LOCUS       NZ_JAQQGI010000001     20879 bp    DNA     linear   CON 12-MAY-2024
DEFINITION  Stenotrophomonas geniculata strain BLCC-B124
            NODE_1_length_1175979_cov_208.540449, whole genome shotgun sequence.
ACCESSION   NZ_JAQQGI010000001
VERSION     NZ_JAQQGI010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Stenotrophomonas geniculata
  ORGANISM  Stenotrophomonas geniculata
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas.
REFERENCE   1  (bases 1 to 1175979)
  AUTHORS   Lefler,F.W., Fernando,B., Fernando,A., Berthold,D.E., Kennedy,A.,
            Indest,K.J. and Laughinghouse,H.D. IV.
  TITLE     Draft genome sequences of cyanocidal bacteria isolated from
            cyanobacterial infested fresh waters
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1175979)
  AUTHORS   Lefler,F.W., Fernando,B., Fernando,A., Berthold,D.E., Kennedy,A.,
            Indest,K.J. and Laughinghouse,H.D. IV.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-FEB-2023) IFAS, University of Florida, 3205 College
            Ave, Davie, FL 33314, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-JAN-2023
            Assembly Method                   :: SPAdes v. 3.15.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 431x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_028550615.1-RS_2024_05_12
            Annotation Date                   :: 05/12/2024 16:37:49
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,164
            CDSs (total)                      :: 4,091
            Genes (coding)                    :: 4,068
            CDSs (with protein)               :: 4,068
            Genes (RNA)                       :: 73
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 65
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 23
            CDSs (without protein)            :: 23
            Pseudo Genes (ambiguous residues) :: 0 of 23
            Pseudo Genes (frameshifted)       :: 2 of 23
            Pseudo Genes (incomplete)         :: 19 of 23
            Pseudo Genes (internal stop)      :: 4 of 23
            Pseudo Genes (multiple problems)  :: 1 of 23
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:51:48
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1072572
            Orig. end                         :: 1093451
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAQQGI010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20879
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="3"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20879
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20879
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10879](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10879
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(56..70)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.2"
                     /tool="antismash"
     gene            complement(496..1740)
                     /locus_tag="PQS91_RS04955"
                     /old_locus_tag="PQS91_04955"
     CDS             complement(496..1740)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005410514.1"
                     /locus_tag="PQS91_RS04955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_04955"
                     /product="DUF418 domain-containing protein"
                     /protein_id="WP_049409182.1"
                     /transl_table=11
                     /translation="MADLPDGCPVNAASPSLQPMASGERIAILDVLRGAALLGILLMNI
                     EAFSGPLDLAFTGIDVHWQGIDYWADAFVYVFVQGKFFTLFSLLFGAGFAVMAQRAEAA
                     GRDFTPFYLRRSAGLLLIGLCHALLVWSGDILVMYALVSLPLLACREAPRSWLPWMGVT
                     VYLGGIAMMLLVGAMVSMASTEDVQKMLADAQQSIELQRLVYGHGSWMQANAQRLSEFG
                     TSMGALLITGPEVLGMFLIGSWFAGSGALAAPERFPRLYATLRWIALPLGLLVTLIGVA
                     WKPYLAPGAYNLPVTTAMALVTIGGLPMCLGYLAWIVHWRARLAWLAPVGRMALTHYLG
                     QSLLCTWLFYHYGLGAFEMMPRSVQLLFALLLFAVQVALSHVWLRRFRFGPMEWLWRAM
                     TYRQWPPMRREAGQG"
     gene            complement(1840..2322)
                     /locus_tag="PQS91_RS04960"
                     /old_locus_tag="PQS91_04960"
     CDS             complement(1840..2322)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010482989.1"
                     /locus_tag="PQS91_RS04960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_04960"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_010482989.1"
                     /transl_table=11
                     /translation="MKIEKDRVVRFHYTVSEVGQEPIESSKDRGEPLAILIGHGNIIPG
                     LENAMMDKEAGATFSVDVTAADAYGERREGLSQRVPKKHFGNTKLAPGQQVVLQTNFGP
                     RAVTVQKVGMSVVDVDLNHPMAGKDLHFDVEIVDVREAGKEEIDHGHVHGDGGHHH"
     gene            2434..2973
                     /locus_tag="PQS91_RS04965"
                     /old_locus_tag="PQS91_04965"
     CDS             2434..2973
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014038010.1"
                     /locus_tag="PQS91_RS04965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_04965"
                     /product="C40 family peptidase"
                     /protein_id="WP_026347086.1"
                     /transl_table=11
                     /translation="MHITPVSSGQRRFLAPALLLALPLLMTACGGGKATRPAPPPPTAN
                     WPKTVPDNPEAANSVLMRAISLVGTPYRYGGNTPDSGFDCSGLVAYVYREMLDLRLPRT
                     SRDLAAVQGPKIDPQRLATGDLVFFGSRGSVTHVGIYVGEGRFVHAPSTGGTVRLDSLS
                     GPYWKDHYTGAKRVLR"
     misc_feature    complement(2999..3014)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     misc_feature    3082..3091
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.63"
                     /tool="antismash"
     misc_feature    complement(3094..3109)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            3105..3878
                     /locus_tag="PQS91_RS04970"
                     /old_locus_tag="PQS91_04970"
     CDS             3105..3878
