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Overview
1.1
1.2
1.3
1.4
1.5

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP116604.1 (Streptococcus sp. HN38)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1.1 | RiPP-like | 241,691 | 259,421 |
Region 1.2 | lanthipeptide-class-iv | 314,912 | 337,587 |
Region 1.3 | terpene-precursor,T3PKS | 537,033 | 578,198 |
Region 1.4 | lanthipeptide-class-i | 985,523 | 1,011,534 | Medium | suicin 90-1330 | ribosomal:RiPP
Region 1.5 | RaS-RiPP | 2,064,140 | 2,087,640 | High | streptide | ribosomal:RiPP

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1.1 | RiPP-like | 241,691 | 259,421 |
Region 1.2 | lanthipeptide-class-iv | 314,912 | 337,587 |
Region 1.3 | terpene-precursor,T3PKS | 537,033 | 578,198 |
Region 1.4 | lanthipeptide-class-i | 985,523 | 1,011,534 | Medium | suicin 90-1330 | ribosomal:RiPP
Region 1.5 | RaS-RiPP | 2,064,140 | 2,087,640 | High | streptide | ribosomal:RiPP

No secondary metabolite regions were found in these records:
  NZ_CP116605.1 (Streptococcus sp. HN38)

Compact view
NZ_CP116604.1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 241,691 - 259,421 nt. (total: 17,731 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
No tailoring functions detected.
Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000624.3 |  | 0.53 | ribosomal | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0000619.3 |  | 0.52 | ribosomal | gassericin T | Lactobacillus gasseri
BGC0001602.3 |  | 0.52 | ribosomal | gassericin-T | Lactobacillus gasseri
BGC0001388.3 |  | 0.52 | ribosomal | gassericin E | Lactobacillus gasseri
BGC0000617.5 |  | 0.51 | ribosomal | coagulin | Bacillus coagulans
BGC0002579.2 |  | 0.50 | ribosomal | carnobacteriocin XY | Carnobacterium maltaromaticum
BGC0000558.5 |  | 0.49 | ribosomal | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000623.3 |  | 0.48 | ribosomal | plantaricin W α, plantaricin W β | Lactobacillus plantarum
BGC0002577.2 |  | 0.48 | ribosomal | lactococcin G | Lactococcus lactis
BGC0001862.4 |  | 0.45 | ribosomal | pallidocin | Aeribacillus pallidus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000624.3 |  | 0.53 | ribosomal | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0000619.3 |  | 0.52 | ribosomal | gassericin T | Lactobacillus gasseri
BGC0001602.3 |  | 0.52 | ribosomal | gassericin-T | Lactobacillus gasseri
BGC0001388.3 |  | 0.52 | ribosomal | gassericin E | Lactobacillus gasseri
BGC0000617.5 |  | 0.51 | ribosomal | coagulin | Bacillus coagulans
BGC0002579.2 |  | 0.50 | ribosomal | carnobacteriocin XY | Carnobacterium maltaromaticum
BGC0000558.5 |  | 0.49 | ribosomal | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000623.3 |  | 0.48 | ribosomal | plantaricin W α, plantaricin W β | Lactobacillus plantarum
BGC0002577.2 |  | 0.48 | ribosomal | lactococcin G | Lactococcus lactis
BGC0001862.4 |  | 0.45 | ribosomal | pallidocin | Aeribacillus pallidus

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.22 out of 27.78
Confidence: medium
Additional weak hits (1):
ArgR
Description: Regulator of arginine biosynthesis genes
Species: Streptomyces coelicolor
Score: 17.61 out of 20.01
Confidence: weak
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria

