LOCUS       NZ_JAQESL010000017     21657 bp    DNA     linear   CON 29-FEB-2024
DEFINITION  Coprococcus sp. AM97-35 AM97-35.Scaf17, whole genome shotgun
            sequence.
ACCESSION   NZ_JAQESL010000017
VERSION     NZ_JAQESL010000017.1
KEYWORDS    WGS; RefSeq.
SOURCE      Coprococcus sp. AM97-35
  ORGANISM  Coprococcus sp. AM97-35
            Bacteria; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae;
            Coprococcus.
REFERENCE   1  (bases 1 to 51109)
  AUTHORS   Lin,X., Hu,T., Chen,J., Liang,H., Zhou,J., Wu,Z., Ye,C., Jin,X.,
            Xu,X., Zhang,W., Jing,X., Yang,T., Wang,J., Yang,H., Kristiansen,K.,
            Xiao,L. and Zou,Y.
  TITLE     The genomic landscape of reference genomes of cultivated human gut
            bacteria
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 51109)
  AUTHORS   Zou,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-NOV-2022) BGI Reaserch, BGI-Shenzhen, Beishan
            Industrial Zone, Shenzhen 518083, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. v2.04
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: MGI
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/29/2024 10:49:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,361
            CDSs (total)                      :: 3,321
            Genes (coding)                    :: 3,266
            CDSs (with protein)               :: 3,266
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 6 of 55
            Pseudo Genes (incomplete)         :: 54 of 55
            Pseudo Genes (internal stop)      :: 2 of 55
            Pseudo Genes (multiple problems)  :: 5 of 55
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:11:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4043
            Orig. end                         :: 25700
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAQESL010000017.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21657
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..21657
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21657
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11657](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11657)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     misc_feature    complement(282..296)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 17.08"
                     /tool="antismash"
     misc_feature    579..592
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.07"
                     /tool="antismash"
     gene            complement(898..2397)
                     /gene="hemZ"
                     /locus_tag="PG840_RS11630"
     CDS             complement(898..2397)
                     /EC_number="1.3.98.3"
                     /GO_function="GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="hemZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008976439.1"
                     /locus_tag="PG840_RS11630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="coproporphyrinogen dehydrogenase HemZ"
                     /protein_id="WP_270613664.1"
                     /sec_met_domain="PF04055 (E-value: 4.6e-24, bitscore: 77.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRISCKNERFTYDMYHIVKSFLPDAEISQKVDPEQELLIEMTAE
                     EEPDLEEQACDKKVRWTFFHCREAEIADISEKREQKRYINKKLYQTLVKKTGEEHAWGN
                     MTGVRPTKMIMERLEEGSSEEEIIRYMHDTYVVSEKKAMLGIEIAKREKAQLDKLDYEN
                     GYSLYIGIPFCPTTCSYCSFTSYPVAKWQNRMDEYVDALLKELAFIAEVSKEKHLNAIY
                     MGGGTPTTLSAQQMDRVLSFLEEHFSFEHLKEYTIEAGRPDSITEDKLRVIRKHGVGRI
                     SINPQTMQQKTLDVIGRRHTVEDVVRIFHLARELGFDNINMDLIAGLPGEHPEEMEDTL
                     RQIKELAPDSLTVHALAMKHGSRLTRERAASTEKQNYKQMARELEEMIDMARKAAGEMG
                     LYPYYLYRQKNIAGNFENVGYAKVDKAGIYNILIMEEKQSIVAAGAGASTKVVLPYEIP
                     APGSKNGRMTNLIRIENVRDVGEYISRIDEMIERKGEWLWH"
     gene            complement(2410..3033)
                     /locus_tag="PG840_RS11635"
     CDS             complement(2410..3033)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605091.1"
                     /locus_tag="PG840_RS11635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_008369645.1"
                     /transl_table=11
                     /translation="MKIEKFVTGIISTNCYIVTNEETKETVIVDPANLSKAMIGYIEEE
                     ELVIKAILLTHAHFDHIMGIDKVIDRYGEMPVYVEESDLELLHTPSMNESTVYTNGYSY
                     PGGDVIHDGDVLHLIGEDFRVIHTPGHTQGGVCYYVEKEGVLFSGDTLFCCSVGRSDFA
                     TSSTSALIRSIKEKLFLLPDETKVFPGHMGATTIGNEKVNNPYV"
     gene            complement(3040..5364)
                     /locus_tag="PG840_RS11640"
     CDS             complement(3040..5364)
                     /EC_number="2.7.6.5"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008369648.1"
                     /locus_tag="PG840_RS11640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="WP_181988839.1"
                     /transl_table=11
                     /translation="MADDIGIQQEMLIEPTHKKLEIVDGHAVKDVEDYQNPELLYKSLI
                     ERVRKYHPSADVSMIEKAYHIARDAHKGQTRKSGEEYIIHPLWVGIILAQLEMDKETIV
                     AGILHDVVEDTVMTDEEIRQEFGDEVALLVDGVTKLGQLSYSADKLEVQAENLRKMFLA
                     MAKDIRVIIIKLADRLHNMRTLQYMRPEKQLEKAKETMDIYAPIAQRLGISKIKTELDD
                     LALKYSQPEVFNDLVKQINARKTEREEFVQQIVDEVSTHMKNANIDAEVNGRVKHFFSI
                     YKKMVNQDKTVDQIYDLFAVRIIVDSVKDCYAALGVIHEMYTPVPGRFKDYIAMPKANM
                     YQSLHTTLMSSIGQPFEIQIRTKEMHKTAEYGIAAHWKYKESEDGKKSVEAKEEEKLSW
                     LRQILEWQRDMSDNREFLNLLKGDLDLFAEDVYCFTPNGDVKNLPNGSTPVDFAYAIHT
                     AVGNKMVGARVNGKLVNIDYKIQNGDRIEILTSQNSKGPSRDWLSIVKSTQAKNKINQW
                     FKKEFKEENIVRGKEMLAAYCKAKGFVLSDLMKPKYMQIVQEKYGFKDWDSILAALGHG
                     GLKEGQIVNRLAEEYSKDHRKELTDESVLEKVAEAAKNKVHITRSKSGIVVKGIDDMAV
                     RFSRCCNPVPGDEIVGFITRGRGMSIHRTDCVNIIHLSETERARLIPAEWEKPEEGTDT
                     GSYLAEIKMYANDRQGLLMDMSKVFTEMNIDVKSMNVRTSKQGTATIEAGFIVRGREEL
                     GKVIGKLRQIVGVLDIERAVG"
     gene            complement(5384..5908)
                     /locus_tag="PG840_RS11645"
     CDS             complement(5384..5908)
                     /EC_number="2.4.2.7"
                     /GO_function="GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008369651.1"
                     /locus_tag="PG840_RS11645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="WP_022221132.1"
                     /transl_table=11
