LOCUS       NZ_JAQQGI010000006     10846 bp    DNA     linear   CON 12-MAY-2024
DEFINITION  Stenotrophomonas geniculata strain BLCC-B124
            NODE_6_length_257496_cov_217.256026, whole genome shotgun sequence.
ACCESSION   NZ_JAQQGI010000006
VERSION     NZ_JAQQGI010000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Stenotrophomonas geniculata
  ORGANISM  Stenotrophomonas geniculata
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas.
REFERENCE   1  (bases 1 to 257496)
  AUTHORS   Lefler,F.W., Fernando,B., Fernando,A., Berthold,D.E., Kennedy,A.,
            Indest,K.J. and Laughinghouse,H.D. IV.
  TITLE     Draft genome sequences of cyanocidal bacteria isolated from
            cyanobacterial infested fresh waters
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 257496)
  AUTHORS   Lefler,F.W., Fernando,B., Fernando,A., Berthold,D.E., Kennedy,A.,
            Indest,K.J. and Laughinghouse,H.D. IV.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-FEB-2023) IFAS, University of Florida, 3205 College
            Ave, Davie, FL 33314, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-JAN-2023
            Assembly Method                   :: SPAdes v. 3.15.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 431x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028550615.1-RS_2024_05_12
            Annotation Date                   :: 05/12/2024 16:37:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,164
            CDSs (total)                      :: 4,091
            Genes (coding)                    :: 4,068
            CDSs (with protein)               :: 4,068
            Genes (RNA)                       :: 73
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 65
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 23
            CDSs (without protein)            :: 23
            Pseudo Genes (ambiguous residues) :: 0 of 23
            Pseudo Genes (frameshifted)       :: 2 of 23
            Pseudo Genes (incomplete)         :: 19 of 23
            Pseudo Genes (internal stop)      :: 4 of 23
            Pseudo Genes (multiple problems)  :: 1 of 23
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:51:48
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 123960
            Orig. end                         :: 134806
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAQQGI010000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10846
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10846
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10846
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5846](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5846)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            348..572
                     /locus_tag="PQS91_RS11655"
                     /old_locus_tag="PQS91_11650"
     CDS             348..572
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479411.1"
                     /locus_tag="PQS91_RS11655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_11650"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_010483459.1"
                     /transl_table=11
                     /translation="MAIVITLDRMLQERGMTLSELAGRIDITLANLSILKTGKARAIRF
                     STLDAICRELQCTPGDLLGHDPTQAQDAD"
     gene            616..2157