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266333.1"
                     /locus_tag="PQS91_RS04970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_04970"
                     /product="C40 family peptidase"
                     /protein_id="WP_053092540.1"
                     /transl_table=11
                     /translation="MTTDDLKSEGQTSVSSRSARPLLLGLALCLTSLPAWSQTAPNRFD
                     VTPAPVAESTARPATKAEAAAPQRSRVDAAASATLAALLPHLAANDTIPLMDRSAVVAG
                     DLSRLLANYDTSSAANGSVVGTAADNGKVQSLLRRAMTLLGTPYRWGGSNPDSGFDCSG
                     LVGYVFRSALGIELPRVSREMAHDDNAELINDRTALAAGDLVFFGRKGRVDHVGIYVGD
                     GRFLHAPSSGKDVRVDTLLSGYWGNKFMQARRVDL"
     gene            complement(4138..5472)
                     /locus_tag="PQS91_RS04975"
                     /old_locus_tag="PQS91_04975"
     CDS             complement(4138..5472)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1212:
                     sodium:dicarboxylate symporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019660634.1"
                     /locus_tag="PQS91_RS04975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_04975"
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="WP_019338617.1"
                     /transl_table=11
                     /translation="MKLVSAWLRIPFWQRVVGGFVLGALAGWALGPAAETWFGPLGELY
                     VTLIKMIAVPLVFFAVINAISSLHGQKSVAALSGRTFLWFVITAALAVCVGLGVGTVLQ
                     PGAGGLQLTMASNYVPREVPSVVQVLLDVVPANVFYALSGIGTKVNAAGETVLAAGRGS
                     ILPVIFFAGLVGFAIVKLGEKVTEARKLVGQMSDIMIQVTRFVLEVTPIGTFGLIAGLV
                     GSYGFEKLLPLGHFVLALYVACALHIVVVYSALLLAHGLNPLKFFRGAAPGMQVAFVSS
                     SSFAAMPVALRSITHNLGVNKDYGSFAVPLGASIKMDGCGAIYPALCAVFISQYSGVPL
                     TPEQYVVVLIASVLGSFGTAGVPGTAVIMATVVLSAANLPLETIGYLYAIDRILDMMRT
                     MTNVTGQMLVPVIVAKETGLLDQAVYDNPSSNVGVDDPDPTPPRA"
     gene            5627..7333
                     /locus_tag="PQS91_RS04980"
                     /old_locus_tag="PQS91_04980"
     CDS             5627..7333
                     /EC_number="3.1.3.1"
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019660635.1"
                     /locus_tag="PQS91_RS04980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_04980"
                     /product="alkaline phosphatase"
                     /protein_id="WP_197576898.1"
                     /transl_table=11
                     /translation="MRRSVSLLAACATTLLLGACASTAPASAPAGLKVAVDPVTHPAGE
                     TPQWWYRSGAAQAAANGAMSGKARNVILFLGDGMSLTTVAASRIYEGQQKGGSGEENLL
                     SWERFPATAFSKTYNTDSQTPDSAGTMTAITTGVKTHMGAIGVSAGSRTDCADSLSKGL
                     LTWLQLADSAGLATGVVSTARLTHATPAATYAHSPERNWENDTDLTEAAKAAGCKDIAQ
                     QLLSTSRYGRGPLVALGGGRGEFTTVEERDPEYDDKVGQRLDGRSLVQEWQQAHPQGAY
                     VWNSKQLAAAANAPAILGLFEPDHMRYEYERPQDPGGEPSLAELTAAAIRNLSKHREGY
                     VLMIEGARIDHANHSGNAYRALTETVALSDAVRVANELTSADDTLIIVTADHSHTLNFV
                     GYPARGNPILGKVKDKGGEDGAGKLDYALDGTGQPYTTLSYANGPGHTGSSNQQPAGPK
                     RYPHNPSSFEPANGRPNLREVDTEHPDYMQEALVPMKSESHGGEDVGIWARGPGSKAIR
                     GTLEQNAIYHMIVQATPALRERLCQAGTCDDKGVPVQLPAPTAFERKAEAK"
     gene            7330..7875
                     /locus_tag="PQS91_RS04985"
                     /old_locus_tag="PQS91_04985"
     CDS             7330..7875
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019660636.1"
                     /locus_tag="PQS91_RS04985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_04985"
                     /product="WG repeat-containing protein"
                     /protein_id="WP_010482979.1"
                     /transl_table=11
                     /translation="MIALQARPAPASGRFARSLALLGVLASANALAQAPACKLLTDEHG
                     LWPLPNCEVVDHRPKIQPDTLKDLNFDDHGLAVVYADQGFHYVDRKGRSLPVLTWDNGP
                     EMPEEGLLRGRVGNRVGYFDLTFRQVVPGTFDFAWPFRDGVAEVCNGCRRGTPDADGHT
                     PMEGGEWFRIDRSGRRVK"
     gene            8428..9714
                     /gene="tilS"
                     /locus_tag="PQS91_RS04990"
                     /old_locus_tag="PQS91_04990"
     CDS             8428..9714
                     /EC_number="6.3.4.19"
                     /GO_function="GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="tilS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005418067.1"
                     /locus_tag="PQS91_RS04990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_04990"
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="WP_272773821.1"
                     /transl_table=11
                     /translation="MTAFPALVPLDAPLLVGYSGGVDSTVLLHWLWRCAQASGTALRAV
                     HVHHGLQPAADDWVRHCQQQCAALGVELAVRHVQIDRTTGLGLEGAAREARRAAFTAEL
                     REGETLALAQHQDDQAETFLLRALRGSGVDGLAAMADDSQLGTHRLWRPLLHAPRTALL
                     DYARQHALRWIEDPSNAEDHADRNFLRLQVLPLLRQRWPHAAAALAGSVLHCRQTRELL
                     DEEDAELITHLEVAPRVLSLQLLRQVSPGRAARVLRAWVIGHGAAPLPATVLQQGLDEL
                     LPVGNDRQARVRWHDHAIQQWREHAYLLPAQLPSLPRAWQAEWDGHAPLPLPDGGQLRL
                     QGGAAFERPLQVRARLGGERILLPGRQHSHALKDCLQREHLAPWRRAQLPLIFDGPQLL
                     AAADVVISAPLQAWLQAHQAQLQWRPGGW"
     gene            9751..10011
                     /locus_tag="PQS91_RS04995"
                     /old_locus_tag="PQS91_04995"
     CDS             9751..10011
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005410522.1"
                     /locus_tag="PQS91_RS04995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_04995"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_019338620.1"
                     /transl_table=11
                     /translation="MAKKSPENASPVAQFEQSLESLEQLVEQMETGELSLEASLSAYER
                     GVGLYRQCQQALEQAELRVRLLSDPAQPEASEPFDPPNHDG"
     gene            10001..10879
                     /locus_tag="PQS91_RS05000"
