LOCUS       NZ_CP116604            23501 bp    DNA     circular CON 01-MAR-2024
DEFINITION  Streptococcus sp. HN38 chromosome, complete genome.
ACCESSION   NZ_CP116604
VERSION     NZ_CP116604.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus sp. HN38
  ORGANISM  Streptococcus sp. HN38
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2521977)
  AUTHORS   Yang,Q.
  TITLE     Integrative and conjugative elements can act as vectors for
            unconventional circularizable structure carrying optrA in
            streptococcus suis
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2521977)
  AUTHORS   Yang,Q.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) College of Veterinary Medicine, China
            Agricultural University, No. 2 Yuanmingyuan West Road, Beijing,
            Beijing 100193, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: GS De Novo Assembler v. Unicycler v.0.4.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1.5x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/01/2024 01:35:53
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,496
            CDSs (total)                      :: 2,423
            Genes (coding)                    :: 2,347
            CDSs (with protein)               :: 2,347
            Genes (RNA)                       :: 73
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 76
            CDSs (without protein)            :: 76
            Pseudo Genes (ambiguous residues) :: 0 of 76
            Pseudo Genes (frameshifted)       :: 27 of 76
            Pseudo Genes (incomplete)         :: 47 of 76
            Pseudo Genes (internal stop)      :: 23 of 76
            Pseudo Genes (multiple problems)  :: 20 of 76
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:57:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2064139
            Orig. end                         :: 2087640
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP116604.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23501
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /region_number="5"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     cand_cluster    1..23501
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23501
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13501](-)"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13501)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     gene            complement(73..1833)
                     /gene="lpdA"
                     /locus_tag="PHA78_RS10035"
     CDS             complement(73..1833)
                     /EC_number="1.8.1.4"
                     /GO_function="GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /GO_process="GO:0051068 - dihydrolipoamide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="lpdA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984864.1"
                     /locus_tag="PHA78_RS10035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="WP_099806610.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.6e-65, bitscore:
                     216.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIEIIMPKLGVDMQEGEIIEWKKQEGDFVNEGDVILEMMSDKTS
                     MELEAEESGVLLKIVHGNGATVPVTEVIAYLGAEGETVEVGAAPAPAEVAQATADLKAA
                     GLEVPVAPAAAPQAPKAELAADEYDMVVVGGGPAGYYAAIRGAQLGGKIAIVEKSEFGG
                     TCLNKGCIPTKTYLKNAEILDGLKIAAERGINLASTNYTVDMDKTVDFKNKVVKTLTGG
                     VQGLLKANKVTIFNGLGQVNPDKTVVIGDKVIKGRSIVLATGSKVSRINIPGIDSKLVL
                     TSDDILDLREIPKSLTVMGGGVVGVELGLVYASYGTEVTVVEMADRIIPGMDREVSVEL
                     QKVLSKKGMKFLTSVGVSEIVEANNQLTIKLNDGSEIVSEKALLSIGRVPQLAGLENLN
                     LELDRGRIKVNEYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENAIHGNHHKAKLD
                     FTPAAVYTHPEIAMVGLTEDQAIEKYGKENILIGRNSFTGNGRAIASNEAHGFVKVIAD
                     KKYHEILGVHIIGPVAAEMINEAATIMESELTVDDVAASIHGHPTFSEVMYEAFLDVLG
                     VAIHNPPKRK"
     gene            complement(2103..3488)
                     /locus_tag="PHA78_RS10040"
     CDS             complement(2103..3488)
                     /GO_component="GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002885106.1"
                     /locus_tag="PHA78_RS10040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="WP_105147473.1"
                     /transl_table=11
                     /translation="MAIEIIMPKLGVDMQEGEIIEWKKQEGDFVNEGDVILEMMSDKTS
                     MELEAEESGVLLKIVHGNGATVPVTEVIAYIGAEGETVEAGASATPVAPAAAIEEVPAG
                     RTPVIVAPAVAAKPQGGGKVRATPAARKLARELGIDLGLVPGTGANGRVHKADVEDFKG
                     AAPKATPLAARIAADQGVDLSTLTGSGVNGKIVKDDVLAVLAPAAVETAAPAPKTEEKP
                     AKELPEGVEIIKMSPMRKAISKGMVNSYLTAPTFTLNYDIDMTNLMALRKQVLEPIMNK
                     TGLKVTFTDLIGLAVVRTLMKEEHRYMNASLINDAQEIELHKFVNLGIAVGLDDGLVVP
                     VVHGADKMSLSDFVVASKDVIKKAQSGKLKGAEMSGSTFSITNLGMFGTKTFNPIINQP
                     NSAILGVASTVQTPVVIDGEIKIRPIMALCLTIDHRIVDGMNGAKFMVDLKNLLENPLE
                     LLI"
     gene            complement(3827..4822)
                     /locus_tag="PHA78_RS10045"
     CDS             complement(3827..4822)
                     /EC_number="1.2.4.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942393.1"
                     /locus_tag="PHA78_RS10045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="WP_099806608.1"
                     /transl_table=11
                     /translation="MAETKVMALREAINLAQSEEMRKDEKVFLMGEDVGIYGGDFGTSV
                     GMLDEFGPKRVRDTPISEAAIAGSAVGAAQTGLRPIVDLTFMDFVTIALDAIVNQAAKT
                     NYMFGGGLKTPVTFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGTANDAKGLLKS
                     SILDNNPVIFLEPKALYGKKEEVNLDPDFYIPLGKGEIKREGTDVTIISYGRMLERALK
                     AAEEVAAEGISVEVVDPRTLIPLDKELIIESVKKTGKVILVNDAYKTGGFIGEIASIIT
                     ESEAFDYLDAPIIRIASDDVPVPYANILENAVLPNVEKIKEAIYKQVNRG"
     gene            complement(5608..6576)
                     /locus_tag="PHA78_RS10050"
     CDS             complement(5608..6576)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258167.1"
                     /locus_tag="PHA78_RS10050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiamine pyrophosphate-dependent dehydrogenase E1
                     component subunit alpha"
                     /protein_id="WP_024379494.1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-06, bitscore:
                     25.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSISKEQHLDMFLKMQQIRDVDMKLNKLVRRGFVQGMTHFSVGE
                     EAAAVGPIAGLTDEDIIFSHHRGHGHVIAKGIDINGMMAELAGKATGTSKGRGGSMHLA
