GCF_028325765.1 - 7 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NZ_JAQMJT010000011.1 (Streptococcus salivarius)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 2.1	RiPP-like	52,254	69,280

NZ_JAQMJT010000001.1 (Streptococcus salivarius)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 11.1	terpene-precursor	56,921	77,793
Region 11.2	T3PKS	366,567	407,742

NZ_JAQMJT010000004.1 (Streptococcus salivarius)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 33.1	RiPP-like	74,012	86,108

NZ_JAQMJT010000006.1 (Streptococcus salivarius)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 35.1	lanthipeptide-class-iv	1	13,922
Region 35.2	lanthipeptide-class-ii	23,411	46,191	High	suicin 65	ribosomal:RiPP
Region 35.3	phosphonate	56,920	73,288

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 2.1	RiPP-like	52,254	69,280
Region 11.1	terpene-precursor	56,921	77,793
Region 11.2	T3PKS	366,567	407,742
Region 33.1	RiPP-like	74,012	86,108
Region 35.1	lanthipeptide-class-iv	1	13,922
Region 35.2	lanthipeptide-class-ii	23,411	46,191	High	suicin 65	ribosomal:RiPP
Region 35.3	phosphonate	56,920	73,288

No secondary metabolite regions were found in these records:: NZ_JAQMJT010000010.1 (Streptococcus salivarius); NZ_JAQMJT010000012.1 (Streptococcus salivarius); NZ_JAQMJT010000013.1 (Streptococcus salivarius); NZ_JAQMJT010000014.1 (Streptococcus salivarius); NZ_JAQMJT010000015.1 (Streptococcus salivarius); NZ_JAQMJT010000016.1 (Streptococcus salivarius); NZ_JAQMJT010000017.1 (Streptococcus salivarius); NZ_JAQMJT010000018.1 (Streptococcus salivarius); NZ_JAQMJT010000019.1 (Streptococcus salivarius); NZ_JAQMJT010000020.1 (Streptococcus salivarius); NZ_JAQMJT010000021.1 (Streptococcus salivarius); NZ_JAQMJT010000022.1 (Streptococcus salivarius); NZ_JAQMJT010000023.1 (Streptococcus salivarius); NZ_JAQMJT010000024.1 (Streptococcus salivarius); NZ_JAQMJT010000025.1 (Streptococcus salivarius); NZ_JAQMJT010000026.1 (Streptococcus salivarius); NZ_JAQMJT010000027.1 (Streptococcus salivarius); NZ_JAQMJT010000028.1 (Streptococcus salivarius); NZ_JAQMJT010000029.1 (Streptococcus salivarius); NZ_JAQMJT010000002.1 (Streptococcus salivarius); NZ_JAQMJT010000030.1 (Streptococcus salivarius); NZ_JAQMJT010000031.1 (Streptococcus salivarius); NZ_JAQMJT010000032.1 (Streptococcus salivarius); NZ_JAQMJT010000033.1 (Streptococcus salivarius); NZ_JAQMJT010000034.1 (Streptococcus salivarius); NZ_JAQMJT010000035.1 (Streptococcus salivarius); NZ_JAQMJT010000036.1 (Streptococcus salivarius); NZ_JAQMJT010000037.1 (Streptococcus salivarius); NZ_JAQMJT010000038.1 (Streptococcus salivarius); NZ_JAQMJT010000003.1 (Streptococcus salivarius); NZ_JAQMJT010000005.1 (Streptococcus salivarius); NZ_JAQMJT010000007.1 (Streptococcus salivarius); NZ_JAQMJT010000008.1 (Streptococcus salivarius); NZ_JAQMJT010000009.1 (Streptococcus salivarius)

Compact view

NZ_JAQMJT010000011.1 - Region 1 - RiPP-like

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Location: 52,254 - 69,280 nt. (total: 17,027 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

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Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Hydrolases: esterase

PNU26_RS09140: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase

smcogs: SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002306.2	0.44	ribosomal	freyrasin	Paenibacillus polymyxa ATCC 842
BGC0000623.3	0.43	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0001843.2	0.43	NRPS	tridecaptin M	Paenibacillus sp. M-152
BGC0001229.4	0.42	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0000624.3	0.42	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0000449.5	0.42	NRPS	tridecaptin	Paenibacillus terrae
BGC0001555.4	0.42	ribosomal	colicin V	Escherichia coli chi7122
BGC0000571.3	0.41	ribosomal	burhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000513.3	0.41	ribosomal	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0000519.4	0.41	ribosomal	labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3	Actinomadura namibiensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002306.2	0.44	ribosomal	freyrasin	Paenibacillus polymyxa ATCC 842
BGC0000623.3	0.43	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0001843.2	0.43	NRPS	tridecaptin M	Paenibacillus sp. M-152
BGC0001229.4	0.42	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0000624.3	0.42	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0000449.5	0.42	NRPS	tridecaptin	Paenibacillus terrae
BGC0001555.4	0.42	ribosomal	colicin V	Escherichia coli chi7122
BGC0000571.3	0.41	ribosomal	burhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000513.3	0.41	ribosomal	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0000519.4	0.41	ribosomal	labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3	Actinomadura namibiensis

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

AfsQ1

Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 17.28 out of 19.52

Confidence: medium

Additional weak hits (8):

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 22.57 out of 32.74

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 23.48 out of 32.74

Confidence: weak

OsdR

Description: Development and stress management regulator
Species: Streptomyces coelicolor
Score: 19.59 out of 30.12

Confidence: weak

AfsQ1

Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 16.94 out of 19.52

Confidence: weak

AfsQ1

Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 16.94 out of 19.52

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 22.94 out of 29.38

Confidence: weak

PerR

Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 22.70 out of 28.14

Confidence: weak

AfsQ1

Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 16.94 out of 19.52

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
AfsQ1	Two-component system AfsQ1-Q2, activator of antibiotic production

NZ_JAQMJT010000001.1 - Region 1 - terpene-precursor

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Location: 56,921 - 77,793 nt. (total: 20,873 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

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Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

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Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: methyltransferase

PNU26_RS00345: methyltransferase

smcogs: SMCOG1089: methyltransferase

Isomerases: mutase

PNU26_RS00245: phosphoglycerate mutase

smcogs: SMCOG1101: phosphoglycerate mutase

Ligases: synthase synthetase

PNU26_RS00240: 2-isopropylmalate synthase

smcogs: SMCOG1271: 2-isopropylmalate synthase

PNU26_RS00295: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002398.2	0.38	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0001605.3	0.38	terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0000633.3	0.37	terpene	carotenoid	Streptomyces avermitilis
BGC0001456.3	0.36	terpene	isorenieratene	Streptomyces argillaceus
BGC0000286.3	0.35	PKS	viguiepinol	Streptomyces sp. KO-3988
BGC0001529.5	0.34	other (other)	benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K	Streptomyces sp. RI18
BGC0000648.3	0.34	terpene	carotenoid	Myxococcus xanthus
BGC0000904.5	0.34	other (other)	FR-900098	Streptomyces rubellomurinus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002398.2	0.38	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0001605.3	0.38	terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0000633.3	0.37	terpene	carotenoid	Streptomyces avermitilis
BGC0001456.3	0.36	terpene	isorenieratene	Streptomyces argillaceus
BGC0000286.3	0.35	PKS	viguiepinol	Streptomyces sp. KO-3988
BGC0001529.5	0.34	other (other)	benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K	Streptomyces sp. RI18
BGC0000648.3	0.34	terpene	carotenoid	Myxococcus xanthus
BGC0000904.5	0.34	other (other)	FR-900098	Streptomyces rubellomurinus

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor		FPP	C15	acyclic	PP

Genes with terpene domains:

PNU26_RS00295: PT_FPPS_like

Domain 1 (26 - 276): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:: IPP, DMAPP → FPP

Transcription Factor Binding Sites

No hits above weak threshold.

Weak hits (2):

CopR

Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 23.60 out of 30.97

Confidence: weak

ZuR variant 2

Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 26.34 out of 33.14

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description

NZ_JAQMJT010000001.1 - Region 2 - T3PKS

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Location: 366,567 - 407,742 nt. (total: 41,176 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

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Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

NRPS/PKS domains

Gene/CDS overview

Filter:

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: reductase

PNU26_RS01940: hydroxymethylglutaryl-CoA reductase

smcogs: SMCOG1187: hydroxymethylglutaryl-CoA reductase

Transferases: glycosyltransferase transferase

PNU26_RS01980: glycosyl transferase group 1

smcogs: SMCOG1045: glycosyl transferase group 1

PNU26_RS01985: glycosyl transferase group 1

smcogs: SMCOG1045: glycosyl transferase group 1

PNU26_RS02010: glucose-1-phosphate adenylyl/thymidylyltransferase

smcogs: SMCOG1064: glucose-1-phosphate adenylyl/thymidylyltransferase

Ligases: synthase

PNU26_RS01935: hydroxymethylglutaryl-CoA synthase

smcogs: SMCOG1043: hydroxymethylglutaryl-CoA synthase

Translocases: permease

PNU26_RS01905: phenylalanine-specific permease

smcogs: SMCOG1038: phenylalanine-specific permease

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000255.5	0.41	PKS	pederin	Uncultured bacterium
BGC0002561.3	0.40	other (other)	phenazine SA, phenazine SB, phenazine SC	Streptomyces sp.
BGC0000205.3	0.40	PKS	bryostatin	Candidatus Endobugula sertula
BGC0000016.4	0.38	other (other)	amphotericin B	Streptomyces nodosus
BGC0001080.5	0.37	other (phenazine)	endophenazine A, endophenazine B	Streptomyces anulatus
BGC0000781.3	0.37	saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000286.3	0.36	PKS	viguiepinol	Streptomyces sp. KO-3988
BGC0002594.2	0.34	PKS	orcinol, orsellinic acid	Fusarium graminearum PH-1
BGC0000896.5	0.34	other (other)	cycloserine	Streptomyces lavendulae subsp. lavendulae
BGC0000872.5	0.33	other (other)	A-90289 A, A-90289 B	Streptomyces sp. SANK 60405