                     /old_locus_tag="PQS91_05000"
     CDS             10001..10879
                     /EC_number="2.5.1.10"
                     /GO_function="GO:0004337 - geranyltranstransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264747.1"
                     /locus_tag="PQS91_RS05000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_05000"
                     /product="farnesyl diphosphate synthase"
                     /protein_id="WP_019338621.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.6e-65, bitscore:
                     217.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAEVLFARWRDRIESQLDAALPSPAEAPQRLHQAMRYSVLGGGK
                     RMRPLLVYASGHLFGAQLESLDAAAMSVELIHAYSLVHDDLPAMDDDALRRGKPTTHIA
                     FDEATAILAGDALQTRAFGLLADAPLPATLRVACLQTLAHASGASGMCGGQALDIDATG
                     QQQTLAALTRMHALKTGALIRAAVRMGALCGQAHEPQLAQLDSFADALGLAFQVRDDIL
                     DVEASSEQLGKTAGKDQAQDKSTFPALLGMDGAKAQLHELAARMQSILAGYGEEADALR
                     ALATLAVERDH"
     gene            complement(10965..11336)
                     /locus_tag="PQS91_RS05005"
                     /old_locus_tag="PQS91_05005"
     CDS             complement(10965..11336)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014647933.1"
                     /locus_tag="PQS91_RS05005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_05005"
                     /product="DUF4870 domain-containing protein"
                     /protein_id="WP_010482972.1"
                     /transl_table=11
                     /translation="MSEFDNVPPPPATTDVPADQRTMALAAHLLGIFTGFIGALIIWLI
                     NKDDAGKAFVTDQAKEALNFQITVTIAMVISMILTIVIIGVFLAPIVGIISLVFSIIAA
                     VKANNGEAYRYPFALRLIK"
     gene            complement(11424..12791)
                     /gene="pmbA"
                     /locus_tag="PQS91_RS05010"
                     /old_locus_tag="PQS91_05010"
     CDS             complement(11424..12791)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="pmbA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019662101.1"
                     /locus_tag="PQS91_RS05010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_05010"
                     /product="metalloprotease PmbA"
                     /protein_id="WP_272773822.1"
                     /transl_table=11
                     /translation="MNVIAPEVAVGDDSPARLERLADLSQQLLDRARALGASQAEVSCS
                     EDRGLEVNVRLGEVETVQSTRDRGIAVTVYFGQRKGSASTGDLNEASLTATVEQACAIA
                     RHTEDDPAAGLAEAALMATDFPDLDSWHPWALQADEAVDLALACENAGREADAQIRNSD
                     GASVSSMQSLSVYANSHGFFGRERGTHHSVGCALIAGQGDGMQRDGWYTSALAREDLEE
                     VGLVGRRAAERTVARLQPRSMATGSMPVLFAPEVARSLVGHLLSAVSGGALYRHASFLL
                     DSVGQQLFPDWMQIEELPHLRRGLRSAAFDGDGVATRASALVRDGVLQRYVLGSYSARK
                     LGLQTTANAGGVHNLQLAANAGSLQEIARQMGDGLLVTELMGQGVNGVTGDYSRGAGGF
                     RVENGEIQYPVDGITIAGNLREMFSSIEAVGSDVDPRSHIRTGSILLGRMTIAGND"
     gene            12859..13446
                     /gene="yjgA"
                     /locus_tag="PQS91_RS05015"
                     /old_locus_tag="PQS91_05015"
     CDS             12859..13446
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yjgA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017355121.1"
                     /locus_tag="PQS91_RS05015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_05015"
                     /product="ribosome biogenesis factor YjgA"
                     /protein_id="WP_010482967.1"
                     /transl_table=11
                     /translation="MRGRDEETGEFHDKSRSQNRRDALDVLALGEKLVSLTPAQLARLP
                     IPEDLLPHIAECKRITAHIAHKRQLAFLAKHMRREEDATLDAIRDALDANSETGRREVA
                     MMHRAEDWRERLLAEGDKALAALLDDYPQADRQQLRTLVRNAQAEKAKNKPPRAYREIF
                     QVLRALMLPAALGLKASAEDADPIETDEADED"
     gene            complement(13488..14933)
                     /gene="tldD"
                     /locus_tag="PQS91_RS05020"
                     /old_locus_tag="PQS91_05020"
     CDS             complement(13488..14933)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="tldD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007972594.1"
                     /locus_tag="PQS91_RS05020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_05020"
                     /product="metalloprotease TldD"
                     /protein_id="WP_010482965.1"
                     /transl_table=11
                     /translation="MTDIALTLAQDRLLRPGGLDTAGLEHTFGQLLGPGVDFGDLYFQH
                     ARRESWSVEDGIVKDGAHSIEQGVGVRAISGEKTGFAYSDDIHADALRVAAQSARAISR
                     EGGAQTGRSLLRGNARALYPALDPIDGVGNEAKVEVLKRLDGYLRAADPRVKQVMVSLS
                     GGVDTVLIARSDGVLGADVRPLVRLNVQVIVEHNGRRESGYAGGGGRYGYEELFADGRP
                     EAFAREALRQALVNLEAVPAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYA
                     GRIGERVAAPGVTIVDDGTLDGRRGSLNIDDEGHPSQCTTLIEDGILVGYMQDSLNARL
                     MGVAPTGNGRRESFAHMTMPRMTNTYMRAGQHDPQEMIRSVKKGLYAVNFGGGQVDITS
                     GKYVFSATEAYLIEDGRITTPVKGATLIGNGPETMQKVRMVGNDLALDEGVGICGKDGQ
                     SVPVGVGQPSLLIEGITVGGTQA"
     misc_feature    14929..14943
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     misc_feature    14936..14950
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.56"
                     /tool="antismash"
     gene            complement(14994..18836)
                     /locus_tag="PQS91_RS05025"
                     /old_locus_tag="PQS91_05025"
     CDS             complement(14994..18836)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014647937.1"
                     /locus_tag="PQS91_RS05025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_05025"
                     /product="YhdP family protein"
                     /protein_id="WP_272773823.1"
                     /transl_table=11
