LOCUS       NZ_CP115936            22637 bp    DNA     linear   CON 13-JUL-2024
DEFINITION  Streptomyces goshikiensis strain CGMCC 4.1796 chromosome, complete
            genome.
ACCESSION   NZ_CP115936
VERSION     NZ_CP115936.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces goshikiensis
  ORGANISM  Streptomyces goshikiensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7239828)
  AUTHORS   Mo,P.
  TITLE     The genome sequence of Streptomyces sporoverrucosus CGMCC 4.1796T
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7239828)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) College of Life and Environment Science,
            Hunan University of Arts and Science, No. 3150 Dongting Avenue,
            Changde, Hunan 415000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 8.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 184.03x
            Sequencing Technology             :: Oxford Nanopore PromethION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_027942015.1-RS_2024_05_27
            Annotation Date                   :: 05/27/2024 07:01:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,266
            CDSs (total)                      :: 7,170
            Genes (coding)                    :: 7,009
            CDSs (with protein)               :: 7,009
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 161
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 55 of 162
            Pseudo Genes (incomplete)         :: 131 of 162
            Pseudo Genes (internal stop)      :: 14 of 162
            Pseudo Genes (multiple problems)  :: 36 of 162
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:49:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6518586
            Orig. end                         :: 6541223
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP115936.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Mo Ping.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22637
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="19"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22637
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22637
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12637](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12637)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(355..370)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.55"
                     /tool="antismash"
     misc_feature    604..617
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.35"
                     /tool="antismash"
     gene            607..1965
                     /db_xref="GeneID:91412944"
                     /locus_tag="PET44_RS28605"
                     /old_locus_tag="PET44_28605"
     CDS             607..1965
                     /codon_start=1
                     /db_xref="GeneID:91412944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743197.1"
                     /locus_tag="PET44_RS28605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28605"
                     /product="hypothetical protein"
                     /protein_id="WP_008743197.1"
                     /transl_table=11
                     /translation="MDTHEDLGTGSGHPWFGRHRLRPAAPADTIRRMLRHELRDTGWPY
                     QRVLPAAPMAIPRASYAEIFRVSVALIELLRRTALESGPTTADRLSAYDMPATEDRLWM
                     GDPFVEERYADSVVRPDLVIGPDGPRFLEFNVSGALGGVVETRSRLAVWRGLHADEDGR
                     TPFRSPDPFDVRADMFRSLGAELGLAPRVAVVGSARVIGVERRYFEMEADHYNSHGLTA
                     RFFEPEELPEAWDCAPHLRHQVGLRNFTIPDWLEVGIDTTPVQDALDNGCLLVGTQTST
                     FMHSKLTMGLLSEGRPWMTAADRGLVERYLPWTRILSERKTDREGQQVDLLPFVLGNRE
                     LLVLKAGLGESGKQVVIGREVDQAGWESAVGAAVAGGTSVVQAFVEPQTCRVSLIADGC
                     DEPYDADVAPVLGPLVFGGRPAGLFCRFFGDGSAGIVSVRGGTSSSDNVMVAI"
     gene            2025..2306
                     /db_xref="GeneID:91412945"
                     /locus_tag="PET44_RS28610"
                     /old_locus_tag="PET44_28610"
     CDS             2025..2306
                     /codon_start=1
                     /db_xref="GeneID:91412945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156263.1"
                     /locus_tag="PET44_RS28610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28610"
                     /product="DUF3253 domain-containing protein"
                     /protein_id="WP_008743196.1"
                     /transl_table=11
                     /translation="MTHGDRETERRLERAILELLEGRGPTATICPSDAARAVYAGSDDG
                     WRVLMEPARRAARRLVGAGEVEITQAGRPVDPATARGPVRIRTARRRP"
     gene            complement(2324..2986)
                     /db_xref="GeneID:91412946"
                     /locus_tag="PET44_RS28615"
                     /old_locus_tag="PET44_28615"
     CDS             complement(2324..2986)
                     /codon_start=1
                     /db_xref="GeneID:91412946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031786.1"
                     /locus_tag="PET44_RS28615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28615"
                     /product="deoxynucleoside kinase"
                     /protein_id="WP_037794821.1"
                     /transl_table=11
                     /translation="MPVICVGGMIGIGKTSVAELIAKELGSEVFFESVEDNPILPLFYT
                     ASPEEIQAKRYPFLLQLYFLQTRFASIKDAYHRADNVLDRSIYEDWYFAKVNHDLGRIS
                     SLEMQVYEGLLGEMMREIEGLPYRKAPDLMVYLKADFETVMYRIGLRGRDFEQDEALVE
                     YYRTLWSGYDDWVHKHYSASDVLVIDMNRTDVVNNPEDAARVAQEVKDALAAVAARR"
     gene            complement(3246..3797)
                     /db_xref="GeneID:91412947"
                     /locus_tag="PET44_RS28620"
                     /old_locus_tag="PET44_28620"
     CDS             complement(3246..3797)
                     /codon_start=1
                     /db_xref="GeneID:91412947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003999362.1"
                     /locus_tag="PET44_RS28620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28620"
                     /product="YciI family protein"
                     /protein_id="WP_008743194.1"
                     /transl_table=11
                     /translation="MEFFCYHRDRPGSTALRMELLERHWSYMDQYEKELIARGPTFAPG
                     GDAPSGSVHIVDLPDPAAARAFAFDEPGYQAGVYRDVLLLRWRDMLGRTMWDFPGGRTG
                     GNRYLVLGLGAGGAADLTAAPGCRNDLIAYGPLLSDDATTWLGTAALVRAPDADAARGV
                     LDVERYADIEIHPWEFGGRR"
     misc_feature    complement(3781..3797)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.34"
                     /tool="antismash"
     gene            3909..4097
                     /db_xref="GeneID:91412948"
                     /locus_tag="PET44_RS28625"
                     /old_locus_tag="PET44_28625"
     CDS             3909..4097
                     /codon_start=1
                     /db_xref="GeneID:91412948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014050098.1"
