LOCUS       NZ_CP115936            21125 bp    DNA     linear   CON 13-JUL-2024
DEFINITION  Streptomyces goshikiensis strain CGMCC 4.1796 chromosome, complete
            genome.
ACCESSION   NZ_CP115936
VERSION     NZ_CP115936.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces goshikiensis
  ORGANISM  Streptomyces goshikiensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7239828)
  AUTHORS   Mo,P.
  TITLE     The genome sequence of Streptomyces sporoverrucosus CGMCC 4.1796T
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7239828)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 8.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 184.03x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_027942015.1-RS_2024_05_27
            Annotation Date                   :: 05/27/2024 07:01:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,266
            CDSs (total)                      :: 7,170
            Genes (coding)                    :: 7,009
            CDSs (with protein)               :: 7,009
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 55 of 162
            Pseudo Genes (incomplete)         :: 131 of 162
            Pseudo Genes (internal stop)      :: 14 of 162
            Pseudo Genes (multiple problems)  :: 36 of 162
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:49:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6847516
            Orig. end                         :: 6868641
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP115936.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Mo Ping.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21125
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="23"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21125
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21125
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11125](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11125
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(406..420)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.76"
                     /tool="antismash"
     gene            complement(519..1196)
                     /db_xref="GeneID:91413241"
                     /locus_tag="PET44_RS30095"
                     /old_locus_tag="PET44_30095"
     CDS             complement(519..1196)
                     /codon_start=1
                     /db_xref="GeneID:91413241"
                     /inference="COORDINATES: protein motif:HMM:NF020387.4"
                     /locus_tag="PET44_RS30095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_30095"
                     /product="RES family NAD+ phosphorylase"
                     /protein_id="WP_008744158.1"
                     /transl_table=11
                     /translation="MARPAKLPGKLAGTPHQVVWPAGTTLYRVHRKSRSAADFNATVVD
                     HHFGGTRFDSTPNDEYSYLYLAPSAETALVESLLKELPVDDGEPRVVSYSAIEDRRLSR
                     LELLTDVTLLSLLDRRATSAVNQGTWLIQSESPDYPFTRRWGHWLRGQADWAQGLIWTS
                     RQNHPEPTAVLFGDRFGPLVREDGNEVLRPVPGGIDLDDSAGRRWLDSALDPYCARVGA
                     PAD"
     gene            complement(1198..1806)
                     /db_xref="GeneID:91413242"
                     /locus_tag="PET44_RS30100"
                     /old_locus_tag="PET44_30100"
     CDS             complement(1198..1806)
                     /codon_start=1
                     /db_xref="GeneID:91413242"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PET44_RS30100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PET44_30100"
                     /product="DUF3168 domain-containing protein"
                     /protein_id="WP_271244983.1"
                     /transl_table=11
                     /translation="MLGLFANVSDDDGLRAVGEAVAAHVRGRLPADDPALRRWRSTMAP
                     DRSAAPGLIRRMATRHGHHVPVRSSGARPSHHRAEPAGPAAPSSWDRIRERLLSASSLS
                     EAQVRDVLRQDPRHPHLIRLTRKGGEVRLPSFQFQEDCVPVPLVLAINEVLRASKDPWG
                     AADWWLGPNHWLAAPPAEVLGSVPDDELMAAARAVGEGD"
     misc_feature    1833..1846
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(1840..1856)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 14.74"
                     /tool="antismash"
     misc_feature    1891..1905
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     misc_feature    2004..2016
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.14"
                     /tool="antismash"
     gene            2247..7661
                     /db_xref="GeneID:91413243"
                     /locus_tag="PET44_RS30105"
                     /old_locus_tag="PET44_30105"
     CDS             2247..7661
                     /codon_start=1
                     /db_xref="GeneID:91413243"
                     /inference="COORDINATES: protein motif:HMM:NF024180.4"
                     /locus_tag="PET44_RS30105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_30105"
                     /product="CHAT domain-containing protein"
                     /protein_id="WP_271244984.1"
                     /transl_table=11
                     /translation="MDASGSDDIRALEREIAALRERARVLHPGGQERWNTEADLAELLF
                     VHALEVASAGAATAAGAPPLPEGLAEARALLDRLLSQRRPGSASYHWACLLAARAARGE
                     AELTGDPDARDAAIERFETAIAPLPPYGPDTFPPLPGEPEWWTPALAVDARCELGLALY
                     NRSRELTGGSRSRDLDRIVTLLTPVVDGPEAGLAQDLQVTLACLGLALADRSRAPGHRG
                     PDRPADRTEAIGRLRAARETPSEDEVPGAVPFQLALLLFCEHDDGCGGSEGADGRGPSA
                     RRTGELDEALALLWPLTLDPSADGGEATELATMTARHLYEHDGGPAAETALIEWHRRAI
                     DHPGTQRRQVRANRTDLALLLIDRAERGATAPAPGTPAPGTPAPGTPAPGTPAPGTPSR
                     SDDLGEAARHLELALDDLALKERAPSVRLRAEDDPPETDADRAEERLNMLLGLVTLLSM
                     LLPESSDDARLDRLIRRGQELIEVIPDADTERGGACLRLALALFERTSRRTLPQLPALL
                     MRAMTPDRADPGISLVANVPGVREDNELAIALLRTGVGLYGYEDELYEAAAIALAVSLL
                     IGYTVRLPERDTALIRDAVHWFRIVLDRVPEGGELHSPDLEDLFIGALLNSVWTSEPFV
                     RAQTGSWRDGEGIPDVSRNQSVEDDLQSLRHLLETAVRRREQPVPVYEMVLLLITFMRG
                     KGELDDAEARHWRDRLRRASAYTDPAEESLKGFLLLAAGAFGYELARRGAAGPAELAEA
                     DRLLREGARHMPPGSDFAEWAEGLRATGPATLIQQLLGVFMGGASAPGAAAAGAPGAAR
                     RPADDAVRAPGPARPPGSARPPGPVRPPARSAPAEAEDIPLSAAAVLPGDGSPYPFTEP
                     VGRVLEIVTGPAGPAGPAEQRSAPVMAAHALALHRRWLHESEIADLTDAVTLTRRAIAA
                     AEGADGPLADRLSLLLAGMLRDRYLLIGDRMDLQAARTAYERLRDRSDPRAPHPELAML
                     LARPGAEGQPDLAALLRPARPAAPGAFSAELLAAAALTGLLAAREDGAADRAAAELAEA
                     GEALPADHPLLPAVLSESGLFRATRAARADGLAALREAVEDVVRAAALCPPGSAHRAPL
                     LLRAAAVLCAHSDALDAADPAGPAAPGSRASSLDRGIGLLSGAVDEAGPSFHGARARCR
                     YGLGSLLLTRFRRSRDRADLDRAVGLLRDARTAVLSRPGDPFTVLLTRALAEALRAHGP
                     EDPDHRAQSREAAKSVLAAHGRAVLLQTGTETALDSARAAGSDMMRLVEWCLTDGRTEE
                     ALEALELGRGLVLNAATVAASVPELLEREGRPELAQAWRRADPGRVPGTPADGPVVIPD
                     GLRLLVLQALEGGPAERRILSAPTPAEIGRALRTVGHDALVHLIPGRDGSGDALIVTAT
                     GAVERLRLPGLCVTDDGPAAAYGEALQEFAAATREPVVLPGEDDPAVMWELYRRGRKRL
                     GRASDRWRGALEPLCSWAGEVAMAAVIEHVGAGRRHRPARLVLSPVGMLGMVPWHAARL
                     PGAPGVSAEPGGGYACGRAVISYCSTSRQLVEVAARARLPWNGAQAVVADPGGTPAMHE
                     EARLIAALYPGATVVGPVDDVPEPGGPGSRPPSRPATAAAVAPLLPGRGGSSVAVCHVN
                     CHATARATPSASSLDLHPAAPVPQVLTLAEIQALAHGRDPSAPGGLLVLANCTSDLTLA
                     DYDEALTLSTAFLTAGAASVVGSLWAIADDIRTSMVMYVFHHYLTGRGLPGHPEAVGSP
                     ADALRAAQLWMLDPHRIVPPALSAVMEERPGLDLDAPHIWAAFTHHGH"
     misc_feature    7678..7687
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.37"
                     /tool="antismash"
     misc_feature    7684..7698
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.36"
                     /tool="antismash"
     misc_feature    7688..7702
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            7798..8283
                     /db_xref="GeneID:91413244"
                     /locus_tag="PET44_RS30110"
