LOCUS       NZ_CP116257            23825 bp    DNA     linear   CON 15-DEC-2024
DEFINITION  Streptomyces lienomycini strain DSM 41475 chromosome, complete
            genome.
ACCESSION   NZ_CP116257
VERSION     NZ_CP116257.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces lienomycini
  ORGANISM  Streptomyces lienomycini
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7863969)
  AUTHORS   Ding,W.
  TITLE     Streptomyces riduolalong sp. nov., isolated from the soil of Tibet
            exhibits against Gram-positive bacteria activity
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7863969)
  AUTHORS   Ding,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JAN-2023) School of life sciences and biotechnology,
            Shanghai Jiaotong University, 800 Dongchuan, Shanghai, Shanghai
            200240, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: GS De Novo Assembler v. August-2022
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_027947595.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 16:03:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,183
            CDSs (total)                      :: 7,093
            Genes (coding)                    :: 6,850
            CDSs (with protein)               :: 6,850
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 243
            CDSs (without protein)            :: 243
            Pseudo Genes (ambiguous residues) :: 0 of 243
            Pseudo Genes (frameshifted)       :: 141 of 243
            Pseudo Genes (incomplete)         :: 121 of 243
            Pseudo Genes (internal stop)      :: 14 of 243
            Pseudo Genes (multiple problems)  :: 26 of 243
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:34:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4531040
            Orig. end                         :: >4554865
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP116257.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..>23825
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="23"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..>23825
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..>23825
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:>13825]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..>13825
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            699..2780
                     /locus_tag="BJ961_RS20520"
     CDS             699..2780
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031636.1"
                     /locus_tag="BJ961_RS20520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="iron ABC transporter permease"
                     /protein_id="WP_271414249.1"
                     /transl_table=11
                     /translation="MAVTATEPTTDPAARPPAAPTSRSGAAAVTAGIVLLVAVLAVVDI
                     TQGTAAVGPSEVLKALTGQAAADDASVVVASRLPRMTAGLLVGAVLGAAGAVLQAVSRN
                     VLASPDTLAVNAGSYLALGLVGATGVSLPMIASSGVAFAGGLAAAAVVLGLSGLGTGTV
                     RLVLAGTALMLGLNSMTQALLLLFPEQTKGLYEWNQGSIAQNGFDGVLQMLPIALAGLA
                     GLMLTARRVDALALGDDTARGVGVPVRATRVTVVVLAALLSAAAVTLAGPIGFVGLCAP
                     ALVRPLARRFRGLTRSRTAVPAAALTGAALVLGSDVLLRALIADPRAVSVPTGVVTSLV
                     GAVFLVAMALRVRDTAGAGAPDRLRTPGRGVFLATLTALAVVLVGLVIAAVLVGDSKLL
                     LGDVVNWAQGQAGRTVSFVLDTRVPRVLAALSAGAALALAGTLVQAVTRNPLAEPNVLG
                     VTGGGALGAVILVTTVPAAGTWGVAGAAFAGSAVTAVVVFGLAARGGFRQNRLVLVGIG
                     VASGTAALISLLIVLTDPFNANKALTWLSGSTYGRTMPDVVPVALALVVGIGVAVARRT
                     ELDLLSLDEDTPRLLGLRPARGRLGFLVLSVVLSSTAVACAGTIGFVGLVAPHAARALV
                     GRRHVRVVPVAVLLGATLVCAADLLGRTVIAPAQLGAGLMTAVIGTPYFLYLLVRSRR"
     gene            2840..3436
                     /locus_tag="BJ961_RS20525"
     CDS             2840..3436
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031635.1"
                     /locus_tag="BJ961_RS20525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3'-5' exonuclease"
                     /protein_id="WP_271414250.1"
                     /transl_table=11
                     /translation="MDRRGADGGHAGLLNVIDLEATCWDGQPPPGAVSEIIEIGLAVVD
                     LDARERVARHRILVRPVRSRVGAFCTELTGITQAEADRGVSLARACDTLTREHGAGARP
                     WASWGDYDREQLVRQCAADGVPFPFGRPAERAHTNAKAVFTEAHGLRRRPGMARALEIA
                     GLPLEGRHHRGVDDAWNIAALVLRLAAQDAWPGSC"
     misc_feature    complement(3447..3461)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.52"
                     /tool="antismash"
     misc_feature    3447..3464
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.07"
                     /tool="antismash"
     gene            3594..4931
                     /locus_tag="BJ961_RS20530"
     CDS             3594..4931
                     /GO_function="GO:0004806 - triacylglycerol lipase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971746.1"
                     /locus_tag="BJ961_RS20530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lipase family protein"
                     /protein_id="WP_271414251.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.4e-06, bitscore:
                     27.8, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.7e-06, bitscore:
                     26.3, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPRPRMLAAAIAAALALGAQAVPAVAADGPAGDSTTTTSRGVEI
                     PAFYTPPSELPGADGALVRSEPLPLALSLPGVDGPLPGRATRLMYKSTDANGEAVAVTG
                     AYIEPAAKWRGEGPRPLVAVAPGTMGQGDQCAASMALEHPLQLNGQTVSVGYEDLSVYR
                     LLLRGVAVVVTDYVGLGTTDRLHTYVNRVDGAHAVLDAVRAARSLDSASVTAESRVGLF
                     GYSQGGGATAAAAELQPSYAPDVELAGTYAGAPPADLTKVTEAIDGSDLAGALGWSLNG
                     FLQTEPALRPIADRYVNEAGREALKDLSTMCVGDALFGYGGDSSTDWTKTGQSLGDIIR
                     AEPALQDFLAEQRIGALKPAGPVRVATGTSDDLVPHGQARRLAVDWCDKGAKVTYVPVL
                     LPGVGSGLLNHFAPLLTDQGNAISWLTDRLEGEAAGSNCWSMPVQP"
     misc_feature    5015..5035
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.49"
                     /tool="antismash"
     gene            5113..6600
                     /gene="proP"
                     /locus_tag="BJ961_RS20535"
     CDS             5113..6600
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="proP"
                     /gene_functions="transport (smcogs) SMCOG1074: major
                     facilitator family transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446557.1"
                     /locus_tag="BJ961_RS20535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycine betaine/L-proline transporter ProP"
                     /protein_id="WP_271417113.1"
                     /transl_table=11
                     /translation="MPSSVAHLPRQVREELARRLRRTKRAFREEDVQVVEKPLLKRAVG