                     /locus_tag="PET44_RS28625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28625"
                     /product="DUF6381 family protein"
                     /protein_id="WP_037794818.1"
                     /transl_table=11
                     /translation="MSVEDPSGKRAQEMRDKAQELEQAAQYAADPAERQRLTQKALHIR
                     EKSEQVYGFGAGTMDPM"
     gene            complement(4117..5061)
                     /db_xref="GeneID:91412949"
                     /locus_tag="PET44_RS28630"
                     /old_locus_tag="PET44_28630"
     CDS             complement(4117..5061)
                     /codon_start=1
                     /db_xref="GeneID:91412949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743192.1"
                     /locus_tag="PET44_RS28630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28630"
                     /product="5'-nucleotidase"
                     /protein_id="WP_124290460.1"
                     /transl_table=11
                     /translation="MRYDLSGRLVVGIASSALFDLTDCDAVFREQGEDAYRAYQEAHAD
                     HALAKGVAFPFVRRLLSLNDLSDRSDPLVEVIILSRNDPDTGLRVMRSITAHHLPISRA
                     VFRQGRPSHSFMRALNMSLFLSANGADVRDAVAAGLPAGHVLHTARIDDESDPELRMAF
                     DFDGVLAGDASERVFQSLGLDEFRAHEVREAATPHDPGPLRPFLAGVNRIQRREEERRR
                     GDPAYQPRLRVSLVTARDAPTHERAIRSLKDWGLRVNDAFFLGGIEKTAVMRTLDPHIF
                     FDDQVSHLNGTAHGTPSVHVPFGVVNAQPPATT"
     gene            5424..6029
                     /db_xref="GeneID:91412950"
                     /locus_tag="PET44_RS28635"
                     /old_locus_tag="PET44_28635"
     CDS             5424..6029
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91412950"
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142169.1"
                     /locus_tag="PET44_RS28635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28635"
                     /product="response regulator transcription factor"
                     /protein_id="WP_271244891.1"
                     /transl_table=11
                     /translation="MTKVLVLHSVCLVRSALAALLRTEGDFDVTSCGWRAAGRQAASSR
                     PDVAVVDLDCPGASAALLADADAARPFPRSTPLLVLARADTPGSLRRAFLTQAQGYVDK
                     DGSPARLVRAIGRVAAGERSIDATLASAFMEADPMPLSPRELSVLARAAEGDSIAEIAR
                     ALHLASGTVRNYMAAVTRKTGARNRIDAIRISRRAGWV"
     gene            complement(6061..7803)
                     /db_xref="GeneID:91412951"
                     /locus_tag="PET44_RS28640"
                     /old_locus_tag="PET44_28640"
     CDS             complement(6061..7803)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91412951"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972311.1"
                     /locus_tag="PET44_RS28640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28640"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_271244892.1"
                     /transl_table=11
                     /translation="MSGDGSWRRVSREGRRFLRGRYRSLRRLALWSLLESAHTFLGGYA
                     VARALDDGFLAGRTGTGLGWLAVAGAGALLGALALRGVFGGLADLVEPLRDGLVRRSVR
                     QAIGRAVADPGRAGDAGAVSRLTQQTEMARDSFAGLVLVARSFVFTALGALLGLAALDP
                     VLLVLVLPALLLGTAGFLATLRPMARVQRAALDADEALSGRAGELAAGLRDVVACGGGA
                     SAGAPVERLIAEQERLTGRLARWSALRTLALGVAGRLPVVALLAGTPWLLGRGVSAGAV
                     AGALTYLVQSLLPALDALMTAVGAAGTRLLVVLDRFCAPQPDSAAATTAPAVAPGVGAG
                     PGVAVELRGVWFAYGPRAQPVIDGLDLTVGAGEHLAVVGPSGIGKSTLTALIAGLLPPG
                     GGTVRVAGAPAQRVTGPGPDLRRTLLPQQAYVFTGTVRENLTHLCPGPVSGAEVERATA
                     ALGSDGLVDRLGGLDGAVDPARLSPGERQHLALTAAYLSPAPLLLLDEATCHLDLRTEE
                     RAERALAARPGTLVVVAHRISSAARADRVLVLDGTRAVCGTHAELPARSPLYRDLVGLW
                     NARG"
     gene            complement(7800..9800)
                     /db_xref="GeneID:91412952"
                     /locus_tag="PET44_RS28645"
                     /old_locus_tag="PET44_28645"
     CDS             complement(7800..9800)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91412952"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016570340.1"
                     /locus_tag="PET44_RS28645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28645"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_271244893.1"
                     /transl_table=11
                     /translation="MTAPDPTREAEAARGADRALRAAARHSGGRLAAAAVCSVAASGAA
                     LAEPAVLGHTLDLLLRQDPGGARWTAWCAAVIAAEVLLDAVTARLTGGVDARSTAWLRR
                     LGLGRLLRAAPHHAARHSPGELSARLTAQATTAGAVPAAVVGAAVALLAPLGGLVALVL
                     VDVWTALAFLAGLPLLALLLRAFARDSGASVGRYQEVQLAMAGRLVEALAGARTIAAAG
                     TAGREQARVLRRLPELGAEGRETWRIYGTTMARTGALMPLLLYVVLGVGGIRLAEGALG
                     VGGLLAAVRYAGLAAGVGAVTGRLAAVVRGRAAARRTAALFELPELPQGVSRLPPGGPG
                     ALELRGVRVLRGGTAVLRDIDLRIPGGTTAAVVGRSGSGKTTLAAVAGRLTACDAGRVL
                     LDGVPLDELSAGELRREVGHAFERPALFGEDVAAAIAFGSGPAPPPENVRAAARAAGAD
                     AFVRRLPDGYDTALPDAPLSGGELQRLGLARAFCRAGRLLVLDDATSSLDTLTAREVER
                     ALTHDVRPGTRLVVAHRISSAARADLVVWLDAGRVRATGSHTELWRDPAYRAVFATGTD
                     PADPPNTQPAAAPVPPAAGRPDAQRNTGSDAAAGAAPARAEGTGSEPVAAASPRTGAAP
                     GEGPDAGASAGTGSAAAGGGGRRAPGRETVR"
     gene            complement(9867..10004)
                     /db_xref="GeneID:91412953"
                     /locus_tag="PET44_RS28650"
                     /old_locus_tag="PET44_28650"
     CDS             complement(9867..10004)
                     /codon_start=1
                     /db_xref="GeneID:91412953"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017946992.1"
                     /locus_tag="PET44_RS28650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28650"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_030723876.1"
                     /transl_table=11
                     /translation="MTLLDLQSMETPKEETTEAAHGGGGGSRASLLLCGDSSLSITTCN
                     "
     CDS_motif       complement(9942..10004)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTLLDLQSMETPKEETTEAAH"
                     /locus_tag="PET44_RS28650_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9867..9941)
                     /prepeptide="core"
                     /locus_tag="PET44_RS28650_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="20.90"
                     /molecular_weight="2100.3"
                     /monoisotopic_mass="2099.0"
                     /core_sequence="GGGGGSRASLLLCGDSSLSITTCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTLLDLQSMETPKEETTEAAH"
                     /leader_location="[9941:10004](-)"
                     /alternative_weights="2118.3"
                     /alternative_weights="2136.3"
                     /alternative_weights="2154.4"
                     /alternative_weights="2172.4"
                     /alternative_weights="2190.4"
     gene            complement(10001..12637)
