LOCUS       NZ_CP116257            21086 bp    DNA     linear   CON 15-DEC-2024
DEFINITION  Streptomyces lienomycini strain DSM 41475 chromosome, complete
            genome.
ACCESSION   NZ_CP116257
VERSION     NZ_CP116257.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces lienomycini
  ORGANISM  Streptomyces lienomycini
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7863969)
  AUTHORS   Ding,W.
  TITLE     Streptomyces riduolalong sp. nov., isolated from the soil of Tibet
            exhibits against Gram-positive bacteria activity
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7863969)
  AUTHORS   Ding,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JAN-2023) School of life sciences and biotechnology,
            Shanghai Jiaotong University, 800 Dongchuan, Shanghai, Shanghai
            200240, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: GS De Novo Assembler v. August-2022
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_027947595.1-RS_2024_12_13
            Annotation Date                   :: 12/13/2024 16:03:07
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,183
            CDSs (total)                      :: 7,093
            Genes (coding)                    :: 6,850
            CDSs (with protein)               :: 6,850
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 243
            CDSs (without protein)            :: 243
            Pseudo Genes (ambiguous residues) :: 0 of 243
            Pseudo Genes (frameshifted)       :: 141 of 243
            Pseudo Genes (incomplete)         :: 121 of 243
            Pseudo Genes (internal stop)      :: 14 of 243
            Pseudo Genes (multiple problems)  :: 26 of 243
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:34:28
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1281279
            Orig. end                         :: 1302365
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP116257.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11086
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(3..1319)
                     /gene="aroA"
                     /locus_tag="BJ961_RS06085"
     CDS             complement(3..1319)
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016824681.1"
                     /locus_tag="BJ961_RS06085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_271320280.1"
                     /transl_table=11
                     /translation="MTVNPAHTALWPAPHASGAVDATVHVPGSKSVTNRALVLAALASE
                     PGWLRRPLRSRDTLLMAQALRAMGVEIEEGVGPEGTGEFWRVIPAGLRGPATVDVGNAG
                     TVMRFLPPVATLADGAVRFDGDPRSYERPLHGVIDALRTLGARVDDDGRGALPLTVHGG
                     GALEGGAVEIDASSSSQFVSALLLSGPRFNQGVEVRHTGSALPSVPHIRMTVDMLRSVG
                     AQVDTPESGGEPNVWRVTPGALLGRDLTIEPDLSNAQPFLAAALVTGGKVVIPDWPSRT
                     TQPGDRLREIFTEMGGSCELTEYGLVLTGSGAVHGIDVDLGEVGELAPGIAAVAALADS
                     PSTLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLHIRPSRLHGGVFHTYEDHRM
                     ATAGAVIGLGVEGVEIENVATTAKTLPDFPDLWTGMLGV"
     gene            complement(1452..2174)
                     /locus_tag="BJ961_RS06090"
     CDS             complement(1452..2174)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973759.1"
                     /locus_tag="BJ961_RS06090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_271320281.1"
                     /transl_table=11
                     /translation="MDHLASASLTSLWDEVSGTQPDPDLWVVVATLVAALAVVATRGSW
                     RIARNAITIAHEGGHGLVALLTGRTLTGITLHSDTSGLTVSRGKPHGLGMILTAVAGYT
                     APPLLGLGGAALLAAGRITLLLWLATALLVALLVMVRNAYGVLTVVVTGATFVLVSWLA
                     GPQVQAAFAYAVVWFLLLGGVRPAFELQAKRSRGGAGDSDADQLARLTHAPAGVWFFLF
                     HAVSLCSLIGGGRWLLEL"
     gene            2225..3040
                     /locus_tag="BJ961_RS06095"
     CDS             2225..3040
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="BJ961_RS06095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_271320282.1"
                     /transl_table=11
                     /translation="MCGRYAASRGPEDLAGIFEIEKWEPEESLDPDYNVAPTKEVYAVL
                     DRPLKDVEDPKPVRQLRKLKWGLVPSWSRTPEGGARMINARAETVHEKPSYRRAFATRR
                     CILPADGYYEWVTGTQERDLEVEGRRKRPRKQPYFVTPADGSVFAMAGLYEFWRDKTLP
                     DDHPQAWWVTCSVITTEAETAPLAVAPADGPHALADIHPRMPLMLTPDRWDDWLDPART
                     DPDELTSLLAPPPAGLMRAFPVPTAVSNVRNNGPELLKELEAPEEGTLF"
     gene            3063..3698
                     /locus_tag="BJ961_RS06100"
     CDS             3063..3698
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973757.1"
                     /locus_tag="BJ961_RS06100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_271416976.1"
                     /transl_table=11
                     /translation="MTEPVETDAGPARITWHAAVRPRLVLAVSHGAGGGVEARDLKALA
                     AALPAHGVSVALVEQPWRVAGKKLAPAPKTLDTGWRGVWPALTAPGLPVVSGGRSAGAR
                     VACRTARELGARAVLALSFPLHPPGKPEKSRADELLGAGVPTLVVQGGNDPFGRPEEFP
                     EAPRGTYELIEVPYADHGFAVPKRADTTQERALETITGGVARWAGSLD"
     misc_feature    complement(3883..3897)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.77"
                     /tool="antismash"
     gene            3953..4636
                     /gene="sigR"
                     /locus_tag="BJ961_RS06105"
     CDS             3953..4636
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="BJ961_RS06105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_003973756.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTEHGQAEQPEGRGTGAESTAERSARFERDALEFLD
                     QMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRKK
                     QREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKQALQAIPEEFRIAV
                     YLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARDRGLVPAGAGESNEA
                     KGSGS"
     misc_feature    3975..3990
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.19"
                     /tool="antismash"
     gene            4633..4944
                     /gene="rsrA"
                     /locus_tag="BJ961_RS06110"
     CDS             4633..4944
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136687.1"
                     /locus_tag="BJ961_RS06110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_271320283.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEILDHLYEFLDKEMPDSDCVKFEHHFEECSPCL
                     EKYGLEQAVKKLVKRCCGQDDVPGDLRAKVMGRLDLIRSGQSVPEHDVTAAPSASQES"
     gene            5074..6399
                     /locus_tag="BJ961_RS06115"
     CDS             5074..6399
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973754.1"
                     /locus_tag="BJ961_RS06115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_271320284.1"
                     /transl_table=11
                     /translation="MDAVPARARAYVACVALVALLSLRPLPSVHAPWWAVLLLAGLYAG
                     SELVARSRFVGTCYPVLLAGAFLLPPPAAALVALPGALLSPVPRRPFGLRRVWRAAQLT
                     LAVWAAACVHWRLDGRDAVVEPDFPYALLPAGAAVLAFCLVLTLLDGGILALADRVPAR
                     RAWRGLFSRSLAPIAVHGLAGLMMAVLWRSPYGPVAALLVLLPMCVAWWAFAQYHREQA
                     AHQATIRALVQAVDIKDGYTRGHSERVGRASMMIAHELGMDGERVETLRFAGILHDVGK
                     LGVPTRLLRKDGPLTPEERRVIELHPEYGHEMVRGIRFLGEARAAVLHHHERLDGSGYP
                     YGLAGDRIPESARVVAVADAFDAMTSTRSYSRARPVAAALEELQRCAGRQFDPRMVRAL
                     VRALARHGWRPSVTADGMSALPAAPSPGLDEGARDSVGKGAP"
     gene            6505..7842
                     /locus_tag="BJ961_RS06120"
     CDS             6505..7842
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444569.1"
                     /locus_tag="BJ961_RS06120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_271320285.1"
                     /transl_table=11
                     /translation="MTPPFRSRIPLSFPAPPRRERQATGTRTGAPPRSPVPPALLLVPG
                     CAGLLALGCLASVLWSGPEQRPVALAFGALVALGELTRRTGAEAREAAPLGAAGALAYA
                     LLGDVAGQPAHHGAAQTVTVVLAASLLGSVPHVARGDGPVLEHLARRVLTVAFAAVCFQ
                     PLSNQGVFRDWGGPAYALLLIALLALTTLCDAVLAAAPAHVRTGWPFGPLLRDELRGMV
                     GITSAVCATGAVMALAVSVAGLWALPVFSVPLLLAQLSYRRYAAVRATYRQTIASLARA
                     TEIAGYTPAGHAHRVAELGVAVGRDLGLTGTELTVLEYAALMHDIGQLSLVDPVPAGAT
                     AGLPLAEQRRIALLGGAVVRQTGVEAAVAVVVERQADPCREQPVAARIVRVVNAYEEKA
                     RDAGPGGVLTALEELRLATAGDYAPEVVEALARVLSRGSLTMRTAG"
     gene            7957..8937
                     /locus_tag="BJ961_RS06125"
     CDS             7957..8937
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="BJ961_RS06125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_271320286.1"
                     /transl_table=11
                     /translation="MRIFGKARHRPSASWRQATDRAFTLIGDGRYDDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARAAGLRAVALLGRDTGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLRAPGDATDAGEPLGMDLGSAAVRLSPEGEAEVVWGRRLDPARVEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERTTSAGHSYPVFDEIELWAPSPVPTWVVLLEAATESDRD
                     ALEQLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGEGEHLDPHDHSEPGHPGPLGHR
                     TDGQLWVPERECGVAAPAGLVKGLLDGWVADSPDSRDWRDLEEVC"
     misc_feature    complement(9036..9054)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.61"
                     /tool="antismash"
     misc_feature    9054..9068
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.6"
                     /tool="antismash"
     gene            9091..9741
                     /gene="def"
                     /locus_tag="BJ961_RS06130"
     CDS             9091..9741
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="BJ961_RS06130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptide deformylase"
                     /protein_id="WP_271320287.1"
                     /transl_table=11
                     /translation="MAQQDTDQQHPGVLPVDDEGFVVDTEDCEEREADWRGRGTSRPIT
                     VVGNPVLHKECEDVTDFGEEFQQLVADMFASQRTAEGVGLAANQIGVSRKVFVYDCPDD
                     EGVRHVGVVCNPKLVELPADSRRLDDSNEGCLSVPTAYAPLARPDYAEVTGQDEQGNPV
                     KVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAENEPRYPVVAND"
     gene            10001..11086
                     /gene="cyc1"
                     /locus_tag="BJ961_RS06135"
     CDS             10001..11086
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992851.1"
                     /locus_tag="BJ961_RS06135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_271416977.1"
                     /sec_met_domain="T1TS (E-value: 3.4e-64, bitscore: 216.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHAFSHGTTATPTAIAVPPSLRLPVIEAAFPRKLHPYWPKLQETT
                     RAWLLEKRLMPADKVAEYADGLCYTDLMAGYYLGAPDEVMQAIADYSAWFFVWDDRHDR
                     DIVHGRSAAWGRLRGRLHTALDSPGDHLHHEDALVAGFADSVRRLYAFLPRTWNDRFAR
                     HFHAVIEAYDREFHNRTRTIVPGVEEYLELRRLTFAHWIWTDLLEPSSGRELPDPVRKH
                     PAYRRAALLSQEFAAWYNDLCSLPKEIAGDEVHNLGISLITHHSLTLEEAIAEVRRRVE
                     ECITEFLEVEQDALRFADELADGTVHGKELSGAVRANVGNMRNWFSSVYWFHHESGRYM
                     VDSWDDRSTPPYVNNEAAGEK"
     misc_feature    10883..10885
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11083..12459
                     /locus_tag="BJ961_RS06140"
     CDS             11083..12459
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326965.1"
                     /locus_tag="BJ961_RS06140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_271320288.1"
                     /sec_met_domain="p450 (E-value: 3.4e-71, bitscore: 239.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESVNPETRSQAAPELREPPVAGGGVPLLGHGWRLARDPLAFM
