LOCUS       NZ_CP116257            26458 bp    DNA     linear   CON 15-DEC-2024
DEFINITION  Streptomyces lienomycini strain DSM 41475 chromosome, complete
            genome.
ACCESSION   NZ_CP116257
VERSION     NZ_CP116257.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces lienomycini
  ORGANISM  Streptomyces lienomycini
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7863969)
  AUTHORS   Ding,W.
  TITLE     Streptomyces riduolalong sp. nov., isolated from the soil of Tibet
            exhibits against Gram-positive bacteria activity
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7863969)
  AUTHORS   Ding,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JAN-2023) School of life sciences and biotechnology,
            Shanghai Jiaotong University, 800 Dongchuan, Shanghai, Shanghai
            200240, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: GS De Novo Assembler v. August-2022
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_027947595.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 16:03:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,183
            CDSs (total)                      :: 7,093
            Genes (coding)                    :: 6,850
            CDSs (with protein)               :: 6,850
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 243
            CDSs (without protein)            :: 243
            Pseudo Genes (ambiguous residues) :: 0 of 243
            Pseudo Genes (frameshifted)       :: 141 of 243
            Pseudo Genes (incomplete)         :: 121 of 243
            Pseudo Genes (internal stop)      :: 14 of 243
            Pseudo Genes (multiple problems)  :: 26 of 243
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:34:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2614092
            Orig. end                         :: 2640550
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP116257.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26458
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="10"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26458
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26458
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16458](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16458)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    163..172
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.08"
                     /tool="antismash"
     misc_feature    complement(385..398)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     gene            complement(1931..2281)
                     /locus_tag="BJ961_RS11835"
     CDS             complement(1931..2281)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389171.1"
                     /locus_tag="BJ961_RS11835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_007389171.1"
                     /transl_table=11
                     /translation="MKWNLRWAAAKQNIWRPSELLPRFAEYGFTPSLSKVSALWSGIPV
                     TVRLDDLDKMCAALNCTVGDLMEADPVERVAPGAEQGQSQERAVGDDGPGSAGPRPVPQ
                     RGTGRPRSLPPN"
     gene            complement(2278..3546)
                     /locus_tag="BJ961_RS11840"
     CDS             complement(2278..3546)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389172.1"
                     /locus_tag="BJ961_RS11840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="site-specific integrase"
                     /protein_id="WP_007389172.1"
                     /transl_table=11
                     /translation="MRPRPHTLEFWCYWQNLRVIPVTSWIVTDSGTRVLSLVPPLIDEV
                     LDESSGVRGGDQGLVDVLSLQRRYAGGASLEDEQAFFMDTLVEYQWARDLAGLASSTLD
                     ALTKPVIEVCDHYQLVPWRLTPRHVDAYFAGPGKRQAPTIRSKLNKIDHFFAFLEQRYA
                     HEIFQQFGAMVESPIDPFNRQAHRGDFGLRVPPSARATKEFFAAWRSDLPNARKEAVAC
                     RDYVMSKMIYISGVRAAELCGMKMCDLHWESGEFGRFLVQGKGARGSGPRPREAYMFAE
                     GRALMWWYVSEVRGLFADDPEHPEAPVWPSERLPRSIEDLNMPVAPAVTPSTLRKALKR
                     ASAGHLHGPVRQLFPHLLRHACATHRYEGGMSLWEVQKLLGHEWTTTTVRYILSAQGDP
                     EVASRQSSARATQRLRVDAGSLS"
     gene            complement(3596..4219)
                     /locus_tag="BJ961_RS11845"
     CDS             complement(3596..4219)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012514.5"
                     /locus_tag="BJ961_RS11845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_381156735.1"
                     /transl_table=11
                     /translation="MRPTYREDGSWVLPGGVVEHGEHPHVTCRREITEELGLDLPLSAV
                     LAVHSFSAHHPDLQSGTHCPGEVRFVFDGGTLTPDQVEAIRLPTKELSEYAFLETRDAV
                     QRLRPVDGQIMLAAYRARLGNTATAHLADGRHILDVPALDRHDVHVRFRPLWDSPLHPG
                     PVPERLPVRQAWAWCFILDGRVVVVADPGPRGALPMLTGVRAGS"
     gene            complement(4354..6351)
                     /locus_tag="BJ961_RS11850"
     CDS             complement(4354..6351)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015579849.1"
                     /locus_tag="BJ961_RS11850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_381156731.1"
                     /transl_table=11
                     /translation="MKRFFGPVSMAEPQVSDAEQELFGGPLRYDMGWSQHEHATLDLTM
                     LSALRSMPGLVGSTLRMAWQADRRALLSVGVSEIGQGIAAAAGLLAVNAIMHALLAGTG
                     SGADRLHALLPGLLAAAIVGVVNSALSAWSTSRAGRLEPKVERIATTQYLAAAARVELE
                     AIEDPDFRRLVDIAQLGPGSARRMIGSCVAALNGLISLITTAGVLAVLHPALLPMLILI
                     AAPRGWGAMRVAQERYVSVMSWIEHVRASRLIGNLLTERTAAQEVRLHAVGAFLLSRYE
                     RMAESAEAEQERLASSKALTEWVASALSGLAMAATYGAMFWLIMAGHMSLAVAGTAVIA
                     VRTGSASLGALVMNINQLHEESLYVRDHGRFLTEAGQRTLPAGGAPVPERVKEIVLDQV
                     TYRYPDRDTAALDGVSLTLPMGLVTAVVGENGSGKSTLMKILSGMLLPASGTLRWGEAD
                     LTGLDRAQVFERVSLLTQDFQRWPVTAAMNIRLGRPDHSATDDDLKPSVDYAAAGPVIA
                     KLPDGLRSLLARMFRGAIELSGGEWQKVGLARTHWRSSTSQADGVLIVDEPTSALDPEA
                     EIEAFDRIRRLAAPNRAVVLVTHRMSGVRHADHIYVLNNGHLAEHGTHDELITARGRYA
                     AMFDAQAAQYAPTATIPHPAAPTVPEGRAT"
     gene            complement(6348..6815)
                     /locus_tag="BJ961_RS11855"
     CDS             complement(6348..6815)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006143035.1"
                     /locus_tag="BJ961_RS11855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_271321263.1"
                     /transl_table=11
                     /translation="MSESPHLLIADVAQVLLRSNGTALCVRRNPGTALAPGQLTVIGGH
                     LEADEPLDHAARREAKEETGILLSAEQQEFCGLIHHYDPGDGLDRVTAVFVAQSWTGAP
                     YNAEPNKHEGFYWVPMQRPSPDCHPYTATIFHLLTHGPCFRATNWPAGGAR"
     gene            complement(6812..7021)
                     /locus_tag="BJ961_RS11860"
     CDS             complement(6812..7021)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BJ961_RS11860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_271321264.1"
                     /transl_table=11
                     /translation="MNHATKPLRPTDPSMGYGRRLSETEAPALTAFAVTETACVIAYGP
                     RQGNVLVTARGPRIVKRMRQEGRP"
     misc_feature    complement(7244..7259)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.63"
                     /tool="antismash"
     gene            complement(7544..8767)
                     /gene="fxlM"