                     NVEKGNFGSNGIVGGGYALAVGAALTQQYLGTDNIVIAFSGDSATNEGSFHESMNLAAV
                     WNLPVIFFITNNRYGISTDISYSTKIPHLYQRAAAYGIPGHYVEDGNDVIAVYEKMQEV
                     IEYVRAGNGPAMVEVESYRWFGHSTADAGVYRTKEEVNEWKAKDPLKKYRKYLTENKIA
                     TDEELDAIEAQVAEQVEASVKFAQESPDPDISVAYEDVFVD"
     misc_feature    6732..6747
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.6"
                     /tool="antismash"
     gene            6808..7467
                     /locus_tag="PHA78_RS10055"
     CDS             6808..7467
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637160.1"
                     /locus_tag="PHA78_RS10055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="WP_024416372.1"
                     /transl_table=11
                     /translation="MEFDLFLMICNYIGTIAFAVSGAVKGFKKKLDIFGISLLGIITAV
                     GGGIIRDTMANRIPAALTDPTAIYLSLGVAISMYLIVINLKQDKPPGKKMIHFLSQTNL
                     IFDAIGLAIFALIGASTGISLQLNALTSGILAALTGVGGGIARDLLVNETPIVLKEDVY
                     AVLAFFSGVLYHLCVVNWKLPQIPTFITIFTISLIIRLLVIKYKINLPNMESKRKV"
     gene            complement(7503..8660)
                     /locus_tag="PHA78_RS10060"
     CDS             complement(7503..8660)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637161.1"
                     /locus_tag="PHA78_RS10060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbohydrate-binding domain-containing protein"
                     /protein_id="WP_272158112.1"
                     /transl_table=11
                     /translation="MKTNFKKLLYSGVTLMSIGILVACSSTSSSMTTSSSAATSQSSAS
                     TTSSNSTSSDSSSSSSSIDWSALPTTEVTLSNDGLKITEGGTYILTGSTTAGVTVETDA
                     NVRIILAGAEISSSDTAAINVINADNVELEIKDGTTNTVKDTSNHTDTNIEGAIHVEAD
                     LTITGNGSLTVEGNFQDGIVSTDDLVVNSGNITVTAVDDGIRGKDSLTINGGTINVTAG
                     GDGIKSTNDTDTTKGYTTITGGEITVKAGDDGIKAETALTIDGGTITVSESVEALEGTN
                     ITINGGTIDVYGSDDAINAASTTSSEIFIKVTGGDLKVAVGSGDTDAFDANGDIYISGG
                     TIAVTAPTSAFDFDGTAELTGGTVTVNGEQITQITATGPGGRGGW"
     gene            complement(8913..10004)
                     /locus_tag="PHA78_RS10065"
     CDS             complement(8913..10004)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681382.1"
                     /locus_tag="PHA78_RS10065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_024376422.1"
                     /transl_table=11
                     /translation="MSKRFLNLYMMNIFLSGLPYYFIGVLLLKHLGFSFTEIATLSVIT
                     ELCGSVFDIPLSFLSSKFGYKKILILSNLLLTLALSCLLLGQSKIIYISAIFFGLSESL
                     SSGVLNAYNFELIGNELVYQSFLKYLNTVKYIFIAIITIISPYLLNRNYIYPIIISIVF
                     VIFSLLNVIQLPEIKNELPNDSRFFSFDDVKTIPWYLLLLGVAFSTLIMISNSYAGIFL
                     NEQGLSLDMLGIVLFMFNIAMALGSYLKMKFEISLLLPVLAIFMFFQTNVFIEIVLFLL
                     MRVLNSSYNNHFYSMFNSSIEKNRAVSWSVYNLFISISFMVSDFLAGIFADNFGIRSNY
                     LLFGIITLFSFLFFSFSNREERT"
     gene            complement(10001..11302)
                     /gene="kwcM"
                     /locus_tag="PHA78_RS10070"
     CDS             complement(10001..11302)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /GO_process="GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="kwcM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587087.1"
                     /locus_tag="PHA78_RS10070"
                     /note="This protein, a peptide-modifying radical SAM/SPASM
                     domain protein, cyclizes KxxxW-containing RiPP precursor
                     peptides by creating a Lys-to-Trp crosslink; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="KxxxW cyclic peptide radical SAM maturase"
                     /protein_id="WP_099806605.1"
                     /sec_met_domain="Streptide_RRE (E-value: 1.4e-22, bitscore:
                     77.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.1e-17, bitscore: 62.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.6e-05, bitscore: 22.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 8.3e-12, bitscore:
                     42.5, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSIRLEKFGGILINKTNFERIELDETEAFFLYLVQNHGIEIATS
                     FFKKEIEIGKLERALSLNIYSDNNIEDSSNNPYETLQNARKHVAKLKKHNILSFPLELV
                     IYPSMYCDLKCGFCFLANREDRNAKPAKDWERILRQAKDNGVLSVSILGGEPTRYFDID
                     NLLIACEELKIKTTITTNAQLIKKSTVEILAKSKYITPVLSLQTLDSKLNFELMGVRPD
                     RQIKLAKYFNEVGKKCRINAVYTKQSYEQIIELVDFCIENKIDRFSVANYSEVTGYTKI
                     KKKYDLADLRRLNEYVTDYITQREANLNFATEGCHLFTAYPELINNSIEFSEFDEMYYG
                     CRAKYTKMEIMSNGDILPCIAFLGVNQTKQNAFEKDLLDVWYDDPLYGGIRSFRTKNSK
                     CLSCGLLKICEGGCYINLIKEKSPEYFRDSVCQL"
     aSDomain        complement(11063..11299)
                     /aSDomain="Streptide_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM enzyme in a
                     streptide-like cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_PHA78_RS10070_Streptide_RRE.1"
                     /evalue="1.60E-24"
                     /identifier="RREFam022.1"
                     /label="PHA78_RS10070"
                     /locus_tag="PHA78_RS10070"
                     /protein_end="80"
                     /protein_start="1"
                     /score="77.2"
                     /tool="antismash"
                     /translation="NSIRLEKFGGILINKTNFERIELDETEAFFLYLVQNHGIEIATSF
                     FKKEIEIGKLERALSLNIYSDNNIEDSSNNPYET"
     misc_feature    complement(11299..11308)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            11331..12366
                     /locus_tag="PHA78_RS10075"
     CDS             join(11331..11827,11826..12366)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1238: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /locus_tag="PHA78_RS10075"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS630 family transposase"
                     /protein_id="WP_099778716.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MKLTIEQTKELKTYLKDKTYSPFHRRLQVILFRAEGLSYKEITNL
                     IGYSKYTIWSLQRKYELEGISALVRETRGGRNRQYLTLQEEEAFLKEQLTASLNGEFVT
                     INSLYEAYQKRVGHPTTKEGFYAILKRHGWRKVTPRPEHPKKADAETILASKNKIFIHE
                     NRKKRFKNSRRYHKVRLMYQDEAGFGRISKIGKAWAPKGVRPHVHSHYIREYRYCYGAV
                     DAHTGESFFIIAGGCNTDWMNVFLKQLSEAYPDDYILLVMDNAVWHKSSTLEKPHNIGF
                     EFIPPYTPEMNPIEQVWAEIRKRGFKNKAFKTLDDVINKLQEVIRELDWSILKPIVSRQ
                     WFKNT"
     gene            complement(12489..12557)
                     /locus_tag="PHA78_RS10080"