                     SQLRDHGDIVRIKLGPKTVYAVTNPELTGALALSPDYHIAGPLWESLEGLLGKEGVATA
                     NGPLHRRQRRTIQPAFRLDAIPAYGPIMEEEAHALVERWQSGRTVDATSESFRVAVRVA
                     ARCLLRGQYMDERAERLCVALATVFRGMYRRMVVPLGPLYRLPLPANRRFNDALADLHL
                     LVDEIIAERRASGQKPDDLLTALLEAKDDNGDPIGEQEIHDQVVAILTPGSETIASTIM
                     WLLQALAAHPEHADRIRDEVEAVTGGRPVAFEDVRALTHTGNVIVEAMRLRPAVWVLTR
                     RAMAESELGGYRIPAGADIIYSPYAIQRDPKSYDDNLEFDPDRWLPERAKNVPKYAMKP
                     FSAGKRKCPSDHFSMAQLTLITAALATRYRFEQVAGSNDAVRVGITLRPHDLLVRPVER
                     "
     gene            complement(12463..13431)
                     /locus_tag="BJ961_RS06145"
     CDS             complement(12463..13431)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030121.1"
                     /locus_tag="BJ961_RS06145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GlxA family transcriptional regulator"
                     /protein_id="WP_271320289.1"
                     /transl_table=11
                     /translation="MLQNVAAVLLDGVHPFELGVVCEVFGIDRTDEGLPKYDFAVVSAE
                     GPTLSTHVGGLSVRTPYGLDRLAEADLIAVPAGSDFVRRDYPPALLNALRQAVDRGARV
                     LSVCSGVFVLAAAGLLDGRRCAVHWHHAAELARQYPGARVSPDVLYVDEDPVITSAGTA
                     AGIDACLHIVRKEQGPEVANRIARRMVVPPHRDGGQAQYIERPLPRSSCDTVGEVLAWM
                     EQHLDEEVTVEQLAVRAHMSPRTFARRFQQETGTTPYRWILRQRVLLAQQLLEATDETM
                     DTIAWRTGFGTAAALRHQFTRALGTTPHAYRRAFRGPEAAA"
     gene            13524..13772
                     /locus_tag="BJ961_RS06150"
     CDS             13524..13772
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973747.1"
                     /locus_tag="BJ961_RS06150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_271320290.1"
                     /transl_table=11
                     /translation="MNGNQIEALVGMLATFGLLVLMVLPSVIGIVRDKRVDRRIRQAQE
                     DRGERNRPSQKSSSRSTVPSTATWYAEGRRSKKLVSS"
     gene            complement(13685..14698)
                     /locus_tag="BJ961_RS06155"
     CDS             complement(13685..14698)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016437913.1"
                     /locus_tag="BJ961_RS06155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_271320291.1"
                     /transl_table=11
                     /translation="MTENTKNLLDPGFELTLRPMRYPDFYERYRDAIKNTWHVEEVDLH
                     SDVADLAKLSPEEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLSRQLFEE
                     AVHVQFYLTLLDTYLPDPEDRAAAFAAVENIPSIREKAEFCFRWMDSVESIDRLETKAD
                     RRRFLLNLVCFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSFAFD
                     VVDTVRKEEPELFDDALRREVTDMLREAVEAELQFARDLCGDGLPGMNTDSMRQYLECV
                     ADQRLTRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVEGTVDLDEDF"
     gene            complement(14698..17094)
                     /locus_tag="BJ961_RS06160"
     CDS             complement(14698..17094)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444560.1"
                     /locus_tag="BJ961_RS06160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_271320292.1"
                     /transl_table=11
                     /translation="MTIAPADPASATPVTAVPVTAAPAAEESDGPGAALLRTLTGLTAD
                     LPGADPGRVAAAALRGRSARADEAELRELATEAAAGLISEDPVYSRLAARLLTVGIRAE
                     AASQGVVTFTDSVATGHREGLIADRTAAFVRLHADRLDALVDPAADDRFGYFGLRTLYS
                     RYLLRHPITRKAVETPQHFLLRVAAGLAEDDSPRSVDEVAALYGLMSRLDYLPSSPTLF
                     NSGTRHAQMSSCYLLDSPKDELDSLYDRLHQVARLSKHAGGIGIAYSRVRARGSLIRGT
                     NGHSNGIVPFLKTLDASVAAVNQGGRRKGAAAVYLETWHADVEEFLELRDNTGEDARRT
                     HNLNLAHWIPDEFMRRVDADGTWSLFSPSDVPELVDLWGEEFDAAYRGAEEAGLARRSL
                     PARELYGRMMRTLAQTGNGWMTFKDTANRTANQTAAPGHVVHSSNLCTEILEVTDDGET
                     AVCNLGSVNLGAFVDPASGDMDWDRLDATVRTAVTFLDRVVDINFYPTEQAGRSNARWR
                     PVGLGAMGLQDVFFRLRLPFDSPEAKALSTRIAERIMLAAYETSADLAERSGPAPAWEK
                     TRTARGVLHPDHYGVEPVWPERWTALRARMATTGLRNSLLLAIAPTATIASIAGVYECV
                     EPQVSNLFKRETLSGEFLQVNSYLVDDLKRLGVWDARTREALREANGSVQGFSWIPEDV
                     RALYRTAWEIPQRGLIDMAAARTPYLDQAQSLNLFLETPTIGKLSSMYAYAWKRGLKTT
                     YYLRSRPATRIARAAGRAAVPEQAAPDPEAVACSLENPESCEACQ"
     regulatory      complement(17244..17341)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(17363..17377)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(17394..17408)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 25.12"
                     /tool="antismash"
     gene            complement(17433..17939)
                     /locus_tag="BJ961_RS06165"
     CDS             complement(17433..17939)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326961.1"
                     /locus_tag="BJ961_RS06165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_271320293.1"
                     /transl_table=11
                     /translation="MDFVIRRATAEEYDTLGEITAQAYLRDGLLDFGESDSYLDELRDV
                     AKRAAAAEVLVAVADGRVLGGATFVPCGGPMADIARPGEAEIRMLAVDREARGRGAGEA
                     LVRACVDRARAVDGCRSVVLSTQRTMRTAHRLYERLGFARTPDRDWNPLPELDDIMLLT
                     YELTL"
     gene            complement(18018..19628)
                     /gene="mctP"
                     /locus_tag="BJ961_RS06170"
     CDS             complement(18018..19628)
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006848 - pyruvate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="mctP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444565.1"
                     /locus_tag="BJ961_RS06170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="monocarboxylate uptake permease MctP"
                     /protein_id="WP_271320294.1"
                     /transl_table=11