                     /translation="MKKLEEYVVSIPDYPEKGIIFRDVTSILEDPEGLQLSIRELQDKL
                     EGMDFNIVIGPESRGFIFGMPIAYNLQKAFVPIRKKGKLPCETASIKYDLEYGSAEIEI
                     HKRSIKPGDKVVIVDDLMATGGTAEAMIKLIEGLGGEVVEVLCLIELMGLKGREKLKGY
                     KVDSVIQYPGN"
     gene            complement(5980..7740)
                     /gene="recJ"
                     /locus_tag="PG840_RS11650"
     CDS             complement(5980..7740)
                     /GO_function="GO:0008297 - single-stranded DNA
                     exodeoxyribonuclease activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440042.1"
                     /locus_tag="PG840_RS11650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="WP_270613665.1"
                     /transl_table=11
                     /translation="MENWVLLRKGADFQHISEKFHISPRVASLIRNRDVIGDDAIEKYL
                     NGTIADLYDGMLMKDMDKAVAVLGEKIKENAKIRIIGDYDIDGIQSTYILLEGFRMLGA
                     DVDSDIPDRMKDGYGLNRNLIDRALEADVDTIITCDNGIAAAEEIAYAKSMGMTVVVTD
                     HHEVPYTEIGGERRYILPEADAVVDPKQEDCTYPFKGLCGAAVAYKLVEALMEAMGKDA
                     EDADYLMENVAIATIGDVMDLVDENRIFVKQGLDMLKRTENLGLKALMECTGVNVDKLS
                     PYHIGFVIGPCMNASGRLDTAKRALELLEAKKVAEADLLAGDLKALNDSRKDMTAQAVE
                     EAFIQVENSELKDADVLVVYLPECHESLTGIVAGRIREKYYRPVFVLTKGAEGLKGSGR
                     SIETWHMYEGLNRVKHLLSKFGGHKMAAGLSMPEENLEQFRKEINEKSGITPEDLNEKI
                     AIDMQLPFECVNEKFIGELAVLEPFGKGNARPVFAERQVQVESARILGKNKNVLKLQVK
                     DLHGTRMDAMYFGDVNTFVEYVREKFGDIACECLLHGHGHGIVMAFTYYPDINEYQGVR
                     TPQIVIQNYK"
     gene            complement(7820..9985)
                     /gene="secD"
                     /locus_tag="PG840_RS11655"
     CDS             complement(7820..9985)
                     /GO_component="GO:0031522 - cell envelope Sec protein
                     transport complex [Evidence IEA]"
                     /GO_function="GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA]"
                     /GO_process="GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /gene="secD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016293859.1"
                     /locus_tag="PG840_RS11655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="protein translocase subunit SecD"
                     /protein_id="WP_117558970.1"
                     /transl_table=11
                     /translation="MKKSKGIVSLVLIAALLGLLGFTCWQGFGSSHTGSARNINLGLDL
                     AGGVSITYQTKDKNPSAEDMKDTIYKLQKRVEQYSTEASVYQEGDDRINIEIPGVSDAN
                     KVLEELGKPGSLVFQDADGNTVLEGTDVKNAEAQTQENSTTKNKEYVVALQLTKEGTTK
                     FAEATAANVGKQISIIYDGQTISSPRVNQAIEGGEAVITGMSSYEEADNLAATIRIGGL
                     SLELEELRSNVVAAQLGEEAISTSLMAGAIGLAIIFVFMCFVYLIPGLAAGLALLIYTG
                     LILVLLNAFNITLTLPGIAGIILGIGMAVDANVIIFARVREEVTTGISVKTSLKNGFHK
                     ALSAIVDGNVTTLIAAAILWFKGSGSVKGFAQTLALGIVVSMFTALVITRIIIFSLYAI
                     GLRDVKFYAKKFKKERKVIDFLGKKAIFFAISIAVIAAGFVTMGVQSGKGEGALNYSLE
                     FKGGTATTVTFDKDYSIKEIDSKIVPVVEDVTGDHNVQAQKVKDSNQIIIKTQTLNLDE
                     REALNNALADKFGVDTSTITAENISSTVSSEMRQDAIIAVIISAICMLIYIWFRFKDVR
                     FASSAVLALLHDLLFVLTFYALARTSVGNTFIACMLTILGYSINATIVIFDRIREELRV
                     MKRNDDLKALVNRSITYTLTRSIYTTFTTFVMVAVLYIMGVSSIKEFAAPLMVGIAGGG
                     YSSVCITGALWYVMKTKIGGKKAAKKK"
     gene            complement(10001..11398)
                     /gene="scfB"
                     /locus_tag="PG840_RS11660"
     CDS             complement(10001..11398)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="scfB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008369657.1"
                     /locus_tag="PG840_RS11660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="WP_117558972.1"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1.2e-29,
                     bitscore: 94.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 5.7e-78, bitscore:
                     253.9, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 9.5e-18, bitscore: 56.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4.6e-15, bitscore: 47.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 6.3e-19, bitscore:
                     59.7, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHQYQNNGYNIVLDVNSGCVHVVDEPGYEVIACLNRMNENQTVQ
                     TLKEESTWNQLKDELEGKYSEEELRDILDDVTELTENGQLFVVDTYEPFIGEVIKRKTV
                     VKALCLHIAHDCNLACKYCFAEEGEYHGRRALMTYEVGKKALDFLIANSGTRRNLEVDF
                     FGGEPLMNWQVVKDLVAYGREQEKLHDKHFRFTVTTNGVLLNDDIQEFINKEMDNVVIS
                     LDGRKEVNDRMRPFRNGKGSYDLIVPKFQKLADSRNQERYYIRGTFTRNNLDFSEDVKH
                     FAELGFKQMSIEPVVGDESDPYAIREEDLPQIFDEYDKLARYIIEKDKKGEGFNFFHFM
                     IDLEGGPCLYKRLSGCGSGTEYLAVTPWGDFYPCHQFVGDEDFLMGNVNEGITRPEIAD
                     EFRCCNVYTKEKCKKCFARFYCSGGCMANAYKYADGLNDSYDLGCEMERKRVECAIMIK
                     AAMADEN"
     aSDomain        complement(11066..11398)
                     /aSDomain="Ranthipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a
                     ranthipeptide/SCIFF cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_PG840_RS11660_Ranthipeptide_rSAM_RRE.
                     1"
                     /evalue="7.60E-30"
                     /identifier="RREFam024.1"
                     /label="PG840_RS11660"
                     /locus_tag="PG840_RS11660"
                     /protein_end="111"
                     /protein_start="0"
                     /score="94.1"
                     /tool="antismash"
                     /translation="MIHQYQNNGYNIVLDVNSGCVHVVDEPGYEVIACLNRMNENQTVQ
                     TLKEESTWNQLKDELEGKYSEEELRDILDDVTELTENGQLFVVDTYEPFIGEVIKRKTV
                     VKALCLH"
     gene            complement(11514..11657)
                     /gene="scfA"
                     /locus_tag="PG840_RS11665"
     CDS             complement(11514..11657)
                     /codon_start=1
                     /gene="scfA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605085.1"
                     /locus_tag="PG840_RS11665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="WP_008369659.1"
                     /sec_met_domain="TIGR03973 (E-value: 1.6e-27, bitscore:
                     86.7, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 1.6e-27, bitscore: 86.8,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHIKTLNTQTLNNTVKKGGCGECQTSCQSACKTSCTVGNQTCEH