                     /locus_tag="BJ961_RS11865"
     CDS             complement(7544..8767)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006379288.1"
                     /locus_tag="BJ961_RS11865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_271321265.1"
                     /sec_met_domain="PCMT (E-value: 2.6e-42, bitscore: 143.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAASTAPTNPDEALAKRLIGSGHLRSQAAIDAFRTTDRHAFLPGV
                     ALESAYEEDAVPIKHNEYGEMISCISAPSIVATQLEQLGAQPGHKVLEAGAATGYNAAL
                     LGKIVSPGGQVWTVDVDQDLVAGASRHLAEAGVDNATAVMADGAAGLPEHAPYDRIIFT
                     VGAGDVPVEILDQLAPGGRLVLPMRVRGSISRSFAFERDGETWKTVSCKMATFIPLRKG
                     VCDDVYTLVPMAGEGNVRLETFSEQDVDHKALRSVLDQQQTKIYTGVKFRQGSAWEWLY
                     LYLACVLPNGLSRLPGQRPGFTPHFGWGSMAALDAGSLAYLTIREGHEKGRYWEVGVIG
                     HGEGGGDLAERVVSEIRAWDASGGNDAPEPSFRMATADSRDRLTADDARFVVDKPYSRL
                     VVDWARKG"
     gene            complement(8875..9999)
                     /locus_tag="BJ961_RS11870"
     CDS             complement(8875..9999)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016325336.1"
                     /locus_tag="BJ961_RS11870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_271321266.1"
                     /transl_table=11
                     /translation="MDVSQIAKRFPLVARPRPACPPLAERVREITDLAAAAERDGNVTS
                     ATVALNKAALIASDCSMPDLARTLCWRHAEAVLRAQPLGAQEARYALEPLVNLARLRIR
                     DGDGHGAYHLLDSLNRAVRSKTEAVIDGRTKSFQHLTTSAADHEQVCQWLWTVLLGDGT
                     RALVAAGEWDRARAHSRQHRGIGQRLFDGRQVEVLVRCLGEQPSDALTFLHASQLVEPW
                     EQSVAAALTVLCHRAADEHPVEPIDKMVQHYLALDSDPELAVFRSRVGLVVLDLSPKTQ
                     QAEAMRRLTCEAMAQADGYVARDVLAHPVCREALSYGEHRTLSAAIASAGLGQGHIPEP
                     LAQALLGAASVSADVWERHVTRRASSGSSHNLDS"
     gene            complement(10001..12091)
                     /gene="fxlM"
                     /locus_tag="BJ961_RS11875"
     CDS             complement(10001..12091)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016325335.1"
                     /locus_tag="BJ961_RS11875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_271321267.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.3e-28, bitscore:
                     99.1, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 6.2e-44, bitscore: 148.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTADEWPQRLIRFTDWSHAEATAVEYLLPVLIAQESELAQWSFLR
                     KHPWWRLRYRPAGPDSAEVLDAALGELVDAGVLASWTRGIYEPEETAFGGPAAMKIAHT
                     LFHYDSRHLLDEAARQQTVSGPQLGRRELAVLLLSVAMRAAGLDWYEQGDVWAKITAER
                     PGDEVRTPQRHRAAVHRLMTVDVSTTSRSVTQDRLAPLAEWIATFEWFGQQLADLNRQG
                     RLERGLRAVIAHHGIFHFNRLGLAAQDQHTLSTLAKEVVMGTSDNTASTQAERTPGATV
                     NGVNSDTIEAPSADRLRAQLIDHLVETGCVLTPRVEEAMRTVPRHLFVPNAPLEKAYGN
                     APVDTKFDGSGRSISCASQPDIVAMMLEQLDVQPGQKILELGAGTGFNAGLLGYLVGET
                     GHVTTIDVDEDIVAGARGGLAAADIHNVEVILGDGAVGHTPNAPYDRIEATVGAHGVPH
                     AWLDQLAPGGRLLTPLRLRGSVSRSIAFENQDGAWRSVGSQMNTFMPLRRGIADDPRLF
                     VPLDPDHTVTLVTNGDQKVDADALSDIFRQPRTEAWTDVTFRGPESAEYLELWLTCAMP
                     NGLSRMPAKNKAIEKGLVTAPYPSSTAVFEGGTLTYLTRRPYAKKAPDGATLYEFGVIG
                     HGPDAEALASDVADQIRTWDQDFRALDVGFEIKPLDSAPLAPKPGRFAFDNPLNRIVIE
                     WQ"
     misc_feature    complement(12011..12013)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12110..13369)
                     /locus_tag="BJ961_RS11880"
     CDS             complement(12110..13369)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491155.1"
                     /locus_tag="BJ961_RS11880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_271321268.1"
                     /sec_met_domain="LANC_like (E-value: 1.2e-63, bitscore:
                     213.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVRDSALATADVLAERLASPQDVRGLHHRQGWWPQSLAHGAAGV
                     ALLHIERARTGQGPWQRAHDWLACAAAEPVVGGPDSHLYYGAPALAFALHAAADRPGRY
                     ARALDTLDRYVTKAIRDRLAHAHARMDRGEMPALAEFDAIRGLSGMGGLLLHRDVHTDV
                     LREILTYLVRLTEPVRHDGEVLPGWWSHLAPSGTISPDYLEGHANNGVAHGIGGPLAVL
                     SLTARRGVTVDGHLDAITRILTWLDHWQQNGPAGPWWPYWITREQLRSGTTGPGPSRPS
                     WCYGTAGFARAQQLAALALKDPARQHAAEFALLRAMTDPGQLDATVDVSLCHGFAGLAH
                     ITQLTATDALTPGLTACLPRLLAPITDTAPGTLADSLINPPGGGDIGLLEGAAGTALAL
                     HSFHTGTPSASGWDTCFLTN"
     gene            complement(13366..16458)
                     /locus_tag="BJ961_RS11885"
     CDS             complement(13366..16458)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031312.1"
                     /locus_tag="BJ961_RS11885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_271321269.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.5e-201,
                     bitscore: 668.9, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.6e-16,
                     bitscore: 59.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.5e-24, bitscore:
                     85.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSRKDGPLYRCADAALVRAAHYSKVPLPAWPDLADDAPDGEVRW
                     QTWLRDVWSLSEAAEAIEQGSPLLAQQVQALCSVASPETRQLRRAVVSVMRYLLRMTGR
                     ATPNGLFAGVAPASFGERPGWSWGEWHQPVIRADGDWIADLIARLEAHPEVLRHLHVMA
                     NNTVFVRGDRLIVPYPPRSRRTEGSPAAEVSVRYTNAVRIAVDAAASPVPVHTLVELMR
                     TEYPDVPADRVEGLVSSLVERGVLISSLHAPSAALDALDHLVEQAKAAGAPSAADLVAD
                     LRAVRDAIAQHNQVLAPADGQRLRTALRQKMTALSTVKAQPLTLDLRMDCSLTLPPQVA
                     REAEKAATVLARLSAYPFGTPAWKDFHNRFFERYGINSLVPVRDLVDPDVGLGFPAGYR
                     DAEPEQREALTTREQRLLSLAQAAVLDGRDEISLDEDLIRTLTVGDRDAPQVPAHTELR
                     FQIRATSQEALEKGDFVLHGIAPSRGIGTTIGRSLGLLTPEDQARAAAMLEKLPVNAPG
                     SVPTQVSFTPLDRGDTNVTRVAELLPAVISLAEHRPVDERTVTLDDLAVGCDRRRLYLV
                     SLSRACLLDPMTLHALDLRGHTPPLARFLAEISRSQTAVLSIFPWASATALPYLPRVRY
                     GRAIFSPARWRLDRSELPDRRAPWKEWHKAADEWRTRRRVPDEVSLAEEDQLLPLDLSE
                     RAHLALLRAHLVTHESALLTEAESDGGWFDGRAHEVIAPMTAVRPPQWPTVPPVTADQL
                     ITREHGHLPGAAFWLLVKLYGHVDRQPEILADHLPALLGQWDEPPTWWYMRYRDPCWHL
                     RLRIAVPSEQDLALTARRVSSWANGLRRAGLLTDMQFATSYPETGRWGAGPLMSLAEDV
                     FAADSRALAVQFAQRTRPHRQVLAAANFVSLAAAFTGGTAAGMDWLITHGRIIDPRPLD
                     RTVRGQAVRLADPTDGWAALRAVPGGAAVARAWSGRDAALACYRQKLDASGGGIDPDLV
                     LDSLLHAHHIRAAGIDKDDERMCIRLAHAAAMAWTHRGDHQ"
     misc_feature    complement(15535..15537)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        complement(15700..15978)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_BJ961_RS11885_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="6.20E-19"
                     /identifier="RREFam001.1"
                     /label="BJ961_RS11885"
                     /locus_tag="BJ961_RS11885"
                     /protein_end="253"
                     /protein_start="160"
                     /score="59.5"
                     /tool="antismash"
                     /translation="VMANNTVFVRGDRLIVPYPPRSRRTEGSPAAEVSVRYTNAVRIAV
                     DAAASPVPVHTLVELMRTEYPDVPADRVEGLVSSLVERGVLISSLHAP"