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000255.5	0.41	PKS	pederin	Uncultured bacterium
BGC0002561.3	0.40	other (other)	phenazine SA, phenazine SB, phenazine SC	Streptomyces sp.
BGC0000205.3	0.40	PKS	bryostatin	Candidatus Endobugula sertula
BGC0000016.4	0.38	other (other)	amphotericin B	Streptomyces nodosus
BGC0001080.5	0.37	other (phenazine)	endophenazine A, endophenazine B	Streptomyces anulatus
BGC0000781.3	0.37	saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000286.3	0.36	PKS	viguiepinol	Streptomyces sp. KO-3988
BGC0002594.2	0.34	PKS	orcinol, orsellinic acid	Fusarium graminearum PH-1
BGC0000896.5	0.34	other (other)	cycloserine	Streptomyces lavendulae subsp. lavendulae
BGC0000872.5	0.33	other (other)	A-90289 A, A-90289 B	Streptomyces sp. SANK 60405

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.31 out of 18.57

Confidence: strong

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.31 out of 18.57

Confidence: strong

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 21.27 out of 25.88

Confidence: medium

CRP

Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 17.19 out of 19.26

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.53 out of 26.06

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.67 out of 26.06

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 24.52 out of 28.19

Confidence: strong

Additional weak hits (2):

RicR

Description: Copper-responsive regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 21.43 out of 32.93

Confidence: weak

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.16 out of 30.25

Confidence: weak

Detailed domain annotation

Selected features only

Show module domains

TFBS Finder

TFBS definitions

Regulator	Description
CRP	Cyclic AMP receptor protein
MogR	Repressor of flagellar motility genes
PsrA	Oleic acid responsive regulator
ToxT	Regulator of MSHA biosynthesis
ZuR variant 1	Zinc-responsive repressor

NZ_JAQMJT010000004.1 - Region 1 - RiPP-like

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Location: 74,012 - 86,108 nt. (total: 12,097 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

No tailoring functions detected.

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000617.5	0.44	ribosomal	coagulin	Bacillus coagulans
BGC0002579.2	0.43	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0001555.4	0.41	ribosomal	colicin V	Escherichia coli chi7122
BGC0002577.2	0.39	ribosomal	lactococcin G	Lactococcus lactis
BGC0000619.3	0.39	ribosomal	gassericin T	Lactobacillus gasseri
BGC0001602.3	0.39	ribosomal	gassericin-T	Lactobacillus gasseri
BGC0000588.5	0.39	ribosomal	microcin L	Escherichia coli
BGC0001388.3	0.39	ribosomal	gassericin E	Lactobacillus gasseri
BGC0000624.3	0.37	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0001861.4	0.34	ribosomal	bacillicin BAG2O	Bacillus cereus BAG2O-1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000617.5	0.44	ribosomal	coagulin	Bacillus coagulans
BGC0002579.2	0.43	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0001555.4	0.41	ribosomal	colicin V	Escherichia coli chi7122
BGC0002577.2	0.39	ribosomal	lactococcin G	Lactococcus lactis
BGC0000619.3	0.39	ribosomal	gassericin T	Lactobacillus gasseri
BGC0001602.3	0.39	ribosomal	gassericin-T	Lactobacillus gasseri
BGC0000588.5	0.39	ribosomal	microcin L	Escherichia coli
BGC0001388.3	0.39	ribosomal	gassericin E	Lactobacillus gasseri
BGC0000624.3	0.37	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0001861.4	0.34	ribosomal	bacillicin BAG2O	Bacillus cereus BAG2O-1

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 25.38 out of 27.78

Confidence: strong

LexA variant 3

Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 24.75 out of 32.93

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.01 out of 26.06

Confidence: medium

Additional weak hits (1):

AfsQ1

Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 16.94 out of 19.52

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
LexA variant 3	Repressor of DNA damage response
MogR	Repressor of flagellar motility genes

NZ_JAQMJT010000006.1 - Region 1 - lanthipeptide-class-iv

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Location: 1 - 13,922 nt. (total: 13,922 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-iv: (cds(LANC_like and Pkinase) and not micKC)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

No tailoring functions detected.

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002700.2	0.49	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0002111.3	0.46	ribosomal	andalusicin A, andalusicin B	Bacillus thuringiensis serovar andalousiensis NRRL B-23139
BGC0000551.5	0.45	ribosomal	SapB	Streptomyces coelicolor A3(2)
BGC0000519.4	0.44	ribosomal	labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3	Actinomadura namibiensis
BGC0000496.5	0.42	ribosomal	AmfS	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000518.3	0.41	ribosomal	informatipeptin	Streptomyces viridochromogenes DSM 40736
BGC0001639.3	0.41	ribosomal	klebsidin	Klebsiella pneumoniae
BGC0000513.3	0.40	ribosomal	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0000539.5	0.39	ribosomal	nukacin ISK-1	Staphylococcus warneri
BGC0000521.3	0.39	ribosomal	lacticin 481	Lactococcus lactis subsp. lactis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002700.2	0.49	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0002111.3	0.46	ribosomal	andalusicin A, andalusicin B	Bacillus thuringiensis serovar andalousiensis NRRL B-23139
BGC0000551.5	0.45	ribosomal	SapB	Streptomyces coelicolor A3(2)
BGC0000519.4	0.44	ribosomal	labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3	Actinomadura namibiensis
BGC0000496.5	0.42	ribosomal	AmfS	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000518.3	0.41	ribosomal	informatipeptin	Streptomyces viridochromogenes DSM 40736
BGC0001639.3	0.41	ribosomal	klebsidin	Klebsiella pneumoniae
BGC0000513.3	0.40	ribosomal	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0000539.5	0.39	ribosomal	nukacin ISK-1	Staphylococcus warneri
BGC0000521.3	0.39	ribosomal	lacticin 481	Lactococcus lactis subsp. lactis

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Transcription Factor Binding Sites

No hits above weak threshold.

Weak hits (2):

ClgR

Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 20.57 out of 30.22

Confidence: weak

NuR

Description: Nickel-responsive regulator
Species: Streptomyces coelicolor
Score: 21.73 out of 30.98

Confidence: weak

Lanthipeptides

TFBS Finder

Core peptide predictions

No core peptides found.

TFBS definitions

Regulator	Description

NZ_JAQMJT010000006.1 - Region 2 - lanthipeptide-class-ii

Download region GenBank file

Download region SVG

Location: 23,411 - 46,191 nt. (total: 22,781 nt) Show pHMM detection rules used

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Lyases: cyclase

PNU26_RS06595: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

PNU26_RS06625: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000550.3	1.00	ribosomal	salivaricin G32	Streptococcus salivarius
BGC0001788.3	0.84	ribosomal	suicin 65	Streptococcus suis
BGC0000557.5	0.79	ribosomal	streptococcin A-FF22	Streptococcus pyogenes
BGC0000562.3	0.75	ribosomal	variacin	Kocuria varians
BGC0000526.5	0.74	ribosomal	macedocin	Streptococcus macedonicus
BGC0000547.5	0.71	ribosomal	salivaricin 9	Streptococcus salivarius
BGC0000548.4	0.65	ribosomal	salivaricin A	Streptococcus salivarius
BGC0000534.3	0.63	ribosomal	mutacin K8	Streptococcus mutans
BGC0000521.3	0.61	ribosomal	lacticin 481	Lactococcus lactis subsp. lactis
BGC0000499.3	0.60	ribosomal	butyrivibriocin OR79	Butyrivibrio fibrisolvens

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000550.3	1.00	ribosomal	salivaricin G32	Streptococcus salivarius
BGC0001788.3	0.84	ribosomal	suicin 65	Streptococcus suis
BGC0000557.5	0.79	ribosomal	streptococcin A-FF22	Streptococcus pyogenes
BGC0000562.3	0.75	ribosomal	variacin	Kocuria varians
BGC0000526.5	0.74	ribosomal	macedocin	Streptococcus macedonicus
BGC0000547.5	0.71	ribosomal	salivaricin 9	Streptococcus salivarius
BGC0000548.4	0.65	ribosomal	salivaricin A	Streptococcus salivarius
BGC0000534.3	0.63	ribosomal	mutacin K8	Streptococcus mutans
BGC0000521.3	0.61	ribosomal	lacticin 481	Lactococcus lactis subsp. lactis
BGC0000499.3	0.60	ribosomal	butyrivibriocin OR79	Butyrivibrio fibrisolvens

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for PNU26_RS06595

PNU26_RS06580

Leader:

MKKDVVIESIKEVSLEELDQIIGA

PNU26_RS06585

Leader:

MKKDAIIESIKEVSLEELDQIIGA

Shared core:

GNGVFKTISHECHLNTWAFLATCCS

Core with dehydrations:

GNGVFKDhbIDhaHECysHLNDhbWAFLADhbCysCysDha

antiSMASH-DB 4.0 matches for PNU26_RS06580

100.0%

NZ_CP018188.1and 17 others:

NZ_CP018188.1 Lanthipeptides: BSR19_RS11175_lanthipeptideNZ_CP066093.1 Lanthipeptides: I6I02_RS07300_lanthipeptideNZ_CP066093.1 Lanthipeptides: I6I02_RS07295_lanthipeptideNZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09705_lanthipeptideNZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09700_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09300_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09295_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09300_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09295_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06585_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06580_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06585_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06580_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS05120_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS05115_lanthipeptideNZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04335_lanthipeptideNZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04330_lanthipeptide