                     /locus_tag="PQS91_RS11660"
                     /old_locus_tag="PQS91_11655"
     CDS             616..2157
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1273: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659354.1"
                     /locus_tag="PQS91_RS11660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_11655"
                     /product="TerC family protein"
                     /protein_id="WP_029379871.1"
                     /transl_table=11
                     /translation="MEWLADPSIWMGLATLVVLEIVLGIDNLVFIAILADKLPPHQRDR
                     ARVIGLALALLMRLVLLAALAWIMKLTEPLLTLFDHSFSGRDLILLGGGLFLLFKGTME
                     LHERLEGRQHEDNGKKVYASFAMVVAQIVVLDAVFSLDSVITAVGMVDNLGVMYAAVTI
                     AMALMLVASKPLTRFVNKHPTVVVLCLGFLLMIGFSLVAEGLGYKIPKGYLYAAIAFSI
                     LVEAFNQWVRFNRERNERRQPFRQRTADAVLRMLGARPTNGHDDESADEHVDAEERLQP
                     AEHEMIRSVLGLADRPVSSVMTVRADVQWIDLARGQDDVVARLVASPHTRLLVGDGDLD
                     SLRGVVQSRDLLADLLQGKPLQLEGNLREPQYVLSSASALQALELIRQHPVPLAVAVDE
                     YGSVEGLVTANDLLAAIAGDLVDTQDERYGVVMQGEGQWEADGALTLDDLQRLAGVSLP
                     RSADYMTISGLVLERLGRLPDIGDAVEIADVRITVLAMEKRRIARLRVQRLDGMA"
     gene            2279..3415
                     /locus_tag="PQS91_RS11665"
                     /old_locus_tag="PQS91_11660"
     CDS             2279..3415
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004147841.1"
                     /locus_tag="PQS91_RS11665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_11660"
                     /product="metallophosphoesterase"
                     /protein_id="WP_032952464.1"
                     /sec_met_domain="Metallophos_2 (E-value: 6e-10, bitscore:
                     33.4, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVAVLSTIGLLMGLYVAWRLFWPLRMPTWMKVVLSLLLVGVAVQL
                     RIVAMFWGTMASPEIPKLAIATLATGSTAVLLLALLMLALDVSLLASRLLRWPRAVAAL
                     RTRSLRPAAGLLALLVSGYGISQGMAVPQPRQIDVAIKDLPAAFDGYRVLQLTDIHASR
                     LLTGDWVRRVVDQSNALTPDLIVITGDLIDGSVEARRDDARPLVDLRAPDGVVAITGNH
                     EYYAQYQAWMQAFRALHMQVLENSHMQVRRGDAALTIAGVTDPVAARYGLPLPDMDAAL
                     AGADPSAPVILLDHRPRNAREAAARGVKLQLSGHTHGGQIIGMDQLVKRANGGYVSGRY
                     EVDGMTLYVSNGAGLWAGFPARIGVPSEITLITLRRAP"
     gene            complement(3552..4190)
                     /locus_tag="PQS91_RS11670"
                     /old_locus_tag="PQS91_11665"
     CDS             complement(3552..4190)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005408497.1"
                     /locus_tag="PQS91_RS11670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_11665"
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="WP_010483452.1"
                     /transl_table=11
                     /translation="MAVSNTSSLHGWRLFVAIAVVLIAFALAAFTLQPDVVEGSRAAIR
                     VTARTSFLLFLAAFTASSFASLLPGPFTRFLLRERRIVGLSFAFSHLLHAVAITAFGIL
                     NPAFWPARSALANLPGTIGYVAILALAITSHRGIARRMGPTAWRRLHVTGMWIIAAVFT
                     YSYFKRVPGNFWYAVPSALLFTAVVVRAIAKRAQSLRRNAHARPPLRSS"
     gene            complement(4274..5008)
                     /locus_tag="PQS91_RS11675"
                     /old_locus_tag="PQS91_11670"
     CDS             complement(4274..5008)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010483449.1"