     gene            complement(16542..16721)
                     /locus_tag="BJ961_RS11890"
     CDS             complement(16542..16721)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491157.1"
                     /locus_tag="BJ961_RS11890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_271321270.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 2.4e-11, bitscore:
                     42.1, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNANTIKGQAQSPAATAEGDAFDLDISVLESGDGSATVINLTDDG
                     CKPSCQGSCATNVA"
     gene            complement(16759..16890)
                     /locus_tag="BJ961_RS11895"
     CDS             complement(16759..16890)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491158.1"
                     /locus_tag="BJ961_RS11895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_011031314.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 9.2e-16, bitscore:
                     56.2, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNDEFDLDISVLESDDGSATLINLTDDGCGSTCSSPCATNVA"
     CDS_motif       complement(16825..16890)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MQNDEFDLDISVLESDDGSATL"
                     /locus_tag="BJ961_RS11895_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16759..16824)
                     /prepeptide="core"
                     /locus_tag="BJ961_RS11895_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="1.60"
                     /molecular_weight="1921.1"
                     /monoisotopic_mass="1919.8"
                     /core_sequence="INLTDDGCGSTCSSPCATNVA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MQNDEFDLDISVLESDDGSATL"
                     /leader_location="[16824:16890](-)"
                     /alternative_weights="1939.1"
                     /alternative_weights="1957.1"
                     /alternative_weights="1975.1"
     gene            complement(16998..17177)
                     /locus_tag="BJ961_RS11900"
     CDS             complement(16998..17177)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04363.1"
                     /locus_tag="BJ961_RS11900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_271321271.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 9.7e-13, bitscore:
                     46.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPRVTDQRVRTVSASAAQDPFDLDISVIESGGTVGAGIASDGGC
                     GSTCGGNACISSGS"
     CDS_motif       complement(17064..17177)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MTPRVTDQRVRTVSASAAQDPFDLDISVIESGGTVGAG"
                     /locus_tag="BJ961_RS11900_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16998..17063)
                     /prepeptide="core"
                     /locus_tag="BJ961_RS11900_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-2.20"
                     /molecular_weight="1695.8"
                     /monoisotopic_mass="1694.7"
                     /core_sequence="IASDGGCGSTCGGNACISSGS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTPRVTDQRVRTVSASAAQDPFDLDISVIESGGTVGAG"
                     /leader_location="[17063:17177](-)"
                     /alternative_weights="1713.8"
                     /alternative_weights="1731.8"
                     /alternative_weights="1749.8"
     gene            complement(17381..17848)
                     /locus_tag="BJ961_RS11905"
     CDS             complement(17381..17848)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491161.1"
                     /locus_tag="BJ961_RS11905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6082 family protein"
                     /protein_id="WP_271321272.1"
                     /transl_table=11
                     /translation="MKLTTAVLAAGAAVSLTTAVVGATRLRQDARHQAERNEVFLTGNQ
                     LDWLAQVSTSPDLAKLSAPEDLDVEEYMQLLAANRLICMLSVRDRLGFIRTGHLPWHAA
                     KLMESDACQRYWKRFGGLRAEEAEGDEQAEHFTRVLDQAAKNRPQAQRPAA"
     gene            complement(17923..18333)
                     /locus_tag="BJ961_RS11910"
     CDS             complement(17923..18333)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042672.3"
                     /locus_tag="BJ961_RS11910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6624 domain-containing protein"
                     /protein_id="WP_333782102.1"
                     /transl_table=11
                     /translation="MLADHDWPGHRLVGPDGARAAWSIALHSDDNYALQRAATTLLGRA
                     VQAGDALVQHWAHLHDRALVTSGSAQEYGTQFLLSTDGIELCPLRAPGSVDARRATVGL
                     PPLAVALNAVCRRYTPDSSADETPTVLLAGAA"
     gene            complement(18374..19612)
                     /locus_tag="BJ961_RS11915"
     CDS             complement(18374..19612)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1130: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558065.1"
                     /locus_tag="BJ961_RS11915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS256 family transposase"
                     /protein_id="WP_381161146.1"
                     /transl_table=11
                     /translation="MAAAVDDELIGQLVTRAQADGLKLTGEGGLLQQLTKRVLESALEG
                     ELTDHLGHEHGERAEGGRENYRNGHRSKTVATEVGPVGISVPRDRAGSFEPMLVKKRQR
                     RLGGIDEMVLSLSAKGLTHGEISAHLAQVYGTEVSKSTISTITDSVVAGMVEWQNRPLD
                     AVYPVVFIDCVHVKVRDGQVANRPVYMALAVTAEGTRDILGLWVGDGGEGAKYWLQVLT
                     EIKNRGVRDVLMLVCDGLTGLPDAVNTVWPATIVQTCVVHLLRNSFKYAGRQDWEKIAK
                     ALRPVYTAPTEDAATERFLEFSEEWGAKYPAIVRLWERAWAEFVPFLQFDVEIRRIVCT
                     TNAIESVNARIRKAVRARGHFPTEQAALKCVYLAVMSLDPTGTGAKRWTRRWKPALQAF
                     DITFDGRLTAAQL"
     gene            complement(19694..20059)
                     /locus_tag="BJ961_RS11920"
     CDS             complement(19694..20059)
                     /EC_number="2.7.13.3"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.5"
                     /locus_tag="BJ961_RS11920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_333782103.1"
                     /transl_table=11
                     /translation="MEAQQPLTDGTSAAVRTRSGACEIDVTLTAAAVSGMRGLVSACLR
                     LWGLTELDWRVTLTASELLTNAFQHARKEDESSVPVKVVLTRTPDGVFLCVSDPHPWPP
                     APVPAGDDDEGGRGSVR"
     gene            20233..21636
                     /locus_tag="BJ961_RS11925"
     CDS             20233..21636
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031332.1"
                     /locus_tag="BJ961_RS11925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_271321274.1"
                     /transl_table=11
                     /translation="MPRPEKQLTPDASPRDWFGHELRTWRKKRGPLTHAELGTNVQVSG
                     SLIEKIEKGTATCSKDLAERLDEVLQTGGVLTRAWGMVFGQTEKARPETESAPPRRAEV
                     PVQVHEGRILGRGSTTPPSGSPASVDRRAFLATSGLAAIAPIDLVHLVTPAAPREIPTQ
                     IRPREIRQVKSLADVIHRQDNEYGGGGAVRELARGAIMWGAFLLPVPCPEPLRPELLAS
                     VARLGIVVGASQFDAYAHDDARVSFRLAAECAEEAGEWHLRAKTYSFMARQEIWIGDPD
                     TGLTHAEKGLVRSDRLTATERAMLHTARARAFGKMHDVANTLRAVGEADAAFEHSDPVQ
                     DPPWMAYYDYAQHHGDTAHALFDLAVHADHDPGQAARRFEIAVKGHGNAFARSRAISET
                     KLASLVMAKGDDPRHAVVLGHRALDDVGKLTSCRAAEDLRELARFAGRHRSLPEASDLR
                     ERIAATVQA"
     misc_feature    20277..20291