     CDS             complement(12489..12557)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04079.1"
                     /locus_tag="PHA78_RS10080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="KxxxW-cyclized peptide pheromone"
                     /protein_id="WP_099778207.1"
                     /transl_table=11
                     /translation="MSKELEKVLESSAMAKGDGWHV"
     misc_feature    12540..12555
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.45"
                     /tool="antismash"
     gene            complement(12638..13501)
                     /locus_tag="PHA78_RS10085"
     CDS             complement(12638..13501)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681501.1"
                     /locus_tag="PHA78_RS10085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="WP_024376424.1"
                     /sec_met_domain="TIGR01716 (E-value: 8.1e-46, bitscore:
                     153.5, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNFGEIFKKFRESRGLKLKDVAKVGISTSQLSRFEKGETDLTIS
                     KFLLILDEINMPIDEFMYAVHDFHRDELNELLSKVRYYVSTRDVEGMKKLLYSQIESED
                     KREKFYHINIILLKIRLQDLSGENYYNDKDLDELTDYLFSVEYWGYYELLIFMNTLDVL
                     KYDVFIVLAREMSRRSDFFKEIPNNRRLISTMLLNAYITCIERQNLIDALYFEKQLKQC
                     FFIETEIYERLVFLYAQNLYRYRKTGSKFAIVEMRKCIGAMKLAGSDHVAQIYEEHLKK
                     ILTENS"
     misc_feature    complement(13578..13593)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            complement(13718..>13876)
                     /locus_tag="PHA78_RS10090"
                     /pseudo=""
     CDS             complement(13718..>13876)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /locus_tag="PHA78_RS10090"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="group II intron reverse transcriptase/maturase"
                     /pseudo=""
                     /transl_table=11
                     /translation="YIANKVSG"
     misc_feature    13942..13954
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 22.66"
                     /tool="antismash"
     gene            complement(14047..15157)
                     /locus_tag="PHA78_RS10095"
                     /pseudo=""
     CDS             complement(14047..15157)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612110.1"
                     /locus_tag="PHA78_RS10095"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IS630 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTKEFTQTQVEELKQALKDKNNAPHHRKIQALILYSECHNLTSVA
                     KSVGFVHQTVRNLLNRYLSGGLEALLKENRGGRRRSYMTHEEEEVFLKEHLSSSLNGEF
                     VTVNTLFKAYQDKLGYATTKDVFYQLLKRHGWVKESKDSLRGEIKLTQ"
     gene            complement(15366..16055)
                     /locus_tag="PHA78_RS10100"
     CDS             complement(15366..16055)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775328.1"
                     /locus_tag="PHA78_RS10100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_024401261.1"
                     /transl_table=11
                     /translation="MKKFISRIMLVSTVVLLAACQSIQTKEDETSNTSSSSQVTTSSDQ
                     QSTSESSSETTSSSDSQTEASSTNTQAIPTVYQSVIDRYQANLGQVSEAINQDEVSSYL
                     SLLTSQGQEYSGAFYSLYDIDQNGTEELLIALNKSGDYILIDLYTQLSGENFRLVDNFR
                     NIGFEIGPDAILRPLQDGTYLFEGGGVYRIYQYNAMIPGLKRISESDTNPETSPLLELK
                     SLHWVKL"
     gene            complement(16181..16534)
                     /gene="rbfA"
                     /locus_tag="PHA78_RS10105"
     CDS             complement(16181..16534)
                     /GO_function="GO:0019843 - rRNA binding [Evidence IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="rbfA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942382.1"
                     /locus_tag="PHA78_RS10105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="WP_002942382.1"
                     /transl_table=11
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMVGDL
                     SMAKVYYTIMSNLASDNQKAQTGLEKATGTIKRELGRKLTLYKIPDLVFEKDQSIEYGN
                     KIDQMLRALDQKD"
     gene            complement(16690..19497)
                     /gene="infB"
                     /locus_tag="PHA78_RS10110"
     CDS             complement(16690..19497)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003743 - translation initiation factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="infB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896915.1"
                     /locus_tag="PHA78_RS10110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="translation initiation factor IF-2"
                     /protein_id="WP_272158113.1"
                     /transl_table=11
                     /translation="MSKKRLNEIARELGVSSKEVVAKAQELGFEVKSHASSVDEASAKR
                     LAESFGGQKSEATKVAAKVSQPEKVDETPKVETAKVEKAKETQPVVKEEVAASAVQSAP
                     HRPQSRNFKAEREARAKEQAAKRAQGQGKGGQAKSGQDRRDNRQQGQGRSNNERNDRRD
                     NRREQGSDKRKDNRFGDRRDNRDNRSGRSARFEQREAAKPAGPKIDFKARAAALKAEQN
                     AEYARTSEERFRQAQEAKKQPKKPKEIKFEEPVVESKPFVKPAPVASVPEQVAETTVDT
                     RRKKQARPDKKRDFNGDEEDGPRKQQRNRNSQNQVRNQRTSNWNNNKKNKKGKANQPAK
                     PVTERKFHELPTEFEYTAGMTVAEIAKRIKREPAEIVKKLFLMGVMATQNQSLDGDTIE
                     LLMVDYGIEAKEKVEVDNADIERFFVEEGYLNEEEMTERPPVVTIMGHVDHGKTTLLDT
                     LRNSRVATGEAGGITQHIGAYQIEEAGKKITFLDTPGHAAFTSMRARGASVTDLTILVV
                     AADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVISTAWGGES
                     EFVEISAKFNQNIDELLETVLLVAEIQELKADPTVRAIGTVIEAHLDKGKGAVATLLVQ
                     QGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNETPMAGDHFAVYED
                     EKSARAAGEERAKRALLKQRQATQRVSLENLFDTLKAGEVKSVNVIIKADVQGSVEALA
                     SSLQKIEVEGVRVNIVHSAVGAINESDITLAEASNALVIGFNVRPTAEARSQAEADDVE
                     VRLHSIIYKVIEEMEDAMKGMLDPEYEEKIIGEAIIRETFKVSKVGTIGGFMVVRGKVT
                     RDSSVRVIRDGVVVFDGKLASLKRYKDDVKEVGNAQEGGLMIENYNDLKVDDTIEAYIM
                     EEIKK"
     gene            complement(19515..19823)
                     /locus_tag="PHA78_RS10115"
     CDS             complement(19515..19823)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942377.1"
                     /locus_tag="PHA78_RS10115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="WP_029175751.1"
                     /transl_table=11
                     /translation="MDSNKRQKILNLLGLAQRAGRLVSGEDLVVEAIQKGQTKLVFLAE
                     DAAGNLSKKVTDKSHTYQVEVVTVFSTLELSAAVGKARKVLAVTDAGFTKKMRSIME"
     gene            complement(19810..20106)
