKL
                     LER"
     gene            1225..2649
                     /locus_tag="PQS91_RS16880"
                     /old_locus_tag="PQS91_16875"
     CDS             1225..2649
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019661180.1"
                     /locus_tag="PQS91_RS16880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16875"
                     /product="sugar porter family MFS transporter"
                     /protein_id="WP_043403359.1"
                     /transl_table=11
                     /translation="MSPAQPNIASHGGENTAFIVLISCVATLGGFLFGFDSGVINGTVD
                     GLRQAFNSSEAALGFEVASMLLGCAIGAFLAGWLGDRLGRRGVLIASALMFLVSALGAG
                     AAHASWLFIAARVLGGFAVGAASVMSPAYIAEVASARYRGRLATVQQMAIICGLFAAFL
                     SNYLLARAAGASTEPLWLGHEAWRWMFWMQALPSGLFLLLLLVIPESPRFLVVKGRQQQ
                     ARAVLSRLYGEVAAAAKQAEIEASLAQDQHKPRFADLRDTVSGKLRPILWVGIGLAMFQ
                     QLVGINVVFYYGAVLWQAVGFSESDALLINVLSGALSIGACLLTVLLIDRIGRKPLLWI
                     GSVGMSVALVLMVVAFASGSLADGRLQLSDGMGRLALVAANVYVVFFNMSWGPVMWVML
                     GEMFPNQIRGPALAVAGAAQWTSNFAITVTFPMLLAGIGLAGAYGIYTVAAILSIVFVV
                     RYVRETKGKELEQMEG"
     tRNA            complement(3177..3251)
                     /anticodon=(pos:complement(10291..10293),aa:Glu,seq:ctc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="PQS91_RS16885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="PQS91_16880"
                     /product="tRNA-Glu"
     gene            complement(3177..3251)
                     /locus_tag="PQS91_RS16885"
                     /old_locus_tag="PQS91_16880"
     misc_feature    3195..3210
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.79"
                     /tool="antismash"
     gene            3304..4677
                     /gene="pcnB"
                     /locus_tag="PQS91_RS16890"
                     /old_locus_tag="PQS91_16885"
     CDS             3304..4677
                     /EC_number="2.7.7.19"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:1990817 - poly(A) RNA polymerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006378 - mRNA polyadenylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pcnB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017116093.1"
                     /locus_tag="PQS91_RS16890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16885"
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="WP_029550838.1"
                     /transl_table=11
                     /translation="MGNPETSTGSANIISSATSPFSLRVIPRDQHTISRKDISPNALRV
                     LYRLRDAGFGAYLVGGAVRDLLVNGQPKDFDVATDATPEQVKQLFRNCRLIGRRFRLAH
                     VVFGREIIEVATFRANSDDGSGDREMENGMLVRDNVYGTIEDDAIRRDFTCNALYYAIE
                     DFSVRDYTGGFEDVQARLMKLIGDPEQRYREDPVRMLRAVRLAAKLGFQIEEGTAAPIP
                     HLAGLLNEAAPARLFEEVLKLFLSGHGVASFEGLERYGLLDVLFPESAKALKSNRTGAL
                     RRMLVEGLANTDARVANDEPVSPAFLFALLLWPAFCRAQATLLKQGVAPEEAQRRAADR
                     VTVQQLSTIALPRRFSLPMQEIWLLQSRFSSRQRKRVFRTLTHPRFRAAFDFLSLRQVA
                     SSEHAVDVEFWREAQAQSGRELESSLDAMHSEDGDDESGAPRKRRRRRRRPGAAAAGE"
     gene            4681..5166
                     /gene="folK"
                     /locus_tag="PQS91_RS16895"
                     /old_locus_tag="PQS91_16890"
     CDS             4681..5166
                     /EC_number="2.7.6.3"
                     /GO_function="GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA]"
                     /GO_process="GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="folK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019338321.1"
                     /locus_tag="PQS91_RS16895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16890"
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="WP_019338321.1"
                     /transl_table=11
                     /translation="MTLAWIGLGANLGDAAATVGAAIAALDGLPGTRLRQASRLYATPA
                     WGNEDQPPFVNAVASVETTLPADELLQAMLALERGFGRVRDPAVHWGPRALDLDLLLYG
                     AQVLDHPGLQVPHPYMHERAFVLVPLAEIAPDLAIPGHGRVQDAVMRVDACGIAPIG"
     gene            5201..6016
                     /gene="panB"
                     /locus_tag="PQS91_RS16900"
                     /old_locus_tag="PQS91_16895"
     CDS             5201..6016
                     /EC_number="2.1.2.11"
                     /GO_function="GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005416119.1"
                     /locus_tag="PQS91_RS16900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16895"
                     /product="3-methyl-2-oxobutanoate hydroxymethyltransferase"
                     /protein_id="WP_019338322.1"
                     /transl_table=11
                     /translation="MSTHADSKPWTVPALAEAKRNGQKLVMLTAYDAGFARTFDANGVD
                     LILIGDSLGMVVQGHDSTLPVTVADMVYHTRAVARVLQRALLVADLPFGADATPERALD
                     ASLQLLQAGAEMVKIEGAGFKVDIIRYLVEREIPVCSHLGLTPQSVLRLGGFKIQGRGD
                     AARQLVEDARAVAAAGASIMVLECVPTPVAAEVTAAVDVPTIGIGAGPQCDGQVLVLHD
                     FLGLDSGHRRPKFVKDFLAEGGSVAGATRAYADAVRDGSFPDEQHAYAQ"
     gene            6013..6852
                     /gene="panC"
                     /locus_tag="PQS91_RS16905"
                     /old_locus_tag="PQS91_16900"
     CDS             6013..6852
                     /EC_number="6.3.2.1"
                     /GO_function="GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011259031.1"
                     /locus_tag="PQS91_RS16905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16900"
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="WP_272774453.1"
                     /transl_table=11
                     /translation="MIQTFNELGALREQIAQWKREGLRVALVPTMGNLHGGHHSLVTLA
                     RQYADKVVTSIFVNPTQFGPNEDFSRYPRTPEADVAGLEQAGCDAVWLPSVEAMYPLGV
                     DKTTQMHAPGVSEVLEGASRPGHFDGVCTVVARLFLQVQPDVAVFGRKDYQQLAVIKQM
                     VAELSFPIQIVGADIVRDEDGLAKSSRNQYLSAEQRPVATSIHRTLLGMREGYVAGHTR
                     AQIEADATAALQAAGFQVDYAVLRTPELAEPTFDGGGRVALIAARLGTTRLIDNLEF"
     misc_feature    6915..6926
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            6919..7416
                     /locus_tag="PQS91_RS16910"
                     /old_locus_tag="PQS91_16905"
     CDS             6919..7416
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010484309.1"
                     /locus_tag="PQS91_RS16910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16905"
                     /product="hypothetical protein"
                     /protein_id="WP_197579420.1"
                     /transl_table=11
                     /translation="MKAPSTDTGRLAQASILAVLAAGMLPAQLFGGLLFALEFRRTPMP