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     misc_feature    20908..20910
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            21633..22514
                     /locus_tag="BJ961_RS11930"
     CDS             21633..22514
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018549474.1"
                     /locus_tag="BJ961_RS11930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_271321275.1"
                     /sec_met_domain="APH (E-value: 4.8e-23, bitscore: 81.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSPTPTQAVLKEACLAAGLDATNAQPIRIAENAIWRLPGGTVV
                     RIARPGQSAAATREVQVARWLATQGVPAVRALGLRQPVIASGHPVTFWQELPPHEIGTI
                     TDVVVLLKQLHALPIPDLPLGELDPFVRLVERIDAASTTSADDRLWLKGRLKDLKQQWA
                     SRPKGRPECVIHGDAWVGNVARTEAGPMLLDFERSSFGPPEWDLVSTAVKLTTTGAVSA
                     EEYAAFCETYGVDVTKWEGYEILAGARELRMVTYAAQHAASRPEWRREAQYRIDCLRGR
                     AGVPPWRWKGIM"
     misc_feature    complement(22561..22577)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 21.16"
                     /tool="antismash"
     misc_feature    complement(23230..23243)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            23467..23766
                     /locus_tag="BJ961_RS11935"
     CDS             23467..23766
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024139.5"
                     /locus_tag="BJ961_RS11935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AlpA family transcriptional regulator"
                     /protein_id="WP_263549179.1"
                     /transl_table=11
                     /translation="MHRSAIPPAPTTSSVAVRTAFLTVQDAAEYLGLSHHTLYVWRHRR
                     QGPPSFRMGPRGRVMYRVEALDAWVREQEQADSRSNLALNPLSADPQQRIRPSA"
     gene            23781..25124
                     /locus_tag="BJ961_RS11940"
     CDS             23781..25124
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017236903.1"
                     /locus_tag="BJ961_RS11940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="site-specific integrase"
                     /protein_id="WP_263549178.1"
                     /transl_table=11
                     /translation="MSTVCTPVEKEIPLAGYIEDRWIKKKKDPVTGKRERTARYGKGKR
                     YKAAGIPGVRDRSFDTLEDAKAWLRRSSTDQERGEFVDPRDGSLTVAEYVERYWMPGVR
                     GEAKTRKGIDERIRLHVIPHLGDVSLNEVSAAELRAYIVRLESSCSPQYARSILSTLSS
                     VLETAVDDKRLARNPMRSKSVRWPKLPDERREAWPEALARSVRDEISQRHRIAVILGLG
                     CGLRQGEVFGLSMEDVDHARGVLHVRRQVQIVNGRKYFTLPKGGKTRVADMPRSVADEL
                     VKHARAYPGDKVELPWGGPESDRERKKFGLVLTTKYGNAIAANTWNTEIWKPALARAGV
                     IPPRVKGAKPWQWQAAPKDGFHVLRHTYASLVLEAGESVVTLAKWLGHSSPTITLDHYA
                     HFMPEAGKKGRRAIDSLLGERAEESSGPNSPDSPPGPILSGDATVRRA"
     misc_feature    25892..25907
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.12"
                     /tool="antismash"
ORIGIN
        1 ggtcggtgcc gttgagggcg tggagggtga ccagggccag ggcgaagcgg atggcgggcc
       61 ggtcggtgat gtcgaggagt ccggcgaggc ggtcaggggg cagcgttgtg ggcgggggtt
      121 cgttgcgggt gacgctcagg ccgcgggtgg ggtcggtgaa tacgattttt gcctgtttca
      181 gtgcgcggaa gatcgagcgc agggcgacgg cgcgttcgtg agcgcggtcg cccttgactg
      241 cggtgacggc ggcgtggacg tcgtcggcgg tgacttgccg gagggtctgg tagcggccgg
      301 tccagtcggc aagcggtgcc cggaggtagg agaggtatcg gcgcagggtg tgccactcgg
      361 tgggcggccg gtcggagtgg ctgcgcaacc ggcgtgccca ggaggcgagc tcatcggcga
      421 tccggggcgg atagccggca atgacctgtt ccacgaaggc ttcgacactg cttatggcgg
      481 gccggggctg cgggagaagc aggccgcgtt cggccaggaa ggcgttcagc gcacgggggc
      541 ggcaactgct tccgcggccg gtggcggcgc tgatcgcgcg cagatcgtat tcggcgaaag
      601 gatcatgggt gccgagccag gtggccgcga ttcgcaggac gtgggcggcg gccttgcggg
      661 catggtttgt ccaggcgtgt gcccgggcgt gggcgtcgaa ggtggccagc agccggacgg
      721 cctccggctg cggctcggga agggtggccc tgcgcagagc ggaccagtcg cgttcagcgg
      781 ggaacagttt ctgctgcccg tacggcacga caccgggcgt gatcacctcg ctcgggtggc
      841 tctgcgcgct cgtcttggcg cgcttgcgcc cgggtgggca gaggttggtt cgcgcggcgt
      901 gccggtccaa cgactcctcg gtgaggcgta gctgccgcca tgacacgtgg tcgtatgcgg
      961 ggccgaggag ggcgcggtgg cgcaaacagc cgtggcacca accctcccgc aacggcaggg
     1021 gacccccgcc gcaacgcaca cagtctccga ccgggcgagc acgagcgccc cagatgtagc
     1081 agccccggca gagccccttg tgcccgcagc cccacgcctg gcactgcggg caacagattg
     1141 gcgcatcggc acgggcccgg tgacgctcgg ccgtctgcga cgcgtacgcg tcgccgcctg
     1201 tagccagtag ccccgcacgg tcgaggactg cggtcacgat gggccgggat ccgggcagcg
     1261 ccctgatcag gcggccgtcg atcggccagc ccccggccgc acggctggcc gccagagcca
     1321 gacgcagcac ccgcagcgcc agactgcgcg agcgcgccgc acacgcgtga ccgtctgtat
     1381 aggcgttcag tacctccatc acccggagta actccgggag ttcatcctcg gggcggtcga
     1441 cgatcgcggc ggcgtgatcg tggcgcatcc ggtacggcgc cggggacagg gccagttgcc
     1501 cggacaaggt gggtgggcag atccgcggat cgtcgcgcac cgggtcaggg cgctgcgcac
     1561 gggcccaggc gggcgggtgg tagcggccgt cactgcgctg ccggtacgcg ccgaacggtg
     1621 cggccgtcag cgtgacgccc ggcacgatca gggcgagctg cgtcacgacc tgcagcttca
     1681 cggccgcagc ggggtcgtag taccagtcgg cgtcgtggtc gatgatgacc aggacgcatg
     1741 cgcggcagaa tccgtcgatg ttgacccgcc agtcgcgtcc gcagcggcgg catacggctg
     1801 cgggattgtg ccgcttcgag cgccactggt gacagggaga gcagtacggc ggctgcgcca
     1861 gccgtcccca cccgttgcag cccacgcact cgtccgtccg cggcttcggc ttgcccatct
     1921 acgaaaccgc tcagttcggc ggcagtgaac gaggccgtcc cgtaccgcgc tgcggcaccg
     1981 ggcgaggtcc tgcgctcccc gggccgtcgt ccccgaccgc ccgctcctgc gactgcccct
     2041 gctccgcgcc gggtgccacc cgctcgacag gatcagcctc catcaggtcg ccgaccgtgc
     2101 agttcagtgc tgcgcacatc ttgtcgaggt catccaggcg cacggtgacc gggatgccgg
     2161 accacagtgc cgacactttc gacagtgacg gcgtgaaccc gtactccgcg aaccgcggca
     2221 gtagctcgct gggccgccag atgttctgct tggcggcggc ccaccgcaga ttccacttca
     2281 cgacagactc cccgcgtcga ccctcaagcg ttgcgtggcc cgcgccgacg actgccggct
     2341 ggcgacctcc gggtcgccct gggcagacaa aatgtagcga accgttgtcg tggtccactc
     2401 gtgccccagc aacttctgca cctcccacag gctcatccct ccctcgtagc ggtgcgtggc
     2461 gcacgcgtgc cgcagcagat gcgggaacaa ctgccgtacc gggccgtgca ggtggccggc
     2521 cgaggcccgc ttcaacgcct tgcgcagcgt ggagggtgtc accgccggcg ccaccggcat
     2581 attcagatcc tcgatgctcc tgggcaggcg ctcggagggc cacacaggcg cctcgggatg
     2641 ttcgggatcg tccgcgaaca gaccgcggac ctcggagacg taccaccaca tcagtgcccg
     2701 cccctcggcg aacatgtacg cctcccgcgg tcttggcccc gacccgcgag cacccttgcc
     2761 ctgcaccagg aaccgcccga actccccgga ctcccagtgg agatcgcaca tcttcatgcc
     2821 gcacagctcg gccgcccgca cccccgagat atagatcatt ttcgacatca cgtaatcgcg
     2881 gcaggccacc gcctccttgc gggcgttcgg cagatccgac cgccatgcgg cgaagaactc
     2941 ttttgtcgcc cgcgccgatg gcggcacccg cagcccgaag tccccgcgat gtgcctgccg
     3001 gttgaacgga tcgatcgggg actcgaccat cgccccgaac tgctggaaga tctcatgagc
     3061 gtagcgctgc tccaggaacg cgaagaagtg gtcgatcttg ttgagcttgg accggatcgt
     3121 cggcgcctgc cgcttgcccg gccccgcgaa gtacgcgtcg acatgccgcg gggtcagccg
     3181 ccacggcacc aactggtagt ggtcgcagac ctcgatgacc ggcttcgtca gcgcgtccag
     3241 cgtcgaggag gcaagccccg ccaagtcacg tgcccactgg tattccacca gcgtgtccat
     3301 gaagaatgcc tgctcgtcct ccagcgaggc gccaccggcg taccggcgct gcagggagag
     3361 cacgtcgacc aggccctgat ccccgccccg cacgcccgaa gactcatcga gcacctcgtc
     3421 aatgagcggc gggaccaggg acagcacgcg agtcccggaa tccgtcacga tccacgaggt