Lanthipeptides: BSR19_RS11180_lanthipeptide

1

GNGVFKTISHECHLNTWAFLATCCS

25

GNGVFKTISHECHLNTWAFLATCCS

1

GNGVFKTISHECHLNTWAFLATCCS

25

92.3%

NZ_ALSD01000046.1and 49 others:

NZ_CAAHGW010000010.1 Lanthipeptides: E9435_RS08890_lanthipeptideNZ_CAAHHE010000002.1 Lanthipeptides: E9499_RS02935_lanthipeptideNZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08685_lanthipeptideNZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08680_lanthipeptideNZ_CAAHHN010000003.1 Lanthipeptides: E9502_RS05700_lanthipeptideNZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08730_lanthipeptideNZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08725_lanthipeptideNZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08980_lanthipeptideNZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08975_lanthipeptideNZ_CAAHIB010000001.1 Lanthipeptides: E9539_RS01070_lanthipeptideNZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09265_lanthipeptideNZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09260_lanthipeptideNZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08765_lanthipeptideNZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08760_lanthipeptideNZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08915_lanthipeptideNZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08910_lanthipeptideNZ_CAAHKQ010000003.1 Lanthipeptides: E9664_RS02170_lanthipeptideNZ_CAAHKY010000014.1 Lanthipeptides: E9668_RS09655_lanthipeptideNZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03455_lanthipeptideNZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03450_lanthipeptideNZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08825_lanthipeptideNZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08820_lanthipeptideNZ_CAAHRY010000002.1 Lanthipeptides: E9986_RS03170_lanthipeptideNZ_CAAIES010000002.1 Lanthipeptides: FAH15_RS02470_lanthipeptideNZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08470_lanthipeptideNZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08465_lanthipeptideNZ_CAAIJM010000015.1 Lanthipeptides: FAI23_RS09580_lanthipeptideNZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09035_lanthipeptideNZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09030_lanthipeptideNZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08495_lanthipeptideNZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08490_lanthipeptideNZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08505_lanthipeptideNZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08500_lanthipeptideNZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06790_lanthipeptideNZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06785_lanthipeptideNZ_CM001076.1 Lanthipeptides: SDD27957_RS04310_lanthipeptideNZ_CM001076.1 Lanthipeptides: SDD27957_RS04305_lanthipeptideNZ_CP035426.1 Lanthipeptides: ETT73_RS02595_lanthipeptideNZ_CP035426.1 Lanthipeptides: ETT73_RS02590_lanthipeptideNZ_CP035428.1 Lanthipeptides: ETT71_RS02815_lanthipeptideNZ_CP035437.1 Lanthipeptides: ETT62_RS06680_lanthipeptideNZ_CP035437.1 Lanthipeptides: ETT62_RS06675_lanthipeptideNZ_CP035443.1 Lanthipeptides: ETT56_RS07265_lanthipeptideNZ_GL636070.1 Lanthipeptides: HMPREF9171_RS105315_lanthipeptideNZ_LR793258.1 Lanthipeptides: HV369_RS03145_lanthipeptideNZ_LR793258.1 Lanthipeptides: HV369_RS03140_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS06755_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS06750_lanthipeptideNZ_LT545678.1 Lanthipeptides: BJR96_RS07040_lanthipeptide

Lanthipeptides: SAG0161_RS120605_lanthipeptide

2

NGVFKTISHECHLNTWAFLATCCS

25

NGVFKTISHECHLNTWAFLATCCS

3

NGVFKTISHECHLNTWAFLATCCS

26

88.5%

NZ_CAAHKQ010000003.1:

Lanthipeptides: E9664_RS02165_lanthipeptide

2

NGVFKTISHECHLNTWAFLATCCS

25

NGVFKTISHECHLNTWAFLA CCS

3

NGVFKTISHECHLNTWAFLAICCS

26

with 60 more sequence matches

Only the first 10 are displayed here.

88.5%

NZ_CP060646.1:

Lanthipeptides: H7789_RS06845_lanthipeptide

2

NGVFKTISHECHLNTWAFLATCCS

25

NGVFKTISHECHLNTWA LATCCS

3

NGVFKTISHECHLNTWASLATCCS

26

80.0%

NZ_AP025017.1:

Lanthipeptides: MANAM107_RS05920_lanthipeptide

2

NGVFKTISHECHLNTWAFLATCCS

25

NGV TISHECHLNTWAF TCCS

1

NGVITTISHECHLNTWAFAFTCCS

24

76.9%

NC_012470.1and 11 others:

NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS06485_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05185_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05180_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09835_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09830_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05350_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05345_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05065_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05060_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05580_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05575_lanthipeptide

Lanthipeptides: SZO_RS04070_lanthipeptide

2

NGVFKTISHECHLNTWAFLATCCS

25

NGVFKTISHECH+N+W FL TCCS

3

NGVFKTISHECHMNSWQFLFTCCS

26

76.0%

NZ_CP023483.1:

Lanthipeptides: CNY62_RS11970_lanthipeptide

1

GNGVFKTISHECHLNTWAFLATCCS

25

GNG +TISHECH+NTW FL TCCS

1

GNGAIRTISHECHMNTWQFLFTCCS

25

76.0%

NZ_CP084014.1and 6 others:

NZ_CP084014.1 Lanthipeptides: LCQ72_RS00100_lanthipeptideNZ_CP084014.1 Lanthipeptides: LCQ72_RS00095_lanthipeptideNZ_CP094679.1 Lanthipeptides: K5I24_RS13105_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12415_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12410_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12405_lanthipeptide

Lanthipeptides: LCQ72_RS00105_lanthipeptide

1

GNGVFKTISHECHLNTWAFLATCC

24

GNGV KTISHEC++NTW FL TCC

1

GNGVLKTISHECNMNTWQFLFTCC

24

76.0%

NZ_FOZB01000002.1:

Lanthipeptides: BM306_RS07850_lanthipeptide

1

GNGVFKTISHECHLNTWAFLATCCS

25

G+GVF+TISHECH+NTW F+ TCCS

1

GDGVFRTISHECHMNTWMFIFTCCS

25

76.0%

NZ_LT732526.1and 1 other:

NZ_LT732526.1 Lanthipeptides: BQ9856_RS23075_lanthipeptide

Lanthipeptides: BQ9856_RS23080_lanthipeptide

1

GNGVFKTISHECHLNTWAFLATCCS

25

GNGV KTISHEC +NTW F+ TCCS

1

GNGVIKTISHECAMNTWQFIFTCCS

25

72.0%

NZ_GL985606.1:

Lanthipeptides: HMPREF9062_RS00700_lanthipeptide

1

GNGVFKTISHECHLNTWAFLATCC

24

GNGVF TISHEC+ N+WAF+ TCC

1

GNGVFHTISHECYYNSWAFIFTCC

24

72.0%

NZ_JAEEGA010000010.1:

Lanthipeptides: I6N95_RS15660_lanthipeptide

1

GNGVFKTISHECHLNTWAFLATCCS

25

GNGV KTISHECH+N+W ++ TCCS

1

GNGVIKTISHECHMNSWQWIFTCCS

25

72.0%

NZ_WBPF01000002.1:

Lanthipeptides: F8162_RS00195_lanthipeptide

1

GNGVFKTISHECHLNTWAFLATCCS

25

G F TISHECH NTW FL TCCS

1

DKGQFDTISHECHWNTWQFLFTCCS

25

MIBiG 4.0 matches for PNU26_RS06580

20.0%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

2

NGVFKTISHECHLN

15

NG + T++ EC N

15

NGGWCTLTKECQPN

28

12.8%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

7

TISHECHLN

15

T+S EC N

29

TLSKECQPN

37

PNU26_RS06590

Leader:

MKNNKIHLEALEALQELKMEEIDNLLGG

Core:

AGHGVNTISAECRWNSLQAIFTCC

Core with dehydrations:

AGHGVNDhbIDhaAECysRWNDhaLQAIFDhbCysCys

antiSMASH-DB 4.0 matches for PNU26_RS06590

100.0%

NC_012470.1and 15 others:

NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS10120_lanthipeptideNZ_CP018188.1 Lanthipeptides: BSR19_RS11185_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05190_lanthipeptideNZ_CP066093.1 Lanthipeptides: I6I02_RS07305_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09825_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05340_lanthipeptideNZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09695_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09305_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09305_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06590_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06590_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS10860_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05070_lanthipeptideNZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04325_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05570_lanthipeptide

Lanthipeptides: SZO_RS10260_lanthipeptide

1

AGHGVNTISAECRWNSLQAIFTCC

24

AGHGVNTISAECRWNSLQAIFTCC

1

AGHGVNTISAECRWNSLQAIFTCC

24

95.8%

NZ_ALSD01000046.1and 5 others:

NZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06795_lanthipeptideNZ_CM001076.1 Lanthipeptides: SDD27957_RS10995_lanthipeptideNZ_GL636070.1 Lanthipeptides: HMPREF9171_RS1000000113590_lanthipeptideNZ_LR793258.1 Lanthipeptides: HV369_RS03150_lanthipeptideNZ_LT545678.1 Lanthipeptides: BJR96_RS11590_lanthipeptide

Lanthipeptides: SAG0161_RS1000000124770_lanthipeptide

1

AGHGVNTISAECRWNSLQAIFTCC

24

AGHGVNTISAECRWNSLQAIF+CC

1

AGHGVNTISAECRWNSLQAIFSCC

24

95.8%

NZ_CAAHGW010000010.1and 12 others:

NZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08770_lanthipeptideNZ_CAAHKQ010000003.1 Lanthipeptides: E9664_RS02160_lanthipeptideNZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08815_lanthipeptideNZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08475_lanthipeptideNZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09025_lanthipeptideNZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08495_lanthipeptideNZ_CP035426.1 Lanthipeptides: ETT73_RS02600_lanthipeptideNZ_CP035437.1 Lanthipeptides: ETT62_RS06670_lanthipeptideNZ_CP035443.1 Lanthipeptides: ETT56_RS07260_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS06745_lanthipeptideNZ_NWMU01000024.1 Lanthipeptides: CO197_RS09155_lanthipeptideNZ_VMMF01000004.1 Lanthipeptides: HT717_RS01580_lanthipeptide

Lanthipeptides: E9435_RS08895_lanthipeptide

2

GHGVNTISAECRWNSLQAIFTCC

24

GHGVNTISAECRWNSLQAIFTCC

2

GHGVNTISAECRWNSLQAIFTCC

24

with 46 more sequence matches

Only the first 10 are displayed here.