                     ASALGNCMEWFDFGVYSYLAATIGKVFFPGASPAAQVISSFATFAAAFVVRPLGGLFFG
                     PLGDRVGRQKVLATTMIMMALGTFSIGLIPSYATIGVAAPILLLLARMVQGFSTGGEYG
                     GATTFVAEYSPDRRRGFLSSWLDFGTFVGYALGSALVTVLNLSLTDAQMLHWGWRLPFL
                     IAGPLGIIGLYMRLKLEESPAFQQQLDEHEKGLAQESAGSEFKTIVREHWRPLLVCMGL
                     VLLYNVTNYMVTGYLPTYQTETLDRSSGFADVLVLIGMVWIVLLITFLGRLSDHVGRRP
                     LYAVGAAAMIVLAIPAFLLLRADGVWVPVLGVLLLSTLLACFAAPSAATLPALFPTAVR
                     YAAMAIGFNFAVAAFGGTTPLVAEALVSISGDELMPAYYLMVAGAIGLVTVRFLPESAQ
                     VPLHGSQPMVGSRQEQRELITTSKDLYSFSKDRSKAS"
     gene            complement(6564..7505)
                     /locus_tag="BJ961_RS20540"
     CDS             complement(6564..7505)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031632.1"
                     /locus_tag="BJ961_RS20540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DMT family transporter"
                     /protein_id="WP_271414252.1"
                     /transl_table=11
                     /translation="MNATTTRGTLLAALACVLVGGSFTANSLLGDYPYAGGQFLRYGLA
                     FLLLVPLAGPGATARLRALGTGRWLRLALLAAVGMVGFNLAVLAAERTAEPAVPGVFVG
                     CAPVVVAVLVPLLEGRGPQRIVLYGALFVAVGAFTVQGWGRTDGVGIAFSVCALAGEVG
                     FAVLAVPVLRPLGPRLLSTVVCGVAAAESAVVGVLADGAGWLRRPDAVEAGALLWQAVV
                     VTVVGFVCWYMGMQRIGAERATLFSGLIPVAAACTAPLVGTGSYGAAQAVGSALVFAGV
                     AVGSGVSLPFTRGRRRPAAGRQEAFERSLEKL"
     misc_feature    7600..7615
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.87"
                     /tool="antismash"
     misc_feature    7686..7699
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.8"
                     /tool="antismash"
     gene            7748..8470
                     /locus_tag="BJ961_RS20545"
     CDS             7748..8470
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971749.1"
                     /locus_tag="BJ961_RS20545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_271414253.1"
                     /transl_table=11
                     /translation="MATASVCVALLAGCGGDSGDEGEAFEGQSADDIAAKAVEATRQAK
                     SMHVKGDTRLEDGSTVTIDVSVDQEKNCEGTIGAGGTEADVRHTDATLYLRGDERYWRT
                     ALKQQPDAARKMVPELRDKWVKMPANDATTAGVCDKQGFVAAMDEDESERRGMKRGSTT
                     DVNGAKALELTKDASGGEKLTLYVATEGEPYLLKTTTEGGKNPGSVTFGEYGETVDPEQ
                     PPAAETVDMKDLAGGQRA"
     gene            complement(8490..8966)
                     /locus_tag="BJ961_RS20550"
     CDS             complement(8490..8966)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971750.1"
                     /locus_tag="BJ961_RS20550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MSMEG_6728 family protein"
                     /protein_id="WP_271414254.1"
                     /transl_table=11
                     /translation="MQTFLPHPGFRESALALDRRRLGKQRVEALQVLRGLTVPGYGWRR
                     HPAVRMWTGYEEALVRYGLDVCRVWREQGHQDSCAASLVAGLAESRPGEPVRDQPELAA
                     AGELPPWLGDEAFHRSHRSALVRKEPEVYAELFPGVPDDLPYVWPSSDRERGDA"
     gene            complement(8983..9966)
                     /locus_tag="BJ961_RS20555"
     CDS             complement(8983..9966)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525633.1"
                     /locus_tag="BJ961_RS20555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5914 domain-containing protein"
                     /protein_id="WP_271417114.1"
                     /transl_table=11
                     /translation="MRLRRRAVPWERQRPTWREARPAVIAAALKRAEARPSGNWYVLGA
                     STDVRPTRPLSGTVEGVEVVVWRDARGRLVGGPGACPHLGAPLADSPVRCGTLVCHWHG
                     LALDGAPFAGWEPLPVHDDGVLVWARLDTVGEEPPTPAPLVPDRPPRATALTSVWRGAG
                     TCEPEDVVANRLDPWHGAWFHPYSFVDLTVVGTPGETPHDDGNGDRFVVDVSFRLTGRL
                     VVPVRAEFTAPGPRTVVMRITEGEGAGSVVESHATPLGPDASGRPRTAVVEAVLATSDR
                     PGFPLARRLAPALRLLMRAAAGRLWRDDLAYAERRGHLRARGRFPG"
     gene            complement(10001..10996)
                     /locus_tag="BJ961_RS20560"
     CDS             complement(10001..10996)
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512784.1"
                     /locus_tag="BJ961_RS20560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_271414255.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.8e-116,
                     bitscore: 386.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.8e-64,
                     bitscore: 216.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGRELDAAGITDPALRAAYTRCRLLNARHGRTYFLATRLLPADR
                     RPAVHALYGFARWADDIVDDTAADATPAERAAALTRLDRLLRRSLTGGGPTDEPVVLAL
                     ADTADRYAIEPAHFTDFMASMRADLTVTDYATYADLRAYMHGSAAVIGLQMLPVLGTVT
                     ARALAAPHAAALGVAFQLTNFLRDVGEDLDRGRIYLPADLLAAHGVQRDLLLWSRRTGR
                     HDARVTAALRAAEDLTRGVYREAEPGLAMLDPVARPCIRTAFLLYRRILDTIADGGYAV
                     LHHRAVVPRRRRAAVAADGLVRVLAARLRARRTPTPVPCGGEALDVKEPR"
     gene            complement(10993..12510)
                     /gene="crtI"
                     /locus_tag="BJ961_RS20565"
     CDS             complement(10993..12510)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982461.1"
                     /locus_tag="BJ961_RS20565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_271414256.1"
                     /sec_met_domain="DAO (E-value: 6.3e-20, bitscore: 70.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTVTGRTDHVVVVGAGLAGLSAALHLLGAGRRVTVVERDPLPG
                     GRAGRREVGGYHLDTGPTVLTMPDLADEAFAAVGERLRDHVELLPLHPAYRACFADGGT
                     LDVHTGADAMQAEVERFAGAREAAGYQRLRDWLGRLYAVQMRRFIDANFDSPLGLLTPD
                     LARLAALGGFGRLDARIGRFLTDERLQRVFSFQALYAGVAPSRALAAYAVIAYMDTVAG
                     VYFPRGGMHALPRAMAAAATRAGADLRLGRDVTRLERSGARVTAVVTDHERIPCDAVVL
                     TPDLPVAHRLLGRRPRRPVALRHAPSAVVLHAGTTRTWPHLAHHTLSFGAEWRRTFDEL
                     TRTGTLMTDPSLLITRPTAHDPSLAPEGRHLHYVLAPCPNTDIGPGARAWSDLAPRYRD
                     RLLATLERRGLTGIAAAVEEECLVTPADWTAQGHAAGTPFSVAHTFAQTGPFRPRNLVR
                     GTDNAVLAGCGTTPGVGVPTVLISGKLAAARITGTPARTGTARSGRR"
     gene            12977..>13825
                     /locus_tag="BJ961_RS20570"
                     /pseudo=""
     CDS             12977..>13825
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017634.5"
                     /locus_tag="BJ961_RS20570"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="lycopene cyclase family protein"
                     /pseudo=""
                     /sec_met_domain="Lycopene_cycl (E-value: 3.7e-69, bitscore:
                     232.4, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVGAGAAGLSLAHRLPARAPHGAVPSVVLIDPPPGPLRPPRRTW