                     /db_xref="GeneID:91412954"
                     /gene="lanKC"
                     /locus_tag="PET44_RS28655"
                     /old_locus_tag="PET44_28655"
     CDS             complement(10001..12637)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91412954"
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849361.1"
                     /locus_tag="PET44_RS28655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28655"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_271244894.1"
                     /sec_met_domain="micKC (E-value: 9.9e-240, bitscore: 796.5,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.8e-11, bitscore: 42.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.6e-06, bitscore:
                     25.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKGYAAFCDADRWFYDAPYRRAEENYPAALAPVPAGWQTHRSGD
                     WLALRPLDARLPSQGWKIHVSACLDNAESVLERVYRYCVERRIAFKFVPSRYLLHLRNA
                     KYADRAASGKFLTVYPADEEQCGRIAEELDALLAGEPGPYILSDLRWNGGPVHLRYGSF
                     TLRHCYDDRGDLVPAIEAPDGRLVPDPRGPVFQTPEWVELPAFLAPHLAERAAVTLEGL
                     PYTVERALHFSNGGGVYAGRDVRTGEPVVLKEARPFAGLAADGADAVTRLDRERRALEQ
                     LAGLDCVPAVHGTFTVGDHHFLVMRYLEGKPLNTYFARRHPLIEADPDPAELAEYTRWA
                     LEIHRRVTEAVEAVHARGIVFNDLHLFNIMVAEDEETGEPSVSLLDFEAAAHVDEGLRQ
                     TVANPAFVAPADRRGVAVDRYALACLRLALFLPLTSLLVLDRGKAAHLADIAAEQFPVP
                     REFLDEAVREILAGAEGAPPAVVPRRPYLPVEPGDWEAARASMTAAIRASATFDRDDRL
                     FPGDTAQFANAGGGTGFGYGAAGVLYALAETGADPWPEAEEWLLARTKEPASGMPLGFY
                     DGLAGIAWTLERLGHRDRALALAEQLLGQPWQSAGPDLHGGLAGIGLALDSLGTATGES
                     ALHAAALRCADLLAESEAATGSKRAGLLHGNSGPALLHLRLYERTGDRESLLRAGRALH
                     RDLDRCVTSVFGTLQVDEGWRTMPYLGAGSVGIGMVLDDWPAHTPDERFERARPEIVRA
                     AQATFYAQPSLFRGAAGMILHLARTTTPGPGSGPEDIARQVEALARHAVPYQGFLAFPG
                     EQMMRLSMDLSTGTAGALLALGSAAPGGRAQLPFLPPPRSAAAAPEPVPLVGAVSHRNT
                     TVKRNQT"
     misc_feature    complement(12029..12031)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12902..14263
                     /db_xref="GeneID:91412955"
                     /locus_tag="PET44_RS28660"
                     /old_locus_tag="PET44_28660"
     CDS             12902..14263
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91412955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018560948.1"
                     /locus_tag="PET44_RS28660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28660"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_037798702.1"
                     /transl_table=11
                     /translation="MGRRWAARLSLAAGVAALLVLVVFGGLVSLVLMGVGWAGLALSAA
                     GVWWMLTHTGRIRVLAVLLLVAVPLAVLALYAAAGLLWVVLVSLGLWALAVFAGRAALV
                     EDAPPAMPEHPARRPERPFLIMNPRSGGGKVTKFRLAERARALGAEVVVLDPDRPQDVV
                     QLAREAVRRGADLLGVAGGDGTQALVAGVAVAHDLPFVVISAGTRNHFALDLGLDRKNP
                     ARCLEALTDGVELRVDLGYLRAGGPEEPEEPAEPGTEAVFVNSASFGVYAEVVQSPAYR
                     DDKVRTILEMLPDLLAQESGARLSVRGDGPVLDAPQAVLVSNNPYQRGDSAGLGRRERL
                     DTGELGVLGVHVGSAAEAAELLLRGGQQGRGLTETTAREVVVDADAPVIPVGVDGEALT
                     LPTPVRCRLAPGALRVRVPRHRPGVRLGAPPMDWRRVRRLALTMGRAAAGRGPA"
     gene            complement(14289..15671)
                     /db_xref="GeneID:91412956"
                     /locus_tag="PET44_RS28665"
                     /old_locus_tag="PET44_28665"
     CDS             complement(14289..15671)
                     /codon_start=1
                     /db_xref="GeneID:91412956"
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005320966.1"
                     /locus_tag="PET44_RS28665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28665"
                     /product="MFS transporter"
                     /protein_id="WP_073798485.1"
                     /transl_table=11
                     /translation="MSDTRTPRRPSGAQRRVLAPLALAQFICSFAGSNMNVMINDISED
                     LDTTVQGVQTAITIFLLVMAALMIPGGKLTDRYGRKRCLLVGLVVYGIGALLSAAAPGL
                     GVLILGNSILEGIGTALLIPPVYILTTLIFTDLASRARAFGVIMALGGIGAAAGPLIGG
                     LITSALSWRAAFVFQALVIAVIILLSRRLEDPLPPDPTRSFDTTGAVLSAAGLILVVMG
                     ILAADDSLWLTLALLALGALVLLGFFRSVRAKERAGKEPLLSTALFRDRTSNLGLVTQN
                     VQWLLLMGSSFTVAAYLQVVRGYDAVQTGVIFTAATLGLLVSSLAAERLAQRWPQRTLI
                     VTGFLATLAGIVVLIALAGSSPNPWALTPGLLLIGLGLGVMLTPSVNVVQSSFPEEQQG
                     EISGLSRSVSNLGSSLGTAVAGTILVAGLSTGAYAAAMIALAVIGLVGLAAALLLPRTP
                     AR"
     gene            complement(15819..17195)
                     /db_xref="GeneID:91412957"
                     /locus_tag="PET44_RS28670"
                     /old_locus_tag="PET44_28670"
     CDS             complement(15819..17195)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91412957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433022.1"
                     /locus_tag="PET44_RS28670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28670"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_124290463.1"
                     /transl_table=11
                     /translation="MPEDTAGSGFARLLRELKDRSGLSYGTLAKRLHMSTSTLHRYCTG
                     DVVPTEYAPVERFARLCKASPEELLELHRNWVLADTNRPRRGAGEAEGPARAAAAPATP
                     PSSPSSPSSPSPQESGPGATQEPAPADTAPSAAAAERRRRPRAAALAGIAAGVVAGTIG
                     AVALTAHLTSRDADVRDRPAAAASPAPGAGKRADGRTASPAPSAPSPSASEPAGAGAGT
                     AAPPAPSGSGARSGPASGSGSAPGAPAGDGAVSGTPVKVTAQPYTWESPCGQHYLIEKP
                     PSEVGPPPLERDAPAWVAASRAVSAGEQYVTLTLQGSGKETVVLDGLTVRTVGKHAPLA
                     WNDYAMGYPGVGCGAGVPTRSFTVALDAARPAVVPAPDQPDFPFKVSESEPEVFYVKAD
                     ASKYDVSWYLELSWSSGSRHGTLTIDHNGKPFRTSGLGGRPGYEFPLGGDGWVKAGTTS
                     "
     gene            17409..18161
                     /db_xref="GeneID:91412958"
                     /locus_tag="PET44_RS28675"
                     /old_locus_tag="PET44_28675"
     CDS             17409..18161
                     /codon_start=1
                     /db_xref="GeneID:91412958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070308.1"
                     /locus_tag="PET44_RS28675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28675"
                     /product="DUF4232 domain-containing protein"
                     /protein_id="WP_078899759.1"
                     /transl_table=11
                     /translation="MSAFRSTPATSTSRATLPRAARRLGGAAALALAALALTACQDGKG
                     LQDEGAATFSDSAVATPSATATPGAGSGSASGSATKTGSATKSGGAKATGGDAKGSSAP
                     SAEGDRVTCNGSNTAVTVQTVSRPLNHMLITVKNTGKKNCDLTYYPVLRFDEMQWAPAA
                     RKDTQPQAVVTLAPGRSGYAGALLSAADGSGEGGVTGHRLTIAFQGRTSHSDGGASAVP
                     SLPAAGVYYDSSLTVTYWQQSASDALGS"
     gene            complement(18156..19568)
                     /db_xref="GeneID:91412959"