                     /locus_tag="PHA78_RS10120"
     CDS             complement(19810..20106)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /locus_tag="PHA78_RS10120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YlxR family protein"
                     /protein_id="WP_002942375.1"
                     /transl_table=11
                     /translation="MAKARKIPLRKSVVSGEIIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNDEASQAKKRRVFDRSFSMEVAEEFYDELIAYVDHKIKRRELGLE"
     gene            complement(20123..21277)
                     /gene="nusA"
                     /locus_tag="PHA78_RS10125"
     CDS             complement(20123..21277)
                     /GO_process="GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /gene="nusA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194726.1"
                     /locus_tag="PHA78_RS10125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcription termination factor NusA"
                     /protein_id="WP_029175752.1"
                     /transl_table=11
                     /translation="MSKEMLEAFRILEEDMGINKADIIDAVTESLRSAYKRRYGQSESA
                     VIEFDEKKGDFHVFTVREVVDEVFDSRLEISLKDALAISSAYEMGDKIKFPEDPAEFGR
                     VAAQSAKQTIMEKMRKQKRAITFNTYKQHENEIMSGTVERFDNRFIYVNLGTIEAQLSK
                     QDQIPGEVFQSHDRIEVYVYKVEDNGRGVNVFVSRSHPEMIKRLMEQEIPEVYDGTVEI
                     MSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKITSKFHPARYDAKNDRMIPTE
                     ENIDVIEWVADEAEFIYNALAPAEVDQVLFDTEDGKHATVVVPDDKLSLAIGRRGQNVR
                     LAAHLTGFRIDIKSASEYEAIEAAQYAAEELVEEVAEEFTEEQE"
     gene            complement(21351..21821)
                     /gene="rimP"
                     /locus_tag="PHA78_RS10130"
     CDS             complement(21351..21821)
                     /GO_process="GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /gene="rimP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942369.1"
                     /locus_tag="PHA78_RS10130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribosome maturation factor RimP"
                     /protein_id="WP_002942369.1"
                     /transl_table=11
                     /translation="MSSIIELVTAAITPAIQTPYELVDVEYGKMGGDYVLSIFVDKEGG
                     ISLQDTADLSEKISPILDTIKPDPFPDQYMLEVTSPGLERPLKTADAVEKAVGKYIHVK
                     LYQAIDKIKVFEGTLLSFDGTDLIMEYMDKTRKKEVTIPYQTVAKARLAVKL"
     gene            complement(22079..22717)
                     /gene="trmB"
                     /locus_tag="PHA78_RS10135"
     CDS             complement(22079..22717)
                     /EC_number="2.1.1.33"
                     /GO_function="GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="trmB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939002.1"
                     /locus_tag="PHA78_RS10135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="WP_099870361.1"
                     /transl_table=11
                     /translation="MRVRNRKGASELLANNPQYVISNPEECKGKWAEIFGNNNPIHIEV
                     GSGKGRFVTGMAAQNPDINYIGIDIQMTVLSYALDRVLEAGLPNIKLLQVDGSSLTNYF
                     APVEIDQLYLNFSDPWPKKRHEKRRLTYKSFLDTYKEILPEKGEIHFKTDNRGLFEYSL
                     ASFSQYGMVLKQVWLDLHADGLEGNVMTEYEEKFSKKGQVIYRVEAQFQ"
ORIGIN
        1 acaagaaaat actagcaatt agtaacatat cacaaaaaag aaagccaaac ggctttcttt
       61 tttcttagct tattatttac gttttggtgg gttgtgaatc gcaaccccaa gcacatcaag
      121 gaaggcttcg tacatcactt ctgagaaggt tgggtgaccg tggatggatg ctgccacgtc
      181 gtcaactgtc aactcagatt ccatgatagt tgctgcttcg ttgatcattt cagctgcaac
      241 tggaccgatg atgtgaacac caaggatttc atggtatttc ttgtccgcaa ttacttttac
      301 gaaaccatgt gcttcgttag aagcaatggc acgaccgtta ccagtaaagc tgttgcgacc
      361 gataaggata ttttctttac cgtatttctc gatagcctgg tcttctgtca aaccaaccat
      421 agcgatttct gggtgtgtgt aaaccgctgc tggtgtgaag tccaacttcg ctttgtggtg
      481 gttaccgtga atagcatttt cagctgccac ttcacccata cggtaagcag cgtgtgccaa
      541 catcttagta ccgttgacat cacctggtgc gtagatacct gggatagatg tttcttggta
      601 ttcgttaacc ttgatacgac cgcggtccaa ttcaaggtta agattttcaa gaccagccaa
      661 ttgtggtaca cgaccgattg aaagaagggc tttttcagaa acgatttctg aaccgtcgtt
      721 caatttgatg gtcaattggt tgttggcttc aacgatttca gatacaccaa cagatgtcaa
      781 gaatttcata cctttcttag aaaggacttt ttgcaattca acagacactt cacggtccat
      841 acctggaatg atccggtcag ccatttcaac aactgttact tctgtaccgt atgatgcgta
      901 aaccaaacca agttccacac cgactacgcc accacccata acagtcagtg acttaggaat
      961 ttcacgcaag tcaagaatat catcagaagt caataccaac ttagaatcga tacctgggat
     1021 gttgatgcgt gatactttcg aacctgttgc aagaacgatg ctgcgacctt tgataacctt
     1081 gtcgccgata acaacagtct tgtcagggtt tacttgacca agaccgttga agattgttac
     1141 cttgttagct ttcaagagac cttgaacgcc accagtcaat gtcttcacaa ccttgttctt
     1201 gaagtcaact gtcttgtcca tatcaactgt gtagttggtt gaagcaaggt tgataccacg
     1261 ctcagccgca atcttcaagc cgtcaaggat ttcagcattt ttgaggtagg tcttagttgg
     1321 gatacaaccc ttgttcaagc aagtaccacc gaattctgat ttctcaacga tagcgatttt
     1381 accgcctaat tgagcaccgc gaatggcagc gtagtaacca gcaggaccac caccgacaac
     1441 aaccatgtca tattcgtctg ccgccaattc agccttagga gcttgtggag ctgctgcagg
     1501 agctacaggc acttccaaac cagctgcttt caagtcggca gttgcttgtg caacctcagc
     1561 tggagcaggt gcagcaccca cttcaactgt ttcaccttct gcaccaaggt aagcaatgac
     1621 ttctgttaca ggaaccgttg caccgttacc atgaacgatt ttcaaaagaa cacctgattc
     1681 ttctgcttcc aattccatgc ttgtcttgtc tgacatcatc tccaagataa catcaccttc
     1741 gttgacaaaa tcaccctctt gttttttcca ctcgatgatt tcgccttctt gcatatctac
     1801 accaagtttc ggcataataa tttcaattgc catagttatg atacaaagaa cgtcaaatgc
     1861 gacagaattt taggagtcca acataggatg cttgcatcca aggcggacta tctaaattcc
     1921 gaagcattta gttcgtgttc aaatgtcacg aactcgtcct acatcctttc tttatttttt
     1981 cactttacca aattgagcac aggctaaaaa cctattgaaa aagataaatc gcctcgtgcc
     2041 tcaaggcaca tcgttgattt cctattttca tacggttttc ttaacgcctt ttgcatctta
     2101 tcttaaatca acaattccaa tgggttttcc agcaagtttt tcaagtcaac catgaactta
     2161 gcaccattca taccgtcaac gatacggtgg tcaatggtca agcagagtgc catgattgga
     2221 cggatcttga tttcgccgtc gataacaact ggtgtttgaa ctgttgatgc tacaccaagg
     2281 attgctgagt ttggttggtt gatgattggg ttaaaggttt tagtaccaaa catacccaag
     2341 ttggtgatag agaaggtcga acctgacatt tcagccccct tcaacttacc agattgagcc
     2401 ttcttgatga catctttcga agccaccaca aagtcagaca agctcatctt atctgcgccg
     2461 tgaacaactg gcaccaccaa gccatcatct agacccactg cgataccaag gttgacgaac
     2521 ttgtgtaatt cgatttcttg tgcatcgtta atcaaagatg cgttcatgta acggtgttct
     2581 tctttcatca aagtacgaac aaccgcaaga ccgatcaagt ctgtaaaggt tactttcaaa