                     /old_locus_tag="PET44_30110"
     CDS             7798..8283
                     /codon_start=1
                     /db_xref="GeneID:91413244"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PET44_RS30110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PET44_30110"
                     /product="hypothetical protein"
                     /protein_id="WP_053065838.1"
                     /transl_table=11
                     /translation="MVAALKFAHSNLDGLKVKELVDKKGIEWYINHCAALAATTGVASG
                     MGGPATMVLGVPADMANTIAQQFRVTMAVIYHKTGSYSLSFDEFMKIVAVSLGVEVGTQ
                     VVVRVAAEIFKRLTAKIAGKFIPLLGGVIGGGLNYGFIKAQGKAMLALDFDKLSRSA"
     misc_feature    8266..8268
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8266..9414)
                     /db_xref="GeneID:91413245"
                     /locus_tag="PET44_RS30115"
                     /old_locus_tag="PET44_30115"
     CDS             complement(8266..9414)
                     /codon_start=1
                     /db_xref="GeneID:91413245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016827487.1"
                     /locus_tag="PET44_RS30115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_30115"
                     /product="DUF6596 domain-containing protein"
                     /protein_id="WP_271244985.1"
                     /transl_table=11
                     /translation="MNEALLRSLTPSVLGILVRRGADFAAAEDALQEALVEAVRVWPAD
                     MPREPKGWLVTVAWRRYLDAARSDTARRRREDLVEEEPAPGPAPGVDDTLQLYFLCAHP
                     ALTPSSAVALTLRAVGGLTTRQIAQAYLVPEATMAQRISRAKRTVSGVRFDQPGDVATV
                     LRVLYLVFNEGYSGDVDLAAEAIRLTRQLAASIDHPEVAGLLALMLLHHARRSARTGPD
                     GSLVPLAEQDRGRWDTVMIAEGVAILQAALARDRLGEFQAQAAIAALHADAPTAGETDW
                     VQIVEWYDELVRLTDSPVVRLNRAVAVGEADGPRAGLAALAALDEALPRHTAVAAYLHE
                     RDGDLETAARLYAEAARKASNLAERDHLTRRAARLTQLRRTG"
     gene            complement(9423..9830)
                     /db_xref="GeneID:91413246"
                     /locus_tag="PET44_RS30120"
                     /old_locus_tag="PET44_30120"
     CDS             complement(9423..9830)
                     /codon_start=1
                     /db_xref="GeneID:91413246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007512669.1"
                     /locus_tag="PET44_RS30120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_30120"
                     /product="YciI family protein"
                     /protein_id="WP_037798881.1"
                     /transl_table=11
                     /translation="MAKYLLLKHYRGAPAAVNDVPMDQWTPEEISAHMRYMQDFADRLE
                     GTGEFVDGQALAPTGTFVRYDGEGRPPVTDGPFAETKDLIAGWMVIDVDSYERAVELAG
                     ELSAAPGAGGKPIHEWLELRPFLTAPPTITE"
     misc_feature    9805..9821
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.71"
                     /tool="antismash"
     misc_feature    complement(9905..9925)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     misc_feature    complement(9988..10003)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.28"
                     /tool="antismash"
     gene            10001..11125
                     /db_xref="GeneID:91413247"
                     /locus_tag="PET44_RS30125"
                     /old_locus_tag="PET44_30125"
     CDS             10001..11125
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91413247"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003959586.1"
                     /locus_tag="PET44_RS30125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_30125"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_271244986.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.4e-29, bitscore:
                     101.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHATVNAATLERVLGHRTRFDARFGQYFDSLAGRFDLPVPSRYVP
                     RCLDLLRDLSMRGGKRLRVVLLYEAARLVTTEEVPGLAEAALSIELLQTHGLVHDDIID
                     DAPLRRCGPSTYYAYRREFPGHGATALGLAVLAGDLAGFLSTQVLLEAEAPVALRQALL
                     GVHTRTAAETVAGQIADLERDAHALPDEEFLHTVTDFKSARYSILAPLTMGLLAAGEDP
                     APHRARLHRYARLVGISEQMRDDCLDLFGPFGEDAGSDAVAGAAPAAADKSTGADIRSG
                     RRTYAVRAVLAAATGADAALVEAALGDPRCPDATLERIREIARAAGVDGRLKAEIRRHA
                     EEAAAEAASWEPYWRAEAVELFRGLPMWNVDRMP"
     gene            complement(11132..11857)
                     /db_xref="GeneID:91413248"
                     /locus_tag="PET44_RS30130"
                     /old_locus_tag="PET44_30130"
     CDS             complement(11132..11857)
                     /codon_start=1
                     /db_xref="GeneID:91413248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020550765.1"
                     /locus_tag="PET44_RS30130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_30130"
                     /product="DUF4386 domain-containing protein"
                     /protein_id="WP_271244987.1"
                     /transl_table=11
                     /translation="MGETRRLAVVAGALFLVTEVAAIGGLALYRPVLDGPGYVVGSGAD
                     TRVFLGAVCELVLALAVMGTGAALYPVLRRRGEAAAVGYVCGRLLEAAVIVVGIVSVLA
                     VVTLRRSAGPSGAADAASLVTAGKALVALHDWTFLLGPNFVLGANTLVLACLLYTSRLV
                     PRAVAVLGLAGGALICASATAVLFGVYEQVSVAGSLAALPVFAWEVTLAVRLLFKGFDE
                     AAGDGAGEGARARVDALAG"
     misc_feature    11917..11935
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.17"
                     /tool="antismash"
     gene            12001..12747
                     /db_xref="GeneID:91413249"
                     /locus_tag="PET44_RS30135"
                     /old_locus_tag="PET44_30135"
     CDS             12001..12747
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91413249"
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010476397.1"
                     /locus_tag="PET44_RS30135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_30135"
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="WP_271244988.1"
                     /transl_table=11
                     /translation="MPADVPAEESRRTPLSRGRVLRAAVAFADGAGIEALSMRRLAQEL
                     GVVPMALYKHVANKEELLDGMVEAVVAGLDPHVPGADWKSAVRRRILGARDALVRHAWA
                     AQVIRSRTSPTPAVLAYLDSVIGMFRAGGFSLDLTHHAMHALGSRVLGLTEELFDAPPS
                     PGPRATATASVSAPAADPAQTAAREAMALRYPHVTELAGAVAHDRSSVVGGRGCDDRFE
                     FEFALDLLLDGFERLHGQGWTSAPRP"
     gene            12780..13400
                     /db_xref="GeneID:91413250"
                     /locus_tag="PET44_RS30140"
                     /old_locus_tag="PET44_30140"
     CDS             12780..13400
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91413250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268533.1"
                     /locus_tag="PET44_RS30140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_30140"
                     /product="nucleoside/nucleotide kinase family protein"
                     /protein_id="WP_271244989.1"
                     /transl_table=11
                     /translation="MEFAELEERARTLAASGGRRILGIAGPPGAGKSTLAARLARALGA
                     ELAVAVPMDGFHLAQAELVRLGREDRKGAPDTFDAAGYAALLRRLRAAPGEGAGAVYAP
                     AFDRALEEPVAGSIRVGPAVRLVITEGNYLLYGAGEWAQVRPLLDEAWFLAPDDAVRVR
                     RLVDRHVRHGRDRAAAEEWVSRSDESNARLVAPGRAGADLVLE"
     gene            13420..14694
                     /db_xref="GeneID:91413251"
                     /locus_tag="PET44_RS30145"
                     /old_locus_tag="PET44_30145"
     CDS             13420..14694
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91413251"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="PET44_RS30145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_30145"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_053065839.1"
                     /sec_met_domain="Pkinase (E-value: 2.3e-45, bitscore:
                     153.6, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAESGALIGGRYRLVELRGRGGMGRVWRGLDERLDREVAVKEIV