NZ_CP116604.1 - Region 2 - lanthipeptide-class-iv
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 314,912 - 337,587 nt. (total: 22,676 nt) Show pHMM detection rules used
lanthipeptide-class-iv: (cds(LANC_like and Pkinase) and not micKC)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Lanthipeptides
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Lyases: cyclase
PHA78_RS01640: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-iv | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000519.4 |  | 0.47 | ribosomal | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0002700.2 |  | 0.45 | ribosomal | bacinapeptin | Bacillus nakamurai
BGC0000554.4 |  | 0.44 | ribosomal | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001887.3 |  | 0.44 | ribosomal | huazacin | Bacillus thuringiensis serovar huazhongensis BGSC 4BD1
BGC0000553.3 |  | 0.43 | ribosomal | SRO15-2212 | Streptomyces filamentosus NRRL 15998
BGC0000558.5 |  | 0.43 | ribosomal | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0002306.2 |  | 0.42 | ribosomal | freyrasin | Paenibacillus polymyxa ATCC 842
BGC0001555.4 |  | 0.41 | ribosomal | colicin V | Escherichia coli chi7122
BGC0002699.2 |  | 0.40 | ribosomal | nostolysamide A, nostolysamide B | Nostoc punctiforme PCC 73102
BGC0001639.3 |  | 0.40 | ribosomal | klebsidin | Klebsiella pneumoniae

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000519.4 |  | 0.47 | ribosomal | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0002700.2 |  | 0.45 | ribosomal | bacinapeptin | Bacillus nakamurai
BGC0000554.4 |  | 0.44 | ribosomal | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001887.3 |  | 0.44 | ribosomal | huazacin | Bacillus thuringiensis serovar huazhongensis BGSC 4BD1
BGC0000553.3 |  | 0.43 | ribosomal | SRO15-2212 | Streptomyces filamentosus NRRL 15998
BGC0000558.5 |  | 0.43 | ribosomal | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0002306.2 |  | 0.42 | ribosomal | freyrasin | Paenibacillus polymyxa ATCC 842
BGC0001555.4 |  | 0.41 | ribosomal | colicin V | Escherichia coli chi7122
BGC0002699.2 |  | 0.40 | ribosomal | nostolysamide A, nostolysamide B | Nostoc punctiforme PCC 73102
BGC0001639.3 |  | 0.40 | ribosomal | klebsidin | Klebsiella pneumoniae

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.
Lanthipeptides - No core peptides found.
Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 25.99 out of 29.25
Confidence: strong
ToxT
Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.31 out of 18.57
Confidence: strong
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.23 out of 27.78
Confidence: medium
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.98 out of 27.78
Confidence: medium
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 21.89 out of 27.78
Confidence: medium
PerR
Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 24.68 out of 28.14
Confidence: medium
CcpA
Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 17.98 out of 20.97
Confidence: medium
Additional weak hits (5):
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.63 out of 26.06
Confidence: weak
PerR
Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 22.68 out of 28.14
Confidence: weak
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 22.38 out of 29.25
Confidence: weak
HexR
Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 23.95 out of 31.73
Confidence: weak
OsdR
Description: Development and stress management regulator
Species: Streptomyces coelicolor
Score: 19.98 out of 30.12
Confidence: weak
Lanthipeptides
TFBS Finder
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.
No core peptides found.
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CcpA | Catabolite control protein A
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
PerR | Peroxide regulator
SypG | Regulator of biofilm formation and host colonization
ToxT | Regulator of MSHA biosynthesis

NZ_CP116604.1 - Region 3 - T3PKS,terpene-precursor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 537,033 - 578,198 nt. (total: 41,166 nt) Show pHMM detection rules used
terpene-precursor: (PT_FPPS_like and not PT_HPP)
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: oxidoreductase reductase
PHA78_RS02785: hydroxymethylglutaryl-CoA reductase

smcogs
  SMCOG1187: hydroxymethylglutaryl-CoA reductase

PHA78_RS02820: oxidoreductase

smcogs
  SMCOG1079: oxidoreductase

Transferases: acetyltransferase methyltransferase
PHA78_RS02710: isoprenylcysteine carboxyl methyltransferase