                     /locus_tag="PQS91_RS11675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_11670"
                     /product="putative DNA-binding domain-containing protein"
                     /protein_id="WP_049455587.1"
                     /transl_table=11
                     /translation="MAEPLATLQQRWADHVRDPSMPAPEGIDARRMAVYRRLCIDSLDS
                     LLAGSLPRLQAQLGDACWRDTVEHYYARHACHTPLFPQIAGEFAAWLGVQADLALPGWV
                     AELAHYESTQQALHIEARHTGQQPLHAPQAGSVLALSPLVRVLGYQWPVHEDAGQNGAP
                     TTMPTLLLLRRLGDFSLQVQELSPLAYALLSAFGDDGARAEDALQVLADLHGVAADELR
                     TACIPLLGDLCAAGVLVVPNDC"
     gene            complement(5001..5846)
                     /locus_tag="PQS91_RS11680"
                     /old_locus_tag="PQS91_11675"
     CDS             complement(5001..5846)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646321.1"
                     /locus_tag="PQS91_RS11680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_11675"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_125437823.1"
                     /sec_met_domain="DUF692 (E-value: 5.1e-119, bitscore:
                     390.3, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLPLPSASAGLGLRRGLIDELLAMPADAIDFLEVSPDNWIGVGG
                     AHGAALRQLSERHRLTCHGLSLSLGGPDPLDRTLLAQTRAFLDLHQVQLYSEHLSYCAA
                     GGHVYDLLPLPFTTEAVHHVAGRIRQVQDTLGRRIAVENISYYAVPGADMSEIEFITAV
                     LAEADCDLLLDVNNVFVNACNNGYDAFDFLARVPAHRVASLHVAGHFDEDDGFKIDTHG
                     APVKGVVWALLGEAYARVGVRPTLLERDFNFPPLAELLAEVEQIRHAQADVLPPEVAHG
                     "
     misc_feature    complement(5838..5840)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(5899..6375)
                     /locus_tag="PQS91_RS11685"
                     /old_locus_tag="PQS91_11680"
     CDS             complement(5899..6375)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005412584.1"
                     /locus_tag="PQS91_RS11685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_11680"
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_010483445.1"
                     /transl_table=11
                     /translation="MSVSTKNTAASRLPRIGAIGIALAGGLLLAGQAAAIQPLAIGAVA
                     MSAAAEGKCGEGKCGANKAATGKPAAKAKVAEGQCGEGKCGDASFARTDRDHDGRVSRA
                     EFNAVAAKRAAEFDRIDTDHDGYISEQEAHDYLRSVYTANGKPMPKGLFSRVND"
     misc_feature    6389..6402
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.9"
                     /tool="antismash"
     gene            complement(6475..7119)
                     /locus_tag="PQS91_RS11690"
                     /old_locus_tag="PQS91_11685"
     CDS             complement(6475..7119)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479418.1"
                     /locus_tag="PQS91_RS11690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_11685"
                     /product="DoxX family protein"
                     /protein_id="WP_010483443.1"
                     /transl_table=11
                     /translation="MISSASSVYTPRLDAVGRWLSPLALRALLAWEFFESGREKLGGQN
                     WFADLEGRFPFPFSTLPASLNWQLATWLELVGAVMLLLGLATRSVAYIFWVLTLVAIAA
                     VHWPDQWNSLGELWQGYAITDQGYGNFKLPLLFLAMLLPLILNGGGALSLDRLLAGPQR
                     AAAGNDGLGWGVSLIALLLPVAALLPGIGFGGALLGGALLLGYRLRRRRNA"