                     /translation="MNDGVNGVALAVFILFFVLVTAMGFLAARWRRAENEHSLDEWGLG
                     GRSFGTWVTWFLLGGDLYTAYTFVAVPAAIYAAGASGFFAVPYTILVYPLIFTFLPRLW
                     SVSHKHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGG
                     EDTNWFVKDLPLLIAFGVLAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPIKLGG
                     FDDIFAAASDKFTESGKGGVVPDAGGQWTYATLALGSALALFMYPHSITATLSSRSREV
                     IRRNTTILPLYSLMLGLLALLGFMAIAAGVKVDNGQLAIPQLFENMFPDWFAGVAFAAI
                     GIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPAQETKVSKLVSLLVKVGALIFVLGM
                     DKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALLGGWAVGMVYGTVAAYGVASPT
                     QAHFGGSSDEIPGIGEIGYIGLTAFVLNVLVTVVLTFVLRAVKAPDGVDETKPGDYTAD
                     AGDAGVQVELPPATAGSSH"
     gene            complement(19625..19924)
                     /locus_tag="BJ961_RS06175"
     CDS             complement(19625..19924)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992859.1"
                     /locus_tag="BJ961_RS06175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_271320295.1"
                     /transl_table=11
                     /translation="MSEDTEVSTEPVVTPVRVVIGLCLVAPFVAMLWVGSYAKTDPAFI
                     GIPFFYWYQMAWVLISTLLTVTAYKLWQRDQRGRAAHSAAASSAPSAPKGGESR"
     misc_feature    complement(19996..20010)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.75"
                     /tool="antismash"
     misc_feature    20059..20073
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.91"
                     /tool="antismash"
     gene            complement(20071..20835)
                     /locus_tag="BJ961_RS06180"
     CDS             complement(20071..20835)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973740.1"
                     /locus_tag="BJ961_RS06180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_271320296.1"
                     /transl_table=11
                     /translation="MSTDVSSAENEGGATVRTARVPKYYRLKKHLLDMTRTQTPGTPVP
                     PERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRA
                     QGLEPTSQLLDIGYITADDRLAGLLDITAGGRVLRIERLRMANAEPMAIETTHLSAKRF
                     PALRRSLVKYTSLYTALAEVYDVHLAEAEETIETSLATPREAGLLGTDVGLPMLMLSRH
                     SRDRTGQPVEWVRSVYRGDRYKFVARLKRPQD"
     misc_feature    20968..20983
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.16"
                     /tool="antismash"
ORIGIN
        1 ccctaaaccc cgagcatccc ggtccagagg tcggggaagt cgggcagggt cttcgccgtc
       61 gtcgccacgt tctcgatctc cactccctcc accccgaggc cgatgacggc gccggcggtg
      121 gccatgcggt ggtcctcgta ggtgtggaag acaccgccgt gcagacggct cgggcggatg
      181 tgcaggccgt cggcggtctc ggtgacgtcg ccgccgagtt cgttgatctc cttggtgagc
      241 gccgccagcc ggtccgtctc gtgcagccgc aggtgggcca cgccgcgcag ggtcgagggg
      301 gagtccgcca gggcggcgac ggccgcgatg cccggggcca gctcgccgac ctcgccgagg
      361 tcgacgtcga tgccgtggac cgcgcccgaa ccggtgagga cgagcccgta ctccgtcagt
      421 tcgcaggagc cgcccatctc ggtgaagatc tcgcgcagcc ggtcaccggg ctgggtggtg
      481 cgggacggcc agtcgggaat cacgaccttg ccgccggtga ccagggccgc cgccaggaac
      541 ggctgggcgt tggacaggtc cggctcgatc gtcaggtccc ggccgagcag cgcacccggt
      601 gtcacccgcc agacgttcgg ttcgccgccg gactcggggg tgtcgacctg ggcgccgacc
      661 gagcgcagca tgtcgacggt catgcggatg tgcggcacgg aaggcagcgc ggaaccggtg
      721 tggcggacct cgaccccctg gttgaaccgc ggcccggaca gcagcagcgc gctgacgaac
      781 tgggaggacg acgacgcgtc gatctcgacc gccccgccct ccagggcacc gccgccgtgc
      841 acggtcagcg gcagcgcgcc gcgcccgtcg tcgtcgacgc gggcgcccag ggtgcgcagc
      901 gcgtcgatca cgccgtgcag cggacgctcg tacgaacgcg ggtcgccgtc gaagcggacg
      961 gcgccgtcgg cgagcgtggc gaccggcggc aggaagcgca tgaccgtgcc cgcgttgccg
     1021 acgtcgaccg tggcggggcc gcgcagcccc gccgggatga cccgccagaa ctcgccggtg
     1081 ccctccggac cgacgccctc ctcgatctcg acgcccatcg cgcgcagcgc ctgagccatc
     1141 agcagcgtgt cgcgggagcg cagcgggcgg cgcagccagc cgggctcgga ggcgagggcg
     1201 gccagcacca gggcccggtt cgtgaccgac ttggatccgg gcacgtggac ggtcgcgtcg
     1261 acggcgccgc tcgcgtgcgg tgcgggccag agggcggtgt gcgcggggtt cacggtcatg
     1321 gagcccactt taatggctga ggacgatcgg agatcttgat caaaagcggc gaaacctgac
     1381 cgaaaacgca acagtgcact tgccgtgcat atatgcggag ccttgggagg cgagtgggcg
     1441 cccgccgggc ctcacagctc cagcagccag cgccctccgc cgatcagcga gcacagcgac
     1501 accgcgtgga acaggaagaa ccacaccccc gccggcgcgt gcgtcagccg tgccagctgg
     1561 tcggcgtccg agtcgccggc gccgccccgc gaccgcttgg cctgcagctc gaacgccggg
     1621 cgcaccccgc cgagcagcag gaaccacacc accgcgtacg cgaacgccgc ctgcacctgg
     1681 ggcccggcca gccacgacac caggacgaac gtggcgccgg tgaccaccac cgtcagcacc
     1741 ccgtacgcgt tgcggaccat caccagcagc gccaccagca gcgccgtcgc cagccacagc
     1801 agcagggtga tgcgccccgc ggccagcagc gcggcgccgc cgaggccgag cagcggcgga
     1861 gcggtgtaac cggccaccgc cgtgaggatc atgccgagac cgtgcggctt gccccggctc
     1921 accgtcaggc cgctggtgtc cgagtgcagg gtgatcccgg tcagggtgcg gccggtcagc
     1981 agggccacca aaccgtgccc gccctcgtgg gcgatggtga tcgcgttgcg cgctatccgc
     2041 cacgacccgc gcgtcgcgac gacggcgagc gcggccacca gggtcgcgac caccacccac
     2101 aggtcgggat cgggctgggt gccggagacc tcgtcccaca gggaggtgag cgaggccgat
     2161 gcgaggtggt ccatgttcgg ggagggctcc tcgttgacgc gtggggtctg gcagtgtggc
     2221 acgtatgtgc ggacggtatg cggcgagtcg tggacccgag gatctcgcgg gaatcttcga
     2281 gatcgagaag tgggagcccg aggagagctt ggaccccgac tacaacgtgg cccccacgaa
     2341 ggaggtctac gccgtcctgg accgccccct gaaggacgtc gaggacccga agccggttcg
     2401 ccagctgcgg aaactgaagt ggggtctcgt cccctcctgg tccaggacgc ccgagggcgg
     2461 ggcccggatg atcaacgccc gcgcggagac cgtccacgag aagccctcct accgccgcgc
     2521 cttcgccacc cggcgctgca tcctgcccgc cgacggctac tacgagtggg tcaccggcac
     2581 gcaggagcgg gacctggagg tcgagggacg caggaagcgg ccccgcaagc agccgtactt