smcogs
  SMCOG1150: isoprenylcysteine carboxyl methyltransferase

PHA78_RS02795: acetyl-CoA acetyltransferase

smcogs
  SMCOG1124: acetyl-CoA acetyltransferase

Hydrolases: deacetylase
PHA78_RS02810: polysaccharide deacetylase

smcogs
  SMCOG1235: polysaccharide deacetylase

Isomerases: mutase
PHA78_RS02800: phosphoglycerate mutase

smcogs
  SMCOG1101: phosphoglycerate mutase

Ligases: synthase synthetase
PHA78_RS02730: Polyprenyl synthetase

smcogs
  SMCOG1182: Polyprenyl synthetase

PHA78_RS02790: hydroxymethylglutaryl-CoA synthase

smcogs
  SMCOG1043: hydroxymethylglutaryl-CoA synthase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene-precursor | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0002397.2 |  |  | 0.36 | terpene | astallatene | Arabidopsis thaliana
BGC0002400.2 |  |  | 0.33 | terpene | boleracene | Brassica oleracea var. oleracea
BGC0002398.2 |  |  | 0.26 | terpene | (-)-ent-quiannulatene | Arabidopsis thaliana
BGC0001605.3 |  |  | 0.25 | terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0000550.3 |  |  | 0.24 | ribosomal | salivaricin G32 | Streptococcus salivarius
BGC0001456.3 |  |  | 0.23 | terpene | isorenieratene | Streptomyces argillaceus
BGC0001529.5 |  |  | 0.22 | other (other) | benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K | Streptomyces sp. RI18
BGC0000668.5 |  |  | 0.22 | other (other), terpene | 12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole | Hapalosiphon welwitschii UTEX B 1830
BGC0000633.3 |  |  | 0.22 | terpene | carotenoid | Streptomyces avermitilis
BGC0001227.3 |  |  | 0.22 | terpene | isorenieratene | Streptomyces collinus Tu 365

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002397.2 |  | 0.53 | terpene | astallatene | Arabidopsis thaliana
BGC0002400.2 |  | 0.50 | terpene | boleracene | Brassica oleracea var. oleracea
BGC0000866.5 |  | 0.48 | other (other) | polyhydroxyalkanoate | Burkholderia sp. DSM 9242
BGC0000867.3 |  | 0.46 | other (other) | polyhydroxyalkanoic acids | Ectothiorhodospira shaposhnikovii
BGC0000205.3 |  | 0.44 | PKS | bryostatin | Candidatus Endobugula sertula
BGC0002398.2 |  | 0.44 | terpene | (-)-ent-quiannulatene | Arabidopsis thaliana
BGC0001605.3 |  | 0.43 | terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0002561.3 |  | 0.42 | other (other) | phenazine SA, phenazine SB, phenazine SC | Streptomyces sp.
BGC0001529.5 |  | 0.41 | other (other) | benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K | Streptomyces sp. RI18
BGC0000668.5 |  | 0.41 | other (other), terpene | 12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole | Hapalosiphon welwitschii UTEX B 1830

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
sesquiterpene precursor |  | FPP | C15 | acyclic | PP

Genes with terpene domains:
PHA78_RS02730: PT_FPPS_like
Domain 1 (25 - 272): Prenyltransferase; Farnesyl diphosphate synthase like
Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:
  DMAPP, IPP → FPP

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
ToxT
Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57
Confidence: strong
ToxT
Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57
Confidence: strong
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.64 out of 26.06
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.40 out of 26.06
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.70 out of 26.06
Confidence: medium
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
DMAPP | Dimethylallyl diphosphate
FPP | Farnesyl diphosphate
IPP | Isopentenyl diphosphate
PP | Diphosphate

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
MogR | Repressor of flagellar motility genes
ToxT | Regulator of MSHA biosynthesis

NZ_CP116604.1 - Region 4 - lanthipeptide-class-i
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 985,523 - 1,011,534 nt. (total: 26,012 nt) Show pHMM detection rules used
lanthipeptide-class-i: (((Lant_dehydr_N or Lant_dehydr_C) and cds(LANC_like and not Pkinase)) and not (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Lanthipeptides
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Hydrolases: protease
PHA78_RS04870: alkaline serine protease, subtilase family

smcogs
  SMCOG1075: alkaline serine protease, subtilase family

Lyases: cyclase dehydratase
PHA78_RS04910: Lantibiotic dehydratase domain protein