                     SK"
     gene            complement(11918..12289)
                     /locus_tag="PG840_RS11670"
     CDS             complement(11918..12289)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008369690.1"
                     /locus_tag="PG840_RS11670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TIGR04086 family membrane protein"
                     /protein_id="WP_270205701.1"
                     /transl_table=11
                     /translation="MEKKLFGNICFTRLVKALMLSYFLTMLMLLGLSFGLYKFDLSEKT
                     VRIGILAVYIISTFAGGFAMGKMGKTRKFLRGFMLGMFYFLLLLAISAGIYRSVQGGIQ
                     MMIAWILCGAGGMLGGMVS"
     gene            complement(12342..12890)
                     /gene="spoVT"
                     /locus_tag="PG840_RS11675"
     CDS             complement(12342..12890)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoVT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016293831.1"
                     /locus_tag="PG840_RS11675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage V sporulation protein T"
                     /protein_id="WP_022220492.1"
                     /transl_table=11
                     /translation="MKATGIVRRIDDLGRIVVPKEIRRTLRIREGDALEIFTDREGEII
                     LKKYSPLGEMGNFADQYAESLAQTLGYLVCITDTDQVIAAAGPGKKEFQEQLITRQLAE
                     VIARREQFLASSMDRKFTVIVSGQNAELKWQVVSPIICAGDAIGSVVILAKDGRKKPGE
                     LEQKMILCAAGFLGRQMEQ"
     gene            complement(12995..14017)
                     /locus_tag="PG840_RS11680"
     CDS             complement(12995..14017)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005541744.1"
                     /locus_tag="PG840_RS11680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_022220493.1"
                     /sec_met_domain="APH (E-value: 3.2e-22, bitscore: 71.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERIQGLKEYVQTEHYLEGIGIGKEEQKEIQITYQPLAQGEYNIN
                     YWFVHPLTGKKLVLRVNTGSQMHLENQIEYEYHALELLADSGRTPVPVFVDGSKKELPY
                     GVMVMEFLEGSALDYRKNLMEAAECLADIHSVPVKETDGLISPSNPLQAILDECNQMVQ
                     TYYESDLGEEKKKVQIRRLLELGQEKINEIRDYSGYRCCINTELNSGNFLMNGAGKDNY
                     LVDWEKPLYGDPVQDLGHFLAPTTTFWKTDVILTEEEMADFTRKYIQAVNGRFDVSGIE
                     ERLNIFIPITCLRGITWCAMAWVEYQEPGRLIRNEETFKKMEDYLNRDFLDMIEERYYK
                     "
     gene            complement(14019..14564)
                     /gene="rfbC"
                     /locus_tag="PG840_RS11685"
     CDS             complement(14019..14564)
                     /EC_number="5.1.3.13"
                     /GO_function="GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA]"
                     /GO_process="GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="rfbC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006568207.1"
                     /locus_tag="PG840_RS11685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="WP_044998736.1"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 4.6e-72,
                     bitscore: 232.7, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGQIKVEKNAGGIEGLCVIEPSVHGDQRGYFMETYNQKDMEEAGL
                     TMKFVQDNQSGSGKAVLRGLHFQKKYPQGKLVRVIRGTVFDVAVDIRKGSATYGKWYGI
                     ELSEENKKQFYIPEGFAHGFLVLSDQAEFCYKCTDFYHPDDEGGIAWNDPTINVAWPEL
                     DVPYRMSEKDKKWGRLGE"
     gene            complement(14572..15495)
                     /gene="rfbD"
                     /locus_tag="PG840_RS11690"
     CDS             complement(14572..15495)
                     /EC_number="1.1.1.133"
                     /GO_function="GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (61-169). E-value:
                     8.8e-13. Score: 39.9. Matches aSDomain:
                     nrpspksdomains_PG840_RS11690_NAD_binding_4.1"
                     /codon_start=1
                     /gene="rfbD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008369700.1"
                     /locus_tag="PG840_RS11690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="WP_022220495.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3e-97, bitscore:
                     316.6, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 6.4e-13,
                     bitscore: 39.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKFLVTGAAGQLGKDVVRELENRGYEVTGSGSKKRKTAGRYVKM
                     DITDRNEVEAVMKKLRPDIVIHCAAWTAVDAAEEPENYEKVWEVNGKGTANLASACQKI
                     HAKMVYISTDYVFGGQGSRPWEPDCEEFSPLNRYGETKLQGEQTVKAELKEYFIVRIAW
                     VFGKNGNNFVKTMLEQGKRRKELRVVCDQIGTPTYTADLAKFLANLSMTKRYGIYHVTN
                     EGEYVSWYDFAKEIFAQAVKLGEKEYADVKVIPVTTAEYGISKAARPFNSRLDRKRICE
                     EGFQPLPVWKNALERYLQEVLAERKG"
     aSDomain        complement(14989..15312)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PG840_RS11690_NAD_binding_4.1"
                     /evalue="8.80E-13"
                     /label="PG840_RS11690_NAD_binding_4.1"
                     /locus_tag="PG840_RS11690"
                     /protein_end="169"
                     /protein_start="61"
                     /score="39.9"
                     /tool="antismash"
                     /translation="PDIVIHCAAWTAVDAAEEPENYEKVWEVNGKGTANLASACQKIHA
                     KMVYISTDYVFGGQGSRPWEPDCEEFSPLNRYGETKLQGEQTVKAELKEYFIVRIAWVF
                     GKNG"
     gene            complement(15489..16487)
                     /gene="rfbB"
                     /locus_tag="PG840_RS11695"
     CDS             complement(15489..16487)
                     /EC_number="4.2.1.46"
                     /GO_function="GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (72-182). E-value: 5e-15.
                     Score: 47.2. Matches aSDomain:
                     nrpspksdomains_PG840_RS11695_NAD_binding_4.1"
                     /codon_start=1
                     /gene="rfbB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529743.1"
                     /locus_tag="PG840_RS11695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="WP_008369702.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.9e-21, bitscore:
                     67.2, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.7e-16,
                     bitscore: 51.6, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 3.6e-15, bitscore:
                     47.2, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIIVTGGAGFIGSNFIYYMMEKHSEDQIICLDALTYAGHMSTLE