     2641 cgtgaccccc gccgacggct ccgtgttcgc catggccggg ctctacgagt tctggcggga
     2701 caagacgctg ccggacgacc acccgcaggc ctggtgggtg acgtgctccg tgatcaccac
     2761 cgaggccgag accgcgccgc tcgccgtcgc cccggccgac ggcccgcacg cgctggccga
     2821 catccacccc cggatgcccc tgatgctgac gccggaccgc tgggacgact ggctcgaccc
     2881 ggcgcgcacc gaccccgacg agctgacctc cctgctggcg cccccgcccg ccgggctgat
     2941 gcgggccttc cccgtcccca cggccgtgag caacgtccgc aacaacgggc cggagctgct
     3001 caaggagctg gaggcacccg aagagggcac actcttctga cgtgacggat gcgacagagg
     3061 ttgtgacaga gccggtcgag acggatgcgg gccccgcccg gatcacctgg cacgcggcgg
     3121 tgcggccccg cctcgtcctc gccgtgagcc acggcgccgg cggcggcgtc gaggcacgcg
     3181 acctgaaggc gctggcggcc gccctgccgg cccacggggt gagcgtcgcc ctcgtcgagc
     3241 agccctggcg ggtggccggc aagaagctgg cgcccgcgcc gaagaccctg gacaccggct
     3301 ggcggggcgt ctggcccgcg ctcaccgccc ccggcctgcc ggtggtctcc ggcggccgca
     3361 gcgccggcgc ccgcgtcgcc tgccgcaccg cacgcgaact gggcgcccgt gccgtcctcg
     3421 ccctgagctt cccgctgcac ccgccgggca agccggagaa gtcccgcgcc gacgagctgc
     3481 tcggggccgg cgtgcccacc ctcgtcgtcc agggcggaaa cgacccgttc ggcaggcccg
     3541 aggagttccc cgaggctccc cgcggcacgt acgagctgat cgaggtgccg tacgccgacc
     3601 acggcttcgc cgtgcccaaa cgggcggaca ccacccagga gagggcactg gagacgatca
     3661 ccggcggtgt cgcccggtgg gccggctcac tcgactgaac ggccgggaat gaccggcggg
     3721 cggtcactgt tgtgccggac atacgttgct gagaatcagc accgacgccg taggagagga
     3781 agtccgccgc atgggttcag ccttctgccc cagtcgtggc cgtgccgacc tggactggac
     3841 ggtgctgcac gcggcgaaga ccgcccctat tcgggcggcg ggcggaccgg atcgtcgtct
     3901 atcctccgat tcgagcggga ccggtctcgg tctcgcgacg tcactggagg aggtgggtcc
     3961 ggtcactggg accgacgcag ggaccgaaca cggccaggcg gagcagcccg agggccgggg
     4021 tacgggcgcg gagtcgaccg cggagcgcag cgcgcgcttc gagcgggacg cgctggagtt
     4081 cctcgaccag atgtactcgg ccgcgctgcg catgacgcgt aatccggccg acgccgagga
     4141 cctggtgcag gagacctacg ccaaggcgta cgcgtccttc caccagttcc gtgagggcac
     4201 caacctcaag gcgtggctgt accgcatcct caccaacacc ttcatcaact cctaccgcaa
     4261 gaagcagcgc gaacctcagc gcagcgcggc cgaggagatc gaggactggc agctcgcgcg
     4321 tgccgagtcg cacatgtcga cgggtctgcg ctccgcggag tcgcaggcgc tcgaccacct
     4381 gcccgactcg gacgtgaagc aggcgctcca ggcgatcccc gaggagttcc gtatcgccgt
     4441 gtatctggcg gacgtcgagg gctttgccta caaggagatc gccgacatca tggggacacc
     4501 catcggtacg gtgatgtccc ggctgcaccg tggacgccgt cagctgcgcg gcatgctgga
     4561 ggactacgcc cgcgaccgcg gcctggtccc cgccggcgcc ggagagtcga acgaagcgaa
     4621 aggctcgggg tcatgagctg cggagagccg cacgagacgg attgcagcga aatcctcgat
     4681 catctctacg agttcctcga caaggagatg ccggactcgg actgcgtgaa gttcgagcac
     4741 cacttcgagg agtgctcgcc ctgcctggag aagtacgggc tggagcaggc cgtgaagaag
     4801 ctggtcaagc gctgctgcgg acaggacgac gtgcccggtg acctgcgggc caaggtcatg
     4861 ggccgtctgg acctgatccg ctccgggcag tccgtgcccg agcacgacgt gacggccgcg
     4921 ccgtcggctt cccaggagtc ctgagcaagt cctgagcggt tcccacgccg ttccgagtca
     4981 ctcgtacgtg ctaatccgcg ggttatctgc ccgcggcctc cccgccgccg cctaggctcc
     5041 tgagcctgac aggcatggcc gggggagggg ctcatggacg cggtaccggc gcgggcgcgt
     5101 gcgtacgtcg cctgtgtcgc cctcgtcgcc ctgctcagcc tgcgccccct gccgtcggtc
     5161 cacgcgccct ggtgggcggt cctgctgctc gccgggctgt acgcgggctc cgagctggtc
     5221 gcgcggtccc ggttcgtcgg cacctgctat cccgtcctgc tcgccggtgc cttcctgctg
     5281 ccgccgcccg ccgcggcgct cgtggccctg cccggggccc tgctctcccc ggtgccgcgg
     5341 cgaccgttcg gcctgcggcg cgtctggcgg gccgcgcagc tgaccctcgc cgtgtgggcc
     5401 gccgcctgcg tccactggcg gctcgacggg cgggacgcgg tcgtcgagcc ggacttcccg
     5461 tacgcgctcc tgccggccgg ggccgcggtg ctcgcgttct gcctggtgct caccctgctg
     5521 gacggcggga tcctcgccct cgccgaccgc gtgccggccc ggcgggcctg gcgggggctg
     5581 ttctcccggt ccctcgcgcc gatcgccgtg cacgggctcg ccggactgat gatggcggtc
     5641 ctgtggcgca gcccgtacgg tccggtggcc gcgctgctcg tcctgctgcc catgtgcgtg
     5701 gcctggtggg cgttcgccca gtaccaccgc gagcaggcgg cgcaccaggc gaccatccgc
     5761 gcgctggtgc aggccgtcga catcaaggac ggctacacgc gcggccacag tgaacgcgtc
     5821 ggccgggcct cgatgatgat cgcccacgaa ctgggcatgg acggcgaacg cgtcgagacc
     5881 ctccgcttcg ccgggatcct gcacgacgtc ggcaagctcg gcgtgcccac ccggctgctg
     5941 cgcaaggacg ggccgctgac gcccgaggag cggcgggtga tcgaactgca ccccgagtac
     6001 gggcacgaga tggtccgcgg aatccgcttc ctgggagagg cccgcgccgc cgtcctccac
     6061 caccacgaac ggctggacgg cagcggctac ccctacggac tggccggcga ccggatcccc
     6121 gagtcggcgc gggtggtggc cgtggccgac gccttcgacg cgatgacgtc cacccgctcc
     6181 tacagcaggg cccgccccgt cgccgcggcg ctggaggagc tccagcggtg cgccggacgg
     6241 cagttcgacc cccggatggt gcgggcactg gtccgtgccc tcgcccgcca cggctggcgc
     6301 ccgtccgtga cggcggacgg catgtcggcc ctccccgccg ccccgtcacc cggcctcgac
     6361 gagggcgcgc gggacagcgt cggcaagggg gcgccgtgac ggaggcggga gtcccccgcg
     6421 cgcgaacggg gagcgcgggc cggcggctcc cggcggagcg acgcggcggc gcggagcgtg
     6481 ccggccgtgc gggccggggg cgccatgacg ccgcccttcc ggtcgcggat cccgctgtcc
     6541 ttcccggccc cgccccggcg ggagcgccag gccacgggga cgaggaccgg cgccccaccc
     6601 cggtccccgg tcccgccggc gctgctcctc gtccccggct gcgccgggct cctcgcgctc
     6661 gggtgcctcg cctccgtgct gtggtcggga cccgagcagc ggcccgtcgc gctcgccttc
     6721 ggggccctcg tcgccctcgg cgagttgacc cggcggaccg gcgccgaggc ccgggaggcg
     6781 gctccgctcg gagccgccgg agcactggcg tacgcgctgc tcggagacgt cgccgggcag
     6841 ccggcgcacc acggcgccgc ccagaccgtc accgtcgtgc tcgccgcctc actgctcggc
     6901 agcgtgcccc acgtggcccg cggtgacgga cccgtcctcg aacacctggc gcgacgcgta
     6961 ctcaccgtcg ccttcgccgc cgtgtgcttc cagccgctgt ccaaccaggg ggtcttccgc
     7021 gactggggcg gccccgccta cgcgctgctg ctgatcgcgc tgctcgccct gaccacgctg
     7081 tgcgacgccg tactcgccgc ggcacccgcg cacgtgcgca ccggttggcc cttcggaccg
     7141 ctgctgcggg acgagctgcg cggcatggtc gggatcacct ccgcggtgtg cgccaccggc
     7201 gccgtgatgg cgctcgcggt gagcgtcgcg ggcctgtggg cgctgcccgt cttctcggtg