95.8%

NZ_CAAHHE010000002.1and 13 others:

NZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08675_lanthipeptideNZ_CAAHHN010000003.1 Lanthipeptides: E9502_RS05705_lanthipeptideNZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08735_lanthipeptideNZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08985_lanthipeptideNZ_CAAHIB010000001.1 Lanthipeptides: E9539_RS01075_lanthipeptideNZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09255_lanthipeptideNZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08920_lanthipeptideNZ_CAAHKY010000014.1 Lanthipeptides: E9668_RS09650_lanthipeptideNZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03445_lanthipeptideNZ_CAAHRY010000002.1 Lanthipeptides: E9986_RS03175_lanthipeptideNZ_CAAIES010000002.1 Lanthipeptides: FAH15_RS02475_lanthipeptideNZ_CAAIJM010000015.1 Lanthipeptides: FAI23_RS09585_lanthipeptideNZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08485_lanthipeptide

Lanthipeptides: E9499_RS02930_lanthipeptide

1

AGHGVNTISAECRWNSLQAIFTCC

24

GHGVNTISAECRWNSLQAIFTCC

1

GGHGVNTISAECRWNSLQAIFTCC

24

70.8%

NC_013928.1and 4 others:

NZ_CP023477.1 Lanthipeptides: CO204_RS01890_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS01095_lanthipeptideNZ_CP061071.1 Lanthipeptides: IBL27_RS01750_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07560_lanthipeptide

Lanthipeptides: SMUNN2025_RS09965_lanthipeptide

1

AGHGVNTISAECRWNSLQAIFTCC

24

G NTIS++CRWNSLQAIF+CC

1

GGRASNTISSDCRWNSLQAIFSCC

24

64.0%

NZ_JAEEGA010000010.1:

Lanthipeptides: I6N95_RS15660_lanthipeptide

2

GHGV-NTISAECRWNSLQAIFTCC

24

G+GV TIS EC NS Q IFTCC

1

GNGVIKTISHECHMNSWQWIFTCC

24

62.5%

NZ_GL985606.1:

Lanthipeptides: HMPREF9062_RS00700_lanthipeptide

2

GHGV-NTISAECRWNSLQAIFTCC

24

G+GV +TIS EC +NS IFTCC

1

GNGVFHTISHECYYNSWAFIFTCC

24

62.5%

NZ_QTVL01000002.1and 5 others:

NZ_QTVL01000002.1 Lanthipeptides: DWZ44_RS04150_lanthipeptideNZ_QTZB01000015.1 Lanthipeptides: DXC15_RS14340_lanthipeptideNZ_QTZB01000015.1 Lanthipeptides: DXC15_RS14335_lanthipeptideNZ_QUKU01000003.1 Lanthipeptides: DXC27_RS02940_lanthipeptideNZ_QUKU01000003.1 Lanthipeptides: DXC27_RS02935_lanthipeptide

Lanthipeptides: DWZ44_RS04155_lanthipeptide

2

GHGV-NTISAECRWNSLQAIFTCC

24

G GV TIS EC N+ Q IFTCC

1

GDGVFRTISHECNMNTWQFIFTCC

24

60.0%

NZ_GL882519.1:

Lanthipeptides: HMPREF9056_RS03330_lanthipeptide

2

GHGVN-TISAECRWNSLQAIFTCC

24

G+GV T+S EC NS Q IFTCC

1

GNGVYYTLSHECHMNSWQFIFTCC

24

60.0%

NZ_LT732526.1and 1 other:

NZ_LT732526.1 Lanthipeptides: BQ9856_RS23075_lanthipeptide

Lanthipeptides: BQ9856_RS23080_lanthipeptide

2

GHGV-NTISAECRWNSLQAIFTCC

24

G+GV TIS EC N+ Q IFTCC

1

GNGVIKTISHECAMNTWQFIFTCC

24

58.3%

NZ_CP084014.1and 6 others:

NZ_CP084014.1 Lanthipeptides: LCQ72_RS00100_lanthipeptideNZ_CP084014.1 Lanthipeptides: LCQ72_RS00095_lanthipeptideNZ_CP094679.1 Lanthipeptides: K5I24_RS13105_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12415_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12410_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12405_lanthipeptide

Lanthipeptides: LCQ72_RS00105_lanthipeptide

2

GHGV-NTISAECRWNSLQAIFTCC

24

G+GV TIS EC N+ Q +FTCC

1

GNGVLKTISHECNMNTWQFLFTCC

24

58.3%

NZ_MSRJ01000005.1:

Lanthipeptides: BKH06_RS03755_lanthipeptide

5

VNTISAECRWNSLQAIFTCC

24

V TIS EC NS Q IFTCC

4

VTTISHECNMNSWQFIFTCC

23

56.0%

NZ_FOZB01000002.1:

Lanthipeptides: BM306_RS07850_lanthipeptide

2

GHGV-NTISAECRWNSLQAIFTCC

24

G GV TIS EC N+ IFTCC

1

GDGVFRTISHECHMNTWMFIFTCC

24

MIBiG 4.0 matches for PNU26_RS06590

12.8%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

7

TISAECRWN

15

T+S EC+ N

29

TLSKECQPN

37

11.8%

BGC0000535.4 (ADJ56352.1):

Lanthipeptide: nisin A

4

GVNTISAECR

13

G N +A C

18

GCNMKTATCH

27

PNU26_RS06620

Leader:

MIAMKNSKDVLNNAIEEVSEKELMEVAGG

Core:

KKGPGWIATITDDCPNSIFVCC

Core with dehydrations:

KKGPGWIADhbIDhbDDCysPNDhaIFVCysCys

antiSMASH-DB 4.0 matches for PNU26_RS06620

100.0%

NZ_JAQDVH010000019.1and 3 others:

NZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09335_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06620_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06620_lanthipeptide

Lanthipeptides: PGU04_RS09335_lanthipeptide

1

KKGPGWIATITDDCPNSIFVCC

22

KKGPGWIATITDDCPNSIFVCC

1

KKGPGWIATITDDCPNSIFVCC

22

95.5%

NZ_CP018188.1and 1 other:

NZ_VDNV01000006.1 Lanthipeptides: FSV44_RS08680_lanthipeptide

Lanthipeptides: BSR19_RS10820_lanthipeptide

1

KKGPGWIATITDDCPNSIFVCC

22

K+GPGWIATITDDCPNSIFVCC

1

KRGPGWIATITDDCPNSIFVCC

22

90.9%

NZ_PKIA01000004.1:

Lanthipeptides: CYK22_RS03780_lanthipeptide

1

KKGPGWIATITDDCPNSIFVCC

22

K+GPGWIATITDDCPNS+FVCC

1

KRGPGWIATITDDCPNSVFVCC

22

with 62 more sequence matches

Only the first 10 are displayed here.

86.4%

NC_004070.1and 26 others:

NC_008024.1 Lanthipeptides: MGAS10750_RS08460_lanthipeptideNZ_CAAHHZ010000002.1 Lanthipeptides: E9518_RS02835_lanthipeptideNZ_CAAHIH010000002.1 Lanthipeptides: E9602_RS03585_lanthipeptideNZ_CAAHIO010000002.1 Lanthipeptides: E9584_RS04360_lanthipeptideNZ_CAAHJE010000002.1 Lanthipeptides: E9605_RS03435_lanthipeptideNZ_CAAHJS010000002.1 Lanthipeptides: E9628_RS02300_lanthipeptideNZ_CAAHKC010000012.1 Lanthipeptides: E9636_RS08085_lanthipeptideNZ_CAAHMR010000003.1 Lanthipeptides: E9727_RS05510_lanthipeptideNZ_CAAHQE010000003.1 Lanthipeptides: E9931_RS04945_lanthipeptideNZ_CAAHQG010000004.1 Lanthipeptides: E9903_RS05690_lanthipeptideNZ_CAAIFD010000008.1 Lanthipeptides: FAG63_RS07845_lanthipeptideNZ_CAAJDK010000010.1 Lanthipeptides: FAO79_RS08000_lanthipeptideNZ_CAAJFI010000003.1 Lanthipeptides: FAP60_RS03740_lanthipeptideNZ_CP008926.1 Lanthipeptides: DP15_RS03855_lanthipeptideNZ_CP035434.1 Lanthipeptides: ETT65_RS08240_lanthipeptideNZ_CP035435.1 Lanthipeptides: ETT64_RS07905_lanthipeptideNZ_CP035447.1 Lanthipeptides: ETT52_RS07920_lanthipeptideNZ_CP035449.1 Lanthipeptides: ETT50_RS08255_lanthipeptideNZ_CP035453.1 Lanthipeptides: ETT46_RS08220_lanthipeptideNZ_CP060646.1 Lanthipeptides: H7789_RS07920_lanthipeptideNZ_CP065054.1 Lanthipeptides: I2432_RS09105_lanthipeptideNZ_LRGW01000003.1 Lanthipeptides: AWU01_RS03260_lanthipeptideNZ_LS483298.1 Lanthipeptides: DQM39_RS08650_lanthipeptideNZ_LS483407.1 Lanthipeptides: DQM86_RS08100_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS07865_lanthipeptideNZ_LS483430.1 Lanthipeptides: DQN28_RS07600_lanthipeptide