                     CFWESGPGRFDRATTASWEWLRVRGRDGAVVRRHIAPARYKMVRSDDFEALVERDLKDR
                     PGLRRLEATVGAVTGLPDATVRVAATDAAGTPVDLRARWVFDSRPPDRLPAARTRLLQH
                     FRGWFVRTERPVFDPEVVDLMDFRTAQPARGLSFGYVLPTGRHTALVEYTEFGPEPLTT
                     EAYDSALEDYTRRVLRTGATEVLSTEQGVIPMTDAVFGRRAEGCDRVFRIGVAGGATRA
                     ST"
     gene            13933..14160
                     /locus_tag="BJ961_RS36190"
     CDS             13933..14160
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017634.5"
                     /locus_tag="BJ961_RS36190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_408648756.1"
                     /transl_table=11
                     /translation="MDAVLLRALDTGRVDGPDLFFRLFDRVPAGRLLRFLDGRSRLYED
                     LAVGLRVPVLPMLRTAAELPRLPRRHLTVR"
     gene            14432..15934
                     /locus_tag="BJ961_RS20575"
     CDS             14432..15934
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144561.1"
                     /locus_tag="BJ961_RS20575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_271414257.1"
                     /sec_met_domain="DAO (E-value: 1.7e-10, bitscore: 39.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRPGPGRERVEGDPPSVAVIGGGIAGLAAATVLAERGVRVVLHE
                     REPVLGGRVAGRTFALPDGTPATMSRGFHAFFRQYYNLRSLLRRADPGLGMLTGLPDYP
                     LRHSSGLHDSFRRIPRTPPFSALAFVALSPSFGPRDLAALRPSAALPLLDVRTRRVHER
                     LDGVSAHDFLDTLRFPAAARHLAFEVFSRSFFADPRELSAAEMALMFHIYFLGSSEGLL
                     FDVPREPFPRALWDPLAGYLTRHGVEVRTSTSVEAVRPGPSGGRLVVDAAGARPYDAVV
                     LAMDVGGLRGVVRRSPHLGDDGWRGRVARLRNAPPFLVSRLWLDRPVAPGRPGFLGTSG
                     YGSLDNVSVLSHWEGEAARWAARTGGSVVELHAYAVPSAAVREVEEKRLVDQLHRVYPE
                     TRRARVVAVRHEWRADCPLFAVGGYRDRPTVRTPDPAVVVAGDLVRTDLPVALMERAAT
                     SGFLAANVLLERWGVRGETLWTVPDEGRSAPLRALARRFGQY"
     gene            complement(16155..17033)
                     /locus_tag="BJ961_RS20580"
     CDS             complement(16155..17033)
                     /NRPS_PKS="Domain: PKS_KR (9-180). E-value: 2.3e-16. Score:
                     52.1. Matches aSDomain:
                     nrpspksdomains_BJ961_RS20580_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982441.1"
                     /locus_tag="BJ961_RS20580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_271414258.1"
                     /sec_met_domain="adh_short (E-value: 4.8e-32, bitscore:
                     110.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDSPLRNRTVVVTGAARGLGAALARACAHRGARLALLGLEKPLL
                     DALAADLPTPALAVETDVTDPAALADAADETRRRLGKPSVVVANAGVAHGGPFATSDPA
                     EWRRVVDVNLTGSAHTARAFLPDLLDTAGYHLQIASLASLGAAPMMSAYCASKAGVEAF
                     NHSLRAEVAHHGVAVGIAYLNWIDTDMIRDADRYPVLRELRAHMPPPARRTFPADHVAA
                     RLVRAVERRRTAVYVPGWLRLAQVGRATLPPVVLRLSRHELPPMEAEGSLGRTGPLGAG
                     GLADRAADPGE"
     aSDomain        complement(16494..17006)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BJ961_RS20580_PKS_KR.1"
                     /evalue="2.30E-16"
                     /label="BJ961_RS20580_PKS_KR.1"
                     /locus_tag="BJ961_RS20580"
                     /protein_end="180"
                     /protein_start="9"
                     /score="52.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TVVVTGAARGLGAALARACAHRGARLALLGLEKPLLDALAADLPT
                     PALAVETDVTDPAALADAADETRRRLGKPSVVVANAGVAHGGPFATSDPAEWRRVVDVN
                     LTGSAHTARAFLPDLLDTAGYHLQIASLASLGAAPMMSAYCASKAGVEAFNHSLRAEVA
                     HHGVAVGI"
     CDS_motif       complement(16917..17006)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BJ961_RS20580_0001"
                     /evalue="4.00E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="BJ961_RS20580"
                     /protein_end="39"
                     /protein_start="9"
                     /score="16.3"
                     /tool="antismash"
                     /translation="TVVVTGAARGLGAALARACAHRGARLALLG"
     gene            complement(17086..18705)
                     /locus_tag="BJ961_RS20585"
     CDS             complement(17086..18705)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324134.1"
                     /locus_tag="BJ961_RS20585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_271414259.1"
                     /transl_table=11
                     /translation="MPDAVVVGAGPNGLVAANLLVDAGWSVTVLEEQPEPGGAVRHDGE
                     VAPGFVNDLFSSFYPLAAASPVLGGLRLQDHGLRWAHAPHVLAHPLTDGTCAVLDRDVA
                     TTAASLDAFAPGDGASWERLHEVWDRYRADILDALFTPFPPLRAGARLALRLRGAGGLR
                     LARTLVLPVRRLGEEEFRGEGGKLLLAGNALHADLAPEAAGSGGFGWLMSMLGQTYGFP
                     VPVGGSGALTDALVHRLRARGGTLRCGRRVERVLVRDRRAVAVRTAGGETVAARRAVLA
                     DVSVPALYGGLVDPVDLPDQVLTDLRHFQWDFATFKVDWALDGPVPWRCEDAARAGTVH
                     LADGLDELTRFAAQIAMRQVPDRPFSLFGQMTTTDPTRSPSGTESAWAYTHVPHDIRAD
                     AGEEGITGSWDTREQELMADRVERQVERFAPGFRALVRARRVLAPPTLQAMNANLEGGA
                     INGGTTAMHQQLVFRPVPGTGRPETPVAGLFLASAGAHPGGGVHGAPGANAARAALRQH
                     RFAGLTRVQRALTRRDRAGDRR"
     gene            complement(18698..19204)
                     /locus_tag="BJ961_RS20590"
     CDS             complement(18698..19204)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (3-141). E-value:
                     1.5e-08. Score: 27.1. Matches aSDomain:
                     nrpspksdomains_BJ961_RS20590_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031629.1"
                     /locus_tag="BJ961_RS20590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SRPBCC family protein"
                     /protein_id="WP_271414260.1"
                     /transl_table=11
                     /translation="MAVRHRLIQATTEAVWDVLADGDQYVEWVVGPSEVTPTSGQWPQV
                     GATIAYEVRLGPLRLDNESVVRRCVTGSELELEAKAGRLGTARIAVELRPWGEQCLVIV
                     DEHPLRGPGGLLHNVGVEALIQIRHRAMLARLAKLCESQAGERCRPDPSDTMGSVSYRP
                     GTGRA"
     aSDomain        complement(18782..19195)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BJ961_RS20590_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="1.50E-08"
                     /label="BJ961_RS20590_Polyketide_cyc2.1"
                     /locus_tag="BJ961_RS20590"
                     /protein_end="141"
                     /protein_start="3"
                     /score="27.1"
                     /tool="antismash"
                     /translation="RHRLIQATTEAVWDVLADGDQYVEWVVGPSEVTPTSGQWPQVGAT
                     IAYEVRLGPLRLDNESVVRRCVTGSELELEAKAGRLGTARIAVELRPWGEQCLVIVDEH