     3481 tacaggaatt actctgagat tctgccagta gcaccagaat tccagggtgt gagggcgcgg
     3541 cctcatcgca ctcccctgac ctgccgacat ggcgcaacgg tccgccgccg accgttcagg
     3601 aacccgcgcg cactccagtt agcatcggca gcgcgccccg cgggccgggg tcggcaacga
     3661 cgacgacccg gccgtcgagg atgaagcacc acgcccaggc ttgccgcacg ggcagccgct
     3721 cgggcacggg accggggtgg agcgggctgt cccacaaggg ccggaagcgg acgtgaacgt
     3781 cgtgccggtc cagggccggg acgtcaagga tgtgccggcc gtcggcgagg tgcgcggtgg
     3841 cggtgttgcc gagccgggca cggtaggcgg cgagcatgat ctgcccgtcc acggggcgca
     3901 gccgctggac cgcgtcccgg gtctccagga aggcgtactc ggacagctcc ttggtcggca
     3961 ggcgaatcgc ctccacctgg tcgggggtga gggttccccc gtcgaagacg aaccggacct
     4021 ctccagggca gtgcgtgccg gattgcaggt cggggtggtg agcggagaag gagtggacgg
     4081 cgagcacggc cgacagcggc aggtccaggc ccagttcctc ggtgatctcg cgccgacagg
     4141 tgacgtgagg gtgttcaccg tgttcgacga cacctccggg cagcacccac gagccgtcct
     4201 cgcgataggt ggggcgcacc agcagaacct gtccaacctc gttggtgatg acagcggcgg
     4261 ccccgagcca cgcggcatgc cgggacgcgg cgtactgcgc tggcgacgga acggcacgcg
     4321 gtgtgtcgtg atccgaaggg gagacgggag aggtcacgta gctctgcctt ccgggacggt
     4381 gggcgcggcg gggtggggga tggtcgcggt cggggcgtac tgggcggctt gggcgtcgaa
     4441 catggcggcg tatcggccgc gggcggtgat gagttcgtcg tgggtgccgt gctcggcgag
     4501 gtgcccgttg ttgaggacgt agatgtggtc ggcgtggcgg acgccggaca tgcggtgggt
     4561 gacgaggacg acggcccggt tcggggcagc gaggcggcgg atgcggtcga aggcttcgat
     4621 ctcggcttcg ggatcgaggg cggaggtcgg ctcgtccacg atgaggacgc cgtctgcctg
     4681 tgatgttgag ctacgccagt gggtgcgggc caggccgact ttctgccatt cgccgccgga
     4741 cagttcgatg gcgccacgga acatgcgagc cagcaggctg cgcagtccgt cggggagttt
     4801 ggcgatgacg gggccggcgg cggcgtagtc gaccgagggc ttcaggtcgt cgtcggttgc
     4861 cgagtggtcg gggcggccga ggcggatgtt catcgcggcg gtcacgggcc agcgctggaa
     4921 gtcctgggtg agcagggaga cacgctcgaa gacctgagcc cggtcgaggc cggtgagatc
     4981 cgcctcgccc cagcgcagcg tgccggaggc cggcaacagc atgccggaga gaatcttcat
     5041 caaggtgctc ttgccggaac cgttctcgcc caccaccgcg gtcaccaagc ccatcggcaa
     5101 ggtcagggag actccgtcca gggcggcggt gtcccggtcg gggtagcggt aggtgacctg
     5161 gtccagaacg atctccttga cgcgttccgg tacgggcgcc ccgccagcgg gcagtgtccg
     5221 ctggccggcc tcggtgagga agcggccgtg gtcgcggacg tagaggctct cctcgtggag
     5281 ctggttgatg ttcatgacca gcgcgcccag gctcgccgag ccggtccgta cggcgatgac
     5341 ggcggtcccg gcgacggcga ggctcatgtg cccggccatg atcagccaga acatggcgcc
     5401 gtaggtcgcg gccatggcca ggccggacag tgcggaggcg acccattcgg tgagggcctt
     5461 gctggaggcg aggcgctctt gttcggcctc ggcgctctcg gccatgcgct cgtagcggct
     5521 gaggaggaag gcaccgaccg cgtggagacg gacctcctgc gcggcggtgc gttcggtgag
     5581 caggttgccg atcaggcggc tggcccgtac gtgctcgatc cagctcatca ccgacacgta
     5641 ccgttcctgg gccacgcgca tggcgcccca gccgcgcggg gcggcgatga ggatcagcat
     5701 gggcagcagc gcggggtgca acacggcgag aacgccggcg gtggtgatca gggaaatgag
     5761 gccgttcagc gccgcgacgc aggagccgat catgcggcga gcggatccgg ggccgagctg
     5821 ggcgatgtcc acgagccgcc ggaagtcggg atcctcgatg gcttccagtt caacgcgggc
     5881 tgcggcggcc aggtactggg tggtggcgat ccgttccacc ttgggttcca gccgcccggc
     5941 tcgggaagtg gaccaggccg acaaggcaga gttgacgacg ccgacaatgg ccgcagccag
     6001 gagaccgggc agcagggcgt gcagccggtc ggcgccgctg ccggtgccgg cgagcagcgc
     6061 gtgcatgatg gcgttgacgg caagtaggcc ggcggctgcg gcaatgccct ggccgatctc
     6121 gctgaccccg accgagagca gggcacgccg gtcggcctgc cacgccatgc gcagagtgga
     6181 gccgacgagc ccgggcatgg agcgaagcgc cgacagcatg gtcaggtcca aggtcgcgtg
     6241 ctcgtgctgg gaccagccca tgtcgtagcg caggggcccg ccgaacaact cctgttcggc
     6301 gtcggagacc tgcggttcgg ccatcgagac cggcccgaag aacctcttca ccgggcgcct
     6361 cccgcaggcc agttggtagc ccggaagcac gggccgtggg tgagcaggtg gaagatcgtg
     6421 gcggtgtagg ggtggcagtc cggcgacggt ctttgcatcg gcacccagta gaacccttca
     6481 tgcttgtttg gctcggcgtt gtacggcgca cccgtccagg actgcgcgac gaacacggcg
     6541 gtgacccggt ccagtccgtc accggggtcg tagtggtgga tgaggccgca gaactcctgc
     6601 tgctccgcgc tgagcaggat gcccgtctcc tccttcgcct cgcgccgcgc ggcatgatcg
     6661 agtggttcgt cggcctccag gtggccgcct atgacggtga gctgtcccgg tgcgagcgcg
     6721 gtgcccggat tgcggcgcac gcacagggcg gtgccgttgg accggagcag gacctgggcg
     6781 acgtcggcga tgagcaggtg aggcgactcg ctcacggacg gccctcctgc cgcatgcgtt
     6841 tcacgatgcg cgggccccgc gcagtcacga gcacattgcc ttgccgggga ccgtaggcga
     6901 tgacgcacgc ggtctccgtg acggcgaacg cggtcaacgc cggggcctcc gtctcggaca
     6961 aacgccggcc gtaccccatg ctcggatcgg tcggcctcag cggcttggtg gcgtgattca
     7021 tgcctgatac ctcgtatcca gccgcgacct acgggtggac cgcgttgcgg tcgacggcgg
     7081 agtgcgaagg ggcgcccgac gagccggtcg tgttttcgaa cacgggataa acgagggcag
     7141 gaaggcgtac ggcattcatg ggggctcctc gggagagatg cggactagtg atcggataac
     7201 gggcgccctt gtgtcgccgt aacgggtgga gacgggcgaa atctagaacc tgaattcgaa
     7261 tacagggccc actccttctg tggccgagcg ggacgggctg tgatgccgtg ttcgatcact
     7321 catgtgggtt gcggtacctc cttcagggga ttgcctgaag ccgccctgtc gtatcggaga
     7381 agtcgctgca gctcggcttc gccgagggcg acggacccgc tcagagaccg ctggtacctg
     7441 cgggcgcgac ggtcagcccg gtgagatggt tgatgcgctc ctgaagcggg agcgcgtgtg
     7501 gcgggtcaag gggatgcggc tggctatcgc ggggatcatc ggctcagccc ttgcgcgccc
     7561 agtcgacgac cagtcggctg tagggcttgt cgacgacgaa gcgggcgtcg tccgccgtca
     7621 gccggtcgcg cgagtcggcg gtggccattc ggaagctcgg ctcgggggcg tcattgccgc
     7681 cgctggcgtc ccaggcgcgg atctcgctca cgacgcgctc ggcgaggtcg ccgccaccct
     7741 cgccgtggcc gatcacgccg acctcccagt accggccctt ctcgtgcccc tcgcggatgg
     7801 tcaagtacgc gagcgatccg gcgtcgaggg ctgccatgga gccccacccg aagtgcgggg
     7861 tgaacccggg gcgctggccc ggcaggcgtg agaggccgtt gggcagcacg caggccaggt
     7921 acaggtacag ccactcccag gcggagccct ggcggaactt caccccggtg tagatcttgg
     7981 tctgctgctg gtcgaggacg gagcgcaggg ctttgtggtc gacgtcctgc tcgctgaacg
     8041 tctccaggcg cacgttgccc tcgccggcca tcggcacgag agtgtagacg tcgtcgcaga
     8101 cgcccttgcg cagcgggatg aaggtggcca tcttgcagga gacggtcttc cacgtctccc
     8161 cgtcgcgttc gaaggcgaag gagcgggaga tgctgccgcg gacgcgcatc ggcaggacca
     8221 ggcgcccacc gggggcgagc tgatcaagga tctccacggg gacgtcgccg gcgccgacgg
     8281 tgaagatgat ccggtcgtag ggggcgtgct caggcagccc ggctgcgccg tcggccatga
     8341 ccgcggtggc gttgtcgacg ccggcctcgg cgaggtgccg gctcgcgccg gcgacgaggt
     8401 cctggtcgac gtcgacggtc cacacctgcc cgcctgggga gacgatcttg ccgaggaggg
     8461 cggcgttgta gccggtggcg gctccggctt ccaggacctt gtgaccgggc tgggcgccga
     8521 gctgttcgag ctgggtggcg acgatggacg gagcggagat gcaggagatc atctccccgt
     8581 actcgttgtg cttgatcggg accgcgtcct cctcgtacgc gctctccagg gcgacgccgg
     8641 gcaggaaggc gtgccggtcg gtggtgcgga aggcgtcgat ggccgcctgg ctgcgcaggt
     8701 ggccgctgcc gatgagccgc ttggccaggg cctcgtccgg gttggtgggg gcggtactgg
     8761 ctgccacggt gatctccatt cgggaggcta gggtcccagg gtcggacctg cgggtaggca
     8821 cttcagctcc ttcggtgtgc aggcgacgta acgccaaggg gctcgccacc gcggtcaaga
     8881 gtcgaggttg tgcgacgagc cggagctggc tcgacgggtg acgtggcgct cccagacatc
     8941 cgccgagacg gacgcagcac ccagcagggc ctgtgccagg ggttcgggga tgtgcccctg
     9001 accgaggccg gctgaggcga tggcggcgga aagcgtacgg tgctcgccgt agctcagcgc
     9061 ttcgcggcac acagggtggg ccaggacgtc ccgtgcgacg tacccgtctg cctgcgccat
     9121 cgcttcgcaa gtgagacggc gcattgcttc ggcctgttgg gtctttgggg agaggtcgag