                     FPDGVDEERREALLHRFVREARAAARLNDPGIITVHDVVEHEGAPVIVMEYVTGPSLAA
                     QVARGGGMPVRRVAELGVLMVKALRRAHAAGIVHRDLKPDNVLLMDDRVIITDFGIAHV
                     ADATMTLTRTGTLLGTPAYMAPEQLEGGPPTPATDLWSLGATLYCALEGRPPFVAETFS
                     ALCVAIVMQDPPVPGRAGPLAPVLAALLTKDPAGRATAEQALAALEAVAGGAAQREPQP
                     QPQPPPQPQPEQRRRQRLPGSSLRGAGCFALVWLGTLLPWNHIREWHGFQRELLVGATA
                     AVVALANAGLRPRGPAGPGWALFAGLNLALFLVAALIWPVWGLPAVIANGLLVGTVSWS
                     LWWSLSRAGVPAGVRPDGVSERGTR"
     gene            complement(14672..15532)
                     /db_xref="GeneID:91413252"
                     /locus_tag="PET44_RS30150"
                     /old_locus_tag="PET44_30150"
     CDS             complement(14672..15532)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (24-272). E-value:
                     2.8e-26. Score: 84.6. Matches aSDomain:
                     nrpspksdomains_PET44_RS30150_Abhydrolase_1.1"
                     /codon_start=1
                     /db_xref="GeneID:91413252"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018558022.1"
                     /locus_tag="PET44_RS30150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_30150"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_229895266.1"
                     /sec_met_domain="PF00561 (E-value: 2.2e-21, bitscore: 75.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.3e-18, bitscore:
                     67.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLHFFTSYDGTELAYRVTGDGGAPPLVCLPGGPGRAAAYLGDLG
                     GLGAHRTLILPDTRGSGASAMPADLATCRVDRLVADVEALRGHLGLETFDLLGHSAGGS
                     LAQLYAAAHPGRLRRLVLVTPSFASIGLPSDTGAEEVLRSRAAEPWYARALPAYRAVKA
                     ARSFEEAAAHRPAFEPLMYGRWDAAARAHAAADPAQRSLPVSEAFYAGYAPDTEALAAR
                     LARLAAPVLLLAGERDLWPTAAAAARAAGVFPEAELTVLPGAGHYPWLDDAAAFAAAVT
                     GFLAR"
     aSDomain        complement(14717..15460)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PET44_RS30150_Abhydrolase_1.1"
                     /evalue="2.80E-26"
                     /label="PET44_RS30150_Abhydrolase_1.1"
                     /locus_tag="PET44_RS30150"
                     /protein_end="272"
                     /protein_start="24"
                     /score="84.6"
                     /tool="antismash"
                     /translation="PPLVCLPGGPGRAAAYLGDLGGLGAHRTLILPDTRGSGASAMPAD
                     LATCRVDRLVADVEALRGHLGLETFDLLGHSAGGSLAQLYAAAHPGRLRRLVLVTPSFA
                     SIGLPSDTGAEEVLRSRAAEPWYARALPAYRAVKAARSFEEAAAHRPAFEPLMYGRWDA
                     AARAHAAADPAQRSLPVSEAFYAGYAPDTEALAARLARLAAPVLLLAGERDLWPTAAAA
                     ARAAGVFPEAELTVLPGAGHYPWLDD"
     CDS_motif       complement(15203..15250)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PET44_RS30150_0001"
                     /evalue="1.80E-04"
                     /label="NRPS-te1"
                     /locus_tag="PET44_RS30150"
                     /protein_end="110"
                     /protein_start="94"
                     /score="14.1"
                     /tool="antismash"
                     /translation="DLLGHSAGGSLAQLYA"
     gene            15628..16590
                     /db_xref="GeneID:91413253"
                     /locus_tag="PET44_RS30155"
                     /old_locus_tag="PET44_30155"
     CDS             15628..16590
                     /codon_start=1
                     /db_xref="GeneID:91413253"
                     /inference="COORDINATES: protein motif:HMM:NF024248.4"
                     /locus_tag="PET44_RS30155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_30155"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_047961198.1"
                     /transl_table=11
                     /translation="MSVEIRLTAAEVARVRFAVSPLAETVLGVRAALTATGQAVHHRWL
                     AEARDVLRDDPELPLLRNLLGHCLPSFLLPVPRERLPSLDEELADLCATDPAYFAAECA
                     AGAGARAAGRLPAAEVALPRLAGALRRCHDRLVAPHWGRMRAVLDADVGRRAVALVDGG
                     VEGLFTQLHRDIAWREGELVVGGRRRAGAAPCAVEASGHGLVLLPSVFAWPDVLVDRSP
                     VTAASIRYPALGVGLLWEPDRPTRDGLAAVLGATRAALLAALAEPLTTPALAARLGVTP
                     SAVSQHLGALRGAGLVSTRRSGRTALHLRTARAVDLLTG"
     gene            16736..17416
                     /db_xref="GeneID:91413254"
                     /locus_tag="PET44_RS30160"
                     /old_locus_tag="PET44_30160"
     CDS             16736..17416
                     /codon_start=1
                     /db_xref="GeneID:91413254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982876.1"
                     /locus_tag="PET44_RS30160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_30160"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_047960821.1"
                     /transl_table=11
                     /translation="MARPAPTPARSRRRRRIAVAGAALCAGLFVLLAVLVTARHGAPYP
                     LDSAAHRWSVRHRPAVAVAFARAVTSTGSGPFPYACAAAAGAIAGRGTRERLWGAAAAL
                     LFLGFAQAVRFGVLHLIGRPRPPLAEWATVAHDHSFPSGHTTASALAAGLLAWALLRRA
                     GPAAAAIPCVILAGWAVAVGLTRIYLGVHWPTDVLAGWLYALTWFAVGYAVFPYVLRMF
                     TDTD"
     gene            17443..18231
                     /db_xref="GeneID:91413255"
                     /locus_tag="PET44_RS30165"
                     /old_locus_tag="PET44_30165"
     CDS             17443..18231
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91413255"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657070.1"
                     /locus_tag="PET44_RS30165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_30165"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_037798892.1"
                     /transl_table=11
                     /translation="MWAAGEAYEPYVGRWSRLVAAEFVRRLAAAPGGSWRDIGCGTGAV
                     ARAVLAAAAPRRVIGVDPAESYVRHARRHLAGPRADFVVGDALALPFPDGRATAAVSGL
                     VLNFVPDPARAAAEMVRVVGPGGTVAVYLWDYGEGGMRAIRAFWDAARALDRRAEALDE
                     AVRFPLAGRKPLRELLTGAGLAGVETGEITVPTRFRDFDDYWGPFLGGQGPAPAYVASL
                     PEDHRAELRERLRATLPRACDGSIRLTARAWTAWGARPPG"
     gene            complement(18329..18544)
                     /db_xref="GeneID:91413256"
                     /locus_tag="PET44_RS30170"
                     /old_locus_tag="PET44_30170"
     CDS             complement(18329..18544)
                     /codon_start=1
                     /db_xref="GeneID:91413256"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PET44_RS30170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PET44_30170"
                     /product="hypothetical protein"
                     /protein_id="WP_037798893.1"
                     /transl_table=11
                     /translation="MYEMRAESIADRCQLLWHVIAKDTTFSTLCGSLLNPDQTPPPEAD
                     PAAERYCAPCMTAFSRAVHAFGTPSE"
     gene            18695..18988
                     /db_xref="GeneID:91413257"
                     /locus_tag="PET44_RS30175"
                     /old_locus_tag="PET44_30175"
     CDS             18695..18988
                     /codon_start=1
                     /db_xref="GeneID:91413257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014158031.1"
                     /locus_tag="PET44_RS30175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_30175"
                     /product="hypothetical protein"
                     /protein_id="WP_037798895.1"
                     /transl_table=11
                     /translation="MAWASWTTTGVFPGAGGVRTEEVGIISGDLTVHTTWTGAQAQVAV
                     QYSSSSDWFTLSGSPVECVSEPESRDLHQAVVEAVRGGGGSGVPPHWATFAA"
     gene            complement(19265..20062)
                     /db_xref="GeneID:91413258"
                     /locus_tag="PET44_RS30180"
                     /old_locus_tag="PET44_30180"
     CDS             complement(19265..20062)
                     /EC_number="1.1.1.30"
                     /GO_function="GO:0003858 - 3-hydroxybutyrate dehydrogenase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (24-177). E-value: 6.3e-07.
