LOCUS       NZ_JAQESL010000043     12062 bp    DNA     linear   CON 29-FEB-2024
DEFINITION  Coprococcus sp. AM97-35 AM97-35.Scaf43, whole genome shotgun
            sequence.
ACCESSION   NZ_JAQESL010000043
VERSION     NZ_JAQESL010000043.1
KEYWORDS    WGS; RefSeq.
SOURCE      Coprococcus sp. AM97-35
  ORGANISM  Coprococcus sp. AM97-35
            Bacteria; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae;
            Coprococcus.
REFERENCE   1  (bases 1 to 12062)
  AUTHORS   Lin,X., Hu,T., Chen,J., Liang,H., Zhou,J., Wu,Z., Ye,C., Jin,X.,
            Xu,X., Zhang,W., Jing,X., Yang,T., Wang,J., Yang,H., Kristiansen,K.,
            Xiao,L. and Zou,Y.
  TITLE     The genomic landscape of reference genomes of cultivated human gut
            bacteria
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12062)
  AUTHORS   Zou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-NOV-2022) BGI Reaserch, BGI-Shenzhen, Beishan
            Industrial Zone, Shenzhen 518083, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. v2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: MGI
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/29/2024 10:49:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,361
            CDSs (total)                      :: 3,321
            Genes (coding)                    :: 3,266
            CDSs (with protein)               :: 3,266
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 6 of 55
            Pseudo Genes (incomplete)         :: 54 of 55
            Pseudo Genes (internal stop)      :: 2 of 55
            Pseudo Genes (multiple problems)  :: 5 of 55
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:11:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 12062
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAQESL010000043.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     gene            complement(<1..>215)
                     /locus_tag="PG840_RS15950"
                     /pseudo=""
     CDS             complement(<1..215)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015526860.1"
                     /locus_tag="PG840_RS15950"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="RNA-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MEGNTSKENLKSCRVQGKYAGTVEDIHKGTVFVRLELGVNAIAHS
                     CYDSRTVGKKDKVSFVVTHIDEERNV"
     CDS_motif       complement(87..215)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MEGNTSKENLKSCRVQGKYAGTVEDIHKGTVFVRLELGVNAIA"
                     /locus_tag="PG840_RS15950_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(3..86)
                     /prepeptide="core"
                     /locus_tag="PG840_RS15950_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.00"
                     /molecular_weight="3159.5"
                     /monoisotopic_mass="3157.6"
                     /core_sequence="HSCYDSRTVGKKDKVSFVVTHIDEERNV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEGNTSKENLKSCRVQGKYAGTVEDIHKGTVFVRLELGVNA
                     IA"
                     /leader_location="[86:215](-)"
                     /alternative_weights="3177.5"
                     /alternative_weights="3195.5"
                     /alternative_weights="3213.5"
                     /alternative_weights="3231.5"
     source          1..12062
                     /collection_date="2014-02-01"
                     /country="China: Shenzhen"
                     /db_xref="taxon:2997953"
                     /host="Homo sapiens"
                     /isolation_source="fecal material [ENVO:00002003]"
                     /lat_lon="22.32 N 114.05 E"
                     /mol_type="genomic DNA"