                     VAMKNPAFRFVKASVTDRVTVYRLFEEEHPDIVVNFAAESHVDRSIENPEVFLDTNIKG
                     TAVLMDACRKYGIWRYHQVSTDEVYGDLPLERPDLFFTEETPIHTSSPYSASKAAADLL
                     VQSYHRTYGLPVTISRCSNNYGPYHLPEKLIPLMIVEALHDRPLPVYGDGKNVRDWLYV
                     KDHCRAIDLILRHGKEGEIYNVGGHNEMKNIDIVKLICRELGKPEELITYVEDRKGHDR
                     RYAIDPSKIHRELGWLPETSFAEGIKKTINWYLNHQEWWRPIVEKEMKIKC"
     aSDomain        complement(15942..16271)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_PG840_RS11695_NAD_binding_4.1"
                     /evalue="5.00E-15"
                     /label="PG840_RS11695_NAD_binding_4.1"
                     /locus_tag="PG840_RS11695"
                     /protein_end="182"
                     /protein_start="72"
                     /score="47.2"
                     /tool="antismash"
                     /translation="EHPDIVVNFAAESHVDRSIENPEVFLDTNIKGTAVLMDACRKYGI
                     WRYHQVSTDEVYGDLPLERPDLFFTEETPIHTSSPYSASKAAADLLVQSYHRTYGLPVT
                     ISRCSN"
     misc_feature    complement(16472..16486)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.75"
                     /tool="antismash"
     gene            complement(16504..17400)
                     /gene="rfbA"
                     /locus_tag="PG840_RS11700"
     CDS             complement(16504..17400)
                     /EC_number="2.7.7.24"
                     /GO_function="GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="rfbA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004851648.1"
                     /locus_tag="PG840_RS11700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="WP_022220496.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 4.5e-13, bitscore:
                     41.3, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGIILAGGSGTRLYPLTMVTSKQLLPVYDKPMIYYPLSVLMSAG
                     IREILIISTPQDTPRFEELFGDGHQFGIELTYAVQERPEGLAQAFIIGKEFIGNDAAAM
                     ILGDNLFAGHGLKKRLLEAVKAAERGDGATIFGYYVDDPERFGIVEFDEKGKAVSIEEK
                     PEHPKSNYCVTGLYFYDNRVSDYAGQLKPSRRGELEITDLNRIYLEQGRLRVELLGQGF
                     TWLDAGTHESLTDATNFVKTVETHQHRKIGCLEEIAYMNGWISRNALLEVCEKYRQNQY
                     GQYLHDVAEGKFRENLF"
     misc_feature    complement(17538..17553)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.06"
                     /tool="antismash"
     gene            17592..19916
                     /locus_tag="PG840_RS11705"
     CDS             17592..19916
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163: rhodanese domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012790.4"
                     /locus_tag="PG840_RS11705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_270613666.1"
                     /transl_table=11
                     /translation="MKRKLLPVFLSFALLANGSLTAFAADPVADAVTESDVQTTVSEDQ
                     ENQEEVTVPEGETSEEEASTEADDSKETSDVITDIAGRYTELGTDGNPIDGSKAIENAK
                     AGSGVIVDVRTPKNYNKGHIEGSISAPVFTSDGVVKRSDEPTAVAFTETVTGNSALEGK
                     EIYVLCNSGNAGAKAATVLLNAAGYSLDNIHTITYGATGLEVRYAFLGTNNAVTGAEAV
                     AAVDSSDVVIIDVRTTENYAKGHLKNSISQPVFYIDEKGEETVTPTNQDEYSKAFAKYV
                     TNNLSTFTGKKVYVLCNSGSRGARAATALLADNGVDKNTIYTITGGAKDETVKSAFVTV
                     DGYKFVSGNDAITAAKEGTAYVIDVRSTKAQAKTGTLKGSISQSLFDADNKLDTAEAEA
                     LEKAFKEEITSKITEDKPIYIICNSGARGAQKATKLLGELGYNTSTKEDGKVYTITNGA
                     KGLELLYAMSGTDGNAEDGKTAVAAVGKDDVAILDVRATGNYGAGHLKGSISTPVFNAD
                     GVAKTTDDQLSKDFTKYVTDNKATLEKKDLYLLCNSGASGARAATALLKAAGYDLAKVH
                     TITGGAKDADVNAAAIYVSDTHVINKMADTKNYLILDVRSTASYTKGHLKGSLSLPLFD
                     KDNKLPDDLAKAFTEYVTAHKADFEGKTIYVLCNSGARGAAKATQLLKEAGITNIKVFT
                     IENGAKSEVIQKHFVTDPVADPDTKKDNNGKDNNKNQNNGKTTTAATTKTGDTAPIAAL
                     AVAMLAALGAIIAFGKKKIVK"
     misc_feature    17634..17652
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 24.81"
                     /tool="antismash"
     gene            complement(20032..20940)
                     /locus_tag="PG840_RS11710"
     CDS             complement(20032..20940)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163: rhodanese domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008369706.1"
                     /locus_tag="PG840_RS11710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_270205703.1"
                     /transl_table=11
                     /translation="MKRTALFLAGILAISSLSGCGAKNSKSDSSEPFEGKYVVTADYVK
                     ENLDDIIVVDARGEDEAKKGTVKGAVATTWQYLATCEDGEAGDANWGCILDTKRLSERL
                     GELGLAKDKEIVLFSNAEKGWGEDGRIAWELIAAGYEDVKIVDGGIKALKAAGVETVKG
                     VAEPKPVSVEIDSIDETHVINTDELKEIYDDCKIVDTRTDKEYNGKTMYGEENGGHLPG
                     AIQIRYTDLFNSDSTLKSNEDLTKMFEDAGLSKEDHIITYCTGGIRSAYMQLVMEMCGF
                     ENSENYDESFYRWCVEGDLEK"
     misc_feature    21426..21439
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
ORIGIN
        1 catccattgt tacttcaaaa atggttcctg tatagtaaga ctgtccacgt accagcgtcg
       61 gatcaaattt cactttgaat tctgcctctt ttgcactttc tacgctggag atgatcgttt
      121 ccatgctgtc ggctgtcttt tcgtcaagga atcctgccag cttttccttg cagaaacgga
      181 ttccgtcaac atccgggctg atctcatcaa agagtccaag ataagtatct acattttctt
      241 ttgtataacc catctcaacc agttcttcgc ctacgccttc tttgccgatc ttatccatct
      301 tatcaaggat gataaatact tcatcgaaat cttcttcctt aaatccacta aatgcagcca
      361 tcgcctttaa gatattacgg tcattgatac ataccgtaaa attgtggaaa tccatctttc
      421 caagcatggt cgtagttgca aggatcagtt cgatctctgc aagattaccc ggctcaccta
      481 aaatatcgat atcgcactgc atgaactgac ggaaacgtcc tctctgcggg cggtctgctc
      541 tccatacatt gccaatctga agtgccttaa acggtgacgg cagttcattt gcatgatttg
      601 catagtatct tgcaagcgga actgtcaggt cataacgaag tcctccgtct accagatcga
      661 tctcttcttt tgcctcagca attttcagtt tttcccctct cttcagaatc ttaaaaatca
      721 gtttttcatt gtcgccaccc tgtttgctgc acaggttctc aatgtgttct acacacggtg
      781 tctctatgga agtaaatcca aatgtcttat aggtatcctt gatcatctgg atcacataat
      841 ctctgatttc catttctttc gggagcatgt ctttcatgcc ggtaaccggt tttttcttta
      901 atgccataac cattctcctt ttcgctctat catctcatcg atacgagaaa tatattctcc
      961 cacatctctg acattttcta ttcttatcag attcgtcatc cgcccgtttt tacttccggg
     1021 tgccggaatc tcatacggaa gcaccacctt agtcgatgcg cctgcaccgg cagcaacgat
     1081 ggactgcttt tcctccataa tcagtatatt gtaaattccc gctttgtcaa cctttgcgta
     1141 acctacattt tcaaaatttc ctgcaatatt cttctgtctg tagagataat acggataaag