                     ALTGGGLMFVLAVCNAIAVLLPMALILQSQQRLRRAGFVLVGFGLGALAMATCAWPGEN
                     QGPWLQRLRYVDTFDVISYALQVLAAGGFGLVAGLAFHTVFRLSLEGGSGHAAPPPPGE
                     GT"
     gene            7504..7884
                     /gene="panD"
                     /locus_tag="PQS91_RS16915"
                     /old_locus_tag="PQS91_16910"
     CDS             7504..7884
                     /EC_number="4.1.1.11"
                     /GO_function="GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011036943.1"
                     /locus_tag="PQS91_RS16915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16910"
                     /product="aspartate 1-decarboxylase"
                     /protein_id="WP_005409061.1"
                     /transl_table=11
                     /translation="MHLSLLKTKIHRATVTHSELNYEGSIAIDDNLLAATGIREFEQVH
                     IWDVTNGARFSTYAIRAEAGSGVVSLNGGAARHVQVGDIIIIAAFASMTEQEADSFKPK
                     LVYVDGKNQITHTNDTIPTQAA"
     gene            7881..9395
                     /gene="pgi"
                     /locus_tag="PQS91_RS16920"
                     /old_locus_tag="PQS91_16915"
     CDS             7881..9395
                     /EC_number="5.3.1.9"
                     /GO_function="GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pgi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019300464.1"
                     /locus_tag="PQS91_RS16920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16915"
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="WP_224329204.1"
                     /transl_table=11
                     /translation="MTTNNGFDSLHSHAQRLKGASIPSLLAAEPGRVQDLALRVGPLYV
                     NFARQKYDAAALQALLALAAERDVGGAITRLFRGEQVNLTEGRAALHTALRGDVVDAPV
                     AAEAYATARTIRQRMGVLVRALEDSGVTDVVSVGIGGSDLGPRLVADALRPVSGARLRV
                     HFVSNVDGAAMQRTLATLDPARTAGILISKTFGTQETLLNGQILHDWLGGSERLYAVSA
                     NPERAAKAFAIAADRVLPMWDWVGGRYSLWSAVGFPIALAIGFERFEQLLEGAAQMDAH
                     ALDAPLERNLPVLHGLTDIWNRNLLGHATHAVMTYDQRLALLPAYLQQLVMESLGKRVQ
                     RDGQPVTTDTVPVWWGGAGTDVQHSFFQALHQGTSIVPADFIGCVHSDDPYTINHQALL
                     ANLLAQTEALANGQSSDDPHRDYPGGRPSTLILLDALTPQALGALIAMYEHAVYVQSVI
                     WNINAFDQFGVELGKQLASGLLPALQGEDVAVADPMTREILAQLKG"
     misc_feature    9705..9723
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: medium, score: 27.95"
                     /tool="antismash"
     gene            9712..9918
                     /locus_tag="PQS91_RS16925"
                     /old_locus_tag="PQS91_16920"
     CDS             9712..9918
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268305.1"
                     /locus_tag="PQS91_RS16925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16920"
                     /product="DUF6229 family protein"
                     /protein_id="WP_010484314.1"
                     /transl_table=11
                     /translation="MDLNDDVVSGWLNGSDDVDGCANPAGSLFIYGAAATEAALTGASD
                     TMITGGTNECTTTVSVINHCLCC"
     CDS_motif       9712..9864
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MDLNDDVVSGWLNGSDDVDGCANPAGSLFIYGAAATEAALTGASDTMITGG"
                     /locus_tag="PQS91_RS16925_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9865..9918
                     /prepeptide="core"
                     /locus_tag="PQS91_RS16925_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.40"
                     /molecular_weight="1751.0"
                     /monoisotopic_mass="1749.8"
                     /core_sequence="TNECTTTVSVINHCLCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDLNDDVVSGWLNGSDDVDGCANPAGSLFIYGAAATEAALT
                     GASDTMITGG"
                     /leader_location="[9711:9864](+)"
                     /alternative_weights="1769.0"
     gene            10001..12898
                     /locus_tag="PQS91_RS16930"
                     /old_locus_tag="PQS91_16925"
     CDS             10001..12898
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019338325.1"
                     /locus_tag="PQS91_RS16930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16925"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_272774455.1"
                     /sec_met_domain="DUF4135 (E-value: 5.3e-80, bitscore:
                     262.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.7e-35, bitscore:
                     114.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASPAAAAFARITEHFLAHARAALATGLHDPAIALQPGERELLH
                     AHGDAALREHAQLKLNRVLLLELHAAARSGDIGPLGSAGALDEFVALATSEGFRTHLQR
                     RYPVLLPRLTRMLEGQCAAVVELAVRIGSDRAALAGLLGAPAGTLHAVALGRGDLHGGG
                     RTVARLQFEGGTVMYKPRSLRIDATLDGLLCTLFGDGPDRVCVPKVIDRGSHGWAAFAA
                     HRYCADDVELRAYYRGLGHWLAILRLVGGTDIHLENLIAVGPVPVVIDAESVFSRVIEI
                     EPSGLGDAYDTAVKLMRNSVLRTGIVPFRTAGLGMEGVDLSAAGALPGEQPRVQVPVIV
                     EGGTEPARLGMVEAEVSVAQNHPSAQPDVSLYWDHISEGFIDASGRLRALDAKGELMPL
                     LAAFEGCQVRDVRRPTMAYAELGRMLWHPASLHNEAQAVERAIDLLVRNAAVSPAAPSD
                     LDTVRSEVDDLRHGDIPIFTSQLDAARIRSIADNWRAMRIDLEDVTIRSTLVATDLNQH
                     ALARAEARSGYSYAAQHPRADDLDARRRTLAARAVESLLRLAVHGEDGSMTWITPEVTR
                     TGWTVQPVQPDLYFGLGGIAFALAAYHREVEQGRADPVAGLGPAIDGALAVFQTMCEQH
                     PAEIDGGFVGTGSQIWTLLALHDLLQRPALLVLAERCAEAAERRGFQEATKFELIDGVS
                     GMILPLLSLAAATGNARWLELAAAAGRRMQEAAIVDADGARWPTPQFREPIGGFGHGAM
                     GMGWALARLARSDAGSVPERAAWRQLAEGAFAFQAALFEPYTGHWRDIHLQDGQKNFPT
                     WCHGSVGIGLAAADLYARTGDPAQLRDMRRAVADARGKWGFSHTLCHGDVSTRELLVLA
                     AALDPEGCPYPQDEAAIEIVSSIEEHQGMVGGLTRAAFTPGLMIGLAGAIYGFLRMHPA
                     CALPSPLLQETTVARVDAPASRSSTAQDRAVLAEV"
     gene            complement(12920..13489)
                     /locus_tag="PQS91_RS16935"
                     /old_locus_tag="PQS91_16930"
     CDS             complement(12920..13489)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012510702.1"
                     /locus_tag="PQS91_RS16935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16930"
                     /product="response regulator transcription factor"
                     /protein_id="WP_012510702.1"
                     /transl_table=11
                     /translation="MSLHHSTLGLLVDDDELYLRTLQRSLARKGLETQTAQDAASALAL
                     ARQHPPAFALIDLKLGSDSGLALIQPLRALRADMRILLVTGYASIATAVEAIKLGADDY
                     LPKPATVPMILRALGEEDDGPADDGEMEVPDAMTPISRLQWEHIQQAMHETGGNVSAAA
                     RLLGMHRRSLQRKLAKRPSPERDPSR"
     gene            complement(13486..14712)