                     /organism="Coprococcus sp. AM97-35"
                     /strain="AM97-35"
                     /submitter_seqid="AM97-35.Scaf43"
     region          1..12062
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..12062
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12062
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5322:8460](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5323..8460
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            463..1152
                     /locus_tag="PG840_RS15955"
     CDS             463..1152
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728879.1"
                     /locus_tag="PG840_RS15955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_025580962.1"
                     /transl_table=11
                     /translation="MRKDIIIIDDDRDLCTLLQESLLQENICADISCNGFDGIKSVKDK
                     EYQLVVLDVMMPGISGFEVLERIRDMSNVPILMLTAKDDSTSKVKGLRAGADDYLTKPF
                     EMEEFFARVLSLIRRYTRLNNMASKAILKYGDLRIDLESGIVELSGEELKLSAKEYDVL
                     IYLAKNQGKILTKKQIYENVWNEEYVYDDDNIMAVISRLRKKIERTAENSYIQTVRGLG
                     YRFNKEL"
     gene            1158..2075
                     /locus_tag="PG840_RS15960"
     CDS             1158..2075
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="PG840_RS15960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_117843973.1"
                     /transl_table=11
                     /translation="MKLFYVVLVILLFYNLGLTLYVFKINRRLKEFNQILLEIEKGQSK
                     QKFLLKKNNRIDQVGFRVNSILYKYEKRIEESNIELEANKQLMTSLSHDVRTPMTTLIG
                     YLDALDLKLVSSDKEEQYLRLAKEKAYDLKKYIEVLFEWFRINSDEEQLEIKAVDITEE
                     TRRIFLDWIPIIEEHRIGYNIEIPEKAIIVEIDEDCYMRAINNIVQNIFTHSKAANISI
                     TASEGNGKFRLEIGDDGIGIAKEDLNYIFERLYRCNKGRSGKGNGLGLNISKLLLEKMG
                     GTISAFSEPGKGTVFCIEFSVIQR"
     CDS             2084..2182
                     /gene="allorf_02084_02182"
                     /locus_tag="allorf_02084_02182"
                     /protein_id="allorf_02084_02182"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MIRSSIIFFVLNKLQGSCQVSVRFLSEKYIIL"
     CDS_motif       2084..2134
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MIRSSIIFFVLNKLQGS"
                     /locus_tag="allorf_02084_02182_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       2135..2182
                     /prepeptide="core"
                     /locus_tag="allorf_02084_02182_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.20"
                     /molecular_weight="1762.1"
                     /monoisotopic_mass="1761.0"
                     /core_sequence="CQVSVRFLSEKYIIL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MIRSSIIFFVLNKLQGS"
                     /leader_location="[2083:2134](+)"
                     /alternative_weights="1780.1"
     gene            2215..3138
                     /locus_tag="PG840_RS15965"
     CDS             2215..3138
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016281052.1"
                     /locus_tag="PG840_RS15965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_055151469.1"
                     /transl_table=11
                     /translation="MSQYIIQTRDLTKTYGEQKSVSNLNMHVRKGKIYGLLGRNGAGKT
                     TTMKMLLNLIEPTSGSIRIFNRDIRLEEKKILPRIGSLIESPGFYPNLTGTENLRIFAK
                     LRGIPRTDAIEQALKLVNLPYKDKKLYSQYSLGMKQRLAIALAVMHDPEILILDEPING
                     LDPIGIAEIRTFIEDLSKNRGKTILISSHILSEIAVLADDIGIIDKGVLIEEGSMKELE
                     EKNGKYIHFKVSDNAQAARILSVYYKESNFKVSGNQDINVYNLSISIPDIVRSFVQEGV
                     DVMDAHLCEDTLEDYFKKVTGGEGIA"