     7261 cccctgctgc tcgcccagct gtcctaccgc cgctacgccg ccgtccgcgc cacctaccgg
     7321 cagaccatcg cctccctggc ccgcgccacc gagatcgccg gctacacccc ggccgggcac
     7381 gcccaccgcg tcgccgaact cggcgtggcc gtcggacggg acctggggct gaccgggacc
     7441 gaactgaccg tgctcgaata cgcggccctc atgcacgaca tcggccagct gagcctcgtc
     7501 gacccggtcc cggcgggagc caccgccggc ctgcccctcg ccgaacagcg gcggatcgcg
     7561 ctgctcggcg gcgccgtcgt ccgccagacc ggcgtcgagg cggccgtcgc ggtggtggtg
     7621 gagcggcagg ccgacccctg ccgggaacag ccggtcgcgg cccggatcgt gcgcgtcgtg
     7681 aacgcctacg aggagaaggc gcgcgacgcc ggtccgggcg gtgtcctgac ggcgctggag
     7741 gagctgcgcc tggccaccgc cggcgactac gctcccgagg tggtggaggc actggcccgg
     7801 gtcctttccc gcggcagcct taccatgcgc acggctgggt aacccatggg taatgagcgc
     7861 ccctacagcc gtacgtggtt tgatgcccgg gagagggtgt ccgggggcgc gaaaggcaca
     7921 gccagcccac tgaaacggaa ctggcaggcg ggaatcgtga ggatcttcgg caaggcacgg
     7981 caccggccct ccgcctcctg gcggcaggcc accgaccgcg cgttcacgct gatcggcgac
     8041 ggtcgctacg acgacgcggg ggcgctgctg acgcgggcgg cggacctgga gccctggctg
     8101 tcggagtcct ggttcaacct ggccctgctg cacaagttcc gccacgactg ggagcaggcg
     8161 agggcggccg gtctgcgggc cgtggcgctg ctcggccggg acaccggagc gcccgactgg
     8221 tggaacgtcg gcatcgccgc gaccgccctg caggactggc ccctggcccg ccgggcctgg
     8281 caggcctacg ggctgcgcgc ccccggagac gccacggacg ccggtgagcc gctcggcatg
     8341 gacctcggca gcgcggccgt acgactgtcc ccggaaggcg aggcggaggt cgtgtggggg
     8401 cggcggctgg accccgcccg cgtcgaagtg ctgtccatcc cgctgccgtc ctccgggcgg
     8461 cgctggggcg aggtcgtcct gcacgacggg gtgccgcacg gcgagcggac gacgtcggcc
     8521 gggcactcct accccgtctt cgacgagatc gagctgtggg cgccctcgcc cgtgcccacc
     8581 tgggtggtcc tcctggaggc cgccaccgag tccgaccggg acgccctgga gcagctggcc
     8641 gccgacgccg ggttcgccgc cgaggactgg tcgtcctccg tccggctgct gtgccggatg
     8701 tgctcggagt cccggatgcc gtccgacgag ggcgagggcg agcacctcga cccgcacgac
     8761 cacagcgaac ccggccaccc cgggccgctg gggcaccgca ccgacgggca gctgtgggtg
     8821 ccggagcggg agtgcggggt ggcggcgccg gccgggctgg tgaaggggtt gctggacggc
     8881 tgggtggccg acagcccgga ctcgcgcgac tggcgggacc tggaagaggt ctgctgaggt
     8941 tttcctacga gtgcggccac gtcgtggctg gtcgcgccca cgctgcggag ccgcatggcg
     9001 acactggccc gcgccccttt cgggggcgtg ccccccgtac cctgtatcaa gcatcaacct
     9061 cggtttcacc caggaaggca tacgtcggtc atggcccagc aggacaccga tcagcagcac
     9121 ccgggcgtgc tccccgtgga cgacgagggg ttcgtcgtcg acaccgagga ctgcgaggag
     9181 cgtgaggccg actggcgcgg gcgcggcacc tcgcgtccga tcacggtggt cggcaatccg
     9241 gtgctgcaca aggagtgcga ggacgtcacc gacttcggcg aggagttcca gcagctggtg
     9301 gccgacatgt tcgccagcca gcgcaccgcc gagggcgtgg gcctggccgc caaccagatc
     9361 ggcgtctccc ggaaggtctt cgtctacgac tgccccgacg acgagggcgt ccgccacgtc
     9421 ggcgtggtct gcaaccccaa gctggtcgaa ctgcccgccg acagccgccg cctggacgac
     9481 agcaacgagg gctgcctgtc cgtgccgacc gcctacgcgc cgctcgcccg ccccgactac
     9541 gccgaggtga ccgggcagga cgagcagggc aacccggtca aggtgcgcgg caccgggtac
     9601 ttcgcacggt gtttgcagca cgagacggac cacctgtacg ggtacctgta catcgaccgg
     9661 ctctccaagc gcgaacgcaa ggacgcactg cggcagatgg ccgagaacga gccccgctac
     9721 cccgtggtcg cgaacgactg acaccgcctc acccgcctca cgtctcccat gcgcacggcg
     9781 cctgtccggg tcttccccgg gcaggcgccg ttcgtctgtg cgcgccagtg gaaagccgcc
     9841 acacaacagg agaattccgg caccgagggg tagtgaatga agcaaatccg ttcccagaac
     9901 ggtcagttgt ggtgctgaat gggaagtgcg gggatacgca acggcgcacg ccccgctcag
     9961 cgagaggggt gcgccaccgg cggctgagag gggtttgttc gtgcatgctt tctcacacgg
    10021 caccacagcg acaccgaccg cgatcgcagt accgccatcg ctccgtcttc cggtgatcga
    10081 ggcggcattt ccccggaaac tgcatccgta ttggcccaag ctccaggaga cgacccgcgc
    10141 ctggctgctc gaaaagcggc tcatgccggc ggacaaggtc gcggaatatg ccgatggcct
    10201 gtgctacacg gacctcatgg cggggtacta cctgggcgcc cccgacgagg tcatgcaggc
    10261 gatagcggac tacagcgcgt ggttcttcgt ctgggacgac cggcacgacc gcgacatcgt
    10321 ccacggccgt tccgccgcct gggggcggct gcgcggccgc ctgcacactg cgctggactc
    10381 acccggggac catctgcacc acgaggacgc gctggtggcc gggttcgccg acagcgtgcg
    10441 gcggctctac gccttcctgc cccggacgtg gaacgaccgg ttcgcccggc acttccacgc
    10501 ggtgatcgag gcgtacgacc gtgaattcca caaccgcacc cgcaccatcg tgcccggcgt
    10561 cgaggagtac ctcgaactgc gccggctcac gttcgcgcac tggatctgga cggatctgct
    10621 ggaacccagc tcgggccgcg aactcccgga cccggtaagg aaacacccgg catatcgccg
    10681 ggcggcgctg ctgagtcagg aattcgccgc ctggtacaac gacctctgct cacttccgaa
    10741 ggagatcgcg ggagacgagg tccataatct cggcatcagc ctcatcacgc atcattcact
    10801 cacgctggaa gaagccatcg cagaagtccg gcgacgcgtc gaggaatgca tcaccgaatt
    10861 cctcgaagtg gaacaggacg ccttacggtt cgccgacgaa ctcgccgacg gaaccgtgca
    10921 cggaaaggaa ctgagcggcg ccgtgcgggc caacgtcggc aatatgcgga actggttcag
    10981 ttccgtctac tggttccacc acgagtccgg ccggtacatg gtcgacagct gggacgaccg
    11041 gtccacgccc ccgtacgtca acaacgaagc ggcaggtgag aaatgaccgt cgagtccgtc
    11101 aaccccgaga cccgctcaca ggcggcaccg gaactgcgcg agccacccgt cgcgggcggc
    11161 ggtgtgccgc tgctcggcca cggctggagg ctggcccgcg acccgctggc cttcatgtcc
    11221 caactgcgcg accacggcga catcgtgcgc atcaagctcg gcccgaagac cgtctacgcg
    11281 gtcacgaacc cggagctcac cggcgccctc gcgctgagcc ccgactacca catagccggc
    11341 ccgctctggg agtcgctgga gggactgctc ggcaaggagg gcgtggcgac cgccaacggc
    11401 ccgctccacc gccgccagcg gcgcaccatc cagccggcgt tccggctcga cgccatcccc
    11461 gcctacggcc cgatcatgga ggaggaggcc cacgcgctcg tcgagcgctg gcagtcgggg
    11521 cggaccgtcg acgccacctc cgagtccttc cgggtcgcgg tgcgcgtcgc cgcccgctgc
    11581 ctgttgcgcg gacagtacat ggacgagcgg gccgagcggc tgtgcgtggc gctcgccacc
    11641 gtcttccggg gcatgtaccg gcggatggtc gtcccgctcg gaccgctgta ccggctgccg
    11701 cttccggcca accgccgatt caacgacgcg ttggccgatc tgcacctgct ggtcgacgag
    11761 atcatcgccg agcgtcgcgc atccggtcaa aagccggacg atttgctcac ggcattgctg
    11821 gaggcgaagg acgacaatgg tgacccgatc ggggaacagg agatccacga ccaggtcgtc