                     /locus_tag="PQS91_RS16940"
                     /old_locus_tag="PQS91_16935"
     CDS             complement(13486..14712)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019661188.1"
                     /locus_tag="PQS91_RS16940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16935"
                     /product="ATP-binding protein"
                     /protein_id="WP_032128856.1"
                     /transl_table=11
                     /translation="MTGPDAPFLRTLCSLRWLAVGGQAATILVATWVLGLPLPQLPLWA
                     GVAVLTLFNIYTQLRPEAADTAPLTAFGHILVDVIILTWMVGWSGGMANPFSSLFLILI
                     ALAAFALPLRWALAVALACLLGYAASGIFGQSLPDGYFRAQDLNRWGVVANFLISAAVV
                     LTFSTRLALALRQRELELSALRERFARNEGIVALATHAASVAHELNTPLATMTLLADDV
                     AERSEEPEVREDMETLRELLVQCRERVLALAAPASADAPGRSHSSAQQVLEQWRLVRPT
                     IDLHRNDDAPLRLPLDPGVGHLLMVLLNNAADAGEQAGRPRVDLDLRIEGDDLIGEVRD
                     YGHGFDARAAVLPGKLFGSSKSEGMGVGLALSHATIERLDGEMWMRPAQGAGSRVGFRL
                     PLTPREDTP"
     misc_feature    14782..14800
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.46"
                     /tool="antismash"
     gene            14827..16092
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="PQS91_RS16945"
                     /old_locus_tag="PQS91_16940"
     CDS             14827..16092
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019300453.1"
                     /locus_tag="PQS91_RS16945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16940"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_014036794.1"
                     /transl_table=11
                     /translation="MHDAVTRPTPPSDATSWPRRQTHAVQIGGVTVGGGKPVVVQSMTN
                     TDTSDVASSVKQVAELWRAGSEMVRLTVNTVEAAAAIPRIVDKLAMMGIDVPLIGDFHY
                     NGHQLLTAEPACAEALAKYRINPGNVGFGKKKDLQFAQLIEFAIRYNKPVRIGANWGSL
                     DQALAAKLMDENNLREQPWDAGRVLREALIRSALDSAEQAVELGLPRDRIVLSAKVSGV
                     QELIAVYRDLAQRSDFALHLGLTEAGIGSKGIVASSAALSVLLQEGIGDTIRISLTPEP
                     GQSRTQEVIVAQELLQTTGQRAFTPLVTACPGCGRTTSEFFQELAKVVQNHVREKMPLW
                     KIHHPGAENMTLAVMGCIVNGPGESRHANIGISLPGTGETPAAPVFVDGEKKVTLRGDN
                     IAQEFVALIDDYVEHKYVRSAG"
     gene            16073..16822
                     /locus_tag="PQS91_RS16950"
                     /old_locus_tag="PQS91_16945"
     CDS             16073..16822
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646755.1"
                     /locus_tag="PQS91_RS16950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16945"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_010484323.1"
                     /transl_table=11
                     /translation="MSEAPDKPAILAAPESASGFRHWMARNAWRLVLLFGGVLLPLAGF
                     VALADEVHEFESFHFDAPLLWQMHGLHSPLLDRFFVLISKLGYEWFLIPADVLIIGALL
                     GYRRWREATFVAVSFVGSALLNMGSKHFFQRQRPSLWESIAPESTFSFPSGHAMGSMTL
                     AVTLVLLAWNTRWRWPVLLLAPAFSLLVSVSRVYLGVHYPSDILAGWCAALVWVVGCYL
                     VMFSRRHPWRRHGPPPAKASEASSQGD"
     CDS             16835..17023
                     /gene="allorf_023910_024098"
                     /locus_tag="allorf_023910_024098"
                     /protein_id="allorf_023910_024098"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRDVYVIDQLFRCSRFCKTGGKHNARYCDAQGRLPGSHSERACRG
                     IGTPPSLTCNGRIRRGT"
     CDS_motif       16835..16945
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MRDVYVIDQLFRCSRFCKTGGKHNARYCDAQGRLPGS"
                     /locus_tag="allorf_023910_024098_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       16946..17023
                     /prepeptide="core"
                     /locus_tag="allorf_023910_024098_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.30"
                     /molecular_weight="2605.9"
                     /monoisotopic_mass="2604.4"
                     /core_sequence="HSERACRGIGTPPSLTCNGRIRRGT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRDVYVIDQLFRCSRFCKTGGKHNARYCDAQGRLPGS"
                     /leader_location="[16834:16945](+)"
                     /alternative_weights="2624.0"
                     /alternative_weights="2642.0"
                     /alternative_weights="2660.0"
     gene            17024..17671
                     /locus_tag="PQS91_RS16955"
                     /old_locus_tag="PQS91_16950"
     CDS             17024..17671
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /function="Response regulator containing a CheY-like
                     receiver domain and an HTH DNA-binding domain"
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011408972.1"
                     /locus_tag="PQS91_RS16955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16950"
                     /product="response regulator"
                     /protein_id="WP_004153112.1"
                     /transl_table=11
                     /translation="MTIRVYLVDDHALVRTGMKMILSGETDIEVVGEAETGEDALREVR
                     QLLPDVVLCDLHLPGVSGMEVTERIVRSHRNTRVVIVSVLEDGPLPKRLLEAGAAGYIG
                     KGCDAQELLRAVRDVAGGRRYLGTSIAQNLALSTVEGNGSPFDSLSPRELEVALLLTQG
                     LRQEDIARRLSLSAKTVNTHKARLFEKMGIHDNIALARMASQYGLVDPARPL"
     misc_feature    17046..17059
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.9"
                     /tool="antismash"
     gene            complement(17770..18429)
                     /gene="eda"
                     /locus_tag="PQS91_RS16960"
                     /old_locus_tag="PQS91_16955"
     CDS             complement(17770..18429)
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /GO_function="GO:0008675 -
                     2-dehydro-3-deoxy-phosphogluconate aldolase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008700 - 4-hydroxy-2-oxoglutarate
                     aldolase activity [Evidence IEA]"
                     /GO_process="GO:0009084 - glutamine family amino acid
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0009255 - Entner-Doudoroff pathway through
                     6-phosphogluconate [Evidence IEA]"
                     /codon_start=1
                     /gene="eda"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265926.1"
                     /locus_tag="PQS91_RS16960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16955"
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="WP_049400946.1"
                     /transl_table=11
                     /translation="MGIEQHQVKAAELLHAAGILPVVTIHTLDQARAVSAALLEGGLPA
                     IELTLRTPVAMEALAMLKRELPDVVVGAGTVLTVEQMQQSIDAGADFLVTPGTPPALAD
                     ALAAAPLPVVPGAATPTELLSLYARGFRVCKLFPATAVGGLAMIKGLAGPVADLKLCPT