                     /translation="MSAPPRLRLRRIRRHFIAACAVGLVGLALLVGTLSQLLPLAERHP
                     DRIAAWLSERAGQPVRFDQLQTAWTRRGPLLQLKGLRIGAGQGLAIGEAEVLVSMYSGL
                     LPGRSLTELRLRGLALDLQQGEDGRWSVRGLPQAANGGDPLDALRRLGELQVIGGRLGV
                     HAPGLGIDTTLPRIDVRLRVNGDRLRVGVRAWAQTEALPLTAVLDVDRVRGNGQAWLGA
                     DPVDFHAWSPLLAAGGVRLREGKGELNLWLTLRDFAPVAVTTDSDLRDVRIDGAPMPAM
                     AAPQLQLQRLQARLRWQRQADGWALQVPRLRLKTEEGEQQLDGLQLQLGKQLRVSSREV
                     QAGIALRALALSDRLEPGLRRWLFLSRPQLDVRELQLAGERDGPLWAQGELQSLGFASV
                     GNSPGLRGLGGRFEGDADGFSLQLQPQRQLQFDWPTGFGVRHDLHLAGQVVGWRDEGGG
                     WRIGTAAMRVEGTDYAADVRGGVWFQGDGTRPWLQLAAKLDDVPMTAAKRFWIHSKMSK
                     GATDWLDMALAGGQVRNGIGLVSGDLDDWPFDNNDGRFEATGHITNGDIRFQHDWPLMR
                     QVDADIAFIGPGFDMHGRGDLAGVAVQKFEAGIQDFGQQPLYVRADAQSEAGRLLAMLR
                     QSPLHKDYGDTLDNLTAAGPAHVTFDLLQPLHHDEGGGHLQGTVDLAGVKLVDKRFQLT
                     FDNMHGQARYSNGGFGAEELAVRHLGQDGRLSLRAGGYVHDSKLAFESQLSANLDAGVL
                     IDRAPEMAWLKPYIAGTSPWTIAVNLPKVAPGAPAPPSELRLSSDLVGTRLDLPAPLDK
                     PAAEPLATTVAAQLPMGAGRIDVAFGQRLALAARSHNNQTGVQVTLGSDHADREPPPSG
                     LSVNGRSPTLDALEWIGLARGGNDDDGMPLRAVDVQVGKLMLIGGVFEQTRLQLRPGAQ
                     ALDVRLDGPSLAGRLTVPNADGGTISGQLDRVHWQSLPAAPGVPAAPARVQAGANDMDP
                     AKLPPFALDIADLKFGKVVLGQAVLRTRPLANGLNVDELRFRAPDQEIDISGRWLGRSG
                     GARTELTAQVRSEDLGGLMQNLDYGGQLRGGSGQAQLQATWSGGPSDFQLGNLQGRLDL
                     HARNGQLLELEPGAGRVLGLLSVTQLPRRLMFDFRDFFSKGFAFNQIDGSMQFGQGMAR
                     TDKVLIEGPAANITIRGQADLRNQQFDQTIDVNPRAGNLLTVVGAVAGGPVGAALGAAT
                     NAVLSKPLGEIGARTYKVTGPWKEPKVEVIERSREKAPAPAPAIPPTVTGLPRSR"
     gene            complement(18867..20354)
                     /gene="rng"
                     /locus_tag="PQS91_RS05030"
                     /old_locus_tag="PQS91_05030"
     CDS             complement(18867..20354)
                     /EC_number="3.1.26.-"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="rng"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002802933.1"
                     /locus_tag="PQS91_RS05030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PQS91_05030"
                     /product="ribonuclease G"
                     /protein_id="WP_010482960.1"
                     /transl_table=11
                     /translation="MSEEILVNVTPRETRVAVIENGMLQELHIERGWRRGVVGNIYKGK
                     VQRVMPGMQAAFVEVGLERAAFLHANDVVRPAPVASADTENTTLPPPSSVPIVELLRDG
                     QDIVVQVVKDPIGTKGARLTTQISIPSRYMVLLPQSKVVGVSARIEDETERARLKALVT
                     ELSAQHGGYGYIVRTNAEGQPAEAIAEDIAYLSRVWNVVERRGREAASCSNIYEDLSLP
                     LRSVRDLIRKDVDKVKVDSKETFAQLQAFVAKYMPVLAEKIELYSGDRPIFDMFGVEDE
                     IGRALDKQVPLKSGGYLVIDQTEAMTTIDVNTGSFLGQRNLEETVFRTNLEAAQAVARQ
                     LRLRNLGGIIIIDFIDMDDAEHRRQVLRTLEKALARDHAKTTVYDFSPLGLVEMTRKRT
                     VESLERQLSETCPQCSGRGSIKTTETVTYEIFREITRAVRQFDAARLLVIASTKVVARI
                     TDEESAAVAELEEFLGKSIRFQADEQYLQEQFDVVLL"
ORIGIN
        1 ctgcgcgttc agcgcctcac actcggctgc atggtgatcg aaattgcggg cgtcaccgaa
       61 cacatagtcc agaccgcgcg cctcgaactc gcagtccagc gcatgcgtcc gcacccactg
      121 cgccaggcgc agccgtgaat cattcaacag tgcgccgcgt gcccgcgtgg agtgcagcca
      181 gtcacgcgcg ttgcagcgcg ccccgaactg cagcagccag cgccacaatg cagggtccag
      241 gcgtgtacgg acgtacagcg gcgcacgcgg atcgagcatc cagcgcagcg cccgtaacgg
      301 cacaccaggc gctgccagcg gtggcgcgtg gctgggggtg atggtgccgc agttgccatg
      361 cgaagtcgcc gcacccacgc gtccccgctc gatcatacgg acctgccggc cgttcgcgca
      421 cagcgcaagc gcggtggcca ggccgatggc accggcgccc accacgatca catcctcgcg
      481 cgcgccctgc atcgatcagc cctgcccggc ctcgcgccgc atcggcggcc actgccggta
      541 ggtcatcgcg cgccacaacc attccatcgg gccaaagcgg aagcggcgca accagacgtg
      601 tgaaagggcc acctgcacgg caaacaacag cagtgcgaac agcagctgca cgctgcgtgg
      661 catcatttcg aacgcgccca ggccgtagtg gtagaacaac caggtgcaca gcagcgactg
      721 gcccaggtag tgggtcaacg ccatgcgccc gaccggtgcc agccaggcca accgcgcacg
      781 ccaatgcacg atccacgcca ggtagcccag gcacatcggc aggccaccga tcgtcaccag
      841 tgccattgcg gttgtcaccg gcagattgta ggcacccggt gccaggtagg gtttccaggc
      901 aacaccgatc aacgtgacca gcaggcccaa cggcaacgca atccagcgca gcgtcgcgta
      961 caggcgcggg aagcgctccg gtgccgccag cgcgccactg ccggcaaacc agctgccgat
     1021 caggaacatg cccagcacct ccgggccggt gatcagcagc gcgcccatcg acgtgccgaa
     1081 ctcgctcagc cgctgcgcat tggcctgcat ccagctgccg tgcccgtaca ccaggcgctg
     1141 cagctcgatg ctctgctgcg cgtcggcgag catcttctgt acgtcttccg tcgaagccat
     1201 cgacaccatc gcgcccacca gcagcatcat cgctataccg ccgaggtaga ccgtcacgcc
     1261 catccacggc aaccagctgc gcggcgcctc gcggcaggcc agcagcggca acgagaccag
     1321 cgcgtacatc accaggatgt cgccggacca gaccagcagt gcgtggcaca ggccgatcag
     1381 caacaggcca gcgctgcggc gcaggtagaa cggggtgaag tcgcgcccgg cggcctcggc
     1441 gcgctgcgcc atcaccgcga agccggcgcc gaacagcagc gagaacaggg tgaagaactt
     1501 gccctgcacg aacacgtaca caaaggcatc ggcccagtag tcgatgccct gccagtgcac
     1561 gtcgatgcca gtgaaagcca ggtccagcgg tccgctgaag gcctcgatgt tcatcagcag
     1621 gatgcccagc aacgccgcac cgcgcagcac gtccagtatg gcgatgcgtt cgccggaagc
     1681 catcggctgc agggaaggag aagcggcgtt cacggggcat ccgtcaggca ggtccgccat
     1741 tatgccgccg gcccacacgc catgtatggc cgcgtcgtgt tccagaaacg caacggcccg
     1801 ccgaagcggg ccgttgctgc catcacgatc gcgctgcgat cagtggtggt ggccgccgtc
     1861 gccgtggacg tggccgtggt cgatctcttc cttgccggct tcacgcacgt caacgatttc
     1921 gacgtcgaaa tgcaggtcct tgccagccat cgggtggttc aggtcgacgt cgacgacgct
     1981 catgccgacc ttctgcacgg tcaccgcacg cgggccgaag ttggtctgca gcacgacctg
     2041 ctggcccggg gccagcttgg tgttgccgaa atgcttcttc ggcacgcgct gggacaggcc
     2101 ctcgcggcgc tcgccgtagg catcagcggc agtgacgtcg acgctgaagg tcgcgccggc
     2161 ttccttgtcc atcatggcgt tttccaggcc cgggatgatg ttgccgtggc cgatcaggat