                     /locus_tag="PET44_RS28680"
                     /old_locus_tag="PET44_28680"
     CDS             complement(18156..19568)
                     /codon_start=1
                     /db_xref="GeneID:91412959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017949629.1"
                     /locus_tag="PET44_RS28680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28680"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_124290465.1"
                     /transl_table=11
                     /translation="MTYISGDRESGPTRRALLVAGAGAALAAGCAPGGTPGAPAPTPSG
                     SAPSGLAAATGPTPGAMTLFKDPGYNFNGLLALGASGAGAAEVGEVLTAVNAINGAGLS
                     AQTYVDTFRKLGDQLLGPPPGSPADAQTKRFRALRAAQYYGQALFFVLGSKDPGSEEQL
                     YKAGRDAWDAFCDLCEPAPVKAAVPYGTTPLPVWFFRPDTSNTPRPTVILTNGSDGQNV
                     DMWTYGVPAALERGWNALVYDGPGQGQLLFVDRVVFTPTWEKVVSPLVDWLSARPDVDQ
                     DRIALTGLSMAGDLAPRAAAFESRIAALVAMPGCVEPWLGFPPEIREILTPSKEETNDI
                     WNTKVVPELPPEAAAVLKKRFEPFSIPAMLQARQGKLFTDFYTPATRIQALSIASVVSR
                     IKAPTLVLDYEDEQFYPGQPRQLYDALTSPKDYLKLTAAQGAQLHCSPMAPQLHCEVVF
                     DWLQETLPGGGS"
     gene            complement(19663..20379)
                     /db_xref="GeneID:91412960"
                     /locus_tag="PET44_RS28685"
                     /old_locus_tag="PET44_28685"
     CDS             complement(19663..20379)
                     /codon_start=1
                     /db_xref="GeneID:91412960"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PET44_RS28685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PET44_28685"
                     /product="sel1 repeat family protein"
                     /protein_id="WP_037798710.1"
                     /transl_table=11
                     /translation="MRWNGVDFTVDGREPTTAEEFHRIGLHCWQDPRHREAAAFFLEPA
                     ARAGHAEAAELLGHVLFSRGEYAAAAPWLRGSAGTSRRAAHYLGRLSYDGCPPAGITAS
                     YADAAHWYREAARLGEPEAMLALGEMYLERLLPLTGAPVAHALELFAAAAELGHPYAQF
                     RSAELYRTDFAAPDPAARCYELCLANPATATHPLGSLMTQQSRWHLSHIRAAGDAERSG
                     RERDRLHPRPPDEPRY"
     gene            20676..21146
                     /db_xref="GeneID:91412961"
                     /locus_tag="PET44_RS28690"
                     /old_locus_tag="PET44_28690"
     CDS             20676..21146
                     /codon_start=1
                     /db_xref="GeneID:91412961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063518.1"
                     /locus_tag="PET44_RS28690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28690"
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="WP_037798713.1"
                     /transl_table=11
                     /translation="MSVVKNALPEADLKVVGEALQGALVDLVDLGLVAKQVHWNVVGPR
                     FRSVHLQLDEVVTSARTHSDVVAERASALGITPDGRAATVASSSAISGVPEGWVKDVDA
                     VRILVDGLSAVITRMRERIQATADPDPVTQDILITVTGDLEKHHWMFAAESA"
     gene            complement(21175..21963)
                     /db_xref="GeneID:91412962"
                     /locus_tag="PET44_RS28695"
                     /old_locus_tag="PET44_28695"
     CDS             complement(21175..21963)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (8-114). E-value: 6.7e-09. Score:
                     27.8. Matches aSDomain:
                     nrpspksdomains_PET44_RS28695_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GeneID:91412962"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009062680.1"
                     /locus_tag="PET44_RS28695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28695"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_037798716.1"
                     /transl_table=11
                     /translation="MLIDLSGRTALVTGSTQGIGAAIAAGLAAAGARVAVNGRSRASVE
                     EALARLRASGGEFVAAPGDITTDEGARSVFEAVPRTDILVNSLGVFGPAKALEIEDDEW
                     RRYFDTNVLTAVRMIRRYLPGMMERSWGRVQNIASDSAVAVPAEMIHYGMSKTALLAVS
                     RGFAKEAAGTGVTVNSVIAGPTHTGGVEDFVYELVDRNLPWDEAQRAFMRTHRPQSLLQ
                     RLIEPEEIAHMVVYLSSPFASATTGGALRVDGGYVDSILP"
     aSDomain        complement(21622..21939)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PET44_RS28695_PKS_KR.1"
                     /evalue="6.70E-09"
                     /label="PET44_RS28695_PKS_KR.1"
                     /locus_tag="PET44_RS28695"
                     /protein_end="114"
                     /protein_start="8"
                     /score="27.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TALVTGSTQGIGAAIAAGLAAAGARVAVNGRSRASVEEALARLRA
                     SGGEFVAAPGDITTDEGARSVFEAVPRTDILVNSLGVFGPAKALEIEDDEWRRYFDTNV
                     LT"
     CDS_motif       complement(21844..21933)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_PET44_RS28695_0001"
                     /evalue="6.30E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="PET44_RS28695"
                     /protein_end="40"
                     /protein_start="10"
                     /score="15.6"
                     /tool="antismash"
                     /translation="LVTGSTQGIGAAIAAGLAAAGARVAVNGRS"
     gene            complement(22138..22539)
                     /db_xref="GeneID:91412963"
                     /locus_tag="PET44_RS28700"
                     /old_locus_tag="PET44_28700"
     CDS             complement(22138..22539)
                     /codon_start=1
                     /db_xref="GeneID:91412963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011027199.1"
                     /locus_tag="PET44_RS28700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PET44_28700"
                     /product="hypothetical protein"
                     /protein_id="WP_235441287.1"
                     /transl_table=11
                     /translation="MSLPYRTVALPPVDGTVCDPAPPPPQPWTGVVRGVPAGEGEGPGA
                     RVGGREAAAGVETCGLEAEGDAEGLAEAEGEPEPETEAEGEAEALGERNTVGADRATGG
                     FGRVEPATKSTVAMTAVTLAAVQDTHMSR"
ORIGIN
        1 cctacggcga gcgcggcatc ggctacgtac gctcccactc cccggtgctg gacgagcgga
       61 ccatcaccgt ggcgacgctg agcaagggct tcggggccgg cggcacggcg atcctgctcg
      121 acggctaccc cgagcagacc cggcggctca tcgagcggtt cgccggaccg ctgggctact
      181 cgcagaagat gaacgccgcc gcggtcggtg cggcgctcgc ctcggccgag atccaccgca
      241 ccgaggaact cagcctgctt caggggcggc tgcggtccag catcgcgctg ttcgactcgc
      301 tggtcgcgac cgagcagtcc gacagcacct acccgatccg ggtggtgccg atgaccgacg
      361 agacggtcat cgacgccgcc aagcaggtct tcgcggccgg gttctacacc tcgccggtgt
      421 tcttcccgat cgtcgcccgg ggcaccgcgg gactgcgcgt gatgctccgg gccggccaga
      481 gcgaggagca gatcaggcgg ctctgcgcgg cgctggtccg ggccggagcc cgcccggcgg
      541 ccgcggcacc cgcgccggga acgggcggcg aacacctcgc cgcgacgaca ggggaaggag
      601 cgccggatgg acacgcatga ggacctcggc acgggaagcg ggcacccgtg gttcggccgt
      661 caccggctgc ggcccgcagc gcccgcggac accatccggc ggatgctgcg gcacgagctc