     misc_feature    complement(7294..7309)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.21"
                     /tool="antismash"
     misc_feature    7300..7318
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.98"
                     /tool="antismash"
     gene            7413..8207
                     /locus_tag="PQS91_RS11695"
                     /old_locus_tag="PQS91_11690"
     CDS             7413..8207
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010483441.1"
                     /locus_tag="PQS91_RS11695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_11690"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_109814026.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.2e-16, bitscore:
                     55.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTTLLAAALALAGVATPAFAAEADAGATPTVILVHGAFADGSS
                     WNKVITTLHDWKLPAVAVQNPLTSLADDVAATRRAIAAAPGKVVLVGHSWGGTVITEAG
                     NDPKVQALVYVAAFAPDAGQSSAQQGEGYPVGPGLTRLQEKDGYLTLPADAIAQDFAPD
                     VMKKTAALLYSTQVPLKASALGESVTVAAWRSKPSWYVLSRDDRMLSPQLQAATAKRIG
                     AQLQSIGSSHVSLLSHPAQVADSILEAAGVKPAELPLAEQGG"
     gene            8211..8756
                     /locus_tag="PQS91_RS11700"
                     /old_locus_tag="PQS91_11695"
     CDS             8211..8756
                     /GO_function="GO:0016209 - antioxidant activity [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005415663.1"
                     /locus_tag="PQS91_RS11700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_11695"
                     /product="redoxin domain-containing protein"
                     /protein_id="WP_010483439.1"
                     /transl_table=11
                     /translation="MGALRVYVLPLLLGLLGGAALLMALPSPEAGAHPAQAAPAAGFDG
                     GGPWHNSPPLALNQLRGQVVLVEFWTYACSNCLTVAPHVHQWHARYARQGLQVIGVHTP
                     EFAYEGLPGNVRKAIARLDITWPVVQDNQYRIWNAWGNRFWPALYLVDRQGRVVYRHYG
                     EGDYARTESEIQRLLASP"
     gene            8814..9554
                     /locus_tag="PQS91_RS11705"
                     /old_locus_tag="PQS91_11700"
     CDS             8814..9554
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659345.1"
                     /locus_tag="PQS91_RS11705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_11700"
                     /product="response regulator"
                     /protein_id="WP_272774118.1"
                     /transl_table=11
                     /translation="MNHVPHILVVDDDSEIRQMLADYLQRNGLRVSQADGGRAMRALMD
                     THAVDLVVLDVMMPGEDGLSLCRNLRAGKHRAVPVVLLTARDDETDRIIGLEMGADDYV
                     TKPFSSRELLARINAVIRRTLMLPPNLQVSEAGRQLAFGDWRLDTTARHLLDAQDTAYP
                     LSGAEFRLLRVFLDHANRVLSRDQLLSLTQGRDAELFDRSIDLLVSRVRQRLGDDAREP
                     TYIKTVRSEGYVFSVPVQLLGPEE"
ORIGIN
        1 ttcctgcact tctgcctcgg cctgggcgcg atcgtcgcgc tgctggtgct gtgcctgctg
       61 ttcctgcgcc atctgctgcg gctgctgaag tcggcggcgc gcgagcggcc gttcacccac
      121 gccaacgcgc agcgcctgca acgcatggcg tggttgatgc tggcgatgga gctgctgtcg
      181 atcctgatcg gcgcttacgc ggcctggatg gggcccgact tcacttggat ggaggtgggc
      241 ggcggcatgt cgatcaccgg cctggtggcg gtgctgatgc tgttcgtgct ggcgcgcgtg
      301 ttcgccgtgg gcgcagcgat gcgcgatgac ctcgatggtg tcatctgatg gcgattgtca