    11881 gcgatactca cccccggaag tgaaaccatt gcctccacga tcatgtggtt gctccaggca
    11941 cttgccgcgc atccggaaca tgccgaccgc atacgcgacg aagtcgaagc ggtcaccggc
    12001 ggacgccccg tggcattcga agacgtccgc gcgctcacgc acaccggcaa tgtcatcgtc
    12061 gaggccatgc gtttgcggcc ggccgtatgg gtattgacgc ggcgtgcgat ggccgagagt
    12121 gaactcggtg gctatcgcat tccggccggg gcggacatca tctacagtcc gtatgcaatc
    12181 caacgcgatc cgaagtcgta cgacgacaac ctggagttcg accccgaccg gtggctcccg
    12241 gaacgcgcga agaatgttcc gaaatacgcc atgaagccgt tcagtgccgg caaacggaag
    12301 tgcccgagtg accacttctc gatggcgcag ctgactctga tcacggccgc gctcgccacc
    12361 aggtaccgct tcgagcaggt ggcgggctcg aacgacgccg tccgggtcgg catcaccctg
    12421 cggccgcacg acctgctggt caggccggtg gagaggtgac gctcaggcgg cggcctccgg
    12481 gcctcggaag gcacgccggt aggcgtgcgg ggtggtgccc agggcccggg tgaactggtg
    12541 cctcagggcc gccgccgtac cgaaaccggt gcgccaggcg atcgtgtcca tcgtctcgtc
    12601 cgtcgcctcc agcagttgct gggccagcag cacccgctgg cgcaggatcc accggtaggg
    12661 ggtcgtcccc gtctcctgct ggaagcggcg ggcgaaggtg cgcggcgaca tgtgcgcccg
    12721 gacggcgagc tgttcgacgg tgacctcctc gtcgaggtgc tgctccatcc aggccagcac
    12781 ctcgccgacg gtgtcgcagg aggagcgcgg cagcggccgt tcgatgtact gcgcctgccc
    12841 gccgtcccgg tgcggcggca ccaccatgcg ccgggcgatc cggttggcga cctccggccc
    12901 ctgctccttg cgcacgatgt ggagacaggc gtcgatgccc gcggcggtcc cggccgaggt
    12961 gatcaccggg tcctcgtcga cgtagagcac gtccggcgag acccgggccc ccggatactg
    13021 ccgggccagc tcggccgcgt ggtgccagtg caccgcgcac cgccgcccgt ccaggagtcc
    13081 ggcggcggcc agcacgaaga ccccggagca cacgctcagg acgcgtgcgc cccggtccac
    13141 ggcctgccgc agggcgttaa gcagtgcggg cgggtagtcc cggcggacga agtcgctgcc
    13201 cgccggcacg gcgatcaggt cggcctccgc cagccggtcg agaccgtacg gcgtgcggac
    13261 ggagagcccg ccgacatggg tgctcagcgt cgggccctcc gccgacacca ccgcgaagtc
    13321 gtacttcggc aggccctcgt cggtccggtc gatgccgaag acctcacaga cgacgcccag
    13381 ttcgaaaggg tgcaccccgt ccagcaggac cgcggccacg ttctgcaaca tgccgccagt
    13441 gtgccccgga agtggcagga aatcgaggcc ctacggcagt cctgccactc ccggtaagga
    13501 gtatccgacg cgacagtggt gtcatgaacg gaaaccagat cgaagccctc gtcggaatgc
    13561 tcgcgacctt cggactcctc gtcctcatgg tcctcccgtc ggtgatcggc atcgtgcgcg
    13621 acaagcgcgt cgaccgccgc atcaggcagg cccaggagga caggggcgag aggaaccggc
    13681 cgagtcagaa gtcctcgtcc aggtcgacgg tgccctccac cgccacctgg tacgccgaag
    13741 gacgccgctc gaagaagttg gtcagctcct gaaccccctg caactccatg aaggagaagg
    13801 ggttctcgga gccgtacacc ggggcgaagc cgagccgcgt cagacgctgg tcggccacgc
    13861 actcgaggta ctgccgcatc gagtcggtgt tcatccccgg gaggccgtcg ccgcacaggt
    13921 cgcgcgcgaa ctgcagttcg gcctcgacgg cctccctcag catgtcggtg acctcccgcc
    13981 ggagcgcgtc gtcgaacagc tccggctcct ccttgcgcac ggtgtcgacg acgtcgaacg
    14041 cgaaggacat gtgcatggtc tcgtcccgga acacccagtt ggtgccggtg gccaggccgt
    14101 gcagcagacc ccggctgcgg aaccagtaga cgtaggcgaa ggcgccgtag aagaacaggc
    14161 cctcgatgca cgcggcgaag cagaccaggt tgagcaggaa acggcgccgg tcggccttgg
    14221 tctccaggcg gtcgatcgac tccaccgagt ccatccacct gaagcagaac tcggccttct
    14281 cgcggatcga ggggatgttc tccacggccg cgaaggcggc ggcacggtcc tccgggtcgg
    14341 gcaggtaggt gtccagcagc gtcaggtaga actggacgtg gacggcctcc tcgaagagct
    14401 ggcgggacag gtacagccgc gcctcgggcg agttgatgtg cttgtagagg gtcagcacca
    14461 ggttgttcgc gacgatcgag tcaccggtgg cgaagaaggc caccagccgc ccgatcaggt
    14521 gctgctcctc ggggctgagc ttcgccaggt cggcgacgtc cgagtggagg tcgacctcct
    14581 ccacgtgcca cgtgttcttg atggcgtccc ggtagcgctc gtagaagtcc gggtagcgca
    14641 tgggacgcag ggtcagctcg aagcccgggt cgagcaggtt cttggtgttc tcggtcatta
    14701 ctggcaggcc tcgcaggact cggggttctc cagggagcag gcgaccgctt cgggatccgg
    14761 ggcggcctgc tcgggaacgg cggctcggcc cgcggcgcgg gcgatgcggg tcgcggggcg
    14821 cgagcgcagg tagtacgtgg tcttcaggcc ccgcttccag gcgtacgcgt acatcgagga
    14881 gagcttcccg atggtcggcg tctccaggaa caggttcagc gactgggcct ggtcgaggta
    14941 cggggtgcgg gcggcggcca tgtcgatcag gccgcgctgc gggatctccc aggcggtgcg
    15001 gtacagcgcg cggacgtcct cggggatcca ggagaagccc tgcaccgagc cgttggcctc
    15061 gcgcagcgcc tcacgggtgc gcgcgtccca cacgccgagc cgcttgaggt cgtccaccag
    15121 gtacgagttg acctggagga actcgcccga cagcgtctcg cgcttgaaca ggttggacac
    15181 ctgcggctcg acgcactcgt acaccccggc gatggaggcg atggtcgcgg tcggggcgat
    15241 cgccaggagc agggagttgc gcagcccggt cgtggccatg cgtgcccgca gcgcggtcca
    15301 gcgctccggc cagacgggct cgacgccgta gtggtccggg tgcagcacac cccgggccgt
    15361 acgggtcttc tcccaggccg gggcggggcc gctccgctcg gccaggtcgg cggacgtctc
    15421 gtacgcggcc agcatgatcc gctcggcgat gcgggtcgac agggccttcg cctcgggcga
    15481 gtcgaagggc aggcgcagcc ggaagaagac gtcctggagg cccatcgcgc cgaggccgac
    15541 cggacgccag cgggcgttgg agcggcccgc ctgctcggtc gggtagaagt tgatgtcgac
    15601 gacccggtcc aggaacgtca cggcggtgcg gacggtggcg tccagccggt cccagtccat
    15661 gtcgccgctc gcggggtcga cgaacgcgcc gaggttgacc gagcccaggt tgcagaccgc
    15721 cgtctccccg tcgtcggtga cctccaggat ctccgtgcag aggttcgagg agtggacgac
    15781 gtgcccgggg gccgccgtct ggttcgcggt ccggttggcg gtgtccttga aggtcatcca
    15841 gccgttgccg gtctgcgcga gggtgcgcat catccggccg tacagctccc gggcgggcag
    15901 cgacctgcgg gcgagccccg cctcctccgc cccgcggtag gcggcgtcga actcctcgcc
    15961 ccacaggtcg accagttccg gcacgtcgga gggggagaac agcgaccagg tcccgtcggc
    16021 gtccacccgg cgcatgaact cgtccgggat ccagtgcgcg aggttcaggt tgtgcgtacg
    16081 gcgggcgtcc tcgccggtgt tgtcccgcag ttccaggaac tcctcgacgt ccgcgtgcca
    16141 ggtctccagg tagaccgccg ccgcgccctt gcgccggccg ccctggttca ccgcggcgac
    16201 cgaggcgtcc agcgtcttca ggaacgggac gatgccgttg gagtgcccgt tggtgccgcg
    16261 gatcagcgaa ccccgggcgc ggacgcggga gtaggcgatg ccgatgccgc cggcgtgctt
    16321 ggacaggcgg gcgacctggt ggaggcggtc gtagagggag tccagctcgt ccttgggcga
    16381 gtccaggagg tagcaggacg acatctgggc gtgccgggtg ccggagttga agagggtggg
    16441 ggaggagggg aggtagtcca ggcggctcat caggccgtag agcgcggcga cctcgtcgac