                     Score: 21.4. Matches aSDomain:
                     nrpspksdomains_PET44_RS30180_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GeneID:91413258"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004979647.1"
                     /locus_tag="PET44_RS30180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_30180"
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="WP_047960823.1"
                     /transl_table=11
                     /translation="MTSKLPPALPLPAPGPAGVDLRGRVALVTGGGSGIGRACAVALAA
                     AGAAVHVVDVDAPSAASVARLVRGRAHVTDLADPAAIEELPAHVDILVNSAGLQHVAPI
                     TQFPVERFALIQRVMVTAPFLLLRRVLPHMYASGWGRVVNISSVHGLRASAYKSAYVAA
                     KHGLEGLSKVTALEGAPYGVTSNCVSPGYVRTPLVEGQIADQAAAHGIGAADVVADVLL
                     TRSAIKRLIEPEEVAAAALWLCGPHTGYITGISLPLDGGWAAN"
     aSDomain        complement(19532..19990)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PET44_RS30180_PKS_KR.1"
                     /evalue="6.30E-07"
                     /label="PET44_RS30180_PKS_KR.1"
                     /locus_tag="PET44_RS30180"
                     /protein_end="177"
                     /protein_start="24"
                     /score="21.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VALVTGGGSGIGRACAVALAAAGAAVHVVDVDAPSAASVARLVRG
                     RAHVTDLADPAAIEELPAHVDILVNSAGLQHVAPITQFPVERFALIQRVMVTAPFLLLR
                     RVLPHMYASGWGRVVNISSVHGLRASAYKSAYVAAKHGLEGLSKVTALE"
     CDS_motif       complement(19844..19984)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PET44_RS30180_0001"
                     /evalue="2.50E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="PET44_RS30180"
                     /protein_end="73"
                     /protein_start="26"
                     /score="13.7"
                     /tool="antismash"
                     /translation="LVTGGGSGIGRACAVALAAAGAAVHVVDVDAPSAASVARLVRGRA
                     HV"
     gene            20257..20754
                     /db_xref="GeneID:91413259"
                     /locus_tag="PET44_RS30185"
                     /old_locus_tag="PET44_30185"
     CDS             20257..20754
                     /codon_start=1
                     /db_xref="GeneID:91413259"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PET44_RS30185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PET44_30185"
                     /product="hypothetical protein"
                     /protein_id="WP_037798899.1"
                     /transl_table=11
                     /translation="MTPDIDTAELVAAVNTVERARHLLGEARDELGGAGVSRDQEWTAA
                     GSPVQTLQGADDMHRGSGQFLDDLALALGYAAAGLAEQALRQRERAGQGFLGLSGADRM
                     ARPLPAPTVEALELLRGLDLLTPEFRERITGALEAEAATYPDPAPQRPLRLGTSGLTPT
                     AG"
     gene            complement(20764..21012)
                     /db_xref="GeneID:91413260"
                     /locus_tag="PET44_RS30190"
                     /old_locus_tag="PET44_30190"
     CDS             complement(20764..21012)
                     /codon_start=1
                     /db_xref="GeneID:91413260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018100553.1"
                     /locus_tag="PET44_RS30190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_30190"
                     /product="DUF6296 family protein"
                     /protein_id="WP_037798900.1"
                     /transl_table=11
                     /translation="MSEDHEDRYELVFGSGEPESEGEDLVVVSRTAQKGPGGHPVYADS
                     TGIVRAEISDQGEVRMLPSGGQQSLAQPTRARRPGSP"
ORIGIN
        1 gtgggcatcc gcgcgtgggc catgtcgctg agcggcagga cgcaggcggc cgtgtcggag
       61 aacgtgacca ccgagacgcg ggcgatctct ccggtggtcg ggtcgtccag gatcgcccgc
      121 tgcatggcgg ggagcgcggt gttcatcgcc gccatcgggc cgcccgacat cgacccggac
      181 acgtcgatga gaaggcagac ggggaatacc gcgggacgtt ccgattgcga gaactgggac
      241 acgggaactc caatttcgtg cggacgcgcg agatgggcat ggaagtgacc ggaagggaaa
      301 gggaggggaa tgccgggcaa tcggcatgag gaatggagcg gctcgcggaa cattccgcgc
      361 ctcgcggctc cgcattcccc tgatcgcgtc cctccactat gcacgatcgg ggagggtgat
      421 cgagcgctgt tttccgtatc gtgaggcaat tcccggagga cgcccggact gcgcccggat
      481 cgcgcccggc ccgtgcccgg gccgggcgcc cggcggcttc agtccgcggg cgcgccgacc
      541 cgcgcgcagt acgggtccaa cgcgctgtcg agccagcgcc ggcccgcact gtcgtcgagg
      601 tcgatgccgc ccgggacggg gcgcaggacc tcgttcccgt cctcgcggac cagcgggccg
      661 aagcggtcgc cgaagagcac cgcggtgggc tccggatggt tctgccggga ggtccagatc
      721 agcccctgcg cccagtcggc ctgcccgcgc agccagtggc cccagcgccg ggtgaagggg
      781 tagtcggggg attcggactg gatgagccag gtgccctggt tgaccgcgct cgtcgcgcgg
      841 cggtcgagca gcgagagcag cgtgacgtcg gtcaacagct ccagccggga caggcgccgg
      901 tcctcgatgg cgctgtacga gaccacgcgc ggctccccgt cgtcgaccgg gagctccttc
      961 agcaggctct cgacgagggc ggtctcggcg ctgggggcca ggtagaggta ggagtactcg
     1021 tcgttggggg tgctgtcgaa gcgggtgccg ccgaagtggt ggtcgaccac ggtcgcgttg
     1081 aagtcggccg ccgatcggct cttgcggtgt acccggtaga gcgtcgtccc ggcgggccag
     1141 accacctggt gcggtgtgcc cgcgagcttg ccggggagtt tcgcaggacg tgccacgtca
     1201 gtccccctcg cccacggccc gggccgcggc catcagttcg tcgtccggga cgctgcccag
     1261 gacctccgcc ggcggggccg cgagccagtg gttgggcccc agccaccagt ccgcggcgcc
     1321 ccacgggtcc ttggaggccc tgagcacctc gttgatggcc aggaccagcg gcaccgggac
     1381 gcagtcctcc tggaactgga acgacggcag ccgcacctct ccgcccttcc gggtcagccg
     1441 gatcaggtgc ggatgccggg gatcctgccg cagcacgtcc ctgacctggg cctcggagag
     1501 cgaggaggcg gagagcagcc gctcgcggat gcggtcccac gaggagggcg ccgcggggcc
     1561 cgccggctcg gcccggtggt gcgaaggccg ggcgcccgag gaccggacgg gcacgtggtg
     1621 gccgtgccgc gtggccatcc ggcggatgag cccgggcgcc gccgaccggt cgggcgccat
     1681 ggtcgagcgc cacctgcgca gggcggggtc gtcggccggg agccggccgc gcacatgggc
     1741 cgccaccgcc tcgccgacgg ccctgagccc gtcgtcgtcc gagacgttcg cgaacagtcc
     1801 cagcaaacga tcgagctgaa tacgatcagc ttcggtcaaa cgttcgcgta tatcgtcagg
     1861 attcgattcg aggtcggcca gaatcgaaag atcaatatcg tccatgcatc gttccccctc
     1921 acgcgcctgc cagtacgttc cgggacggca aagcggtcgc cacgagcgta ctggaaaaac