      361 tcaccctgga ccgcatgctg caggaacggg gcatgaccct gtccgagctg gccgggcgca
      421 tcgacatcac cctggccaat ctgtcgatcc tgaaaaccgg caaggcgcgt gccatccgct
      481 tttccaccct ggatgcgatc tgccgtgagc tgcagtgcac gcccggtgat ctgctcgggc
      541 atgacccgac gcaggcgcag gacgctgact gagtgctttc cctttttccc tacctactga
      601 cgaaacggac ctgaaatgga atggttggct gacccctcga tatggatggg ccttgcaacc
      661 ctggtcgtgc tggagatcgt tctcggcatc gacaacctgg tgttcatcgc gatccttgcc
      721 gacaagcttc cgccgcacca gcgtgaccgc gcgcgggtga tcggcctggc gctggccctg
      781 ctgatgcggc tggtgctgct ggccgcgctg gcctggatca tgaagctgac cgagccgctg
      841 ttgacgctgt tcgaccacag tttctccgga cgcgacctga tcctgctggg tggcggcctg
      901 ttcctgctgt tcaagggcac catggaactg catgagcggc tggaaggccg ccagcacgag
      961 gacaatggca agaaggtcta cgccagcttc gcgatggtcg tggcacagat cgtggtactc
     1021 gacgcggtgt tctcgctgga ctcggtgatc actgcggtcg gcatggtcga caacctgggc
     1081 gtgatgtacg ccgcggtgac catcgcgatg gcattgatgc tggtggccag caagccgctg
     1141 acccgcttcg tcaacaagca tcccacggtg gtggtgctgt gcctgggctt cctgctgatg
     1201 atcggtttca gcctggtggc cgagggcctg ggctacaaga tcccgaaggg ctacctgtac
     1261 gcggccatcg ctttctcgat cctggtcgag gcattcaacc agtgggtacg tttcaaccgc
     1321 gagcgcaacg agcgccgcca gccgttccgc caacgtactg cggatgcggt gctgcgcatg
     1381 ctgggcgcgc gcccgaccaa tggccacgac gacgaaagtg ctgacgaaca cgtcgatgcc
     1441 gaagagcgcc tgcagccggc cgagcacgag atgatccgca gcgtgctggg gctggcggat
     1501 cgcccggtgt cgagcgtgat gactgtgcgc gccgacgtgc agtggatcga cctggcgcgt
     1561 ggacaggacg acgtggtggc acgcctggtg gcatcgccgc acacccgcct gctggtcggc
     1621 gacggcgacc tggacagcct gcgaggcgtg gtgcagagcc gcgacctgct ggccgacctg
     1681 ctgcagggca agccgctgca gctggaaggc aacctgcgtg agccgcagta cgtgctgtcc
     1741 agcgccagtg cgctgcaggc gctggaactg atccgccagc acccggtgcc gctggcggtg
     1801 gcggtggacg agtacggcag cgtggaaggc ctggtgaccg ccaacgacct gttggcggcc
     1861 attgccggtg acctggtcga cacccaggac gagcgctatg gcgtggtcat gcagggggaa
     1921 ggccagtggg aggccgacgg tgcgctgacc ctggacgatc tgcagcgcct ggcgggcgta
     1981 tcgctgccgc gcagtgccga ctacatgacc atctccggcc tggtgctgga gcgcctggga
     2041 cgcctgccgg acatcggtga cgcagtggag atcgcggatg tacgcatcac cgtactggcg
     2101 atggagaagc gtcgcattgc ccgcctgcgc gtgcagcgcc tcgacggaat ggcctgaccc
     2161 gcctgttgat gtagagccga gcccatgctc ggctgcatgt tgagaagccg agcatgggct
     2221 cggctctaca caacacggcc cgcaaccgtc accatggcgg gcccgctttc tgtcatggat
     2281 ggttgcagtg ctgagtacga tcggtttgtt gatgggcctg tatgtggcct ggcgcctgtt
     2341 ctggccactg cgcatgccca cctggatgaa agtcgtgctg tcactgctgt tggtgggcgt
     2401 tgccgtgcag ctgcgcatcg tcgccatgtt ctggggcacg atggcctcgc ccgagattcc
     2461 gaaactggcc atcgccacgc tggccaccgg ctccacggcg gtgttgctgc tggcgttgct
     2521 gatgctggcg ctggacgtga gcctgcttgc ttcccgcctg ctgcgctggc cacgcgcggt
     2581 agccgcattg cgcacgcgga gtctgcgacc ggcggccggc ttgctggccc tgctggtcag
     2641 tggttatggc atcagccagg gcatggcggt gccccagcct cggcagatcg acgtggcgat
     2701 caaggatctg ccggccgcgt tcgacggcta tcgcgtgctg cagctgaccg acatccacgc
     2761 cagccgcctg ctgaccggtg actgggtgcg cagggtggtg gaccagagca acgcactgac
     2821 gccggacctg atcgtgatca ccggcgacct gatcgacggc agtgtcgagg cccgccgtga
     2881 cgacgcgcgt ccactcgtgg acctgcgggc gccggacggc gtcgtcgcca tcaccggcaa
     2941 ccacgagtat tacgcgcagt accaggcgtg gatgcaggcg tttcgcgcgc tgcacatgca