     1201 tcccatttca ccggccgcct tacgtgccat atcgatcatc tcttccagct ctcttgccat
     1261 ctgtttataa ttttgttttt ctgtgcttgc agcccgttcg cgtgtcagtc tcgaaccatg
     1321 tttcattgca agtgcatgga ccgtcaaact atccggtgca agctctttga tctgacgaag
     1381 agtatcttcc atctcctccg gatgttctcc cggaagacct gcgatcagat ccatattgat
     1441 attgtcgaat cccagttctc ttgccagatg gaaaatgcgg actacatctt ccactgtgtg
     1501 acgtcttccg atcacatcca gtgtcttctg ctgcatggtc tgtggattga tggaaattct
     1561 gccaactcca tgctttcgga tcactcgcag cttgtcctca gtaatgctgt ccggtcttcc
     1621 ggcttcgatc gtatattctt tcagatgttc aaaggaaaaa tgttcttcca ggaaactcaa
     1681 aacccggtcc atctgctgtg cactcagggt tgtcggtgta ccgcctccca tataaatcgc
     1741 attaagatgc ttttcttttg aaacctctgc aataaatgca agctctttta aaagtgcatc
     1801 tacatattca tccatccgat tctgccattt tgcaaccgga taagaagtaa aggagcagta
     1861 actgcaggtt gtcgggcaga acggaattcc gatataaagg ctgtatccat tttcataatc
     1921 cagcttgtca agctgggctt tttcccgctt tgcaatctcg ataccaagca ttgctttttt
     1981 ctcgcttacc acataggtat catgcatata ccggatgatt tcttcctcag aagaaccttc
     2041 ttccagtctt tccatgatca tctttgtggg gcggacacct gtcatattcc cccatgcatg
     2101 ttcttctccg gtctttttga ccagggtctg atataatttt ttattgatat aacgcttttg
     2161 ttctcttttt tcactgatgt ctgcgatttc agcctccctg caatgaaaaa aggtccaccg
     2221 gaccttttta tcacatgcct gctcttccag atctggttcc tcttctgcgg tcatctcgat
     2281 cagaagttcc tgttctggat ctaccttctg gctgatttca gcatcaggaa gaaatgactt
     2341 tacgatatga tacatgtcgt aggtgaaacg ttcattctta cagctgatcc gaatcatttc
     2401 tctgctcctc tatacatacg ggttgttcac tttttcgttg ccaatcgttg ttgcgcccat
     2461 atgtcccggg aatacctttg tttcatccgg aagcaggaac agtttttcct tgatcgaacg
     2521 aatcagtgca gaagtgctgc tggttgcaaa atcacttctt ccgactgaac aacagaacaa
     2581 tgtatctcca ctgaaaagta ctccctcttt ttctacatag tagcatacgc cgccctgggt
     2641 atgtcccggt gtatggatca cccggaaatc ttctccgatc agatgaagca catctccatc
     2701 atggatcacg tctccacccg ggtagctgta gccatttgta tataccgttg actcattcat
     2761 agacggtgtg tgaagaagct ccagatcaga ttcttctacg taaaccggca tttctccata
     2821 ccggtcgatc actttatcga ttcccatgat atgatcaaaa tgcgcatgag tcagaagaat
     2881 tgccttaatt acaagctctt cctcttcgat ataaccgatc atcgcttttg acaagtttgc
     2941 cggatcaacg atcacggtct cttttgtttc ttcattggta acaatgtaac aattggtact
     3001 gataattcct gttacaaatt tttcgatttt catttctttt taccccactg ctcgttctat
     3061 atccagcaca ccgacgatct gccggagctt tccgatcact tttccaagct cctctcttcc
     3121 ccggacaata aatccggctt cgattgttgc cgttccctgt ttgctggttc ttacattcat
     3181 agacttcaca tcaatattca tctccgtgaa caccttggac atatccatca aaagtccctg
     3241 cctatcattt gcatacatct tgatctcagc cagatagctt ccggtgtctg taccttcctc
     3301 cggtttttcc cattctgccg ggatcagacg cgctctttcc gtttctgaca gatgaatgat
     3361 attgacacag tccgtccgat ggatcgacat tccacgtcca cgggtgataa aaccaacgat
     3421 ctcatctccc ggcaccggat tgcagcatct ggaaaagcgc actgccatat cgtcgattcc
     3481 cttgaccacg ataccactct tggatcgggt gatatgcacc ttgttctttg ccgcttccgc
     3541 aaccttttcc agaacacttt cgtcagtcag ttcttttcgg tgatccttac tgtattcttc
     3601 cgcaagacgg ttgacgatct gaccttcctt caatccgcca tgtccaagtg ctgcaaggat
     3661 cgaatcccag tccttaaagc cgtacttttc ctgcacgatc tgcatatatt tcggtttcat
     3721 cagatccgag agtacaaatc cttttgcctt acagtatgcg gcgagcattt ccttaccacg
     3781 tacaatattt tcttctttga attctttctt aaaccactgg ttgatcttgt tcttcgcctg
     3841 ggtactcttg acgatactca gccagtcacg gctcggtcct ttggagttct gcgaagtcag
     3901 gatctcgatt cggtccccgt tctggatctt ataatcgata ttgaccagct tgccattgac
     3961 tctggcacct accatcttgt tgccgaccgc agtatggatc gcataggcaa agtcaaccgg
     4021 cgtagaaccg ttcggcaggt tcttgacatc tccgttcggt gtaaagcagt atacatcctc
     4081 tgcaaataga tccaggtctc ctttcagaag attcagaaat tcccggttgt ctgacatgtc
     4141 tcgctgccat tccaggatct gacgaagcca gctcagtttc tcttcttcct tcgcttcaac
     4201 gctcttcttt ccatcttcag actctttata tttccagtgt gccgcaatac cgtattcagc
     4261 agttttatgc atctcttttg tacggatctg gatctcaaac ggctgaccga tcgaactcat
     4321 cagagtcgta tgcagagact ggtacatatt tgccttcggc attgcgatat aatctttaaa
     4381 acgtcccggt accggtgtat acatctcatg gataactcca agcgccgcat aacagtcttt
     4441 tacagaatct acgataatac ggactgcaaa cagatcatag atctgatcca ccgtcttatc
     4501 ctggttcacc atcttcttat aaatgctgaa gaaatgcttc acacgtccgt tcacttctgc
     4561 atcaatgttc gcattcttca tatgcgtgga aacctcatcc acaatctgct ggacaaattc
     4621 ttccctttcc gtttttcttg cattgatctg ctttactaga tcgttaaaaa cctccggctg
     4681 ggaatatttg agtgccagat catcaagctc tgtcttgatc ttggaaatac caagccgttg
     4741 tgcgatcgga gcatagatat ccatggtttc ttttgctttt tccaactgct tctccggtcg
     4801 catatactgc agggtacgca tattgtgcag acggtcggca agcttgatga tgataacacg
     4861 gatatctttt gccatcgcaa ggaacatctt acgaagattc tcagcctgga cctccaactt
     4921 atccgctgaa taggaaagct gtcccagctt tgtgacaccg tctaccagaa gcgccacctc
     4981 atctccgaat tcctgacgga tttcttcgtc cgtcatcacc gtgtcttcta ccacatcatg
     5041 aaggatgccg gcaacgatcg tctctttgtc catctccagt tgtgccagaa tgattcctac
     5101 ccacagagga tggataatat actcttctcc ggatttccgt gtctgccctt tatgcgcatc
     5161 tcttgcaata tgatatgctt tttcgatcat agagacgtcc gccgaaggat ggtactttct
     5221 gactcgctcg atcagacttt tatagagcag ttccggattc tgataatctt ccacatcctt
     5281 taccgcatga ccatctacga tctccagttt tttatgtgtt ggttcgatca gcatctcctg
     5341 ctggattccg atatcgtctg ccatagcctt cccttctttc tcattagttt cccggatact
     5401 ggattacgga atctactttg tatcctttca gtttttcccg tccttttaat cccatcagtt
     5461 cgatcaggca gagaacttct acaacctcac cgccaagtcc ttcgatcagt ttgatcattg
     5521 cttctgccgt accgcctgtt gccatcaggt catctacaat cacaaccttg tctcccggtt
     5581 tgatcgaacg cttgtggatc tcgatctctg cacttccata ttccagatca tacttgatcg
     5641 atgctgtctc gcaaggaagc tttccttttt tacggatcgg cacaaatgct ttttgcagat
     5701 tatatgcaat cggcattcca aaaataaatc ctctggactc cggtccgatc acgatgttga
     5761 aatccatgcc ttcaagctta tcctgcagtt cccgaatgga aagctgaagc ccttccggat
     5821 cttcaagaat gctggttaca tctctgaaaa taattccttt ttccggataa tccggaatgc
     5881 tgacaacata ttcttcaagt tttttcatct ttcttctcca ccttacctac aaatatatgc
     5941 aatatttatt agtatagcat aaaattgctg tttttcaaat tatttataat tttggatcac
     6001 aatctgtggc gtacggactc cctgatactc attgatatca ggataatagg taaatgccat
     6061 aacaattcca tgcccatgtc cgtgcagtag acactcacag gcaatatctc caaatttttc
     6121 acgcacatat tccacaaagg tattcacatc tccaaaatac atggcatcca tccttgtacc
     6181 gtgaagatcc ttcacctgca acttcagcac atttttattc ttgccaagga ttctcgcact
     6241 ttccacctgt acctgtcttt ctgcaaagac cggacgtgca tttcctttgc caaatggttc
     6301 cagaaccgca agctctccga taaatttttc attgacacat tcaaacggga gctgcatatc