     2641 ccagtcttgt tcatgattgg ctcaaggact tgcttacgaa gtgccatgag gttggtcatg
     2701 tcaatatcgt agttaagtgt aaatgtcgga gcggtcaaat aagagttgac catacctttt
     2761 gaaatcgcct tacgcattgg gctcatcttg atgatttcaa cgccttctgg caattcttta
     2821 gctggttttt cttcagtttt cggtgctgga gcagcagttt ctacagctgc aggagcaagt
     2881 actgccaaaa catcgtcctt aacaatcttg ccattgacac ctgaacctgt aagagttgac
     2941 aggtcaacac cttggtctgc tgcaatacgg gctgcaagcg gagttgcttt tggagctgct
     3001 cccttgaagt cttcaacgtc agccttgtgg actcggccat ttgcaccagt tcctggcaca
     3061 agtcccaagt caataccaag ctcacgcgct aacttacgcg ctgctggagt agcacgtacc
     3121 ttgccgccac cttgtggctt agccgccact gctggagcaa cgataacagg cgtgcgacct
     3181 gcaggtactt cttcgatggc tgcagctggg gcaactggag tagctgacgc tccagcctca
     3241 accgtttcac cttctgcacc gatgtaggca atgacttctg ttacaggaac ggtagcaccg
     3301 tttccgtgaa caatttttaa taggacgcct gactcttctg cttccagctc catgctagtc
     3361 ttgtcagaca tcatttccaa gatgacgtcg ccttcgttga caaaatcgcc ctcttgtttt
     3421 ttccactcga tgatttcacc ttcttgcatg tccacaccga gcttaggcat aatgatttca
     3481 atagccattt ttaagatacc aagtccgaac agaaaacgaa ggagcttagg aaatcataga
     3541 aaatcctgat ttcttagcga tttatctttt ctcctaattt tccggacggg ttcaattcct
     3601 ttctttcagt ttcttacctt gtcaagaacc aaaccagact tcgctcatcg aagcggctca
     3661 attctttccc aagcattctt agtcatgcta gaatatttta tttctagcat tttagggtta
     3721 tcgtctttcc gattgctttt ctgacaaggc gatttggtgc aggcataact gacgttaggc
     3781 aggccaaatc aacacagcca gaaaagataa gcggatgacg ataagattaa cctctgttta
     3841 cttgcttgta gattgcctct ttgattttct ctacgtttgg caatactgcg ttttcaagaa
     3901 tgtttgcgta aggaactggt acatcgtctg aagcgatacg gatgattggt gcatccaagt
     3961 agtcaaaggc ttcgctttct gtgatgatcg atgcgatttc accgatgaaa ccacctgttt
     4021 tataagcatc gttgaccaag ataaccttac cagttttctt cacagattcg atgatcaatt
     4081 ctttatccaa tgggataagg gtacgtgggt caaccacttc tacgctgatg ccttctgcag
     4141 ctacttcttc agcagctttc aaggcacgct ccaacatacg accgtatgaa ataatggtta
     4201 catcagtacc ttcacgtttg atttcaccct ttccaagtgg aatgtagaaa tctgggtcca
     4261 agttaacttc ttctttttta ccgtaaagag cttttggctc caagaagata actgggttgt
     4321 tatcaaggat agatgatttc aaaagacctt ttgcatcgtt agctgtacca ggtgcgacaa
     4381 ccttgatacc tgggatgtga gtcaaccaag cttcaagaga ttgtgagtgc tgggcagcag
     4441 aaccgatacc agaacctgaa gccacacgga aggttacagg cgttttcaaa ccaccaccaa
     4501 acatgtagtt agttttggca gcttggttaa caatcgcatc aagggcaatt gttacgaagt
     4561 ccatgaaggt caagtcaacg attggacgaa gacctgtttg agctgcacca actgcagaac
     4621 cagcgattgc tgcctcagag ataggcgtat cgcgaacgcg ttttggacca aattcgtcca
     4681 acataccaac agatgtaccg aagtcaccgc cgtagatacc gacgtcttca cccatcaaga
     4741 atactttttc atccttacgc atttcttcgc tttgagccaa gttaatcgct tcacgcaagg
     4801 ccattacttt tgtttcagcc attttttact cctaatttat atcaatttat ctttactgaa
     4861 ctaaggaaaa ccaaacaatt actacgatgt aattgtttat tgtcccagct taagacacct
     4921 tagaattgta ctcgaactta aataggtagt ctaccttggt gaactaccct agtttgactt
     4981 gctatttaga acgtagtcaa actaatcaca tcacttacga cacggagact attcagccga
     5041 tattgctgaa taggcgaagt tagctccaaa catttgggaa atgtttggag gtctcccaat
     5101 agggagaact ttgttctcct cctgtaagta ggtagtccac catagtggct accgtagttt
     5161 gacttgcttc tttagagctt agtcaaactt ctgacgttaa tagttgggtt cagactagag
     5221 gcttggaaaa atagatgagc cattagtgat gtccgcatca ctagctgact ccctaatttt
     5281 tctgtgcctc tttaacgtcc tcacacccta gaattgtact cgaactaagg actgtgcgaa
     5341 tttcatgttt aactattgca gttactgcgt cgtagacaac tgtactttct tcggtttcac
     5401 ctgtgaaaat actagttgtc ttgacgaggg tgcgtctacg aaatcaaaga tttcggactt
     5461 accgcttatt ttcgctgtgt ccttttaacg ttctcgttac tagttgggtt cagactagag
     5521 gcttggaaaa atagatgagc cattagtgat gcccgcatca ctagctgact ccctaatttt
     5581 tctgcgcctc tttaacgtct tcacacccta gtctacaaac acatcctcat atgctactga
     5641 aatgtctgga tctgggcttt cttgtgcgaa tttcacagat gcttctactt gttctgcaac
     5701 ttgtgcttcg atggcatcca attcttcgtc tgtcgcaatc ttgttttctg tcaagtattt
     5761 gcggtatttc ttaagtgggt cttttgcttt ccactcgtta acttcttctt tggtacggta
     5821 aacacctgcg tcggcagttg agtgtccaaa ccagcggtat gattcaactt cgaccatagc
     5881 tggaccgtta cctgcacgaa cgtactcgat gacttcttgc attttttcat aaacggcaat
     5941 aacgtcgtta ccatcctcaa cataatgacc tggaataccg tatgctgctg cacgttggta
     6001 gaggtgagga atcttagttg aataagaaat gtctgttgag ataccgtaac ggttgttggt
     6061 gatgaagaag ataactggca aattccaaac agctgccaag ttcattgact cgtggaaaga
     6121 accttcgttt gtcgctgagt cacctgagaa ggcgataacg atgttatctg taccaaggta
     6181 ttgttgggta agggctgcac caactgcaag ggcataacca ccaccaacga taccgtttga
     6241 accgaagttc cccttttcaa cgttggccaa gtgcatagaa ccaccacgac ctttagatgt
     6301 accagttgcc ttaccagcaa gctccgccat cataccgttg atgtcaatgc cttttgcaat
     6361 aacgtgaccg tgaccacggt ggtgtgagaa gatgatgtcc tcatctgtca atccagcaat
     6421 aggtccaaca gccgcagctt cttcaccgac tgagaagtga gtcatacctt gtacgaaacc
     6481 gcgacgcact aatttgttta atttcatatc aacatcacgg atttgttgca tttttaggaa
     6541 catatccaaa tgttgttctt ttgagataga taccataatt tcctccaaag gtttttctct
     6601 ttctgtacta tgatagacca atatttcaca aatggcaagt aattgaaccg ttttcttttt
     6661 acagaaattt tcgtgaaaac cttgatttag tgcgtttttt cacaaatcct caaaagattc
     6721 actttacttg tttgaaactt ttttcacaaa ctttaaataa gcttgcacgc cgtctttctt
     6781 tctgttaata taggtacgga ggttcttatg gaattcgatt tatttcttat gatttgtaac
     6841 tacataggca ctattgcatt tgctgtttcg ggggccgtaa aaggatttaa gaaaaagtta
     6901 gatatttttg gaattagctt gctcggtatc attaccgccg ttggtggggg aattattcga
     6961 gatacaatgg ccaatcgcat tcctgccgcc ttgactgatc ctacagccat ctatttatct
     7021 ctcggagtag cgattagcat gtacttgatt gttatcaatc taaagcagga caaaccacct
     7081 ggtaagaaga tgattcattt cctttcccag acaaacctta tctttgatgc aatcggtcta
     7141 gccatcttcg ccctcattgg agccagtact ggcatctctc tccagctaaa cgctctaacc
     7201 agtggtattc tggcagcttt aacaggtgtc ggaggcggaa tcgcccgtga tttactcgtc
     7261 aatgaaacac ctattgttct taaagaagat gtctatgctg tccttgcatt tttctcagga
     7321 gtcctctatc atctttgcgt tgtaaattgg aaattaccac aaattccaac cttcatcact
     7381 atttttacca tttctttaat cattcgacta ttggtaatta aatacaaaat caatcttcca
     7441 aatatggaaa gcaaacgaaa ggtctgagtt cgtcaacaca gacctttttg tattattatt
     7501 gattaccagc caccgcgacc gccaggtcct gtcgccgtga tttgagtaat ctgctcaccg
     7561 ttaactgtca cagtacctcc tgtcaattct gctgtaccat caaagtcgaa tgctgatgtt
     7621 ggtgctgtta cagcaatagt acccccagaa atgtagatat caccgttggc atcaaaggca
     7681 tccgtatctc cactacctac agctactttc aagtcaccgc cagttacctt gatgaagatt
     7741 tctgatgacg ttgtacttgc cgcattaata gcatcatctg aaccatagac atcaattgta
     7801 ccaccgttga tagtgatatt agttccttcc aaggcttcta ctgattctga tactgtaatg