smcogs
  SMCOG1155: Lantibiotic dehydratase domain protein

PHA78_RS04920: Lanthionine synthetase C family protein

smcogs
  SMCOG1140: Lanthionine synthetase C family protein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-i | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001789.3 |  | 0.75 | ribosomal | suicin 90-1330 | Streptococcus suis
BGC0000537.3 |  | 0.75 | ribosomal | nisin U | Streptococcus uberis
BGC0000538.3 |  | 0.68 | ribosomal | nisin Z | Lactococcus lactis
BGC0000535.4 |  | 0.68 | ribosomal | nisin A | Lactococcus lactis subsp. lactis
BGC0000536.3 |  | 0.65 | ribosomal | nisin Q | Lactococcus lactis
BGC0000506.4 |  | 0.57 | ribosomal | entianin | Bacillus subtilis subsp. spizizenii
BGC0000541.5 |  | 0.57 | ribosomal | paenicidin A | Paenibacillus polymyxa
BGC0000542.3 |  | 0.57 | ribosomal | paenicidin B | Paenibacillus terrae
BGC0000559.4 |  | 0.55 | ribosomal | subtilin | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0000556.5 |  | 0.54 | ribosomal | streptin | Streptococcus pyogenes

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001789.3 |  | 0.75 | ribosomal | suicin 90-1330 | Streptococcus suis
BGC0000537.3 |  | 0.75 | ribosomal | nisin U | Streptococcus uberis
BGC0000538.3 |  | 0.68 | ribosomal | nisin Z | Lactococcus lactis
BGC0000535.4 |  | 0.68 | ribosomal | nisin A | Lactococcus lactis subsp. lactis
BGC0000536.3 |  | 0.65 | ribosomal | nisin Q | Lactococcus lactis
BGC0000506.4 |  | 0.57 | ribosomal | entianin | Bacillus subtilis subsp. spizizenii
BGC0000541.5 |  | 0.57 | ribosomal | paenicidin A | Paenibacillus polymyxa
BGC0000542.3 |  | 0.57 | ribosomal | paenicidin B | Paenibacillus terrae
BGC0000559.4 |  | 0.55 | ribosomal | subtilin | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0000556.5 |  | 0.54 | ribosomal | streptin | Streptococcus pyogenes

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for PHA78_RS04910

PHA78_RS04905
Leader:
MQNNDFNLDLVSTSKEKKQGASPR
Core:
I T S I S L C T A G C I T G R I M G C H K T P T V S C N C H
Core with dehydrations:
I Dhb Dha I Dha L Cys Dhb A G Cys I Dhb G R I M G Cys H K Dhb P Dhb V Dha Cys N Cys H