     9181 cacgactagc cccacacggg agcggaagac cgcaagttcg gggtccgagt cgagggccaa
     9241 gtagtgctgc accatcttgt cgatcggctc gaccgggtgc tcgtcggctg ccctgtggca
     9301 gaggacggtg agcgctgccg cgacggattg ctcccatggc tccaccagtt ggctcgcgtg
     9361 caggaacgtc agcgcatcgc tgggctgctc gccgaggcag cggacgagca cttctacttg
     9421 acgcccgtcg aagaggcgct ggcctatgcc ccggtgctgc ctgctgtgcg cccgtgcgcg
     9481 gtcccattcg cctgctgcga cgagggcacg ggttccgtcg ccgaggagga cggtccacag
     9541 ccattggcac acctgttcat ggtcggctgc cgacgtcgtg aggtgctgga aggacttggt
     9601 gcggccgtcg atgaccgctt ccgtcttcga tctgactgct cggttcaggg aatcgagcag
     9661 gtggtatgcg ccgtgcccgt cgccgtcgcg gatgcgcagt cgggccaggt tgaccagggg
     9721 ttccagggcg taccgggctt cctgcgcgcc caggggctgg gcgcgcagga cggcctcggc
     9781 gtgacgccag cacagagtgc gcgccaggtc cggcatgctg cagtcgctcg cgatcagcgc
     9841 cgccttgttc agggcgacgg tcgcggaggt cacgttgccg tcgcgctcgg cggcggctgc
     9901 gaggtcggtg atctcgcgga cccgttcagc gaggggcggg cacgctggac gtggacgggc
     9961 aacgagcggg aaccgcttcg ctatctggct gacgtccatg tcactgccat tcgatgacga
    10021 tgcggttcag cgggttgtcg aaggcgaagc ggccgggctt cggcgcgagc ggggccgagt
    10081 cgagcggctt gatctcgaaa ccgacgtcga gcgctcggaa gtcctggtcc caggtgcgga
    10141 tctggtccgc gacgtccgag gcgagggctt cggcgtcggg gccgtggccg atcacaccga
    10201 actcgtacag ggtggcgccg tcgggggcct tcttcgcgta cgggcgccgg gtgaggtagg
    10261 tgagggtgcc gccttcgaag accgcggtcg aggacgggta gggcgcggtg accagcccct
    10321 tctcgatggc cttgttcttg gcgggcatcc ggctcaggcc gttgggcatg gcgcaggtga
    10381 gccacagctc caggtattcc gccgactccg ggccgcggaa ggtgacgtcc gtccacgcct
    10441 cggtgcgcgg ctggcggaag atgtcgctca aggcgtccgc atcgaccttc tggtctccgt
    10501 tggtgacgag ggtgacggtg tggtcggggt ccagggggac gaagaggcgc gggtcgtcgg
    10561 cgatgccccg gcgcagcggc atgaacgtgt tcatctggct gccgacgctg cgccaggctc
    10621 cgtcctggtt ctcgaaggcg atcgagcggg agacgctgcc gcgcaggcgc agcggggtga
    10681 ggagccgtcc gccaggggcg agctggtcga gccaggcgtg cgggacgccg tgggcgccga
    10741 cggtggcttc gatgcggtcg tacggcgcgt tgggggtatg gccgactgct ccgtctccga
    10801 ggatcacttc cacgttgtgg atgtcggcgg cggccaggcc gccgcgcgct ccggccacga
    10861 tgtcctcgtc cacgtcgatc gtagtgacgt gtcccgtctc gccgacgagg tagcccagga
    10921 gtccggcgtt gaagccggtg ccggccccca gctccaggat cttctggccg ggctggacgt
    10981 cgagctgttc cagcatcatg gcgacgatgt cgggctggga ggcgcagctg atggagcggc
    11041 ccgatccgtc gaacttcgtg tccacgggtg cgttcccgta cgccttctcc agcggggcgt
    11101 tcgggacgaa gaggtgacgg ggcacggtcc gcatggcctc ctccacgcgg ggcgtgagca
    11161 cgcacccggt ctcgaccagg tggtcgatca gctgggcgcg caggcggtcg gcggaagggg
    11221 cttcgatggt gtcactgttc accccgttga ccgtagcgcc cggtgtcctc tcagcttggg
    11281 tggacgcggt gttgtcgctc gttcccatga ctacctcttt cgcgagtgtt gacaaggtgt
    11341 gctggtcctg ggcggcaagg cccaggcggt tgaagtggaa gatgccgtgg tgggcgatta
    11401 cggcccgtag ccctcgttcc aggcggccct ggcggttgag gtcggcgagc tgctggccga
    11461 accactcgaa ggtggctatc cactcggcca gcggcgcgag tcggtcctgg gtgacgctgc
    11521 ggctggtggt gctgacgtcg acggtcatca accggtggac ggcggcccgg tgccgttgcg
    11581 gagtgcggac ctcgtcgccg gggcgctcgg ccgtgatctt cgcccaaacg tcgccctgct
    11641 cgtaccagtc gaggcccgcc gctcgcatcg ccacgctgag caggaggacc gccagctcgc
    11701 ggcggccgag ctgggggccg ctcactgtct gctggcgggc cgcctcgtcc agcagatgac
    11761 ggctgtcgta gtggaacagg gtgtgcgcga tcttcatcgc ggcggggccg ccgaaggccg
    11821 tttcttccgg ttcgtagatg cctcgcgtcc aggaggcgag gacgccggcg tcgaccagct
    11881 cgcccagggc agcgtcgagg acctctgccg agtccgggcc cgcgggccgg taccgcaacc
    11941 gccaccaggg gtgcttccgc aggaaggacc actgggccag ttccgactcc tgggcgatca
    12001 ataccgggag taagtactcc acggcggtgg cctccgcgtg actccagtcg gtgaaccgga
    12061 tgaggcgttg cggccattcg tccgcagtca tgttccctct tctcgtcgtc tagttggtca
    12121 ggaagcaggt gtcccacccg gacgcggacg gcgttccggt gtggaaggag tgcagggcga
    12181 gtgcggtgcc ggcggcacct tcgaggagcc cgatgtcgcc gccgccggga gggttgatca
    12241 gggagtccgc cagggtgccc ggagcggtgt cggtgatcgg ggccaggagc cggggcaggc
    12301 atgcggtgag gccgggtgtg agggcgtcgg tggcagtgag ttgcgtgatg tgcgccaggc
    12361 cggcgaagcc gtggcacagg gagacatcca cggtggcgtc gagttggccg gggtcggtca
    12421 tggcgcgcag gagggcgaat tcggcggcgt gttggcgcgc cgggtccttg agggcgaggg
    12481 cggcgagctg ctgggcgcgg gcgaatccgg cggtgccgta gcaccaggac ggccgggagg
    12541 ggccgggccc ggtcgtgccg gatcgtagct gctcgcgggt gatccagtac ggccaccacg
    12601 gtccggcggg gccgttctgc tgccagtggt cgagccaggt caggatgcgg gtgatcgcgt
    12661 cgaggtggcc gtcgacggtg acgccgcggc gggccgtaag ggagagcacg gcgagggggc
    12721 cgccgatgcc gtgggcgacg ccgttgttgg cgtgcccttc cagatagtcc ggggagatcg
    12781 tgccggaggg ggcgaggtgg ctccaccagc cgggcagaac ttccccgtcg tgcctgaccg
    12841 gctcggtcag gcggaccagg taggtcagga tctcgcggag gacgtcggtg tggacgtcgc
    12901 ggtgcagcag gagcccgccc attccactca ggccgcggat cgcgtcgaac tcggccagcg
    12961 cgggcatctc gccgcggtcc atgcgtgcgt gggcatgggc gagccggtcc cggatggcct
    13021 tcgtgacgta ccggtcgagg gtgtccaggg cgcgggcgta gcgtccgggg cggtcggcag
    13081 cggcgtgcag ggcgaaggcg agcgcgggcg ccccgtagta gaggtggctg tccgggccgc
    13141 cgacgacggg ttcggctgcg gcgcaggcga gccagtcgtg ggcgcgctgc cacggcccct
    13201 ggccggtgcg ggcccgctcg atgtgcagca gcgcgacacc ggccgcgccg tgcgcaagcg
    13261 actgcggcca ccaaccctgg cggtggtgca gcccccgtac gtcctgcggt gaggcgagtc
    13321 gctcggcgag gacgtcggcg gtggccagtg cgctgtcacg cacgttcatt ggtgatctcc
    13381 tcggtgagtc caggccattg cggcggcgtg ggccagccgt atgcacatcc gctcgtcgtc
    13441 cttgtcgatg ccggcggcgc ggatgtggtg ggcgtgcagc agcgagtcga gaacaaggtc
    13501 cgggtcgatg ccaccaccgg acgcgtccag cttctgccgg tagcaagcca gggccgcgtc
    13561 gcgcccgctc caggctctgg cgacggcggc gccgccgggg acggcacgca gggccgccca
    13621 gccgtcggtc ggatcggcca gacgtaccgc ctgaccacgc acggtccggt ccaagggacg
    13681 cgggtcgatg atccggccgt gggtgatcag ccagtccatg ccggccgcgg tgccgccggt
    13741 gaaggcggca gcgagggaca cgaagttcgc tgcggcaagg acctgtcggt gcggacgggt
    13801 cctctgggcg aactggacgg ccagcgctcg ggaatcggct gcgaagacgt cctcggccag
    13861 actcatcaac ggccctgcac cccaccgacc agtctccggg taagaggtcg cgaactgcat
    13921 gtcggtgagg agcccggcac ggcgcaagcc gttcgcccac gaactcacgc gccgcgcggt
    13981 gagggccaag tcctgctcgc tggggaccgc gatgcgcaac cgcaggtgcc agcaagggtc
    14041 gcggtagcgc atgtaccacc aggtcggcgg ctcatcccac tggccgagca gcgcgggaag
    14101 atggtcggca aggatctcgg gctgccggtc gacgtgcccg tacagcttga ccagcagcca
    14161 gaaggcggcg cccggaagat gaccgtgctc gcgcgtgatg agttggtcgg cggtcacggg
    14221 cgggacagtc ggccactggg gcggacgcac ggccgtcatc ggggcgatga cctcgtgggc
    14281 ccgtccgtcg aaccagcctc cgtcggattc cgcttccgtc aagagcgccg attcgtgggt
    14341 gaccaggtgg gcgcgcagca gcgcgaggtg cgcacgttcg gagaggtcca gcggcaggag
    14401 ctggtcctct tcagccagcg agacttcgtc cgggacccgg cggcgtgtgc gccactcgtc
    14461 ggccgccttg tgccactcct tccagggggc gcggcggtcg ggcagctccg accggtccag
    14521 tcgccacctc gccggcgaga agatcgcgcg cccgtagcgc acgcgcggca ggtacggcag
    14581 ggcggtggcg gacgcccagg ggaagatgct caggacggcg gtctgggagc ggctgatctc
    14641 ggcgaggaag cgtgcgagcg gcggcgtgtg gcctcgcagg tccagcgcgt gcagggtcat
    14701 ggggtccagc aggcacgcgc gcgagaggga gacgaggtag agcctgcggc ggtcgcagcc
    14761 cacggcgagg tcgtcgagcg tgacggtgcg ctcgtccacc ggacggtgct ccgccaggct
    14821 aatgacggcc ggcaggagtt cggcgacgcg ggtgacgttg gtgtcgcccc ggtcgagtgg
    14881 agtgaaggag acctgcgtgg gcaccgagcc gggcgcgttg accggtagct tctccagcat