                     PLRGPGGLLHNVGVEALIQIRHRAMLARLAKLCE"
     misc_feature    complement(19387..19401)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 27.13"
                     /tool="antismash"
     misc_feature    19388..19402
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.16"
                     /tool="antismash"
     gene            19467..20636
                     /locus_tag="BJ961_RS20595"
     CDS             19467..20636
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031628.1"
                     /locus_tag="BJ961_RS20595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S1 family peptidase"
                     /protein_id="WP_271414261.1"
                     /transl_table=11
                     /translation="MRRSRLRHLALSGLLVLGTLGAVGALPASAADAPTASPSAEQPAS
                     AGLLDAMQRDFGLTRAEAADRLAAERDATGLEPVARRAAGTAFGGSWFDAEAGELTVAV
                     TSDAAPETLRAVRATGAQVRTVEHSARQLDAAKARVDRLDAPVGVSGWHVDQRAGAVVV
                     DVVEGKRADNDVQSFVKRAREAGPVTVRSVPSAPQTFAAGTVGGDPYYTGNVRCSIGFS
                     VYGGFVTAGHCGRAGAGVSGWDRSYIGTFQGSSFPDNDYAWVSVGSGWWTVPVVLGWGT
                     VSDQLVRGSNVAPVGASICRSGSTTHWHCGTVLAHNETVNYSDGSVVHQLTKTSVCAEG
                     GDSGGSFISGDQAQGVTSGGWGNCSSGGETWFQPVNEILNRYGLTLHTA"
     gene            complement(20733..21170)
                     /locus_tag="BJ961_RS20600"
     CDS             complement(20733..21170)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031627.1"
                     /locus_tag="BJ961_RS20600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_271414262.1"
                     /transl_table=11
                     /translation="MIEWVPLGSGARPVPRPVAAPLVWAGAFGGALLAVALLNGTVGSG
                     RPGLALVVLSLLAAVLGLCARFTAAPGTAVLCWLSLNGFAIPPAGTLTWTGRRDAVWLA
                     CLLGAALVGTALARLVHARAAYRRLTTATGLEAPEPGPGDL"
     gene            complement(21335..22669)
                     /locus_tag="BJ961_RS20605"
     CDS             complement(21335..22669)
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1117:
                     sodium/hydrogen exchanger"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446464.1"
                     /locus_tag="BJ961_RS20605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cation:proton antiporter"
                     /protein_id="WP_271414263.1"
                     /transl_table=11
                     /translation="MGHADTLLAMGGAFVAAAFLARLGGRIGLPTIPLFMLAGILLGPH
                     TPGFVLVEDAHDFEMLSALGLVLLLFYLGLEFHLDDLRSGGKRLLTAGGVYLLLNVGAG
                     LGFGFVLGWGVREALVLAGVLGISSSAIVTKILIDLGRIGRPETRLILGVIVVEDIFLA
                     LYLAALQPVIAGAHGVADTVLQAGKAFGFLLVLAAAARYGTRLVGRLIHTRDNELLVIS
                     FLGAAVLVAGVSEVLGVADAIGAFMVGLILAGTPSGPRIRELVHPLRDAFAAIFFFAFG
                     LAIDPGDLASVAGPVAAAAALTVVMNVVAGLCVARVYHYGSEPAAEIATTLVARGEFAL
                     ILAAMAAGAGLDARLAPFIAGYVLVLAVLGPIVAGRAHVLAAGLRAAGRLLPGTTPGPE
                     VPGGGAGKDAQTHGPSASPSDTEPEPLPASSSCSAPSSGRAEAER"
     misc_feature    complement(22725..22740)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.32"
                     /tool="antismash"
     misc_feature    complement(23134..23148)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.09"
                     /tool="antismash"
ORIGIN
        1 gaaggacatc ggcacccgcg gcgagccgag catggacacc gtcgcctccc tcgccccgga
       61 cctcatcgtc gccaccaccg acctcccgcc ggccgcggtg aagcagctgc gcgaggtcgc
      121 cccggtgatc gaggtgacgt ccgccgacgg caccggccag atcgaccgga tgctggacaa
      181 cgtcgacctc atcgcccagg ccaccggcac cacggacaag gccgaggcgc tgcgcgagga
      241 cttcgaggcc aaggtcgcgg agggcaggaa ggccctcacc gacgccgggg cggccggcaa
      301 gcccatcgcc ttcgccgacg gctacgtcgc ctccaaccag atctcgatcc gcccgtacac
      361 cgccaactcg ctcatcggcg aggtcaacga ggcgatcggt ctggagaacg cctggacggt
      421 cgagggcgac gaggcctacg gcctcggtgc caccgatgtc gagggcctga ccaagctgcc
      481 gaaggacacc cggttcgcct acatcggcaa cgacgaggac gcgagcgcca ccccgttcac
      541 cggcccgctg gccgagaacg cggtgtggaa gtcgctgccg ttcgtgaagg ccggggaagt
      601 gcaccgcctc gacgacggca tctggatgtt cggcggtccc gggtcgatgg aggcgtacat
      661 cgacgccgtc gtcggcgcgc tgacgaagta gcgaggccat ggccgtcacc gcaaccgaac
      721 ccacgaccga tccggcggcc cgtccgccgg cggcccccac gtcccggtcg ggcgcggccg
      781 cggtgacggc cgggatcgtc ctgctggtcg ccgtactcgc cgtcgtcgac atcacccagg
      841 gcaccgccgc cgtcggaccg tccgaggtcc tcaaggccct gaccgggcag gccgccgcgg
      901 acgacgcgtc cgtcgtcgtc gcctcccggc tgccccgcat gaccgccggg ctcctggtcg
      961 gcgccgtcct gggggcggcc ggcgccgtgc tccaggcggt cagccgcaac gtactcgcct
     1021 ccccggacac cctcgcggtg aacgcgggtt cctacctggc gctgggactg gtgggcgcca
     1081 ccggcgtctc actgccgatg atcgcctcct ccggcgtcgc cttcgcgggc ggtctggcgg
     1141 cggcggccgt cgtgctcgga ctgtccggcc tcggcacggg caccgtccgc ctcgtgctgg
     1201 ccggcaccgc gctgatgctg ggcctgaact ccatgacgca ggcgttgctg ctgctcttcc
     1261 cggagcagac gaagggcctc tacgagtgga accagggcag catcgcccag aacggcttcg
     1321 acggcgtcct gcagatgctg ccgatcgccc tggccggcct ggccgggctg atgctgacgg
     1381 ctcgccgggt ggacgcgctg gctctcggcg acgacaccgc gcgcggtgtc ggcgtcccgg
     1441 tgcgggccac ccgcgtcacg gtcgtcgtgc tcgcggcgct gctgtccgcc gccgcggtca
     1501 ccctcgccgg gcccatcggc ttcgtcggcc tgtgcgcccc cgccctggtg cgtccgctcg
     1561 cccgacggtt tcgcggcctc acccgctccc gtacggccgt gcccgcggcg gcgctcaccg
     1621 gcgcggcgct ggtgctcggt tcggacgtgc tgctgcgggc cctgatcgcg gacccgcgcg
     1681 cggtgtccgt gcccacgggt gtggtcacca gcctggtcgg cgccgtgttc ctggtcgcca
     1741 tggcactgcg ggtgcgggac accgccgggg ccggggcgcc ggaccggctg cggacccccg
     1801 gccggggagt cttcctggcc acgctcaccg ccctggccgt ggtcctggtg gggctcgtga
     1861 tcgccgccgt gctggtgggc gacagcaagc tgctgctggg tgacgtggtc aactgggccc
     1921 agggccaggc cgggcggacc gtctccttcg tactggacac gcgggtgccc cgggtgctcg
     1981 ccgcgctctc ggcgggggcg gcgctcgccc tggcgggcac cctcgtgcag gccgtcaccc
     2041 gcaacccgct cgccgaaccg aacgtcctcg gcgtgaccgg cggtggcgcg ctgggcgcgg
     2101 tgatcctggt gaccaccgtg ccggccgccg ggacgtgggg cgtcgccggt gccgcgttcg
     2161 cggggtccgc ggtcaccgcg gtcgtcgtct tcggcctcgc cgcccggggc ggtttccggc
     2221 agaaccggct ggtcctcgtc ggcatcggcg tggcgtccgg gacggcggcg ctgatcagcc
     2281 tgctgatcgt gctcaccgac ccgttcaacg ccaacaaggc gctgacctgg ctgtcgggtt
     2341 cgacctacgg gcggaccatg ccggacgtcg tgccggtggc gctggccctg gtcgtcggca
     2401 tcggcgtggc cgtcgcccgg cgcaccgagc tggacctgct ctcgctggac gaggacacgc
     2461 cgcggctgct cggcctgcgg ccggctcggg gccgcctcgg gttcctggtg ctgagcgtcg
     2521 tcctcagttc gaccgccgtg gcctgcgcgg gcacgatcgg cttcgtcggc ctggtcgccc
     2581 cgcacgcggc acgcgccctg gtgggccggc ggcacgtgcg ggtggtgccg gtcgcggtcc
     2641 tgctcggcgc cacgctggtg tgcgccgccg acctgctggg ccgtacggtg atcgccccgg