#### antiSMASH-DB 4.0 matches for PHA78_RS04905

100.0%
NZ_CP116604.1 and 2 others:
NZ_JAFFHI010000008.1 Lanthipeptides: JN541_RS08535_lanthipeptide NZ_JAFFHJ010000004.1 Lanthipeptides: JN542_RS06245_lanthipeptide
Lanthipeptides: PHA78_RS04905_lanthipeptide
1
I T S I S L C T A G C I T G R I M G C H K T P T V S C N C H
30
I T S I S L C T A G C I T G R I M G C H K T P T V S C N C H
1
I T S I S L C T A G C I T G R I M G C H K T P T V S C N C H
30
58.8%
NC_013656.1 and 20 others:
NC_020450.1 Lanthipeptides: LILO_RS03015_lanthipeptide NZ_CP009472.1 Lanthipeptides: LG36_RS03420_lanthipeptide NZ_CP010050.1 Lanthipeptides: QI18_RS03300_lanthipeptide NZ_CP015903.1 Lanthipeptides: LLUC08_RS03255_lanthipeptide NZ_CP024954.1 Lanthipeptides: CV702_RS02990_lanthipeptide NZ_CP066300.1 Lanthipeptides: LacL0098_RS03205_lanthipeptide NZ_CP098790.1 Lanthipeptides: M5C73_RS03405_lanthipeptide NZ_JAALEQ010000006.1 Lanthipeptides: HFD15_RS10120_lanthipeptide NZ_JAJONJ010000005.1 Lanthipeptides: LSG16_RS07195_lanthipeptide NZ_JAQDWM010000007.1 Lanthipeptides: PGU01_RS08180_lanthipeptide NZ_JAQDXV010000018.1 Lanthipeptides: PGT80_RS11850_lanthipeptide NZ_JAQDYA010000007.1 Lanthipeptides: PGT72_RS09560_lanthipeptide NZ_JAQDYA010000007.1 Lanthipeptides: PGT72_RS09560_lanthipeptide NZ_JAQEIZ010000019.1 Lanthipeptides: PGX18_RS12025_lanthipeptide NZ_JAQEOU010000022.1 Lanthipeptides: PGV42_RS12330_lanthipeptide NZ_JAQEOV010000015.1 Lanthipeptides: PGW09_RS10765_lanthipeptide NZ_MTJP01000006.1 Lanthipeptides: BW151_RS03795_lanthipeptide NZ_MTJR01000005.1 Lanthipeptides: BW153_RS02980_lanthipeptide NZ_MTJS01000002.1 Lanthipeptides: BW154_RS09850_lanthipeptide NZ_RAGL01000022.1 Lanthipeptides: D6108_RS11395_lanthipeptide
Lanthipeptides: LLKF_RS13210_lanthipeptide
1
I T S I S L C T A G C I T G R I M G C H-K T P T V S C N C H
30
I T S I S L C T G C T G +M G C+ K T T +C+ H
1
I T S I S L C T P G C K T G A L M G C N M K T A T C N C S I H
31
58.8%
NZ_CP065984.1 and 2 others:
NZ_CP095737.1 Lanthipeptides: MXM90_RS03205_lanthipeptide NZ_JAQDXJ010000021.1 Lanthipeptides: PGU19_RS11740_lanthipeptide
Lanthipeptides: I6I21_RS02785_lanthipeptide
1
I T S I S L C T A G C I T G R I M G C H-K T P T V S C N C H
30
I T S I S L C T G C T G +M G C+ K T T C+ H
1
I T S I S L C T P G C K T G A L M G C N M K T A T C H C S I H
31
with 87 more sequence matches
Only the first 10 are displayed here.
56.7%
NZ_CP024974.1 and 1 other:
NZ_JAIMDQ010000006.1 Lanthipeptides: K6V44_RS04045_lanthipeptide
Lanthipeptides: CVO91_RS06555_lanthipeptide
1
I T S I S L C T A G C I T G R I M G C H K T P T V S C N C H
30
+T S I S L C T G C T G +M C T +C C H
1
V T S I S L C T P G C K T G I L M T C-A I K T A T C G C H
29
55.9%
NZ_CP009913.1 and 1 other:
NZ_CP009913.1 Lanthipeptides: SSAL8618_RS00810_lanthipeptide
Lanthipeptides: SSAL8618_RS00815_lanthipeptide
1
I T S I S L C T A G C I T G R I M G C H K T P T V S C N C H
30
I T S S L C T G C I T G +M G C H ++ C N H
1
I T S Y S L C T P G C I T G V L M G C H-I Q S I G C N V H
29
55.9%
NZ_CP090412.1 and 3 others:
NZ_QSTB01000004.1 Lanthipeptides: DXC22_RS03785_lanthipeptide NZ_VSTZ01000009.1 Lanthipeptides: FYK98_RS07445_lanthipeptide NZ_VSTZ01000009.1 Lanthipeptides: FYK98_RS07445_lanthipeptide
Lanthipeptides: LZF92_RS09890_lanthipeptide
1
I T S I S L C T A G C I T G R I M G C H K T P T V S C N C H
30
I T S S L C T G C T G +M G C T S C C H
1
I T S Y S L C T P G C K T G A L M G C-T M K T A S C G C H
29
55.9%
NZ_FBTD01000003.1:
Lanthipeptides: PB1E_RS03075_lanthipeptide
1
I T S I S L C T A G C I T G R I M G C H K T P T V S C N C H
30
I T S+S L C T G C T G +M G C+ T S C C H
1
I T S V S L C T P G C K T G A L M G C N-M K T A S C G C H
29
55.9%
NZ_LR793265.1:
Lanthipeptides: HV392_RS09825_lanthipeptide
1
I T S I S L C T A G C I T G R I M G C H K T P T V S C N C H
30
I T S S L C T G C I T G R+M G C + + C N H
1
I T S Y S L C T P G C I T G R L M G C-Q F Q S A G C N V H
29
54.3%
NZ_FNDP01000013.1:
Lanthipeptides: BLP54_RS11230_lanthipeptide
1
I T S I S L C T A G C I T G R I M G C-H K T P T V S C N C H
30
I T S S L C T G C+T G +M G C +K T T +C+ H
3
I T S K S L C T P G C V T G V L M G C N N K T A T C N C S V H
33
53.3%
NZ_CP086149.1 and 13 others:
NZ_CP086149.1 Lanthipeptides: LL127_RS22600_lanthipeptide NZ_CP086149.1 Lanthipeptides: LL127_RS22595_lanthipeptide NZ_CP086149.1 Lanthipeptides: LL127_RS22590_lanthipeptide NZ_CP086149.1 Lanthipeptides: LL127_RS22585_lanthipeptide NZ_CP086149.1 Lanthipeptides: LL127_RS22580_lanthipeptide NZ_CP086149.1 Lanthipeptides: LL127_RS22575_lanthipeptide NZ_CP086149.1 Lanthipeptides: LL127_RS22570_lanthipeptide NZ_CP087100.1 Lanthipeptides: LOR37_RS23225_lanthipeptide NZ_CP087100.1 Lanthipeptides: LOR37_RS23220_lanthipeptide NZ_CP087100.1 Lanthipeptides: LOR37_RS23215_lanthipeptide NZ_CP087100.1 Lanthipeptides: LOR37_RS23210_lanthipeptide NZ_CP087100.1 Lanthipeptides: LOR37_RS23205_lanthipeptide NZ_CP087100.1 Lanthipeptides: LOR37_RS23200_lanthipeptide
Lanthipeptides: LL127_RS22605_lanthipeptide
5
S L C T A G C I T G R I M G C H K
21
S L C T A G C I T G R I M G C+K
2
S L C T A G C I T G R I M G C N K
18
53.1%
NZ_CP059471.1 and 3 others:
NZ_FNZW01000001.1 Lanthipeptides: BMZ61_RS02110_lanthipeptide NZ_FOYC01000001.1 Lanthipeptides: BMZ88_RS03370_lanthipeptide NZ_KE384124.1 Lanthipeptides: G597_RS0106700_lanthipeptide
Lanthipeptides: H1R75_RS06635_lanthipeptide
1
I T S I S L C T A G C I T G R I M G C H K T P T V S C N C H
30
I T S S L C T G C T G +M C T +C C H
1
I T S K S L C T P G C K T G A L M T C-P I K T A T C G C H
29
53.1%
NZ_FNDP01000013.1:
Lanthipeptides: BLP54_RS11235_lanthipeptide
1
I T S I S L C T A G C I T G R I M G C H K T P T V S
26
S I S L C T G C T G +M G C H K P+ S
1
F K S I S L C T P G C P T G I L M G C H K C P S G S
26
52.9%
NZ_JADNFO010000025.1:
Lanthipeptides: I2C89_RS09745_lanthipeptide
1
I T S I S L C T A G C I T G R I M G C H K T P T V S C N C
29
I T S S L C T G C T G +M C H T +C N C
1
I T S Y S L C T P G C K T G V L M A C H-L K T A T C N C
28