Lanthipeptides: SPYM3_RS08605_lanthipeptide

1

KKGPGWIATITDDCPNSIFVCC

22

KKG GW ATITDDCPNS+FVCC

1

KKGSGWFATITDDCPNSVFVCC

22

81.8%

NZ_CAAIJM010000014.1:

Lanthipeptides: FAI23_RS09465_lanthipeptide

1

KKGPGWIATITDDCPNSIFVCC

22

KK GW ATITDDCPNS+FVCC

1

KKVSGWFATITDDCPNSVFVCC

22

81.8%

NZ_CAJHJN010000010.1and 4 others:

NZ_CP066093.1 Lanthipeptides: I6I02_RS06995_lanthipeptideNZ_JACLQK010000029.1 Lanthipeptides: H7U04_RS10750_lanthipeptideNZ_JADPEB010000003.1 Lanthipeptides: I4U26_RS02855_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS05170_lanthipeptide

Lanthipeptides: JMZ68_RS08975_lanthipeptide

1

KKGPGWIATITDDCPNSIFVCC

22

K+G GW ATITDDCPNS+FVCC

1

KRGTGWFATITDDCPNSVFVCC

22

77.3%

NZ_MJEH01000022.1and 1 other:

NZ_MJEH01000022.1 Lanthipeptides: BFG57_RS18360_lanthipeptide

Lanthipeptides: BFG57_RS18365_lanthipeptide

3

GPGWIATITDDCPNSIFVCC

22

G GWI+TITDDCPNSI VCC

1

GDGWISTITDDCPNSIIVCC

20

77.3%

NZ_NIHT01000008.1and 1 other:

NZ_NIHT01000008.1 Lanthipeptides: CDL23_RS06740_lanthipeptide

Lanthipeptides: CDL23_RS06745_lanthipeptide

2

KGPGWIATITDDCPNSIFVCC

22

G GW+ TITDDCPNSIFVCC

2

NGSGWLPTITDDCPNSIFVCC

22

75.0%

NZ_MJEH01000022.1:

Lanthipeptides: BFG57_RS09480_lanthipeptide

1

KKGPGWIATITDDCPNSIFVCC

22

K G GWI+TITDDCPNSI VCC

3

KPGDGWISTITDDCPNSIIVCC

24

72.7%

NZ_CP048273.1and 3 others:

NZ_CP048273.1 Lanthipeptides: M654_RS18555_lanthipeptideNZ_LT745776.1 Lanthipeptides: B2C81_RS11280_lanthipeptideNZ_LT745776.1 Lanthipeptides: B2C81_RS11275_lanthipeptide

Lanthipeptides: M654_RS18560_lanthipeptide

2

KGPGWIATITDDCPNSIFVCC

22

G GW TITDDCPNS+FVCC

1

AGCGWACTITDDCPNSVFVCC

21

72.7%

NZ_CP048890.1and 3 others:

NZ_CP071478.1 Lanthipeptides: J0P05_RS32905_lanthipeptideNZ_LUCO01000008.1 Lanthipeptides: BMBG_RS24280_lanthipeptideNZ_NVLN01000014.1 Lanthipeptides: CON11_RS24965_lanthipeptide

Lanthipeptides: BMG_RS30865_lanthipeptide

2

KGPGWIATITDDCPNSIFVCC

22

G GW TITDDCPNS+FVCC

1

AGCGWSCTITDDCPNSVFVCC

21

69.6%

NZ_BMMB01000007.1and 1 other:

NZ_BMMB01000007.1 Lanthipeptides: IEX62_RS15675_lanthipeptide

Lanthipeptides: IEX62_RS15680_lanthipeptide

3

GPGWIATITDDCPNSIFVCC

22

G GWI T+TDDCPNSI VCC

4

GDGWITTLTDDCPNSIIVCC

23

68.2%

NZ_CP036073.1and 11 others:

NZ_CP036073.1 Lanthipeptides: EXW45_RS04930_lanthipeptideNZ_CP036073.1 Lanthipeptides: EXW45_RS04925_lanthipeptideNZ_CP036073.1 Lanthipeptides: EXW45_RS04920_lanthipeptideNZ_CP036073.1 Lanthipeptides: EXW45_RS04915_lanthipeptideNZ_CP036073.1 Lanthipeptides: EXW45_RS04910_lanthipeptideNZ_NUEG01000031.1 Lanthipeptides: CN905_RS18915_lanthipeptideNZ_NUEG01000031.1 Lanthipeptides: CN905_RS18910_lanthipeptideNZ_PVRT01000001.1 Lanthipeptides: C6359_RS05275_lanthipeptideNZ_PVRT01000001.1 Lanthipeptides: C6359_RS05270_lanthipeptideNZ_PVRT01000001.1 Lanthipeptides: C6359_RS05265_lanthipeptideNZ_PVRT01000001.1 Lanthipeptides: C6359_RS05260_lanthipeptide

Lanthipeptides: EXW45_RS04935_lanthipeptide

2

KGPGWIATITDDCPNSIFVCC

22

G GW+ T+TDDCPNS+FVCC

1

AGCGWLCTVTDDCPNSVFVCC

21

MIBiG 4.0 matches for PNU26_RS06620

17.4%

BGC0002111.3 (EVG22_32245):

Lanthipeptide: andalusicin A or andalusicin B

5

GWIATITDDC

14

W +TI+++C

14

AWASTISNNC

23

17.4%

BGC0002111.3 (multiple genes):

Lanthipeptide: andalusicin A or andalusicin B

6

WIATITDDC

14

W +TI+++C

15

WASTISNNC

23

13.3%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

5

GWIATITDDCPN

16

GW + PN

17

GWCTLTKECQPN

28

Lanthipeptide(s) for PNU26_RS06625

PNU26_RS06580

Leader:

MKKDVVIESIKEVSLEELDQIIGA

PNU26_RS06585

Leader:

MKKDAIIESIKEVSLEELDQIIGA

Shared core:

GNGVFKTISHECHLNTWAFLATCCS

Core with dehydrations:

GNGVFKDhbIDhaHECysHLNDhbWAFLADhbCysCysDha

antiSMASH-DB 4.0 matches for PNU26_RS06580

100.0%

NZ_CP018188.1and 17 others:

NZ_CP018188.1 Lanthipeptides: BSR19_RS11175_lanthipeptideNZ_CP066093.1 Lanthipeptides: I6I02_RS07300_lanthipeptideNZ_CP066093.1 Lanthipeptides: I6I02_RS07295_lanthipeptideNZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09705_lanthipeptideNZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09700_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09300_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09295_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09300_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09295_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06585_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06580_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06585_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06580_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS05120_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS05115_lanthipeptideNZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04335_lanthipeptideNZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04330_lanthipeptide

Lanthipeptides: BSR19_RS11180_lanthipeptide

1

GNGVFKTISHECHLNTWAFLATCCS

25

GNGVFKTISHECHLNTWAFLATCCS

1

GNGVFKTISHECHLNTWAFLATCCS

25

92.3%

NZ_ALSD01000046.1and 49 others:

NZ_CAAHGW010000010.1 Lanthipeptides: E9435_RS08890_lanthipeptideNZ_CAAHHE010000002.1 Lanthipeptides: E9499_RS02935_lanthipeptideNZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08685_lanthipeptideNZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08680_lanthipeptideNZ_CAAHHN010000003.1 Lanthipeptides: E9502_RS05700_lanthipeptideNZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08730_lanthipeptideNZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08725_lanthipeptideNZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08980_lanthipeptideNZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08975_lanthipeptideNZ_CAAHIB010000001.1 Lanthipeptides: E9539_RS01070_lanthipeptideNZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09265_lanthipeptideNZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09260_lanthipeptideNZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08765_lanthipeptideNZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08760_lanthipeptideNZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08915_lanthipeptideNZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08910_lanthipeptideNZ_CAAHKQ010000003.1 Lanthipeptides: E9664_RS02170_lanthipeptideNZ_CAAHKY010000014.1 Lanthipeptides: E9668_RS09655_lanthipeptideNZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03455_lanthipeptideNZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03450_lanthipeptideNZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08825_lanthipeptideNZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08820_lanthipeptideNZ_CAAHRY010000002.1 Lanthipeptides: E9986_RS03170_lanthipeptideNZ_CAAIES010000002.1 Lanthipeptides: FAH15_RS02470_lanthipeptideNZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08470_lanthipeptideNZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08465_lanthipeptideNZ_CAAIJM010000015.1 Lanthipeptides: FAI23_RS09580_lanthipeptideNZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09035_lanthipeptideNZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09030_lanthipeptideNZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08495_lanthipeptideNZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08490_lanthipeptideNZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08505_lanthipeptideNZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08500_lanthipeptideNZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06790_lanthipeptideNZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06785_lanthipeptideNZ_CM001076.1 Lanthipeptides: SDD27957_RS04310_lanthipeptideNZ_CM001076.1 Lanthipeptides: SDD27957_RS04305_lanthipeptideNZ_CP035426.1 Lanthipeptides: ETT73_RS02595_lanthipeptideNZ_CP035426.1 Lanthipeptides: ETT73_RS02590_lanthipeptideNZ_CP035428.1 Lanthipeptides: ETT71_RS02815_lanthipeptideNZ_CP035437.1 Lanthipeptides: ETT62_RS06680_lanthipeptideNZ_CP035437.1 Lanthipeptides: ETT62_RS06675_lanthipeptideNZ_CP035443.1 Lanthipeptides: ETT56_RS07265_lanthipeptideNZ_GL636070.1 Lanthipeptides: HMPREF9171_RS105315_lanthipeptideNZ_LR793258.1 Lanthipeptides: HV369_RS03145_lanthipeptideNZ_LR793258.1 Lanthipeptides: HV369_RS03140_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS06755_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS06750_lanthipeptideNZ_LT545678.1 Lanthipeptides: BJR96_RS07040_lanthipeptide

Lanthipeptides: SAG0161_RS120605_lanthipeptide

2

NGVFKTISHECHLNTWAFLATCCS

25

NGVFKTISHECHLNTWAFLATCCS

3

NGVFKTISHECHLNTWAFLATCCS

26

88.5%

NZ_CAAHKQ010000003.1:

Lanthipeptides: E9664_RS02165_lanthipeptide

2

NGVFKTISHECHLNTWAFLATCCS

25

NGVFKTISHECHLNTWAFLA CCS

3

NGVFKTISHECHLNTWAFLAICCS

26

with 60 more sequence matches

Only the first 10 are displayed here.