     2701 cccagctcgg cgcgggcctc atgacggcgg tgatcggcac gccgtacttc ctgtacctgc
     2761 tggtgcggag ccgtcgctag acgacgccgg gaaggaaaac cgggtgctcc cgggaccgcg
     2821 gcccccgtac ggtgccggta tggaccggcg cggcgcggac gggggccacg cgggcctgct
     2881 gaacgtcatc gatctggagg ccacctgctg ggacgggcag ccgccgcccg gcgcggtgag
     2941 cgagatcatc gagatcggtc tcgccgtggt cgacctcgac gcccgggagc gggtggcccg
     3001 gcaccggatc ctggtgcggc cggtccgctc ccgggtcggc gcgttctgca cggagctgac
     3061 cggtatcacc caggccgagg ccgaccgggg cgtgagcctc gcccgggcct gcgacacgct
     3121 gacgcgcgaa cacggcgcgg gcgcgcggcc ctgggcgagc tggggcgact acgaccgcga
     3181 gcagttggtc cgccagtgcg cggccgacgg ggtgcccttc cccttcggcc gcccggccga
     3241 gcgcgcgcac accaacgcca aggcggtctt caccgaggcc cacgggctgc gtcggcgccc
     3301 cggcatggcg cgggcgctgg agatcgcggg gctgccgctg gaggggcggc atcaccgggg
     3361 cgtggacgac gcctggaaca tcgcggcgct ggtgctgcgg ctggccgccc aggacgcctg
     3421 gccgggctct tgttagacgc gacgtcaagt tactgaaccg taatgaacaa ggtgctaccc
     3481 ctggtaaccc ctgcccggtt acggtccggt aaccccacag gagcagcgcg accgcggtcc
     3541 ggccccacga ggccgcggac gaccggatcc ggcccttccc caggaggttc gccatgcccc
     3601 cacgtccacg catgctcgcc gcggcgatcg ccgccgcact cgccctcggc gcgcaggccg
     3661 tccccgccgt cgcggccgac ggaccggccg gcgactcgac gaccacgacg tcccgcggtg
     3721 tcgagatacc cgccttctac accccgccgt ccgaactccc cggcgccgac ggcgcgctgg
     3781 tccgcagcga gccgctcccc ctggcgctca gcctgcccgg cgtcgacggc ccgcttcccg
     3841 gccgggcgac ccggctgatg tacaagtcca ccgacgcgaa cggcgaggcg gtcgccgtca
     3901 ccggcgccta catcgagccg gccgcgaagt ggcgcggcga gggcccgcgg cctctggtcg
     3961 ccgtcgcgcc cggcaccatg gggcagggcg accagtgcgc cgcctcgatg gccctggagc
     4021 acccgctgca gctcaacggg cagacggtct cggtcggtta cgaggacctg tccgtctacc
     4081 ggctcctgct gcgcggcgtc gcggtcgtcg tcaccgacta cgtgggcctc ggcaccaccg
     4141 accgcctgca cacctacgtc aaccgcgtcg acggggccca cgcggtgctg gacgccgtac
     4201 gcgccgcccg ctccctcgac tcggcgtccg tcaccgccga gtcccgggtg gggctgttcg
     4261 ggtacagcca gggcggcggc gccacggcgg ccgcggccga gctccagccc tcctacgccc
     4321 ccgacgtcga gctggccggt acctacgccg gcgccccgcc cgccgacctg acgaaggtga
     4381 cggaggcgat cgacggcagc gacctggcgg gcgcgctcgg ctggtcgctc aacggcttcc
     4441 tgcagaccga gccggccctg cggcccatcg ccgaccggta cgtcaacgag gcgggccggg
     4501 aggcgctgaa ggacctgtcg accatgtgcg tgggcgacgc cctcttcggc tacggcggcg
     4561 acagcagcac ggactggacg aagaccgggc agtccctcgg cgacatcatc cgggccgagc
     4621 ccgcgctcca ggacttcctg gccgagcagc gcatcggcgc gctcaagccc gcgggaccgg
     4681 tccgtgtggc caccggcacc agcgacgatc tggtccccca cgggcaggcc cgacggctgg
     4741 ccgtcgactg gtgcgacaag ggcgcgaagg tcacctacgt ccccgtgctg ctgccgggcg
     4801 tgggcagcgg cctgctcaac cacttcgccc cgctgctcac cgaccagggc aacgccatct
     4861 cctggctgac cgaccggctc gagggcgagg cggccggctc caactgctgg agcatgccgg
     4921 tacagccctg agccgtaccg caccgccgcc gcccggggca tccgcgccgc cccgggcagc
     4981 ggctccggca tgcgcccctc ccgtgttgcg gcacagaatt cgctcaggcg aactgtggcg
     5041 gagcgacagg aaggcagcgg cgtggtcgac gcgaagcccg acggcgggtc cggtccccgg
     5101 agcgggaaga agatgccgag ctcggtcgcg cacctgccgc ggcaggtgcg cgaggagctg
     5161 gcccgccggc tccgccgcac caagcgggcc tttcgcgagg aggacgtcca ggtcgtcgag
     5221 aaacccctcc tcaagcgcgc ggtcggggcg tcggcgctgg gcaactgcat ggagtggttc
     5281 gacttcgggg tctacagcta tctggccgcc accatcggca aggtgttctt ccccggcgcc
     5341 tccccggccg cccaggtcat ctcctccttc gccaccttcg ccgcggcctt cgtcgtacgc
     5401 ccgctcggcg gcctgttctt cggcccgctc ggggaccgcg tcggccggca gaaggtactc
     5461 gccaccacca tgatcatgat ggcgctcggc accttctcca tcggtctcat ccccagctac
     5521 gccaccatcg gcgtcgccgc cccgatcctg ctgctgctcg cccggatggt ccagggcttc
     5581 tccaccggcg gcgagtacgg cggcgcgacc acgttcgtcg ccgagtactc acccgaccgg
     5641 cggcgcggct tcctgtccag ttggctcgac ttcggcacct tcgtcggcta cgccctgggc
     5701 tcggccctgg tcaccgtgct gaacctgtcg ctgaccgacg cccagatgct gcactggggc
     5761 tggcggctgc cgttcctgat cgccggtccg ctcggcatca tcggcctgta catgcggctc
     5821 aagctggagg agtccccggc cttccagcag cagctggacg agcacgagaa gggcctcgcc
     5881 caggagtcgg cgggcagcga gttcaagacg atcgtgcgcg agcactggcg cccgctgctc
     5941 gtctgcatgg gcctggtgct gctctacaac gtcaccaact acatggtcac cggctatctg
     6001 ccgacctacc agacggagac cctggaccgc tccagcggct tcgcggacgt gctcgtgctg
     6061 atcggcatgg tgtggatcgt gctgctgatc accttcctcg gccggctcag cgaccacgtc
     6121 ggcagacgtc cgctgtacgc ggtcggcgcc gcggcgatga tcgtcctcgc gatcccggcg
     6181 ttcctgctgc tgagggcgga cggcgtctgg gtgccggtcc tcggggtgct gctgctgtcc
     6241 accctgctgg cctgcttcgc cgcgcccagt gccgccacgc tgccggcgct gttcccgacc
     6301 gcggtgcgct acgcggccat ggccatcggc ttcaacttcg ccgtcgcggc cttcggcggc
     6361 accacgccgc tggtcgccga ggcgctggtg agcatcagcg gcgacgaact gatgcccgcc
     6421 tactacctga tggtggccgg tgccatcggc ctggtgaccg tgaggttcct gccggagagc
     6481 gcccaggtgc cgctgcacgg ctcgcagccc atggtcggat cccggcagga gcagcgtgag
     6541 ctgatcacca cctcgaagga cctctacagc ttctccaagg accgctcgaa ggcctcctga
     6601 cgccccgccg cgggccgtcg tcgtccgcgg gtgaacggaa gggacacgcc cgagccgacg
     6661 gcgaccccgg cgaagaccag ggcgctgccc acggcctggg cggcgccgta ggaacccgtg
     6721 ccgacgagcg gcgccgtgca ggcggcggcg accgggatca gtccggagaa cagggtggcg
     6781 cgctcggcgc cgatccgctg catgcccatg taccagcaca cgaacccgac gacggtgacc
     6841 accaccgcct gccacagcag cgcgcccgcc tcgacggcgt cgggccgccg cagccacccg
     6901 gcaccgtcgg ccagcacacc cacgaccgcc gactcggccg cggcgacgcc gcacaccacg
     6961 gtggacagca gtcgcgggcc caggggacgc agtacgggca cggcgaggac ggcgaaaccg
     7021 acctcgccgg ccagcgcgca cacggagaag gcgatgccga cgccgtcggt gcgcccccag
     7081 ccctggaccg tgaaggcccc tacggccacg aacaacgccc cgtacaggac gatccgttgc
     7141 ggcccgcgtc cctccaggag ggggacgagg acggcgacca ccacgggcgc gcagcccacg
     7201 aagacgccgg gcaccgcggg ttccgccgtg cgttcggcgg cgaggacggc caggttgaag
     7261 ccgaccatgc ccacggccgc cagcagggcc aggcgcagcc accggcccgt gccgagcgcc
     7321 cgcaaccggg ccgtcgcacc gggcccggcc aacgggacga ggagcaggaa ggccagcccg
     7381 tagcgcagga actggccgcc cgcgtagggg tagtcgccga gcaggctgtt ggcggtgaag
     7441 gagccgccga cgaggacaca ggcgagcgcg gcgagcaggg tcccgcgcgt ggtggtggcg
     7501 ttcatgacca cgacgctaga gagcgcggcg gtccaccacg gggtccactt cgggtgcgct
     7561 gtcggggacc aatcggcgac gagggccgct cacacgcccg tcacgacttc ttcatcacgt
     7621 gcatgccacg gaaatcgcgg gtagtcggag agtcccgatg ccaacacatc gggacagcaa
     7681 gggatttgac ggagatgaaa cgatatggga ggtacttcca gtgcgcaccg gcaaaggggc
     7741 aaccgctgtg gcgaccgcga gcgtctgtgt cgccctactg gccggctgcg gcggtgattc
     7801 gggcgacgag ggcgaggcgt tcgaggggca gagcgccgac gacatcgccg cgaaggccgt
     7861 cgaggccacc cggcaggcga agtccatgca cgtgaagggc gacacgcgtc tggaggacgg
     7921 gagcaccgtc accattgacg tctcggtcga ccaggagaag aactgcgagg gcaccatcgg