                     GGITENTAAEYLEQKNVVCIGGSWMVPGNWIANGEWDKVRASAADAAKIIKRVRGH"
     misc_feature    complement(18397..18406)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     misc_feature    complement(18627..18642)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.9"
                     /tool="antismash"
     gene            complement(18635..20551)
                     /gene="edd"
                     /locus_tag="PQS91_RS16965"
                     /old_locus_tag="PQS91_16960"
     CDS             complement(18635..20551)
                     /EC_number="4.2.1.12"
                     /GO_function="GO:0004456 - phosphogluconate dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009255 - Entner-Doudoroff pathway through
                     6-phosphogluconate [Evidence IEA]"
                     /codon_start=1
                     /gene="edd"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015472018.1"
                     /locus_tag="PQS91_RS16965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16960"
                     /product="phosphogluconate dehydratase"
                     /protein_id="WP_010484327.1"
                     /transl_table=11
                     /translation="MSLHPQLQAITERVIRRSAASRAAYLAAIDASLREGPFRSRLSCG
                     NLAHGFAACGGTDKSRLRGGVTPNLGIITAYNDMLSAHQPFETYPEQIREIARELGATA
                     QVAGGVPAMCDGVTQGRGGMELSLFSRDVIAQATAIGLSHDMFDTTVYLGVCDKIVPGL
                     LIGALAFGHLPAVFVPAGPMTPGIPNKQKAEVRERYAAGEATREELLEAESASYHGAGT
                     CTFYGTANSNQVLLEAMGVQLPGASFVNPGTPLRDALTREATERALDITALGDDFRPLG
                     RIIDERAIINAVIALMATGGSTNHTIHWIAVARAAGIVLTWDDFDELSQLIPLLARVYP
                     NGDADVNRFAAAGGPAFVFGELIKAGLMHGDLVSVARGGMADYAREPQLRDGQLVYLPG
                     LERSADDEVVRGVDNPFEHQGGLRLLRGNLGKSLIKLSAVKPQYRTIEAPAVVVDAPQV
                     LNKLHAGGLLPQDFVAVVRYQGPRANGMPELHSLAPLLGLLQNQGRRVALVTDGRLSGA
                     SGKIPAAIHVTPEAARGGPLAKVREGDMIRLDGEAGTLEVLVDAAEWAARPLAPNTAPA
                     AHDLGRNLFAINRRMVGPADQGAISISCGPAAADGGPWDYDAEYELGHDAAAAAAPHEA
                     KDA"
     misc_feature    20510..20523
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.77"
                     /tool="antismash"
     gene            complement(20610..21332)
                     /gene="pgl"
                     /locus_tag="PQS91_RS16970"
                     /old_locus_tag="PQS91_16965"
     CDS             complement(20610..21332)
                     /EC_number="3.1.1.31"
                     /GO_function="GO:0017057 - 6-phosphogluconolactonase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pgl"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479767.1"
                     /locus_tag="PQS91_RS16970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16965"
                     /product="6-phosphogluconolactonase"
                     /protein_id="WP_010484329.1"
                     /transl_table=11
                     /translation="MSPTFHDDRIEFISHGDADGWIEAVAAEMAQTLNHDINEVGRARI
                     LLSGGTTPAPVYQALAELDVHWDRVEVSLADERWLSPQDRDSNAWLVREHLLKRAEGAH
                     FDPLVRIGKPLPECVYTANLQAQHSQPPSLVALGMGNDGHTASLFPGSKDLARALESTL
                     PYAALDATGCPGANQWPLRITLTPHGLGQCRQRLLLLRGKQKLQVLRQALDSNDAQQYP
                     ILNAINLDGARLRVHWAD"
     gene            complement(21329..22336)
                     /gene="glk"
                     /locus_tag="PQS91_RS16975"
                     /old_locus_tag="PQS91_16970"
     CDS             complement(21329..22336)
                     /EC_number="2.7.1.2"
                     /GO_function="GO:0004340 - glucokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005416128.1"
                     /locus_tag="PQS91_RS16975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_16970"
                     /product="glucokinase"
                     /protein_id="WP_272774463.1"
                     /transl_table=11
                     /translation="MSASSQPVLVADIGGTNARFALADTSQDAPLQKDSIREYAVAEFP
                     SLGDAARHHLEQIGATASRGVFAVAGRVDGDEARITNHPWVISRSRTAAMLGFDVLHLI
                     NDFAAQAMAISLLQPDDVVQVGGAAWVPGKPGQPRNYAVIGPGTGLGVGGLILRHGRCY
                     PLETEGGHVSFPPGTPEEIRILEILSEQFGRVSNERLICGPGLVNIHRAVCEMAGIDPG
                     QLQPVDVTARALHGDPQAMRTVDVFCAVFGAIAGDLVLTQGAWDGVFLTGGLTPKMLDS
                     LQHSGFRQRFEHKGRFSSIMARVPSLAVMHPHAGLLGAAAYAADAERDAPGVAA"
ORIGIN
        1 gtcaatccgt atccaccgtc cgcgtgctgt cctacgccct gcttgcggtg gccgttgccg
       61 ccggcaccac cggctgcttc aagcgtggtg tcaagggcga ctacgccctg gccccggaaa
      121 tgcgtccgct ggaagtgccg ccggacctga acctgccgac caccaccggt gacaacaagg
      181 tgccgacgct ggcatcggcg accaagccgg cggccccggt ggctgcggcc ccggccgtgg
      241 gcaacaccgg tttcaccatc gccggtggca aggacgaagc tttcgccaag gtcggcaccg
      301 cgctggaagg cgtggaaggc gtgaccatcg ccagccgcgc gcagctgctg ggctcgtatg
      361 acgtggccta cgaaggcagc aacttcctgg tccgcgtggt cgccgtcgat gctggcgcct
      421 acatctccgc ggtcgacccg cgtggcctgc cggccaccgc cgaagcgccg gtgaagctga
      481 tcgctgcgct gaaggcgaag ctggcgcagt aagggctggt cgggtggggg cgggccttgg
      541 tccgcacccg ctctggtgga ggccgacctt ggtcggcgct tctgtgccaa ccaaggttgg
      601 cacctgccgg atcgcaaggt tggcataccg gatcttgcgg ttggcgttta ccggaaaaca
      661 gaaaagggcg cccgtgggcg cccttttcgt tgccgccgtg ggcgcttctc agcgctccag
      721 cagcttcagc ttgtccggct tgccgtccca ttcgccggca tcggcgggcg ggtccttgcg
      781 cacggtcagc accggccact ccttcgccag ctcggcgttg agggccacga aactttcctg
      841 gccggcagga acatcgtcct ccgggaagat cgcgttgacc gggcattccg gttcgcagag
      901 ggtgcagtcg atgcactcat ccgggtcgat caccaggaag ttggggcctt cgtggaagca
      961 atccacgggg cacacttcca cgcaatcggt gtgtttgcac ttgatgcagt tttcggtgac
     1021 gacaaagggc atgggctggg ggtggatcga ttcctgaacc cgccaattct agaacaggtt
     1081 ggcccccggt gtcggtgcgg ggcggaaatc gggtgtctgg caggcgcggc cgtggcggtc
     1141 attggcggca gggcgaggcc tgtgcgacgc tgcgggtcag ccggctgcgt cggatggccg
     1201 gaccccttcc cagcaggatc gtccatgtcc ccagcccagc ccaacatcgc ctcccatggc
     1261 ggtgagaaca ctgcattcat cgtcctgatc agctgcgtgg ccaccctggg tggattcctg
     1321 ttcggcttcg acagtggtgt catcaatggc acggtcgatg gcctgcgcca ggctttcaac
     1381 tccagtgagg cggcgctcgg tttcgaggtc gcctcgatgc tgctgggctg cgcgatcggt
     1441 gccttcctgg ccggctggct gggagatcgc ctgggccgtc gtggcgtgct gatcgcctca
     1501 gcgctgatgt tcctggtttc ggcgctgggt gccggtgccg cacacgcctc ctggttgttc
     1561 attgccgcac gcgtgctcgg cggcttcgcg gtgggcgcgg ccagtgtgat gtcgccggcc
     1621 tacattgccg aggtggcttc ggcgcgctat cgcgggcgtt tggccacggt gcagcagatg
     1681 gcgatcatct gcggcctgtt cgccgccttc ctcagcaatt acctgctggc ccgtgccgct
     1741 ggggcgtcga ccgagccgct atggctgggc catgaggcct ggcgctggat gttctggatg