     3001 ggtgctggag aacagccaca tgcaggtgcg gcgtggcgat gcggcgctga ccatcgccgg
     3061 tgtcaccgac ccggtggcgg cacgctacgg cctgccgctg ccggatatgg acgctgcatt
     3121 ggctggcgcc gatccctccg cgccggtgat cctgctcgat catcgcccac gcaatgcgcg
     3181 tgaggccgct gcgcgcggtg tgaagctgca gttgtccggg catacccacg gcggccagat
     3241 catcggcatg gaccagctgg tgaagcgggc caacggtggc tatgtctccg ggcgttacga
     3301 ggtggacggg atgacactgt acgtgagcaa tggcgctggc ctgtgggccg gattccccgc
     3361 gcgcatcggc gtgccgtcgg agatcaccct gatcaccctg cgccgcgccc cgtgacctga
     3421 agtggggtca gatccctttc cgcagggaat tcgctgcctt tcgtgctggg atccctctgt
     3481 agagccgagc ccatgctcgg ctgaaccaga ggcagccgag catgggctcg gctctacagg
     3541 taaccgactc ctcaagaact ccgcagcggc ggccgcgcat gcgcattgcg ccgcagcgac
     3601 tgcgcccgct tggcgatcgc acgcaccacg acggcggtga agagcaacgc ggagggcacc
     3661 gcgtaccaga agttgccggg cacgcgcttg aagtacgaat aggtgaacac tgcggcgatg
     3721 atccacatgc cggtcacgtg caggcgacgc cacgcagtgg gacccatgcg gcgggcgatg
     3781 ccacgatgcg aggtgatggc cagggcgagg atggctacat agccgatcgt gcccggcagg
     3841 ttggccaggg ctgagcgcgc cggccagaac gcggggttga ggatgccgaa ggcggtgatc
     3901 gccaccgcat gcagcaggtg cgagaacgcg aacgacaggc cgacgatgcg gcgctcgcgc
     3961 agcaggaagc gggtgaacgg gccgggcagc aggctggcga acgaggatgc ggtgaaggcg
     4021 gccaggaaca gcaggaacga tgtgcgtgcc gtcacccgga tcgccgcgcg gctgccctcg
     4081 accacgtcgg gctgcagggt gaacgccgcc agtgcgaagg cgatcaggac cacggcgatg
     4141 gccacgaaca ggcgccagcc gtgcagggag gacgtattgg aaacagccat gatcaaacct
     4201 cgaatcagga aatgggtggc accggcctct ggccggccaa ggaatgcgga gtgccggccg
     4261 ctggccggcg ccttcaacag tcgttcggca caaccagcac gccggccgcg cacaggtcgc
     4321 ccagcagcgg aatgcaggct gtgcgtagtt cgtcggcggc cacgccatga agatcggcca
     4381 gtacctgcag cgcgtcttcc gcacgggcgc cgtcatcgcc gaacgccgac agcagcgcat
     4441 atgccagcgg tgaaagttcc tgcacctgca ggctgaagtc acccaggcgt cgcagcagca
     4501 gcaacgtcgg catcgtggta ggcgcaccgt tctggccggc gtcctcatgc acaggccact
     4561 ggtagcccag cacccgcacc agtggagaca gcgccagcac gctgcctgcc tgtggcgcat
     4621 gcaacggctg ctggccggtg tgccgcgctt caatgtgcag tgcctgctgc gtgctttcgt
     4681 aatgcgccag ttccgccacc cagcccggca gcgcgaggtc tgcctgcacg cccagccacg
     4741 cggcgaattc gccggcgatc tgcgggaaca acggggtatg gcaggcatgc cgcgcgtagt
     4801 agtgctccac ggtgtcgcgc cagcaggcat cacccagttg cgcctgcagg cgcggcaggc
     4861 tgcctgccag caggctgtcc aggctgtcga tgcagaggcg gcggtagacc gccatccgcc
     4921 gtgcatcgat gccctcaggc gcgggcatcg atgggtcgcg tacatggtcg gcccagcgct
     4981 gctgcagggt ggccagcggc tcagccatgg gccacctcgg gcggcagcac atcggcctgc
     5041 gcgtggcgga tctgctccac ctcggccagc agctcggcca aaggcgggaa gttgaaatcg
     5101 cgctccagca gggtggggcg cacgccgaca cgcgcatagg cctcccccag cagcgcccag
     5161 accacgccct tcaccggcgc gccgtgggtg tcgatcttga agccatcgtc ttcgtcgaag
     5221 tggccggcca cgtgcagcga ggcgacgcga tgcgccggca cgcgtgccag gaaatcgaag
     5281 gcgtcgtagc cgttgttgca ggcgttgacg aagacattgt tgacgtccag cagcaggtcg
     5341 cagtcggcct cggccagcac tgcagtgatg aattcgatct cgctcatgtc cgcgcctggc
     5401 acggcgtagt aggagatgtt ctccacggcg atgcgccggc ccagtgtgtc ctgcacctgg
     5461 cggatgcgac cggcaacgtg atgcacggcc tcggtggtga acggcagcgg cagcaggtca
     5521 tagacatggc cgccggcggc gcagtagctc aggtgttcgc tgtacagctg cacctggtgc