      721 cgggacaccg gctggccgta ccagcgggtc ctgcccgcgg cgccgatggc gatcccgcgg
      781 gcgtcctacg ccgagatctt ccgggtgagc gtcgcgctga tcgagctgct gcgccgtacc
      841 gccctggaga gcggacccac caccgccgac cggctgagcg cctacgacat gcccgccacc
      901 gaggaccggc tgtggatggg cgaccccttc gtcgaggagc ggtacgccga ctccgtggtc
      961 cgtccggacc tggtcatcgg cccggacggg ccgcggttcc tggagttcaa cgtcagcggc
     1021 gcgctcggtg gcgtggtgga gacgcggagc cggctggcgg tgtggcgcgg gctccacgcc
     1081 gacgaggacg gccggacgcc gttccgctcc ccggacccgt tcgacgtccg cgcggacatg
     1141 ttccggtcgc tcggcgcgga gctcgggctg gcgccgcggg tggccgtcgt cggcagcgcc
     1201 cgggtgatcg gcgtggagcg gcggtacttc gaaatggagg ccgaccacta caacagccac
     1261 ggcctgaccg cccgcttctt cgagccggag gagctgcccg aggcgtggga ctgcgccccg
     1321 cacctgcgcc atcaggtcgg gctgcgcaac ttcaccatcc cggactggct ggaggtgggc
     1381 atcgacacca cgccggtcca ggacgccctg gacaacggat gcctgctggt gggcacccag
     1441 acctcgacct tcatgcacag caagttgacc atggggctgc tgtcggaggg gcgcccctgg
     1501 atgaccgcgg ccgaccgcgg gctcgtcgag cggtacctgc cgtggacgcg gatcctctcg
     1561 gagcgcaaga ccgaccggga ggggcagcag gtcgacctgc tcccgttcgt gctgggcaac
     1621 cgggagctgc tggtgctcaa ggcgggcctg ggggagagcg ggaagcaggt cgtcatcggc
     1681 cgcgaggtcg accaggccgg gtgggagtcc gccgtcggcg cggccgtcgc cggcggtacc
     1741 agcgtggtgc aggccttcgt ggagccgcag acctgccggg tctcgctgat cgccgacggc
     1801 tgcgacgagc cgtacgacgc ggatgtcgcc ccggtcctcg ggcccctggt gttcggcggc
     1861 cgcccggccg gactgttctg ccggttcttc ggcgacggca gcgccgggat cgtcagcgtc
     1921 cggggaggga cgagcagctc cgacaacgtg atggtggcca tctgacggcg ccgcccccgc
     1981 ccggacgccc cggtttcccg cgccgccggt gcgacactga tggtgtgacg cacggcgacc
     2041 gggagactga gcgacgtttg gagcgggcca tcctggagct gctggagggt cgcggcccca
     2101 ccgcgacgat ctgcccgtca gacgccgcgc gggccgtgta cgcgggcagt gacgacggct
     2161 ggcgcgtgct catggaaccg gcccgccggg cggcccggag gctggtcggc gcgggcgagg
     2221 tggagatcac ccaggccggc cgccccgtcg accccgctac ggcccgcggg ccggtccgta
     2281 tccggaccgc ccgccgacgg ccgtaatcag ccggccggcg ggctcagcgg cgggccgcga
     2341 ccgccgccag ggcgtccttg acctcctgcg ccacgcgggc cgcgtcctcg gggttgttca
     2401 ccacgtcggt gcggttcatg tcgatgacga ggacgtcact ggccgagtag tgcttgtgca
     2461 cccagtcgtc gtagccggac cacagcgtcc ggtagtactc gacgagggcc tcgtcctgct
     2521 cgaaatcgcg gccgcgcagg ccgatgcggt acatgaccgt ctcgaagtcc gccttgaggt
     2581 agaccatgag gtcgggtgcc ttgcggtacg gcaggccctc gatctcgcgc atcatctcgc
     2641 ccagcagccc ctcgtacacc tgcatctcaa gggagctgat ccggccaagg tcgtggttga
     2701 ccttggcgaa gtaccagtct tcgtagatgg accggtcgag gacgttgtcg gcccggtggt
     2761 acgcgtcctt gatcgaggcg aaccgcgtct ggaggaagta gagctggagc aggaaggggt
     2821 agcgcttggc ctggatctcc tcggggctcg ccgtgtagaa gagcggaagg atcgggttgt
     2881 cttccacgct ctcgaagaag acctcgctgc ccagctcctt ggcgatcagt tcggcgacgc
     2941 tcgtcttgcc gattccgatc atgcctccga cgcagatcac tggcatacct cacttctccc
     3001 tgggggtctt ctgttcctgg gccggcgcgc ggggcgtccc acgtcaatga gacgcacgcc
     3061 ggcggtcacg cgattccccg ggatcttcgt gatcagtgcc gtgtggtcct cgtccggacc
     3121 acggctctga ccacggccgc tctcctcgac gcgcacggcg acgagccgca ggtccgcggc
     3181 cgtcctgaat cttaagtgat gatccgcccc gtgcgggcca gagcgggggc ggccaaggcc
     3241 gggcgtcagc gccgcccgcc gaactcccac gggtggatct cgatgtccgc gtagcgctcc
     3301 acgtccagga cgccgcgcgc cgcgtcggcg tccggggccc ggaccagcgc cgccgtaccc
     3361 agccaggtgg tggcgtcgtc ggacagcagc gggccgtacg cgatcaggtc gttccggcag
     3421 ccgggcgccg cggtgaggtc ggcggccccg cccgcgccga ggccgaggac caggtaccgg
     3481 ttgcctccgg tccggccacc ggggaagtcc cacatggtgc gccccagcat gtcgcgccag
     3541 cgcagcagca gcacgtcccg gtacacgccg gcctggtagc cgggctcgtc gaaggcgaac
     3601 gcgcgcgcgg cggccggatc ggggaggtcg acgatgtgca cgctgccgct gggggcgtcg
     3661 ccgccggggg cgaaggtcgg gccccgggcg atcagctcct tctcgtactg gtccatgtag
     3721 gaccagtggc gttccagcag ttccatgcgc agggccgtgg agccggggcg atcgcggtgg
     3781 tagcagaaga attccatgct gctggactct ctccgagaac cggctgaaga tcaacggtcc
     3841 ggggccggtg aatgccgccc ggatgccggg gtagggggat ccgcaccagc ccgatcgagg
     3901 aggtcgaagt gagcgtcgag gacccgtccg gcaaacgagc tcaggagatg cgcgacaagg
     3961 cgcaggagct ggagcaggcc gcccagtacg ccgccgatcc cgcggagcgg cagcggctca
     4021 cgcagaaggc gctgcacatc cgcgagaaga gcgagcaggt gtacggcttc ggcgccggga
     4081 ccatggaccc catgtagccc ggacacggcc ggcggttcag gtggtcgcgg gaggctgcgc
     4141 gttgaccact ccgaaaggga cgtgcacgct cggggtgccg tgcgccgtgc cgttcagatg
     4201 ggagacctgg tcgtcgaaga agatgtgcgg gtcgagggtg cgcatcaccg ccgtcttttc
     4261 gatgccgccg aggaagaagg cgtcgttgac ccgtagcccc cagtccttga ggctccgtat
     4321 ggcgcgctca tgggtggggg cgtcccgagc ggtgaccagg gacacccgaa ggcgcggctg
     4381 atacgcggga tcgccgcgcc ggcgctcctc ctcccggcgc tggatgcggt tgacgcccgc
     4441 gaggaagggg cgcagcggtc ccggatcgtg gggggtggcg gcctcgcgga cctcgtgcgc
     4501 gcggaattcg tcgagtccga ggctctggaa gacccgctcc gaggcgtcgc ccgccagcac
     4561 tccgtcgaag tcgaaggcca tgcggagttc ggggtcgctc tcgtcgtcga tccgcgccgt
     4621 gtggagcacg tggccggcgg gcagtcccgc cgcgaccgcg tcccggacgt cggctccgtt
     4681 ggccgacagg aacagcgaca tgttcagcgc gcgcatgaag gagtgcgagg ggcggccctg
     4741 ccggaacacc gcccggctga tcggcaggtg gtgcgccgtg atcgaccgca tgacccgcag
     4801 cccggtgtcg gggtcgttgc gcgagaggat gatgacctcg accaggggat cggaccggtc
     4861 cgagaggtcg ttcagcgaca gcaggcgtct gacgaagggg aaggccaccc ccttggccag
     4921 ggcgtggtcc gcgtgcgcct cctggtaggc ccggtaggcg tcctctcctt gctcccggaa
     4981 caccgcgtcg cagtcggtca ggtcgaacag ggcgctggag gcgatcccca ccaccagacg
     5041 accggacagg tcgtaccgca tgaagccccc cgttgaacgc gatcggaacg atggggggct
     5101 tatcgccctc cggcatatgc ggaaaacgtc cgccggggtg attctgaggt cccggacggg
     5161 ccctcggcgg cccccgggcg gtgtgcggag ccgcacccat gcgggcggaa tcagcccatc
     5221 cggttgttgg gtccgcgccc cggcgggcgg gggtttcgcg atgcctgccg aggtcgggcg
     5281 gccgtgggcc gtgcgggagc ggcgggaggc gggcgtcagg cttcggccac ccgctcccgc
     5341 gcgccgcatg ccgtgacgtt cccgcacggc actggctggg cagccggttg gtgctgattg
     5401 atcgtcacgt gaggggaacc gcgatgacca aggttctggt gctgcacagc gtgtgtctgg
     5461 tgaggtccgc cctcgccgcg ctgctgagaa ccgagggtga cttcgatgtc acctcctgcg
     5521 gctggcgcgc cgccgggcgc caggcggcgt cctcacggcc cgacgtggcc gtggtggacc
     5581 tcgactgtcc gggggcgtcg gcggccctgc tcgcggacgc cgacgccgct cgtccgttcc
     5641 cgcgctccac gccgctgctc gtcctcgccc gcgccgacac ccccggctcg ctgcggcgcg
     5701 ccttcctgac ccaggcgcag ggttacgtcg acaaggacgg ctcgcccgcc cggctggtcc
     5761 gggccatcgg cagggtcgcg gccggggaac gctccatcga cgccacgctc gcctcggcct
     5821 tcatggaggc cgaccccatg ccgctcagcc cgcgcgagct gagcgtgctg gcccgggccg
     5881 ccgagggcga ctcgatcgcg gagatagccc gcgccctgca cctcgccagc ggaaccgtac
     5941 ggaactacat ggccgccgtg acgcggaaga ccggcgcccg aaaccggatc gatgccatcc
     6001 ggatttcccg gcgggccggc tgggtctgag accccggcgc cggttccccc caagcccgct
     6061 tcacccccgc gcgttccaca gacccaccag atcccggtac agcggcgacc tggcggggag
     6121 ctccgcatgc gtgccgcaca ccgcccgggt cccgtcgagt acgaggaccc ggtcggccct
     6181 ggcggcggag gagatgcggt gggcgaccac caccagggtc ccggggcgcg cggcgagcgc