     1801 caggcgctgc cgtcggggct gttcctgctg ttgttgctgg tgattccgga aagcccgcgc
     1861 tttctggtcg tgaaggggcg tcagcagcag gcgagggcgg tactgtcgcg gctgtacggc
     1921 gaggtcgctg cggcggccaa gcaggccgag atcgaagcca gcctggcgca ggaccagcac
     1981 aagccgcgct ttgccgacct gcgcgacacg gtcagcggca agctgcgccc gatcctctgg
     2041 gtgggcatcg gcctggccat gttccagcag ctggtcggca tcaacgtggt gttctactac
     2101 ggcgcggtgc tgtggcaggc ggtgggcttc tcggaaagcg atgcgctgct gatcaacgtg
     2161 ctgtccggcg cgctgagcat cggcgcctgt ctgctgacgg tgctgttgat cgaccgcatc
     2221 gggcgcaagc cgctgctgtg gatcggttcg gtcggcatgt cggtggcgct ggtgctgatg
     2281 gtggttgcct tcgccagtgg cagcctggcc gacggtcgcc tgcagttgtc cgacggcatg
     2341 ggccgactgg cgctggtggc agccaacgtc tacgtggtgt tcttcaacat gtcctggggc
     2401 ccggtgatgt gggtgatgct gggcgagatg ttccccaatc agatccgtgg tccggcgctg
     2461 gcggtggccg gcgccgcgca atggacctcg aacttcgcga tcaccgtgac cttcccgatg
     2521 ctgctggccg gcatcggcct ggccggcgcc tacggcatct atacggtggc ggccatcctc
     2581 tcgatcgtct tcgtggtccg ctacgtgcgc gagaccaagg gcaaggagct ggagcagatg
     2641 gaaggctgac ggcgactggc ttcggttgca ttccgttggc gcctgcctgt ccagagtgtg
     2701 agggggcagg ccgccctctc caggacacgc aaaagcccat ccatggtgct cgatggcgcc
     2761 atccatggcg ccaacggtcc tggagagggc ggcccgcccc ctcctgacag tttcatggtg
     2821 cgtgcggatg cggcgaagtg ctggtcggtt gttgccgcag ctcgcgggaa accgtccaga
     2881 gtcggtgggg tcacccaggg caggaccgtt ggcgccatgg gtcgggcgca tgcgcccgac
     2941 gggttgggca ggagcccaac cctggtcttg ccgagtgcgc aggacagcgc acgcgagcaa
     3001 ggcgccatcg agcccccatg gatgggttca cggcgtgtcc tgccctgggt gaccccaccg
     3061 gctcaagccg attgcaggca ggcgccaaag cgaccaagcc gatcgatgcc attgcaaacc
     3121 ccggaaaaca gaaaagccca cacaaggcgg gctttttcgg ttcctgctgc ggcgactggc
     3181 gctccctagg ggactcgaac ccctgtttta gccttgagag ggccacgtcc taaccactag
     3241 acgaagggag cgtaactgtg tcgctgccga ggcaggagcg ctagtatatg cacctcgatg
     3301 ccattgggca atcccgaaac ttcaaccgga agcgccaaca tcatttcctc tgctacatca
     3361 ccgttcagcc tgcgcgtcat cccgcgcgac cagcacacga tctcccgcaa ggacatcagc
     3421 ccgaacgccc tgcgcgtgct ttatcgcctg cgcgatgccg gcttcggcgc ctaccttgtc
     3481 ggcggcgcgg tgcgcgatct gctggtcaat ggccaaccca aggatttcga cgtggccacc
     3541 gatgccacgc ccgaacaggt caagcagctg ttccgcaact gccgcctgat cggtcgtcgg
     3601 ttccgcctcg cccacgtcgt gttcggccgc gagatcatcg aagtcgccac cttccgtgcc
     3661 aacagcgatg acggcagcgg cgaccgcgag atggaaaacg gcatgctcgt gcgcgacaac
     3721 gtgtacggca ccatcgaaga cgacgccatc cgccgcgact tcacctgcaa cgccctgtac
     3781 tacgccatcg aggacttctc ggtgcgtgat tacacaggtg gcttcgaaga cgtccaggcg
     3841 cgcctgatga aactgatcgg cgaccccgag cagcgttatc gcgaagaccc ggtgcgcatg
     3901 ctgcgtgcgg tgcgcctggc ggccaagctc ggcttccaga tcgaagaggg caccgccgcg
     3961 ccgatcccgc acctggctgg cctgctcaac gaagccgcac cggcacgcct gttcgaggag
     4021 gtgctcaagc tgttcctgtc cgggcacggc gtggccagct tcgaaggcct tgagcgttac
     4081 ggcctgctcg acgtgctgtt cccggaaagc gccaaggcat tgaagtccaa ccgcaccggt
     4141 gcgctgcgcc gcatgctggt cgagggcctg gccaacaccg atgcgcgcgt ggccaacgac
     4201 gagccggtct cgccggcgtt cctgttcgcg ctgctgctgt ggccggcgtt ctgccgcgcg
     4261 caggcgaccc tgctcaagca gggcgtggca ccggaggagg cacagcgccg tgctgccgac
     4321 cgtgtgaccg tgcagcagct gagcaccatc gcattgccgc gccgcttttc gctgccgatg
     4381 caggaaatct ggctgctgca gtcgcgcttc agttcgcgcc agcgcaagcg cgtgttccgt
     4441 accctgaccc acccgcgctt ccgcgccgcg ttcgatttcc tcagcctgcg ccaggtcgct
     4501 tcgtccgagc atgcagtgga tgtcgagttc tggcgcgaag cacaggcgca gtccggtcgc
     4561 gagctggagt cgtcgctgga tgcgatgcac agtgaagacg gcgatgacga gagcggggca
     4621 ccgcgcaagc gccgccgtcg gcgtcgacgt cccggtgctg ctgcggcggg cgagtaagcg
     4681 atgaccttgg cctggatcgg cctcggcgcc aaccttggcg acgcggccgc gaccgtgggc
     4741 gcggcgattg ccgcgctgga cggcctgcca ggaacgcgcc tgcgacaggc ctcgaggctg
     4801 tacgccacgc cggcgtgggg caatgaagac cagccgccgt tcgtcaacgc ggtggcctcg
     4861 gtcgaaacca cattgccggc cgatgagctg ctgcaggcga tgctggcgct ggagcggggc
     4921 tttggccgcg tgcgcgatcc ggcggtgcac tgggggccgc gcgcactgga cctggacctg
     4981 ctgctgtatg gcgcgcaggt gctcgaccat cccggcctgc aggtaccgca tccctacatg
     5041 cacgagcgtg ccttcgtgct ggtgccgctg gccgaaatcg cgccggatct ggccattccc
     5101 ggccatggcc gcgtgcagga tgcagtgatg cgggtggatg cctgcgggat cgcgccgata
     5161 gggtgataat gcccgggtta tctcccccgg ttatcagcac atgagcaccc acgcagacag
     5221 caagccctgg accgttcccg ccctggccga ggccaagcgc aatggccaga agctggtcat
     5281 gttgaccgcc tacgacgccg gctttgcccg taccttcgat gccaatggcg tcgacctgat
     5341 cctgatcggc gattcgctgg gcatggtcgt gcagggccat gattcgaccc tgccggtgac
     5401 cgtggccgac atggtctacc acacccgcgc cgtagcccgt gtgctgcagc gtgcgctgct
     5461 ggtggccgac ctgccgttcg gtgccgatgc caccccggag cgcgcgctgg atgcttcgct
     5521 gcagctgctg caggccggtg ccgagatggt caagatcgaa ggtgccggct tcaaggtcga
     5581 catcatccgc tacctggtcg agcgtgagat tccggtctgc tcgcacctgg gcctgacccc
     5641 gcagtcggtg ctgcgcctgg gcggcttcaa gatccagggc cgtggcgatg ccgcgcgcca
     5701 gctggtggaa gatgccaggg ccgtggccgc tgccggcgcc agcatcatgg tgctcgaatg
     5761 cgtgccgacc ccggtcgccg ccgaagtgac cgcggcggtg gatgttccga ccatcggtat
     5821 cggtgccggc ccgcagtgcg acggccaggt gctggtgctg cacgatttcc tcggcctgga
     5881 cagtggccat cgccgtccca agttcgtcaa ggatttcctt gccgaaggcg gttcggtggc
     5941 cggtgccacc cgcgcctatg ccgacgccgt gcgcgacggc agcttccccg acgaacagca
     6001 cgcctacgcc caatgatcca gaccttcaac gagctcggcg cgctgcgcga gcagatcgcc
     6061 cagtggaagc gcgagggcct gcgcgtggcg ctggtgccga ccatgggcaa cctgcatggt
     6121 ggccaccatt cgctggtgac cctggcccgc cagtacgccg acaaggtggt gacgagtatc
     6181 ttcgtcaacc cgacccagtt cgggccgaac gaggacttca gccgctaccc gcgcacgccc
     6241 gaggctgacg tggccgggct ggagcaggcc ggctgcgatg cggtgtggct gcccagcgtc
     6301 gaggcgatgt atccgctggg cgtggacaag accacgcaga tgcacgcgcc gggtgtcagt
     6361 gaagtgctgg aaggcgccag ccgcccgggc cacttcgacg gcgtgtgcac ggtggtggcg
     6421 cgcctgttcc tgcaggtgca gccggatgtg gccgtgttcg gtcgcaagga ttaccagcag
     6481 ctggcggtca tcaagcagat ggtggccgag ctgtcgttcc cgatccagat cgtcggcgcg
     6541 gacatcgtgc gcgacgagga cggcctggcc aagagctcgc gcaaccagta cctgagcgcc
     6601 gaacagcgcc cggtcgcgac gagtatccac cgcacgctgc tgggcatgcg cgaaggctac
     6661 gtggccgggc acacgcgggc gcagatcgag gccgacgcaa cggcggcgct gcaggcagcc
     6721 ggtttccagg tcgactacgc cgtgctgcgc acgcccgagc tggccgagcc gaccttcgac
     6781 ggcggtggcc gcgtggcgct gatcgccgcg cgcctgggca caacgcgcct gattgacaac
     6841 ctggagttct gagccgcacg cggcttgggg gcgcccgcaa cgggcgcctc tgcacttccc
     6901 acggacggga gaccggaaat gaaagcccct agcactgata ccggccgcct cgcccaggcc
     6961 tcgatcctgg cggtgctggc ggcaggcatg ttgccggccc agctgtttgg cggcctgttg
     7021 ttcgcgctcg aattcaggcg tacgccgatg cctgcgctca ccggtggtgg gctgatgttc