     gene            3131..3940
                     /locus_tag="PG840_RS15970"
     CDS             3131..3940
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728877.1"
                     /locus_tag="PG840_RS15970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_117843974.1"
                     /transl_table=11
                     /translation="MLDLVRCEFTKLKRRKITLMLIVLSCFFPLIVVMTTKNGMSGDLS
                     THYLKMRFDLSFTMTQGYGLVFLAPCLIGMLATILFFMERDNDTFKNIRTVPVTITKMI
                     LAKICVLFIYGTLFSLASVSFTIFFSWILKVGIIYDLAYKLGFSIIFGLVITIASLPIV
                     VIIVYFNKSYLVSTLLAFFYSILNWGIIGLFETMAVKGTAKFLNLFPVICAMDWTSGKL
                     VDHVIKDNLSKEAYIMFPSDIYAFLVLGVTLFLSLMLMIRFYKKWTR"
     gene            3946..4731
                     /locus_tag="PG840_RS15975"
     CDS             3946..4731
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574362.1"
                     /locus_tag="PG840_RS15975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_117843975.1"
                     /transl_table=11
                     /translation="MGNIISTELLKIKRYSVVKAGLVMMSLSVLMSCFYSIASTNKVWD
                     FQYFIQQVIISNCTLFFPIIITLVAVYIISRETTDDTLKSILTVPISYKKLLIAKFWLL
                     LFLTIVFSIFNALLSICFNAFLGFSGMNIHMMLMSAAQIIVSDILVYISVLPIIIVCAF
                     AEGKSLLGVAVAFIYGYFATMEGSMLNWFPIKAAMILVDPKCGSEYGITYKIPPAAMSI
                     IGVLVVSILLFQMLNRTKKNVYMKSKRKVKVKQTRRKGW"
     gene            5006..5206
                     /locus_tag="PG840_RS15980"
     CDS             5006..5206
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="PG840_RS15980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_025580957.1"
                     /transl_table=11
                     /translation="MKKNYRNPMTRPENFMNPAGNVMKEIKEADLNNFSAGAGEPRVSD
                     GSQFCTSTKECNWGTIMFVCC"
     CDS_motif       5006..5146
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MKKNYRNPMTRPENFMNPAGNVMKEIKEADLNNFSAGAGEPRVSDGS"
                     /locus_tag="PG840_RS15980_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       5147..5206
                     /prepeptide="core"
                     /locus_tag="PG840_RS15980_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.40"
                     /molecular_weight="2129.5"
                     /monoisotopic_mass="2127.9"
                     /core_sequence="QFCTSTKECNWGTIMFVCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKNYRNPMTRPENFMNPAGNVMKEIKEADLNNFSAGAGEP
                     RVSDGS"
                     /leader_location="[5005:5146](+)"
     gene            5323..8460
                     /locus_tag="PG840_RS15985"
     CDS             5323..8460
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="PG840_RS15985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_173684412.1"
                     /sec_met_domain="DUF4135 (E-value: 1e-104, bitscore: 340.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.3e-58, bitscore:
                     187.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNNCDNNSYFYERNYYKDVPIKDTQILEYWNNILGKDVIESID
                     KAYGVSIEQILFSEYSLNHKYISFATLNQEYSDMCNEKAISYLTKKGTKVLFDQFVLRF
                     LGYGKRVLERKSRKGYIVKVIQDCFLKNLAERILDVSLSTLIFEMYLAKEQGELRGNDE
                     AEEYNDYNQRFLGNDKYIKELFSIYPGLKRMLIELMENLANNYILLQERMEKDTLLLED
                     KFGGKKSWTEVKDIRTSGSDSHKKGNSVFLIQFQDGTKIVYKPHGLKVEKAYQSFLEFI
                     SSNCKKDFRQFLILDCGDYGWEEFVVNLPCNSEAEVRNYYYRIGVLVFCNYILNVNDIH
                     TENLIANGGYPVVVDAETVLDNKRDKKKKSGREKIYDKIHESVLYSGVLPFYKYTKNGK
                     GINMSALNGQEGEQYPILIPRLKNAGTSNMHYEYERPITQASNNLLRLGEKVKEPNQYI