     6241 ccgctcggcg cgttcctccg tccggaggtc gaggtggcag gtggcctcgt ccagcaggag
     6301 cagcggggcg ggggagaggt aggcggcggt gagggcgagg tgctggcgct cgcccggcga
     6361 gagccgggcc gggtcgacgg ccccgtccag cccgccgagc cggtccacga gcccgtccga
     6421 gccgagggcg gccgtggccc gctccacctc ggccccggat accgggccgg ggcacaggtg
     6481 ggtcaggttc tcgcggaccg tccccgtgaa cacgtacgcc tgctgaggca acagggtccg
     6541 ccgaagatcg ggcccgggcc cggtgacgcg ctgcgcgggg gcacccgcca cccgtacggt
     6601 tcccccgccg ggcggcagca ggccggcgat cagagcggtg agcgtggact tgccgatgcc
     6661 gctcggcccc accacggcca ggtgctcgcc cgccccgacc gtcaggtcga gcccgtcgat
     6721 caccggctgc gcgcgggggc cgtaggcgaa ccacaccccc cgcagctcaa cggcgacacc
     6781 cggcccggcc cccaccccgg gggccaccgc cggggccgtg gtcgcggcgg cggagtccgg
     6841 ttggggcgcg cagaagcggt ccagtaccac caggagccgg gtgcccgccg cgcccaccgc
     6901 cgtcatcagg gcgtccaggg cgggcagcag cgactgcacg aggtaggtga gggccccggc
     6961 caccgccccc gcgctcaccc cgcggccgag cagccacggc gtcccggcca gcagcgcgac
     7021 gaccggcaac cggccggcga cgcccagggc cagcgtgcgc agggcgctcc agcgcgcgag
     7081 gcgcccggtc agccgctcct gctcggcgat cagccgctcc accggggctc cggcgctcgc
     7141 cccgccgccg caggcgacga cgtcgcgcag ccccgccgcc agttcgccgg cgcgcccgga
     7201 cagcgcctcg tcggcgtcga gcgccgcccg ctgcacgcgc gccatcgggc gcaacgtggc
     7261 caggaacccg gccgtaccca ggagcagcgc gggcagtacg aggaccagca ggacgggatc
     7321 cagcgcggcc agccccagca gcgcccccag ggcggtgaag acgaacgacc gggcgaccag
     7381 gaccagtccg gcgaaggagt cgcgggccat ctcggtctgc tgcgtgagcc gggagacggc
     7441 gcccgcgtca ccggcccgcc cggggtcggc gacggcccgc ccgatcgcct ggcgtacgga
     7501 acgccgcacc aggccgtccc gcaggggctc gaccaggtcg gcgagcccgc cgaacactcc
     7561 gcgcagggcg agggcgccga gcagggcccc cgcgccggcc acggccagcc agccgagtcc
     7621 ggtgccggtg cgcccggcga ggaagccgtc gtcgagggcg cgggcgaccg cgtagccgcc
     7681 gaggaaggtg tgcgcggact ccagcaggga ccagagcgcg agccgccgca gcgaccggta
     7741 ccgcccgcgc aggaagcggc ggccctcgcg cgacaccctg cgccaggagc cgtccccgct
     7801 catcggaccg tctcccggcc gggcgcccgc cgcccgccgc cgcccgccgc ggccgatccc
     7861 gttccggcac tcgctcccgc gtccggccct tcgcccggcg ccgcacccgt tcgcgggctc
     7921 gctgccgcca ccggctccga gcccgttcct tcggcccgtg ccggggccgc gcctgctgcc
     7981 gcgtcggagc cggtgttccg ctgcgcgtcc ggccttccgg cggcaggcgg taccggtgcc
     8041 gccgcaggct gcgtgttcgg ggggtcggcc gggtccgtgc cggtggcgaa caccgcgcgg
     8101 taggccgggt ctcgccagag ctcggtgtgg gagccggtcg cgcggacgcg tcccgcgtcg
     8161 agccagacga cgaggtccgc gcgggcggcc gaggagatgc ggtgggcgac gacgaggcgg
     8221 gtgcccgggc ggacgtcgtg ggtcagggcg cgctccacct cccgggcggt gagggtgtcc
     8281 aggctcgacg tcgcgtcgtc caggacgagc agccgcccgg cgcggcagaa cgcccgggcc
     8341 aggcccagac gttgcagctc cccgccggac agtggcgcgt ccggcagcgc cgtgtcgtag
     8401 ccgtcgggca ggcggcgtac gaaggcgtcc gccccggccg cccgcgccgc ggcgcgtacg
     8461 ttctccgggg gcggcgccgg cccgctgccg aacgcgatgg cggccgcgac gtcctccccg
     8521 aacagggcgg gccgctcgaa ggcgtggccg acctcccgtc gcagctcccc ggcggacagt
     8581 tcgtccagcg gtacgccgtc cagcaggacc cgccccgcgt cgcaggcggt gagccgcccc
     8641 gccaccgcgg ccagcgtcgt cttgccggag cccgagcggc cgacgacggc cgcggtcgtc
     8701 ccgccgggga tccgcaggtc gatgtcgcgc agcaccgcgg tgcccccgcg gaggacccgc
     8761 accccgcgca gctccagcgc gcccggcccg cccggcggca accggctaac cccctggggg
     8821 agttccggca gttcgaagag ggccgccgtg cggcgcgcgg cggcgcggcc gcgcaccacc
     8881 gccgccagcc gccccgtcac ggcgccgacc ccggccgcga gtcccgcgta gcggaccgcg
     8941 gcgaggagcc cgccgacgcc gagggccccc tcggcgaggc ggatcccgcc cacgccgagg
     9001 acgacgtaca gcagcagcgg catcagggcg cccgtgcgcg ccatggtcgt gccgtagatc
     9061 cgccaggtct cccgcccctc ggcgccgagt tccggcaacc ggcgcagcac gcgtgcctgt
     9121 tcgcgcccgg cggtgccggc ggcggcgatg gtacgggcgc ccgcgagggc ctccacgagg
     9181 cggccggcca tcgcgagctg tacttcctgg taacggccca cactcgcccc cgagtcgcgg
     9241 gcgaacgccc tcaacagcag cgccagcaag gggagtccgg cgaggaatgc cagcgcggtc
     9301 catacgtcga ccaggaccag cgccacgagt ccgccgagcg gcgccagcag ggccacggcc
     9361 gcgcccacca cggccgccgg tacggcgccg gcggtggtgg cctgggcggt cagccgggcg
     9421 gagagctcac cgggggagtg gcgggcggcg tggtgcggcg cggcccgcag cagccggccc
     9481 agtcccagcc gccgcagcca ggccgtggag cgggcgtcga cgccgccggt gaggcgggcc
     9541 gtcaccgcgt cgagcagtac ctcggcggcg atcaccgccg cgcaccacgc tgtccaccgg
     9601 gcgccgccgg gatcctgtcg cagcagcagg tcgagggtgt ggccgaggac cgccggttcg
     9661 gccagggccg cgccggaggc ggccaccgaa cagacggcgg cggcggcgag acggccgccg
     9721 ctgtgtcgtg cggccgcccg cagcgcccgg tcggcgccgc gggcggcctc cgcctcacgg
     9781 gtgggatcgg gtgcggtcat gggcgacggc tccaggggtg tggtgcgggc ccgggcggag
     9841 aaccgcccgg gcccgatagg acctgactag ttacaggtcg tgatgctcag gctgctgtcg
     9901 ccgcagagga gcaggctggc gcggctgccg ccaccgccac cgtgcgcggc ctcggtggtc
     9961 tcttccttcg gggtttccat cgactgcagg tcgagaagcg tcatgtctga ttcctcttca
    10021 ctgtggtgtt ccgatgggac acggccccca cgagggggac cggctctggg gccgccgcgg
    10081 ccgaccgcgg cggcgggagg aacggcagct gtgcgcgccc gccgggcgcg gcgctgccga
    10141 gggcgaggag cgcgccggcc gtgcccgtgg acaagtccat ggacaggcgc atcatctgct
    10201 cgccgggaaa ggccaggaag ccttggtacg ggaccgcgtg ccgggccagg gcctccacct
    10261 gccgggcgat gtcctccggg ccggagcccg ggcccggggt ggtggtgcgc gccaggtgga
    10321 ggatcattcc ggcggcgccg cggaacaggc tcggctgcgc gtagaacgtg gcctgcgcgg
    10381 cgcggacgat ctccggccgg gcccgttcga agcgctcgtc cggggtgtgg gccggccagt
    10441 cgtccagcac catgccgatc cccacgctgc cggccccgag gtagggcatc gtgcgccacc
    10501 cctcgtcgac ctggagggtg ccgaagacgc tggtcacgca gcggtcgaga tcgcggtgca
    10561 gggcccggcc ggcccggagc agtgactccc ggtcgccggt gcgttcgtag agccgcaggt
    10621 ggagcagcgc gggtccgctg ttgccgtgga gcagaccggc ccgtttcgag ccggtggcgg
    10681 cctcggactc cgcgagcaga tcggcgcagc gcagggccgc ggcgtgcagt gcgctctcgc
    10741 cggtggccgt gcccagggag tccagggcca gcccgatgcc cgccagtccg ccgtgcaggt
    10801 cggggccggc cgactgccag ggctggccca gcagttgttc ggcgagggcg agcgcgcggt
    10861 cgcggtggcc gagccgctcc agggtccacg cgataccggc gaggccgtcg tagaagccca
    10921 gcggcatgcc ggaggccggt tccttcgtcc gggccagcag ccattcctcg gcttcgggcc
    10981 acgggtcggc gccggtctcg gcgagcgcgt acagcacacc ggcggctccg tagccgaaac
    11041 cggtgccgcc gccggcgttc gcgaactggg cggtgtcccc ggggaagagg cggtcgtcgc
    11101 ggtcgaaggt ggcgctggcc ctgatcgccg ccgtcatcga ggcgcgggca gcctcccagt
    11161 cgcccggctc gaccggcaga taggggcggc ggggcaccac cgcgggtggg gcgccctccg
    11221 ccccggcgag tatctcccgt accgcctcgt cgaggaactc gcggggtacg gggaactgct
    11281 cggcggcgat gtcggccagg tgcgcggcct tgcctcggtc caataccagc aggctggtca
    11341 gcggcaggaa cagggccagg cgcaggcagg ccagggcgta ccggtcgacg gcgacgccgc
    11401 gccggtccgc cggggcgacg aacgccgggt tggcgacggt ctggcgcagc ccctcgtcga
    11461 cgtgcgcggc ggcctcgaag tcgaggagcg acaccgacgg ttcgccggtc tcctcgtcct
    11521 ccgcgaccat gatgttgaac aggtgcaggt cgttgaagac gatgccccgg gcgtgcaccg
    11581 cctccacggc ctccgtcacc cgccggtgga tctccagcgc ccaccgcgtg tactccgcga
    11641 gctccgcggg gtcggggtcc gcctcgatca gcgggtgccg gcgggcgaag taggtgttga