     1981 cggatcggtc caccgagtgc gccatccata ttgccaggca cgtaccccgc cgggcagaat
     2041 cgcagcgtcc ccgccacgcc atcgtgaagg caaggggcaa agaaggggat acggggaccg
     2101 cgacggtccc cggggggagt cggggatcgc ggaaccgtga acttccggtg ccgcgggaaa
     2161 acaggctgac ggcggaccgg catccgctcc ggatcgtgaa ttccggccgc cggaccgggc
     2221 cgtcgcggaa gggcaacggg gggatcatgg acgcgtcagg gagcgacgac atccgggcgc
     2281 tggagcggga gatcgccgcg ctgcgcgagc gggcccgggt cctgcacccc ggtggtcagg
     2341 agcgctggaa caccgaagcc gacctcgccg aactcctgtt cgtccacgcc ctggaggtcg
     2401 cctcggccgg ggcggccacc gccgccgggg cgcccccgct cccggagggt ctcgccgagg
     2461 cccgcgccct gctcgaccgg ctgctgtccc agcgccgccc cggcagcgcc tcgtaccact
     2521 gggcctgcct gctcgcggcc cgcgccgccc ggggcgaggc cgagctgacc ggcgatccgg
     2581 acgcccggga cgcggcgatc gagcggttcg agaccgcgat cgcgccgctg cccccgtacg
     2641 ggcccgacac cttcccgccg ctgccgggcg aacccgagtg gtggacgccc gccctggccg
     2701 tggacgcccg gtgcgagctg ggcctcgccc tgtacaaccg cagccgcgag ctcaccggcg
     2761 ggagccggtc ccgggacctg gaccgcatcg tcacccttct cacccccgtg gtggacggcc
     2821 ccgaggccgg gctcgcccag gacctccagg tgacactggc ctgtctggga ctcgccctcg
     2881 ccgaccgctc gcgcgccccc ggccaccgcg gcccggaccg gccggccgac cgtaccgagg
     2941 cgatcggcag gctccgcgcc gcccgcgaga ccccctcgga ggacgaggtg ccgggagccg
     3001 tcccgttcca gctggcgctg ctcctcttct gcgagcacga cgacggctgc ggcggttccg
     3061 agggcgccga cggccgcgga ccgtccgccc ggcggaccgg ggaactcgac gaagcgctcg
     3121 ccctgctgtg gccgctgacc ctggatccgt cggccgacgg cggcgaggcg acggaactcg
     3181 ccacgatgac cgcccggcac ctgtacgaac acgacggcgg tccggccgcc gagacggccc
     3241 tgatcgaatg gcaccgcagg gcgatcgacc accccggcac ccagcgccgc caagtacgcg
     3301 ccaaccggac cgacttggcg ctgctgctca tcgaccgggc cgagcgcggc gccacggcgc
     3361 ccgcccccgg gacgcccgcc cccgggacgc ccgcccccgg gacgcccgcc cccgggacgc
     3421 ccgcccccgg gacgcccagc cgctcggacg atctcggcga agccgcccgg catctcgaac
     3481 tcgccctcga tgacctcgcc ttgaaggagc gggccccgtc cgtacggctg cgggcggagg
     3541 acgatccgcc cgagaccgac gcggaccgag ccgaggagcg gctcaacatg ctcctcgggc
     3601 tggtcacgct gctcagcatg ctcctgcccg agagctccga cgacgcccgg ctcgaccgcc
     3661 tgatccgccg cgggcaggag ctgatcgagg tcattcccga cgccgacacc gagcgcggcg
     3721 gcgcctgcct ccggctcgcc ctcgccctct tcgagcggac ctcccggcgc accctgccgc
     3781 agctgcccgc cctgctgatg cgcgcgatga ccccggaccg ggccgacccg gggatctccc
     3841 tcgtcgccaa cgtcccgggg gtacgggagg acaacgagct ggcgatcgcc ctgctgcgga
     3901 ccggagtcgg cctctacgga tacgaggacg agctctacga ggccgccgcc atcgcgctgg
     3961 cggtgagcct gctcatcggc tacacggtcc ggctgcccga gcgggacacc gcgctgatcc
     4021 gggatgcggt gcactggttc cgcatcgtcc tcgaccgggt gcccgagggc ggcgagctcc
     4081 acagcccgga cctggaggac ctgttcatcg gggcgctgct caacagcgtc tggaccagcg
     4141 agccgttcgt acgggcgcag accggctcgt ggcgcgacgg agaggggatc cccgacgtct
     4201 cccgcaacca gagcgtcgag gacgacctcc agagcctcag gcacctgctg gagacggccg
     4261 tgcgccgccg cgaacagccc gtgcccgtct acgagatggt gctcctgctg atcaccttca
     4321 tgcgcggcaa gggcgagctg gacgacgcgg aggcgcggca ctggcgcgac cggctccggc
     4381 gggcatcggc ctacaccgac ccggccgagg aatcgctgaa gggcttcctg ctgctggcgg
     4441 ccggggcgtt cgggtacgag ctggcgcggc gcggagccgc cggcccggcc gaactcgccg
     4501 aggccgacag gctgttgcgc gagggcgcgc gccacatgcc gccgggcagc gacttcgcgg
     4561 agtgggccga ggggctgcgg gcgaccgggc ccgccacgct gatccagcag ctgctgggcg
     4621 tgttcatggg cggcgcctcg gcccccgggg cggcagcggc gggagccccc ggcgcggccc
     4681 gtcgcccggc ggacgatgcc gtacgcgctc ccggccccgc gcgaccgccg ggctccgccc
     4741 gcccgccggg tcccgtccgg cccccggccc ggtcggcgcc cgccgaggcg gaggacatcc
     4801 cgctgtcggc cgcggcggtc ctgcccggag acggcagccc gtaccccttc accgaacccg
     4861 tgggccgcgt cctcgaaatc gtcaccgggc cggccgggcc ggccgggccg gccgagcagc
     4921 ggtccgcccc cgtcatggcc gcgcacgccc tggcgctgca ccggcggtgg ctgcacgaga
     4981 gcgagatcgc cgacctcacc gacgccgtca ccctcacccg gcgggcgatc gccgccgcgg
     5041 agggcgccga cggccccctg gccgaccggc tgtcgctgct gctcgcgggc atgctgcgcg
     5101 accggtacct gctgatcggc gaccggatgg acctccaggc cgcccggacg gcgtacgagc
     5161 ggctgcgcga ccggtccgac ccgcgcgccc cgcaccccga gctcgccatg ctgctggcgc
     5221 ggcccggcgc cgaggggcag cccgacctcg cggcgctgct gcggcccgcc cgcccggcgg
     5281 cccccggcgc cttctccgcc gagctcctcg cggccgcagc cctgaccgga ctgctcgccg
     5341 cccgcgagga cggcgccgcc gaccgggccg cggcggaact cgccgaagcc ggcgaggcgc
     5401 tgcccgccga ccaccccctg ctgcccgccg tactcagcga atcgggcctc ttccgcgcca
     5461 cccgggcggc ccgcgccgac gggctcgcgg ccctgcgcga ggccgtcgag gacgtcgtac
     5521 gggcggccgc cctctgcccg cccggcagcg cgcaccgggc gccgctgctg ctccgcgcgg
     5581 ccgccgtgct gtgcgcgcac agcgacgcgc tggacgcggc cgacccggcc ggccccgccg
     5641 cccccggctc ccgtgcgagc tccctcgacc gcggcatcgg cctgctgtcc ggcgcggtcg
     5701 acgaggcggg gccgagcttc cacggggccc gggcccgctg ccggtacggg ctggggagcc
     5761 tgctgctcac ccgcttccgg cgcagccgcg accgggccga cctcgaccgg gccgtcggcc
     5821 tcctccggga cgcccgcacg gccgtcctct cccgtccggg cgacccgttc acggtgctcc
     5881 tcacccgggc cctggccgag gcgctgcggg cccacggtcc cgaggacccg gaccaccgcg
     5941 cgcagtcccg ggaggcggcc aagtccgtcc tcgcggcgca cggccgggcg gtgctgctcc
     6001 agaccggcac cgagaccgcc ctcgactccg cccgcgcggc cggctccgac atgatgcgcc
     6061 tggtcgagtg gtgcctcacg gacggccgta cggaagaggc gctggaggcc ctggaactgg
     6121 ggcgcggact ggtgctgaac gcggcgaccg tcgccgcctc cgtacccgaa ctgctggagc
     6181 gggagggccg gccggagctg gcgcaggcgt ggcgacgggc cgatcccggc cgggtgcccg
     6241 gtacacctgc cgacggcccc gtggtcatcc ccgacgggct gcggctgctc gtgctccagg
     6301 cgctggaggg cggcccggcg gaacgccgca tcctctccgc gcccacaccg gccgagatcg
     6361 gccgggcgct gcggacggtc ggtcacgacg cgctggtcca cctgatcccg ggccgggacg
     6421 ggtccggcga cgccctgatc gtgaccgcga ccggagcggt ggagcggctg cggcttccgg
     6481 ggctgtgcgt caccgacgac ggcccggcgg ccgcgtacgg cgaggccctc caggagttcg
     6541 ccgcggccac ccgggagccg gtcgtgctgc cgggggagga cgacccggcc gtgatgtggg
     6601 agctctaccg gcgcggccgc aagcgcctcg gccgggcctc ggaccggtgg cgcggcgccc
     6661 tggaaccgct ctgctcctgg gccggcgaag tggcgatggc cgcggtgatc gagcacgtcg
     6721 gggcggggcg gcggcaccgg ccggcccggc tggtgctgtc cccggtgggc atgctcggga