    14941 ggcggcggcg cgagcctgat cttctggtgt gagcaagccc aggctgcggc cgatcgtggt
    15001 gccgatcccg cgggaggggg cgatgccgtg gaggacgaag tctccctttt ctagggcctc
    15061 ttgtgatgtg gcgcggattt ggaagcgcag ctccgtgtgg gccggtacct gcggggcgtc
    15121 tcggtctccg actgtcagtg tgcggatcag gtcctcgtcc aggctgattt cgtcgcggcc
    15181 atcgaggaca gccgcctggg cgagggaaag caaccgctgt tcgcgggtgg tcagggcctc
    15241 gcgctgctca ggttccgcgt cgcggtatcc ggccgggaag ccgaggccga cgtccgggtc
    15301 caccaggtcc cggaccggga cgagcgagtt gatgccgtac cgctcgaaga accggttgtg
    15361 gaagtccttc cacgccggag tgccaaaggg gtacgcactc agccgggcca gcaccgtggc
    15421 cgccttctca gcctcgcggg caacctgtgg gggcagagtg agagagcagt ccatgcgcag
    15481 gtccagcgtg agcggctggg ccttgacggt gctcaaggcg gtcatcttct gacgtaaggc
    15541 agtacgcagg cgctgtccgt ccgccggagc caaaacctgg ttgtgctggg cgatggcgtc
    15601 gcggactgcc cgcaggtcgg ccacgaggtc cgcagctgac ggcgcgccgg cggccttggc
    15661 ctgctcgacc aggtggtcca gggcatcgag ggcggcagag ggcgcgtgca ggctgctgat
    15721 gagcacaccg cgctcgacca ggctgctgac gagcccttcc acccggtcag cgggaacgtc
    15781 ggggtactcg gtcctcatca gttccacgag ggtatggacg gggacgggcg aggcggcggc
    15841 atcgacggcg atacgtacgg cgttggtgta ccggacggac acttcggccg ccgggctgcc
    15901 ttcggtgcgg cgtgagcggg gcgggtaggg cacgatcagg cgatcgcccc gtacgaaaac
    15961 ggtgttgttg gccatcacat gcaggtgccg caggacttca gggtgtgctt ccaggcgggc
    16021 gatcaggtcc gcgatccagt cgccatcggc gcggatgacg ggttggtgcc actcgcccca
    16081 ggaccatcct ggccgttccc cgaatgaggc gggcgcgacg ccggcgaaca gcccattcgg
    16141 ggtcgctcgg cccgtcatac gcagcaggta ccgcatgacc gacaccactg cgcggcgcaa
    16201 ctgacgggtc tcggggctgg ccaccgagca cagggcctga acctgctgcg cgagcagagg
    16261 actgccctgc tcgatggctt cggcggcctc ggacagcgac cagacgtcgc gcagccacgt
    16321 ctgccaccgc acctcaccat ccggggcgtc gtcggcgagg tccggccacg cgggaagcgg
    16381 caccttcgag taatgggcgg cgcgcaccag cgcagcgtcc gcgcaccggt acagcgggcc
    16441 gtccttccgg gaatccatgc accctccctg gttgtggcgc gttggggtgc cagcccgcgc
    16501 ggcacaaggc cgcacgggct ggcagattgg cgcgctcggc gtcaggccac gttggtggcg
    16561 caggacccct ggcagctcgg cttgcagccg tcgtccgtca ggttgatcac cgtggcggag
    16621 ccgtcgccgg actccaggac gctgatgtcc aggtcgaacg catcaccctc cgccgtggcg
    16681 gccggggact gcgcctggcc cttgatcgtg ttcgcgttca tgcaggtttc tccctactcg
    16741 tcgtgcggtg gaaaatgatc aggccacgtt ggtggcgcac gggctggagc aggtgctgcc
    16801 gcagccgtcg tcggtgaggt tgatcagcgt ggcggagccg tcgtcggact ccaggacgct
    16861 gatgtcgagg tcgaattcgt cgttctgcat gtgctgattc ctccgttgcc gtgcgcggct
    16921 ccgattgagc cgcgagggga cgtgccgcgt tggcggcgcc ggcgcgacat gggcgtcgtg
    16981 ccggtggtct ggtgcggtca ggagccgctg gagatgcagg cgttgccacc gcaggtcgag
    17041 ccgcagccgc cgtcggaggc gatacccgcc ccgaccgtgc cacccgattc gatgacgctg
    17101 atgtcgaggt cgaacgggtc ctgcgcggca gaggccgaga cggtcctcac gcgctggtcg
    17161 gtcaccctgg gagtcacggg aaccctcctg gtcgatgtgg tggaactctt cgattcggtg
    17221 tgttgctgta cggctggctc tgtccgatag acggcagtgg tgtgccctgc gccgctcggg
    17281 cctcctcggc tacctcgcca gacacgagaa ctgctgtccg gctgaagaat tggggacgga
    17341 cacggagccc gaagaagggt gacgggaccg agatacgccg tcaggcagct gggcgctgcg
    17401 cctgcgggcg attcttggcg gcctggtcca gcacccgggt gaagtgctcg gcctgctcat
    17461 cgccctcggc ctcctcggca cggaggccgc cgaaccgctt ccaataacgc tggcaggcat
    17521 cgctctccat cagcttcgcg gcgtgccatg gcaggtgtcc ggtacggatg aagccgaggc
    17581 ggtcgcggac gctgagcatg cagatgagcc ggttggccgc gagcagctgc atgtactcct
    17641 cgacgtccag gtcctcggga gccgagagct tggcgaggtc ggggctggtg gacacctggg
    17701 ccagccagtc gagctggttg ccggtgagga acacctcgtt acgctcggcc tggtgccgtg
    17761 cgtcttgcct gagccgggtg gctccgacca cggcggtggt gagggagacg gcagcaccgg
    17821 cggcgaggac ggcggtggtg agcttcatcg gtcaaggaac ctttcccaga gcagatttgc
    17881 ggcaggtggg ctggcggacg gagaacccgg ggttctgctg gttcacgcgg cccccgcgag
    17941 gaggacggtc ggggtttcgt cggcggagct gtccggtgtg tagcggcggc acaccgcatt
    18001 gagagcgacg gcaaggggcg gcagacccac ggtggctctg cgtgcgtcga cggacccagg
    18061 ggcgcgcagc gggcacagct cgatcccatc ggtgctcagc aggaactggg tgccgtactc
    18121 ctgggcgctt ccactggtga cgagggcgcg atcgtgcagg tgagcccagt gctggacgag
    18181 tgcgtcgcca gcctggacag cgcgtccgag cagggtggtg gcggcgcgtt gaagggcgta
    18241 attgtcgtcg ctgtgcaggg cgatgctcca ggcggcgcgg gcgccgtcgg ggccgacgag
    18301 gcgatggccg ggccaatcat ggtcggccag gatggggtct gtacagcgag tggtgtaact
    18361 cgtggggtgg tagttacagt tgggccgcgg tgagacggcc gtcgaaggtg atgtcgaaag
    18421 cctggagagc cggcttccat cgcctggtcc aacgcttcgc tccggtcccg gtcgggtcca
    18481 ggctcattac tgcgaggtag acgcacttca gggcggcctg ttccgtgggg aagtgtccgc
    18541 gagcacggac ggccttgcgg attcgggcgt tcacggactc gatcgcgttg gtcgtgcaca
    18601 cgatccggcg gatctcgacg tcgaactgaa ggaagggcac gaactccgcc caggcccgct
    18661 cccacagccg gacgatggcc gggtacttcg caccccattc ctccgagaac tccaggaacc
    18721 tttccgtggc ggcatcctcc gtgggcgcgg tgtagaccgg ccggagagcc ttagcgatct
    18781 tctcccagtc ctgccggccc gcgtatttga agctgttacg aagcaggtga accacgcagg
    18841 tctgcacgat cgtcgcaggc cagacggtgt tcaccgcgtc ggggagtccg gtcagcccat
    18901 cgcagacaag catcaggacg tcgcgcacgc cccggttctt gatctcggtg aggacctgga
    18961 gccagtattt ggctccctcg ccgccatcgc caacccatag ccccaggatg tcccgggtcc
    19021 cctcggcggt cacggccaat gccatgtaga ccgggcgatt ggcaacctgc ccatccctga
    19081 ccttgacgtg cacacagtcg atgaagacga ccggatacac cgcgtccagc ggccggttct
    19141 gccattccac catgcccgcg accacactgt cggtgatcgt ggagatggtc gacttcgaca
    19201 cctcggtccc gtacacctgg gccaggtgcg cggagatctc accgtgcgtg agaccctttg
    19261 ccgacagtga cagcaccatc tcgtcgatcc cacccagacg ccgctgtcgc ttcttgacca
    19321 gcatcggctc gaaggacccc gcccggtccc gcgggacgga gatcccgacc gggccgacct
    19381 cggtggccac agtcttggac cggtggccgt tgcggtagtt ctcccgcccg ccctcggccc
    19441 gctcaccgtg ctcatgaccc aggtgatcag tcagctcacc ttccagcgcc gactccagca
    19501 cccgcttggt cagctgctgc agcaggccgc cctcaccggt cagcttcaac ccgtcggcct
    19561 gagctcgggt caccagctga ccgatcagct cgtcatccac ggcggccgcc agctcgccga
    19621 cgccactctc ggtaccggtc tcacgcatca cgtcagtcat caacttccgc ttcttgctcg
    19681 ggagttacac cggttaccgt acagacccgc gaccgccctc gtcgtcgtcg cctgccggga
    19741 cgggggctgg gggccagggg tgcgggtcac tgacgcacag gaagactccg tcgggggtcc
    19801 gggtgaggac gaccttcact ggaaccgagg actcatcctc cttgcgggcg tgctggaagg
    19861 cgttcgtcag tagctcggac gcagtgagag tgaccctcca gtcgagttcg gtcaggcccc
    19921 acagacggag gcacgcactg acgaggccac gcatgcccga gacggcagcg gcagtcagag
    19981 tgacgtcgat ttcgcatgct ccggaacgcg tccggaccgc agcgcttgtg ccgtccgtaa
    20041 ggggctgttg agcctccatc aggtctgcct tcacggggag tccctcgttc gacgaaatct
    20101 ctccaaccgg cgccggatgc ggtgtgtact ggggcggcgg ccgtgagcaa ccattgagcc
    20161 aggccgacag aaccgcgtgt agatcttgat acggaaacct cgatcttccg tttcgcgagc
    20221 gaggaacagc ccatgccaag acccgagaag caattgactc cggacgcgtc cccgcgtgac
    20281 tggttcggcc atgaactgcg gacctggcgt aagaagcgcg gccctctcac gcacgccgag
    20341 ttgggcacga atgtgcaggt cagcggttca ctcattgaga agatcgagaa ggggactgct
    20401 acctgttcga aagacttggc tgagcgcttg gacgaggtcc tgcagacggg gggagtcctc
    20461 acccgggcgt gggggatggt gttcgggcaa acggaaaaag cccgtcctga aacggaaagt
    20521 gcaccccctc gcagggcgga ggtgccggtt caggtccatg aaggccgcat cctgggcaga
    20581 ggtagtacaa cacctccaag cgggagccct gcctctgtgg accgtcgcgc cttcctcgcc
    20641 acgagcggcc ttgccgccat cgcccccata gacctcgtcc acctcgtgac cccagcagcc