                     DEICEGFFDAYTFCLDNKKLILNYVSIFENIEVRHLVQDTQRYSMLLHTSYNPDFLQDA
                     KDRQLFLCAVLKNVEQMQGNMEIAKLEIKDMLNMDIPYFYSNTSKEDLYGSEGEVVKNY
                     FAESSIQHLRNKICSMGKKDREEQIRFIKIILTDLNDVKVEKPKKDINELCISRSDNEH
                     GQKEYKKNAILKILHTLEQKAFYGDDGQDINWIGITSIGNSENSSWNIQPLGVYLYEGL
                     GGIALFYNALQQSDFDVDLSAACKAFETMMFQYTDDMLERSTDLEKESSGAYAGEASVI
                     YVYEVLYKITGKQKYLEYAEKHCKILEYALKADENNDLIYGNAGAVIVLLNLYHLAQKD
                     IYLQLACEAGNILIKNQNKGKWCCGNGQSLSGLSHGITGIIYALTKLNNEQFHIEYQKA
                     IHSGLIYENTMYSDKYNNWLDNREEAKKEENSDNRCMAAWCHGAPGILLARSKMYNLVK
                     DSSDYITVQCDIERALFATKMYGFTDNDCLCHGNLGNTEILLEYSKECNDEEVRHMMLS
                     ARTQIAMDIINENYDCARSYLHGYKIPGFMTGISGMGYSLLRDLYPELPCILALEI"
     gene            8503..10599
                     /locus_tag="PG840_RS15990"
     CDS             8503..10599
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="PG840_RS15990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_025580955.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.5e-31, bitscore:
                     97.2, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQKKVHYVSQLGSMDCGIACLTMILNYYGCKSDIVDIGAEIQIG
                     RDGMTLAQMKELAEKYGFKFAAYQYNHEEKNLIEYLPAILCNDSHYVVVDKTKKKGKYI
                     LFDPANGKRVVDFLELKNGYKDILVSVIPSRNIKKIKKTKFKIEVKFSQFMIAIMLMLM
                     CQLITLAVPMVVQKVIDSLSSAHITIHIWKITLLVLLIMCAHFVLSLLRQKILLNINMK
                     LFKTMISNMIHKIFRLDVSFFEWHSAGDIGNRFNSINQLNDILTNGFINIIIQGITSLV
                     CLAVMTSISPYLTAFVLVVSIIQIAIMILLNGKNLIKTKEYIYSQSTIQGELIDTLENI
                     MEIKCMGMDNAVKSNLQNSYSKLIERFKGKTRISNLMNSFSSTLNLIFPLMIYVIGSYS
                     VKQGGLTIGQLIAYATLVGYFTAPFTTVVLLLPSINSIKEVLLRYKELMIFRENYHTGV
                     LVPGKFENLKISSVSYCYNSGQAYALNNVSLDLRRGERIAIVGLSGSGKSTLIKAILGA
                     VDINQGCIEINNYDIRSMSKEQIYKWFSVVTQNPMCLNASIRKNIDIIGDAPDEKIWKV
                     LDIVALKEEVLSMPLGLDTLVGEGGQNISGGQKQRIAIARALLSDTEVVIFDEATSNLD
                     QLTEKKIYDNLRSTNKTQIIITHRLSSIRDTDYIYVLNRGSIIEQGTHLDLMKKKGWYF
                     ESIQ"
     gene            10654..11319
                     /locus_tag="PG840_RS15995"
     CDS             10654..11319
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PG840_RS15995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_025580954.1"
                     /transl_table=11
                     /translation="MKKKEIVIGVSVLISASLPISVYAASNESMSSRGFIIDETNEFED
                     IVKQILDVKSKHPEWSEQQISDFMDQIHAIKKDGVIDIWNALTSSEKKLVIRYPFDALK
                     VNKAKEIATKQTERKFGKNGLGDRSDAFRHGIWNAEMTVLIGSEKAELFATAHEDKDTT
                     GNESDGYTKDEHKKMDLHNNEIGRKLGADNLSAPEEKMAEIIYDEIMREDSLFVWLHE"
     misc_feature    11823..11837
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 18.55"
                     /tool="antismash"
ORIGIN
        1 gcaacattcc gttcttcatc aatatgtgtc acaacaaagg acaccttatc tttcttccca
       61 acggtgcggc tgtcgtagca actgtgagca atggcgttga cgcccaattc taaccggaca
      121 aaaacagttc ctttgtggat gtcttccacc gttccggcat attttccctg tacccgacaa
      181 cttttcagat tttctttgct ggtgttgcct tccacgaatg ttcccctacc tggaatcgtt
      241 gtcagattat tctagtatgg gtgaattttt tttaattgta gaggtttgtc aagttgagat
      301 gaagaaataa aaatttgata tataaagagt tagccaaaat ggttcgatat atgaattaca
      361 agaatattgt aagatacaaa cggttaatat agtgataaaa taattaccaa tataattgtt
      421 gcaatcaatt tgaagagata tacatattac tggaggcttg agatgagaaa agatattata
      481 attattgatg atgataggga tttatgtaca ctcttgcaag agagtctttt gcaagaaaat