88.5%

NZ_CP060646.1:

Lanthipeptides: H7789_RS06845_lanthipeptide

2

NGVFKTISHECHLNTWAFLATCCS

25

NGVFKTISHECHLNTWA LATCCS

3

NGVFKTISHECHLNTWASLATCCS

26

80.0%

NZ_AP025017.1:

Lanthipeptides: MANAM107_RS05920_lanthipeptide

2

NGVFKTISHECHLNTWAFLATCCS

25

NGV TISHECHLNTWAF TCCS

1

NGVITTISHECHLNTWAFAFTCCS

24

76.9%

NC_012470.1and 11 others:

NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS06485_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05185_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05180_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09835_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09830_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05350_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05345_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05065_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05060_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05580_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05575_lanthipeptide

Lanthipeptides: SZO_RS04070_lanthipeptide

2

NGVFKTISHECHLNTWAFLATCCS

25

NGVFKTISHECH+N+W FL TCCS

3

NGVFKTISHECHMNSWQFLFTCCS

26

76.0%

NZ_CP023483.1:

Lanthipeptides: CNY62_RS11970_lanthipeptide

1

GNGVFKTISHECHLNTWAFLATCCS

25

GNG +TISHECH+NTW FL TCCS

1

GNGAIRTISHECHMNTWQFLFTCCS

25

76.0%

NZ_CP084014.1and 6 others:

NZ_CP084014.1 Lanthipeptides: LCQ72_RS00100_lanthipeptideNZ_CP084014.1 Lanthipeptides: LCQ72_RS00095_lanthipeptideNZ_CP094679.1 Lanthipeptides: K5I24_RS13105_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12415_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12410_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12405_lanthipeptide

Lanthipeptides: LCQ72_RS00105_lanthipeptide

1

GNGVFKTISHECHLNTWAFLATCC

24

GNGV KTISHEC++NTW FL TCC

1

GNGVLKTISHECNMNTWQFLFTCC

24

76.0%

NZ_FOZB01000002.1:

Lanthipeptides: BM306_RS07850_lanthipeptide

1

GNGVFKTISHECHLNTWAFLATCCS

25

G+GVF+TISHECH+NTW F+ TCCS

1

GDGVFRTISHECHMNTWMFIFTCCS

25

76.0%

NZ_LT732526.1and 1 other:

NZ_LT732526.1 Lanthipeptides: BQ9856_RS23075_lanthipeptide

Lanthipeptides: BQ9856_RS23080_lanthipeptide

1

GNGVFKTISHECHLNTWAFLATCCS

25

GNGV KTISHEC +NTW F+ TCCS

1

GNGVIKTISHECAMNTWQFIFTCCS

25

72.0%

NZ_GL985606.1:

Lanthipeptides: HMPREF9062_RS00700_lanthipeptide

1

GNGVFKTISHECHLNTWAFLATCC

24

GNGVF TISHEC+ N+WAF+ TCC

1

GNGVFHTISHECYYNSWAFIFTCC

24

72.0%

NZ_JAEEGA010000010.1:

Lanthipeptides: I6N95_RS15660_lanthipeptide

1

GNGVFKTISHECHLNTWAFLATCCS

25

GNGV KTISHECH+N+W ++ TCCS

1

GNGVIKTISHECHMNSWQWIFTCCS

25

72.0%

NZ_WBPF01000002.1:

Lanthipeptides: F8162_RS00195_lanthipeptide

1

GNGVFKTISHECHLNTWAFLATCCS

25

G F TISHECH NTW FL TCCS

1

DKGQFDTISHECHWNTWQFLFTCCS

25

MIBiG 4.0 matches for PNU26_RS06580

20.0%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

2

NGVFKTISHECHLN

15

NG + T++ EC N

15

NGGWCTLTKECQPN

28

12.8%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

7

TISHECHLN

15

T+S EC N

29

TLSKECQPN

37

PNU26_RS06590

Leader:

MKNNKIHLEALEALQELKMEEIDNLLGG

Core:

AGHGVNTISAECRWNSLQAIFTCC

Core with dehydrations:

AGHGVNDhbIDhaAECysRWNDhaLQAIFDhbCysCys

antiSMASH-DB 4.0 matches for PNU26_RS06590

100.0%

NC_012470.1and 15 others:

NZ_CABY01000005.1 Lanthipeptides: SZBHS5_RS10120_lanthipeptideNZ_CP018188.1 Lanthipeptides: BSR19_RS11185_lanthipeptideNZ_CP029398.1 Lanthipeptides: DF184_RS05190_lanthipeptideNZ_CP066093.1 Lanthipeptides: I6I02_RS07305_lanthipeptideNZ_CP078012.1 Lanthipeptides: KV238_RS09825_lanthipeptideNZ_JAFLMI010000009.1 Lanthipeptides: J0638_RS05340_lanthipeptideNZ_JALDUD010000010.1 Lanthipeptides: M1G10_RS09695_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09305_lanthipeptideNZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09305_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06590_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06590_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS10860_lanthipeptideNZ_LR738724.1 Lanthipeptides: GPW69_RS05070_lanthipeptideNZ_PKIA01000004.1 Lanthipeptides: CYK22_RS04325_lanthipeptideNZ_VZNS01000007.1 Lanthipeptides: F6P79_RS05570_lanthipeptide

Lanthipeptides: SZO_RS10260_lanthipeptide

1

AGHGVNTISAECRWNSLQAIFTCC

24

AGHGVNTISAECRWNSLQAIFTCC

1

AGHGVNTISAECRWNSLQAIFTCC

24

95.8%

NZ_ALSD01000046.1and 5 others:

NZ_CAJHJS010000009.1 Lanthipeptides: JMX87_RS06795_lanthipeptideNZ_CM001076.1 Lanthipeptides: SDD27957_RS10995_lanthipeptideNZ_GL636070.1 Lanthipeptides: HMPREF9171_RS1000000113590_lanthipeptideNZ_LR793258.1 Lanthipeptides: HV369_RS03150_lanthipeptideNZ_LT545678.1 Lanthipeptides: BJR96_RS11590_lanthipeptide

Lanthipeptides: SAG0161_RS1000000124770_lanthipeptide

1

AGHGVNTISAECRWNSLQAIFTCC

24

AGHGVNTISAECRWNSLQAIF+CC

1

AGHGVNTISAECRWNSLQAIFSCC

24

95.8%

NZ_CAAHGW010000010.1and 12 others:

NZ_CAAHKK010000019.1 Lanthipeptides: E9649_RS08770_lanthipeptideNZ_CAAHKQ010000003.1 Lanthipeptides: E9664_RS02160_lanthipeptideNZ_CAAHQE010000012.1 Lanthipeptides: E9931_RS08815_lanthipeptideNZ_CAAIIA010000012.1 Lanthipeptides: FAH55_RS08475_lanthipeptideNZ_CAAINV010000013.1 Lanthipeptides: FAI86_RS09025_lanthipeptideNZ_CAAJFI010000013.1 Lanthipeptides: FAP60_RS08495_lanthipeptideNZ_CP035426.1 Lanthipeptides: ETT73_RS02600_lanthipeptideNZ_CP035437.1 Lanthipeptides: ETT62_RS06670_lanthipeptideNZ_CP035443.1 Lanthipeptides: ETT56_RS07260_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS06745_lanthipeptideNZ_NWMU01000024.1 Lanthipeptides: CO197_RS09155_lanthipeptideNZ_VMMF01000004.1 Lanthipeptides: HT717_RS01580_lanthipeptide

Lanthipeptides: E9435_RS08895_lanthipeptide

2

GHGVNTISAECRWNSLQAIFTCC

24

GHGVNTISAECRWNSLQAIFTCC

2

GHGVNTISAECRWNSLQAIFTCC

24

with 46 more sequence matches

Only the first 10 are displayed here.