    11701 ggggtttgcc ctccaagtac cgcatcacca ggaagtggtg gtccccgacg gtgaaggtgc
    11761 cgtgcaccgc gggcacgcag tccagcccgg ccagctgctc cagggcccgg cgttcgcggt
    11821 ccagccgggt cacggcgtcc gccccgtcgg ccgcgagccc cgcgaagggg cgcgcttcct
    11881 tgaggacgac cggctcgccg gtgcggacgt cacggccggc gtagacgccg cccccgttgg
    11941 agaagtgcag ggcccgctcg acggtgtagg gcaggccttc gagggtgacg gccgcccgct
    12001 cggccaggtg gggcgccagg aacgcgggta actcgaccca ctccggagtc tggaacaccg
    12061 gcccccgcgg gtccggaacc agccggccgt ccggggcctc gatcgcggga acgagatcgc
    12121 cgcggtcgtc gtagcagtgc cgcagcgtga aactgccgta ccgcaggtgc acgggaccgc
    12181 cgttccagcg caggtcgctc aggatgtacg ggccgggctc gccggccagc agcgcgtcga
    12241 gctcctcggc gatgcgcccg cactgctcct cgtccgccgg gtagacggtg aggaacttgc
    12301 cgctcgcggc gcggtccgcg tacttcgcgt tgcgcaggtg caacaggtac cggctcggaa
    12361 cgaacttgaa ggcgatccgc cgctccacgc agtaccggta gacccgttcg aggaccgact
    12421 cggcgttgtc gaggcaggcc gagacatgga tcttccagcc ctgcgagggc agtcgggcgt
    12481 ccagggggcg cagcgccagc cagtccccgc tgcggtgcgt ctgccacccc gccggtacgg
    12541 gggcgagcgc ggccgggtag ttctcctcgg cccgccggta cggcgcgtcg tagaaccagc
    12601 ggtcggcgtc gcagaaggcc gcgtacccct tgttcactcc tgctccctcg gtcggtgacg
    12661 tgctcacgct gtcacgcggc ctgagggccg cgacagtcac ggctgtcact tccggggtgt
    12721 gcagtacgca cgagtcacaa cgggccgccc atgctctcgg tcagcgcgat cgccgcgacc
    12781 gggcggaaac aaaccgggcc cggaccgccg ggtcccgcgg gccgggtggg ggtggcgctc
    12841 gtaggctgaa gagggtgtac ggctcctgtc cggcagccgg tgggccgcgg gaaggtgagg
    12901 catgggaagg cgctgggccg cacgtctgtc actggccgcg ggtgtggcgg cgctgctggt
    12961 gctggtggtc ttcggcgggc tcgtcagcct cgtgctcatg ggcgtgggct gggcggggct
    13021 ggcgctctcg gctgcgggcg tgtggtggat gctcacccat accggccgga tccgggtgct
    13081 ggccgtgctg ctgctggtgg ccgtgccgct cgccgtgctc gccctgtacg ccgccgcagg
    13141 gctgctgtgg gtcgtgctgg tctcgctcgg cctgtgggcg ctggccgtct tcgcgggccg
    13201 ggccgcgctg gtcgaggacg ccccgccggc catgcccgag caccccgccc gcaggcccga
    13261 gcggccgttc ctgatcatga acccgcgctc gggaggcggg aaggtcacca agttccggct
    13321 cgcggagcgg gccagggccc tgggggcgga ggtcgtcgtg ctggatccgg accggccgca
    13381 ggacgtggtc cagctggcgc gggaggccgt ccggcgcggc gccgacctgc tcggcgtcgc
    13441 gggcggtgac gggacccagg ccctggtcgc cggggtggcc gtggcgcacg acctgccctt
    13501 cgtggtgatc agcgccggca cccgcaacca cttcgccctg gacctgggcc tggaccgcaa
    13561 gaaccccgcc cggtgcctgg aggcgctgac cgacggcgtc gaactgcgcg tcgacctggg
    13621 atacctccgg gcggggggtc ctgaggagcc cgaggagccg gcggagcccg gtacggaggc
    13681 cgtcttcgtc aacagtgcct cgttcggcgt gtacgcggag gtggtgcaga gccccgccta
    13741 ccgcgacgac aaggtccgca ccatcctgga gatgctgccc gacctgctgg cccaggagag
    13801 cggcgcgcgg ctgagcgtgc gtggcgacgg gccggtcctg gacgcccccc aggccgtcct
    13861 ggtgagcaac aacccctatc agcggggcga ctcggcggga ctcgggcgcc gggagcggct
    13921 ggacaccggc gagctggggg tgctgggcgt ccacgtcggc agcgccgccg aggcggcgga
    13981 gctcctgctg cgcggcgggc agcagggccg cgggctgacc gagaccaccg cccgggaggt
    14041 cgtcgtcgac gccgacgccc ccgtcatccc ggtcggtgtc gacggggagg ccctgacgct
    14101 gcccactccg gtccgctgcc gcctcgcgcc cggcgccctg cgcgtccgcg tgccccggca
    14161 ccggccgggc gtacggctgg gcgcgccgcc gatggactgg cgccgggtgc ggcggctggc
    14221 gctgaccatg ggccgggccg ctgcgggccg cggtcccgcc tgaccgggcg agagcggggg
    14281 aggggcggtc accgcgccgg agtccgcggc aggagcagcg cggccgcgag cccgacgagc
    14341 ccgatcacgg ccagcgcgat catcgcggcg gcgtaggcgc cggtggagag gcctgcgacg
    14401 agaatggtgc ccgcgaccgc cgtgccgagg gaggaaccga ggttcgacac gctgcgggag
    14461 aggccggaga tctcgccctg ctgctcttcg gggaagctcg actggacgac gttgaccgag
    14521 ggggtcagca tcacgccgag acccagtccg atcagcagga ggccgggcgt gagcgcccac
    14581 gggttcgggg agctgccggc cagcgcgatc aggacgacga tgccggcgag ggtggcgagg
    14641 aaacccgtca cgatcagggt ccgctggggc caccgctggg cgaggcgttc ggcggcgagc
    14701 gaggacacga gcaggccgag cgtggcggcg gtgaagatga caccggtctg gacggcgtcg
    14761 tagccgcgta cgacctggag gtaggccgcc acggtgaacg aggaccccat cagcagcagc
    14821 cactggacgt tctgcgtgac caggcccagg ttggacgtcc ggtcccggaa cagggccgtg
    14881 gacagcagcg gttccttgcc cgcccgctcc ttggcccgca cggagcggaa gaacccgagg
    14941 agcacgaggg cgcccagggc gagcagggcg agggtgagcc acaggctgtc gtcggccgcg
    15001 aggatgccca tgacgacgag gatcaggccg gcggcggaga ggaccgcgcc cgtggtgtcg
    15061 aaggagcggg tcggatcggg cggaagcgga tcctccaggc ggcggctcag caggatgatc
    15121 acggcgatga ccagggcctg gaagacgaag gcggcccgcc agctcagcgc cgaggtgatc
    15181 agcccgccga tgagcggccc ggcggccgcg ccgatgccgc ccagcgccat gatgacgccg
    15241 aaggcccggg cccgggaggc gaggtccgtg aagatcagcg tcgtgaggat gtagacgggc
    15301 gggatgagca gggccgtccc gatgccctcc aggatcgagt tcccgaggat cagtacgccc
    15361 aggcccgggg cggcggcgct cagcagcgcg ccgatgccgt agacgacgag gccgaccagg
    15421 aggcagcgct tgcggccgta gcggtcggtc agtttgccgc cggggatcat cagcgcggcc
    15481 atgaccagca ggaagatcgt gatggctgtc tgtaccccct ggacggtcgt gtccaggtcc
    15541 tcgctgatgt cgttgatcat cacgttcatg ttggagccgg cgaagctgca gatgaactgc
    15601 gcgagcgcca gcggcgcgag gacccgccgc tgcgcgccgg acggccggcg cggggttcgg
    15661 gtgtcggaca ccggtgtcgc ctccgcatct cgggccgccg ggcctgctgc gcggcggttc
    15721 gtacgcggtg ccgcccttgg cggtacgcac ccacgctcac agcgtgcgcc gtgccggggc
    15781 ggggcgcacg ccgagtgccc ggcacgcgtc cggaacggtc agctcgtcgt accggccttg
    15841 acccagccgt cgccgccgag ggggaactcg tagcccgggc gaccgcccag tccgctggta
    15901 cggaacggct tgccgttgtg gtcgatcgtg agggtgccgt ggcgggagcc gctggaccag
    15961 gacagctcca ggtaccagct cacgtcgtac ttggaggcgt cggccttgac gtagaacacc
    16021 tccggttcgg actcgctgac cttgaacggg aagtccggct ggtcgggcgc gggcacgacg
    16081 gccgggcgcg cggcgtcgag ggccacggtg aacgaccggg tcggtacgcc ggcgccgcag
    16141 ccgacacccg gatagcccat ggcgtagtcg ttccaggcga ggggcgcgtg cttgccgacc
    16201 gtacggacgg tcaggccgtc caggaccacc gtctccttgc cggagccctg gagggtgagc
    16261 gtgacgtact gctcgcccgc ggagacggcc cgggacgccg ccacccaggc gggcgcgtcc
    16321 cgttccaggg gcggcgggcc cacctcggac gggggcttct cgatcaggta gtgctggccg
    16381 cagggcgact cccaggtgta cggctgggcg gtcaccttca ccggggtccc ggacacggcg
    16441 ccgtcgccgg cgggggcccc gggcgcggac cccgaccccg acgcgggccc ggatctggct
    16501 ccggacccgg acggggccgg gggtgcggcg gtgccggcgc cggccccggc gggctcggag
    16561 gccgacgggg agggcgccga gggcgcgggg gaggccgtcc ggccgtccgc gcgcttcccc
    16621 gcgccgggcg cgggggacgc ggccgcggcg ggccggtcgc ggacgtcggc gtcccgtgac
    16681 gtcaggtgcg cggtgagggc tacggccccg atcgtcccgg ccacgacgcc cgccgcgatc
    16741 ccggcgagag cggccgcgcg cggacggcgc cgccgctccg ccgcggccgc cgagggcgcg
    16801 gtgtcggcgg gcgcgggctc ctgcgtcgca cccggcccgc tctcctgcgg agatggcgac
    16861 gacggagacg acggagacga cggcggtgtc gccggggcgg cggcggcccg tgccgggccc
    16921 tccgcttcac cggcgccccg gcgcgggcgg ttcgtgtccg ccagcaccca gttccggtgc
    16981 agttcgagga gttcctcggg cgaggccttg cagaggcggg cgaaccgctc gaccggtgcg
    17041 tactccgtcg ggacgacatc gcccgtgcag tagcggtgca gggtcgacgt actcatgtgg
    17101 agccgtttgg cgagcgttcc gtagctgagg ccggaccggt ccttcaactc ccgcagcagc