     2221 cgccagcggc tcgccgcggt ccttggacga ttcgatcggc tcctggccga cttcggaaac
     2281 ggtgtagtgg aagcggacaa cgcggtcttt ttcgatcttc atgcgcaact ctgtctggat
     2341 ctgccgaagg caggcgggtt ggggcgggtt gtcgcccggc ggggacgccg ccatcatgac
     2401 ggccaatcca aggtggcgca ttatccggag atcatgcaca tcacgccagt ttcgtccggc
     2461 cagcgccggt ttctcgcccc ggccctgctg ctggccctgc ccctgttgat gaccgcctgc
     2521 ggcggtggca aggccacccg cccggccccg cccccgccca cggcgaactg gccaaagacc
     2581 gtgccggaca accccgaggc ggccaactcg gtgctgatgc gcgccatcag cctggtcggc
     2641 acgccctacc gctatggcgg caacaccccg gattcgggct tcgactgcag cggcctggtc
     2701 gcctatgtct atcgcgagat gctggacctg cggctgccgc gcacctcccg cgacctggcg
     2761 gcggtacagg gaccgaagat cgatccgcag cgcctggcca ccggagacct ggtgttcttc
     2821 ggcagccgcg gcagcgtcac ccatgtcggc atttatgtgg gtgaagggcg cttcgtgcac
     2881 gcgccgagca ccggcggcac ggtacgcctc gactcgctca gcggtcccta ctggaaggac
     2941 cactacacag gggcgaaacg cgtccttcgc taaaatgaac aggcgatatg ttcaaaactg
     3001 tgacgaccat caccacgaaa ctaacggttt actaacggaa tttttaactt attgccgctt
     3061 ttacagggca tgatgcccca tcgttttttt cctgtgaccg acgcgtgacg actgacgacc
     3121 tgaaaagcga aggccagact tccgtatctt cacgtagtgc ccgcccgctg ttgcttggcc
     3181 tggcactgtg tctgaccagc cttccggcct ggtcgcagac tgccccgaat cgtttcgatg
     3241 tgaccccggc cccggtggcc gagagcaccg cccgaccggc caccaaggcc gaggccgctg
     3301 ctccgcagcg cagccgcgtc gatgccgccg ccagtgccac gctggccgcc ctgctgccgc
     3361 acctggccgc caatgacacc attccgctga tggaccgctc ggccgtggtg gccggcgatc
     3421 tcagccgcct gctcgccaac tacgacacca gcagcgccgc caatggcagc gttgtcggca
     3481 ccgccgccga taacggcaag gtgcagtcgc tgctgcgccg agcgatgacc ctgctgggca
     3541 ccccgtaccg ttggggtggc agcaacccgg acagcggctt cgactgcagc ggcctggtcg
     3601 gctacgtgtt ccgctcggcg ctgggcatcg agctgccgcg cgtctcgcgc gagatggccc
     3661 acgatgacaa cgccgagctg atcaacgatc gcactgcgct cgccgccggt gacctggtgt
     3721 tcttcggccg caagggccgc gtcgaccacg tcggcatcta tgtcggtgat ggccgcttcc
     3781 tgcacgcccc gagctcgggc aaggacgtcc gcgtggacac cctgctcagt ggttactggg
     3841 gcaacaagtt catgcaggcc cgccgggtcg acctctgacc cgctggcgct acggcgccgc
     3901 ctgaaagaca aaaagccgct gccccgcagc ggcttttttg tttgcgcccc cggtaggtgc
     3961 cgaccttggt cggcatcgcg ccgcctgccc tggtgggcgc cgaccgttgg tcggcactgc
     4021 ctccatccac gcatggcgtg gatctaccag gacccgcctt ggccaccacc gcgccaacca
     4081 gctcccaaac aaaaggcccg ccgggtcagg gcgggccttt tacatctcca cgcaacctca
     4141 ggcgcgtggc ggtgtcgggt ccggatcgtc caccccgaca ttgctggacg gattgtcata
     4201 caccgcctga tcgagcagcc cggtctcctt ggccacgatc accggcacca gcatctggcc
     4261 cgtcacgttc gtcatcgtgc gcatcatgtc caggatgcgg tcgatggcat acaggtagcc
     4321 gatggtctcc agcggcaggt tggccgcgct cagcaccacc gtggccatga tcaccgcagt
     4381 acccggcacg ccggcggtac cgaagctgcc cagcaccgag gcgatcagca ccaccacata
     4441 ctgttccggg gtcagcggca caccgctgta ctgcgagatg aacaccgcgc acagcgccgg
     4501 gtagatcgcg ccgcagccat ccatcttgat gctggcgccc agcggcaccg cgaacgaacc
     4561 gtagtccttg ttcacaccca ggttgtgggt gatcgaacgc agcgccaccg gcatcgcggc
     4621 gaagctggac gagctgacaa acgccacctg catgcccggc gcggcgccac ggaagaactt
     4681 cagtgggttc aggccgtgcg ccagcagcag cgcgctgtag accaccacga tgtgcagggc
     4741 gcaggccacg tacagggcca gcacgaaatg ccccagcggc agcagcttct cgaagccgta
     4801 gctgccgacc aggccagcga tcaggccgaa ggtgccgatc ggggtgactt ccagcacgaa
     4861 gcgggtcacc tggatcatga tgtcgctcat ctggccgacc agcttgcgcg cctcggtcac
     4921 cttctcgccc agcttgacga tggcgaaacc gaccagacca gcaaagaaga tcaccggcag
     4981 gatcgagcca cggcccgcgg ccagcacggt ttcaccggcg gcgttgacct tggtgccgat
     5041 gccggacagc gcgtagaaga cattggccgg caccacatcc agcagcacct gcaccacgct
     5101 gggcacttca cgcggcacgt agttgctggc catcgtcagt tgcaggccac cggcgccggg
     5161 ctgcagcacg gtgcccacgc ccagaccgac gcacaccgcc agcgcagcgg tgatcacgaa
     5221 ccacaggaag gtgcggccac tgagcgcggc gaccgatttc tggccgtgta gcgacgagat
     5281 cgcgttgatg accgcgaaga acaccagcgg caccgcgatc atcttgatca gggtgacgta
     5341 cagctcgccg agcgggccga accacgtttc cgcggccggg ccgagcgccc agccggccag
     5401 cgcgccgagc acgaagccac cgaccacgcg ctgccagaat ggaatccgca gccaggcaga
     5461 gaccagcttc ataggcaatc cagaggggaa ggaagggatg ctggcacgat agcccaaggc
     5521 ggcccgcaga acgaccgccc ggccggcaaa tcagtgtgtc atcggcatgc cttgcgaggg
     5581 cgggcataat gaacgtcccg ttacagtttg tgagatccca gcgtccatgc gccgttccgt
     5641 ctccctgttg gccgcctgcg ccaccaccct gctgctgggc gcctgcgcca gcaccgcccc
     5701 cgcgtccgct ccggccggcc tgaaggtcgc cgtcgatccc gttacccacc cggccggcga
     5761 gacgccgcag tggtggtacc gcagcggcgc ggcccaggcc gcagcgaacg gtgcgatgtc
     5821 cggcaaggcc aggaacgtca tcctgttcct cggtgacggc atgagcctga ccacggtggc
     5881 cgcctcgcgc atctacgaag gccagcaaaa gggtggctcg ggcgaagaga acctgctgtc
     5941 ctgggaacgc ttcccggcca cggcgttcag caagacctac aacaccgatt cgcagacccc
     6001 tgattcggcc ggcaccatga ccgccatcac caccggcgtg aagacccaca tgggcgcgat
     6061 cggcgtcagc gccggcagcc gcaccgactg cgccgacagc ctgtccaagg gcctgctgac
     6121 ctggctgcag ctggccgaca gcgccggcct ggccacgggc gtggtgtcca ccgcacgcct
     6181 gacccatgcc accccggccg ccacctatgc acattcaccc gagcgcaact gggaaaacga
     6241 caccgacctg actgaagcgg ccaaggcggc aggctgcaag gacatcgccc agcagctgct
     6301 gtcgacctcg cgctatggcc gcggcccgct ggtcgccctc ggcggtggcc gcggagaatt
     6361 caccaccgtg gaagagcgcg atccggagta cgacgacaag gtcggccagc gcctggacgg
     6421 ccgcagcctg gtgcaggaat ggcagcaggc ccatccgcag ggcgcctacg tctggaacag
     6481 caagcagctg gccgccgccg ccaatgcgcc ggccatcctt ggcctgttcg agccggacca
     6541 catgcgctac gagtacgagc gcccgcagga tccgggcggt gagccgagcc tggccgaact
     6601 gacggctgcg gcgatcagga atctgtcgaa gcaccgggaa ggctacgtgc tgatgatcga
     6661 aggcgcgcgc atcgaccacg ccaaccacag cggcaacgcc taccgtgcac tgaccgagac
     6721 cgtggccctg tccgatgcag tgcgcgtggc caacgaactg acctcggccg acgacaccct
     6781 gatcatcgtc accgccgacc actcgcacac gctgaacttc gtcggctacc cggcacgcgg
     6841 caatccgatc ctgggcaagg tgaaggacaa gggtggcgaa gatggcgccg gcaagctgga