     7081 gtactggccg tctgcaatgc catcgcggtg ttgctgccga tggcgctgat cctgcagtct
     7141 cagcagcgcc tgcgccgggc cggcttcgtg ctggtcggct tcgggctggg cgcgctggcc
     7201 atggccacct gcgcctggcc gggagaaaac caggggccct ggctgcagcg cctgcgctac
     7261 gtcgatacct tcgatgtgat cagctatgcc ttgcaggtgc tggccgcggg aggcttcggg
     7321 ctggtcgccg ggctggcctt ccatacggtg ttccggctgt ctctggaagg cggttccggg
     7381 cacgcagcgc cgccgccgcc gggggagggc acctgaacag ccttcagcgt cctgctgcag
     7441 ccccctgacg atggtcaagc gggtgctaga atccgctctt tcctttgccg ttgcagcgcc
     7501 cccatgcacc tgtccctgct caagaccaag atccaccgcg ccaccgtcac ccattccgag
     7561 ctgaactacg aaggctcgat cgccatcgat gacaacctgc tggctgccac cggcatccgc
     7621 gagttcgaac aggtgcacat ctgggacgtg accaacggtg cgcgcttctc gacctatgcc
     7681 atccgcgccg aagccggcag cggcgttgtc tcgctcaacg gtggcgccgc gcgccacgtg
     7741 caggtcggcg acatcatcat catcgccgcg ttcgccagca tgaccgagca ggaagctgac
     7801 agcttcaagc cgaagctggt gtacgttgat ggcaagaacc agatcaccca caccaacgac
     7861 acgatcccga cccaggccgc atgacaacga acaacggatt cgactcgctg cattcccatg
     7921 cccagcgcct gaagggcgca agcatcccca gcctgctcgc cgccgaaccc ggccgcgtgc
     7981 aggatctggc gctgcgggtc ggtccgttgt acgtcaactt cgcccggcag aaatacgatg
     8041 ccgcggcgct gcaggcattg ctggctttgg ccgccgagcg tgatgtcggc ggtgccatca
     8101 cccgcctgtt ccgtggcgag caggtcaatc tgaccgaagg tcgcgccgcg ctgcacaccg
     8161 cgctgcgtgg cgatgtggtc gatgcgccgg ttgccgccga ggcctatgcc accgcgcgca
     8221 cgatccgcca gcgcatgggc gtgctggtgc gcgcgctgga agacagcggc gtcaccgacg
     8281 tggtcagcgt cggcatcggc ggttccgatc tcggtccgcg cctggtcgcc gatgcgctgc
     8341 gcccggtcag cggcgcgcgc ctgcgcgtgc atttcgtgtc gaacgtggac ggcgccgcca
     8401 tgcagcgcac gctggccacg ctggatccgg ccaggaccgc cggcatcctc atttccaaga
     8461 ccttcggtac ccaggaaacc ctgctcaacg ggcagatcct gcacgactgg ctggggggca
     8521 gcgagcgcct gtacgcggtc agcgccaacc ccgagcgtgc ggccaaggcc ttcgccatcg
     8581 ccgccgatcg cgtgctgccg atgtgggatt gggtcggtgg ccgttattcg ctgtggtcgg
     8641 ccgtcggttt cccgattgca ctggcgatcg gtttcgagcg tttcgaacaa ctgctggaag
     8701 gtgccgcgca gatggacgcg catgcactgg atgcgccgct ggagcgcaac ctgccggtgc
     8761 tgcacggcct gaccgacatc tggaaccgca acctgctggg ccatgccacg cacgcggtga
     8821 tgacctacga ccagcgcctg gcgctgctgc cggcctacct gcagcagctg gtgatggaaa
     8881 gcctgggcaa gcgcgtgcag cgtgacggac agccggtcac caccgacacc gtgccggtgt
     8941 ggtggggcgg ggcgggcacc gacgtgcagc acagcttctt ccaggcgctg caccagggca
     9001 ccagcatcgt tccggccgac ttcatcggct gcgtgcacag cgacgatccc tacacgatca
     9061 atcatcaggc cctgctggcc aacctgctgg cgcagaccga agcactggcc aatggccaga
     9121 gcagcgacga cccgcaccgc gattaccccg ggggccgccc gagcacgctg atcctgctcg
     9181 acgcactgac cccgcaggcg ctgggcgcac tgatcgccat gtacgaacac gctgtgtacg
     9241 tgcagtcggt gatctggaac atcaatgcct tcgaccagtt cggtgtcgag cttggcaagc
     9301 agctggccag tggcctgctg ccggcgctgc agggcgagga tgtggcggtt gccgatccga
     9361 tgacccgcga gatcctggcg cagctgaagg gctgacccgg cctgcggatg tgccggcgcc
     9421 ggccggccat cccatgcctc tccggttgcc ttcgatccgg tcgcgcatga gtgtctgcgc
     9481 ggccactcat tccgtcctgt ttccgtgctg cacatgccgc gcatccgcgt gcctgccgca
     9541 gcgcagcttg actgcgcatc gcgtgccaat gcagtgtgca cgggcggctg tacctgtcat
     9601 ccagtatcgc tcgcagcatg aagttgatgc cagggactgg ccgtatccga agggacgtgg
     9661 aatcgatcca tgtcctcaac gcctcatgtt gtgaatgaca ggagattgcg aatggatctg
     9721 aatgacgatg ttgtgtccgg ctggctcaat ggctcggacg atgtggatgg gtgcgccaac
     9781 cctgcgggtt cgctgttcat ctacggtgcg gcagccaccg aagcggccct caccggagct
     9841 tcggacacca tgatcaccgg gggcaccaac gagtgcacca ccacggtatc ggtgatcaac
     9901 cactgcctgt gttgctgatg taacccgagc cggcacgcag aggcatgcag ctgcgtgccg
     9961 gcgactggaa cagacttccc gataccttgc agggggcgta atgaccgctt ctccggctgc
    10021 ggctgcgttt gcgcgcatca ccgaacattt ccttgcccat gcgcgcgccg cgttggcgac
    10081 tggcctgcat gaccctgcca ttgcactgca gcccggtgag cgcgaactgc tgcacgcgca
    10141 cggcgacgcg gcgctgcgtg agcatgccca gctcaagctc aaccgcgtgc tgctgctgga
    10201 actgcacgcc gctgcacgca gtggtgacat cggcccgctg ggcagtgcgg gtgcgctgga
    10261 cgaattcgtt gccctggcca cgagcgaggg cttccgtacg catctgcagc gacgctatcc
    10321 ggtgctgctg ccgcgcctga cgcgcatgct cgaaggacaa tgtgcggcgg tggtggagct
    10381 cgctgtgcgc atcggcagtg atcgtgcggc gctggcaggg ttgctgggcg cgccggcggg
    10441 cacgctgcat gccgttgcat tgggacgggg tgacctgcat ggtggcggcc ggactgtggc
    10501 acggctgcag ttcgaaggcg gcacggtgat gtacaagcca cgctcattgc gcatcgatgc
    10561 gacgctcgac ggcctgttgt gcacgctctt cggtgacggc cctgaccgcg tatgcgtgcc
    10621 gaaggtgatt gatcgtggca gccacggctg ggccgccttc gccgcgcacc gctactgtgc
    10681 cgatgacgtt gaactgcgtg cctactatcg cggtcttggc cattggctgg cgatcctgcg
    10741 cctggtgggt ggcaccgaca tccatctgga gaacctgatc gcggtcgggc cggtgccggt
    10801 tgtgatcgac gccgaaagcg tgttctcccg ggtaatcgaa atcgagccgt caggacttgg
    10861 cgatgcgtac gacaccgccg tcaagctgat gcgcaattca gtgctgcgta ccggaatcgt
    10921 gccgttccgt actgccggcc tgggcatgga aggcgtggat ctgtctgcag ccggcgcact
    10981 gccgggcgag cagccgcggg tgcaggtgcc ggtgattgtc gagggcggga cggaaccggc
    11041 ccggttgggc atggtcgagg ccgaggtgtc cgttgcgcag aatcatccca gcgcgcagcc
    11101 cgatgtgtcg ttgtactggg accacatcag cgagggcttc atcgacgcca gtgggcgcct
    11161 gcgcgcgctc gatgccaagg gcgaactgat gccactcctg gcggctttcg aaggctgcca
    11221 ggtgcgcgac gtgcggcggc cgacaatggc ctacgcagag ctcgggcgga tgctctggca
    11281 tccagcctcg ctgcacaacg aagcccaggc ggttgaacgc gcgatcgatc tgctggtgcg
    11341 caatgcagcg gtgtcaccgg ctgcgccatc ggacctggac accgtccgta gcgaagtgga
    11401 tgacctgcgc cacggtgaca ttccgatctt cacttcgcag ctggacgcag cgcgcatccg
    11461 ctccatcgcc gacaactggc gtgcgatgcg catcgacctg gaagacgtga ccatccgcag
    11521 cacgctggtg gccaccgacc tgaaccagca tgcgctggcc cgcgccgagg ctcgatccgg
    11581 ctacagctat gccgcacagc atccgcgtgc ggacgacctg gacgcgcgcc gtcgtacgct
    11641 ggccgcgcgc gcggtggaga gcctgctgcg gctggcggtg catggtgagg acggttcgat
    11701 gacctggatc acccccgagg tgacccgtac cggatggacc gtccagccgg tgcagcccga
    11761 cctgtatttc gggctgggag gtattgcatt cgcattggcg gcttaccacc gggaagtgga
    11821 gcaggggcgt gccgacccgg tagcggggct gggcccggcc atcgatggcg cccttgcggt
    11881 gttccagacc atgtgtgagc agcaccccgc cgagatcgat ggtggattcg tcggaaccgg
    11941 ttcacagata tggacattgc tggcattgca cgacctcttg cagcgaccgg cgttgctggt
    12001 gctggcggaa cgttgtgcgg aagccgcaga gcgtcgcggc ttccaggagg cgacaaagtt
    12061 cgaactgatt gatggcgtgt ccggcatgat cctgccgttg ctgtcgctgg ccgcggctac
    12121 cgggaacgca cgctggctgg agctggccgc cgcagcgggg cgtcgcatgc aggaagcggc
    12181 gatcgtcgat gccgacggcg cacgctggcc gacgccacag ttccgagagc cgatcggtgg
    12241 cttcggccac ggtgcgatgg gcatgggctg ggcgctggca cggctggcgc gttcggatgc
    12301 cggcagcgtg cctgagcgag cggcctggcg gcagttggcc gaaggagcgt ttgcgttcca