95.8%

NZ_CAAHHE010000002.1and 13 others:

NZ_CAAHHF010000009.1 Lanthipeptides: E9478_RS08675_lanthipeptideNZ_CAAHHN010000003.1 Lanthipeptides: E9502_RS05705_lanthipeptideNZ_CAAHHU010000009.1 Lanthipeptides: E9510_RS08735_lanthipeptideNZ_CAAHHW010000012.1 Lanthipeptides: E9525_RS08985_lanthipeptideNZ_CAAHIB010000001.1 Lanthipeptides: E9539_RS01075_lanthipeptideNZ_CAAHIV010000024.1 Lanthipeptides: E9612_RS09255_lanthipeptideNZ_CAAHKP010000014.1 Lanthipeptides: E9652_RS08920_lanthipeptideNZ_CAAHKY010000014.1 Lanthipeptides: E9668_RS09650_lanthipeptideNZ_CAAHLP010000002.1 Lanthipeptides: E9684_RS03445_lanthipeptideNZ_CAAHRY010000002.1 Lanthipeptides: E9986_RS03175_lanthipeptideNZ_CAAIES010000002.1 Lanthipeptides: FAH15_RS02475_lanthipeptideNZ_CAAIJM010000015.1 Lanthipeptides: FAI23_RS09585_lanthipeptideNZ_CAAIRS010000012.1 Lanthipeptides: FAK24_RS08485_lanthipeptide

Lanthipeptides: E9499_RS02930_lanthipeptide

1

AGHGVNTISAECRWNSLQAIFTCC

24

GHGVNTISAECRWNSLQAIFTCC

1

GGHGVNTISAECRWNSLQAIFTCC

24

70.8%

NC_013928.1and 4 others:

NZ_CP023477.1 Lanthipeptides: CO204_RS01890_lanthipeptideNZ_CP050270.1 Lanthipeptides: HB753_RS01095_lanthipeptideNZ_CP061071.1 Lanthipeptides: IBL27_RS01750_lanthipeptideNZ_JALDUN010000005.1 Lanthipeptides: M1F82_RS07560_lanthipeptide

Lanthipeptides: SMUNN2025_RS09965_lanthipeptide

1

AGHGVNTISAECRWNSLQAIFTCC

24

G NTIS++CRWNSLQAIF+CC

1

GGRASNTISSDCRWNSLQAIFSCC

24

64.0%

NZ_JAEEGA010000010.1:

Lanthipeptides: I6N95_RS15660_lanthipeptide

2

GHGV-NTISAECRWNSLQAIFTCC

24

G+GV TIS EC NS Q IFTCC

1

GNGVIKTISHECHMNSWQWIFTCC

24

62.5%

NZ_GL985606.1:

Lanthipeptides: HMPREF9062_RS00700_lanthipeptide

2

GHGV-NTISAECRWNSLQAIFTCC

24

G+GV +TIS EC +NS IFTCC

1

GNGVFHTISHECYYNSWAFIFTCC

24

62.5%

NZ_QTVL01000002.1and 5 others:

NZ_QTVL01000002.1 Lanthipeptides: DWZ44_RS04150_lanthipeptideNZ_QTZB01000015.1 Lanthipeptides: DXC15_RS14340_lanthipeptideNZ_QTZB01000015.1 Lanthipeptides: DXC15_RS14335_lanthipeptideNZ_QUKU01000003.1 Lanthipeptides: DXC27_RS02940_lanthipeptideNZ_QUKU01000003.1 Lanthipeptides: DXC27_RS02935_lanthipeptide

Lanthipeptides: DWZ44_RS04155_lanthipeptide

2

GHGV-NTISAECRWNSLQAIFTCC

24

G GV TIS EC N+ Q IFTCC

1

GDGVFRTISHECNMNTWQFIFTCC

24

60.0%

NZ_GL882519.1:

Lanthipeptides: HMPREF9056_RS03330_lanthipeptide

2

GHGVN-TISAECRWNSLQAIFTCC

24

G+GV T+S EC NS Q IFTCC

1

GNGVYYTLSHECHMNSWQFIFTCC

24

60.0%

NZ_LT732526.1and 1 other:

NZ_LT732526.1 Lanthipeptides: BQ9856_RS23075_lanthipeptide

Lanthipeptides: BQ9856_RS23080_lanthipeptide

2

GHGV-NTISAECRWNSLQAIFTCC

24

G+GV TIS EC N+ Q IFTCC

1

GNGVIKTISHECAMNTWQFIFTCC

24

58.3%

NZ_CP084014.1and 6 others:

NZ_CP084014.1 Lanthipeptides: LCQ72_RS00100_lanthipeptideNZ_CP084014.1 Lanthipeptides: LCQ72_RS00095_lanthipeptideNZ_CP094679.1 Lanthipeptides: K5I24_RS13105_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12415_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12410_lanthipeptideNZ_JAQEYW010000015.1 Lanthipeptides: PG422_RS12405_lanthipeptide

Lanthipeptides: LCQ72_RS00105_lanthipeptide

2

GHGV-NTISAECRWNSLQAIFTCC

24

G+GV TIS EC N+ Q +FTCC

1

GNGVLKTISHECNMNTWQFLFTCC

24

58.3%

NZ_MSRJ01000005.1:

Lanthipeptides: BKH06_RS03755_lanthipeptide

5

VNTISAECRWNSLQAIFTCC

24

V TIS EC NS Q IFTCC

4

VTTISHECNMNSWQFIFTCC

23

56.0%

NZ_FOZB01000002.1:

Lanthipeptides: BM306_RS07850_lanthipeptide

2

GHGV-NTISAECRWNSLQAIFTCC

24

G GV TIS EC N+ IFTCC

1

GDGVFRTISHECHMNTWMFIFTCC

24

MIBiG 4.0 matches for PNU26_RS06590

12.8%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

7

TISAECRWN

15

T+S EC+ N

29

TLSKECQPN

37

11.8%

BGC0000535.4 (ADJ56352.1):

Lanthipeptide: nisin A

4

GVNTISAECR

13

G N +A C

18

GCNMKTATCH

27

PNU26_RS06620

Leader:

MIAMKNSKDVLNNAIEEVSEKELMEVAGG

Core:

KKGPGWIATITDDCPNSIFVCC

Core with dehydrations:

KKGPGWIADhbIDhbDDCysPNDhaIFVCysCys

antiSMASH-DB 4.0 matches for PNU26_RS06620

100.0%

NZ_JAQDVH010000019.1and 3 others:

NZ_JAQDVH010000019.1 Lanthipeptides: PGU04_RS09335_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06620_lanthipeptideNZ_JAQMJT010000006.1 Lanthipeptides: PNU26_RS06620_lanthipeptide

Lanthipeptides: PGU04_RS09335_lanthipeptide

1

KKGPGWIATITDDCPNSIFVCC

22

KKGPGWIATITDDCPNSIFVCC

1

KKGPGWIATITDDCPNSIFVCC

22

95.5%

NZ_CP018188.1and 1 other:

NZ_VDNV01000006.1 Lanthipeptides: FSV44_RS08680_lanthipeptide

Lanthipeptides: BSR19_RS10820_lanthipeptide

1

KKGPGWIATITDDCPNSIFVCC

22

K+GPGWIATITDDCPNSIFVCC

1

KRGPGWIATITDDCPNSIFVCC

22

90.9%

NZ_PKIA01000004.1:

Lanthipeptides: CYK22_RS03780_lanthipeptide

1

KKGPGWIATITDDCPNSIFVCC

22

K+GPGWIATITDDCPNS+FVCC

1

KRGPGWIATITDDCPNSVFVCC

22

with 62 more sequence matches

Only the first 10 are displayed here.

86.4%

NC_004070.1and 26 others:

NC_008024.1 Lanthipeptides: MGAS10750_RS08460_lanthipeptideNZ_CAAHHZ010000002.1 Lanthipeptides: E9518_RS02835_lanthipeptideNZ_CAAHIH010000002.1 Lanthipeptides: E9602_RS03585_lanthipeptideNZ_CAAHIO010000002.1 Lanthipeptides: E9584_RS04360_lanthipeptideNZ_CAAHJE010000002.1 Lanthipeptides: E9605_RS03435_lanthipeptideNZ_CAAHJS010000002.1 Lanthipeptides: E9628_RS02300_lanthipeptideNZ_CAAHKC010000012.1 Lanthipeptides: E9636_RS08085_lanthipeptideNZ_CAAHMR010000003.1 Lanthipeptides: E9727_RS05510_lanthipeptideNZ_CAAHQE010000003.1 Lanthipeptides: E9931_RS04945_lanthipeptideNZ_CAAHQG010000004.1 Lanthipeptides: E9903_RS05690_lanthipeptideNZ_CAAIFD010000008.1 Lanthipeptides: FAG63_RS07845_lanthipeptideNZ_CAAJDK010000010.1 Lanthipeptides: FAO79_RS08000_lanthipeptideNZ_CAAJFI010000003.1 Lanthipeptides: FAP60_RS03740_lanthipeptideNZ_CP008926.1 Lanthipeptides: DP15_RS03855_lanthipeptideNZ_CP035434.1 Lanthipeptides: ETT65_RS08240_lanthipeptideNZ_CP035435.1 Lanthipeptides: ETT64_RS07905_lanthipeptideNZ_CP035447.1 Lanthipeptides: ETT52_RS07920_lanthipeptideNZ_CP035449.1 Lanthipeptides: ETT50_RS08255_lanthipeptideNZ_CP035453.1 Lanthipeptides: ETT46_RS08220_lanthipeptideNZ_CP060646.1 Lanthipeptides: H7789_RS07920_lanthipeptideNZ_CP065054.1 Lanthipeptides: I2432_RS09105_lanthipeptideNZ_LRGW01000003.1 Lanthipeptides: AWU01_RS03260_lanthipeptideNZ_LS483298.1 Lanthipeptides: DQM39_RS08650_lanthipeptideNZ_LS483407.1 Lanthipeptides: DQM86_RS08100_lanthipeptideNZ_LS483425.1 Lanthipeptides: DQN36_RS07865_lanthipeptideNZ_LS483430.1 Lanthipeptides: DQN28_RS07600_lanthipeptide

Lanthipeptides: SPYM3_RS08605_lanthipeptide

1

KKGPGWIATITDDCPNSIFVCC

22

KKG GW ATITDDCPNS+FVCC

1

KKGSGWFATITDDCPNSVFVCC

22

81.8%

NZ_CAAIJM010000014.1:

Lanthipeptides: FAI23_RS09465_lanthipeptide

1

KKGPGWIATITDDCPNSIFVCC

22

KK GW ATITDDCPNS+FVCC

1

KKVSGWFATITDDCPNSVFVCC

22

81.8%

NZ_CAJHJN010000010.1and 4 others:

NZ_CP066093.1 Lanthipeptides: I6I02_RS06995_lanthipeptideNZ_JACLQK010000029.1 Lanthipeptides: H7U04_RS10750_lanthipeptideNZ_JADPEB010000003.1 Lanthipeptides: I4U26_RS02855_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS05170_lanthipeptide