     6901 ctacgcgctg gacggcaccg gccagccgta caccacgttg agctacgcca atggcccggg
     6961 ccataccggc agcagcaacc agcagccggc cggcccgaag cgctacccgc acaacccgag
     7021 cagcttcgaa ccggccaacg gccgcccgaa cctgcgcgag gtcgacaccg agcatccgga
     7081 ctacatgcag gaagcactgg tgccgatgaa gtccgagtcg cacggcggcg aagacgtggg
     7141 catctgggca cgcggcccgg gcagcaaggc gatccgcggc acgctggaac agaacgcgat
     7201 ctaccacatg atcgtgcagg ccaccccggc cctgcgcgag cgcctgtgcc aggccggcac
     7261 ctgcgatgac aagggcgtgc cggtgcagct gccggcgccg acggccttcg aacgcaaggc
     7321 cgaggccaag tgatcgcact gcaggcccgc cctgcgcctg ccagcggccg cttcgcgcgg
     7381 tcgctggccc tgctcggcgt gctggccagt gccaacgcgc tggcgcaggc accggcgtgc
     7441 aagctgctga ccgacgaaca cgggttgtgg ccgctgccca actgcgaagt ggtcgaccac
     7501 cggccgaaga tccagccgga caccctgaaa gacctgaact ttgatgacca cggcctggcc
     7561 gtggtgtatg ccgaccaggg tttccactac gtcgaccgca agggccgcag cctgccggtg
     7621 ctgacctggg acaacggccc ggagatgccg gaagaaggcc tgctgcgcgg ccgcgtcggt
     7681 aatcgcgtgg gctacttcga tctgacattc cgccaggtgg tgcccggcac cttcgatttc
     7741 gcctggccgt tccgcgacgg cgtggccgag gtctgcaacg gctgccgtcg cggcacgccg
     7801 gatgccgatg gccacacgcc gatggaaggc ggagagtggt tccggatcga ccgctcgggt
     7861 cgtcgggtga agtaggtttt cggcagggct gcgccctgca cctgcagacg caacggcaac
     7921 ggcaacggca acggccgaag caacagcaac agcgtgcatt ccgtgggatg gcggggcact
     7981 gtgggtttgc ggggacggcg caagtacgtc catgtagcct tggtcgccgc atccatgcgg
     8041 ctcacacccc gcaaacccac agtgccccgc cttcgacagt tttccggtgg ccagtagatc
     8101 cacgccatgc gtggatcaga tctgtcagat atcgaattga atccggggtc agatccgttt
     8161 tccgcaggaa aacggatctg actcaagagc aattccgaca gttcgcagga aactgtcgaa
     8221 ggcggggtgg gtccggttgc gggagtgtcc gcggcatgga tgccgcggcc aagcccccat
     8281 ggatgggttt acggcgtctc ccgcaaccag gcccaccccg ccatccttca ggaacccagc
     8341 ttctgctgtt gctgttgctg ttgctgttgc tctggatcgt agcgggtgca gggcgcagcc
     8401 ctgccgggca accctatact tgccgccgtg actgccttcc ctgccctcgt tccgctggat
     8461 gcgccgctgc tggtgggcta cagcggtggt gtcgactcca ccgtgctgct gcactggctg
     8521 tggcgctgcg cccaggcttc cggcacggcg ctgcgtgcgg tgcacgtaca ccacggcctg
     8581 caaccagcag ctgacgactg ggtacggcat tgccagcagc agtgcgcggc actgggcgtc
     8641 gagctggccg tgcgccacgt acagatcgac agaaccacag gcctgggcct cgaaggcgca
     8701 gcgcgcgaag cacgacgtgc agcgttcact gctgaactgc gcgaaggcga aacactggcg
     8761 ctggcacagc accaggacga tcaggccgag accttcctgc tccgcgcgct gcgcggctcc
     8821 ggtgtcgatg gccttgccgc gatggccgat gacagtcagc tcggtacgca ccgcctgtgg
     8881 cgtcccttgc tgcacgcacc gcgcaccgca ctgctcgact atgcccggca acacgcgctg
     8941 cgttggatcg aggatcccag caacgccgaa gaccacgccg atcgcaactt cctgcgcctg
     9001 caggtactgc cactgttgcg ccagcgctgg ccgcacgccg ccgccgcgtt ggccggcagc
     9061 gtcctgcatt gccggcagac ccgcgaactg ctggatgaag aagacgccga gctgatcaca
     9121 cacctggaag tcgctccacg cgtgctgtcg ctgcagttgc tgcgtcaggt gtcaccggga
     9181 cgcgccgcgc gcgtgctgcg cgcctgggtg atcggccatg gtgccgcccc actgccggcc
     9241 acggtgctgc agcaaggcct ggacgaactg ctgccggtcg gcaatgatcg ccaggcgcgg
     9301 gtgcgctggc acgatcatgc catccagcaa tggcgcgagc atgcctatct gctacccgcg
     9361 cagctgccat cgctgccccg cgcgtggcag gccgaatggg atgggcatgc ccccctgccg
     9421 ctgcccgatg gcggccagct gcggctgcag ggcggcgccg ccttcgagcg cccgctgcag
     9481 gtccgtgcac gcttgggcgg tgagcgcatc ctgctgcccg gtcgccagca ttcgcacgca
     9541 ttgaaggact gcctgcaacg cgaacatctc gccccctggc gacgcgcgca gctgccgctg
     9601 atctttgatg gcccgcagtt gctggccgcc gccgacgtgg tcatctccgc gccactgcag
     9661 gcctggttgc aggcccacca ggcacagctg cagtggcgtc ccggcggctg gtgaattgac
     9721 ccccgcgcgc ggcccgtcca cacttgccac atggccaaga agtcccccga aaacgcctcc
     9781 ccggtcgccc agttcgagca gtcgctcgaa tcgctggaac agctggtgga gcagatggaa
     9841 accggcgagc tgagcctgga agcctcgctc agtgcttacg aacgtggcgt cggtctgtat
     9901 cgccagtgcc agcaggcgct ggagcaggcc gaactgcgcg tgcgcctgct cagcgatccg
     9961 gcgcagccgg aagcatccga gcccttcgat ccgcccaacc atgacggctg aggttctgtt
    10021 cgcgcgctgg cgcgaccgta tcgaaagcca gctcgacgct gccctgccct cgcctgccga
    10081 agcaccgcag cgcctgcacc aggccatgcg ctattcggtg ctgggcggtg gcaagcgcat
    10141 gcgcccgctg ctggtctacg ccagtggcca cctgttcggt gcacagctgg aaagcctgga
    10201 tgcggcggct atgtccgtcg aactcatcca cgcctactcg ctggtgcatg acgacctgcc
    10261 ggcgatggat gacgacgcgc tgcgccgtgg caagccgacc acccacatcg ccttcgacga
    10321 agctaccgcg atcctcgccg gcgacgcgct gcagacccgt gccttcggcc tgctggccga
    10381 tgcaccgctg ccggccacgc tgcgcgtggc ctgcctgcag accctggccc acgcctccgg
    10441 cgcgtccggc atgtgcggcg gccaggccct ggatatcgat gccaccggcc agcagcagac
    10501 gctggcggca ttgacccgca tgcatgcgct gaagaccggc gccctgatcc gcgcggcagt
    10561 gcgcatgggc gcgctgtgtg gccaggccca cgaaccgcag ctggcccagc tggacagctt
    10621 cgccgatgca ctcggcctgg ccttccaggt acgcgacgac atcctcgatg tcgaggccag
    10681 ttccgagcag ctgggcaaga ccgccggcaa ggaccaggcg caggacaaga gcaccttccc
    10741 cgccctgctt ggcatggacg gcgcaaaggc ccagctgcac gaactcgctg cacgcatgca
    10801 gtcgatcctg gccgggtatg gcgaggaagc cgatgcgctg cgtgcgctgg cgacgctggc
    10861 ggtcgaacgc gaccattgat cgctcgccgg gcaccgcccg tcgctccccg cacatgaaaa
    10921 cgcccggcaa tgccgggcgt tttcagttcc gcatgcagcc ggtattactt gatcaggcgc
    10981 agcgcgaacg ggtagcgata ggcttcgccg ttgttggcct tgaccgctgc gatgatgctg
    11041 aacaccaggc tgatgatgcc gacgatcggg gccaggaaga cgccgatgat cacgatggtc
    11101 aggatcatgc tgatgaccat ggcgatggtc acggtgatct ggaagttcag ggcttccttg
    11161 gcctggtcgg tcacgaaagc cttgccagca tcgtccttgt tgatcagcca gatgatcagt
    11221 gcgccgatga agccggtgaa gatgcccagc agatgggcag ccagggccat ggtgcgctgg
    11281 tcggccggca cgtcggtggt ggccggcggc ggcgggacgt tatcgaattc gctcacgaca
    11341 aaactccttt tcattgggtg gtcttgaccc accagcacca agctggttgc gtcaggcggg
    11401 catagcttac gccatcgacg ccatcaatca ttaccggcga tggtcatccg ccccagcagg
    11461 atcgaaccgg tccggatgtg cgagcgcggg tcgacgtcgc tgccgaccgc ttcgatgctg