     7861 gtacctccgt caattgtcaa agccgtctcc gctttaatac catcatcacc tgcttttaca
     7921 gtaatttcac cacctgtgat agttgtataa cctttggtag tatctgtatc atttgtagac
     7981 ttgataccat caccacctgc tgtgacattg attgtaccac cattgattgt caatgaatcc
     8041 ttgccacgga taccatcatc cactgcagtg acggtaatgt ttcctgaatt cacgacaagg
     8101 tcatctgtcg atacgatgcc atcttggaag ttgccttcaa cggtcaggct accatttcct
     8161 gtaatggtca aatcagcttc aacatggata gccccttcaa tattggtgtc tgtatgattg
     8221 ctggtatctt tcactgtatt cgtcgtacca tctttgattt ccaattcaac attgtcagca
     8281 ttaataacat tgattgctgc agtatctgaa cttgaaatct cagcacctgc tagaatgatg
     8341 cgaacattgg catctgtttc aaccgttaca ccagcagttg ttgaacctgt caaaatgtag
     8401 gtaccaccct ctgtaatttt caagccatcg tttgaaagtg ttacttctgt agtaggaagg
     8461 gctgaccagt caatcgaaga tgatgatgaa cttgagtcag atgatgtgct attgctggaa
     8521 gtagttgatg cacttgattg acttgtagct gcagaacttg atgttgtcat tgaactagaa
     8581 gttgatgaac atgccaccaa gataccgata ctcatcaacg tgacacccga ataaagtagt
     8641 tttttaaaat ttgttttcat aaatagattc cttttctttc ttaggaggtt tttggatacc
     8701 ttcctgatat gctcttagtt taccttccct acctaaaaga aagattaaag attaccaaaa
     8761 gaaaacttaa agtctgattt ttaccagtat gcttgtacta cctaggctcc ttccactacc
     8821 gtccattcaa cattcgttcc atgattaccc ttcccctcaa ggaataccct attaaaattg
     8881 ggtcccctga tgtagactgc ctgaatttga acttacgtcc tttcctctct atttgaaaat
     8941 gaaaagaata aaaaggaaaa caaagttatg atgccaaata gtaaataatt actccttata
     9001 ccaaagttat ctgcgaaaat accagctaga aagtccgata ccataaaact aatggaaata
     9061 aataaattat agaccgacca tgatactgct ctattttttt ctatcgaact attaaacata
     9121 gaataaaaat gattattata acttgaattg agaacacgca tcaataaaaa taatacaatt
     9181 tctatgaata cattcgtttg aaaaaacata aaaatagcta gcactggtag taataaactg
     9241 atttcaaact tcatttttag gtaactcccc aaagccatag ctatattaaa catgaatagt
     9301 actatgccca acatatctag tgaaagtccc tgttcattta gaaaaatgcc tgcataggaa
     9361 ttgctgatca taattagagt tgagaatgct actcctaaca gtagtaaata ccatggaatc
     9421 gttttaacat catcaaagct aaaaaatctt gaatcattag gtaattcatt ttttatttca
     9481 ggtaattgta tcacatttaa gaggctgaaa atgacaaata caatcgaaat aataatcgga
     9541 taaatataat tcctattcag tagataggga gatataattg taataatcgc tataaaaatg
     9601 tattttaccg tattgaggta tttcaaaaaa gattgatata ctagctcgtt gccaattaat
     9661 tcaaaattat aagcattaag aacgcctgaa gataaggatt ctgacaagcc aaaaaatatc
     9721 gctgaaatat atattatttt tgattgtcct aacagtaagc aagatagggc taaagttaat
     9781 aacaaatttg ataaaatcaa aattttctta tagccaaact tacttgaaag aaaacttaaa
     9841 ggaatatcaa aaactgagcc gcataactca gtaatcactg ataaagtagc tatttctgtg
     9901 aaagagaagc ccagatgctt taagagcaat acacctataa aatagtaggg caatccggac
     9961 aaaaatatat tcatcatgta taagttcaaa aatcttttac tcataattgg caaactgagt
    10021 ctctaaaata ttctggactc ttctccttga tcaagttaat atagcagcca ccctcgcaaa
    10081 tttttaacaa tccacaagat aaacacttag aattcttcgt tctaaaagaa cgaatccctc
    10141 catacaacgg atcatcatac caaacatcta acaaatcttt ttcaaaggca ttctgcttag
    10201 tttgattaac tcctaaaaaa gcaatgcagg gcaagatatc cccattagac attatttcca
    10261 tcttagtata ttttgcacga catccataat acatttcgtc aaactctgaa aattcaattg
    10321 aattatttat caactctgga taagcggtga aaagatgaca tccctcagta gcaaaattta
    10381 aatttgcttc acgttgagtt atataatctg taacatactc attcaacctt ctcaaatcag
    10441 ccaaatcgta ttttttcttt attttcgtat atcctgttac ctcagaataa ttagctactg
    10501 aaaacctatc tattttattc tctatacaaa aatcaaccaa ttctataatt tgctcatagc
    10561 tttgctttgt atacactgca ttaattctac atttttttcc aacctcatta aagtacttcg
    10621 ctaattttat ttgtctatca ggtctcaccc ccattaattc aaaatttaat ttagaatcta
    10681 aagtctgcaa agataaaacc ggtgtaatat atttagattt agctagaatt tctactgtac
    10741 ttttctttat taattgggca ttagttgtta tagtagtctt tatctttagt tcctcacaag
    10801 ctatcaacaa attatcaata tcaaaatatc tagtcggttc ccctcctaaa attgaaacac
    10861 ttaacactcc attatctttt gcttggcgca aaattctttc ccaatcttta gcaggtttgg
    10921 catttctatc ttcacgattt gctaaaaaac aaaaaccaca ttttaaatca cagtacatac
    10981 tggggtatat tactagttca agcggaaaac tcagtatgtt atgttttttt aattttgcta
    11041 catgctttct cgcattttga agagtctcgt aaggattgtt cgatgaatcc tcaatattat
    11101 tatcagaata gatatttaat gataatgctc tctctagttt ccctatctca atttcttttt
    11161 taaaaaaaga agttgcaatt tcaataccat gattttgaac taaatataga aagaaagcct
    11221 cagtctcatc taactctatt ctttcaaaat ttgttttgtt tattaaaatt ccaccaaact
    11281 tttctaatct aatactattc aaaaaacaaa aactaaccta taatagattt atgaaactta
    11341 ctatcgaaca aacgaaagaa ttaaaaactt atttgaaaga taaaacctat tctccatttc
    11401 atagacgact tcaagttatc ttgttcagag cagaaggtct tagctataag gaaatcacta
    11461 acctcatcgg ctattcaaag tatacaatct ggtccttaca gcgcaagtac gaacttgagg
    11521 ggatttcagc tctagtaaga gaaacgcgag gtggacggaa ccgtcaatat ttaacccttc
    11581 aagaagagga agcgtttcta aaagaacagt taacagcctc actaaatggc gaatttgtga
    11641 cgataaactc tctctatgaa gcttatcaga aacgggttgg acaccctacg accaaggaag
    11701 gattctatgc cattcttaaa cgccatggtt ggcgcaaagt gacgccaaga ccagaacacc
    11761 ctaaaaaagc agacgccgaa acgattctag cgtctaaaaa taaaatcttc attcacgaaa
    11821 acaggaaagc gcttcaagaa tagtcgtcgc tatcataaag tcaggctaat gtatcaagat
    11881 gaggcgggtt tcggtcggat cagtaaaatt gggaaggcct gggcaccaaa aggggtgaga
    11941 ccgcatgtac atagtcacta tattcgtgag tatcgctatt gctatggtgc tgttgatgcc
    12001 catacaggag agtccttctt cattatcgct gggggctgta atacagattg gatgaatgtt
    12061 tttctcaaac aactatctga agcttatcct gacgattata ttttattagt gatggacaat
    12121 gccgtttggc ataaatcaag taccttagag aaaccacata atattggttt tgagtttatt
    12181 cctccctata ctcctgaaat gaatccaatt gaacaagttt gggctgagat tcgaaagaga
    12241 gggtttaaga ataaagcttt taaaacacta gacgatgtga taaacaagct tcaagaagta
    12301 atacgagagt tagattggtc tattttaaaa ccaattgtta gtagacaatg gtttaaaaac
    12361 acttgactgg tttgcttttg atttttgttg agtataaata aaatatcttc tgaaattgtc
    12421 ctcatcttga acacctcttt aaaaaagcag aggaaaataa cctctgctta acctatgtat
    12481 aaattacttt atacatgcca accgtcgcct tttgccatag cactagactc aaggactttt
    12541 tcaagttctt ttgacataat tgctactcct ttcgaacgtg atactgtaag tatattcttt
    12601 taaatcaatt acaataaaat gttcccatat atgccaatta actattttct gttaaaattt
    12661 ttttcaaatg ttcttcataa atctgtgcca catgatcact acctgctaat ttcatcgctc
    12721 caatacactt cctcatttcc acaatcgcaa atttacttcc agttttgcga tagcgataaa
    12781 gattttgagc atagagaaaa acaagtctct cataaatttc tgtttcgata aaaaagcact
    12841 gtttcaattg cttctcaaaa tacaaagcat ctataagatt ttgccgttcg atacaggtga
    12901 tataggcatt aagtaacatc gtagaaataa gacgacgatt attagggatt tctttaaaaa
    12961 agtctgaccg tctagacatt tccctcgcta atactatgaa aacatcatat ttcaagacat
    13021 ctaaagtatt catgaaaatc aaaagttcat aatagcccca gtattccaca ctaaataaat