#### MIBiG 4.0 matches for PHA78_RS04905

58.8%
BGC0000535.4 (ADJ56352.1):
Lanthipeptide: nisin A
1
I T S I S L C T A G C I T G R I M G C H-K T P T V S C N C H
30
I T S I S L C T G C T G +M G C+ K T T C+ H
1
I T S I S L C T P G C K T G A L M G C N M K T A T C H C S I H
31
13.3%
BGC0002111.3 (EVG22_32245)and 1 other:
BGC0002111.3 (multiple genes) Lanthipeptide: andalusicin A or andalusicin B
Lanthipeptide: andalusicin A or andalusicin B
24
T V S C N C
29
T+S N C
18
T I S N N C
23
10.8%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
12
I T G R I M G
18
+T G I+G
5
V T G L I L G
11

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
No hits above weak threshold.
Weak hits (3):
HgtR
Description: Hydrogen-dependent regulator
Species: Geobacter sulfurreducens PCA
Score: 28.30 out of 36.54
Confidence: weak
ClgR
Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 20.26 out of 30.22
Confidence: weak
ClgR
Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 20.44 out of 30.22
Confidence: weak
Lanthipeptides
RREFinder
TFBS Finder
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

PHA78_RS04905 - Class I
  Cleavage pHMM score: 21.80
  RODEO score: 27
  Monoisotopic mass: 2962.4 Da
  Molecular weight: 2964.5 Da
  Number of bridges: 5
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2982.5 Da N = 1
    3000.6 Da N = 2
    3018.6 Da N = 3