     6361 tatggcaatc ttttcattca gatcctctgg tgtgatcccg gatttttcgt taatctcctt
     6421 acggaactgt tccagattct cctccggcat ggagagacct gccgccatct tatgcccgcc
     6481 aaattttgac aacagatgct ttacccggtt cagtccttca tacatgtgcc aggtctcgat
     6541 cgatcttcct gagcccttta aaccttccgc gcccttcgtc agcacaaaga ccggacggta
     6601 atatttttcc cggatccttc ctgccacaat cccggtaagg ctttcatgac attccggcag
     6661 gtagaccacc agcacgtctg catccttaag ttcactgttc tccacctgga taaacgcctc
     6721 ttctaccgcc tgcgccgtca tatccttccg gctgtcattg agtgctttca gatcacctgc
     6781 cagcagatcc gcctccgcca ctttctttgc ctccagaagc tccagggcac gctttgctgt
     6841 atccagtctt ccactggcat tcatacacgg gccgatcaca aatccaatgt gatacggaga
     6901 cagcttatct acattcacac cagtacattc catcagcgcc ttcagtccca gattctccgt
     6961 ccgtttcagc atatccagtc cctgtttaac aaaaatacgg ttttcgtcca ccagatccat
     7021 aacatcaccg atcgttgcga ttgccacatt ttccatcaga taatctgcat cttccgcatc
     7081 ttttcccatg gcttccatca gagcctccac cagcttgtaa gcaaccgcag ccccgcacag
     7141 ccctttgaac ggataagtac agtcctcctg cttcggatcc acaaccgcat ctgcctccgg
     7201 caaaatatat cttcgttccc cgccaatttc cgtatacggg acctcatgat gatccgtcac
     7261 cacaaccgtc attcccatac tttttgcata ggcgatctcc tctgccgccg caatcccgtt
     7321 atcacaggta atgatcgtat ccacgtcggc ctccagcgcc cggtcgatca ggttccggtt
     7381 tagaccatac ccgtccttca tacgatccgg aatgtcactg tccacatcag ctccgagcat
     7441 ccggaatccc tccagaagaa tataggtcga ctggattcca tcaatatcat agtctccaat
     7501 gatcctgatt tttgcatttt cttttatctt ttctccaaga accgctactg ccttgtccat
     7561 atccttcatc agcattccat cgtacagatc ggcgatcgta ccgtttaaat atttctcgat
     7621 cgcatcatcc ccgatcacat cccggtttct tatcagggaa gccactcgcg gactgatatg
     7681 gaatttctca ctgatatgct gaaaatccgc tccttttctc agaagtaccc agttctccat
     7741 tttctctttt cctttctttg gtagtcagat aatacaaaga tgccggagga ttctcctccg
     7801 acacctcatt ttctgtcagt tatttctttt tcgctgcttt tttgccgccg atttttgttt
     7861 tcattacata ccataatgca ccggtgatac atacagatga atatccgcca cctgcaatac
     7921 caaccataag aggtgctgca aattctttaa tagagcttac acccatgata taaagaaccg
     7981 ctaccatgac aaatgtagta aatgttgtgt aaatacttct tgtcagtgta taagtgatac
     8041 ttctgtttac aagcgctttc agatcatcgt ttctcttcat gacccgaagc tcttcacgga
     8101 tacggtcgaa aataacgatc gtcgcattga tagaatatcc aaggattgtc agcatacatg
     8161 cgataaatgt attaccgaca gatgttcttg caagtgcata gaatgtaagc acaaataaca
     8221 aatcgtgtaa aagagcaaga accgcacttg atgcgaaacg tacatctttg aaccggaacc
     8281 agatatagat cagcatacag atcgctgaaa tgataactgc aatgatcgca tcctgtctca
     8341 tctcggagct taccgtagaa ctgatatttt ctgctgtaat tgtcgatgtg tctacaccaa
     8401 atttatcagc aagcgcattg ttaagtgctt ctctttcgtc aagattcagc gtctgtgtct
     8461 tgatgatgat ctgattgctg tcttttacct tctgtgcctg tacattgtga tctccggtca
     8521 catcttctac aaccggaacg atctttgaat caatctcttt gatcgagtaa tctttatcaa
     8581 atgttacggt tgtagccgta ccgcccttga attccaggct gtagttcagc gcaccttcac
     8641 cttttcccga ctggactccc attgttacaa aacctgctgc gatcacagca attgatattg
     8701 caaagaaaat ggctttcttt ccgaggaagt cgataacttt tctttctttt ttgaatttct
     8761 tcgcataaaa tttcacatca cgaagaccaa tcgcatacag agagaaaatg atgatcctgg
     8821 taataacaag tgccgtaaac attgacacaa caataccaag tgccaatgtc tgtgcaaatc
     8881 cttttacaga acctgaaccc ttgaaccaga gaatagctgc agcgatcaga gttgttacgt
     8941 taccgtcaac gatcgcagac agtgctttgt ggaaaccatt cttcagggaa gtcttaacac
     9001 tgatacctgt tgtcacttct tcacgcacac gggcgaaaat gataacgttg gcatcgactg
     9061 ccataccgat tccaaggatg atacctgcaa ttcccggaag ggtaagcgtg atattaaatg
     9121 catttaaaag caccaggatc agtcctgtgt agatcagaag tgctagacct gctgcaagtc
     9181 ccggaatcag atatacgaag cacataaata cgaagatgat ggcaagtccg atggcaccag
     9241 ccattaagct tgtgctgatt gcttcttctc cgagctgtgc agctactaca ttagagcgaa
     9301 gttcttccag ttccagagaa agtccaccga ttcggatggt agctgcaaga ttgtctgctt
     9361 cttcatagct tgacatccct gtgataacgg cttctccgcc ttcgatcgcc tgattaactc
     9421 ttggtgaact gattgtctgt ccatcataaa taatggaaat ctgttttcct acatttgctg
     9481 ctgttgcttc tgcaaatttg gttgttcctt ctttggtaag ctgcagagct acgacatatt
     9541 ctttgttctt agtcgtagag ttctcctgtg tctgagcctc tgcattttta acatctgttc
     9601 cttcaagaac ggtattgcca tctgcatcct gaaataccag tgatcctggt ttgccaagtt
     9661 cttccagaac tttattggca tcggatacac ctgggatctc gatgttgatc cggtcatccc
     9721 cttcctgata tacacttgct tctgtactgt actgctctac acgcttctgc agcttgtaga
     9781 tcgtatcctt catatcttct gctgaaggat tcttgtcttt tgtctgatag gtaatgctga
     9841 caccaccggc aaggtcaaga ccaagattga tatttcttgc ggaacctgtg tgggaggaac
     9901 caaatccctg ccagcaggta aatccaagaa gtcctaaaag tgcagcaatc agaacaaggc
     9961 ttactattcc tttactcttc ttcatgtcca agtccctttc ttagttttcg tctgccattg
    10021 cagcctttat cataatcgcg cattccacgc gcttacgttc catctcacat cccagatcat
    10081 aagaatcatt taatccgtct gcatacttgt atgcgtttgc catacatcca ccactgcagt
    10141 agaatcttgc aaaacatttc ttacattttt cttttgtata tacgttgcag caacggaact
    10201 catctgcgat ctccggtctt gtaatccctt cgtttacatt tcccatcagg aaatcttcat
    10261 cacctacaaa ctggtgacac ggatagaaat ctccccatgg cgtaacagca aggtattcgg
    10321 ttcccgaacc acatccggac agacgtttgt acagacacgg tcctccttcc aggtcgatca
    10381 taaagtggaa gaaattgaat ccttctccct ttttatcttt ctcgatgata tatcttgcaa
    10441 gcttgtcata ctcatcaaag atctgtggaa gatcttcttc gcggattgca tacggatcag
    10501 attcatcccc gacaaccggt tcgatcgaca tctgcttgaa gccaagctct gcaaagtgct
    10561 tcacatcctc tgaaaaatcc agattgtttc tggtaaatgt tccgcggata tagtagcgtt
    10621 cctgattacg tgaatctgca agcttctgga acttcggaac gatcaaatca tagcttcctt
    10681 ttccgtttct gaaaggacgc attctgtcat taacttcctt acgtccgtca agactgatga
    10741 ctacattgtc catttcttta ttgataaact cctggatgtc atcattcaga agtacaccat
    10801 tcgtagttac agtaaaacgg aaatgcttgt catgaagctt ctcctgttct cttccgtatg
    10861 ccaccaggtc ttttacaacc tgccagttca tcagcggctc cccgccaaag aaatcaactt
    10921 ccagattcct tcttgttccg gaattggcga tcaggaaatc cagggctttc ttaccaactt
    10981 cataagtcat aagcgctctt cttccgtgat actctccttc ttctgcaaaa cagtatttgc
    11041 aggcaagatt gcagtcgtgt gcgatatgca aacaaagtgc tttcacaact gtcttacgct
    11101 tgataacctc cccgataaaa ggttcatatg tatcaacaac aaaaagctgt ccattctcag
    11161 tcagctctgt cacgtcatcc aatatatctc tgagttcttc ttcggaatat ttcccttcca
    11221 gctcatcttt cagctggttc catgtacttt cttctttcag cgtctgcact gtctgattct
    11281 cgttcatacg gttcagacat gcaataactt cgtaccccgg ctcgtccact acatgaacgc
    11341 atccgctgtt gacatcaagt acaatattat atccattgtt ctggtactga tgaatcacaa
    11401 ccggtacccc tttctatcct tatttttcaa atttttcctc atacgtcaaa tgacagcggc