      541 atttgtgcag atatttcatg caacggtttt gatgggataa aatcagtaaa agataaggaa
      601 tatcaattag ttgtattgga tgtgatgatg ccaggaatca gtggttttga agttttagaa
      661 agaatacgag acatgagtaa tgtaccaata ctaatgctta cagcgaaaga tgacagcacc
      721 tcaaaagtaa aagggttgcg ggcgggagct gatgattatt tgacaaaacc ttttgaaatg
      781 gaagagtttt ttgcaagagt attatctcta ataagacgtt acacacgttt aaataatatg
      841 gctagtaaag caattttgaa atatggcgat ttaagaattg acttagaaag tggcatagta
      901 gaattgtctg gtgaagagct taaattatct gcaaaagaat atgatgtact tatatatctt
      961 gcaaaaaatc aaggaaaaat tctcacgaag aaacaaatat acgaaaatgt ttggaacgaa
     1021 gagtatgtat atgatgatga taacataatg gcagttatta gcagattgag aaagaaaata
     1081 gagcgaacag cagaaaattc gtatattcag actgtaagag gtcttggata tagattcaat
     1141 aaggagttat gagataaatg aaattatttt atgtggtgct agtcatactt ttattttata
     1201 atttgggatt gacactttat gtgtttaaaa ttaatagaag actaaaagag ttcaatcaaa
     1261 tacttttaga aatagagaaa ggtcaaagca aacaaaagtt tctattgaaa aaaaataata
     1321 ggatagatca agttggattt agagtaaatt ctatattgta taaatatgaa aaaaggatcg
     1381 aagagagtaa catagagttg gaagcaaata agcaactcat gacaagttta tcacatgatg
     1441 tcagaacacc catgacaacc ttaatagggt atttggacgc tctagattta aaactggtaa
     1501 gttcagataa agaggaacaa tatctaagac tagcgaaaga aaaggcgtat gacttaaaaa
     1561 aatatatcga agtgttattc gagtggttta ggattaattc agatgaggaa cagttggaaa
     1621 taaaagcagt tgacattact gaagaaacca gaaggatttt tttggattgg atccctataa
     1681 tagaagaaca tcgaatagga tataatatag aaattcctga gaaagctata attgttgaga
     1741 ttgatgagga ttgttatatg agggctataa ataatattgt gcagaatatt tttactcata
     1801 gcaaagcagc aaacatatca ataacagcat cagaggggaa tggtaaattt agactcgaga
     1861 taggtgatga tgggataggg atagcaaagg aagatttgaa ttatattttt gaaagattat
     1921 accggtgtaa taaaggaaga tccggaaaag ggaatggact gggattaaat atttcaaaat
     1981 tattgctaga gaaaatgggt gggacaatta gtgcatttag tgaaccgggt aaaggaacag
     2041 tattttgtat tgaattttca gttatacaaa ggtaacaaaa aagatgatac gttcgagtat
     2101 catctttttc gtattaaata aattacaagg ttcttgtcag gtttctgtca ggttcctgtc
     2161 agaaaaatat attatactgt aaaacataga agattctgaa aggagaaaaa ccaaatgtca
     2221 caatacatta tacaaacacg tgatttaact aaaacatatg gagaacagaa aagtgtttcc
     2281 aatctaaata tgcatgtaag aaagggaaag atatatggac ttttagggag aaatggagct
     2341 ggaaaaacca caactatgaa aatgctgcta aacctcatag aaccgacatc aggttccata
     2401 cgtattttta atagagatat aaggcttgaa gagaaaaaaa tattacctcg aataggatca
     2461 ctgattgaaa gtcctggatt ttaccctaat ttgacaggta cggaaaatct tagaattttt
     2521 gcgaaattga gaggaatccc aagaactgat gctatcgaac aggcattaaa acttgttaat
     2581 ttaccatata aagataaaaa gttatattcg cagtattcat taggaatgaa acagcgatta
     2641 gctatagcat tagcggtaat gcatgatcca gaaatattaa ttttggatga accaattaat
     2701 ggcttagatc cgataggaat cgcagaaata agaacattta tagaagattt atctaaaaat
     2761 agagggaaaa ctatattgat ctctagccat atactttcag aaattgctgt tttagcagac
     2821 gatattggta tcattgataa aggcgtactc attgaagagg gaagtatgaa ggaattagaa
     2881 gaaaaaaatg gaaaatatat acacttcaag gtttctgata atgcccaagc agcaagaata
     2941 ctgtcagtgt attataaaga atcaaatttt aaggtatcag gaaaccaaga tataaatgtg
     3001 tataatctca gtatatcaat accagatata gttcgttcct ttgttcaaga aggagtagac
     3061 gtgatggacg ctcatttgtg tgaagatact ttagaggact attttaaaaa agtgacagga
     3121 ggggaaggaa ttgcttgatt tagtcagatg tgagtttaca aaattgaaaa gaaggaaaat
     3181 cacgctcatg ctgattgtat tatcatgttt tttcccctta attgtggtta tgacaactaa
     3241 gaacgggatg tctggtgatc tgagcacaca ttatttgaaa atgaggtttg atttatcctt
     3301 tactatgaca cagggctatg gtcttgtatt ccttgcacct tgtttaatag gaatgcttgc
     3361 gacaatcttg ttctttatgg aacgagataa tgatacattt aaaaatatta gaacagtgcc