    13081 agtcagttaa ttcatctaag tctttatcat tgtaataatt ttcccctgac aaatcttgca
    13141 ggcgaatctt taataaaatg atattgatgt gataaaattt ctcccgttta tcctccgatt
    13201 ctatctgaga ataaagaagt tttttcatgc cttcgacatc acgagtagat acataataac
    13261 gtacttttga caggagctca tttagttcat ctctatgaaa atcatgaacc gcatacataa
    13321 attcatcgat cggcatgtta atttcatcca atatgagtaa gaactttgaa atcgttaagt
    13381 cagtctctcc tttctcaaat cgagagagct gagacgttga gataccaacc tttgcgacat
    13441 cttttaattt taatcctctc gattctcgaa actttttaaa aatttctcca aaatttttca
    13501 tctctcctcc tccatcacgc atatatggga ataatttttg tttgatccta taatagcata
    13561 caataaagaa aaataaaagt gaggattatc acatgaaaaa ataccattta ttaactcttc
    13621 tttttgttat tttagaagga attatcgtca tcggtgtagg ataaaatcga gtaagagcta
    13681 ctcaccaccc cctctcacac caccggtaaa cggcggttca actaattttt aacgcatgtc
    13741 gttctagata ataatctaag taagaagcca gtccatgttt agcgaggact ggttttgata
    13801 tggcacattt caataccgac ttctgagcca ctaatggata acggtcaccc tatccagata
    13861 ctttattcgc tatatacgcc ttatactaaa ttagaatcaa atttcacaaa ccgttccggc
    13921 atagctacca acaactattc attacatttt gcaaagtact gaaactagaa aatttttagg
    13981 tagtttatca ttaaatttac atatctgata taaaaatttc caattatact cattttgatt
    14041 ttatactcag ttaaaatcaa aaatagcgga agtccagtct ctatctacaa ttgatttgag
    14101 ttgataagcg gttaaggttt gaataacctc ttgaagttta tcgattacct catttaaggt
    14161 cctaaatact ttattcttga aaccaagttt acgaatctca gtccagactt gctcaatagg
    14221 attcatttca ggtgtgtagg gtggaatgaa ggtaaattca atattcttag ggatatttaa
    14281 ggtctgagat ttatgccaga tggcattatc catgactaaa acaatataat cttctggata
    14341 agctgccgat agttggcgta gaaatgcatt catccaatca ctattacatc cgcctgctat
    14401 gatgaaaaac gagtcgcctg tatgggcatc cacagctcca taacaatagc ggtactcacg
    14461 aatatgatga cttgctacgt gaggacgata acctttagga gaccaacacg agccaagttt
    14521 actgatacgc ccaaaacccg cctcatcttg atacataagg cggatttttt gatattcttt
    14581 tccatcaata aagcgcttac tcgttctctc ctcgaataaa gattttattt ttagacgcta
    14641 aaatggtttc ggcgtctgct tttttcggat attggggacg tgggctaact tttgttgctt
    14701 actgcgtaag ctttatttcc cctctcaaag aatcttttga ttctttgacc catccatgac
    14761 gtttcaatag ttggtaaaaa acgtctttag tcgttgcgta accaagttta tcttgatagg
    14821 ctttaaagag ggtgttaaca gtaacgaatt ctccattcaa agaggaagag agatgctctt
    14881 taaggaaaac ttcttcctcc tcatgcgtca tatacgaacg gcggcgacca ccacgatttt
    14941 cctttaagag ggcttctaag ccaccactta gatagcgatt caataagttt cggactgtct
    15001 gatggacaaa acctactgat ttagctacgg atgttaaatt atggcattca gaataaagaa
    15061 tgagtgcctg gatttttcta tgatgcggag cattattttt atctttaagt gcttgcttta
    15121 attcttcaac ttgtgtctgg gtaaattctt ttgtcataat actatcatat cgctattttt
    15181 gatttttgtt aagtattagg tctcgacctc acgatagtca gacttgggag tcgctattgg
    15241 gttcatgggc tgtgggtgcc cacagaggac ttgctcctcc gatttacgac ataccgatgt
    15301 actcaaagtg cttaggaact acaaaaggcc gggaaaccca gcctaggaat aatcattgat
    15361 aaaatctata gcttaaccca atgcaagctt ttcaactcaa gcaaggggga tgtttcagga
    15421 ttagtatccg attcagaaat ccgtttcaat cctggaatca ttgcattgta ctgataaatc
    15481 cggtatactc cacccccttc aaataaatag gttccatcct gtaagggacg aagaatggca
    15541 tccgggccaa tttcaaaacc aatatttcgg aaattatcta ctaaacgaaa attctcccca
    15601 gatagctgcg tgtaaagatc aatgaggata tagtcaccag atttattcaa ggctatgagc
    15661 aattcctctg tcccattttg atcaatatcg tataggctat aaaatgctcc gctgtattct
    15721 tggccttgac tcgtcagtaa acttagataa ctactaacct cgtcctgatt aatcgcttca
    15781 gaaacctgac ctaaattggc ttggtaacga tcgataacgg actggtacac agtcggtatc
    15841 gcctgagtat ttgtagaaga tgcttcggtt tgtgagtctg aactagatgt agtctctgag
    15901 gaagactctg aggtagattg ttggtccgaa ctagttgtaa cttggctcga tgaactagta
    15961 ttggaagttt catcctcctt ggtctgaatg gattgacatg ctgctaataa cacaaccgtg
    16021 gataccaaca ttatacgact aataaacttt ttcataactt cctcctgtgc tctatctttg
    16081 gtcttagtat aacatctttc cgagggcttg taaacgccac catatttgga caaagcatcc
    16141 gagccagaaa aagccgaatg tttccatccg acttttgttg ttaatctttc tgatcaagag
    16201 cacgcaacat ttggtcaatt ttattgccgt actcaattga ttggtctttt tcaaagacca
    16261 aatccggaat tttataaaga gttaacttac gaccaagttc tctcttaatg gttccagtcg
    16321 ctttttcaag acccgtttgt gccttttgat tatcggatgc caaattactc atgattgtgt
    16381 agtaaacctt ggccattgac aaatcgccga ccatctgaac atctgtaatg gtcactccct
    16441 gcacacgtgg atcacgaact ttcttttgta aaatctcatt gacttcgcgc ttgatttcca
    16501 tcccgacacg gtctgtacga aaatgattcg ccatattctt tcctttctta gatgatagaa
    16561 aagctgagtt tccccagctt gaataatcca agtagattaa aaactattgc tttaaaatct
    16621 actaaaatct attaaattat cacttcctcg acaaaatcac ttgtctatga ctttgacagt
    16681 gagaaaatat tattttttga tttcttccat gatgtaagct tcaatggtat catcaacttt
    16741 caagtcgttg tagttctcaa tcatcaaacc accctcttgg gcattaccaa cttctttcac
    16801 gtcatcttta tagcgtttca aactagctag tttaccatca aatactacaa caccatcacg
    16861 gataactcga acacttgaat cacgggtaac cttaccacgt acgaccatga aaccaccgat
    16921 cgttccaact ttggatacct tgaaggtttc acgaatgatt gcctcaccaa tgattttttc
    16981 ttcatattct ggatcaagca tacctttcat ggcatcttcc atctcttcga taaccttgta
    17041 aatgatgctg tgaagacgta cttcaacgtc atctgcttca gcttggctac gcgcttcagc
    17101 tgttggacga acgttgaaac caatcacaag agcatttgaa gcttccgcaa gagtaatatc
    17161 tgattcattg atagcaccaa ctgcagagtg gacgatattg acacgtactc cctcaacttc
    17221 aatcttttga agcgatgatg caagagcttc aactgaacct tgtacgtcag ccttgataat
    17281 cacattaact gacttaacct cacctgcttt aagggtatca aagaggtttt caagactaac
    17341 tcgttgcgtt gcttgacgct gtttaagaag agcacgttta gcacgttctt caccggcagc
    17401 acgcgcagat ttttcatctt catagaccgc gaaatggtcg ccagccattg gcgtttcatt
    17461 caaaccagta atagataccg gtgtagatgg tccagccacc ttaacacgac gaccaaggtc
    17521 gtttgtcatg gcacgaacac gtccgaaggt atttccgaca acgattgggt cttgaacatt
    17581 aagtgtccct tgttgaacga gaagggttgc aaccgcacct ttccctttgt ccaaatgtgc
    17641 ttcgataacc gtaccgattg cacgaacagt tgggtctgcc ttcagttctt ggatttcagc
    17701 gaccaaaaga acagtttcca acaattcatc aatgttttgg ttaaacttag ctgagatttc
    17761 tacaaattca gattctccac cccaagcggt tgagataaca ccgtgctcag ccaattcacc
    17821 gataacacgc tctgggtttg cacctggctt gtcaatcttg ttgatagcta caatgattgg
    17881 cacattagcg gcttttgagt ggttgatagc ctcaatcgtt tgtggcatga caccatcatc
    17941 tgcagcaacg actaggatgg tcaagtcggt aacagatgca ccacgtgcac gcatagaagt
    18001 aaaggccgcg tgtcctggag tatccaagaa ggtaattttc ttaccagctt cctcaatttg
    18061 gtaggcaccg atatgctgtg tgatacctcc agcttcccca gtagcaacac gagaattacg
    18121 tagggtatcc aacaaggttg ttttaccatg gtcaacgtgt cccatgatag tcacaacagg
    18181 tgggcgttct gtcatctctt cttcattgag gtaaccctct tctacgaaga aacgctcaat
    18241 atctgcgtta tcgacctcta ccttttcttt cgcctcaata ccataatcaa ccatgaggag