    11461 tttaaagccg ctgcctgctt gtcatactta ttcactacac ttacaaatat ctcttatttg
    11521 ctgtgttcgc aagtctgatt tcctactgta caagaagtct tgcatgctga ctgacaggat
    11581 gtctggcatt ctccgcatcc gcccttcttt actgtattgt tcagagtctg tgtattcaat
    11641 gttttaatgt gtttcattgt aatatcctcc ttctttgctc attatgtgat acagtataac
    11701 acattttcca acttaccgtc aacgcaaaaa tccaatctga aacaaatgtg tgaaacaaat
    11761 gggcaaaatc cagtttttct ttacaatcct tacattcatg caagtgcccg gagtcattac
    11821 tgctccttcc gaagcaactg cttcctccgg attaaaaaat aaaagtatcg cccatatccc
    11881 ttgataccgt caacgcaaaa attacatctc cgccccttca ggacaccata ccaccgagca
    11941 ttccgcctgc cccacagagg atccaggcga tcatcatctg tattccaccc tgcacgctcc
    12001 ggtagatccc tgctgaaatt gcaagcagga gcagaaaata gaacattcca agcataaatc
    12061 ccctcaggaa tttccttgtc ttccccattt ttcccatggc aaatccaccg gcaaatgtgg
    12121 aaattatgta aaccgcaagg atcccgatcc ggactgtttt ctcgcttaag tcaaacttat
    12181 acagtccaaa ggacagcccg agcagcatca gcatcgtaag aaagtaagaa agcatcagtg
    12241 ctttcacaag tcttgtaaaa cagatatttc caaacagctt tttttccata agaacccctc
    12301 ctgtcctttt atactatgag agattcttat gaaatattcc tttactgttc catctgtcgt
    12361 cccagaaatc ctgctgcgca gagtatcatc ttctgttcca actcaccggg ttttttcctg
    12421 ccgtcctttg ccaggatcac gacagaaccg atcgcatctc cggcgcagat gatcggactt
    12481 accacctgcc atttcagttc tgcattctgt cccgacacga tgaccgtgaa cttccgatcc
    12541 atagaggatg ccagaaactg ctcccttctt gcgatcactt ccgcaagctg tcttgtgatc
    12601 agctgttcct gaaattcttt cttccccggt cctgctgctg caatcacctg atctgtatct
    12661 gtgatacaca ccagatatcc aagcgtctgc gccagacttt ccgcatattg gtctgcaaaa
    12721 tttcccattt ccccaagcgg tgagtatttt ttgagaatga tttctccttc ccggtcggtg
    12781 aaaatttcaa gtgcatcacc ctcacggata cgtagcgtgc gcctgatttc cttcggaacg
    12841 acaattctgc caagatcatc gatccggcgg acaattcctg tagctttcat attgattcta
    12901 ttcctcctgt gttccacata ttttccataa tttattcgat atgggtagta tgtggaaaaa
    12961 cgtaggattt tattactccg tatccctgaa atctttattt ataatatctt tcttcgatca
    13021 tatccagaaa atcccggttt aaatagtctt ccatcttttt aaatgtttct tcgttgcgga
    13081 tcagtcttcc cggctcctga tattctaccc acgccattgc acaccatgta attcccctga
    13141 gacacgtgat cggaataaaa atgttcagac gttcttcgat tccactcaca tcaaatctgc
    13201 catttaccgc ctggatatat tttcttgtaa aatcagccat ctcttcttct gtcagaatca
    13261 catctgtttt ccagaaagtt gtcgttggtg caaggaaatg ccccagatcc tgaaccggat
    13321 caccataaag cggcttttcc cagtcaacca gataattgtc ttttcctgcg ccattcatca
    13381 ggaaatttcc tgaattcagc tctgtgttaa tacagcatct gtatccacta taatcccgga
    13441 tctcattgat cttctcctgt cccagctcca gaagacgccg gatctgtact tttttctttt
    13501 cttctcccag atcagactcg tagtatgtct gcaccatctg attacattca tccagaatcg
    13561 cctgcagtgg attcgatggc gatatcagtc catccgtttc ttttaccgga acactgtgga
    13621 tatccgcaag acattctgcc gcttccatca gattcttccg ataatccagt gcactccctt
    13681 ccagaaactc cataaccatc acaccatacg gcagttcctt cttacttcca tctacaaaaa
    13741 ccggcactgg cgtccgtcct gaatctgcca gaagctccaa tgcatgatat tcgtattcaa
    13801 tctgattttc cagatgcatc tggcttcctg tattgacacg aagcaccagt ttctttccgg
    13861 tcagtgggtg tacgaaccag tagttgatat tatattcgcc ctgtgccagt ggctgatagg
    13921 taatctgaat ttccttctgc tcttctttcc cgatcccgat tccttccaga taatgttctg
    13981 tctgtacata ttcttttaat ccctgaattc tttccatctt attctcccag ccttccccac
    14041 tttttatctt tttcactcat tctgtatggc acatcaagct ctggccatgc aacgttgatc
    14101 gtcggatcgt tccaggcaat cccgccctca tcatccggat gataaaaatc cgtacatttg
    14161 tagcagaatt ctgcctggtc gctcagcacc agaaatccat gcgcaaatcc ttccggaatg
    14221 taaaactgct ttttattctc ttccgacagt tcaattccat accattttcc ataggtggca
    14281 cttcctttcc ggatatccac cgccacatca aatacggttc cccggatcac ccggactagc
    14341 tttccctgcg gatatttctt ctgaaaatga agtcctctca gcactgcttt tccagaaccg
    14401 gactgattat cctgtacaaa cttcatcgta agtccggctt cctccatatc cttctgatta
    14461 taagtttcca taaaatatcc acgctgatca ccatgcaccg acggttcgat cacgcagagt
    14521 ccttcgattc cacctgcatt tttttctacc tttatctgtc ccattttcct tttatccttt
    14581 tctctctgca agaacttcct gcaaatatct ctccagcgca ttcttccaga ccggcagtgg
    14641 ctgaaatcct tcttcacaga tcctttttct gtcaagtctg ctgttaaacg gtcttgctgc
    14701 ttttgaaatt ccatattctg ctgtcgtaac cggaatcact tttacatctg catattcttt
    14761 ttcaccaagc ttcacagcct gtgcgaagat ttcttttgca aaatcatacc agctgacata
    14821 ttctccttca ttagtcacat gatagattcc atatcgcttt gtcatcgaca gatttgcaag
    14881 aaattttgca agatctgctg tgtaagtcgg cgttccaatc tgatcacata ccactcgaag
    14941 ttctttccgt cttttcccct gctccagcat ggtcttcacg aaattattcc cgtttttccc
    15001 gaatacccaa gcgattcgca caataaaata ctctttcagt tctgctttca ctgtctgttc
    15061 accctgtaat ttcgtttcac cgtatcggtt cagcggcgaa aactcctcac aatccggttc
    15121 ccacggtctg ctcccctgtc caccaaacac atagtctgta ctgatataaa ccattttagc
    15181 atgaattttc tggcaggcgg atgcaagatt tgctgtgccc tttccattaa cttcccatac
    15241 tttttcatag ttttccggct cttctgccgc atccaccgcc gtccacgccg cacagtggat
    15301 cacaatatcc ggtctgagct ttttcattac tgcctcgact tcgtttctgt ctgtgatatc
    15361 catcttcaca taacgacctg ctgtttttct ctttttgctg ccgcttcccg tcacttcata
    15421 tccccggttt tccagttcac gtacaacatc ctttccaagc tgcccggcag cacccgtcac
    15481 caaaaacttt agcattttat tttcatttcc ttttctacga tcggtctcca ccactcctga
    15541 tgattcagat accagttgat tgttttctta attccttctg caaaagaagt ttccggaagc
    15601 cagccaagct ctctgtggat ctttgacgga tcgattgcat atcttctgtc atgccctttc
    15661 cgatcctcca cataagtaat cagctcttcc ggctttccaa gctccctgca gatcagcttc
    15721 acaatatcaa tattcttcat ctcgttatgc ccgccgacat tgtaaatttc cccttctttt
    15781 ccgtgacgca ggatcaaatc gatcgcccgg cagtgatcct ttacataaag ccagtcacgg
    15841 acatttttcc catcaccata gaccggaagc ggccggtcat gaagcgcttc gacgatcatc
    15901 agcggaatca gcttttccgg cagatgatat ggtccatagt tgttggaaca acggctaatt
    15961 gtaaccggaa gtccatacgt tctgtgatag gactgtacca gaagatctgc cgctgccttg
    16021 gatgcactgt acggactgct cgtatggatc ggcgtctctt ctgtaaaaaa cagatccggc
    16081 cgttcaagcg gaagatcccc atacacctca tccgtagaaa cctgatgata acgccagatt
    16141 ccatatttcc ggcacgcatc catcaacact gccgttccct ttatattggt atccagaaag
    16201 acttccggat tttcaatcga ccggtccaca tgactttccg ctgcaaagtt aactactata
    16261 tccgggtgtt cttcctcaaa cagccggtat acagtcaccc gatccgtcac agatgctttc
    16321 acaaaacgga acgctggatt tttcattgct acttccaggg ttgacatatg ccctgcataa
    16381 gtcagtgcat ccagacagat gatttgatcc tccgaatgct tttccatcat ataataaata
    16441 aagttgctgc caataaatcc ggcgccgccg gtaacaatga ttttcataaa ctctctcccc
    16501 tgtctaaaat agattctctc tgaactttcc ttctgctacg tcatgcaaat attgtccata