     3421 cgtgacaatt accaaaatga tccttgcaaa gatctgtgta ctttttatat atggtactct
     3481 ttttagcctg gcgagtgtat catttacaat attcttttca tggatattga aggttggtat
     3541 tatatatgat ttagcataca agctaggatt tagtattata tttgggcttg tgataacgat
     3601 agcgtcactt cctattgtgg ttataatagt atattttaat aaatcctatt tagtgtctac
     3661 attgttggca tttttttatt cgattctaaa ttggggaatt atcggtttat ttgaaacaat
     3721 ggcagtgaaa ggtaccgcaa aatttctaaa tctatttcca gttatatgtg cgatggactg
     3781 gacaagcggt aaactggtag atcatgtaat aaaagataat ttgtcaaaag aagcatatat
     3841 tatgtttccg tcagatattt atgcattttt ggtattagga gtaacattgt tcttatcttt
     3901 aatgcttatg attagatttt ataaaaaatg gacgaggtaa tttaaatggg aaatattata
     3961 tcaacagagt tattaaaaat taaaagatat tcagttgtaa aagctggatt agttatgatg
     4021 tcgctatctg tgttaatgag ttgcttttat tcaattgcaa gcacaaataa agtatgggat
     4081 tttcagtatt ttatacagca ggtaattatt agtaattgta cattattttt cccgattatt
     4141 attacattag tcgctgtgta cattatttcc agggaaacaa cagatgatac attaaaatct
     4201 attttaacag tacctatttc atataaaaag ttacttattg ctaaattttg gctgctttta
     4261 tttttaacta tagtttttag tatttttaac gctcttttgt caatatgttt taatgctttt
     4321 ttaggatttt ctggaatgaa tattcatatg atgctgatgt cagccgctca gattattgta
     4381 tctgacatat tggtgtatat atcagtactt cccattatta ttgtttgtgc ttttgcagaa
     4441 ggaaaatcat tgctgggagt tgccgttgca ttcatctacg gatattttgc aacaatggaa
     4501 ggaagtatgc ttaattggtt tccaatcaag gctgcaatga tacttgttga tcctaaatgc
     4561 ggaagcgaat atggaataac atataaaatt cctcctgcgg cgatgtctat aattggggtt
     4621 ttggtggttt ccatactatt gtttcaaatg ctaaacagaa ccaaaaagaa tgtttatatg
     4681 aaatcaaaaa gaaaagtaaa ggtaaaacaa acaagacgga aagggtggta aaaaatggtg
     4741 gattgaatgt aaagaaatgt tgtccgtaat cataaacaat tttaatatat gtttgtaagg
     4801 aaggagaaga gaaaatacat actgctagtc aagtgaactt aacagaacct tttaaggaaa
     4861 tgagaaatga aaaaataaat atcttaggat gaacctgaag ggttctgtat tcctgcagta
     4921 ttttgtgaaa aattaaatcg tatagatata gacattttga atttacatat ggtatctatg
     4981 caagaagcag ttaggagcgt gccttatgaa gaaaaattat agaaatccaa tgacaagacc
     5041 agaaaatttc atgaatccgg caggaaatgt aatgaaggaa attaaagagg cggatttaaa
     5101 caatttttcc gcaggtgctg gtgaaccaag agtttccgat gggtctcagt tctgtacatc
     5161 aacaaaagaa tgtaactggg gaacaattat gtttgtttgc tgttagttta tgagagtggt
     5221 atgaaaccac aggtatgatg actactgaat gaataggttt ggcttctatg catagatatc
     5281 atatgcaaat tcaaaatttt ttacataatg gaggagatta ttatggataa aaataattgt
     5341 gacaataatt cctattttta tgaaagaaat tattataagg atgttccaat caaagatact
     5401 caaatattag aatattggaa taacatttta ggtaaagatg ttattgaatc aatagataag
     5461 gcttatgggg tttctataga gcagatatta ttttcagagt attcgttaaa tcataaatat
     5521 attagctttg caacgttaaa tcaggaatat tctgatatgt gtaatgagaa ggctatatcc
     5581 tatttgacta aaaaagggac aaaagtatta tttgatcaat ttgttctcag gtttctggga
     5641 tatgggaaac gggttttaga aagaaagagt agaaaaggat atattgttaa agtaattcag
     5701 gactgttttt tgaaaaattt agcggaaagg attttagatg tttctttaag cactcttatt
     5761 tttgaaatgt atttagcaaa agaacaagga gaacttagag gaaatgatga agcagaagaa
     5821 tataacgact ataatcagag atttcttggt aatgataagt atataaaaga attattttcc
     5881 atatatccag gtcttaaaag aatgctgata gaattaatgg aaaatttggc aaataattat
     5941 atattattgc aggaaagaat ggaaaaggat actttacttt tagaagataa atttggtggg
     6001 aaaaagagct ggactgaagt aaaagatata agaacgagtg gttcagattc acataagaaa
     6061 ggaaatagtg tttttttaat tcagtttcaa gatggaacaa aaatagttta taaaccacac
     6121 ggactgaagg tggagaaagc atatcagtca tttttggaat ttatttcttc caattgtaaa
     6181 aaggacttta ggcaattttt gattctggat tgtggggact atggatggga agaatttgta
     6241 gttaatcttc cttgtaacag tgaggctgaa gtcaggaatt attattatcg gataggagtg