Lanthipeptides: JMZ68_RS08975_lanthipeptide

1

KKGPGWIATITDDCPNSIFVCC

22

K+G GW ATITDDCPNS+FVCC

1

KRGTGWFATITDDCPNSVFVCC

22

77.3%

NZ_MJEH01000022.1and 1 other:

NZ_MJEH01000022.1 Lanthipeptides: BFG57_RS18360_lanthipeptide

Lanthipeptides: BFG57_RS18365_lanthipeptide

3

GPGWIATITDDCPNSIFVCC

22

G GWI+TITDDCPNSI VCC

1

GDGWISTITDDCPNSIIVCC

20

77.3%

NZ_NIHT01000008.1and 1 other:

NZ_NIHT01000008.1 Lanthipeptides: CDL23_RS06740_lanthipeptide

Lanthipeptides: CDL23_RS06745_lanthipeptide

2

KGPGWIATITDDCPNSIFVCC

22

G GW+ TITDDCPNSIFVCC

2

NGSGWLPTITDDCPNSIFVCC

22

75.0%

NZ_MJEH01000022.1:

Lanthipeptides: BFG57_RS09480_lanthipeptide

1

KKGPGWIATITDDCPNSIFVCC

22

K G GWI+TITDDCPNSI VCC

3

KPGDGWISTITDDCPNSIIVCC

24

72.7%

NZ_CP048273.1and 3 others:

NZ_CP048273.1 Lanthipeptides: M654_RS18555_lanthipeptideNZ_LT745776.1 Lanthipeptides: B2C81_RS11280_lanthipeptideNZ_LT745776.1 Lanthipeptides: B2C81_RS11275_lanthipeptide

Lanthipeptides: M654_RS18560_lanthipeptide

2

KGPGWIATITDDCPNSIFVCC

22

G GW TITDDCPNS+FVCC

1

AGCGWACTITDDCPNSVFVCC

21

72.7%

NZ_CP048890.1and 3 others:

NZ_CP071478.1 Lanthipeptides: J0P05_RS32905_lanthipeptideNZ_LUCO01000008.1 Lanthipeptides: BMBG_RS24280_lanthipeptideNZ_NVLN01000014.1 Lanthipeptides: CON11_RS24965_lanthipeptide

Lanthipeptides: BMG_RS30865_lanthipeptide

2

KGPGWIATITDDCPNSIFVCC

22

G GW TITDDCPNS+FVCC

1

AGCGWSCTITDDCPNSVFVCC

21

69.6%

NZ_BMMB01000007.1and 1 other:

NZ_BMMB01000007.1 Lanthipeptides: IEX62_RS15675_lanthipeptide

Lanthipeptides: IEX62_RS15680_lanthipeptide

3

GPGWIATITDDCPNSIFVCC

22

G GWI T+TDDCPNSI VCC

4

GDGWITTLTDDCPNSIIVCC

23

68.2%

NZ_CP036073.1and 11 others:

NZ_CP036073.1 Lanthipeptides: EXW45_RS04930_lanthipeptideNZ_CP036073.1 Lanthipeptides: EXW45_RS04925_lanthipeptideNZ_CP036073.1 Lanthipeptides: EXW45_RS04920_lanthipeptideNZ_CP036073.1 Lanthipeptides: EXW45_RS04915_lanthipeptideNZ_CP036073.1 Lanthipeptides: EXW45_RS04910_lanthipeptideNZ_NUEG01000031.1 Lanthipeptides: CN905_RS18915_lanthipeptideNZ_NUEG01000031.1 Lanthipeptides: CN905_RS18910_lanthipeptideNZ_PVRT01000001.1 Lanthipeptides: C6359_RS05275_lanthipeptideNZ_PVRT01000001.1 Lanthipeptides: C6359_RS05270_lanthipeptideNZ_PVRT01000001.1 Lanthipeptides: C6359_RS05265_lanthipeptideNZ_PVRT01000001.1 Lanthipeptides: C6359_RS05260_lanthipeptide

Lanthipeptides: EXW45_RS04935_lanthipeptide

2

KGPGWIATITDDCPNSIFVCC

22

G GW+ T+TDDCPNS+FVCC

1

AGCGWLCTVTDDCPNSVFVCC

21

MIBiG 4.0 matches for PNU26_RS06620

17.4%

BGC0002111.3 (EVG22_32245):

Lanthipeptide: andalusicin A or andalusicin B

5

GWIATITDDC

14

W +TI+++C

14

AWASTISNNC

23

17.4%

BGC0002111.3 (multiple genes):

Lanthipeptide: andalusicin A or andalusicin B

6

WIATITDDC

14

W +TI+++C

15

WASTISNNC

23

13.3%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

5

GWIATITDDCPN

16

GW + PN

17

GWCTLTKECQPN

28

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

No hits above weak threshold.

Weak hits (1):

NuR

Description: Nickel-responsive regulator
Species: Streptomyces coelicolor
Score: 23.28 out of 30.98

Confidence: weak

Lanthipeptides

TFBS Finder

Core peptide predictions

PNU26_RS06580 - Class II

Cleavage pHMM score: 5.20

RODEO score: 0

Monoisotopic mass: 2648.2 Da

Molecular weight: 2650.0 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2668.0 Da N = 1; 2686.0 Da N = 2

PNU26_RS06585 - Class II

Cleavage pHMM score: 5.20

RODEO score: 0

Monoisotopic mass: 2648.2 Da

Molecular weight: 2650.0 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2668.0 Da N = 1; 2686.0 Da N = 2

PNU26_RS06590 - Class II

Cleavage pHMM score: 0.10

RODEO score: 0

Monoisotopic mass: 2508.2 Da

Molecular weight: 2509.8 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2527.8 Da N = 1

PNU26_RS06620 - Class II

Cleavage pHMM score: 4.40

RODEO score: 0

Monoisotopic mass: 2313.1 Da

Molecular weight: 2314.7 Da

Number of bridges: 3

PNU26_RS06580 - Class II

Cleavage pHMM score: 5.20

RODEO score: 0

Monoisotopic mass: 2648.2 Da

Molecular weight: 2650.0 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2668.0 Da N = 1; 2686.0 Da N = 2

PNU26_RS06585 - Class II

Cleavage pHMM score: 5.20

RODEO score: 0

Monoisotopic mass: 2648.2 Da

Molecular weight: 2650.0 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2668.0 Da N = 1; 2686.0 Da N = 2

PNU26_RS06590 - Class II

Cleavage pHMM score: 0.10

RODEO score: 0

Monoisotopic mass: 2508.2 Da

Molecular weight: 2509.8 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2527.8 Da N = 1

PNU26_RS06620 - Class II

Cleavage pHMM score: 4.40

RODEO score: 0

Monoisotopic mass: 2313.1 Da

Molecular weight: 2314.7 Da

Number of bridges: 3

TFBS definitions

Regulator	Description

NZ_JAQMJT010000006.1 - Region 3 - phosphonate

Download region GenBank file

Download region SVG

Location: 56,920 - 73,288 nt. (total: 16,369 nt) Show pHMM detection rules used

phosphonate: (phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase or phosphonatesMeIsocitrateLyase))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: oxidase

PNU26_RS06740: pyruvate oxidase/decarboxylase

smcogs: SMCOG1055: pyruvate oxidase/decarboxylase

Transferases: aminotransferase transketolase

PNU26_RS06705: transketolase

smcogs: SMCOG1204: transketolase

PNU26_RS06715: aminotransferase class-III

smcogs: SMCOG1013: aminotransferase class-III

Ligases: synthase

PNU26_RS06710: 1-deoxy-D-xylulose-5-phosphate synthase

smcogs: SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase

PNU26_RS06725: 2-isopropylmalate synthase

smcogs: SMCOG1271: 2-isopropylmalate synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002670.2	0.47	other (other)	fosfonochlorin	Fusarium oxysporum f. sp. lycopersici 4287
BGC0000859.3	0.46	other (other)	ectoine	Methylomicrobium alcaliphilum
BGC0000855.3	0.46	other (other)	ectoine	Methylomicrobium kenyense
BGC0000938.5	0.46	other (aminocoumarin)	fosfomycin	Streptomyces fradiae
BGC0001510.5	0.43	other (other)	anisomycin	Streptomyces hygrospinosus
BGC0000857.3	0.42	other (other)	ectoine	Methylophaga alcalica
BGC0002700.2	0.41	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0000616.4	0.41	ribosomal	amylocyclicin	Bacillus velezensis FZB42
BGC0000854.3	0.41	other (other)	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000599.5	0.40	ribosomal	thuricin CD α, thuricin CD β	Bacillus thuringiensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002670.2	0.47	other (other)	fosfonochlorin	Fusarium oxysporum f. sp. lycopersici 4287
BGC0000859.3	0.46	other (other)	ectoine	Methylomicrobium alcaliphilum
BGC0000855.3	0.46	other (other)	ectoine	Methylomicrobium kenyense
BGC0000938.5	0.46	other (aminocoumarin)	fosfomycin	Streptomyces fradiae
BGC0001510.5	0.43	other (other)	anisomycin	Streptomyces hygrospinosus
BGC0000857.3	0.42	other (other)	ectoine	Methylophaga alcalica
BGC0002700.2	0.41	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0000616.4	0.41	ribosomal	amylocyclicin	Bacillus velezensis FZB42
BGC0000854.3	0.41	other (other)	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000599.5	0.40	ribosomal	thuricin CD α, thuricin CD β	Bacillus thuringiensis

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

NrtR

Description: NAD synthesis repressor
Species: Streptomyces coelicolor
Score: 27.92 out of 35.63

Confidence: medium

Additional weak hits (1):

GnfM

Description: Regulator of nitrogen-fixation genes
Species: Geobacter sulfurreducens PCA
Score: 20.57 out of 27.55

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
NrtR	NAD synthesis repressor