RRE predictions
RREfinder results sidepanel.

lanthipeptide-class-i protocluster (985522...1011534)
PHA78_RS04910
  RRE type: Lanthipeptide_LanB_RRE
  Location: 143 - 229
  Score: 67.0

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---

NZ_CP116604.1 - Region 5 - RaS-RiPP
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,064,140 - 2,087,640 nt. (total: 23,501 nt) Show pHMM detection rules used
RaS-RiPP: (PF04055 and TIGR01716)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: oxidoreductase
PHA78_RS10035: pyridine nucleotide-disulfide oxidoreductase

smcogs
  SMCOG1175: pyridine nucleotide-disulfide oxidoreductase

Ligases: synthase
PHA78_RS10045: 1-deoxy-D-xylulose-5-phosphate synthase

smcogs
  SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RaS-RiPP | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001209.3 |  | 0.83 | ribosomal | streptide | Streptococcus thermophilus LMD-9
BGC0001535.3 |  | 0.55 | other (other) | branched-chain fatty acids | Streptomyces filamentosus
BGC0001929.2 |  | 0.45 | ribosomal | WGK | Streptococcus ferus
BGC0002583.2 |  | 0.44 | ribosomal | tryglysin B | Streptococcus mutans UA159
BGC0001736.3 |  | 0.34 | NRPS | pepteridine A, pepteridine B | Photorhabdus laumondii subsp. laumondii TTO1
BGC0002716.2 |  | 0.33 | NRPS | gamexpeptide A, gamexpeptide B, gamexpeptide E, luminmide B, luminmide D, luminmide E, luminmide F, luminmide G | Photorhabdus laumondii subsp. laumondii
BGC0001567.4 |  | 0.32 | NRPS | cysteoamide | Streptomyces lincolnensis
BGC0001594.3 |  | 0.32 | other (other) | fischerindole L | Fischerella muscicola UTEX 1829
BGC0001628.4 |  | 0.31 | NRPS | JBIR-78, JBIR-95 | Kibdelosporangium sp. AK-AA56
BGC0001501.5 |  | 0.31 | other (other) | ambiguine P | Fischerella sp. TAU

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001209.3 |  | 0.83 | ribosomal | streptide | Streptococcus thermophilus LMD-9
BGC0001535.3 |  | 0.55 | other (other) | branched-chain fatty acids | Streptomyces filamentosus
BGC0001929.2 |  | 0.45 | ribosomal | WGK | Streptococcus ferus
BGC0002583.2 |  | 0.44 | ribosomal | tryglysin B | Streptococcus mutans UA159
BGC0001736.3 |  | 0.34 | NRPS | pepteridine A, pepteridine B | Photorhabdus laumondii subsp. laumondii TTO1
BGC0002716.2 |  | 0.33 | NRPS | gamexpeptide A, gamexpeptide B, gamexpeptide E, luminmide B, luminmide D, luminmide E, luminmide F, luminmide G | Photorhabdus laumondii subsp. laumondii
BGC0001567.4 |  | 0.32 | NRPS | cysteoamide | Streptomyces lincolnensis
BGC0001594.3 |  | 0.32 | other (other) | fischerindole L | Fischerella muscicola UTEX 1829
BGC0001628.4 |  | 0.31 | NRPS | JBIR-78, JBIR-95 | Kibdelosporangium sp. AK-AA56
BGC0001501.5 |  | 0.31 | other (other) | ambiguine P | Fischerella sp. TAU

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
ToxT
Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57
Confidence: strong
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 23.60 out of 30.25
Confidence: medium
CRP
Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 17.40 out of 19.26
Confidence: medium
Additional weak hits (2):
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.45 out of 30.25
Confidence: weak
LuxO
Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 22.66 out of 26.12
Confidence: weak
RREFinder
TFBS Finder
RRE predictions
RREfinder results sidepanel.

RaS-RiPP protocluster (2064139...2087640)
PHA78_RS10070
  RRE type: Streptide_RRE
  Location: 1 - 80
  Score: 77.2

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CRP | Cyclic AMP receptor protein
ColR | Phenol-responsive regulator
ToxT | Regulator of MSHA biosynthesis