     7981 cgccggcggg accgaggcgg acgtacgcca caccgacgcg accctctacc tgcgcggtga
     8041 cgagcggtac tggcggaccg cgctgaagca gcagcccgac gcggcccgca agatggtgcc
     8101 cgagctccgg gacaagtggg tgaagatgcc ggcgaacgac gccacgaccg ccggggtctg
     8161 cgacaagcag ggtttcgtcg ccgccatgga cgaggacgag tcggagcgcc ggggcatgaa
     8221 gcgcggctcc acgacggacg tgaacggcgc gaaggccctg gagctgacca aggacgcctc
     8281 cggcggcgag aagctcacgc tgtacgtcgc gacggagggc gagccgtacc tcctcaagac
     8341 cacgaccgag ggcggcaaga accccggcag cgtcacgttc ggcgagtacg gcgagacggt
     8401 ggatcccgaa cagccgccgg ccgccgagac ggtcgacatg aaggacctcg cgggcgggca
     8461 gcgggcctga cggcctcggg cccaccgtcc taggcgtccc cgcgctcccg gtccgaactc
     8521 ggccacacgt agggcaggtc gtccgggacc cccgggaaca gctcggcgta cacctcgggt
     8581 tccttgcgca ccagggccga gcggtggctg cggtggaagg cctcgtcgcc gagccaggga
     8641 ggcagttctc cggcggccgc cagctccggc tggtcccgca ccggctcccc cggccggctc
     8701 tcggcgagcc ccgcgaccag tgacgccgcg cagctgtcct ggtggccctg ctcgcgccag
     8761 acccggcaga cgtcgaggcc gtagcggacc agtgcctcct cgtagcccgt ccacatccgc
     8821 accgccgggt gccggcgcca gccgtagccg gggacggtga gtccgcgcag cacctggagc
     8881 gcctcgacgc gctgtttgcc gaggcggcgc cggtccaggg ccagggccga ctcccggaag
     8941 ccggggtggg ggaggaaggt ctgcatcgcg atgccgctcc gttcagccgg ggaaccggcc
     9001 gcgggcacgc aggtgtccgc ggcgttcggc gtaggcgagg tcgtcgcgcc acaggcggcc
     9061 cgcggcggcc cgcatcagca ggcgcagggc cggtgcgagg cggcgggcca gggggaagcc
     9121 gggccggtcc gaggtggcga gcaccgcctc gacgaccgcc gtgcgcggcc gcccgctcgc
     9181 gtccggtccg agcggcgtgg cgtggctctc cacgaccgac cccgcgccct cgccctcggt
     9241 gatgcgcatg acgacggtgc ggggtccggg ggcggtgaac tcggcccgta cgggcacgac
     9301 caggcggccg gtgagccgga aggagacgtc cacgacgaag cggtcgccgt tcccgtcgtc
     9361 gtgcggggtc tcgccgggtg tcccgacgac ggtgaggtcc acgaaggagt acgggtggaa
     9421 ccaggcgccg tgccacgggt cgagccggtt ggcgaccacg tcctcgggct cgcaggtccc
     9481 cgctccccgc cacacggacg tcagggccgt cgcccggggc ggccggtcgg gcacgagggg
     9541 ggccggggtc ggcggctcct cccccacggt gtccagccgt gcccacacca gtacgccgtc
     9601 gtcgtggacc ggcaggggtt cccagccggc gaacggggcg ccgtccaggg cgagtccgtg
     9661 ccagtggcac acgagcgtgc cgcaccgcac cgggctgtcg gccagcggcg ccccgaggtg
     9721 ggggcaggcg ccggggccgc ccaccagtcg cccccgcgcg tcccgccaga cgacgacctc
     9781 gacgccctcg acggtgccgg acagcgggcg tgtgggacgt acgtcggtgc tcgcgccgag
     9841 gacgtaccag ttgcccgagg ggcgggcctc ggcccgcttg agggcggcgg cgatgacggc
     9901 ggggcgcgcc tcgcgccacg tcggccgctg ccgttcccag gggacggcgc ggcggcgcag
     9961 ccgcagggga ggcgtcctcg gcgggggcgg gggtccgggc tcatcggggc tccttcacgt
    10021 cgagggcttc gccgccgcac ggcacgggcg tcggcgtgcg ccgtgcgcgc agccgggccg
    10081 ccagtacgcg tacgagcccg tcggcggcga cggccgcgcg gcgtcggcgg ggcaccaccg
    10141 cacggtggtg cagtaccgcg tacccgccgt cggcgatggt gtcgaggatc ctccggtaga
    10201 gcaggaacgc ggtgcggatg cagggacggg cgacggggtc gagcatggcc agtccgggct
    10261 cggcctcgcg gtagacgccc cgggtgaggt cctcggcggc ccgcagcgcg gcggtgacgc
    10321 gcgcgtcgtg gcggccggtg cgcctgctcc agagcagcag gtcccgctgg acgccgtgtg
    10381 cggccagcag gtcggccggg aggtagatcc ggccgcggtc gaggtcctcg ccgacgtcgc
    10441 gcaggaagtt ggtcagctgg aaggcgacgc ccagggcggc ggcgtgcggg gcggccaggg
    10501 cgcgggcggt cacggtgccg aggacgggga gcatctggag gccgatgacg gcggccgagc
    10561 cgtgcatgta ggcgcgcagg tcggcgtagg tggcgtagtc ggtgacggtg aggtcggcgc
    10621 gcatggaggc catgaagtcg gtgaagtgcg ccggttcgat ggcgtaccgg tcggcggtgt
    10681 cggccagggc gagcaccacg ggctcgtcgg tcggtccgcc gccggtgagc gaccgccgca
    10741 gcagccggtc gaggcgggtg agggcggcgg cacgctcggc gggcgtggcg tcggctgccg
    10801 tgtcgtcgac gatgtcgtcc gcccaccggg cgaatccgta cagggcgtgc acggcgggcc
    10861 tgcggtcggc gggcaggagg cgggtggcca ggaagtaggt gcggccgtgg cgggcgttga
    10921 ggagccggca ccgggtgtag gcggcgcgca gtgccgggtc ggtgatgccg gcggcgtcga
    10981 gttcgcgtcc ggtcatcggc gcccgcttcg tgccgtgccg gtgcgggccg gtgtgccggt
    11041 gatgcgcgcg gcggccagtt tcccggagat cagtacggtc ggtacgccga cgcccggggt
    11101 ggtcccgcag cccgcgagga ccgcgttgtc ggtgccgcgc accaggttgc ggggccggaa
    11161 gggcccggtc tgggcgaagg tgtgggcgac ggagaacggg gtgcccgcgg catgcccctg
    11221 cgcggtccag tcggcggggg tcaccaggca ctcctcctcc acggcggcgg cgatgccggt
    11281 cagtccccgg cgttccaggg tggcgagcag gcggtcgcgg tagcggggcg cgaggtcgct
    11341 ccaggcgcgg gcgccggggc cgatgtcggt gttggggcag ggcgcgagga cgtagtggag
    11401 gtggcggccc tcgggggcga gggacgggtc gtgggcggtg ggccgggtga tcagcaggga
    11461 cgggtcggtc atgagggtgc cggtcctggt cagctcgtcg aaggtccgcc gccactcggc
    11521 gccgaaggag agcgtgtggt gggcgaggtg cggccaggtg cgggtggtgc cggcgtgcag
    11581 gacgacggcg gagggcgcgt gccgcagggc gacggggcgc cgcgggcgtc ggccgagcag
    11641 ccggtgggcg acgggcaggt cgggggtgag gacgacggcg tcgcacggga tgcgctcgtg
    11701 gtcggtgacg acggcggtga cgcgggcgcc ggaccgttcc aggcgggtga cgtcccggcc
    11761 gaggcgcagg tcggccccgg cgcgggtggc ggccgcggcc atggcgcggg gcagggcgtg
    11821 catgccgccg cgcgggaagt agaccccggc gacggtgtcc atgtaggcga tgacggcgta
    11881 ggcggccagc gcccgggagg gcgcgacacc ggcgtacagg gcctggaagg agaagacgcg
    11941 ttggaggcgt tcgtccgtca ggaaccgtcc gatgcgggcg tccaggcggc cgaagccgcc
    12001 gagggcggcg agccgggcca ggtcgggggt gagcaggccg aggggtgagt cgaagttggc
    12061 gtcgatgaag cggcgcatct gcacggcgta cagccgcccg agccagtcgc gcagccgctg
    12121 gtacccggcc gcctcccggg ccccggcgaa gcgttcgacc tccgcctgca tcgcgtcggc
    12181 cccggtgtgc acgtccaggg tgccgccgtc ggcgaagcac gcccggtagg cggggtgcag
    12241 cggcaggagt tcgacgtggt cgcgcagccg ctcgccgacg gccgcgaagg cctcgtcggc
    12301 caggtcgggc atggtgagca cggtcgggcc cgtgtcgagg tggtagccgc cgacttcgcg
    12361 ccgcccggcc cggccgccgg gcagcgggtc gcgttcgacg accgtcaccc gccgtccggc
    12421 acccagcaga tgcagggcgg cggacaggcc ggcgagcccc gcaccgacga cgacgacgtg
    12481 gtcggtgcgg ccggtcaccg tccgcgtcat cgggcgcctc cgaccgcgcg ggtctcactc
    12541 ggctgcgggc tgccgtcgcc ggccgtgctg gggcgcatcg cggttcctct cgtcgccggc
    12601 cgcggcggtg agccgtgccg ggtgtcccgg ccgcgggccg aaggcgcggt ccgcgccatg
    12661 ctttccctct tcgcccgtgc cacgccgccg caaggcccgt acccacccgg cagtcacccg
    12721 ttcggcgggt accccggccc ccggcgggca cccgtgccgc gccgcccagc gcgccgtgcg
    12781 accgcggacg ccgccggggc ggaatactcc ccggaccggc gcggaccggc gcggaccggc
    12841 gcggaccggc gcggaccgga gcggaccggc gcggaccgga gcgggccgga agggaccgag
    12901 gcggaccgga ccgctccgaa cgggccgctc cgaacgggcg aacgggaagg aggcgggtgt
    12961 ggtcgacacg gacatcgtgg tcgtcggcgc aggcgccgcg ggtctctccc tggcgcaccg
    13021 gctcccggca cgggcgccgc acggtgcggt gccctccgtc gtcctgatcg acccgccgcc
    13081 gggaccgctg cggccgccgc gtcgcacctg gtgcttctgg gagtccggcc ccggccgctt
    13141 cgaccgggcg acgacggcgt cctgggagtg gctgcgggtg cgcggccgcg acggggcggt
    13201 cgtccggcgg cacatcgcgc ccgcccgcta caagatggtc cgctcggacg acttcgaggc