    18301 ttcgatagta tctccatcca aagattggtt ttgagtcgcc ataactccca taaggaagag
    18361 ttttttcaca atttcagcag gttcacgttt gattcgtttt gcaatttctg cgacggtcat
    18421 accagcagtg tattcaaatt cagttggcaa ttcgtggaac ttgcgttctg tgacaggttt
    18481 ggcaggttgg tttgccttgc cttttttatt tttcttattg ttattccagt tacttgttct
    18541 ttgatttctc acttgatttt gactatttcg atttctttgt tgtttccgtg gaccatcttc
    18601 ttcgtcacca ttaaagtcac gttttttatc tggtcgagct tgtttcttac gacgggtatc
    18661 tacagtagtt tctgcaactt gctctggtac cgatgcaaca ggtgcaggct tcacaaatgg
    18721 tttgctttcc acaaccggtt cttcaaactt aatttctttt ggcttcttag gttgcttttt
    18781 agcttcctga gcctgacgaa aacgttcttc actggtacga gcatactccg cattttgttc
    18841 tgctttcaaa gcagcagcac gcgctttgaa gtcaatttta ggtcctgctg gttttgcagc
    18901 ctctctttgt tcaaagcgag ctgaccgacc tgaacggtta tcacgattat cgcgacggtc
    18961 cccaaaacga ttgtcctttc gtttatctga accctgttca cgtctattat cgcggcgatc
    19021 atttcgctca ttgtttgaac gtccctgacc ttgttgacgg ttgtcacgac ggtcctgacc
    19081 agatttagct tgaccacctt ttccttgacc ctgagctcgc ttagcagcct gctctttggc
    19141 ccgtgcttca cgttctgcct taaagtttcg actctgtgga cgatgtggag ctgattgtac
    19201 tgcgcttgcc gcaacttctt cttttactac tggctgtgtt tccttagctt tttctacctt
    19261 agctgtttcc acttttggag tttcatcaac cttttcaggc tggctaactt ttgccgcaac
    19321 tttagttgcc tctgattttt gtcccccaaa gctttctgca aggcgtttag cacttgcttc
    19381 atctacgctt gaagcatgac ttttgacttc aaaacccaat tcttgagcct tagcaacaac
    19441 ttccttactg cttacaccta attcacgggc tatttcattc aatctcttct tagacaatgc
    19501 cttgtcctcc tgttctattc cataatagac ctcatcttct ttgtaaatcc agcgtctgtc
    19561 actgcaagaa cttttctagc cttgccgaca gctgcactca attccagtgt tgaaaacact
    19621 gttacaactt ctacttgata ggtatgactt ttatctgtta cttttttact taaatttcca
    19681 gcagcatctt cggctaaaaa caccaacttt gtctgccctt tttgaatagc ttcaacaacc
    19741 aggtcctcac ccgaaaccag gcgaccagct cgctgggcta aacctaataa atttaagatt
    19801 ttctgtctct tattcgagtc caagttctct cctcttgatc ttatgatcaa cataggcaat
    19861 taattcatcg taaaattctt cggccacttc catactaaag gaacgatcga agacacgacg
    19921 tttcttagct tggcttgcct catcattgtc aagcttgata taagctccac gaccatttgc
    19981 cttgcctgtt ggatcgataa atacttgacc ttctttattt tttacaatac ggagcaaatc
    20041 ccgtttgtcg atgatttcac cggacaccac agacttgcgc aagggtattt ttctagcttt
    20101 tgccatggct gctccttttg ttctattctt gttcttctgt aaattcttcc gcgacttctt
    20161 ctacaagctc ttctgccgca tattgagccg cctcaattgc ttcatattct gatgcagatt
    20221 tgatgtcgat acggaatccg gtcaaatggg ctgctaaacg aacgttctga ccacgacgtc
    20281 caattgctag tgacaattta tcatctggca caacgactgt agcatgcttc ccatcttccg
    20341 tgtcaaacaa tacttggtca acttcagcag gagcgagagc attgtagata aattccgctt
    20401 catctgctac ccactcgata acgtcaatat tttcctccgt aggaatcatg cggtcatttt
    20461 tagcatcata acgagctggg tggaacttac tggtgatttt cttgatattt gaaccaccac
    20521 ggccaacgat tgtaccgatg gcatctacgt ttggattatg gctacgaaca gccactttcg
    20581 ttcggtctcc agcttcacgg gcaacactca tgatttcaac tgttccatcg tatacttctg
    20641 gaatttcctg ttccatgaga cgtttgatca tttctggatg gctacggctg acaaatacgt
    20701 taacaccacg accattgtct tctaccttgt agacatagac ttcaatacga tcatgagatt
    20761 ggaaaacctc accaggaatt tggtcttgtt ttgacaattg tgcttcaatc gtaccaaggt
    20821 tgacatagat aaagcgatta tcaaaacgct ctaccgtacc tgacataatc tcattttcat
    20881 gttgcttgta ggtattgaag gtaatggcac gcttttgttt gcgcattttt tccatgatgg
    20941 tctgcttagc tgattgggct gctacacgac caaattccgc tggatcttct gggaatttaa
    21001 ttttgtcacc catttcataa gctgatgaaa tagccaaggc atcttttaga ctaatttcta
    21061 gtcggctatc aaatacttca tctactactt cacgaacagt aaatacatgg aaatcacctt
    21121 ttttctcgtc aaattcgatc actgctgatt ctgattgacc ataacggcgt ttataagctg
    21181 aacgaagcga ctctgtaact gcatcaatga tatccgcttt gttaataccc atgtcttcct
    21241 ctaaaatacg gaaggcttct agcatttctt tactcatgtt gttttccttt tgcgctcaaa
    21301 aggtcctttc ttaaagtcta atatctttat aaaatactca tgaaagagca ttataactta
    21361 acagccaaac gggccttagc caccgtctgg taaggaatag tcacttcctt cttacgagtt
    21421 ttatccatat actccataat caggtctgtt ccatcaaagg agagcaacgt tccttcaaaa
    21481 accttgattt tatcaattgc ctgatagagc ttgacatgga tgtactttcc aaccgccttc
    21541 tcaacagcat ctgccgtttt taaaggacgc tccaaacctg gacttgttac ctccagcatg
    21601 tattggtctg gaaatgggtc tggcttgata gtgtccaaaa tcggactgat cttttcggat
    21661 aaatctgccg tatcttgaag ggaaattcca ccctccttat cgacaaaaat cgataggaca
    21721 tagtcaccgc ccattttacc atattccaca tccaccaact cgtaaggagt ttgaatagcg
    21781 ggggtaattg ctgctgtgac caattcaata attgatgaca taaacacctc ctatttttat
    21841 agtcgctaga aatacattac tcaaatagtt cgcactatcc aggactctct atttcctttg
    21901 acaataaact cccttgtact atccttcatt ctatatacag aaatccgtgt acagggaaag
    21961 ggttgactga cgccaacccc ttttctcatt attcacttac actattctat catatctatc
    22021 cctatttgta aaggaaaaag gtctctgtta gacctctcct cattttccac taagggaatt
    22081 attgaaactg tgcttccaca cggtagataa cctggccttt tttggagaat ttctcctcat
    22141 actctgtcat aacgttgcct tccaaaccat ccgcatgcaa atctagccaa acttgcttca
    22201 agaccatgcc atattgagaa aaactagcca ggctatactc aaacagacca cgattatctg
    22261 ttttgaagtg gatttctccc ttctcaggta ggatttcctt gtaggtatct aagaatgact
    22321 tgtaggtcaa acggcgtttc tcatgacgtt tcttaggcca tggatcagaa aaattcagat
    22381 aaagctgatc tatttctacc ggtgcaaaat agttggtcaa actcgaacca tccacctgca
    22441 ataattttat atttggtaag ccagcttcaa gcacacggtc caaggcatag cttaacacgg
    22501 tcatctgaat atcaatacca atatagttaa tatctggatt ttgcgcagcc ataccagtga
    22561 caaagcgacc tttaccagaa ccaacttcta tgtggatagg attattgttt ccaaaaatct
    22621 ctgcccattt ccccttacac tcctctggat tggagataac atactgggga ttgtttgcta
    22681 gaagctcact cgctccctta cgatttctaa ctctcatact tccttataga aactctgacg
    22741 gaattgccgt agagcataaa tttctttatt tgcagccaaa acattgtagc tttctacatg
    22801 cttagctatt tggtttagat agccaagctg gccataccaa taaaccttat ttaatactgt
    22861 gctgttatat ttgtagccat aagcccgaag ccactcttcc caggactgac gaggaatata
    22921 atgcgtcaaa atataggcaa catccaacat ccgatccgtt acacaagcgg tctcccaatc
    22981 tgtcaaatac accaaaccag acgtcgtttc tacccagtta ctatgatgca aatctccgtg
    23041 aacaaatgtt gccacctctt gacggaatct tggtagatta ttcaataaat cttgacagat
    23101 agattgcaga taagaattct gtcccaatct agttggagcc tctttttgcc aacgataaac
    23161 caaatcctga ggttccatat aggtataatt catctgcaaa gcctgattga gcaaaatgcg
    23221 agaatagtgc attctcacca gtatttgacg aatctgttta ctagtcatat cttgacgctc
    23281 caaggtacga ccattcaacc actcctgctc tacacgatgc cccattccta cttcacgatt
    23341 tgctgacaaa acgggtggtg taatttgctc acgcgcaaga gcagacacta tcggaggcat
    23401 ctcatacttc acaaagactg gcgttccgtc tgaccgtaga cctttaaacg ctttgccact
    23461 atttcctgca atagactgta attgtagccc actggtatca a
//