     6301 cttgtttttt gcaattatat attaaatgtc aatgatatac atactgaaaa tcttattgct
     6361 aatgggggat atccggttgt tgtagatgcc gagactgtct tagataataa aagggacaaa
     6421 aagaaaaaat caggtagaga aaaaatttac gataagatac atgaatcagt gttgtattct
     6481 ggagtactgc ctttttataa atacactaaa aatggaaaag gtataaatat gagtgctctt
     6541 aatggccaag agggagagca atatccaata ctgattccaa gattaaaaaa tgctgggaca
     6601 tcaaatatgc attatgaata tgaaagacct attactcaag ctagtaataa tttactgaga
     6661 ctgggggaaa aggtaaaaga acctaatcag tatatagatg agatatgcga aggttttttt
     6721 gacgcatata cattttgttt ggacaataag aagcttatat taaactatgt ttcgatattt
     6781 gaaaatattg aagttaggca tttagtccaa gatactcagc ggtattccat gctattgcac
     6841 acatcataca atccggattt tcttcaagat gcgaaagata ggcaactatt tttgtgtgca
     6901 gtgttaaaaa atgtggaaca gatgcaaggg aatatggaaa ttgcaaaact ggaaataaag
     6961 gatatgctga atatggatat tccatatttt tatagcaata cttcaaaaga agatctttat
     7021 ggatcagaag gggaagtggt gaagaactat tttgctgagt ctagtattca acatcttaga
     7081 aataagatct gttctatggg caagaaagat agagaagaac agattagatt tataaaaata
     7141 attttaacag atttgaatga tgtaaaagtt gagaaaccta aaaaagatat aaatgaactt
     7201 tgtataagta gaagcgataa tgaacatgga caaaaggaat ataaaaaaaa tgccatatta
     7261 aaaattttac atacattaga gcaaaaagct ttttatggtg atgatgggca ggatataaat
     7321 tggataggaa taacatctat tggaaattct gaaaattctt cttggaatat ccaaccatta
     7381 ggggtttatt tatatgaagg attaggagga attgcccttt tttataatgc actacagcaa
     7441 tcagattttg atgtggattt gtcagcagcc tgcaaagcat ttgagaccat gatgtttcaa
     7501 tataccgatg atatgttgga acgatccacg gatttagaaa aggaaagtag cggtgcttat
     7561 gcgggggaag cttctgttat atatgtatac gaagttttat ataagataac aggaaaacaa
     7621 aaatatttag aatatgcaga aaaacattgc aaaattttag agtatgcatt gaaagcagat
     7681 gaaaataatg atctgattta tggtaatgca ggtgccgtta ttgttcttct taatctttat
     7741 cacttagctc aaaaggatat atatttgcaa ttggcgtgcg aagcagggaa cattcttata
     7801 aaaaatcaga ataagggtaa gtggtgctgc ggaaacgggc agagcttatc tgggctgtca
     7861 catggaatta caggtataat ttatgctctt acaaagttaa ataatgagca atttcatatt
     7921 gaatatcaaa aggcaataca ctctggatta atatatgaaa ataccatgta ttctgataaa
     7981 tataataatt ggttagacaa tcgggaggag gcaaaaaaag aagaaaactc tgataataga
     8041 tgcatggcag catggtgtca tggggcacca gggattttat tggcaagaag taagatgtat
     8101 aacctggtta aagacagtag tgattatata acagtacaat gtgatattga acgtgcacta
     8161 tttgcgacaa aaatgtatgg atttacagat aatgactgtc tatgtcatgg gaatttgggg
     8221 aatacagaaa tattacttga atattcaaaa gaatgtaatg atgaagaagt aagacatatg
     8281 atgttgtctg cgagaacaca aattgctatg gatattataa atgaaaatta cgattgtgca
     8341 aggtcttatt tgcatgggta taagatacca ggatttatga caggaatctc aggaatggga
     8401 tactctctat taagagattt gtacccagaa ttaccatgca ttttggctct ggagatttag
     8461 gagcgtaatt gctaagtaat atttaacaaa gggaggaact tgatgtttca aaaaaaagtg
     8521 cattatgttt cacagctagg aagcatggat tgtggcatag catgtctgac aatgattctt
     8581 aattattacg ggtgtaaaag tgatatcgtg gacatagggg cagagattca gattggcaga
     8641 gacggtatga ccttagctca aatgaaagaa ttagcagaaa agtatggatt taaatttgct
     8701 gcataccagt ataatcatga agaaaaaaac ttaatagagt atcttccagc cattttgtgt
     8761 aatgattccc actatgtggt agttgataaa actaagaaga aaggaaaata tattctgttt
     8821 gatccagcaa atggaaaaag agttgtcgat tttttagaat taaaaaacgg atacaaggat
     8881 attcttgtat ccgttattcc aagtagaaat attaagaaaa taaaaaaaac caaatttaaa
     8941 atagaggtaa aattctctca atttatgatt gcaattatgt tgatgcttat gtgtcaactt
     9001 attacattag ctgttccaat ggttgtgcaa aaagtaatag atagtttatc ttctgcccat
     9061 attacaattc atatatggaa aattacactt ttagttcttc tgattatgtg tgcccatttt
     9121 gtattgagct tactaagaca gaaaatttta ttgaatatta acatgaaact ttttaaaaca