    13261 gctggtggag cgggacctga aggaccgtcc ggggctgcgg cgcctggagg ccaccgtggg
    13321 cgcggtgacc ggtctgccgg acgccaccgt acgggtggcg gccacggacg ccgcggggac
    13381 accggtcgac ctgcgcgccc gctgggtctt cgactcccgt ccgccggacc ggctgccggc
    13441 cgcccgcacc cgcctgctcc agcacttcag gggctggttc gtccgcaccg agcggccggt
    13501 cttcgacccc gaggtggtcg acctgatgga cttccgcacc gcacagccgg cgcggggcct
    13561 gtccttcggc tacgtgctgc cgaccggacg gcacaccgcg ctggtcgagt acaccgagtt
    13621 cggccccgag ccgctgacga ccgaggcgta cgacagcgcg ctggaggact acacgcgccg
    13681 cgtcctgcgc accggcgcca cggaggtcct gtcgaccgag cagggggtca tcccgatgac
    13741 cgacgccgtc ttcgggcggc gggccgaggg ctgcgaccgg gtcttccgga tcggcgtcgc
    13801 gggcggcgcg acccgggcgt ccaccggcta cacgttcgcc gccgtgcaac ggcagtccgc
    13861 ggccgtcgcc cgcgcggtgc gcgcgggccg ccgcccggtg ccgccacccc gcatccggca
    13921 cgggcccggt ggatggacgc ggtgctgctg cgcgcgctgg acaccggccg cgtcgacggc
    13981 cccgacctct tcttccggct cttcgaccgc gtacccgccg ggcggctgct gcgcttcctc
    14041 gacggccggt cgcgactgta cgaggacctc gcggtcggcc tgcgcgtccc cgtcctgccc
    14101 atgctgcgca cggcggccga actgccgcgg ctgccgcgcc gccacctcac cgtccgctga
    14161 acgccgtccg ccgacccacc accccggagc ccccgatgcg cccgatgccc ctgccgcccg
    14221 acgccgcgcc gaccgccgcc cccgagctcg gggcgggcca ccgccaccgg tccgtcacgc
    14281 tccctccggg ccaccacacg cagtgccccg gcaccggaga cgcgcggtga tccggcgggg
    14341 tgcgggcagc cgtggcggtg ggggtggacg gagcgacgcg ggtggccggg gtggtgaagg
    14401 gcgaccgccc gggcgggacc ggcgggcacg ggtgctgcgt ccgggacccg ggcgtgagcg
    14461 ggtcgagggc gatcctccgt cggtggcggt gatcggcggc ggcatcgcgg gcctcgcggc
    14521 ggcgacggtc ctggcggagc gcggggtgcg cgtcgtgctg cacgaacgcg aacccgtgct
    14581 cggcggccgg gtcgcgggcc ggacgttcgc cctgccggac ggtacgcccg ccacgatgag
    14641 ccggggtttc cacgccttct tccgccagta ctacaacctg cggagcctgt tgcgtcgcgc
    14701 cgatcccggt ctgggcatgc tgaccggtct gccggactat cccctgcggc acagcagcgg
    14761 gctgcacgac agcttccgcc ggatcccccg cactcccccg ttcagcgccc tcgccttcgt
    14821 cgcgctgagc cccagcttcg ggccgcgcga cctggcggcc ctgcggccct cggccgcgct
    14881 gccgctcctg gacgtccgca cccgccgcgt ccacgagcgc ctggacggcg tcagcgccca
    14941 cgacttcctc gacaccctgc gctttcccgc cgccgcgcgg cacctggcct tcgaggtgtt
    15001 ctcccgcagc ttcttcgccg acccgcgcga gctgtcggcc gcggagatgg ccctgatgtt
    15061 ccacatctac ttcctcggct ccagcgaggg actgctgttc gacgtaccgc gtgagccgtt
    15121 cccgcgggcg ctgtgggatc ccctcgccgg gtatctgacg cggcacggtg tcgaggtccg
    15181 cacgagtacg tccgtcgagg ccgtccggcc gggtccgtcc ggcgggcggt tggtggtcga
    15241 cgccgccggc gcgcggccgt acgacgccgt ggtgctcgcg atggacgtcg gagggctgcg
    15301 gggtgtggtg cgccgttcgc cgcacctcgg ggacgacggc tggcgcgggc gggtggcgcg
    15361 gctgcggaac gctccgccgt tcctggtctc ccggctgtgg ctggaccgcc cggtcgcccc
    15421 cggccggccc ggattcctcg gcacgagcgg gtacggctcg ctggacaacg tcagtgtgct
    15481 gtcccactgg gagggcgagg cggcgcgctg ggccgcgcgc accggcgggt ccgtcgtcga
    15541 actccacgcc tacgccgtgc cgtcggccgc cgtccgggag gtggaggaga agcggctggt
    15601 cgaccagttg caccgcgtgt acccggagac ccgtcgggcc cgggtggtcg ccgtgcggca
    15661 cgagtggcgg gcggactgcc cgctgttcgc cgtcggcggc taccgcgacc gccccacggt
    15721 ccgcaccccc gacccggccg tcgtcgtcgc cggggacctg gtccgcacgg acctgcccgt
    15781 ggcgctgatg gagcgcgccg ccacctccgg cttcctcgcc gccaacgtcc tgctggagcg
    15841 gtggggcgta cggggcgaga cgctgtggac ggtgcccgac gagggccggt ccgcaccgct
    15901 gcgggccctg gcccggcggt tcgggcagta ctgaggagcg cgcgccggac ccgtcctgac
    15961 gggggcccga cgccggatcc gtcctgacgg agcgcccgac gccggggccg gcttcacgaa
    16021 gcgcgcgacg ccgggcccgt gctcacggag cgcgcaccgt gccgggcccg gcctcccaga
    16081 gcgcaccgca tcgggcccgc ctcacagcgc gcaccgctcc gggcccggcc tcacgaagcg
    16141 cgctgctcgg ttcgctactc ccccgggtcg gccgcgcggt cggccagtcc gcccgcgccg
    16201 agtgggccgg tgcggcccag ggagccctcg gcctccatcg ggggcagttc gtggcgggac
    16261 agccgcagga ccacgggcgg cagggtcgcc cgccccacct gtgccaggcg cagccagccc
    16321 ggcacgtaca cggcggtacg gcggcgctcc acggcgcgga ccagccgggc ggccacgtgg
    16381 tccgccggga aggtgcggcg ggccgggggc ggcatgtggg cgcgcagttc gcgcaggacc
    16441 gggtaccggt cggcgtcgcg gatcatgtcg gtgtcgatcc agttgaggta ggcgatgccc
    16501 acggcgaccc cgtggtgggc cacctcggcg cgcagcgagt ggttgaaggc ctccacgccc
    16561 gccttggagg cgcagtacgc gctcatcatg ggggcggcgc cgagcgaggc cagcgaggcg
    16621 atctggaggt ggtagcccgc ggtgtcgagc aggtccggca ggaaggcgcg ggccgtgtgg
    16681 gcgctgccgg tgaggttcac gtcgacgacg cggcgccact cggcggggtc cgaggtggcg
    16741 aacggtccgc cgtgcgcgac accggcgttg gcgaccacga ccgacggttt gcccagccgc
    16801 cggcgtgtct cgtcggccgc gtcggccagc gcggcgggat cggtgacgtc ggtctcgacg
    16861 gcgagcgcgg gggtcggcag atccgccgcc agcgcgtcca gcagcggctt ctccaagccg
    16921 agcagggcga gtcgggcgcc gcggtgggcg caggcgcggg ccagggcggc gccgagtccg
    16981 cgcgcggcac cggtcacgac gacggtgcgg tttcgcaggg gactgtctgt caccggtcgg
    17041 ccctccctgg gagtcgtccg cgtccgcgcg gacggtcgtc ggcgttcacc ggcggtcgcc
    17101 ggcccggtcg cggcgggtga gggcccgctg gacccgggtg aggcccgcga accggtgctg
    17161 gcgcagtgcg gcgcgcgcgg cgttggcgcc gggcgctccg tgcaccccgc ctcccgggtg
    17221 ggcgcccgcg gaggcgagga agagaccggc caccggtgtc tccggccgtc cggtaccggg
    17281 cacgggccgg aagacgagtt gctggtgcat ggcggtggtg ccgccgttga tggcgccgcc
    17341 ctccaggttg gcgttcatgg cctggagcgt gggcggggcc agtacgcggc gggcccgcac
    17401 cagggcgcgg aagccgggcg cgaagcgttc cacctggcgt tcgacgcggt cggccatgag
    17461 ttcctgttcc cgggtgtccc agctgccggt gatgccctcc tcgcccgcgt cggcgcggat
    17521 gtcgtggggg acgtgggtgt aggcccaggc ggactcggtg ccgctcggtg agcgggtggg
    17581 gtcggtggtg gtcatctggc cgaacagcga gaaggggcgg tcggggacct gccgcatggc
    17641 gatctgggcg gcgaaccggg tcagttcgtc gaggccgtcg gcgaggtgca cggtgccggc
    17701 ccgcgccgcg tcctcgcacc gccagggcac gggtccgtcc agtgcccagt ccaccttgaa
    17761 ggtggcgaag tcccactgaa agtgccgcag gtcggtgagg acctggtccg gcaggtccac
    17821 cgggtcgacg agcccgccgt agagggcggg tacggagacg tcggcgagga cggcccgccg
    17881 ggcggcgacg gtctcgccac cggcggtgcg cactgcgacc gcgcgccggt cgcggaccag
    17941 gacgcgctcc acgcgccgcc cgcagcgcag ggtgccgccg cgggcgcgca gccggtggac
    18001 cagggcgtcg gtgagggcgc cggatccgcc gaccggtacg gggaagccgt aggtctggcc
    18061 gagcatcgac atcagccagc cgaagccgcc gctgcccgcc gcctccggcg cgaggtcggc
    18121 gtgcagggcg ttgccggcca ggagcagctt gccgccctcg ccccggaact cctcctcgcc
    18181 caggcggcgc accggcagga ccagggtgcg ggcgagcctg agtccgcccg cgccgcgcag
    18241 ccgcagggcc agccgggcgc cggcgcgcag gggcgggaag ggggtgaaga gggcgtccag
    18301 gatgtcggcg cggtagcggt cccacacctc gtgcagccgc tcccaggagg cgccgtcgcc
    18361 gggggcgaag gcgtcgaggg aggcggcggt ggtggcgacg tcgcggtcga ggacggcgca
    18421 ggtgccgtcg gtcagggggt gggccagtac gtggggcgcg tgggcccagc gcagcccgtg
    18481 gtcctgcagg cgcaggccgc cgaggaccgg ggaggcggcg gcgagcgggt agaaggagct