    16501 cgagcggggg gagtcgtcct cggcgagtcc ggcggcgacc cgcagcagga agtgctgggg
    16561 cgtctcgacg gccttgcggg tgatcgggtg gcgcagcagg tagcggctgt acagggtgcg
    16621 cagtccgaag tagccgaagc ggtcgtcggc ggccgggtcg accagcgcgt cgagccggtc
    16681 cgcgtgcagc cgtacgaagg ccgcggtgcg gtcggcgatc aggccctcgc ggtggccggt
    16741 ggcgacggag tcggtgaagg tcacgacgcc ctgggaggcg gcctcggcgc ggatgccgac
    16801 ggtcagcagc cgggcggcca gccgggagta gaccgggtcc tcggagatca gcccggcggc
    16861 cgcctccgtg gccagctcgc gcagctccgc ctcgtccgcg cgggcggacc ggccgcgcag
    16921 cgcggcggcg gccacccggc cggggtcggc accgggaagg tcggcggtca gcccggtcag
    16981 ggtccgcagc agggcggcac cggggccgtc ggactcctcg gccgcgggcg cggctgtcac
    17041 cgggacggcg gtcaccggcg tcgctgaagc cgggtcggct ggcgcgatgg tcacgtgggg
    17101 cactccctcg ctcggcacgg ggcctggcgg agggagggca gggggcagct cacgagcgca
    17161 cgcggcgtcg cgtccaccgg cccactccac gaggcccgga cgtcatggca cccggaccgg
    17221 gacggccggg cacactgtcg acaggtcctc ggactggaca ggcgtgcgcg cacgtgtgaa
    17281 gacgtacgga tgcacgcaag tacaccgttg cgggacagtt ccggattcgc accggattcc
    17341 cctgcggcga cagcgagcac gagcatacat cttgtgccgg gggacgcgag cacccccaga
    17401 tgttgtgtcc aggcagggtg ccgcgccccg tgtcagagcg tcagttcgta ggtgagcagc
    17461 atgatgtcgt ccagctccgg caggggattc cagtcgcggt cgggcgtgcg ggcgaagccc
    17521 aggcgctcgt agaggcggtg ggcggtgcgc atggtgcgct gggtcgacag cacgacgctc
    17581 cggcagccat cgacggcccg cgcgcggtcg acgcaggccc gcacgagggc ctcgcccgcc
    17641 ccgcgaccgc gtgcctcgcg gtcgacggcg agcatgcgta tctcggcctc gccggggcgc
    17701 gcgatgtccg ccatggggcc gccgcacggc acgaaggtcg cgccgccgag cacccggccg
    17761 tcggccacgg cgaccagcac ctcggcggcc gcggcgcgct tggccacgtc gcgcagctcg
    17821 tccaggtagg agtcgctctc cccgaagtcg aggaggccgt cgcgcaggta ggcctgcgcg
    17881 gtgatctcgc cgagggtgtc gtactcctcg gccgttgccc gccggatgac gaagtccatg
    17941 acgccgagtg tgcccgacgg gtacgacaac gggccgccgg atttctccga cggcccgtct
    18001 cgttcgcgcg gcggggatca gtgcgagctg cccgccgtgg ccggcggcag ctccacctgg
    18061 acaccggcgt cgcccgcgtc cgccgtgtag tcgcccggct tggtctcgtc gacgccgtcg
    18121 ggcgccttga ccgccctcag gacgaaggtg aggaccaccg tgaccaggac gttcagcacg
    18181 aacgcggtga gaccgatgta gccgatctcg ccgatgccgg ggatctcgtc ggaggagccg
    18241 ccgaagtgcg cctgcgtcgg cgaggcgacc ccgtaggcgg cgaccgtgcc gtagaccatg
    18301 ccgaccgccc agccgccgag cagcgcccag cggtggaacc agcgggtgaa cagcccgccg
    18361 accagggccg ggaaggtctg caggatccag atgccgccga gcaactggaa gttgatcgcg
    18421 acggtcttgt ccatgcccag gacgaagatc agcgcgccca ccttcaccag cagcgacacc
    18481 agcttggaga ccttggtctc ctgggccggt gtggcgtccg gcttgatgaa gtccttgtag
    18541 atgttgcggg tgaagaggtt cgcggccgcg atcgacatga tcgccgccgg gaccagggcg
    18601 ccgatgccga tcgccgcgaa ggccacgccc gcgaaccagt ccgggaacat gttctcgaac
    18661 agctgcggga tcgccagctg gccgttgtcc accttcaccc cggccgcgat cgccatgaag
    18721 cccagcagcg cgagcagacc cagcatcagc gagtacagcg gcaggatcgt cgtgttgcgg
    18781 cggatcacct cacggctgcg cgaggacagc gtggcggtga tcgagtgcgg gtacatgaag
    18841 agcgccaggg ccgagccgag cgcgagggtc gcgtacgtcc actggccccc cgcgtccggc
    18901 accaccccgc ccttgcccga ctcggtgaac ttgtcgctcg ccgccgcgaa gatgtcgtcg
    18961 aagccgccca gcttgatcgg gatgtagatg atcgccaccg cgatgacgat gtagatcagc
    19021 gtgtccttca cgaacgcgat cagcgcgggc gcgcgcagcc ccgacgagta ggtgtacgcc
    19081 gccagcacgc cgaaggcgat cagcagcggc aggtccttga cgaaccagtt ggtgtcctcg
    19141 ccgccgccga cgcccatcac gtcgaggacg gcctggatgc cgaccagctg gagcgcgatg
    19201 tacggcatgg tcgccaggat gccggtgacg gcgaccgcca gcgacaggcc cttggagccg
    19261 aaccggccgc gcacgaagtc cgaggtcgtg acgtacccgt gcttgtgcga caccgaccac
    19321 aggcggggca ggaaggtgaa gatcagcggg tagaccagga tcgtgtacgg gaccgcgaag
    19381 aagccggagg cgcccgccgc gtagatcgcc gccgggacgg ccacgaacgt gtaagccgtg
    19441 tacaggtcgc cgcccagcag gaaccaggtg acccaggtgc cgaacgagcg gccgccgagg
    19501 ccccactcgt cgaggctgtg ctcgttctcg gcccggcgcc agcgggcggc caggaagccc
    19561 atggcggtca cgaggacgaa gaagaggatg aagacggcga gtgcgacgcc gttcacgccg
    19621 tcgttcatcg cgactcaccg cccttcggag cggagggcgc ggaggaggcg gcggcggagt
    19681 gggcggcacg cccgcgctgg tcgcgctgcc acagcttgta cgcggtcacg gtcagcaggg
    19741 tggagatcag cacccaggcc atctggtacc agtagaagaa cgggatgccg atgaaggccg
    19801 ggtccgtctt cgcgtaagag ccgacccaca gcatggcgac gaacggtgcg acgagacaga
    19861 gcccgatgac gacgcgcacc ggcgtcacca ccggctccgt gctcacttct gtgtcttctg
    19921 acatgcggcg gctccgtccc ctcgctgatc acctcgtgca gtgcgcacga aatgtaggtg
    19981 acggtgtcga gacagcggaa gacctcgtcc gtatatcggt cctcaactgc aacttcgcgc
    20041 ctgcgcgcgg gatggtatgg cagatatgtt ctagtcctgc ggccgcttga ggcgggccac
    20101 gaacttgtag cggtcgcccc ggtacaccga ccgcacccac tccaccggct ggccggtgcg
    20161 gtcccgcgag tgccgggaga gcatcagcat cggcagaccg acgtcggtgc cgagcagacc
    20221 ggcctcgcgc ggggtggcca gggaggtctc gatggtctcc tcggcctcgg cgagatggac
    20281 gtcgtacacc tcggcgagcg cggtgtagag ggacgtgtac ttcaccagcg agcggcgcag
    20341 ggccgggaag cgcttcgcgc tgaggtgggt ggtctcgatg gccatcggct ccgcgttggc
    20401 catgcgcagc cgctcgatgc gcagcacccg gccgccggcc gtgatgtcca gcagtccggc
    20461 gagccggtcg tcggcggtga tgtagccgat gtccagcagc tgcgaggtgg gttcgaggcc
    20521 ctgggcgcgc atgtcctcgg tgtacgaggt gagttgcagc gcctgcgaca ccttgggctt
    20581 ggcgacgaag gtgcccttgc cctggatgcg ctccaggcgg ccctcgacga ccagctcctg
    20641 gagagcctgg cgcacggtgg tgcgcgaggt gtcgaactcg gcggccagtg tgcgctcagg
    20701 tgggaccggc gtgcccggcg tctgggtccg ggtcatgtcg agcagatgct tcttcagacg
    20761 gtagtacttg ggcacgcgcg cggtacggac ggtcgcccca ccctcgttct ccgcactgct
    20821 gacgtcggtg ctcatgctct gccttcccgg ctccgggtgc cgaagcgacc gctaaccctg
    20881 tcggccacgg ctcacatcgt ggcacggctt cgcgccgggg tgaccccgca cgctccgtga
    20941 tcccttctgt atacctgcga gacccccctt ggtctagtcc acaggcgggt tcgacgccgc
    21001 tggtacgcgc gttcggaacc gtaccggcac gtcattcggt ggggggtggt acacccggtc
    21061 ccggtccgcc cgatctgccg cttgcg
//