     9181 atgatttcta atatgattca taaaattttc cgtttggatg taagtttttt tgaatggcat
     9241 tccgcaggtg acatagggaa ccgtttcaat agtataaatc agttgaacga cattcttacc
     9301 aatggattta taaacattat aatccaaggg attacatcct tggtatgttt agctgttatg
     9361 accagtatat ctccatattt gactgcattt gttctagttg tttctattat acagatcgcc
     9421 ataatgattt tattaaatgg taaaaatctc ataaagacga aagagtatat atactcacag
     9481 agtacaatac agggagaact gatagatact ctggagaata taatggaaat aaaatgtatg
     9541 gggatggata atgcagttaa atcaaattta caaaattctt atagtaagtt aatagaaaga
     9601 ttcaagggaa aaactcgaat tagtaatttg atgaatagtt tttcctcaac cttaaacttg
     9661 attttccctt taatgattta cgtgattgga agttatagtg tgaagcaagg agggttaacg
     9721 ataggacaac ttatagccta tgcaacctta gtgggatatt ttacagcacc ttttactacc
     9781 gttgtattgt tgttaccgag tatcaatagt attaaagaag tgcttttacg ttataaggaa
     9841 ctaatgattt ttagagaaaa ttatcatacg ggagttcttg tacctggaaa atttgaaaat
     9901 ttaaaaataa gttcggtttc atattgctac aatagtgggc aggcatacgc attgaataat
     9961 gtttctcttg atcttaggcg aggcgagaga attgctattg ttggtttatc gggtagtgga
    10021 aaatcaacct tgataaaagc catactgggt gccgtggata ttaatcaagg atgtattgag
    10081 ataaataatt atgatatcag atcaatgtcg aaggaacaga tttataaatg gttttcagta
    10141 gttactcaaa atcctatgtg cttaaatgca agtataagaa agaatattga tattataggt
    10201 gatgctccgg atgagaaaat atggaaggta ctagacattg tagcattaaa agaggaagtt
    10261 ttaagtatgc cgttgggatt ggatacactt gttggagaag gaggacaaaa tatttcaggt
    10321 ggtcaaaaac agcgtattgc catagcaaga gctctgctta gcgatacgga ggtagttatt
    10381 tttgatgaag ctaccagtaa tctggatcag cttacagaaa agaaaattta tgataaccta
    10441 aggtctacca ataaaacgca aattatcatt actcatagac tttcctctat tcgagatacg
    10501 gattatatct atgtattgaa caggggaagc atcattgaac agggaacaca tttggatttg
    10561 atgaagaaaa agggatggta ttttgagagt attcaatgac agataggaat taaattatga
    10621 tatgaaaagc cattgtatgg ggaggtatta cagatgaaga agaaagagat agttattggg
    10681 gtgagcgtac tgattagtgc atcacttccc atttcagttt atgctgcttc aaatgaaagt
    10741 atgagttcta gaggttttat aattgatgaa actaatgagt ttgaggatat cgttaagcaa
    10801 attttagatg ttaagtcaaa acatccggaa tggagtgaac agcagataag tgattttatg
    10861 gatcagattc atgctattaa gaaagatggc gtcatagaca tttggaacgc acttacttct
    10921 tctgagaaaa aattagtgat tcgatatccg tttgatgcac taaaagtcaa taaagcaaag
    10981 gaaattgcca ctaaacaaac cgaaagaaaa ttcggaaaaa atggtttggg tgacaggagt
    11041 gacgcattta gacacggaat atggaatgcc gaaatgacag ttttgatagg aagtgaaaaa
    11101 gcagagcttt ttgcgacagc acatgaagat aaagatacta ctggaaacga aagcgatgga
    11161 tatacaaaag atgagcacaa aaaaatggat ttacataaca atgaaatagg gaggaaatta
    11221 ggtgcagata acctatctgc accagaagag aaaatggcgg aaatcatata tgacgagata
    11281 atgagagaag attcgctgtt tgtatggctg catgaatgaa aaagttagaa cgtatgaact
    11341 gaaatgaaat atatctctaa gacagtcgca gatattttat tgatgtttag atatctgtga
    11401 ctgtttttga atagaaataa tagtcgttaa aaatgtctgc tctgactaaa tttgaaagaa
    11461 gaatcagaat gagaaccaag tactaatgta tagccatgaa ttagatgtga aatctgttaa
    11521 atgatggtca aatgagaatg agggggctgt agaaaaatat ttatcaacat attatttgtc
    11581 gatttagttt aagtaatgac aataacaata ataaaggggg acttgatttc tcatatcccc
    11641 cagtgtataa tctaattaag aaaggtaatc agatgcaaga tctgatgccc tcagtaaaat
    11701 ttaatttttt tctatgttaa gacatagcat ccatcaaact ttctcagggt ttatcgtgga
    11761 tgctatttct tatcatgtcg attatctatg taagtcagag ccgcaaaaac tactaaaagc
    11821 aatgtgagta cttccattgt gttcatgggc atcaccctcc tttaaaaact agagggctgg
    11881 tcgaaattgc atccgcatct ctttctcgat tagctatact cgctcagtat agcatggaat
    11941 atcttgtatc gcaataagaa atggatgtag tgagctcctt ttcatattgc ttttggtaat
    12001 cagatatttt gtttgataat ccttgtaatg atgccaacag caacattccg ttcttcatca
    12061 at
//