     6781 tggtcccctg gcacgccgcg cgactgccgg gcgcgcccgg ggtgtccgca gagcccggcg
     6841 gcggctacgc ctgcggccgg gcggtgatct cgtactgctc cacgtcccgc cagctggtgg
     6901 aggtggcggc ccgggcgcgg ctgccgtgga acggcgctca ggcggtggtc gccgacccgg
     6961 gcggcacccc ggccatgcac gaggaggccc ggctgatcgc ggcgctgtac ccgggggcca
     7021 ccgtcgtcgg gccggtcgac gacgtgcccg agccgggcgg ccccgggagc cgcccgccgt
     7081 cccggccggc cacggcggcg gcggtggcgc cgctgctgcc gggccgcggc gggtccagcg
     7141 ttgccgtctg ccacgtcaac tgccacgcca ccgcccgggc gacgccctcc gcgtccagcc
     7201 tcgacctgca ccccgccgcg cctgtgccgc aggtgctgac cctggcggag atccaggccc
     7261 tcgcccacgg ccgcgacccg tcggcgcccg gcggtctgct ggtcctcgcc aattgcacca
     7321 gcgacctgac cctggccgac tacgacgagg cgctgacgct gtcgacggcg ttcctcacgg
     7381 cgggagccgc ctcggtggtc ggctccctct gggcgatcgc cgacgacatc cgcacctcga
     7441 tggtgatgta cgtgttccac cactacctca ccggccgcgg actgcccggg cacccggagg
     7501 cggtgggctc gccggccgac gcgctgcgcg ccgcgcagct ctggatgctc gacccgcacc
     7561 ggatcgtccc gcccgcgctg tccgccgtaa tggaagagcg tcccggactc gacctcgacg
     7621 ccccgcacat ctgggccgca tttacccacc acgggcactg acgtcactcc attaacgtat
     7681 tttgtcatgg cggtcgattt cagccacggt ttctgccacg ataatggcga gtaaagcctc
     7741 aaaggcgatc gggaaaaacc caggggggga aatgcggtga ggtacgatca agcggccatg
     7801 gtggcggccc tgaaattcgc ccacagcaat ctcgacggac tgaaggtcaa ggagctggtc
     7861 gacaagaagg gaatcgagtg gtacatcaat cactgcgccg cgctcgcggc gacgaccggt
     7921 gtggcgtcag ggatgggggg cccagccacg atggtgctgg gcgtcccggc ggacatggcc
     7981 aacaccatcg cgcagcagtt ccgcgtcacg atggcggtga tctaccacaa gaccgggagc
     8041 tattcgcttt cgttcgatga attcatgaag atcgtggccg tgtcgctcgg ggtggaggtc
     8101 ggaacccagg tcgtcgtgcg ggtggcggcg gaaatcttca aacgactcac ggcgaagatc
     8161 gcggggaagt tcatccccct cctcggcggc gtcattggcg ggggcctgaa ttacggcttc
     8221 atcaaggctc agggaaaggc catgctcgcg ctggatttcg acaagttatc ccgttcggcg
     8281 tagctgggtg aggcgggcgg cccggcgcgt cagatggtcg cgctcggcga ggttggatgc
     8341 cttccgagcc gcctcggcgt acagccgggc cgccgtctcc aggtcgccgt cccgctcgtg
     8401 gaggtacgcc gccaccgcgg tgtggcgggg cagcgcctcg tccagcgccg cgagcgccgc
     8461 cagcccggcg cgcggaccgt cggcctcgcc gacggccacc gcgcggttga gccggacgac
     8521 cgggctgtcc gtcaggcgta cgagctcgtc gtaccactcg acgatctgca cccagtcggt
     8581 ctccccggcg gtgggcgcgt cggcgtgcag tgccgcgatg gcggcctgag cctggaactc
     8641 gcccagccgg tcgcgggcca gggccgcctg caggatcgcg acgccctcgg cgatcatcac
     8701 ggtgtcccag cggccgcggt cctgctcggc gagcggtacg aggctgccgt cgggcccggt
     8761 ccgggcggag cgccgggcat ggtggagcag catgagggcg agcagcccgg ccacctcggg
     8821 atggtcgatc gaggccgcga gctgccgggt gagccggatg gcctcggcgg cgaggtcgac
     8881 gtcgccggag tagccctcgt tgaagaccag gtagaggacg cgcagcacgg tggcgacatc
     8941 gccgggctgg tcgaaccgca ccccggagac ggtgcgcttg gcccggctga tgcgctgcgc
     9001 catggtcgcc tcgggcacca ggtaggcctg ggcgatctgg cgggtggtca gcccgcccac
     9061 ggcgcgcagc gtgagcgcga ccgcggacga gggcgtcagc gccgggtggg cgcacaggaa
     9121 gtacagctgg agcgtgtcgt ccacaccggg cgcgggtccc ggcgcgggct cctcctcgac
     9181 gaggtcctcg cgccggcgcc gggcggtgtc cgaccgggcc gcgtcgaggt accggcgcca
     9241 ggccacggtg accagccagc ccttcggctc ccgcggcatg tcggccggcc agacgcggac
     9301 cgcctcgacc agcgcctcct gcagggcgtc ctcggccgcc gcgaagtcgg ctccgcggcg
     9361 gacgaggatc ccgagcacgc tcggggtgag gctcctgagc aaggcctcgt tcatcggtga
     9421 ggtcactccg tgatggtggg cggcgcggtc aggaacgggc gcagttcgag ccactcgtgg
     9481 atcggcttcc cgcccgcccc gggggcggcg gacagctctc cggccagctc gacggcgcgc
     9541 tcgtaactgt cgacgtcgat caccatccag ccggcgatga ggtccttggt ctcggcgaac
     9601 gggccgtcgg tgacgggcgg gcggccctcg ccgtcgtacc ggacgaaggt ccccgtgggg
     9661 gcgagcgcct gaccgtcgac gaactcgccg gtcccctcca gccggtccgc gaagtcctgc
     9721 atgtaccgca tgtgggccga gatctcctcc ggcgtccact ggtccatggg gacgtcgttg
     9781 accgccgcgg gggcgccccg gtagtgcttg agaagcaggt acttggccat ggtggttctc
     9841 ctcgtacggg tgcggcccat tctggccgcg ttcaccccgg ggacggagcg ggccacgggt
     9901 tctcgacatc gccggcggaa ttttttcgcg gcatcccgcc agcccgcgca ccccacgcct
     9961 gccggcccgg cccccggccc ggtcgccgat actgatctcc atgcacgcca cggtcaacgc
    10021 cgccaccctg gaacgcgtcc tcgggcaccg gacccgcttc gacgcccggt tcgggcagta
    10081 cttcgacagc ctcgccgggc gcttcgacct gccggtgccg agccggtacg tcccccggtg
    10141 cctggacctc ctgcgggacc tctcgatgcg cggcggcaag cggctgcggg tcgtcctgct
    10201 gtacgaggcg gcccggctgg tcaccaccga ggaggtgccg gggctcgcgg aggccgccct
    10261 gagcatcgaa ctgctccaga cccacgggct cgtccacgac gacatcatcg acgacgcgcc
    10321 cctgcgccgc tgcggcccct ccacgtacta cgcctaccgc cgggagttcc ccggccacgg
    10381 ggccaccgcc ctcgggctcg cggtgctcgc cggtgacctc gccgggttcc tctccacgca
    10441 ggtcctgctg gaggccgagg cgcccgtcgc gctccgccag gccctgctcg gcgtacacac
    10501 gcgcaccgcc gcggagaccg tggccgggca gatcgccgac ctggagcggg acgcccacgc
    10561 gctgcccgac gaggaattcc tgcacaccgt caccgacttc aagagcgcgc ggtactcgat
    10621 cctcgcgccg ctgaccatgg gtctgctggc ggcgggcgag gatccggcgc cgcaccgcgc
    10681 ccggctgcac cggtacgcca ggctggtggg catcagcgag cagatgcgcg acgactgcct
    10741 cgacctcttc ggcccgttcg gcgaggacgc gggctcggac gcggtcgcgg gcgcggctcc
    10801 cgcggccgcg gacaagtcca ccggggccga catccgctcc ggccgccgca cctacgccgt
    10861 ccgcgcggtc ctggccgccg cgaccggggc cgacgccgcc ctcgtcgaag ccgcgctggg
    10921 cgatccccgc tgcccggacg ccaccctgga acggatccgg gagatcgccc gcgccgccgg
    10981 agtggacggc cggctgaagg cggagatccg gcgccacgcg gaggaggcgg ccgccgaggc
    11041 cgcgtcctgg gagccgtact ggcgggcgga ggccgtggag ctcttccggg gcctgccgat
    11101 gtggaacgtg gaccggatgc cctgagcgcc ctcacccggc gagggcgtcc acgcgggcgc
    11161 gggcaccctc accggcgccg tcaccggccg cctcgtcgaa gcccttgaac agcagccgga
    11221 ccgccagggt cacctcccag gcgaagacgg gcagggccgc gagcgaaccc gccacggaga
    11281 cctgctcgta gaccccgaac agcacggcgg tcgccgaggc gcagatcagc gcgccgccgg
    11341 ccagcccgag cacggcgacg gcccgcggca ccagccgcga ggtgtacagc aggcaggcca
    11401 gtaccagggt gttggccccg aggacgaagt tgggcccgag caggaacgtc cagtcgtgca
    11461 gcgccaccag ggccttcccg gccgtgacga gggaggcggc gtcggcggcg cccgacgggc
    11521 cggcggaccg tctcagcgtc acgaccgcca gcacgctgac gatgccgacc acgatgacgg