    11521 ctgaacatct cgcgcaggtt gccggcgatg gtgatgccat ccaccgggta ctggatctcg
    11581 ccattctcga cgcggaagcc gccggcaccg cgcgagtagt cgccggtcac cccgttcacg
    11641 ccctgcccca tcagctcggt caccagcagg ccatcgccca tctggcgggc gatctcctgc
    11701 agggagcccg cgttggcggc cagttgcagg ttgtgcacgc caccagcatt ggcggtggtc
    11761 tgcaggccca gcttgcgcgc cgagtagctg cccagcacat agcgctgcag cacgccgtca
    11821 cggaccaggg ccgaagcacg ggtggccacg ccgtcaccgt cgaaggcggc cgagcgcagg
    11881 ccacggcgca ggtggggcag ttcctcgatc tgcatccagt ccgggaacag ctgctggcca
    11941 acactgtcca gcaggaagct ggcatggcgg tacagggcac cgccggacac cgccgacagc
    12001 aggtgaccga ccaggctgcg cgcgacttcc ggggcgaaca gcaccggcat gctgccggtg
    12061 gccatcgagc gaggctgcag gcgggcgacg gtacgctcgg cggcacgacg accgaccagg
    12121 cccacctcct ccaggtcctc gcgggccagc gcgctggtgt accagccatc gcgctgcatg
    12181 ccatcgccct ggccggcgat cagcgcacag cccaccgaat gatgggtgcc acgctcacgg
    12241 ccgaaaaagc catgcgaatt ggcgtacacc gacaggctct gcatgctcga caccgaggcg
    12301 ccgtcggagt tacggatctg cgcatcggcc tcacgacctg cgttctcgca ggccagggcc
    12361 aggtccaccg cctcgtcggc ctgcagcgcc cagggatgcc agctgtccag gtcggggaag
    12421 tcggtcgcca tcagcgccgc ctcggccagg ccggcggccg ggtcgtcctc ggtatgccgg
    12481 gcgatcgcac aggcctgctc gaccgtggcg gtgaggctgg cctcgttcag gtcgccggtg
    12541 ctggcgctgc ccttgcgttg gccgaaatag acggtgacgg cgatacctcg gtcgcgggtg
    12601 gactgcacgg tctcaacctc gccaaggcgg acattgacct ccaggccacg gtcctcgctg
    12661 cagctgacct cggcctggct ggcgcccagc gcccgggcac ggtcgagcag ctgctgggaa
    12721 aggtcggcca gccgttccag ccgggccggg ctgtcgtcgc cgacagcgac ttcaggggcg
    12781 atcacgttca atgctttatc ctgtacgggt tgggcccggc atcacgccgg gcgacttttt
    12841 tgagatcagg taggaacgat gcgcggacgc gacgaagaaa ccggtgaatt ccacgacaag
    12901 agccgcagcc agaaccggcg cgatgcgctc gacgtcctgg ccctgggcga gaagctggtg
    12961 tcgttgaccc cggcccagct ggcgcgcctg ccgattccgg aagacctgct gccgcatatc
    13021 gccgagtgca agcgcatcac cgcccacatc gcccacaagc gccagctggc gttcctggcc
    13081 aagcacatgc gccgcgaaga agacgccacg ctggatgcga tccgcgatgc gctggacgcc
    13141 aacagcgaaa ccggccgccg cgaagtggcg atgatgcacc gcgcggaaga ctggcgcgag
    13201 cgcctgctgg ccgagggtga caaggcactg gcggcactgc tggacgacta cccgcaggcc
    13261 gaccgccagc agctgcgcac gctggtgcgc aatgcccagg ccgagaaggc gaagaacaag
    13321 ccgccgcgcg cctaccgcga aattttccag gtgctgcgcg ccctgatgct gccggccgcg
    13381 ttgggcctga aggccagcgc cgaagacgcc gaccccattg aaaccgacga agccgacgag
    13441 gactgagtcc tcgccggcag gggcggtggc actggccatc gcccggctca ggcctgggta
    13501 ccgccgacgg tgatgccctc gatcagcaac gagggctggc cgacacccac cggcacgctc
    13561 tgcccgtcct tgccgcagat gcccacgccc tcgtccaggg ccaggtcgtt gccgaccatg
    13621 cgcaccttct gcatggtttc cggaccgttg ccgatcaggg tcgcgccctt caccggcgtg
    13681 gtgatgcggc cgtcctcgat caggtaggcc tcggtggccg agaacacgta cttgccactg
    13741 gtgatgtcga cctggccgcc gccgaagttg accgcgtaca ggcccttctt caccgaacgg
    13801 atcatctcct gcgggtcatg ctggccggcg cgcatgtagg tgttggtcat gcgcggcatg
    13861 gtcatgtgcg cgaacgattc gcggcgacca ttgccggtcg gcgccacgcc catcaggcgc
    13921 gcgttgaggc tgtcctgcat gtagccgacc aggatgccgt cctcgatcag cgtggtgcac
    13981 tggctgggat gaccctcgtc gtcgatgttc aacgaaccac ggcgtccatc cagcgtgccg
    14041 tcatcgacga tcgtcacgcc cggggcggca acgcgctcgc cgatgcgccc cgcgtagacg
    14101 ctggtgccct tgcggttgaa gtcgccctcc aggccatggc cgaccgcttc atgcagcagc
    14161 acaccgggcc agcccgggcc cagcaccacc ggcatcacgc cggccggtgc cggtaccgct
    14221 tcaagattca ccagcgcctg gcgcagcgcc tctcgggcga aggcttccgg gcggccgtcg
    14281 gcgaacagct cctcatagcc atagcgacca ccgccaccgg catagccgga ctcgcgacgg
    14341 ccgttgtgct cgacgatcac ctgcacgttc aggcgcacca gcgggcgcac gtcggcgccc
    14401 agcacgccgt cgctgcgggc gatcagcacc gtatcgacgc cgccggacag gctgaccatc
    14461 acctgcttca cgcgcgggtc ggcagcacgc aggtagccgt ccaggcgctt gagcacctcg
    14521 accttggcct cgttgccgac gccatcgatc gggtccagcg ccggatacag cgcgcgcgcg
    14581 ttgccgcgca gcagcgagcg cccggtctgg gcaccacctt cacgcgagat cgcgcgcgcc
    14641 gactgcgccg ccacccgcag cgcatcggca tggatgtcgt cggagtaggc gaaaccggtc
    14701 ttctcgccgg aaatcgcccg cacgcccacg ccctgctcga tggaatgcgc gccgtccttg
    14761 acgatgccgt cttccacgct ccagctctcg cggcgggcgt gctggaagta aaggtcacca
    14821 aagtccacac cggggccgag cagctgcccg aaggtgtgct ccaggccagc ggtatccagg
    14881 ccaccagggc gcagcaggcg gtcttgggca agcgtcaggg cgatatcagt catggttctc
    14941 gatctgggga tgcgggggcg ctcaggcaag ccccgtgaac aggaaagccg cgctcaacgt
    15001 gagcgcggca ggccggtgac ggtcggcgga atggccggtg ccggtgccgg agccttctcg
    15061 cggctgcgct cgatcacttc caccttcggt tccttccatg gaccggtcac cttgtaggta
    15121 cgggcgccaa tctcgcccaa tggtttggac aataccgcat tggtggccgc gcccagcgcc
    15181 gcccccaccg ggccaccggc caccgccccc accacggtca gcagattgcc tgcgcgcggg
    15241 ttgacgtcga tggtctggtc gaactgctgg ttgcgcaggt cggcctggcc gcggatggtg
    15301 atgttggctg ccgggccttc gatcagcacc ttgtctgtgc gcgccatgcc ctggccgaac
    15361 tgcatgctgc cgtcgatctg gttgaacgcg aagcccttgg agaagaagtc gcggaagtcg
    15421 aacatcaggc gccgcggcag ctgggtcacg ctgagcaggc ccagcacgcg gccggcgccc
    15481 ggctccagct ccagcagctg gccgttgcgt gcgtgcaggt ccaggcggcc ctgcaggttg
    15541 cccagctgga agtccgacgg ccccccactc cacgtggcct gcagctgcgc ctggccggaa
    15601 ccgccacgca gctggccgcc gtagtcgagg ttctgcatca gtccgcccag atcctcgctg
    15661 cgcacctgag cggtcagctc ggtgcgggca ccaccgctgc ggcccagcca gcgaccgctg
    15721 atgtcgatct cctggtcggg cgcacggaag cgcagctcat ccacgttcag gccattggcc
    15781 agcggccgcg tacgcagcac cgcctggccc agcaccacct tgccgaactt caggtcggcg
    15841 atgtccagcg cgaacggcgg cagcttggcc gggtccatgt cattggcgcc tgcctgtacc
    15901 cgtgccggtg cggccggtac acctggagcc gccggcaatg actgccagtg cacgcggtcg
    15961 agctggccac tgatggtgcc gccgtctgca ttggggacgg tcaggcgccc ggccagcgac
    16021 gggccgtcca ggcgtacatc cagtgcctgc gctcccgggc gcagctgcaa ccgggtctgc
    16081 tcgaacacac caccgatcag catcagcttg ccgacctgca cgtccaccgc acgcagcggc
    16141 atgccgtcat cgtcgttgcc accacgggcc aggccgatcc actccagcgc atccagggtc