     5581 aggtcgagga acgcgcgggt ctgcgccagc agggtgcggt ccagcgggtc cggccctccc
     5641 agcgacagcg acaggccgtg gcaggtcagg cggtggcgct cactcagctg gcgcagcgcg
     5701 gcgccgtggg caccgccaac tccgatccag ttgtccggcg acacttcgag gaagtcgatg
     5761 gcatcggccg gcatcgccag cagttcatcg atcaggccac ggcgcaggcc gagaccggca
     5821 ctggcggaag gcaggggtaa gcgcatgcga cggtactcca gggcagtggc gccgccgtgg
     5881 cggcgccggg gggaacgatc agtcgttgac gcgggagaac aggcccttcg gcatcggttt
     5941 gccgttggcg gtgtagacac tgcgcaggta gtcgtgcgcc tcctgttcgc tgatgtagcc
     6001 gtcgtggtcg gtgtcgatgc ggtcgaattc agcggcgcgc ttggccgcca cggcgttgaa
     6061 ctcggcacgc gagacccggc cgtcgtggtc acggtcggtg cgggcaaacg aagcgtcgcc
     6121 gcacttgcct tcgccacact ggccttcggc caccttggcc ttggcggcag gcttgccagt
     6181 ggcggccttg ttggcgccgc acttgccttc accgcacttg ccttcggcgg cggcgctcat
     6241 ggccacggca ccgatggcca gtggctggat cgcggccgcc tggccggcca gcagcaggcc
     6301 accggccagg gcgatgccga tggcgccgat gcgcggcaga cgggaagcag cggtgttctt
     6361 ggtcgagacg gacatggtga tgactccttg gatgggcacg cagggcgtgc gggatggacg
     6421 ccgcttgaag gcgacggaaa cgaagggaag aagcgcggga agcggtgaag cggatcaggc
     6481 gttgcggcga cggcgcagtc ggtaacccag cagcagggcg ccgccgagta gtgcgccacc
     6541 gaaaccgata ccgggcagca gcgcggcgac cggcagcagc agggcgatca ggctcacgcc
     6601 ccagccgagg ccgtcgttgc ccgccgcggc gcgctgcggg ccggccagca ggcggtccag
     6661 gctgagtgca ccgccgccgt tgaggatcag cggcagcagc atggccagga acagcagcgg
     6721 cagcttgaag ttgccgtagc cctggtcggt gattgcgtag ccctgccaca gctcacccag
     6781 gctgttccat tggtccggcc agtgcacggc agcgatggca acaagggtca gcacccagaa
     6841 gatgtaggcc accgagcgcg tggccaggcc cagcagcagc atcaccgcgc ccaccagttc
     6901 cagccaggtg gccagctgcc agttgagtga cgcaggcagg gtggagaacg ggaacgggaa
     6961 acgcccttcc aggtcggcga accagttctg tccgcccagc ttctcgcggc ccgattcaaa
     7021 gaactcccag gccagcaggg cgcgcagcgc caatggcgag agccagcggc cgacggcgtc
     7081 caggcggggt gtatacacgg aagaagcgga gctgatcatg ggagtgtcct gcgggccagt
     7141 ggtcgatgga ggccattccg agccacgcag gtatcggcaa cgtgtgctgt tgcccggggt
     7201 tttgtcagcg actgtggctg tgtcaggggt tcgtacagtc agatacaaag acgccgcgtc
     7261 gggcgttcgc cgggccatgc ccagcggccg aatgtatcca actgtagaaa tctgccgccg
     7321 ccctacagtc cggtacaact ctgcctcgca gcgaaacagc gccgatacac ccccaggcgg
     7381 aaatggccac tcccaacacc ggagtgccac ccatgatccg caccaccctg ctcgccgctg
     7441 ccctcgccct tgccggcgtc gcgacgccgg cattcgccgc cgaggccgat gccggcgcca
     7501 cgcccaccgt catcctggtc cacggtgcct tcgccgatgg ctccagctgg aacaaggtca
     7561 tcaccaccct gcatgactgg aaactgcctg cggtggccgt gcagaacccg ctcacctcgc
     7621 tggccgacga tgtggccgcc acccgtcgcg cgattgccgc cgcaccgggc aaggtcgtgc
     7681 tggtcggcca cagctggggc ggcacggtca tcaccgaagc gggcaacgat cccaaggtgc
     7741 aggcgctggt gtacgtggcc gcattcgcac cggatgccgg gcagtcatcg gcacagcagg
     7801 gcgagggcta tccggtcggc ccgggcctga cgcgcctgca ggagaaggac ggctacctga
     7861 ccctgccagc cgacgccatc gcccaggact tcgcaccgga tgtgatgaag aagaccgctg
     7921 cactgttgta cagcacgcag gtgccattga aggccagcgc gctgggtgag tccgtcactg
     7981 tggccgcgtg gcgcagcaag ccgagctggt acgtgctcag ccgtgacgac cgcatgttgt
     8041 cgccgcaact gcaggcggcc accgcaaagc gcattggcgc gcagctgcaa tcgatcggca
     8101 gcagccatgt gtcgctgctc tcgcacccgg ctcaggtggc tgacagcatt ctggaagccg
     8161 caggcgtgaa gccggccgaa ctgccgctgg ccgagcaggg aggctgaacg atgggcgcgc