    11581 cggcctccag caggcgcccg cagacatagc cgacggcggc cgcttcgccg cgccgccgca
    11641 ggaccgggta cagcgcggcc ccggtgccca tgaccgccag cgcgagcacg agttcgcaca
    11701 ccgcccccag gaacacccgg gtgtcggcgc cggatccgac gacgtagccg gggccgtcca
    11761 gaacggggcg gtagagcgcg agcccgccga tcgccgcgac ctccgtgacg aggaacaacg
    11821 cacccgcgac gaccgcgagc ctcctggttt cacccatgcg gaacagcccc tccctcgatg
    11881 ggtgtacggc gtacacccga catctggcgc tcacggtagg tgtacgccgt acactcgtca
    11941 aggcgggatg ccgatccacg cccgcccgcc gggcggaagc gacgaccagg gagaaccgac
    12001 atgccggccg acgtgccagc cgaggagtca cgccggaccc ccttgagccg gggccgggtg
    12061 ctgcgcgccg ccgtcgcctt cgccgacggc gccgggatcg aggcgctgag catgcgcagg
    12121 ctcgcccagg aactgggcgt cgtgccgatg gcgctctaca agcacgtggc caacaaggag
    12181 gaactcctcg acggcatggt ggaggccgtc gtcgcgggac tcgaccccca tgtgccggga
    12241 gcggactgga agagcgcggt ccgccgccgg atcctcgggg cccgcgacgc cctcgtgcgg
    12301 cacgcctggg cggcacaggt gatccgctcg cgcaccagcc cgacaccggc cgtgctcgcg
    12361 tacctggact ccgtgatcgg gatgttccgg gccggtggct tctcgctcga cctcacccac
    12421 cacgcgatgc acgccctcgg cagccgggtg ctgggcctca ccgaggaact gttcgacgcc
    12481 ccgccgagcc ccggaccacg agcgacggcg acggcgtcgg tgtcggcgcc ggcagcggac
    12541 ccggcgcaga cggccgcgcg cgaggcgatg gccctgcggt acccccatgt caccgagctg
    12601 gccggggcgg tggcccatga ccggagttcc gtcgtggggg gccggggctg cgacgaccgg
    12661 ttcgagttcg agttcgcgct ggacctcctc ctcgacggat tcgaacgcct ccacgggcag
    12721 ggctggacgt cggccccccg tccgtgacgc ggatccgcac ggtgccgcag gatgggggca
    12781 tggagttcgc ggaactggag gagcgggcgc gtacgctcgc ggcgtcgggc ggcaggcgga
    12841 tcctcgggat cgccggaccg cccggggcgg gaaagtcgac actggccgcg cgcctcgccc
    12901 gggccctcgg ggccgaactg gccgtcgccg taccgatgga cgggttccac ctcgcgcagg
    12961 ccgagctcgt ccggctcggc cgggaggacc gcaagggcgc gcccgacacc ttcgacgccg
    13021 ccgggtacgc ggcgctgctg cggcggctgc gcgccgcccc cggggagggg gccggggcgg
    13081 tctacgcccc ggccttcgac cgggccctgg aagagccggt cgccgggagc atccgggtcg
    13141 gcccggccgt acgtctggtg atcaccgagg gcaactacct gctgtacggg gcgggggagt
    13201 gggcgcaggt acgcccgctc ctcgacgagg cttggttcct cgcccccgac gacgcggtcc
    13261 gcgtccggcg gctcgtcgac cgccacgtcc gtcacgggcg ggaccgggcg gccgccgagg
    13321 agtgggtgtc ccgctcggac gagtcgaacg cccggctggt cgccccgggc cgggcgggag
    13381 cggacctggt gctggaatga ggcccgttag ggttgccccg tgacagcgga gagcggagcc
    13441 ctgatcggcg ggcggtaccg actggttgag ctccggggcc ggggcggcat ggggcgcgtc
    13501 tggcggggcc tggacgagcg gctggaccgt gaggtcgccg tcaaggagat cgtgttcccg
    13561 gacggcgtcg acgaggaacg gcgcgaggcc ttgctccacc ggttcgtgcg cgaggccagg
    13621 gcggcggcgc ggctcaacga ccccgggatc atcacggtgc acgacgtggt cgagcacgag
    13681 ggcgctcccg tcatcgtcat ggagtacgtg accggcccat cgctcgcggc ccaagtggcg
    13741 cgcggcgggg ggatgccggt gcggcgcgtc gccgagctgg gcgtcctgat ggtgaaggcg
    13801 ctccggcggg cgcacgccgc gggcatcgtc caccgcgacc tcaagccgga caacgtgctg
    13861 ctcatggacg accgggtgat catcacggac ttcgggatcg cccacgtggc ggacgccacg
    13921 atgaccctca cccgcaccgg aacccttctc ggcacgcccg cctacatggc gcccgagcag
    13981 ctggagggcg ggcctccgac gcccgccacc gatctctggt cgctcggcgc cacgctgtac
    14041 tgcgcgctgg aggggcggcc gccgttcgtc gccgagacct tctccgccct gtgcgtcgcc
    14101 atcgtcatgc aggaccctcc ggtccccggg cgggccggcc cgctggcgcc cgtactggcc
    14161 gcgctcctga cgaaggaccc ggccgggcgg gccaccgcgg agcaggccct ggccgccctg
    14221 gaggccgtcg ccgggggcgc cgcgcagcgg gagccgcaac cgcaaccgca gcccccaccg
    14281 cagccccaac cggagcagcg gcgccggcag cggctcccgg ggtcgtcgct gcgcggcgcg
    14341 ggctgcttcg cactggtctg gctgggcacc ctgctgccgt ggaaccacat ccgcgaatgg
    14401 cacggattcc agcgggagtt gctggtcggc gcgacggccg cggtggtggc cctggcgaac
    14461 gcgggcctgc ggccccgggg gccggccgga ccggggtggg cgctgttcgc cgggctgaac
    14521 ctcgcactgt tcctggtggc ggccctgatc tggcccgtct gggggctccc cgccgtcatc
    14581 gccaacgggc tgctcgtggg caccgtctcc tggtcgctgt ggtggtcgct ctcccgcgcc
    14641 ggggtgcccg ccggggtccg ccccgacggc gtcagcgagc gaggaacccg gtgacggcgg
    14701 cggcgaaggc cgccgcgtcg tccagccacg gatagtggcc cgctcccggc agtacggtca
    14761 gctccgcttc cgggaagaca ccggcggccc gcgcggccgc ggccgccgtc ggccagaggt
    14821 cacgctcacc ggccagcagc agcaccggcg ccgcgagccg ggcgagccgg gccgccaggg
    14881 cctcggtgtc gggggcgtac ccggcgtaga aggcctcgct gaccggcagc gaacgctggg
    14941 ccggatcggc ggcggcgtgc gcccgggcgg cggcgtccca ccgcccgtac atcagcggct
    15001 cgaaggcggg ccggtgcgcg gccgcctcct cgaaggagcg tgccgccttc acggcccggt
    15061 aggccgggag ggcccgcgcg taccagggtt cggcggcccg cgaacgcagg acctcctcgg
    15121 cgccggtgtc cgagggcagc ccgatcgagg cgaaggacgg ggtgaccagc accagccggc
    15181 gcagccgccc gggatgggcg gcggcgtaca gctgggccag ggatccgccg gccgaatggc
    15241 ccagcaggtc gaaggtctcc aggcccaggt ggccgcggag cgcctcgaca tcggccacga
    15301 gccggtcgac ccggcaggtg gcgaggtccg cgggcatcgc ggaggcgccg gagccccggg
    15361 tgtcggggag gatcagggtc cggtgcgcgc cgaggccgcc gaggtccccc aggtaggcgg
    15421 cggcgcgacc ggggccgccg ggcaggcaga cgagcggcgg ggcgccgccg tcgccggtca
    15481 cccggtaggc cagctcggta ccgtcgtacg aagtgaagaa gtgcaggtcc atgccgggta
    15541 gcctgcgggc cgccggcacc cgccgactac tgttcagcca gagctacatg gtcgggcgcc
    15601 ggacgggccc gccggacggg ggtggcggtg tccgtcgaga tcaggctgac ggcggcggag
    15661 gtggcccgcg tcagattcgc cgtgtcgccg ctggccgaga cggtgctggg cgtgcgcgcc
    15721 gcgctgacgg ccacgggcca agccgtgcac caccggtggc tggccgaggc ccgggacgta
    15781 ctccgcgatg accccgaact gcctttgctg agaaacctgc tggggcactg cctgccgtcg
    15841 ttcctgctcc cggtgccgcg tgaacggctg ccctcgctgg acgaggagct ggccgacctg
    15901 tgcgccacgg atcccgcgta cttcgcggcc gaatgcgccg ccggcgccgg cgcgcgggcc
    15961 gcggggcggc ttccggccgc cgaggtcgcc ctgccccggc tggccggcgc cctgcggcgc
    16021 tgtcacgacc gtctggtggc cccgcactgg gggcggatgc gggccgtcct cgacgccgat
    16081 gtgggccggc gcgccgtggc cctcgtcgac ggcggggtcg aggggctgtt cacgcagctg
    16141 caccgcgaca tcgcctggcg cgagggcgag ttggtcgtcg gcgggcggcg ccgggccggc
    16201 gccgcgccct gcgcggtcga agcctcgggg cacgggctgg tgctgctgcc ctccgtgttc
    16261 gcctggccgg acgtactggt cgaccggtcg ccggtgacag cggcctccat ccgctatccg