    20701 ccccgggaga tcccgactca gatccgcccc cgcgagatca ggcaggtgaa gtcgctggcc
    20761 gatgtcatcc atcgccagga caacgagtac ggaggcggcg gcgcggtgcg tgaactcgcc
    20821 cgcggcgcca tcatgtgggg agccttcctg ctgccggtgc cctgccccga gcccctgcgg
    20881 cctgaactcc tggcctctgt ggctcggtta gggattgtcg tcggcgcctc gcagttcgac
    20941 gcgtacgctc acgacgatgc ccgagtcagc ttccggctag ccgctgagtg cgcggaagaa
    21001 gccggtgagt ggcatctgcg cgccaagacg tactcgttca tggcccggca ggaaatctgg
    21061 atcggagatc cggatactgg cctaacccac gcagagaagg ggttggtgcg ctccgaccga
    21121 ctcaccgcga ccgagcgtgc catgctgcac acggcacgcg cccgtgcctt cggcaagatg
    21181 cacgacgtag ccaacaccct gcgcgcggtc ggagaggccg acgccgcgtt cgaacactcg
    21241 gacccggtac aggatccgcc gtggatggcc tactacgact acgcccagca ccacggcgac
    21301 accgcccacg cgctgttcga cctcgcggtc cacgcggacc acgaccccgg gcaggcggcc
    21361 cgccgcttcg agatcgcggt caaaggacac ggcaacgcct tcgcccgctc gcgcgccatc
    21421 tccgagacaa aactcgcttc cctggtcatg gccaaaggcg atgatccgcg gcacgcggtc
    21481 gtactcggcc accgagcgct ggatgacgtc ggcaagctga cttcctgccg ggccgccgag
    21541 gacctgcggg aactcgcccg gttcgcaggc cgacaccgga gcctccccga ggccagcgac
    21601 ctgcgcgagc gcatcgcagc tacggtgcag gcgtgactac ttcgcccacg cccacccaag
    21661 ccgtacttaa ggaggcgtgc ctcgccgccg gcctcgacgc gaccaacgcc caaccgatac
    21721 ggatcgccga gaacgccatt tggcgtctgc ccgggggcac ggtggtgcgt atcgcccgcc
    21781 ctggccagtc cgccgccgca acacgcgagg ttcaggtcgc ccgctggctg gccacccagg
    21841 gcgtgcccgc cgtacgcgcc cttggcctgc ggcagccggt aatagccagc gggcaccctg
    21901 tgacgttctg gcaagagctg ccgccacacg aaatcgggac catcaccgac gtcgtcgtgc
    21961 tcctcaagca actgcacgcc ctgccgatac cagacctgcc actgggtgag ctggacccgt
    22021 tcgtccggct cgttgagcgc atcgacgcag cgagtacgac ttctgccgat gaccggttgt
    22081 ggctgaaggg ccggcttaaa gatctcaagc agcaatgggc ttcgaggccc aagggtcggc
    22141 cggagtgtgt aatccacggg gatgcatggg tcggcaacgt ggcgcgtacg gaggccggcc
    22201 cgatgttgct cgacttcgag cgctcttcgt tcggtccccc ggagtgggat ctcgtgtcga
    22261 ccgcagtgaa gctcaccact accggcgcag tatctgccga ggaatacgca gcattctgcg
    22321 agacctacgg cgttgacgtt acgaagtggg aagggtatga aatcctggct ggcgcacgcg
    22381 agttgcgtat ggtgacgtac gccgcgcagc atgcagccag ccgccctgaa tggcgacgcg
    22441 aggcgcaata ccgcattgac tgcttgcgcg gccgggccgg ggtgccgccg tggcgatgga
    22501 aggggatcat gtagcccact accagtgact cacgagtgca actcgtctta taggtggctt
    22561 tacccagttt agatgcaatg cctgatccgt caatctgact cggtgtcgcg atgcttccga
    22621 attgccaaag tgacgtattc gccgacggca gacaagaaat gccgcagaaa gactggatag
    22681 ctgtgcgagg gcatgtcaac gtacaacgtc ccgtggaaat ccaggccaga tggtgccacc
    22741 gctcctcagc gctcacttcc ccctaaaccg gttggggtgg gcgtcgcgag ggttggccag
    22801 ctagcgcaac tcaccttggg aggctcgtcc gtctgcttct gttaatctca tctactcgct
    22861 tcacttcgcc ctcggtggct gaacgactgg gcgcggccaa acggccggtg actaccctgc
    22921 ggtctccacg gggctctgtg tttccgtctg cgcggccgga cgtttcggtg aggatctcct
    22981 gtagcgagct accgcgacga tcgtgtcgtc aatgcgcacg tgccacgcca tccgggtgca
    23041 acaacccggt ggcccgggcc cccaagatcc ctgagcgccg cggcacggtg aatctggacc
    23101 ggcttacggc cgcctcgggc agcgcgcccg cagcccttag ctcgtacgta cttcccctgt
    23161 cggcaggaag gtcaagcaga catcgggcgc gtgacggtcg ggcaacatag ccgacgatcg
    23221 ccggttagcc aaaccggcga ttgccgcgac cattgagacg ttcgcctttc gactgcgctt
    23281 ggcggtggag tcgtggcgga cgcgggcagc ttcgcgatgg caagaggagg cgcggggcag
    23341 ttctgctgcg gcgtcttgcc gtaggcagcg tgcgccgccg acaggtggcc gtcctggcgc
    23401 actccgcgcg aggtgatgct gccatgcctc tgtcgctcct cgctctccca gcaaggaaac
    23461 cctgccatgc accgatcggc gataccgcct gcccccacga cttcctccgt agcagtacgt
    23521 acggccttcc tgaccgtgca agacgccgct gaatacctcg gcctctcaca ccacaccctc
    23581 tacgtctggc gccaccgccg tcagggaccg ccgagcttcc gcatgggccc ccgcggtcgc
    23641 gtcatgtacc gagtggaagc cctcgatgcc tgggtccgcg aacaggagca ggccgactcc
    23701 cgctccaact tggccctgaa cccgctgagc gcagatccac agcaacgcat ccgccccagc
    23761 gcctgacgtt ccgtccgtca ttgagcaccg tttgtacccc cgtcgaaaag gagattcccc
    23821 tggccggcta catcgaagac cgctggatca agaagaagaa ggacccggtc accgggaaac
    23881 gagagcgaac cgcccgctac ggcaagggca agcgatacaa ggccgctggc atacccggag
    23941 tccgagaccg atcctttgac accttggagg acgccaaggc gtggctccgg cgatcaagta
    24001 ccgaccagga gcgcggcgag ttcgtcgatc cacgggacgg ctccctaacc gtcgctgagt
    24061 acgtcgagcg gtactggatg ccgggtgtgc gtggtgaggc caagacgcgc aagggcatcg
    24121 atgagcggat tcggctacac gtgataccac acctgggcga tgtatcgctg aacgaggtgt
    24181 ctgcggccga gcttcgtgcc tacatagtca ggctcgaatc ctcgtgctcg ccgcagtacg
    24241 cccgcagcat cctctcgacg ctgtcgagcg tcctggagac agcggttgat gacaagcgtc
    24301 ttgctcggaa cccgatgagg tccaagtcgg tccgatggcc gaaactgcct gatgagcgtc
    24361 gtgaggcgtg gcctgaggcg ctggcacgga gcgtgcgtga tgagatcagc cagaggcacc
    24421 gtatagcggt aattcttggg cttgggtgcg gtctgcgtca gggggaagtg tttggcctga
    24481 gcatggagga cgtggaccac gcgcgcggag tcctccacgt ccgacgtcag gtgcaaatag
    24541 tcaatggccg gaagtacttt acccttccaa agggtggcaa aacccgcgtt gcggacatgc
    24601 cacgttccgt ggccgacgag ttggtgaagc atgccagggc ataccccggt gacaaggtcg
    24661 agcttccctg gggcggtcct gaatcggaca gggagcggaa gaagttcggc ctcgtactga
    24721 caacgaagta cgggaacgcg atcgcagcca acacgtggaa caccgagatc tggaagcctg
    24781 ccctggccag ggcaggtgtc atccctccgc gtgtcaaggg ggcgaaacct tggcagtggc
    24841 aagcggcgcc gaaggacggg ttccatgtgt tgaggcacac gtacgcatcc ctcgtgctgg
    24901 aggcaggaga gtcggtcgtc accctcgcca agtggttggg gcattcatcg ccgaccatca
    24961 cgctcgatca ctacgcgcac ttcatgccgg aggcggggaa gaaggggcgc agggcaatcg
    25021 atagcctgct gggggagcgg gcggaggaga gttccggccc aaactcccca gattctcccc
    25081 caggcccgat cctgagtgga gatgcgaccg tccgacgcgc gtaaacagcg aggtgagagc
    25141 ccgtatgttc accacccgcc ccaccctcca gggcaccttc ggcatggtgg cctccaccca
    25201 ctggctggcc tcgcagtcgg ccatggccgt gctggaggac gggggcaacg cctacgacgc
    25261 cgccgtggcc ggggccttcg tgctgcacgt cgtcgagccg cacctcaacg ggcccgccgg
    25321 agaggccccg atcctgctcg cgccggcgga cggagaggtg cgggtgctct gcgggcaggg
    25381 cgtggcgccg gccggggcga cggtcgcgca ctacaagggg ctcggactcg gcctggttcc
    25441 cggtaccgga ccgctcgccg ccgccgtccc cggagccgtc gacgcctggc tgctcctgct
    25501 gcgcgaccac ggcaccaagt ccctggccga cgtgctgaag tacgccatcg gctacgccga
    25561 gcacgggcac ccgcccgtgg agcgcttcac ggagaccgtc gagaccgtcc gggaactgtt
    25621 cgagacggag tggaagtcct ccgccgacgt ctacctgccg ggcggccgac cgccccgccc
    25681 cggcgagctg tttcgcaacc ccgccctcgc cgcgacctgg aagcggctgc tcgccgaggc
    25741 cgccggcgcg ggcgaccggg aggcgcggat cgacgcggcg cgggaggtct ggcgcgcggg
    25801 attcgtcgcc gaggccctcg tacggcaggc cgggcggccc accatggaca ccagcggtga
    25861 acgccacacc ggcaccctga ccgccgccga cctggccgac tggtccgccc actacgaggc
    25921 cccggcgacg tacgactgga acggctggac cctgtgcaag gcgggcccgt ggagccaggg
    25981 gcccgtcctg ctgcagcagt tggcgctgct cccgcccgaa ctgcccgcct acggctccgc
    26041 cgactacgtc cacctgctgg tggagggctg caagctcgcc atggccgacc gggaggcctg
    26101 gtacggcgac gcggacggcg cggaccgggt gccgctcgac gacctgctgt cgcccgggta
    26161 caacgcggag cggcggcaac gcgtcggtga caaggcgtcc ttcgaactgc ggcccggcgc
    26221 cccgggcggg cgcaccccgc ggctcagcgc gcacgcgctc gtcgcggccg tggagggcga
    26281 gggcctcgac gccctggggg tgggcgagcc gacggtcgcc aagagcccga cgtccccggt
    26341 cccgggcgag ccggacgtca ccgccgacgg gggcacccga ggcgacacct gccacctcga
    26401 catcgtggac cgctggggca acatggtctc ggccacgccc agcggcggct ggctccag
//