     8221 tgcgtgtgta tgtactgccg ttgctgctgg gcctgctggg tggggcggcg ctgctgatgg
     8281 ccttgcccag cccggaggcc ggtgcgcatc cggcgcaggc cgctcctgct gccgggttcg
     8341 atggcggcgg gccctggcac aacagcccac cgctcgcgtt gaatcaactg cgtgggcagg
     8401 tggtgctggt cgagttctgg acctacgcct gcagcaactg cctcaccgtg gcaccgcatg
     8461 tgcaccagtg gcatgcacgt tacgcgcggc aggggctgca ggtgatcggc gtgcatactc
     8521 cggagttcgc ctacgaaggc ctgcccggca atgtgcgcaa ggccatcgcg cggctggata
     8581 tcacctggcc ggtggtgcag gacaaccagt accggatctg gaacgcctgg ggcaaccgct
     8641 tctggccggc gctttacctg gtcgaccggc agggcagggt ggtctaccgc cactacggtg
     8701 aaggcgacta cgcacgtacc gagagcgaga tccagcgcct gctggccagc ccctgagccg
     8761 cgctaccatg gccgcgccgc gcggccttga cctccgtctt catcgagaac gcaatgaacc
     8821 acgtaccgca catccttgtc gtcgacgatg acagcgagat ccgccagatg ctggccgact
     8881 acctgcagcg caacggcctg cgcgtcagcc aggccgatgg cggccgtgcg atgcgcgcgc
     8941 tgatggacac ccacgcggtg gacctggtgg tgctggacgt gatgatgccc ggcgaggacg
     9001 ggttgagcct gtgccgcaac ctgcgtgccg gcaagcatcg cgcggtgccg gtggtgctgc
     9061 tgaccgcccg cgacgacgaa accgaccgca tcatcggcct tgaaatgggc gccgatgact
     9121 acgtgaccaa gccgttctcc tcacgcgaac tgctggcgcg catcaatgcg gtgatccggc
     9181 gcacgctgat gctgccgccg aacctgcagg tgagtgaagc cggccgccag ttggccttcg
     9241 gcgactggcg cttggatacc actgcccgcc atctgctgga tgcgcaggac accgcctatc
     9301 cgctcagcgg tgcggaattc cgactgctgc gcgtgtttct cgaccacgcc aaccgtgtgc
     9361 tcagccgcga ccagctgctc agccttaccc agggccgtga tgcagaactg ttcgatcgtt
     9421 ccatcgatct cctggtcagc cgcgtgcgcc agcgcctggg cgatgacgcg cgtgagccca
     9481 cctacatcaa gaccgtgcgc agcgaaggct acgtgttcag cgtgccggtg cagctgctgg
     9541 ggccggagga atgaacgccc gcgcgcgccg cctgccgtgg ccgcgcacgc tgtcggcgcg
     9601 cctgctgctg gtgctgctgg gcggtttgat cctggcccat gcgctgtcct tcggcctgtt
     9661 gttctacgaa cgctaccagt ccacccgcag catgatgctg cgcaacctgg acgaggatgc
     9721 agcagtgagc gtggccctgc tggaacacct gccggccgac cagcgccagg cctgggtgcc
     9781 gcggttggag cggcgcacgt accgttacct gttgcgcccg gcacaggccg gcccggcgtt
     9841 ggaaaccgat cgtgcgcgcc aggtcaccgc catcatcgat gacagtctgg aacaccgcta
     9901 tccgctgcag gcgcggcagg tggcacggct gccggaacgt tttgaagtgg agctgcgcct
     9961 gcacgacggt tcaccgttga ccatcgaagt cacaccgtcg ggcctgccgc tggcgcgctg
    10021 gctgccggcc gtgctgctgg tgcagctggc cctgctgctg gtatgcgcct ggctggcggt
    10081 gcggctggca ttgcgcccgc tgcggcagct ctcgcacgcc gtcgagcaac tgcagcctgg
    10141 caaggacgca ccgatgctgc ccgaagacgg ccccgccgaa gtgggcacgg ccgcagccgc
    10201 gctcaatgca ctgcaggcgc ggatccgtgg ccatgtcagc gagcggctgc agattctggc
    10261 ggccatctcg cacgatctgc agacgccgat cacgcgcatg aagctgcgcg tggaaaccct
    10321 gcccgaagat gccacccagc agcgcctgct ggatgacctg gaccacctgg ggcaactggt
    10381 gcgcgaaggc gtggcctacg cgcgcagcag ccacgtggcc agtggcgcgc cagtggcgat
    10441 ggatcttggc gcgttcctgg ccagcgtggt gggcgactat gaagacatgg gcaaggcggt
    10501 cagtggtggc gcacccacag gcctgaccgt gcagacctgg ccgcagccgc tgcggcgggt
    10561 ggtcggcaac ctggtcgaca acgcgttgcg ctacgccggt agtgccgaga tcgaggcggg
    10621 gcgcgatgca gcaggccggc cgtggatcag cgtgtccgac cgcggccccg gcatcccgga
    10681 ggaccagctg caggcggtgc tggcaccgtt ccatcggctg gaaagctcac gcaaccgcga
    10741 taccggcggc accgggctgg gtctggccat cgccgtgcag ctggcgcagt cgctgggcgg
    10801 ctcgctgcgg ctgcacaacc gtgagggcgg tggcctgcgg gccgaa
//