    12361 ggcggcgctg ttcgaaccgt ataccgggca ctggcgtgac atccacctgc aggatgggca
    12421 gaagaacttc ccgacctggt gccatggcag cgttggtatc ggtctggcgg cggcggatct
    12481 gtatgcccgc accggcgatc ccgcgcagtt gcgtgacatg cggcgggctg tggccgacgc
    12541 gcgcggcaaa tgggggttca gccacaccct gtgccacggc gatgtgtcca cccgggagct
    12601 gctggtgctg gcggctgcgc tggatccgga gggatgtccc tatccgcagg atgaggcggc
    12661 tatcgagatc gtttcttcaa tcgaggagca ccagggcatg gtcggcggac tgacccgcgc
    12721 ggccttcact ccgggcctga tgatcggcct ggcaggtgcg atctatggtt tcctgcgcat
    12781 gcatccggcc tgcgcgctgc cgtcgccgtt gctgcaggag acgacagtgg cccgggtcga
    12841 tgcaccggca tcgcgttcca gtaccgcgca ggaccgagcg gtgctggccg aggtctgagc
    12901 cggacggggc cggtcgcgat caacggctgg gatcgcgctc cgggctcggc cgcttggcca
    12961 gcttgcgctg cagagaacgc cggtgcatgc cgagcaggcg tgcggccgcc gatacgttgc
    13021 cgccggtctc atgcatcgcc tgctggatgt gctcccactg caggcggctg atcggcgtca
    13081 tcgcgtccgg cacttccatt tcgccatcgt cggccgggcc gtcatcttcc tcgccgaggg
    13141 cgcgcaggat catcggcacc gtggccggct tcggcagata gtcatcggcc ccgagcttga
    13201 tcgcttcgac cgccgtggcg atgctggcgt agccggtgac cagcaggatg cgcatgtccg
    13261 cgcgcagcgc gcgcagtggt tggatcagtg ccaggccgga atcgctgccc agcttcaggt
    13321 cgatcagcgc gaacgccggc ggatgctggc gggccagtgc cagtgcactg gcggcgtcct
    13381 gcgcggtctg ggtttccagc cccttgcggg ccaggctgcg ctgcagggta cgcaggtaca
    13441 gctcgtcgtc gtcgaccagc aggcccaggg tggagtggtg aaggctcatg gggtgtcctc
    13501 gcgtggggtc agcggcaggc ggaagccgac gcggctgccg gccccctggg ccgggcgcat
    13561 ccacatctcg ccgtcgaggc gttcgatggt ggcatgggac agggccaggc cgacgcccat
    13621 gccctcgctt ttgctgctgc cgaacagctt gcccggcagc accgcggcgc gggcgtcgaa
    13681 gccgtggccg tagtcgcgga cttcgccgat caggtcgtcg ccttcgatgc gcaggtccag
    13741 gtccacgcgc ggccggccgg cctgttcgcc ggcatcagcg gcattgttga gcaggaccat
    13801 cagcagatgg cccacgcccg ggtcgagtgg cagccgcagc ggcgcatcgt cgttgcggtg
    13861 caggtcgatg gtcggccgca ccaggcgcca ctgttccagt acctgctgcg cgctggagtg
    13921 gctgcgcccc ggtgcatcgg ccgaggccgg tgcggccagc gccagcacgc gctcacggca
    13981 ctgcaccagc agctcgcgca gggtttccat gtcttcgcgg acttcgggct cttcgctgcg
    14041 ctcggcgacg tcatcggcga gcagggtcat ggtcgccagc ggcgtgttca gttcatgtgc
    14101 caccgaggcg gcatgggtgg ccagggcgac aatgccctcg ttgcgggcga agcgttcgcg
    14161 cagggccgac agttccagtt cgcgctggcg cagcgccagt gccaggcggg tggagaaggt
    14221 cagtacgacc gcagcggaaa tcaggaaatt ggcgaccacg ccccagcggt tgaggtcctg
    14281 cgcgcggaaa tagccatccg gcagcgactg gccgaagatg ccgctggcgg cgtagccgag
    14341 caggcaggcc agcgcgaccg ccagcgccca gcgcaggggc agggcgaacg cggccagcgc
    14401 gatcaggatc aggaacagcg aactgaacgg gttggccatg ccgccgctcc agcccaccat
    14461 ccaggtcagg atgatcacgt ccaccaggat gtggccgaat gcggtcagtg gcgcggtgtc
    14521 ggctgcttcc gggcgcagct gggtgtagat gttgaacagg gtcagcacgg ctacgccggc
    14581 ccacagcggc agctgcggca acggcaggcc cagcacccag gtggcgacca ggatggtggc
    14641 ggcctggcca cctacggcaa gccagcgcag gctgcacagg gttcggagaa acggggcgtc
    14701 gggaccggtc attcacgctc atcgtatgcg ttcacgcgtg accgtgcctg cgacaatcgg
    14761 ccgcagccgt gccgccggct gaatgcgagt cacccggaat gcgggagcgg gcggtagaat
    14821 gcgcccatgc acgacgccgt cacccgcccg actcccccct ccgatgccac ctcctggccc
    14881 cgccgccaga cccacgccgt gcagatcggc ggggtcaccg taggtggagg caagccggtg
    14941 gtggtgcagt cgatgaccaa caccgacacg tccgacgtgg cctccagcgt gaagcaggtg
    15001 gccgagctgt ggcgtgcggg ttcggaaatg gtgcgtttga ccgtcaacac cgttgaagcc
    15061 gctgcggcga tcccgcgcat cgtcgacaag ctggcgatga tgggcatcga cgtgccgctg
    15121 atcggtgact tccactacaa cggccaccag ctgctgaccg ccgagccggc gtgtgccgaa
    15181 gcgctggcca agtaccgcat caacccgggc aacgtcggct tcggcaagaa gaaggacctg
    15241 cagttcgccc agttgatcga gttcgcgatc cgctacaaca agccggtgcg catcggcgcc
    15301 aactggggct cgctggacca ggccctggcg gcgaagctga tggacgagaa caacctgcgc
    15361 gaacagccct gggacgccgg tcgcgtgctg cgcgaggcgc tgatccgctc ggcgctggat
    15421 tcggccgagc aggcagtgga actcggcctg ccgcgcgacc gcatcgtgct gtcggccaag
    15481 gtcagcggcg tgcaggaact gatcgcggtg tatcgcgacc tggcccagcg ctcggacttc
    15541 gccctgcacc tgggcctgac cgaggccggc atcggcagca agggcatcgt cgcctcgtcc
    15601 gcggcgctga gcgtgctgct gcaggaaggc atcggagaca ccatccgcat ctcgctgacc
    15661 ccggaaccgg gccagtcgcg cacgcaggaa gtgatcgtcg cccaggaact gctgcagacc
    15721 accggccagc gtgccttcac gccgctggtc acggcctgcc cgggctgcgg ccgcaccacc
    15781 tccgagttct tccaggagct ggccaaggtg gtgcagaacc acgtgcgcga gaagatgccg
    15841 ctgtggaaga tccaccaccc gggggcggag aacatgaccc tggcggtgat gggctgcatc
    15901 gtcaacgggc cgggtgagtc gcgccatgcc aacatcggca tctcgctgcc gggcacgggt
    15961 gaaacgcctg cagcgccggt gttcgtcgat ggcgagaaga aggtgaccct gcgtggcgac
    16021 aacatcgccc aggagttcgt cgccctgatc gacgattacg tcgaacacaa gtatgtccga
    16081 agcgccggat aagcctgcga tcctcgctgc accggagtcc gcctccggct tccgccactg
    16141 gatggcgcgc aacgcctggc gcctggtcct gctgttcggc ggtgtgttgc tgccgctggc
    16201 cggcttcgtc gccctggctg acgaggtgca cgagtttgaa tcgttccatt tcgacgcgcc
    16261 gctgctgtgg cagatgcatg gcctgcattc gccgctgctg gaccgcttct tcgtgctcat
    16321 ctccaaactg ggctacgaat ggttcctgat cccggccgac gtgctgatca tcggcgcgct
    16381 gctgggctac cggcgttggc gcgaggccac cttcgtggcg gtcagcttcg tcggctcggc
    16441 gctgctgaac atgggcagca agcacttctt ccagcgccag cgccccagcc tgtgggaatc
    16501 gatcgcgccg gaatcgacgt tcagcttccc cagcggccac gcgatgggct cgatgaccct
    16561 ggcggtgacc ctggtactgc tggcctggaa cacccgctgg cgctggccgg tgctgctgct
    16621 ggcgccggca ttcagcctgc tggtcagcgt gtcccgggtc tatctggggg tgcattaccc
    16681 ctccgatatc ctggccgggt ggtgtgccgc gctggtttgg gtggtagggt gctatctggt
    16741 catgttcagt cgccggcacc cctggcgacg tcacggcccg ccgccagcga aggccagcga
    16801 agcatcatca cagggggatt gacgtggatg gcccttgagg gacgtctacg tgatagatca
    16861 gttgtttcgt tgcagcaggt tctgcaagac agggggcaag cacaacgcgc ggtactgtga
    16921 tgcgcagggc agattgccgg ggtcgcattc cgaacgcgct tgcaggggta tcggcacccc
    16981 acctagcttg acctgcaatg gccgcattcg aagaggtacg tgaatgacga ttcgagtcta
    17041 cctggtggat gaccacgcac tggtccgcac cggtatgaag atgattctgt cgggggaaac
    17101 cgacatcgag gtggtgggcg aagccgagac cggcgaggac gcgctgcgcg aggtccgcca
    17161 gctgctgccg gacgtagtgc tgtgcgacct gcatctgccg ggtgtgagcg gcatggaagt
    17221 gactgagcgc atcgtgcgca gccaccgcaa tacccgcgtg gtgatcgtgt cggtgctgga
    17281 agatggcccg ctgccgaagc ggctgctcga agctggtgct gccggctaca tcggcaaggg
    17341 ctgcgacgcg caggaactgc tgcgcgcggt gcgcgacgtg gccggtggcc gccgctacct
    17401 gggtaccagc atcgcgcaga acctggcgct atcgacggtg gaaggcaacg gttcgccgtt
    17461 cgacagcctg tcgccgcgcg agctggaagt ggcgttgctg ctgacccagg gcctgcgcca
    17521 ggaagatatc gcccgccgtc tgagcctgag cgcgaagacg gtgaacacgc ataaggcgcg
    17581 gttgttcgag aagatgggga tccacgacaa catcgcgttg gcgcggatgg ccagccaata