    16201 gggctgcggc cattcacgga cagtccgctc ggtggcggct cgcgatcggc atggtcgctg
    16261 cccagcgtca cctgcacacc cgtctggttg ttgtggctgc gcgcagccag cgccaggcgc
    16321 tggccgaacg ccacgtcgat gcggccggcc cccatcggca gctgtgcagc cacggtggtc
    16381 gccaacggct cggcagccgg tttgtccagc ggcgccggca ggtccagccg ggtcccgacc
    16441 agatcggagc tcaaccgcag ctcgctgggc ggcgcaggcg cccccggagc gaccttgggc
    16501 agattgaccg cgatggtcca cggcgaggtg ccggcgatgt agggcttcag ccacgccatt
    16561 tccggcgcgc ggtcgatcag cacgccagca tcgaggttgg ccgacaactg cgattcaaag
    16621 gccagcttgc tgtcgtgcac gtagccaccg gcacgcaggc tcagacgacc gtcctggccg
    16681 aggtggcgca ccgccagttc ctcggcgccg aaaccgccgt tgctgtagcg cgcctgcccg
    16741 tgcatgttgt caaaggtgag ctggaagcgc ttgtcgacca gcttcacgcc ggccagatcg
    16801 accgttccct gcaggtggcc gccaccttca tcgtggtgca gcggctgcag cagatcgaag
    16861 gtcacatgcg ccgggcccgc agcggtgagg ttgtccaggg tgtcgccata atccttgtgc
    16921 agcgggctct gccgcagcat ggccagcagc ctgccggcct cgctctgcgc atcggcacgc
    16981 acgtacagcg gctgctgccc gaaatcctgg atgcccgcct cgaatttctg caccgccacg
    17041 ccggccagat cgccgcgacc gtgcatgtcg aagccggggc cgatgaaggc gatatcggcg
    17101 tcgacctggc gcatcaacgg ccagtcgtgc tggaagcgga tgtcaccatt ggtgatatgg
    17161 ccggtcgcct cgaagcggcc atcgttgttg tcgaacggcc agtcgtccag gtcgccactg
    17221 accaggccga tgccgttgcg cacctgccca ccggccagcg ccatgtccag ccagtcggtg
    17281 gcgcccttgc tcatcttgga gtggatccag aagcgcttgg ccgcggtcat cggcacgtcg
    17341 tccagcttgg ccgccagctg cagccacggc cgcgtaccgt cgccctggaa ccagacacca
    17401 ccgcgcacgt ccgccgcata atcggtgcct tccacgcgca tcgctgccgt gccgatgcgc
    17461 cagccaccgc cttcatcgcg ccagcccacc acctggcccg ccaggtgcag atcgtggcgc
    17521 acgccgaagc cggtcggcca atcgaactgc agctggcgtt gcggctgcag ctgcaggctg
    17581 aagccatccg cgtcgccttc gaagcgcccg cccaggccgc gcaggccggg cgaattgccc
    17641 acgctggcga agcccagcga ctgcagttcg ccctgcgccc acagcgggcc atcgcgttcg
    17701 cccgccagct gcagctcgcg cacgtccagc tgcggcctgg acaggaacag ccagcgacgc
    17761 aggcccggtt caagacgatc gctcagggcc agcgcacgca gcgcgatgcc ggcctgcact
    17821 tcgcgagaac tgacccgcag ctgcttgccg agctgcagct gcaggccatc gagctgctgc
    17881 tcgccttctt cggttttcag gcgcaggcgc ggcacctgca atgcccagcc atcggcctgg
    17941 cgctgccagc gcaggcgtgc ctgcaaccgc tgcagctgca gctgcggagc cgccatcgcg
    18001 ggcatcggtg cgccatcgat gcggacatca cgcaggtccg aatcggtggt caccgccacc
    18061 ggcgcgaaat cgcgcagggt cagccacagg ttgagttcgc ccttgccttc gcgcaggcgc
    18121 acaccgccgg ccgccagcag cggcgaccag gcatgaaaat cgaccggatc ggcgcccagc
    18181 caggcctggc cgttgccgcg cacgcggtcc acgtccagca ccgccgtcaa cggcagcgct
    18241 tcggtctggg cccaggcgcg cacgcctaca cgcaggcggt cgccattgac ccgcaggcgc
    18301 acgtcgatgc gtggcagcgt ggtatcgatc cccagccccg gcgcatgcac gcccaggcgg
    18361 cccccgatca cctgcagttc gcccagacgg cgcagcgcat ccagcgggtc cccgccattg
    18421 gcggcctgcg gcaggccacg caccgaccag cggccgtcct cgccctgctg caggtccagt
    18481 gccaggccac gcaggcgcag ttcggtcaac gagcggccgg gcagcagccc gctgtacatc
    18541 gataccagca cctcggcctc gccgatcgcc aggccctggc cggcgccaat gcgcaggccc
    18601 ttgagctgca gcagcggacc acgccgggtc caggccgtct gcagctggtc gaaacgcacc
    18661 ggctggccgg cgcgttcact caaccaggcg gcaatcctgt cgggatggcg ctcggccagc
    18721 ggcagcagct ggctgagggt gcccaccagc agtgccagcc cgaccaggcc caccgcgcag
    18781 gcggcaatga aatgacggcg gatccttcgc agtcgcaggc gcggcggcgc gctcatcggc
    18841 caccgccggc ctgcggccgg cgaggatcag agcagaacaa catcgaattg ctcctgcagg
    18901 tactgctcgt ccgcctggaa tcggatgctc ttgccgagga attcctccag ctcggccacc
    18961 gccgcggatt cctcgtcggt gatgcgcgcg accaccttgg tcgaggcgat caccagcagg
    19021 cgcgcggcat cgaactggcg cacggcacgg gtgatctcgc ggaagatctc gtaggtcacc
    19081 gtttcggtgg tcttgatgct gccgcggccg ctgcactgcg ggcaggtttc cgacagctgg
    19141 cgctccaggc tttccaccgt gcgcttgcgg gtcatctcca ccaggcccag cggcgagaag
    19201 tcgtacaccg tggtcttggc atggtcacgg gccagcgcct tttccagcgt acgcaatacc
    19261 tggcggcggt gctcggcatc atccatgtcg atgaagtcga tgatgatgat gccgcccagg
    19321 ttgcgcaggc gcagctgccg tgccaccgcc tgcgccgctt ccaggttggt gcggaacacc
    19381 gtctcttcca ggttgcgctg gccgaggaac gaaccggtgt tgacgtcgat ggtggtcatc
    19441 gcctcggtct ggtcgatcac caggtaacca ccggatttca gcggcacctg cttgtccagc
    19501 gcgcggccga tctcgtcctc caccccgaac atgtcgaaga tcgggcgatc gccgctgtac
    19561 agctcgatct tctccgccag caccggcatg tacttggcaa caaaggcctg caactgcgcg
    19621 aaggtctcct tggagtccac cttcaccttg tccacatcct tgcggatcag gtcgcgtacc
    19681 gatcgcagcg gcaggctcag gtcttcatag atgttgctgc acgaggccgc ttcgcggcca
    19741 cgacgctcga ccacgttcca tacgcgcgac aggtaggcga tgtcctcggc gatggcttcg
    19801 gccggctggc cctcggcatt ggtacgcacg atgtagccgt agcccccgtg ctgcgccgac
    19861 agttcggtca ccagcgcctt caggcgcgca cgctcggttt catcctcgat gcgcgccgac
    19921 acgcccacca ccttggactg cggcagcagc accatgtagc gcgagggaat gctgatctgg
    19981 gtggtcaggc gggcgccctt ggtgccgatc ggatccttca ccacctgcac cacgatgtcc
    20041 tggccgtcgc gcagcagctc gacgatcggc acgctggacg gcggcggcag cgtggtgttc
    20101 tcggtgtcgg cactggctac cggcgccggc cgcaccacgt cgttggcgtg caggaacgcg
    20161 gcacgctcca gcccgacttc gacgaaggcc gcctgcatgc cgggcatcac ccgctgtacc
    20221 ttgcccttgt agatgttgcc gaccacaccc cggcgccagc cgcgctcgat gtgcagttcc
    20281 tgcagcatgc cattttcgat caccgcgacc cgggtctcgc gcggggtcac attgaccagg
    20341 atttcctcag acatcggcag cctccctggc ggcatcggca gtgggggccg gcacgccaca
    20401 gcgcgccagc aaacgatcgg tgtgcagcaa cggcagcccc atcaccccgg agtaactccc
    20461 ggacaggtgc tcgatccagc gctcggcccc gccctggatg gcgtaggccc ccgccttgtc
    20521 cagcggttcg ccggtggcca cgtaggcggc gatgtcggcg gcgtcgatcg gggcgaaggt
    20581 cacttcagaa atgaccagct cgctgtccag cccgtccgcg ccgaccacca ccaccgcggt
    20641 catcacctga tgggtacgcc cggcaagacg cgccagcatc gcccgcgcat cggcggcgtc
    20701 ggtgggcttt ccgaacacgt cgccgtccag caccacctcg gtgtccgaac cgagcacccg
    20761 cgcctgcggg tcatcggcca gcacccgggc caggccggcg cgcgccttgt cggcggcgac
    20821 ccggcagaca tactgttcgg cgctttcagc gggcgcgcgc tgctcgacga cctcaaggt
//