    17161 cgggcgaacc cggacccggc agtgtcctcc ggcaccgatc ctcctacccc cgtgtcccgt
    17221 ccggcgtccc aggaacgggt tgttccagca gctcagagcc cgtttcggcg tcccaccgtc
    17281 cctgaccgcc cccggcgggt ggcggctggg acggatcacc gcacaggctg aggccatcca
    17341 agcacaccgc tcacggcgac cggtcccgac cgtccgccgc agccacgtca catgaggggt
    17401 cctcagccat gtccgccttc cgcagcaccc ccgccacgag cacctcccgc gccacccttc
    17461 cccgcgccgc ccgccggctc ggcggcgcgg ccgcactcgc cctcgcggcc ctcgccctga
    17521 ccgcgtgcca ggacggcaag ggcctccagg acgagggagc cgcgaccttc tcggactccg
    17581 ccgtcgccac tccctcggcg acggccaccc cgggggccgg ctccggatcg gcctccggat
    17641 cggccacgaa gaccggttcc gccacgaagt ccggcggggc gaaggcgacc ggcggcgacg
    17701 cgaagggctc ctccgccccc tccgccgagg gcgaccgcgt cacctgcaac gggtccaaca
    17761 ccgccgtcac cgtccagacg gtctcccgtc cgctcaacca catgctgatc acggtgaaga
    17821 acaccggcaa gaagaactgc gacctcacgt actaccccgt gctccgcttc gacgagatgc
    17881 agtgggcgcc ggccgcgcgg aaggacaccc agccccaggc cgtggtcacc ctcgcacccg
    17941 gccggtccgg ctacgccggg gccctgctgt cggcggccga cggcagcggc gagggcgggg
    18001 tgaccggaca ccggctcacg atcgccttcc agggccggac gtcccacagc gacggcggcg
    18061 cgtccgccgt cccgtcgctg ccggcggcgg gcgtctacta cgacagctcg ttgacggtca
    18121 cctactggca gcagagcgcc tcggacgcac tcggctcatg agccgccgcc cggcagggtc
    18181 tcctggagcc agtcgaagac gacctcgcag tgcagctgcg gggccatggg ggagcagtgg
    18241 agctgggcgc cctgggccgc ggtcagcttc aggtagtcct tgggagaggt gagcgcgtcg
    18301 tacaactggc gcggctggcc ggggtagaac tgctcgtcct cgtagtccag gacgagggtg
    18361 ggcgccttga tccggctgac gacggaggcg atcgagagtg cctggatacg ggtggcgggg
    18421 gtgtagaagt cggtgaagag cttgccctgc cgggcctgga gcatcgccgg gatggagaag
    18481 ggctcgaagc gcttcttcag cacggcggcg gcctccggcg gcagctcggg aacgaccttc
    18541 gtgttccaga tgtcgttcgt ctcctccttg ctgggggtga ggatctcccg gatctcgggc
    18601 gggaagccca gccagggctc gacgcagccg ggcatggcca ccagcgcggc gatccggctc
    18661 tcgaaggccg ccgccctcgg cgcgaggtca cccgccatgc tcagaccggt cagggcgatc
    18721 ctgtcctggt ccacgtccgg gcgggcggac agccagtcga cgagggggct gacgaccttc
    18781 tcccaggtgg gggtgaacac cacccggtcg acgaagagca gctgcccctg ccccggaccg
    18841 tcgtagacga gggcgttcca gccgcgttcg agcgcggcgg ggaccccgta ggtccacatg
    18901 tcgacgttct ggccgtcgct gccgttggtc aggatcaccg tgggccgggg cgtgttcgac
    18961 gtgtcgggcc ggaagaacca caccggcaac ggcgtcgtgc cgtacgggac ggcggccttg
    19021 accggggcgg gctcgcaaag gtcgcagaag gcgtcccagg cgtcccgtcc cgccttgtac
    19081 agctgctcct cgctgcccgg gtccttggaa ccgaggacga agaacagcgc ctggccgtag
    19141 tactgggcgg cgcgcagcgc ccggaaccgt ttggtctggg cgtcggccgg tgagcccggc
    19201 ggcggcccca ggagctggtc gccgagcttg cggaaggtat cgacgtacgt ctgcgcggag
    19261 aggccggccc cgttgatcgc gttcacggcg gtgaggacct cgccgacctc ggcggcgccg
    19321 gcgccggagg ccccgagcgc gaggaggccg ttgaagttgt accccgggtc cttgaagagc
    19381 gtcatcgcac cgggggtggg gccggtcgcg gccgcgaggc cggagggagc ggagccgctg
    19441 ggggtgggcg ccggggcgcc gggggtgcct ccgggagcgc agccggcggc gagcgccgcc
    19501 ccggcgccgg cgacgagcag ggcgcggcgg gtaggaccgg actcccggtc gcctgatatg
    19561 tacgtcatat cagtggaacg tagccctggt ccggtacacc cacattccga cctgctccga
    19621 acggcttacg gcctacggct tgtggcttgc cgtcggcggc ggtcagtagc ggggctcgtc
    19681 cggtgggcgg gggtggagcc ggtcgcgctc ccggccggag cgctccgcgt ccccggcggc
    19741 gcggatgtgg ctcaggtgcc accggctctg ctgggtcatc agcgagccga gcgggtgggt
    19801 cgcggtggcc gggttcgcca gacacagctc gtagcagcgg gccgccgggt cgggcgccgc
    19861 gaagtcggtc cggtacagct cggcgctgcg gaactgggcg tacgggtggc cgagttccgc
    19921 ggcggcggcg aacagctcca gggcgtgcgc cacgggagcc ccggtgagcg gcagcagccg
    19981 ttccaggtac atctcgccga gcgccagcat ggcctccggc tcgccgagcc gggcggcctc
    20041 gcggtaccag tgcgcggcgt ccgcgtagga ggcggtgatg ccggccggcg ggcagccgtc
    20101 gtaggagagc cggccgaggt agtgggcggc ccgccgggag gtgccggcgc tgccgcgcag
    20161 ccagggcgcc gccgcggcgt actcgccccg ggagaacagg acgtgcccga ggagttcggc
    20221 cgcctcggcg tgaccggcgc gggccgcggg ttcgaggaag aacgcggcgg cctcccggtg
    20281 ccgcggatcc tgccagcagt ggagcccgat ccggtggaac tcctccgccg tggtgggctc
    20341 ccgcccgtcc acggtgaagt cgacgccgtt ccacctcacc ccgtcccgcc cccgtccccg
    20401 cggcgcgcgc cgctccgtac ccgtggtccc cgccgccggt tcgcgggccc gcccccgttt
    20461 accgtacgcg gcagcggcca catgcgggcc atgaccgaac cggagaagag ggcccccgac
    20521 cggccttccg cgccggcgaa ccggcctcgt gcggtggccg cgcggctcga ctggacgggc
    20581 aggcgaacgt tttgtccggg accctcaggg taggcgccgt ttcgtccgca gtcatccagt
    20641 cgaacaatca agcaacaccg aggaatggag acgtcgtgtc cgtcgtcaag aacgccctcc
    20701 cggaagccga cctgaaggtc gtcggcgaag cgctccaggg cgctctggtg gacctggtgg
    20761 acctgggcct cgtcgccaag caggtccact ggaacgtggt cggcccccgc ttccggtccg
    20821 tgcacctcca gctggacgag gtcgtcacct cggcgcgcac ccactccgac gtggtcgccg
    20881 aacgtgcctc cgccctcggg atcaccccgg acggccgggc cgcgacggtg gcgtcgtcga
    20941 gcgcgatcag cggggtgccg gagggctggg tgaaggacgt ggacgcggta cgcatcctcg
    21001 tcgacggcct cagcgcggtg atcacccgca tgcgcgaacg catccaggcc accgcggacc
    21061 ccgacccggt cacccaggac atcctcatca cggtgaccgg cgacctcgaa aagcaccact
    21121 ggatgttcgc cgccgagagc gcctgagcgg gcgccggggg gtgggcgcgg gcggctacgg
    21181 gaggatggag tccacgtagc cgccgtccac tcgcagggcg ccgcccgtgg tcgcggaggc
    21241 gaagggggag gacaggtaga ccaccatgtg ggcgatctcc tccggctcga tcagccgctg
    21301 gagcagcgac tgggggcggt gcgtgcgcat gaacgcgcgt tgcgcctcgt cccacggcag
    21361 gttccggtcg accagttcgt agacgaagtc ctcgacgccg ccggtgtgcg tcgggccggc
    21421 gatgacggag ttcacggtca cgcccgtgcc cgcggcctcc ttggcgaagc cccgggacac
    21481 ggcgagcagg gccgtcttgg acatcccgta atggatcatc tcggcgggga cggccaccgc
    21541 cgagtcgctg gcgatgttct ggacgcggcc ccaggagcgc tccatcatgc ccgggaggta
    21601 ccgccggatc atccggacgg cggtgagcac gttcgtatcg aagtagcggc gccattcgtc
    21661 gtcttcgatc tccagcgcct tcgccggtcc gaagaccccg aggctgttga cgaggatgtc
    21721 ggtccggggg accgcctcga agacggaccg cgcgccctcg tccgtcgtga tgtcgccggg
    21781 cgccgcgacg aactcgccgc ccgacgcgcg gaggcgggcc agcgcctcct ccacggatgc
    21841 tcggctgcgg ccgttgacgg ccacccgggc gcccgcggcg gccaggccgg cggcgatggc
    21901 cgcgccgatc ccctgtgtgg agccggtgac cagggccgtc ctgccggaga ggtcgatgag
    21961 cacgcgatac ccgcctcgtc tgccgccgcg cggcccgtcg ggtccgccgt cctcgtcacg
    22021 ggttccccgt atcggcggat tcctcacctt ccgcccggga gacggccctc accgcggctg
    22081 cccttgccgg gcccggctcc gtcactatgg gggcgtgcac cgcttccgct tcccgcgcta
    22141 cctgctcata tgggtgtcct gtacggccgc cagcgtgacc gccgtcatgg ccaccgtcga
    22201 cttcgtggcg ggctcgacac ggccgaaacc gccggtcgcc cggtcggcgc cgaccgtgtt
    22261 cctctcaccc agtgcctcgg cttccccttc ggcttccgtt tccggttccg gctcgccctc
    22321 cgcctccgcg agcccttccg cgtcgccctc ggcctccagc ccgcaggtct ccactcccgc
    22381 ggccgcctcc cgtccgccga cgcgggcgcc cggcccctcc ccctcaccgg ccggcacacc
    22441 ccgtaccacc ccggtccagg gctgcggtgg cggcggggca gggtcgcaca ccgtcccgtc
    22501 gacgggcggc aaggcgaccg tgcggtacgg gagcgacaag gtgtgcctga tctccgcggt
    22561 cccggcgctc ggcttcaagg tgagcaccgc ccagaacgcg gaccacacgc tcaccgtcac
    22621 gttcaccggc agcggtc
//