    16561 ctgattctgt ctgtattttt cacagacttc cagcagtgcg tttctggaaa tccagccatt
    16621 catataggca atttcttcca gacatccaat tttccggtgc tgatgagtct ctaccgtctt
    16681 cacaaaattg gtcgcatctg tcagactctc atgggtgccc gcatccagcc aggtaaagcc
    16741 ctgacccaga agctctaccc gaagtcttcc ctgttccaga tagatccggt taagatccgt
    16801 gatctccagc tccccgcgtc tgcttggctt taactgtcct gcataatcgc tcacccggtt
    16861 atcataaaaa tacagacctg tcacacagta attacttttc ggatgttcgg gtttttcctc
    16921 aatggaaacc gccttgccct tttcatcaaa ttccacgata ccaaaccgtt ccggatcatc
    16981 cacataatat ccaaatatgg ttgcaccgtc tcctctctcc gctgctttta ccgcttctaa
    17041 aagacgtttc ttaagcccat gcccggcaaa caaattatcc cccaggatca ttgccgccgc
    17101 atcattgcca ataaattctt ttcctattat gaacgcctgc gcaagacctt ccggtctttc
    17161 ctgcaccgca taggttaatt cgatgccgaa ctgatgcccg tccccgaaaa gttcttcaaa
    17221 tctcggtgta tcctgtggtg tactgatgat caggatttcc cgaattcctg cactcataag
    17281 aactgacaac ggatagtaga tcatcggctt gtcatacaca ggtaaaagct gcttggatgt
    17341 caccatcgta agtggataga gccgggttcc tgatccgcct gccaaaataa ttcctttcat
    17401 tttcatatcc ccgtttttca tttttatctt tttattctac cacgaaacag cagttagttt
    17461 aataaaatct ctcaattata cctatagatt ttatctattc cgtttttata tatagattaa
    17521 aacaattatg aaatttttgt gaaaactgtt acaatgtaat cgtaacctaa ttttgagagt
    17581 aaggaggaaa aatgaaaaga aaattattac cagtatttct gtctttcgca ttacttgcga
    17641 acggctctct gacagctttt gccgctgatc cggttgctga tgccgttaca gaaagtgatg
    17701 tgcagactac tgtttcagaa gatcaggaaa accaggaaga agtaacagtt cctgaagggg
    17761 aaacttctga agaagaagct tctactgaag ctgatgattc taaagaaact tcggatgtta
    17821 ttactgatat cgctggtcgc tacacagaac ttggcacaga tggtaatcct atagatggat
    17881 caaaagccat cgaaaatgca aaagccggct ctggtgttat cgtagatgta cgcacaccta
    17941 aaaactacaa caagggacat attgaaggtt ctatttctgc accagtattt acttctgatg
    18001 gtgttgttaa gcgttccgat gaacctactg ctgtagcttt cacagaaact gtaaccggaa
    18061 attccgctct tgaaggaaaa gaaatctatg ttctctgcaa cagtggaaac gcaggtgcaa
    18121 aagctgctac tgttttatta aacgctgcag gatattctct tgacaacatt cacactatta
    18181 cttacggagc aacaggcctt gaagttcgtt acgcattcct tggaacaaac aacgctgtaa
    18241 ccggtgctga agccgtagct gctgttgatt catctgatgt agtaatcatc gatgtacgta
    18301 caacagaaaa ctatgcaaag ggacatctga agaattctat ttctcagcct gtgttctata
    18361 ttgatgaaaa aggcgaagag acagttactc caacaaatca ggacgaatat tcaaaagctt
    18421 tcgcaaaata tgtaacgaac aatctttcta cctttacagg caaaaaagta tacgttctct
    18481 gcaacagtgg ttcaagaggt gcaagagccg ctactgcttt acttgcagac aacggtgttg
    18541 acaaaaacac aatctatacc atcaccggtg gtgcgaaaga tgaaactgta aaaagtgctt
    18601 tcgtaactgt agatggttac aaatttgtat ccggaaacga tgctattaca gctgcaaaag
    18661 aaggaactgc atatgtcatt gatgtgcgtt ctacaaaagc acaggctaaa acaggcactc
    18721 tgaaaggatc catttcacag tctctgtttg acgccgacaa caaacttgac acagctgaag
    18781 ctgaagcact tgaaaaagct ttcaaagaag aaattacttc caaaataaca gaagacaaac
    18841 caatctacat catctgcaac agtggtgcaa gaggggctca gaaagcaacc aaacttcttg
    18901 gagaacttgg ctataacaca agcactaagg aagatggaaa agtatacacc atcacaaacg
    18961 gtgcaaaagg cctggaactc ctgtacgcaa tgtcaggaac agatggaaat gctgaagacg
    19021 gaaaaacagc tgttgctgct gttggaaaag acgatgtagc aatccttgat gtacgtgcaa
    19081 caggcaacta tggtgccgga catttgaaag gttctatctc aacaccagta tttaatgctg
    19141 atggtgttgc aaaaactaca gatgaccagc tttccaaaga tttcacaaaa tatgtaacag
    19201 acaacaaagc cactcttgag aaaaaagatc tctatcttct ctgtaacagt ggtgcaagtg
    19261 gtgcaagagc tgctactgct ttattaaaag ctgccggata tgatcttgca aaagtgcata
    19321 ctatcactgg tggtgcaaaa gatgctgatg taaacgctgc tgcaatctat gtttctgaca
    19381 ctcatgtaat caataaaatg gcagatacaa agaactacct gattcttgat gtacgttcta
    19441 cagcttctta cacaaaagga cacttaaagg gatccctttc ccttccactt tttgacaaag
    19501 ataacaaact tccggatgat ctcgcaaaag catttacaga atatgtaact gctcacaaag
    19561 cagattttga aggaaaaaca atttacgttc tttgcaacag tggagcaaga ggtgctgcaa
    19621 aagcaactca gcttctcaaa gaagccggaa tcaccaacat caaggtattc accatcgaaa
    19681 acggtgcaaa aagtgaagtg atccagaagc attttgtaac agatcctgtc gctgatcctg
    19741 atacaaagaa agacaacaat ggcaaagata acaataaaaa ccagaataac ggtaaaacca
    19801 ctactgctgc tacaacaaag acaggagata ccgctcctat cgctgctctc gcggttgcaa
    19861 tgctcgctgc tcttggcgca atcattgcat tcggtaagaa aaaaattgta aaataataat
    19921 tattcccaaa aaggttacaa aagcgggacg ttgactaaat tgccaacgtc ccgctttttc
    19981 aaatccattc atattcatac gatgttcaga tctcgttgat ctgcttctct tttatttctc
    20041 cagatctcct tccacacacc atctgtaaaa agattcgtca tagttctctg aattttcaaa
    20101 gccacacatt tccattacaa gctgcatata agctgaacgg attcctccgg tacagtaagt
    20161 aataatatga tcctcttttg aaagtcctgc atcttcaaac atcttggtca gatcttcatt
    20221 actctttaat gtactgtcac tgttaaacaa atccgtataa cggatctgga ttgcccctgg
    20281 aagatgtccc ccattttcct ccccatacat tgtctttcca ttatattctt tatctgtacg
    20341 ggtatccaca attttacagt cgtcataaat ctctttcagc tcatccgtat tgatcacatg
    20401 cgtttcatca atcgaatcaa tttctaccga taccggtttc ggctctgcta ctcctttgac
    20461 agtctcaact cctgctgctt tcagtgcttt gatcccgcca tctacgattt tcacatcctc
    20521 atagcctgcc gcgatcagct cccatgcaat cctgccatct tctccccaac ctttctccgc
    20581 atttgaaaaa agcacgattt ccttatcttt tgccagccca agctctccta atctttcgct
    20641 caggcgcttt gtatcaagaa tacatcccca gtttgcatcc cccgcttccc cgtcttcgca
    20701 ggttgccaga tactgccatg tcgttgccac tgcacctttt acagtacctt ttttcgcctc
    20761 atcttcacct cttgcatcca ctacgatgat atcgtccaga ttttctttca catagtcggc
    20821 ggttactaca tactttcctt caaatggttc actgctgtct gatttcgaat tctttgcacc
    20881 acatcctgaa agtgatgaaa tcgcaagaat tcctgcaaga aataatgctg ttcttttcat
    20941 aatcttttct cctcgtctaa tcttctttct tctaactata gcatatcttc aatctattca
    21001 ctaattgatt gtccttatcc cggattaagt atattcatct tttctataaa tcactttttc
    21061 agcagacgca tgatttttct catcggttct gttattttcc agctggttga atttgcatat
    21121 gtctggatca tttcatcctg ctccctgatc ttatcctcat atttcttaag ctgccctgtt
    21181 ttctgttcca tccgtctgcc aagttcatcc agctgttctt cataatgcgc ggcctgcctt
    21241 cgctgtcctt ctatatattc ctgctgctgt tcaatcgctg cattttgttt ttcaagctgt
    21301 tctttctgct gcccgatata ctcatctttc tgtttgagaa tatctttata atacgccagt
    21361 tgctggcttc cttcttcaat ttcacttatc agccatggcg tcttatacat atgttctcca
    21421 ttccactgat acagatcaaa aatatccaga tgaaaatgct ctcttaaagt ctccattgca
    21481 tttgcttctc tcataatctg ccccagcatt tccatccccg ctgctttcag tcccggtact
    21541 tcctctatac atttcatcaa ccagaatgct ttttcaaatt ccagctgtaa atgtgataca
    21601 gaatccggat tccggaaatc ttcccggaaa aactgacaaa atttttcatc cgtcatc
//