    18541 gaacaggtcg ttgacgaagc cgggggcgac ctcgccgtcg tggcggaccg cgccgcccgg
    18601 ctcgggctgc tcctccagga ccgtcacgct ccagccggcg tccaccagca ggttcgccgc
    18661 caccagtccg ttgggtccgg ctccgaccac gacggcgtca ggcacggccg gttcccggcc
    18721 ggtacgacac ggatcccatc gtgtccgacg ggtcgggccg gcaccgctcg ccggcctggg
    18781 actcgcagag cttggcgagc ctggcgagca tggcgcggtg ccggatctgg atcagcgcct
    18841 cgacgccgac gttgtgcagc agtcctcccg ggccgcgcag cgggtgctcg tccacgatca
    18901 ccaggcactg ctcgccccag gggcgcagtt cgacggcgat gcgggccgtg ccgagtcggc
    18961 ccgccttggc ctccagctcc agttccgagc ccgtcacgca gcgtctgacc accgattcgt
    19021 tgtccagccg cagcggtccg agccgtacct cgtacgcgat cgtcgcgccg acctgcggcc
    19081 actgtcccga cgtgggggtg acctccgagg gcccgaccac ccattccacg tactggtcgc
    19141 cgtccgcgag gacgtcccag acggcctccg tcgtcgcctg gatgagcctg tgccgaaccg
    19201 ccacgtgtgc ctccaaggtc cagtggccgt catgtggccg ttttcgcgtg accgcagcct
    19261 gagtgccccg tccgcgaccg gccaaccggg gagacggacc gcaggggccc gggggcggct
    19321 gcacggaaag gccgtgcatt ggcatggacc tgataacggg ttgctggcta agctcgaagc
    19381 gacccgatga gagcgctctc aaaccgcggt tgttccatgc catctgttcc gcccccacct
    19441 tgctggaacg acgaagggca actcccgtga gacgcagcag actcaggcac ctcgccctgt
    19501 ccgggctcct cgtgctcggc accctcggcg cggtcggcgc gctgccggcc tcggcggccg
    19561 acgcccccac cgcctccccc tccgcggagc agccggcctc cgccggtctc ctggacgcca
    19621 tgcagcggga cttcggcctc acccgggccg aggccgcgga ccggctggcg gccgaacgcg
    19681 acgccaccgg cctggaaccc gtggcacgcc gggccgccgg aacggccttc ggcggctcgt
    19741 ggttcgacgc ggaggccgga gagctgaccg tggccgtcac ctcggacgcg gcacccgaga
    19801 ccctgcgcgc ggtccgcgcc accggcgcgc aggtgcgcac cgtcgagcac agcgcgcggc
    19861 agctggacgc ggccaaggcg cgcgtcgacc ggctcgacgc ccccgttggc gtcagcggtt
    19921 ggcacgtcga ccagcgcgcc ggcgccgtgg tcgtcgacgt ggtcgagggc aagcgcgctg
    19981 acaacgatgt ccagagcttc gtgaagcggg cccgcgaggc cggaccggtc acggtgcgtt
    20041 cggtgccgtc ggccccgcag accttcgcgg cgggcaccgt cggcggcgac ccctactaca
    20101 ccggcaacgt ccgctgctcc atcggtttct cggtgtacgg cggcttcgtc accgccgggc
    20161 actgcggacg ggccggcgcg ggggtcagcg gctgggaccg ctcgtacatc ggcacgttcc
    20221 agggctcgtc cttccccgac aacgactacg cgtgggtcag cgtgggcagc ggctggtgga
    20281 cggtgccggt cgtgctcggc tggggcacgg tctccgacca gctcgtgcgc ggctcgaacg
    20341 tggcgccggt gggcgcctcg atctgccgct ccggctccac cacgcactgg cactgcggca
    20401 ccgtcctcgc ccacaacgag acggtcaact acagcgacgg ctccgtggtg caccagctga
    20461 ccaagaccag cgtgtgcgcc gagggcggcg actccggcgg ctccttcatc agcggtgacc
    20521 aggcgcaggg cgtcacctcg ggcggctggg gcaactgctc cagcggcggg gagacctggt
    20581 tccagcccgt caacgagatc ctgaaccgct acggcctcac cctgcacacg gcctgacccg
    20641 gcgacggagg ggaggtccgc gccggtctcc ggcccggtcc tccccgttgt cggtgtccgc
    20701 aggtgctggt acgaccgcgt gacccgcgcg gctcagaggt ctccggggcc cggctccggc
    20761 gcctccaggc ccgtcgccgt cgtcagccgg cggtacgcgg cccgtgcgtg gaccaggcgg
    20821 gccagggcgg tgccgacgag ggccgcaccg agcagacacg ccagccagac cgcgtcccgc
    20881 cggccggtcc acgtgagggt gccggccggc ggtatggcga acccgttgag ggacagccag
    20941 cacaggacgg ccgtccccgg cgcggccgtg aaccgggcgc agagcccgag cacggccgcc
    21001 agcagggaga gcaccacgag ggcgagcccc ggacggcccg agcccacggt gccgttgagg
    21061 agcgccaccg cgaggagggc gccgccgaac gctcccgccc acaccagggg ggccgcgacc
    21121 ggccggggca cgggtctggc accgctgccc aggggcaccc actcgatcat gctgacggct
    21181 ccttccggtc cggacgtgtc cggccacgtc gtcggacggc cgccctctgg gcagattgtc
    21241 ccaccggaag gcagggtgcg gtgccgtccg ggtcggcacc aggccacccc gggcgaccgc
    21301 gcccggaccg cgcccgctct gcccgtccgt ccgtctagcg ctcggcctcc gcacgccccg
    21361 aggacggggc cgagcacgag gaggaggcgg gcaacggctc cggctccgtg tccgacggcg
    21421 acgccgacgg accgtgcgtc tgcgcgtcct tgccggcccc gccgcccggc acctccggtc
    21481 cgggtgtcgt cccgggcagc agccggcccg cggcccgcaa cccggcggcg aggacatggg
    21541 cccgtcccgc gacgatgggt ccgaggacgg cgaggacgag cacgtaaccg gcgatgaagg
    21601 gagcgaggcg cgcgtcgagc ccggcgcccg cggccatggc ggccaggatc agcgcgaact
    21661 ccccgcgggc caccagggtg gtggcgatct ccgcggccgg ttcggagccg tagtggtaca
    21721 cccgggcgac gcacagcccg gcgacgacgt tcatgacgac ggtcagcgcc gccgccgcgg
    21781 cgaccggacc ggcgacggag gcgaggtcgc cggggtcgat ggcgagtccg aaggcgaaga
    21841 agaagatggc cgcgaaggcg tcgcgcagcg ggtgcaccag ttcgcggatg cggggccccg
    21901 acggggtgcc ggcgaggatc aggccgacca tgaacgcgcc gatcgcgtcg gcgacgccga
    21961 gcacttcgga gacaccggcg acgagcaccg cggcgccgag gaagctgatg acgagcagtt
    22021 cgttgtcccg cgtgtggatc aggcggccca cgagccgggt gccgtagcgg gccgcggcgg
    22081 ccagcaccag caggaagccg aaggccttgc cggcctgcag gaccgtgtcg gcgacgccgt
    22141 gcgcgcccgc gatgaccggc tgcagggcgg ccaggtacag cgcgaggaag atgtcctcca
    22201 cgacgatgac accgaggatc agccgggtct ccgggcggcc gatccggccc aggtcgatga
    22261 ggatcttggt gacgatcgcg gacgaggaga tgccgagcac acccgccagc accagcgcct
    22321 cgcgcacacc ccacccgagg acgaacccga aaccgagccc ggcaccgacg ttcaggagca
    22381 gatagacgcc ccccgcggtg agcagccgtt tgccgccgct cctgaggtcg tcgaggtgga
    22441 actccaggcc caggtagaag aggagcagca ccagtccgag cgcggagagc atctcgaagt
    22501 cgtgcgcgtc ctccaccagg acgaagcccg gtgtgtgggg gccgagcagg atgcccgcga
    22561 gcatgaacag ggggatcgtc ggaagtccga tcctgccgcc gaggcgggcg aggaacgcgg
    22621 cggccacgaa ggcaccgccc atggcgagca gggtgtcagc gtgtcccacg ggtcaccccc
    22681 tgcgaccgcg cggagggtcg ggagggcttc acttgacggg gatggatgcg cattctcctt
    22741 cgtcggtcgt acgtcgtcgg gtcggacagc cggacggtcg gggaccgccc atgacgccgt
    22801 gccgtgacac cgccgcgggg cgggacgggg gacaccgcgg gtcggcagcg cgcccgggcc
    22861 gtgagcgccc ggagaccggg ccgccgcggc ggtgcaccac catgaccatc gaccgccccg
    22921 gcgctcggcg tgcgcaccgc gcacacccgg accgaaccat gcggcaacgc ccgcgaacgg
    22981 gcgggacagg gcctccctga aacgtccccc ggcccccgaa aaggcccccg gggcgcggcg
    23041 tcggtccacg gtcacacgcc gggcggcccg gcggccatcg gggacgacac ccaaatgatc
    23101 cggtggccga cacccatcga gcggccgggg cgcggggccg gtcggccggt cggccggtcg
    23161 gccggtccga ggaggatgcg ccgcggccga ctcggggatc ccggccgcgg cgcgccctgc
    23221 cgccccgggc gcgggaggac tgcgcgcggc ggggcatgcc cggcgtcttc ccccgctcca
    23281 cgtcctgata ctgcgccaac cgagtgaccg tcagggagcc gccctcccgc tcccgggttc
    23341 ccggcccctc acccggggcc gggagtgagg gccggcgccg ccgtgcggca gaacgccgtc
    23401 cgccccgccg cgggcgcggc ggggcggacg attcgcggac ggtccgtcag cacggtgtgg
    23461 ttgccatcag cttctcgaaa gaagccatgc agtccgggca gtgccgcgcc cgttcaccgt
    23521 cggatgcctc catacgttcg cggagctgct gtccgcagag tgtggccgcc gcctgtttgg
    23581 ccagcacgtg ccacaccaac gctccgcccg ccttctccgg gcccacgcac atttcgtaca
    23641 tgatcggcct cccagcctgg acgccgctga caccctcaag gagacaccgg ttggaccgtg
    23701 accagtagtg cgcggggtcc attcgggtga cggccacttc ggccgcccgt ggcggccgca
    23761 cacccgcagg gctgcaaacg atcagccaac cggccgtgtg cgggtgcgcg tgacgcgccg
    23821 tcagg
//