    17641 cgggctggtg gatccggcac ggccgctgta agggattcgg ccttccgtag agccgagccc
    17701 atgctcggct gctctccatt ccgctggagt ggagccgagc gtgggctcgg ctctacagct
    17761 gcgttcggct cagtggccgc gcacgcgctt gatgatcttg gcggcgtcag cggcgctggc
    17821 gcgcaccttg tcccattcgc cattggcgat ccagttgccc ggcaccatcc acgaaccacc
    17881 aatgcagacc acgttcttct gttcgaggta ctcggcggcg gtgttttcgg tgatgccgcc
    17941 ggtcgggcac agcttcaggt cggcgaccgg gccggccagg cccttgatca tcgccaggcc
    18001 acccacggcc gtggccggga acagcttgca cacgcggaag ccgcgcgcat agagcgacag
    18061 aagctcggtc ggcgtggccg cacccggcac caccggtagc ggtgcagcgg ccaatgcatc
    18121 ggccagcgcc ggcggcgtac caggcgtcac caggaagtcc gcgcccgcat cgatcgactg
    18181 ctgcatctgc tccacggtca gcaccgtgcc cgcgcccacc accacatccg gcagctcgcg
    18241 cttgagcatc gccagcgctt ccatcgccac cggtgtccgc agcgtcagct cgatggccgg
    18301 caggccacct tccagcagcg ccgcactgac cgcccgcgcc tggtccagcg tatgaatcgt
    18361 caccaccggc aggatgcccg ccgcatgcaa cagctccgcc gccttcacct gatgttgttc
    18421 gatacccatg cttttgccct tgcctttgct cttcttgatt cagtggccgc agcgcagatg
    18481 acgcgccggg aattgtccaa gggcagtaga gcgccctggc cgggaccgtg agcggcatgg
    18541 atgccgcgat cgagccccca tggatgggtt tacggcgtgt cccggccagg gcgctctact
    18601 gcccaggccg ggaagcctgc cgcggctttt cgcttcaggc gtccttcgcc tcatgcggtg
    18661 ccgccgccgc agcagcatca tgccccagct cgtactccgc gtcgtaatcc cacggcccac
    18721 catcggccgc cgccggtcca cacgaaatcg aaatcgcccc ctggtcggcc ggacccacca
    18781 tgcgacggtt gatcgcaaac agattgcggc ccaggtcatg cgcggccggc gcggtgttcg
    18841 gcgccagcgg acgtgctgcc cattccgccg catccaccag cacttccagc gtgccggcct
    18901 cgccatccag gcggatcatg tcgccttcgc gcactttggc cagcgggcca ccgcgcgccg
    18961 cttccggcgt cacgtggatc gccgccggaa tcttgcccga ggcgccggac aggcggccgt
    19021 cggtgaccag tgccacacgc cggccctggt tctgcagcag gcccagcagc ggcgccagcg
    19081 aatgcagttc gggcatgccg ttcgcacgcg ggccctggta tcgcaccacc gccacaaaat
    19141 cctgcggcag caggccaccg gcgtgcagct tgttcaaaac ctgtggtgca tccaccacca
    19201 ccgccggtgc ttcgatcgtg cggtactgcg gctttaccgc cgacagcttg atcagcgact
    19261 tgcccaggtt gccgcgcagc aggcgcaggc cgccctggtg ttcgaacggg ttgtccacac
    19321 cgcgcactac ttcgtcatcg gcgctgcgtt ccaggcccgg cagatagacc agctggccgt
    19381 cgcgcagctg cggctcgcgc gcatagtcgg ccatgccgcc acgcgcgacg ctcacgaggt
    19441 cgccgtgcat caggcccgcc ttgatcagct cgccgaacac gaacgccggg ccgccggccg
    19501 cagcgaagcg gttcacgtcg gcgtcgccgt tcggatagac gcgggccagc agcgggatca
    19561 gctgcgacag ctcgtcgaag tcgtcccagg tcagcacgat gccggcggcg cgtgccacgg
    19621 cgatccaatg gatggtgtga ttggtcgacc caccggttgc catcagcgcg atgaccgcgt
    19681 tgatgatcgc gcgctcgtcg atgatccggc ccagcggacg gaagtcatcg cccagcgcgg
    19741 tgatgtccag cgcacgttcg gtggcttcgc gggtcagtgc atcacgcagc ggcgtgcccg
    19801 ggttgacgaa cgacgcaccc ggcagctgca cgcccatcgc ttccagcagc acctggttgg
    19861 aattggcggt gccgtagaag gtgcaggtgc cagcgccgtg gtacgacgcg gactcggctt
    19921 ccagaagctc ttcgcgggtg gcttcgccgg cggcgtagcg ttcgcgcact tcggccttct
    19981 gcttgttcgg aatgcccggg gtcatcgggc cggccggcac gaacaccgcc ggcaggtggc
    20041 cgaaggccag tgcgccgatc agcaggcccg gcacgatctt gtcgcacacc ccgaggtaga
    20101 cggtggtgtc gaacatgtcg tggctgagcc cgatggcggt cgcctgtgcg atcacatcgc
    20161 gcgagaacag cgacagttcc atgccgcctc ggccctgggt gacgccgtcg cacatcgccg
    20221 gcacgccgcc ggccacctgt gcggtggcgc ccagctcgcg ggcgatctcg cggatctgct
    20281 cgggataggt ctcgaacggc tggtgcgccg acagcatgtc gttgtaggcg gtgatgatgc
    20341 ccaggttcgg cgtcacgcca ccgcgcaggc ggctcttgtc ggtgccgcca caggcggcga
    20401 atccgtgggc gaggttgccg cagctcaggc ggctgcggaa cgggccctca cgcagggagg
    20461 catcgatcgc ggccagatag gcggcacgcg aggcggcgct gcggcggatg acacgctcag
    20521 tgatggcttg cagttgcgga tggaggctca ttggctaccg gcgttcgtgg tggcgagagg
    20581 caagcggcgg cgcggcgccg ccgccgacat caatcagccc agtgcacgcg caggcgcgcg
    20641 ccgtccaggt tgattgcatt gaggatcggg tactgctggg cgtcgttgct gtccagcgcc
    20701 tggcgcagca cctgcagctt ctgcttgccg cgcagcagca gcaggcgctg gcggcactgg
    20761 cccagcccgt gcggggtcag cgtgatgcgc agcggccact ggttcgcgcc cgggcagccg
    20821 gtggcgtcca gtgccgcgta gggcagggtg ctttccagtg cgcgggccag gtccttcgag
    20881 cccgggaaca gcgaggcggt gtggccgtcg ttgcccatgc ccagtgccac caggctcggc
    20941 ggctggctgt gctgggcctg caggttggcg gtgtaaacgc attccggcag cggctttccg
    21001 atccgtacca gcggatcgaa atgcgcacct tcggcgcgct tgagcaggtg ctcgcgcacc
    21061 agccaggcgt tgctgtcgcg atcctgcggc gacagccagc gctcgtcggc caggctcact
    21121 tccacccggt cccagtgcac gtccaactcg gccagcgcct ggtagaccgg cgccggcgtg
    21181 gtgccgccgg acaacaggat gcgggcgcgg cccacttcgt tgatgtcgtg gttgagggtc
    21241 tgcgccatct cggcggccac tgcctcgatc cagccgtcgg catcgccgtg gctgatgaac
    21301 tcgatgcggt cgtcgtggaa ggtgggactc atgcggcaac tccaggtgcg tcacgttcgg
    21361 cgtcggcggc ataggcggcg gcgcccagca gtccggcgtg gggatgcatc acggccaacg
    21421 agggaacgcg cgccatgatc gaagagaacc gccccttgtg ttcgaagcgc tggcggaaac
    21481 cagagtgctg cagcgaatcg agcatcttcg gagtcagacc accggtcagg aacacgccat
    21541 cccaggcacc ctgggtcagt accaggtcgc cggcaatggc gccgaacacc gcgcagaaca
    21601 cgtctacggt gcgcattgcc tgcggatcgc catgcagggc acgggcggtc acgtccaccg
    21661 gctgcagctg gccgggatcg ataccggcca tctcgcacac cgcgcgatgg atgttgacca
    21721 ggccggggcc gcagatcagt cgctcgttgg agacgcggcc gaactgctcg gacaggattt
    21781 ccaggatgcg gatctcctcc ggggttcccg gcgggaagct gacatggccg ccttcggttt
    21841 ccagcggata gcagcgtccg tggcgcagga tcaggccacc gacacccagg ccggtgcccg
    21901 gaccgatcac cgcgtagttg cgcggctggc ccggcttgcc cggcacccag gcggcaccac
    21961 cgacctggac cacgtcatcg ggctgcagca gtgaaatcgc catcgcctgt gcggcgaaat
    22021 cgttgatcag gtgcagtacg tcgaacccga gcatcgctgc ggtgcgactg cgcgagatca
    22081 cccacggatg gttggtgatg cgcgcttcgt caccatcaac gcgaccggcc actgcgaaca
    22141 cgccgcggct ggcggtggcg ccgatctgtt ccagatggtg gcgcgcggca tcacccagcg
    22201 atgggaactc cgccaccgcg tactcgcgga tgctgtcctt ctgcagcggt gcgtcctgcg
    22261 aggtgtcggc cagggcgaag cgggcgttgg tgccgccgat gtcggcgacc agcaccggct
    22321 gcgagctggc actcatgccg aggctccgct gtccggcgcg tccacgccct gcggcaggaa
    22381 ctcgcccgca ttgctcgggc cccattggcc ggcggggtag ggctccagcg gcagcttggc
    22441 gtccttccag gcatcggcca cgctgtcgat ccacgcccag gcggcgcgca cttcgtcatc
    22501 gcgcacgaac agcgtgtggt tgccgttgaa cgcatccagg aacaggcgct cgtacgcgat
    22561 gcggcggtgc aggccggtcg gcaccgacag ctccagctcc agcgggtgca gttccagcgc
    22621 gccccattcc gggccggcca ggctgctcat caggcccagt tcgatgtttt cctgcggctg
    22681 cagctggaac accaggcggt ttggtgcggc ctgcgcgcgc tgcgggcgct cgaacagcca
    22741 gtgggtgacc ggcttcagcg tgaccaccac gcgggtggtg cgctcgggca ggcgcttgcc
    22801 ggtgaccagg tggaacggca cgccgctcca gcgccagttg tcgatgtgcg cggtgacacc
    22861 ggcgaaggtc tccacgtcgc tgccttccgg cggctggt
//