    16321 gccctcgggg tcggcctgct ctgggagccg gaccgcccca cccgcgacgg cctggccgcc
    16381 gtcctcgggg cgacccgggc ggcgctgctg gccgcgctcg ccgaaccgct gaccaccccg
    16441 gcgctggcgg cccgcctcgg ggtcaccccc agcgccgtct cccagcacct gggcgccctg
    16501 cgcggcgcgg gcctggtctc cacgcgccgg tccgggcgga cggccctgca cctgcgcacc
    16561 gcccgcgcgg tcgaccttct gaccggctga gcccgccgcg gccgccccgg accccgtccg
    16621 ggccggtgtc acccgtaccg ctcgtgtcgc cccggggaac caggggaacg atcttccctg
    16681 ccagttcgtc tggattgccc aggactgtcc gtgcgcatga ggggagcacc gtcccatggc
    16741 ccgacccgct ccgacgcccg cccggtcgcg gcgacgccgt cgtatcgcgg tcgccggggc
    16801 cgcgctgtgc gcgggcctgt tcgtgctgct ggcagtcctc gtcaccgccc ggcacggcgc
    16861 cccgtacccg ctggacagcg ccgcgcaccg ctggtccgta cggcaccggc ccgccgtcgc
    16921 cgtcgcgttc gcgcgggccg tcacctcgac cggcagcggc ccgttcccct acgcgtgcgc
    16981 cgccgcggcg ggggccatcg ccgggcgcgg cacccgcgag cggctgtggg gcgcggccgc
    17041 cgcgctgctc ttcctcggct tcgcccaggc ggtccgcttc ggtgtgctcc acctgatcgg
    17101 ccggccccgg cctcccctcg cggaatgggc caccgtggcc cacgaccact ccttcccctc
    17161 cggccacacc acggcctccg ccctcgcggc cgggctgctg gcctgggcgc tcctgcgtcg
    17221 cgccggtccc gccgccgccg cgatcccctg cgtgattttg gcgggctggg ccgtcgccgt
    17281 cgggctgacc cggatctacc tcggggtgca ctggcccacg gatgtcctcg ccggatggct
    17341 ttacgcgctc acctggttcg ccgtcggcta cgccgtcttc ccgtacgtcc tgcggatgtt
    17401 cacggacacc gactgacacc gcacccgaaa ggacgtgggc cgatgtgggc tgccggggag
    17461 gcgtacgaac cgtacgtcgg acggtggagc cggctggtcg ccgccgagtt cgtccgccgg
    17521 ctggccgccg cgcccggcgg cagctggcgc gacatcggct gcggtacggg cgcggtcgcc
    17581 cgggccgtgc tggccgcggc cgccccgcgc cgggtgatcg gcgtcgatcc cgcggagagc
    17641 tacgtacgcc acgcccgccg gcacctcgcc ggtccccggg ccgacttcgt cgtgggcgac
    17701 gcgctggccc tgccgttccc cgacgggcgg gcgacggcgg ccgtcagcgg gctcgtgctc
    17761 aacttcgtgc cggacccggc gcgggcggcc gccgagatgg tgcgcgtcgt cgggcccggc
    17821 gggacggtgg ccgtctacct ctgggactac ggcgaaggcg gaatgcgggc catccgtgcg
    17881 ttctgggacg ccgcccgcgc gctcgaccgg cgggccgagg ccctggacga ggcggtcagg
    17941 ttcccgctgg ccggccggaa gccgctgcgc gagctgctca ccggcgccgg gctggcgggg
    18001 gtggagaccg gtgagatcac cgtaccgacc cggttcaggg acttcgacga ctactggggg
    18061 ccgttcctgg gcggccaggg ccccgcgccc gcctatgtgg cctcgctgcc cgaggaccac
    18121 cgcgcggagc tgcgggaacg gctgcgcgcc accctgcccc gggcctgcga cggctcgatc
    18181 cgcctgaccg cgcgggcctg gacggcgtgg ggtgcgcggc cgccgggctg agcccggtca
    18241 cccgtcggcc gcagaggcag cgcgagggcc cagcgcgagg gcccagcgcg agagcccggt
    18301 gggaacgtcc caccgggccc tcgcggggtc attcggacgg cgtgccgaag gcgtgcaccg
    18361 ccctgctgaa cgcggtcatg caaggcgcgc agtagcgctc ggcggcgggg tcggcctccg
    18421 gtggaggggt ctggtcgggg ttgaggaggg atccacacag ggtgctgaag gtcgtgtcct
    18481 tcgctatgac gtgccacagg agctggcatc ggtcggctat ggactcggcg cgcatctcgt
    18541 acatgggcgt acctttccgc gctagcgcgg gcagaggaac ggaaccggcc tgttgtccat
    18601 gagagccccc cgtgacgaat gcggccaatg tgggtagacc aacagaagga aaaccagttg
    18661 gagcaggttt ggccgagcag ggaggagacc gtcgatggca tgggcttcgt ggacgacgac
    18721 aggggtcttt ccgggggccg gaggggtccg gaccgaggag gtcgggatca tttcgggaga
    18781 cctgaccgtg cacaccacct ggacgggcgc ccaagcccag gtggcggtgc agtacagcag
    18841 ctcgtcggac tggttcaccc tgtccggcag ccccgtggaa tgcgtgtcgg aaccggagag
    18901 ccgggacctg caccaggccg tggtggaggc ggtccgtggt ggaggcggca gcggcgttcc
    18961 accccattgg gccactttcg cggcctgacg gacacagcct gataacgcct cgcgacctcc
    19021 cggagtggag gatcgttcag ccttgtatga aagccatgag tcccggggcc acgatgcccg
    19081 ccaccctccc cgcccgtccg cggccacccg cagccacggc ggcggcgggt ggccggccgg
    19141 acacggtcac cgccacgggc acgccgatct acgacgcgct catcgcgcag tggtcccggg
    19201 agggccgtga gctccccctg ggcatagaac cgaccggccg cacccccgtg ccctccccct
    19261 cgcgtcagtt cgcggcccag ccgccgtcca gcggcaggga gatcccggtg atgtagccgg
    19321 tgtggggccc gcacagccag agcgcggccg ccgccacctc ctcgggctcg atcagccgtt
    19381 tgatcgcgga ccgggtcagc agcacgtccg ccaccacgtc cgcggcgccg atgccgtgcg
    19441 cggcggcctg gtccgcgatc tggccctcca ccaggggggt gcgcacatag ccggggctga
    19501 cgcagttgct ggtcaccccg tacggggccc cctccagggc ggtgaccttg ctcagcccct
    19561 ccagcccgtg cttggccgcg acgtaggcgg atttgtaggc gctggcccgc agcccgtgga
    19621 cgctggagat gttgaccacc cggccccacc ccgaggcgta catgtgcggc agcacccggc
    19681 gcagcagcag gaacggcgcg gtgaccatca cccgctggat cagggcgaag cgctcgacgg
    19741 ggaactgcgt gatcggcgcc acgtgctgga gccccgcgct gttgaccagg atgtccacat
    19801 gggcgggcag ctcctcgatg gccgccgggt cggcgaggtc ggtcacgtgc gcccgccccc
    19861 ggacgagacg ggccacggac gccgccgaag gcgcgtcgac gtccacgacg tgcacggcgg
    19921 cgcccgccgc cgccagggcc accgcgcagg cccggccgat tccgctgccg ccaccggtca
    19981 ccaaagcgac gcgcccccgc aggtccaccc ccgcggggcc gggcgcgggc aggggaagcg
    20041 cgggaggaag tttgctcgtc atggttcgca acagtaagga cggcccgccc gcgcgcccat
    20101 ggcgtggcgc accacactcc cggccggggc agtgtcggcg gccgccatac ggggcgggag
    20161 tccgccgtcc cccgggagcc ggggccgctc aggcatggtg cgcgggcccc gtcgtcttct
    20221 acggtgcctc cagcactcac cacctggagg caccgtatga cccctgacat agacaccgcc
    20281 gagctcgtcg ccgccgtcaa caccgtcgag cgggcccgcc acctgttggg ggaagcccgc
    20341 gacgagctcg gcggggcggg ggtgtcgcgg gaccaggagt ggacggccgc gggaagcccg
    20401 gtgcagacgc tccagggcgc cgatgacatg caccgggggt ccggtcagtt cctggacgat
    20461 ctcgccctgg ccctgggcta cgccgccgcg ggcctggccg agcaggccct gcgtcagcgc
    20521 gagcgcgccg gccaggggtt cctcgggctg agcggtgcgg accggatggc ccggccgctg
    20581 cccgcgccga cggtcgaggc cctcgaactc ctgcgcggcc tggacctgct caccccggag
    20641 ttccgcgaac ggatcacggg ggcgctggag gcggaggccg ccacctaccc ggatccggcg
    20701 ccgcagcggc ccctgcggct gggcacctcc gggctcaccc cgacggccgg ctgaccgccc
    20761 cgctcagggg gagccggggc ggcgggcccg ggtcggctgg gcgagggact gctggccgcc
    20821 cgagggcagc atccgtacct cgccctggtc gctgatctcc gcccgtacga tcccggtgga
    20881 gtcggcgtag accggatggc cgcccggccc cttctgcgcg gtgcgcgaga cgaccacgag
    20941 gtcctcgccc tcgctctcgg gctcgccgct gccgaacacc agctcgtagc ggtcctcgtg
    21001 gtcctcgctc accgatgtgc ctcccggtcc gcgccgccgg cccgcgccga cggactgtca
    21061 ccaacctgca ccatcggatg ccggggccgg acacaccacg cggtactcag gtccgaccag
    21121 gggat
//
